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Antonio Lucacchini

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Lara Testai; Maria Cristina Breschi; Silvio Chericoni; Federica Ciregia; V D'Antongiovanni; Laura Giusti; Antonio Lucacchini; A Marino; Alma Martelli; Vincenzo Calderone
The activation of mitochondrial BK potassium channels contributes to the protective effects of naringenin against myocardial ischemia/reperfusion injury.
Laura Giusti; Antonio Lucacchini
Proteomic studies of formalin-fixed paraffin-embedded tissues.
Donatella Marazziti; Lionella Palego; Ilaria Piano; Andrea Pirone; Lara Schmid; Giovanna Testa; Stefano Baroni; Laura Betti; Fabio Bordi; Franco Borsini; Maura Castagna; Mario Catena-Dell'osso; Claudia Gargini; Gino Giannaccini; Antonio Lucacchini
Serotonin receptor of type 6 (5-HT6) in human prefrontal cortex and hippocampus post-mortem: an immunohistochemical and immunofluorescence study.

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All Publications

2013: Lara Testai; Maria Cristina Breschi; Silvio Chericoni; Federica Ciregia; V D'Antongiovanni; Laura Giusti; Antonio Lucacchini; A Marino; Alma Martelli; Vincenzo Calderone
The activation of mitochondrial BK potassium channels contributes to the protective effects of naringenin against myocardial ischemia/reperfusion injury.
Biochemical pharmacology 2013;85(11):1634-43.
2013: Laura Giusti; Antonio Lucacchini
Proteomic studies of formalin-fixed paraffin-embedded tissues.
Expert review of proteomics 2013;10(2):165-77.
2013: Donatella Marazziti; Lionella Palego; Ilaria Piano; Andrea Pirone; Lara Schmid; Giovanna Testa; Stefano Baroni; Laura Betti; Fabio Bordi; Franco Borsini; Maura Castagna; Mario Catena-Dell'osso; Claudia Gargini; Gino Giannaccini; Antonio Lucacchini
Serotonin receptor of type 6 (5-HT6) in human prefrontal cortex and hippocampus post-mortem: an immunohistochemical and immunofluorescence study.
Neurochemistry international 2013;62(2):182-8.
2012: Gino Giannaccini; Mario Lanza; Laura Betti; Luciano Biondi; Laura Fabbrini; Giovanni Mascia; Antonio Mela; Lionella Palego; Lara Schmid; Antonio Lucacchini
The trace element content of top-soil and wild edible mushroom samples collected in Tuscany, Italy.
Environmental monitoring and assessment 2012;184(12):7579-95.
2012: Elisabetta Volpi; Sergio Berti; Federica Ciregia; Aldo Clerico; Ylenia Da Valle; Gino Giannaccini; Laura Giusti; Antonio Lucacchini
Platelet proteome and clopidogrel response in patients with stable angina undergoing percutaneous coronary intervention.
Clinical biochemistry 2012;45(10-11):758-65.
2012: Barbara Costa; Eleonora Da Pozzo; P Gabelloni; L Lari; Antonio Lucacchini; Marianna Abelli; S Calugi; A Cardini; Giovanni B Cassano; Beatrice Chelli; Stefano Pini; Claudia Martini
Role of translocator protein (18 kDa) in adult separation anxiety and attachment style in patients with depression.
Current molecular medicine 2012;12(4):483-7.
2012: Donatella Marazziti; Lionella Palego; Ilaria Piano; Andrea Pirone; Lara Schmid; Elena Vatteroni; Stefano Baroni; Laura Betti; Fabio Bordi; Franco Borsini; Maura Castagna; Mario Catena-Dell'osso; Claudia Gargini; Gino Giannaccini; Antonio Lucacchini
Distribution of serotonin receptor of type 6 (5-HT₆) in human brain post-mortem. A pharmacology, autoradiography and immunohistochemistry study.
Neurochemical research 2012;37(5):920-7.
2012: Laura Giusti; Pietro Iacconi; Fulvio Basolo; Massimo Chiarugi; Federica Ciregia; Elena Donadio; Gino Giannaccini; Agnese Proietti; Liborio Torregrossa; Tiziana Ventroni; Ylenia Da Valle; Antonio Lucacchini
A proteomic profile of washing fluid from the colorectal tract to search for potential biomarkers of colon cancer.
Molecular bioSystems 2012;8(4):1088-99.
2012: Pietro Iacconi; Salvatore Mazzeo; Agnese Proietti; Liborio Torregrossa; Fulvio Basolo; Federica Ciregia; Ylenia Da Valle; Gianluca Donatini; Gino Giannaccini; Laura Giusti; Antonio Lucacchini
Proteomic approach used in the diagnosis of Riedel's thyroiditis: a case report.
Journal of medical case reports 2012;6(1):103.
2012: Lionella Palego; Gino Giannaccini; Antonio Lucacchini
RP-LC of phenylthiocarbamyl amino acid adducts in plasma acetonitrile extracts: use of multiple internal standards and variable wavelength UV detection.
Methods in molecular biology (Clifton, N.J.) 2012;828():201-17.
2011: Carlotta Granchi; Mario Lanza; Antonio Lucacchini; Marco Macchia; Adriano Martinelli; Marco Mottinelli; Elisa Nardini; Sarabindu Roy; Tiziano Tuccinardi; Laura Betti; Fabio Campinoti; Gino Giannaccini; Filippo Minutolo
Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5.
Bioorganic & medicinal chemistry letters 2011;21(24):7331-6.
2011: Carlotta Granchi; Mario Lanza; Antonio Lucacchini; Marco Macchia; Adriano Martinelli; Laura Betti; Alessio De Simone; Gino Giannaccini; Elisa Giovannetti; Godefridus J Peters; Sarabindu Roy; Irene Salvetti; Rocco Sciarrillo; Tiziano Tuccinardi; Filippo Minutolo
N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation.
European journal of medicinal chemistry 2011;46(11):5398-407.
2011: Maurizio Anzini; Laura Betti; Stefano Alcaro; Carlo Braile; Andrea Cappelli; Simona Daniele; Carla Ghelardini; Gino Giannaccini; Gianluca Giorgi; Vittorio Limongelli; Antonio Lucacchini; Luciana Marinelli; Claudia Martini; Maria Paola Mascia; Ettore Novellino; Francesco Ortuso; Salvatore Valenti; Salvatore Vomero; Lorenzo Di Cesare Mannelli; Giovanni Biggio
New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds.
Journal of medicinal chemistry 2011;54(16):5694-711.
2011: Carlotta Granchi; Sarabindu Roy; Chiara Giacomelli; Marco Macchia; Tiziano Tuccinardi; Adriano Martinelli; Mario Lanza; Laura Betti; Gino Giannaccini; Antonio Lucacchini; Nicola Funel; Leticia G León; Elisa Giovannetti; Godefridus J Peters; Rahul Palchaudhuri; Emilia C Calvaresi; Paul J Hergenrother; Filippo Minutolo
Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
Journal of medicinal chemistry 2011;54(6):1599-612.
2011: Susanna Nencetti; Maria R Mazzoni; Gabriella Ortore; Annalina Lapucci; Janette Giuntini; Elisabetta Orlandini; Irene Banti; Elisa Nuti; Antonio Lucacchini; Gino Giannaccini; Armando Rossello
Synthesis, molecular docking and binding studies of selective serotonin transporter inhibitors.
European journal of medicinal chemistry 2011;46(3):825-34.
2011: Laura Giusti; Filomena Cetani; Federica Ciregia; Ylenia Da Valle; Elena Donadio; Gino Giannaccini; Chiara Banti; Elena Pardi; Federica Saponaro; Fulvio Basolo; Piero Berti; Paolo Miccoli; Aldo Pinchera; Claudio Marcocci; Antonio Lucacchini
A proteomic approach to study parathyroid glands.
Molecular bioSystems 2011;7(3):687-99.
2011: Laura Giusti; Pietro Iacconi; Antonio Lucacchini
Fine-needle aspiration for proteomic study of tumour tissues.
Proteomics. Clinical applications 2011;5(1-2):24-9.
2011: Camillo Giacomelli; Laura Giusti; Alessandra Rossi; Francesca Sernissi; Chiara Baldini; Laura Bazzichi; Stefano Bombardieri; Federica Ciregia; Y Da Valle; Francesca De Feo; Antonio Lucacchini
MALDI-TOF and SELDI-TOF analysis: "tandem" techniques to identify potential biomarker in fibromyalgia.
Reumatismo 2011;63(3):165-70.
2011: Chiara Baldini; Laura Bazzichi; Stefano Bombardieri; Federica Ciregia; Ylenia Da Valle; Elena Donadio; Camillo Giacomelli; Gino Giannaccini; Laura Giusti; Francesca Sernissi; Antonio Lucacchini
Proteomic analysis of saliva: a unique tool to distinguish primary Sjögren's syndrome from secondary Sjögren's syndrome and other sicca syndromes.
Arthritis research & therapy 2011;13(6):R194.
2011: Chiara Baldini; Laura Bazzichi; Stefano Bombardieri; Federica Ciregia; Ylenia Da Valle; Elena Donadio; Valentina Donati; Francesco Ferro; Sara Galimberti; Camillo Giacomelli; Laura Giusti; Antonio Lucacchini
Correspondence between salivary proteomic pattern and clinical course in primary Sjögren syndrome and non-Hodgkin's lymphoma: a case report.
Journal of translational medicine 2011;9():188.
2011: Elena Donadio; Gino Giannaccini; Laura Giusti; Fulvio Basolo; Filomena Cetani; Federica Ciregia; Ylenia Da Valle; Claudio Marcocci; Elena Pardi; Federica Saponaro; Liborio Torregrossa; Antonio Lucacchini
Evaluation of formalin-fixed paraffin-embedded tissues in the proteomic analysis of parathyroid glands.
Proteome science 2011;9(1):29.
2011: Gino Giannaccini; Laura Betti; Lionella Palego; Andrea Pirone; Lara Schmid; Mario Lanza; Laura Fabbrini; Caterina Pelosini; Margherita Maffei; Ferruccio Santini; Aldo Pinchera; Antonio Lucacchini
Serotonin transporter (SERT) and translocator protein (TSPO) expression in the obese ob/ob mouse.
BMC neuroscience 2011;12():18.
2011: Stefano Fogli; Silvia Pellegrini; Barbara Adinolfi; Veronica Mariotti; Erika Melissari; Laura Betti; Laura Fabbrini; Gino Giannaccini; Antonio Lucacchini; Claudio Bardelli; Fabio Stefanelli; Sandra Brunelleschi; Maria Cristina Breschi
Rosiglitazone reverses salbutamol-induced β(2) -adrenoceptor tolerance in airway smooth muscle.
British journal of pharmacology 2011;162(2):378-91.
2010: Donatella Marazziti; Irene Masala; Stefano Baroni; Margherita Polini; Gabriele Massimetti; Gino Giannaccini; Laura Betti; Paola Italiani; Laura Fabbrini; Carolina Caglieresi; Cecilia Moschini; Domenico Canale; Antonio Lucacchini; Mauro Mauri
Male axillary extracts modify the affinity of the platelet serotonin transporter and impulsiveness in women.
Physiology & behavior 2010;100(4):364-8.
2010: Gino Giannaccini; Laura Betti; Lionella Palego; Lara Schmid; Laura Fabbrini; Caterina Pelosini; Claudia Gargini; Ylenia Da Valle; Mario Lanza; Alessandro Marsili; Margherita Maffei; Ferruccio Santini; Paolo Vitti; Aldo Pinchera; Antonio Lucacchini
Human serotonin transporter expression during megakaryocytic differentiation of MEG-01 cells.
Neurochemical research 2010;35(4):628-35.
2010: Laura Giusti; Chiara Baldini; Federica Ciregia; Gino Giannaccini; Camillo Giacomelli; Francesca De Feo; Andrea Delle Sedie; Lucrezia Riente; Antonio Lucacchini; Laura Bazzichi; Stefano Bombardieri
Is GRP78/BiP a potential salivary biomarker in patients with rheumatoid arthritis?
Proteomics. Clinical applications 2010;4(3):315-24.
2010: Donatella Marazziti; Mario Catena Dell'osso; Stefano Baroni; Irene Masala; Bernardo Dell'Osso; Giorgio Consoli; Gino Giannaccini; Laura Betti; Antonio Lucacchini
Alterations of the dopamine transporter in resting lymphocytes of patients with different psychotic disorders.
Psychiatry research 2010;175(1-2):54-7.
2010: Marianna Abelli; Beatrice Chelli; Barbara Costa; Lisa Lari; Alessandra Cardini; Camilla Gesi; Matteo Muti; Antonio Lucacchini; Claudia Martini; Giovanni B Cassano; Stefano Pini
Reductions in platelet 18-kDa translocator protein density are associated with adult separation anxiety in patients with bipolar disorder.
Neuropsychobiology 2010;62(2):98-103.
2010: Donatella Marazziti; Stefano Baroni; Irene Masala; Francesca Golia; Giorgio Consoli; Gabriele Massimetti; Michela Picchetti; Mario Catena Dell'osso; Gino Giannaccini; Laura Betti; Antonio Lucacchini; Antonio Ciapparelli
Impulsivity, gender, and the platelet serotonin transporter in healthy subjects.
Neuropsychiatric disease and treatment 2010;6():9-15.
2009: Barbara Costa; Stefano Pini; Pamela Gabelloni; Eleonora Da Pozzo; Marianna Abelli; Lisa Lari; Matteo Preve; Antonio Lucacchini; Giovanni B Cassano; Claudia Martini
The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals.
Endocrinology 2009;150(12):5438-45.
2009: Donatella Marazziti; Stefano Baroni; Irene Masala; Gino Giannaccini; Laura Betti; Lionella Palego; Mario Catena Dell'Osso; Giorgio Consoli; Maura Castagna; Antonio Lucacchini
[(3)H]-YM-09151-2 binding sites in human brain postmortem.
Neurochemistry international 2009;55(7):643-7.
2009: Laura Bazzichi; Federica Ciregia; Laura Giusti; Chiara Baldini; Gino Giannaccini; Camillo Giacomelli; Francesca Sernissi; Stefano Bombardieri; Antonio Lucacchini
Detection of potential markers of primary fibromyalgia syndrome in human saliva.
Proteomics. Clinical applications 2009;3(11):1296-304.
2009: Barbara Costa; Stefano Pini; Pamela Gabelloni; Marianna Abelli; Lisa Lari; Alessandra Cardini; Matteo Muti; Camilla Gesi; Stefano Landi; Silvana Galderisi; Armida Mucci; Antonio Lucacchini; Giovanni B Cassano; Claudia Martini
Oxytocin receptor polymorphisms and adult attachment style in patients with depression.
Psychoneuroendocrinology 2009;34(10):1506-14.
2009: Barbara Costa; Stefano Pini; Claudia Martini; Marianna Abelli; Pamela Gabelloni; Osele Ciampi; Matteo Muti; Camilla Gesi; Lisa Lari; Alessandra Cardini; Armida Mucci; Paola Bucci; Antonio Lucacchini; Giovanni Battista Cassano
Mutation analysis of oxytocin gene in individuals with adult separation anxiety.
Psychiatry research 2009;168(2):87-93.
2009: Laura Bazzichi; Lionella Palego; Gino Giannaccini; Alessandra Rossi; Francesca De Feo; Camillo Giacomelli; Laura Betti; Laura Giusti; Giovanni Mascia; Stefano Bombardieri; Antonio Lucacchini
Altered amino acid homeostasis in subjects affected by fibromyalgia.
Clinical biochemistry 2009;42(10-11):1064-70.
2009: Barbara Costa; Stefano Pini; Claudia Martini; Marianna Abelli; Pamela Gabelloni; Stefano Landi; Matteo Muti; Camilla Gesi; Lisa Lari; Alessandra Cardini; Silvana Galderisi; Armida Mucci; Antonio Lucacchini; Giovanni Battista Cassano
Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression.
Psychiatric genetics 2009;19(2):110-1.
2009: Donatella Marazziti; Stefano Baroni; Lionella Palego; Irene Masala; Giorgio Consoli; M Catena Dell'osso; Gino Giannaccini; Antonio Lucacchini
Adenylate-cyclase activity in platelets of patients with obsessive-compulsive disorder.
Neuropsychiatric disease and treatment 2009;5():363-7.
2008: Giovannella Strappaghetti; Luciano Mastrini; Antonio Lucacchini; Gino Giannaccini; Laura Betti; Laura Fabbrini
Synthesis and biological affinity of new imidazo- and indol-arylpiperazine derivatives: further validation of a pharmacophore model for alpha(1)-adrenoceptor antagonists.
Bioorganic & medicinal chemistry letters 2008;18(18):5140-5.
2008: Laura Giusti; Pietro Iacconi; Federica Ciregia; Gino Giannaccini; Gian Luca Donatini; Fulvio Basolo; Paolo Miccoli; Aldo Pinchera; Antonio Lucacchini
Fine-needle aspiration of thyroid nodules: proteomic analysis to identify cancer biomarkers.
Journal of proteome research 2008;7(9):4079-88.
2008: Laura Bazzichi; Gino Giannaccini; Laura Betti; Laura Fabbrini; Lara Schmid; Lionella Palego; Camillo Giacomelli; Alessandra Rossi; Laura Giusti; Francesca De Feo; Tiziana Giuliano; Giovanni Mascia; Stefano Bombardieri; Antonio Lucacchini
ATP, calcium and magnesium levels in platelets of patients with primary fibromyalgia.
Clinical biochemistry 2008;41(13):1084-90.
2008: Chiara Baldini; Laura Giusti; Laura Bazzichi; Federica Ciregia; Gino Giannaccini; Camillo Giacomelli; Marica Doveri; Mario Del Rosso; Stefano Bombardieri; Antonio Lucacchini
Association of psoriasin (S100A7) with clinical manifestations of systemic sclerosis: is its presence in whole saliva a potential predictor of pulmonary involvement?
The Journal of rheumatology 2008;35(9):1820-4.
2008: Maurizio Anzini; Carlo Braile; Salvatore Valenti; Andrea Cappelli; Salvatore Vomero; Luciana Marinelli; Vittorio Limongelli; Ettore Novellino; Laura Betti; Gino Giannaccini; Antonio Lucacchini; Carla Ghelardini; Monica Norcini; Francesco Makovec; Gianluca Giorgi; R Ian Fryer
Ethyl 8-fluoro-6-(3-nitrophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate as novel, highly potent, and safe antianxiety agent.
Journal of medicinal chemistry 2008;51(15):4730-43.
2008: Maria Letizia Trincavelli; S Cuboni; Marina Montali; S Santaguida; Antonio Lucacchini; Claudia Martini
Norepinephrine-mediated regulation of 5HT1 receptor functioning in human platelets.
Neurochemical research 2008;33(7):1292-300.
2008: Andrea Pirone; Carla Lenzi; Paolo Marroni; Laura Betti; Giovanni Mascia; Gino Giannaccini; Antonio Lucacchini; Ortenzio Fabiani
Neuropeptide Y in the brain and retina of the adult teleost gilthead seabream (Sparus aurata L.).
Anatomia, histologia, embryologia 2008;37(3):231-40.
2008: Donatella Marazziti; Stefano Baroni; Mario Catena Dell'Osso; Irene Masala; Laura Fabbrini; Laura Betti; Gino Giannaccini; Bernardo Dell'Osso; Antonio Lucacchini
Presence and characterization of the dopamine transporter in human resting lymphocytes.
Neurochemical research 2008;33(6):1011-6.
2008: Gino Giannaccini; Laura Betti; Lionella Palego; Laura Fabbrini; Lara Schmid; Maura Castagna; Laura Giusti; Giovanni Mascia; Antonio Lucacchini
Species comparison of adenosine receptor subtypes in brain and testis.
Neurochemical research 2008;33(5):852-60.
2008: Beatrice Chelli; Stefano Pini; Marianna Abelli; Alessandra Cardini; Lisa Lari; Matteo Muti; Camilla Gesi; Giovanni B Cassano; Antonio Lucacchini; Claudia Martini
Platelet 18 kDa Translocator Protein density is reduced in depressed patients with adult separation anxiety.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2008;18(4):249-54.
2008: Francesco Latrofa; Debora Ricci; Lucia Grasso; Paolo Vitti; Lucio Masserini; Fulvio Basolo; Clara Ugolini; Giovanni Mascia; Antonio Lucacchini; Aldo Pinchera
Characterization of thyroglobulin epitopes in patients with autoimmune and non-autoimmune thyroid diseases using recombinant human monoclonal thyroglobulin autoantibodies.
The Journal of clinical endocrinology and metabolism 2008;93(2):591-6.
2008: Chiara Baldini; Laura Giusti; Laura Bazzichi; Antonio Lucacchini; Stefano Bombardieri
Proteomic analysis of the saliva: a clue for understanding primary from secondary Sjögren's syndrome?
Autoimmunity reviews 2008;7(3):185-91.
2007: Maria Luisa Gelmi; Francesco Caputo; Francesca Clerici; Sara Pellegrino; Gino Giannaccini; Laura Betti; Laura Fabbrini; Lara Schmid; Lionella Palego; Antonio Lucacchini
1-Aminocyclopentane-1,2,4-tricarboxylic acids screening on glutamatergic and serotonergic systems.
Bioorganic & medicinal chemistry 2007;15(24):7581-9.
2007: Laura Giusti; Chiara Baldini; Laura Bazzichi; Stefano Bombardieri; Antonio Lucacchini
Proteomic diagnosis of Sjögren's syndrome.
Expert review of proteomics 2007;4(6):757-67.
2007: Gino Giannaccini; Laura Betti; Andrea Pirone; Lionella Palego; Ortenzio Fabiani; Laura Fabbrini; Giovanni Mascia; Laura Giusti; Marco Macchia; Mario Giusiani; Claudia Martini; Antonio Lucacchini
Short-term effects of 3,4-methylen-dioxy-metamphetamine (MDMA) on 5-HT(1A) receptors in the rat hippocampus.
Neurochemistry international 2007;51(8):496-506.
2007: Laura Giusti; Pietro Iacconi; Federica Ciregia; Gino Giannaccini; Fulvio Basolo; Gianluca Donatini; Paolo Miccoli; Antonio Lucacchini
Proteomic analysis of human thyroid fine needle aspiration fluid.
Journal of endocrinological investigation 2007;30(10):865-9.
2007: Laura Giusti; Laura Bazzichi; Chiara Baldini; Federica Ciregia; Giovanni Mascia; Gino Giannaccini; Mario Del Rosso; Stefano Bombardieri; Antonio Lucacchini
Specific proteins identified in whole saliva from patients with diffuse systemic sclerosis.
The Journal of rheumatology 2007;34(10):2063-9.
2007: Andrea Pirone; Gino Giannaccini; Laura Betti; Antonio Lucacchini; Giovanni Mascia; Laura Fabbrini; Paola Italiani; Angela Uccelli; Carla Lenzi; Ortenzio Fabiani
[3H] muscimol receptors sites in the carp (Cyprinus carpio L.) brain: binding assay and autoradiographic distribution.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2007;148(2):324-31.
2007: Gino Giannaccini; Laura Giusti; Ferruccio Santini; Alessandro Marsili; Laura Betti; Giovanni Mascia; Caterina Pelosini; Stefano Baroni; Federica Ciregia; Laura Fabbrini; Antonio Lucacchini; Paolo Vitti; Aldo Pinchera
Tubby protein in human lymphocytes from normal weight and obese subjects.
Clinical biochemistry 2007;40(11):806-9.
2007: Donatella Marazziti; Antonio Lucacchini; Stefano Baroni; Laura Betti; Mario Catena; Gino Giannaccini; Bernardo Dell'Osso; Irene Masala; Francesco Mungai; Liliana Dell'osso
Presence of D4 dopamine receptors in human prefrontal cortex: a postmortem study.
Revista brasileira de psiquiatria (São Paulo, Brazil : 1999) 2007;29(2):148-52.
2007: Laura Giusti; Chiara Baldini; Laura Bazzichi; Federica Ciregia; Ilaria Tonazzini; Giovanni Mascia; Gino Giannaccini; Stefano Bombardieri; Antonio Lucacchini
Proteome analysis of whole saliva: a new tool for rheumatic diseases--the example of Sjögren's syndrome.
Proteomics 2007;7(10):1634-43.
2006: Laura Bazzichi; Gino Giannaccini; Laura Betti; Paola Italiani; Laura Fabbrini; F Defeo; Camillo Giacomelli; Tiziana Giuliano; Alessandra Rossi; Angela Uccelli; Laura Giusti; Giovanni Mascia; Antonio Lucacchini; Stefano Bombardieri
Peripheral benzodiazepine receptors on platelets of fibromyalgic patients.
Clinical biochemistry 2006;39(9):867-72.
2006: Donatella Marazziti; Stefano Baroni; Laura Fabbrini; Paola Italiani; Mario Catena; Bernardo Dell'Osso; Laura Betti; Gino Giannaccini; Antonio Lucacchini; Giovanni B Cassano
Binding of 3H-WIN-35,428 and 125I-RTI-121 to human platelet membranes.
Neurochemical research 2006;31(3):361-5.
2006: Anna Maria D'Ursi; Laura Giusti; Stefania Albrizio; Francesca Porchia; Carla Esposito; Giuseppe Caliendo; Claudia Gargini; Ettore Novellino; Antonio Lucacchini; Paolo Rovero; Maria R Mazzoni
A membrane-permeable peptide containing the last 21 residues of the G alpha(s) carboxyl terminus inhibits G(s)-coupled receptor signaling in intact cells: correlations between peptide structure and biological activity.
Molecular pharmacology 2006;69(3):727-36.
2006: Claudia Martini; Daniela Tuscano; Maria Letizia Trincavelli; Elisa Cerrai; Maria Bianchi; Antonio Ciapparelli; Lucioni Alessio; Letizia Novelli; Mario Catena; Antonio Lucacchini; Giovanni B Cassano; Liliana Dell'osso
Upregulation of A2A adenosine receptors in platelets from patients affected by bipolar disorders under treatment with typical antipsychotics.
Journal of psychiatric research 2006;40(1):81-8.
2006: Andrea Pirone; Gino Giannaccini; Laura Betti; Antonio Lucacchini; Giovanni Mascia; Laura Fabbrini; Paola Italiani; Angela Uccelli; Carla Lenzi; Ortenzio Fabiani
Autoradiographic localization and binding study of benzodiazepines receptor sites in carp brain (Cyprinus carpio L.).
Journal of chemical neuroanatomy 2006;31(2):139-45.
2006: Donatella Marazziti; Bernardo Dell'Osso; Stefano Baroni; Francesco Mungai; Mario Catena; Paola Rucci; Francesco Albanese; Gino Giannaccini; Laura Betti; Laura Fabbrini; Paola Italiani; Alessandro Del Debbio; Antonio Lucacchini; Liliana Dell'osso
A relationship between oxytocin and anxiety of romantic attachment.
Clinical practice and epidemiology in mental health : CP & EMH 2006;2():28.
2006: Laura Bazzichi; Gino Giannaccini; Laura Betti; Giovanni Mascia; Laura Fabbrini; Paola Italiani; Francesca De Feo; Tiziana Giuliano; Camillo Giacomelli; Alessandra Rossi; Antonio Lucacchini; Stefano Bombardieri
Alteration of serotonin transporter density and activity in fibromyalgia.
Arthritis research & therapy 2006;8(4):R99.
2006: Donatella Marazziti; Bernardo Dell'Osso; Stefano Baroni; Laura Betti; Mario Catena; Gino Giannaccini; Antonio Lucacchini; Giovanni B Cassano
Common alterations in the serotonin transporter in platelets and lymphocytes of psychotic patients.
Pharmacopsychiatry 2006;39(1):35-8.
2005: Stefano Pini; Claudia Martini; Marianna Abelli; Matteo Muti; Camilla Gesi; Marina Montali; Beatrice Chelli; Antonio Lucacchini; Giovanni B Cassano
Peripheral-type benzodiazepine receptor binding sites in platelets of patients with panic disorder associated to separation anxiety symptoms.
Psychopharmacology 2005;181(2):407-11.
2005: Paola Fossa; Marco Pestarino; Giulia Menozzi; Luisa Mosti; Silvia Schenone; Angelo Ranise; Francesco Bondavalli; Maria Letizia Trincavelli; Antonio Lucacchini; Claudia Martini
New pyrazolo[3,4-b]pyridones as selective A(1) adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies.
Organic & biomolecular chemistry 2005;3(12):2262-70.
2005: Antonio Di Stefano; Piera Sozio; Ivana Cacciatore; Alessandra Cocco; Gianfabio Giorgioni; Barbara Costa; Marina Montali; Antonio Lucacchini; Claudia Martini; Giuseppe Spoto; Francesco Di Pietrantonio; Elisabetta Di Matteo; Francesco Pinnen
Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists.
Journal of medicinal chemistry 2005;48(7):2646-54.
2005: Laura Bazzichi; Letizia Trincavelli; Alessandra Rossi; Francesca De Feo; Antonio Lucacchini; Stefano Bombardieri; Claudia Martini
A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis.
Arthritis research & therapy 2005;7(2):R189-95.
2004: Laura Giusti; Barbara Costa; Paolo Viacava; Maria Grazia Castagna; P Iacconi; R E Ricci; M Zaccagnini; Paolo Miccoli; Antonio Lucacchini
Peripheral type benzodiazepine receptor in human parathyroid glands: up-regulation in adenoma.
Journal of endocrinological investigation 2004;27(9):826-31.
2004: Pier Luigi Ferrarini; Laura Betti; Tiziana Cavallini; Gino Giannaccini; Antonio Lucacchini; Clementina Manera; Adriano Martinelli; Gabriella Ortore; Giuseppe Saccomanni; Tiziano Tuccinardi
Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.
Journal of medicinal chemistry 2004;47(12):3019-31.
2004: Andrea Pirone; Carla Lenzi; Laura Betti; Gino Giannaccini; Antonio Lucacchini; Paolo Marroni; Ortenzio Fabiani
Immunohistochemical distribution of neuropeptide Y in the mesencephalon and rhombencephalon of carp, Cyprinus carpio L. (Cyprinidae: Teleostei).
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2004;138(2):175-85.
2004: Claudia Martini; Maria Letizia Trincavelli; Daniela Tuscano; Claudia Carmassi; Antonio Ciapparelli; Antonio Lucacchini; Giovanni B Cassano; Liliana Dell'osso
Serotonin-mediated phosphorylation of extracellular regulated kinases in platelets of patients with panic disorder versus controls.
Neurochemistry international 2004;44(8):627-39.
2004: Gino Giannaccini; Laura Betti; Lionella Palego; Beatrice Chelli; A Gallo; Andrea Pirone; Ortenzio Fabiani; S Bertellotti; Antonio Lucacchini
In vitro effects of lead ions on peripheral benzodiazepine receptors and adenylyl cyclase activity in the mantle of Mytilus galloprovincialis.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2004;137(2):197-206.
2004: Silvia Schenone; Olga Bruno; Francesco Bondavalli; Angelo Ranise; Luisa Mosti; Giulia Menozzi; Paola Fossa; Fabrizio Manetti; Lucia Morbidelli; Letizia Trincavelli; Claudia Martini; Antonio Lucacchini
Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation.
European journal of medicinal chemistry 2004;39(2):153-60.
2004: Daniela Catarzi; Vittoria Colotta; Flavia Varano; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Antonio Lucacchini
1,2,4-Triazolo[1,5-a]quinoxaline derivatives: synthesis and biological evaluation as adenosine receptor antagonists.
Farmaco (Società chimica italiana : 1989) 2004;59(2):71-81.
2004: Janette Giuntini; Laura Giusti; Antonio Lucacchini; Maria R Mazzoni
Modulation of A1 adenosine receptor signaling by peroxynitrite.
Biochemical pharmacology 2004;67(2):375-83.
2004: Donatella Marazziti; Gino Giannaccini; Stefano Baroni; Laura Betti; Laura Giusti; Antonio Lucacchini; Giovanni B Cassano
Absence of NK1 receptors in human blood lymphocytes and granulocytes.
Neuropsychobiology 2004;50(3):221-5.
2004: Liliana Dell'osso; Claudia Carmassi; Lionella Palego; Maria Letizia Trincavelli; Daniela Tuscano; Marina Montali; Simone Sbrana; Antonio Ciapparelli; Antonio Lucacchini; Giovanni B Cassano; Claudia Martini
Serotonin-mediated cyclic AMP inhibitory pathway in platelets of patients affected by panic disorder.
Neuropsychobiology 2004;50(1):28-36.
2004: Vittoria Colotta; Daniela Catarzi; Flavia Varano; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Antonio Lucacchini; Vittoria Colotta
Synthesis and structure-activity relationships of 4-cycloalkylamino-1, 2, 4-triazolo[4, 3-a]quinoxalin-1- one derivatives as A1 and A3 adenosine receptor antagonists.
Archiv der Pharmazie 2004;337(1):35-41.
2004: Laura Giusti; Laura Betti; Gino Giannaccini; Giovanni Mascia; Laura Bazzichi; Antonio Lucacchini
[3H]PK11195 binding sites in human neutrophils: effect of fMLP stimulation and modulation in rheumatic diseases.
Clinical biochemistry 2004;37(1):61-6.
2003: Vittoria Colotta; Daniela Catarzi; Flavia Varano; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Antonio Lucacchini
Synthesis of 4-amino-6-(hetero)arylalkylamino-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent A(2A) adenosine receptor antagonists.
Bioorganic & medicinal chemistry 2003;11(24):5509-18.
2003: Maria Letizia Trincavelli; Alessandra Falleni; Beatrice Chelli; Daniela Tuscano; Barbara Costa; Vittorio Gremigni; Antonio Lucacchini; Claudia Martini
A(2A) adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosis.
Biochemical pharmacology 2003;66(10):1953-62.
2003: Giuliana Biagi; Irene Giorgi; Oreste Livi; Antonio Nardi; Federica Pacchini; Valerio Scartoni; Antonio Lucacchini
N6-cycloalkyl-2-phenyl-3-deaza-8-azaadenines: a new class of A1 adenosine receptor ligands. A comparison with the corresponding adenines and 8-azaadenines.
European journal of medicinal chemistry 2003;38(11-12):983-90.
2003: Giuliana Biagi; Irene Giorgi; Michele Leonardi; Oreste Livi; Federica Pacchini; Valerio Scartoni; Barbara Costa; Antonio Lucacchini
New N6- or N(9)-hydroxyalkyl substituted 8-azaadenines or adenines as effective A1 adenosine receptor ligands.
European journal of medicinal chemistry 2003;38(9):801-10.
2003: Vittoria Colotta; Daniela Catarzi; Flavia Varano; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Antonio Lucacchini
Synthesis and structure-activity relationships of a new set of 1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as adenosine receptor antagonists.
Bioorganic & medicinal chemistry 2003;11(16):3541-50.
2003: Laura Giusti; Simone Taddei; Francesca Ceccarelli; Silvio Chericoni; Gianni Bigini; Antonio Lucacchini; Maria R Mazzoni
Alkylation of sulfhydryl groups on Galpha(s/olf) subunits by N-ethylmaleimide: regulation by guanine nucleotides.
Biochimica et biophysica acta 2003;1613(1-2):7-14.
2003: Donatella Marazziti; Gino Giannaccini; Annalisa Giromella; Laura Betti; Debora Pesce; Irma Nardi; Alessandra Rossi; Antonio Lucacchini; Giovanni B Cassano
[3H]-ketanserin binding sites in different psychiatric disorders.
Neurochemistry international 2003;42(6):511-6.
2003: Andrea Pirone; Laura Betti; Giovanni Mascia; Gino Giannaccini; Antonio Lucacchini; Ortenzio Fabiani
Autoradiographic distribution of neuropeptide Y binding sites in the brain of the carp Cyprinus carpio L. (Cyprinidae, Teleostei).
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2003;134(4):757-62.
2003: Francesca Ceccarelli; Maria C Scavuzzo; Laura Giusti; Gianni Bigini; Barbara Costa; Vittoria Carnicelli; Riccardo Zucchi; Antonio Lucacchini; Maria R Mazzoni
ETA receptor-mediated Ca2+ mobilisation in H9c2 cardiac cells.
Biochemical pharmacology 2003;65(5):783-93.
2003: Laura Bazzichi; Laura Betti; Gino Giannaccini; Alessandra Rossi; Antonio Lucacchini
Peripheral-type benzodiazepine receptors in human mononuclear cells of patients affected by osteoarthritis, rheumatoid arthritis or psoriasic arthritis.
Clinical biochemistry 2003;36(1):57-60.
2003: Donatella Marazziti; Paola Rucci; Elena Di Nasso; Irene Masala; Stefano Baroni; Alessandra Rossi; Gino Giannaccini; Francesco Mengali; Antonio Lucacchini
Jealousy and subthreshold psychopathology: a serotonergic link.
Neuropsychobiology 2003;47(1):12-6.
2003: Laura Betti; Gino Giannaccini; Marco Nigro; Sabina Dianda; Vittorio Gremigni; Antonio Lucacchini
Studies of peripheral benzodiazepine receptors in mussels: comparison between a polluted and a nonpolluted site.
Ecotoxicology and environmental safety 2003;54(1):36-42.
2002: Laura Bazzichi; ML Ciompi; Laura Betti; Alessandra Rossi; Daniela Melchiorre; marcello fiorini; Gino Giannaccini; Antonio Lucacchini
Impaired glutathione reductase activity and levels of collagenase and elastase in synovial fluid in rheumatoid arthritis.
Clinical and experimental rheumatology 2002;20(6):761-6.
2002: Francesco Bondavalli; Maurizio Botta; Olga Bruno; Andrea Ciacci; Federico Corelli; Paola Fossa; Antonio Lucacchini; Fabrizio Manetti; Claudia Martini; Giulia Menozzi; Luisa Mosti; Angelo Ranise; Silvia Schenone; Andrea Tafi; Maria Letizia Trincavellic
Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists.
Journal of medicinal chemistry 2002;45(22):4875-87.
2002: Donatella Marazziti; Liliana Dell'osso; Irene Masala; Stefano Baroni; Silvio Presta; Gino Giannaccini; Elena Di Nasso; Francesco Mungai; Antonio Lucacchini; Giovanni B Cassano
Decreased inhibitory activity of PKC in OCD patients after six months of treatment.
Psychoneuroendocrinology 2002;27(7):769-76.
2002: Maria Letizia Trincavelli; Daniela Tuscano; Matteo Marroni; Karl-Norbert Klotz; Antonio Lucacchini; Claudia Martini
Involvement of mitogen protein kinase cascade in agonist-mediated human A(3) adenosine receptor regulation.
Biochimica et biophysica acta 2002;1591(1-3):55-62.
2002: Maria Letizia Trincavelli; Barbara Costa; Daniela Tuscano; Antonio Lucacchini; Claudia Martini
Up-regulation of A(2A) adenosine receptors by proinflammatory cytokines in rat PC12 cells.
Biochemical pharmacology 2002;64(4):625-31.
2002: Donatella Marazziti; Lionella Palego; Annalisa Giromella; Maria R Mazzoni; Franco Borsini; Norbert Mayer; Antonio Giuseppe Naccarato; Antonio Lucacchini; Giovanni B Cassano
Region-dependent effects of flibanserin and buspirone on adenylyl cyclase activity in the human brain.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2002;5(2):131-40.
2002: Ola A El-Sayed; Nargues S Habib; Nafiz Oncu Can; Barbara Costa; Antonio Lucacchini; Claudia Martini
Synthesis and benzodiazepine receptor binding activity of 2, 9-disubstituted quinolino[2', 3'-5, 4](3-pyrazolino)[3, 2-b]purin-4-ones.
Archiv der Pharmazie 2002;335(5):207-12.
2002: Francesca Salvetti; Paolo Cecchetti; Damir Janigro; Antonio Lucacchini; Luca Benzi; Claudia Martini
Insulin permeability across an in vitro dynamic model of endothelium.
Pharmaceutical research 2002;19(4):445-50.
2002: Lionella Palego; Luciano Biondi; Gino Giannaccini; Nannina Sarno; Simona Elmi; Antonio Ciapparelli; Giovanni B Cassano; Antonio Lucacchini; Claudia Martini; Liliana Dell'osso
Clozapine, norclozapine plasma levels, their sum and ratio in 50 psychotic patients: influence of patient-related variables.
Progress in neuro-psychopharmacology & biological psychiatry 2002;26(3):473-80.
2002: Antonio Di Stefano; Piera Sozio; Grazia Luisi; Ivana Cacciatore; Barbara Mosciatti; Barbara Costa; Antonio Lucacchini; Claudia Martini; Francesco Pinnen
Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands.
Farmaco (Società chimica italiana : 1989) 2002;57(4):303-13.
2002: Maria Letizia Trincavelli; Lorella Marselli; Alessandra Falleni; Vittorio Gremigni; Esther Ragge; Francesco Dotta; Carmela Santangelo; Piero Marchetti; Antonio Lucacchini; Claudia Martini
Upregulation of mitochondrial peripheral benzodiazepine receptor expression by cytokine-induced damage of human pancreatic islets.
Journal of cellular biochemistry 2002;84(3):636-44.
2001: Marco Macchia; teresina laragione; Simone Bertini; Valeria Di Bussolo; L Gattuso; Marco Gesi; Mahmoud Hamdan; Karl-Norbert Klotz; T Laragione; Antonio Lucacchini; Filippo Minutolo; Susanna Nencetti; Chiara Papi; Daniela Tuscano; Claudia Martini
7-Nitrobenzofurazan (NBD) derivatives of 5'-N-ethylcarboxamidoadenosine (NECA) as new fluorescent probes for human A(3) adenosine receptors.
Bioorganic & medicinal chemistry letters 2001;11(23):3023-6.
2001: Donatella Marazziti; Liliana Dell'osso; Alessandra Rossi; Irene Masala; Stefano Baroni; Antonella Armani; Gino Giannaccini; Elena Di Nasso; Antonio Lucacchini; Giovanni B Cassano
Decreased platelet [3H]paroxetine binding sites in suicide attempters.
Psychiatry research 2001;103(2-3):125-31.
2001: Francesca Ceccarelli; Laura Giusti; Gianni Bigini; Barbara Costa; D Grillotti; E Fiumalbi; Antonio Lucacchini; Maria R Mazzoni
Regulation of agonist binding to rat ET(B) receptors by cations and GTPgammaS.
Biochemical pharmacology 2001;62(5):537-45.
2001: GM Cingolani; Antonio Di Stefano; F Napolitani; Barbara Mosciatti; Gianfabio Giorgioni; N Cinone; Luigi Brunetti; Grazia Luisi; Barbara Michelotto; Giustino Orlando; Barbara Costa; Antonio Lucacchini; Claudia Martini; F Claudi
Synthesis and preliminary pharmacological evaluation of 5-hydroxy- and 5,6-dihydroxy-1,2,3,7,12,12a-hexahydrobenzo[5,6]cyclohepta[1,2,3-ij]isoquinoline derivatives as dopamine receptor ligands.
Bioorganic & medicinal chemistry 2001;9(6):1447-58.
2001: Beatrice Chelli; Alessandra Falleni; F Salvetti; Vittorio Gremigni; Antonio Lucacchini; Claudia Martini
Peripheral-type benzodiazepine receptor ligands: mitochondrial permeability transition induction in rat cardiac tissue.
Biochemical pharmacology 2001;61(6):695-705.
2001: Donatella Marazziti; Laura Betti; Gino Giannaccini; Alessandra Rossi; Irene Masala; Stefano Baroni; Giovanni B Cassano; Antonio Lucacchini
Distribution of [3H]GR65630 binding in human brain postmortem.
Neurochemical research 2001;26(3):187-90.
2001: Laura Betti; Gino Giannaccini; M Gori; M Bistocchi; Antonio Lucacchini
[3H]Ro 15-1788 binding sites to brain membrane of the saltwater Mugil cephalus.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2001;128(3):291-7.
2001: Donatella Marazziti; Stefano Baroni; Irene Masala; Elena Di Nasso; Gino Giannaccini; Laura Betti; Antonio Lucacchini; Giovanni B Cassano
Correlation between platelet alpha(2)-adrenoreceptors and symptom severity in major depression.
Neuropsychobiology 2001;44(3):122-5.
2001: Donatella Marazziti; Stefano Baroni; Alessandra Rossi; Irene Masala; Gino Giannaccini; V Gori; Antonio Lucacchini; Giovanni B Cassano
Pharmacological characterization of the serotonin transporter in young and elderly subjects.
Neuropsychobiology 2001;44(2):78-83.
2000: Maria Letizia Trincavelli; Daniela Tuscano; Paolo Cecchetti; Alessandra Falleni; Luca Benzi; Karl-Norbert Klotz; Vittorio Gremigni; Flaminio Nicola Cattabeni; Antonio Lucacchini; Claudia Martini
Agonist-induced internalization and recycling of the human A(3) adenosine receptors: role in receptor desensitization and resensitization.
Journal of neurochemistry 2000;75(4):1493-501.
2000: Vittoria Colotta; Daniela Catarzi; Flavia Varano; L Cecchi; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Antonio Lucacchini
Synthesis and structure-activity relationships of a new set of 2-arylpyrazolo[3,4-c]quinoline derivatives as adenosine receptor antagonists.
Journal of medicinal chemistry 2000;43(16):3118-24.
2000: Pier Luigi Ferrarini; Claudio Mori; Clementina Manera; Adriano Martinelli; F Mori; Giuseppe Saccomanni; Pier Luigi Barili; Laura Betti; Gino Giannaccini; Letizia Trincavelli; Antonio Lucacchini
A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives.
Journal of medicinal chemistry 2000;43(15):2814-23.
2000: Maria R Mazzoni; Simone Taddei; Laura Giusti; Paolo Rovero; C Galoppini; Anna Maria D'Ursi; Stefania Albrizio; Antonio Triolo; Ettore Novellino; Giovanni Greco; Antonio Lucacchini; Heidi E Hamm
A galpha(s) carboxyl-terminal peptide prevents G(s) activation by the A(2A) adenosine receptor.
Molecular pharmacology 2000;58(1):226-36.
2000: Lionella Palego; Donatella Marazziti; Luciano Biondi; Gino Giannaccini; Nannina Sarno; Antonella Armani; Antonio Lucacchini; Giovanni B Cassano; Liliana Dell'osso
Simultaneous plasma level analysis of clomipramine, N-desmethylclomipramine, and fluvoxamine by reversed-phase liquid chromatography.
Therapeutic drug monitoring 2000;22(2):190-4.
2000: Vittoria Colotta; Daniela Catarzi; Flavia Varano; L Cecchi; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Antonio Lucacchini
1,2,4-Triazolo[4,3-a]quinoxalin-1-one: a versatile tool for the synthesis of potent and selective adenosine receptor antagonists.
Journal of medicinal chemistry 2000;43(6):1158-64.
2000: L Bertelli; Giuliana Biagi; Irene Giorgi; Oreste Livi; Clementina Manera; Valerio Scartoni; Antonio Lucacchini; Gino Giannaccini; Pier Luigi Barili
Substituted 1,2,3-triazolo[1,5-a]quinazolines: synthesis and binding to benzodiazepine and adenosine receptors.
European journal of medicinal chemistry 2000;35(3):333-41.
2000: Lionella Palego; Annalisa Giromella; Donatella Marazziti; Gino Giannaccini; Franco Borsini; Federico Bigazzi; Antonio Giuseppe Naccarato; Antonio Lucacchini; Giovanni B Cassano; Maria R Mazzoni
Lack of stereoselectivity of 8-hydroxy-2(di-N-propylamino)tetralin-mediated inhibition of forskolin-stimulated adenylyl cyclase activity in human pre- and post-synaptic brain regions.
Neurochemistry international 2000;36(3):225-32.
2000: F Salvetti; Beatrice Chelli; Marco Gesi; Antonio Pellegrini; Gino Giannaccini; Antonio Lucacchini; Claudia Martini
Effect of noise exposure on rat cardiac peripheral benzodiazepine receptors.
Life sciences 2000;66(13):1165-75.
2000: Gino Giannaccini; Laura Betti; Claudia Martini; M Bistocchi; Giovanni Mascia; M Piccolino; Antonio Lucacchini
Autoradiographic distribution of peripheral benzodiazepine receptors in the retina of the albino rabbit, Lepus cunicula.
Neuroscience letters 2000;280(1):37-40.
2000: Lionella Palego; Annalisa Giromella; Maria R Mazzoni; Donatella Marazziti; Antonio Giuseppe Naccarato; Gino Giannaccini; Giovanni B Cassano; Antonio Lucacchini
Gender and age-related variation in adenylyl cyclase activity in the human prefrontal cortex, hippocampus and dorsal raphe nuclei.
Neuroscience letters 2000;279(1):53-6.
2000: Donatella Marazziti; Irene Masala; Alessandra Rossi; Eric Hollander; Silvio Presta; Gino Giannaccini; Maria R Mazzoni; Liliana Dell'osso; Antonio Lucacchini; Giovanni B Cassano
Increased inhibitory activity of protein kinase C on the serotonin transporter in OCD.
Neuropsychobiology 2000;41(4):171-7.
1999: Donatella Marazziti; Liliana Dell'osso; Silvio Presta; Chiara Pfanner; Alessandra Rossi; Irene Masala; Stefano Baroni; Gino Giannaccini; Antonio Lucacchini; Giovanni B Cassano
Platelet [3H]paroxetine binding in patients with OCD-related disorders.
Psychiatry research 1999;89(3):223-8.
1999: Donatella Marazziti; Alessandra Rossi; Gino Giannaccini; Katia Zavaglia; Liliana Dell'osso; Antonio Lucacchini; Giovanni B Cassano
Distribution and characterization of [3H]mesulergine binding in human brain postmortem.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1999;10(1):21-6.
1999: Alessandra Falleni; Maria Letizia Trincavelli; Marco Macchia; F Salvetti; Mahmoud Hamdan; F Calvani; Vittorio Gremigni; Antonio Lucacchini; Claudia Martini
A(1) adenosine receptors in human neutrophils: direct binding and electron microscope visualization.
Journal of cellular biochemistry 1999;75(2):235-44.
1999: Maria R Mazzoni; Maria Cristina Breschi; Francesca Ceccarelli; N Lazzeri; Laura Giusti; Paola Nieri; Antonio Lucacchini
Suc-[Glu9,Ala11,15]-endothelin-1 (8-21), IRL 1620, identifies two populations of ET(B) receptors in guinea-pig bronchus.
British journal of pharmacology 1999;127(6):1406-14.
1999: Gabriella Guerrini; Annarella Costanzo; Fabrizio Bruni; Giovanna Ciciani; Silvia Selleri; Paola Gratteri; Barbara Costa; Claudia Martini; Antonio Lucacchini
Benzodiazepine receptor ligands. III. Synthesis and biological evaluation of 2- and/or 3-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides.
Farmaco (Società chimica italiana : 1989) 1999;54(6):375-89.
1999: Annarella Costanzo; Gabriella Guerrini; Giovanna Ciciani; Fabrizio Bruni; Silvia Selleri; Barbara Costa; Claudia Martini; Antonio Lucacchini; P M Aiello; A Ipponi
Benzodiazepine receptor ligands. 4. Synthesis and pharmacological evaluation of 3-heteroaryl-8-chloropyrazolo[5,1-c][1,2,4] benzotriazine 5-oxides.
Journal of medicinal chemistry 1999;42(12):2218-26.
1999: Donatella Marazziti; Alessandra Rossi; Irene Masala; Alessandro Rotondo; Lionella Palego; Maria R Mazzoni; Gino Giannaccini; Antonio Lucacchini; Giovanni B Cassano
Regulation of the platelet serotonin transporter by protein kinase C in the young and elderly.
Biological psychiatry 1999;45(4):443-7.
1999: Vittoria Colotta; Daniela Catarzi; Flavia Varano; L Cecchi; Guido Filacchioni; Claudia Martini; Letizia Trincavelli; Antonio Lucacchini
4-Amino-6-benzylamino-1,2-dihydro-2-phenyl-1,2,4-triazolo [4,3-alpha]-quinoxalin-1-one: a new A2A adenosine receptor antagonist with high selectivity versus A1 receptors.
Archiv der Pharmazie 1999;332(2):39-41.
1999: Lionella Palego; Annalisa Giromella; Donatella Marazziti; Franco Borsini; Antonio Giuseppe Naccarato; Gino Giannaccini; Antonio Lucacchini; Giovanni B Cassano; Maria R Mazzoni
Effects of postmortem delay on serotonin and (+)8-OH-DPAT-mediated inhibition of adenylyl cyclase activity in rat and human brain tissues.
Brain research 1999;816(1):165-74.
1999: Donatella Marazziti; Alessandra Rossi; Liliana Dell'osso; Lionella Palego; Giovanni P A Placidi; Gino Giannaccini; Antonio Lucacchini; Giovanni B Cassano
Decreased platelet 3H-paroxetine binding in untreated panic disorder patients.
Life sciences 1999;65(25):2735-41.
1998: Marco Macchia; F Salvetti; Silvia Barontini; F Calvani; Marco Gesi; Mahmoud Hamdan; Antonio Lucacchini; A Pellegrini; Paola Soldani; Claudia Martini
Fluorescent probes for adenosine receptors: synthesis and biology of N6-dansylaminoalkyl-substituted NECA derivatives.
Bioorganic & medicinal chemistry letters 1998;8(22):3223-8.
1998: Gino Giannaccini; ROBERTO LUPI; Maria Letizia Trincavelli; Renzo Navalesi; Laura Betti; Piero Marchetti; Antonio Lucacchini; SILVIA DEL GUERRA; Claudia Martini
Characterization of sulfonylurea receptors in isolated human pancreatic islets.
Journal of cellular biochemistry 1998;71(2):182-8.
1998: Antonio Da Settimo; Giampaolo Primofiore; Federico Da Settimo; Anna Maria Marini; Ettore Novellino; Giovanni Greco; Marco Gesi; Claudia Martini; Gino Giannaccini; Antonio Lucacchini
N'-Phenylindol-3-ylglyoxylohydrazide derivatives: synthesis, structure-activity relationships, molecular modeling studies, and pharmacological action on brain benzodiazepine receptors.
Journal of medicinal chemistry 1998;41(20):3821-30.
1998: Marco Macchia; Silvia Barontini; Francesca Ceccarelli; C Galoppini; Laura Giusti; Mahmoud Hamdan; Antonio Lucacchini; Adriano Martinelli; E Menchini; Maria R Mazzoni; Roberto P Revoltella; F Romagnoli; Paolo Rovero
Toward the rational development of peptidomimetic analogs of the C-terminal endothelin hexapeptide: development of a theoretical model.
Farmaco (Società chimica italiana : 1989) 1998;53(8-9):545-56.
1998: Donatella Marazziti; Alessandra Rossi; Gino Giannaccini; Stefano Baroni; Antonio Lucacchini; Giovanni B Cassano
Presence and characterization of the serotonin transporter in human resting lymphocytes.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1998;19(2):154-9.
1998: Donatella Marazziti; Alessandra Rossi; Lionella Palego; A Barsanti; M Carrai; Gino Giannaccini; P Serra; Antonio Lucacchini; Giovanni B Cassano
Effect of aging and sex on the [3H]-paroxetine binding to human platelets.
Journal of affective disorders 1998;50(1):11-5.
1998: Palmarisa Franchetti; Loredana Cappellacci; S Marchetti; L Trincavelli; Claudia Martini; M R Mazzoni; Antonio Lucacchini; Mario Grifantini
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
Journal of medicinal chemistry 1998;41(10):1708-15.
1998: B Costa; Laura Giusti; Claudia Martini; Antonio Lucacchini
Chemical modification of the dihydropyridines binding sites by lysine reagent, pyridoxal 5'-phosphate.
Neurochemistry international 1998;32(4):361-4.
1998: Vittoria Colotta; Daniela Catarzi; Flavia Varano; Fabrizio Melani; Guido Filacchioni; L Cecchi; Letizia Trincavelli; Claudia Martini; Antonio Lucacchini
Synthesis and A1 and A2A adenosine binding activity of some pyrano[2,3-c]pyrazol-4-ones.
Farmaco (Società chimica italiana : 1989) 1998;53(3):189-96.
1998: Laura Betti; Giuliana Biagi; Gino Giannaccini; Irene Giorgi; Oreste Livi; Antonio Lucacchini; Clementina Manera; Valerio Scartoni
Novel 3-aralkyl-7-(amino-substituted)-1,2,3-triazolo[4,5-d]pyrimidines with high affinity toward A1 adenosine receptors.
Journal of medicinal chemistry 1998;41(5):668-73.
1998: Claudia Martini; Letizia Trincavelli; marcello fiorini; F Salvetti; Umberto Montali; Alessandra Falleni; Vittorio Gremigni; Antonio Lucacchini
A1 adenosine receptors in human neutrophils. Electron microscope localization.
Advances in experimental medicine and biology 1998;431():107-11.
1998: Claudia Martini; Letizia Trincavelli; marcello fiorini; M Nardi; Laura Bazzichi; Antonio Lucacchini
Effect of FMLP stimulation on [3H]-NECA binding to adenosine receptors in neutrophils membranes.
Advances in experimental medicine and biology 1998;431():89-94.
1997: Gino Giannaccini; Laura Betti; M Correani; M Dini; Laura Giusti; Antonio Lucacchini
Binding of the benzodiazepine ligand [3H]-Ro 15-1788 to brain membrane of the saltwater fish Mullus surmuletus.
Neurochemistry international 1997;31(6):781-7.
1997: Antonio Da Settimo; Giampaolo Primofiore; Anna Maria Marini; Federico Da Settimo; V Nuti; Claudia Martini; Letizia Trincavelli; Antonio Lucacchini
Isosteric replacement of amide by ester function. Synthesis and benzodiazepine receptor affinity of indol-3-ylglyoxylyl ester derivatives.
Farmaco (Società chimica italiana : 1989) 1997;52(6-7):421-8.
1997: Donatella Marazziti; A Rossi; Lionella Palego; Gino Giannaccini; Antonio Giuseppe Naccarato; Antonio Lucacchini; Giovanni B Cassano
[3H]ketanserin binding in human brain postmortem.
Neurochemical research 1997;22(6):753-7.
1997: Lionella Palego; Donatella Marazziti; A Rossi; Gino Giannaccini; Antonio Giuseppe Naccarato; Antonio Lucacchini; Giovanni B Cassano
Apparent absence of aging and gender effects on serotonin 1A receptors in human neocortex and hippocampus.
Brain research 1997;758(1-2):26-32.
1997: Claudia Martini; Letizia Trincavelli; Antonio Lucacchini
Chemical modifications of striatal A2A adenosine receptors: a possible role for tyrosine at the ligand binding sites.
Biochimica et biophysica acta 1997;1326(1):67-74.
1997: Maria R Mazzoni; Laura Giusti; E Rossi; Simone Taddei; Antonio Lucacchini
Role of cysteine residues of rat A2a adenosine receptors in agonist binding.
Biochimica et biophysica acta 1997;1324(1):159-70.
1997: Laura Giusti; Piero Marchetti; Letizia Trincavelli; ROBERTO LUPI; Claudia Martini; Antonio Lucacchini; SILVIA DEL GUERRA; C Tellini; Mario Carmellini; Renzo Navalesi
Peripheral benzodiazepine receptors in isolated human pancreatic islets.
Journal of cellular biochemistry 1997;64(2):273-7.
1997: Lionella Palego; Donatella Marazziti; Alessandro Rotondo; A Batistini; Antonio Lucacchini; Antonio Giuseppe Naccarato; G Bevilacqua; Franco Borsini; H Ladinsky; Giovanni B Cassano
Further characterisation of [3H]8-hydroxy-2-(di-N-propylamino)tetralin binding sites in human brain postmortem.
Neurochemistry international 1997;30(2):149-57.
1997: Giuliana Biagi; Irene Giorgi; Oreste Livi; Valerio Scartoni; Antonio Lucacchini
Synthesis of 4,6-disubstituted- and 4,5,6-trisubstituted-2-phenyl-pyrimidines and their affinity towards A1 adenosine receptors.
Farmaco (Società chimica italiana : 1989) 1997;52(1):61-5.
1996: Antonio Da Settimo; Giampaolo Primofiore; Federico Da Settimo; Anna Maria Marini; E Novellino; G Greco; Claudia Martini; Gino Giannaccini; Antonio Lucacchini
Synthesis, structure-activity relationships, and molecular modeling studies of N-(indol-3-ylglyoxylyl)benzylamine derivatives acting at the benzodiazepine receptor.
Journal of medicinal chemistry 1996;39(26):5083-91.
1996: B Costa; Laura Giusti; Claudia Martini; Antonio Lucacchini
2,3-Butanedione inactivates the [3H]nitrendipine binding sites, whereas diethylpyrocarbonate does not.
Neurochemistry international 1996;29(6):623-7.
1996: G Chiellini; Gino Giannaccini; Claudia Martini; Antonio Lucacchini
Binding of beta 1-adrenoceptor antagonist [3H]CGP 26505 in rat cerebral cortex and sinus atrial node.
Neurochemical research 1996;21(10):1149-53.
1996: Giuliana Biagi; Irene Giorgi; Oreste Livi; Clementina Manera; Valerio Scartoni; Antonio Lucacchini; G Senatore
1,2,3-Triazolo [4,5-d] pyridazines--V. Preparation and adenosine receptor binding of new 4-amino derivatives.
Farmaco (Società chimica italiana : 1989) 1996;51(8-9):601-8.
1996: Piero Marchetti; Letizia Trincavelli; Rosa Giannarelli; Laura Giusti; Alberto Coppelli; Claudia Martini; Renzo Navalesi; Antonio Lucacchini
Characterization of peripheral benzodiazepine receptors in purified large mammal pancreatic islets.
Biochemical pharmacology 1996;51(11):1437-42.
1996: B Costa; Laura Giusti; Claudia Martini; Antonio Lucacchini
Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain.
Neurochemical research 1996;21(5):537-40.
1996: Alessandro Rotondo; Gino Giannaccini; Laura Betti; G Chiellini; Donatella Marazziti; C Martin; Antonio Lucacchini; Giovanni B Cassano
The serotonin transporter from human brain: purification and partial characterization.
Neurochemistry international 1996;28(3):299-307.
1996: Giuliano Grandolini; Valeria Ambrogi; Luana Perioli; Gino Giannaccini; Antonio Lucacchini; Claudia Martini
Studies on annelated 1,4-benzothiazines and 1,5-benzothiazepines. X--Synthesis and inhibition of benzodiazepine receptor binding of new 1,4-thiazine and 1,5-thiazepine polycondensed heterocycles with steroidal structure.
Farmaco (Società chimica italiana : 1989) 1996;51(3):203-7.
1996: Giuliana Biagi; Irene Giorgi; Oreste Livi; Valerio Scartoni; S Velo; Antonio Lucacchini; G Senatore; B De Santis; Adriano Martinelli
1,2,3-triazolo[1.5-a]quinazolines: synthesis, benzodiazepine receptor binding and theoretical calculations.
Farmaco (Società chimica italiana : 1989) 1996;51(2):131-6.
1996: Donatella Marazziti; A Rossi; Angelo Gemignani; Gino Giannaccini; Chiara Pfanner; A Milanfranchi; Silvio Presta; Antonio Lucacchini; Giovanni B Cassano
Decreased platelet 3H-paroxetine binding in obsessive-compulsive patients.
Neuropsychobiology 1996;34(4):184-7.
1996: Donatella Marazziti; Gino Giannaccini; Claudia Martini; M Simoncini; Liliana Dell'osso; Antonio Lucacchini; Giovanni B Cassano
Benzodiazepine binding inhibitory activity: new supportive findings on its presence in psychiatric patients and further biochemical analyses.
Neuropsychobiology 1996;34(1):9-13.
1995: Silvia Selleri; Fabrizio Bruni; Annarella Costanzo; Gabriella Guerrini; M L Casilli; Laura Giusti; Antonio Lucacchini; Claudia Martini
New 2,3-substituted 4,7-dihydro-6-(1'H-pyrazol-3'-yl)pyrazolo[1,5-a] pyrimidin-7-ones and related compounds: synthesis and benzodiazepine receptor binding study.
Farmaco (Società chimica italiana : 1989) 1995;50(10):679-87.
1995: Maria R Mazzoni; R S Buffoni; Laura Giusti; Antonio Lucacchini
Characterization of a low affinity binding site for N6-substituted adenosine derivatives in rat testis membranes.
Journal of receptor and signal transduction research 1995;15(7-8):905-29.
1995: Stefano Corsano; Giovannella Strappaghetti; R Scapicchi; Antonio Lucacchini; G Senatore
Structure-activity relationships in a series of 8-substituted xanthines as bronchodilator and A1-adenosine receptor antagonists.
Archiv der Pharmazie 1995;328(9):654-8.
1995: Daniela Catarzi; L Cecchi; Vittoria Colotta; Guido Filacchioni; Flavia Varano; Claudia Martini; L Giousti; Antonio Lucacchini
Synthesis of some 2-aryl-1,2,4-triazolo[1,5-c][1,3]benzoxazin-5-ones as tools to define the essential pharmacophoric descriptors of a benzodiazepine receptor ligand.
Journal of medicinal chemistry 1995;38(12):2196-201.
1995: Antonio Da Settimo; Giampaolo Primofiore; Federico Da Settimo; Anna Maria Marini; E Novellino; G Greco; Claudia Martini; G Senatore; Antonio Lucacchini
Synthesis of 3-(2'-furoyl)indole derivatives as potential new ligands at the benzodiazepine receptor, structurally more restrained analogues of indoleglyoxylylamides.
Farmaco (Società chimica italiana : 1989) 1995;50(5):311-20.
1995: Daniela Catarzi; L Cecchi; Vittoria Colotta; Guido Filacchioni; Claudia Martini; P Tacchi; Antonio Lucacchini
Tricyclic heteroaromatic systems. Synthesis and A1 and A2a adenosine binding activities of some 1-aryl-1,4-dihydro-3-methyl[1]benzopyrano[2,3-c] pyrazol-4-ones, 1-aryl-4,9-dihydro-3-methyl-1H-pyrazolo[3,4-b]quinolin-4- ones, and 1-aryl-1H-imidazo[4,5-b]quinoxalines.
Journal of medicinal chemistry 1995;38(8):1330-6.
1995: E Castagnino; A Salvatori; Stefano Corsano; P Tacchi; C Martini; Antonio Lucacchini
Effects of substituent size upon adenosine receptor A1/A2 affinity of some newly synthesised 8-cycloalkyl xanthines.
Drug design and discovery 1995;12(4):313-21.
1995: Giampaolo Primofiore; Federico Da Settimo; Anna Maria Marini; C La Motta; Claudia Martini; G Senatore; Antonio Lucacchini
N-(indol-3-ylglyoxylyl)amino acid ester derivatives. Synthesis and interaction properties at the benzodiazepine receptor.
Farmaco (Società chimica italiana : 1989) 1995;50(1):5-12.
1995: Giuliana Biagi; Irene Giorgi; Oreste Livi; Valerio Scartoni; Antonio Lucacchini; Claudia Martini; P Tacchi
Synthesis of new N(6)-substituted 2-phenyl-8-azaadenosines. Their affinity for adenosine A1 and A2 receptors. A comparison with the corresponding 2-phenyl-9-benzyl-8-azaadenines. VI.
Farmaco (Società chimica italiana : 1989) 1995;50(1):13-9.
1995: Maria Cristina Breschi; Claudia Martini; R Scatizzi; Renza Cristofani; Gino Giannaccini; Enrica Martinotti; Antonio Lucacchini
Benzodiazepine agonists reverse the effects of noise exposure on central benzodiazepine receptors and cardiac responsiveness.
Life sciences 1995;57(11):1131-40.
1995: Donatella Marazziti; Lionella Palego; B Dal Canto; Alessandro Rotondo; Massimo Pasqualetti ; G Gino; Antonio Lucacchini; H Ladinsky; Irma Nardi; Giovanni B Cassano
Presence of serotonin1A (5-HT1A) receptor mRNA without binding of [3H]-8-OH-DPAT in peripheral blood mononuclear cells.
Life sciences 1995;57(24):2197-203.
1994: Alessandro Rotondo; Gino Giannaccini; C Quattrone; Donatella Marazziti; Claudia Martini; Giovanni B Cassano; Antonio Lucacchini
Solubilization and characterization of [3H]imipramine and [3H]paroxetine binding sites from calf striatum.
Neurochemical research 1994;19(10):1295-300.
1994: Daniela Catarzi; L Cecchi; Vittoria Colotta; Fabrizio Melani; Guido Filacchioni; Claudia Martini; Laura Giusti; Antonio Lucacchini
Structure-activity relationships of 1,2,4-triazolo[1,5-a] quinoxalines and their 1-deaza analogues imidazo[1,2-a]quinoxalines at the benzodiazepine receptor.
Journal of medicinal chemistry 1994;37(18):2846-50.
1994: Laura Giusti; Letizia Trincavelli; Claudia Martini; Antonio Lucacchini
Characterization of peripheral-type benzodiazepine binding sites from rat and pig pancreas.
Biochemical pharmacology 1994;48(3):583-6.
1994: Antonio Da Settimo; Giampaolo Primofiore; Federico Da Settimo; F Simorini; P L Barili; G Senatore; Claudia Martini; Antonio Lucacchini
Synthesis and benzodiazepine receptor activity of some 4,5-dihydro-1H-pyrazolo[4,3-c][1,8]naphthyridine derivatives.
Drug design and discovery 1994;11(4):307-28.
1994: Giuliana Biagi; Irene Giorgi; Oreste Livi; Valerio Scartoni; Antonio Lucacchini; G Senatore; P L Barili
1,2,3-triazole[4,5-d]pyridazines. III--Synthesis of new 4-amino derivatives and their affinity toward adenosine receptors.
Farmaco (Società chimica italiana : 1989) 1994;49(5):357-62.
1994: Luana Perioli; Valeria Ambrogi; Giuliano Grandolini; L Giusti; Antonio Lucacchini; Claudia Martini
Studies on annelated 1,4-benzothiazines and 1,5-benzothiazepines. VIII-Synthesis and inhibition of benzodiazepine receptor binding of some derivatives of triazino[3,4-c]-1,4-benzothiazine and triazino[3,4-d]-1,5-benzothiazepine, two new heterocyclic ring systems.
Farmaco (Società chimica italiana : 1989) 1994;49(4):245-51.
1994: Giuliana Biagi; Irene Giorgi; Oreste Livi; Valerio Scartoni; Antonio Lucacchini; Claudia Martini; P Tacchi
N(6)-substituted 2-phenyl-9-benzyl-8-azaadenines. Affinity for adenosine A1 and A2 receptors. A comparison with 2-N-butyl analogous derivatives. V.
Farmaco (Società chimica italiana : 1989) 1994;49(3):187-91.
1994: Giuliana Biagi; Irene Giorgi; Oreste Livi; Valerio Scartoni; Antonio Lucacchini; Claudia Martini; P Tacchi
N(6)-substituted 2-N-butyl-9-benzyl-8-azaadenines. Affinity for adenosine A1 and A2 receptors. IV.
Farmaco (Società chimica italiana : 1989) 1994;49(3):183-6.
1994: Giuliana Biagi; Irene Giorgi; Oreste Livi; Valerio Scartoni; Antonio Lucacchini; Claudia Martini; P Tacchi
2-Aryl-8-azaadenosines: structure-activity relationships in the binding with A1 and A2 receptors. A comparison with the corresponding 9-benzyl-8-azaadenines. III.
Farmaco (Società chimica italiana : 1989) 1994;49(2):93-6.
1994: Daniela Catarzi; L Cecchi; Vittoria Colotta; Claudia Martini; Laura Giusti; Antonio Lucacchini; G Valle
Tricyclic heteroaromatic systems. 2-Phenyl-1,2,4-triazolo[1,5-c][1,3]benzoxazin-5-one: a novel benzodiazepine receptor ligand.
Farmaco (Società chimica italiana : 1989) 1994;49(2):89-92.
1994: R Polidori; P Tacchi; A Azzará; Claudia Martini; Antonio Lucacchini; M P Ferrara; Fabio Ambrogi
3H-NECA binding to polymorphonuclear membrane: effect of sera from patients with Hodgkin's disease.
Cancer investigation 1994;12(2):132-7.
1994: Donatella Marazziti; Alessandro Rotondo; Claudia Martini; Gino Giannaccini; Antonio Lucacchini; M L Pancioli-Guadagnucci; B I Diamond; R Borison; Giovanni B Cassano
Changes in peripheral benzodiazepine receptors in patients with panic disorder and obsessive-compulsive disorder.
Neuropsychobiology 1994;29(1):8-11.
1994: Claudia Martini; P Tacchi; L Bazzichi; marcello fiorini; F Bondi; M L Ciompi; Antonio Lucacchini
A2 adenosine receptors in neutrophils from healthy volunteers and patients with rheumatoid arthritis.
Advances in experimental medicine and biology 1994;370():407-10.
1994: Claudia Martini; Umberto Montali; Laura Giusti; marcello fiorini; Alessandra Falleni; Vittorio Gremigni; Antonio Lucacchini
A1 adenosine receptors in human neutrophils: electron microscope localization using a colloidal CHA-gold-albumin probe.
Advances in experimental medicine and biology 1994;370():401-5.
1993: Maria R Mazzoni; Claudia Martini; Antonio Lucacchini
Regulation of agonist binding to A2A adenosine receptors: effects of guanine nucleotides (GDP[S] and GTP[S]) and Mg2+ ion.
Biochimica et biophysica acta 1993;1220(1):76-84.
1993: Gino Giannaccini; Claudia Martini; Antonio Lucacchini; E Strettoi; M Piccolino
The peripheral-type benzodiazepine receptor ligands [3H]Ro 5-4864 and [3H]PK 11195 bind to the retina of rabbit, but not of turtle.
Journal of neurochemistry 1993;61(4):1263-9.
1993: Giuliana Biagi; Irene Giorgi; Oreste Livi; Antonio Lucacchini; Claudia Martini; Valerio Scartoni
Studies on specific inhibition of benzodiazepine receptor binding by some C-benzoyl-1,2,3-triazole derivatives.
Journal of pharmaceutical sciences 1993;82(9):893-6.
1993: Giuliana Biagi; M Ferretti; Irene Giorgi; Oreste Livi; Valerio Scartoni; Antonio Lucacchini
1,2,3-Triazole[4,5-d]pyridazines--I. Analogues of prostaglandin synthesis inhibitors.
Farmaco (Società chimica italiana : 1989) 1993;48(8):1159-65.
1993: Daniela Catarzi; L Cecchi; Vittoria Colotta; Fabrizio Melani; Guido Filacchioni; Claudia Martini; Laura Giusti; Antonio Lucacchini
Tricyclic heteroaromatic systems 1,2,4-triazolo[1,5-a]quinoxalines: synthesis and benzodiazepine receptor activity.
Farmaco (Società chimica italiana : 1989) 1993;48(8):1065-78.
1993: Vittoria Colotta; L Cecchi; Daniela Catarzi; G Conti; Guido Filacchioni; Claudia Martini; Laura Giusti; Antonio Lucacchini
Tricyclic heteroaromatic systems pyrazolo[1,5-a]quinoxalines: synthesis and benzodiazepine receptor activity.
Farmaco (Società chimica italiana : 1989) 1993;48(8):1051-63.
1993: Valeria Ambrogi; Giuliano Grandolini; Luana Perioli; L Giusti; Antonio Lucacchini; Claudia Martini
Studies on annelated 1,4-benzothiazines and 1,5-benzothiazepines. VII. Synthesis and inhibition of benzodiazepine receptor binding of some 4,5-dihydro-tetrazolo[5,1-d]-1,5-benzothiazepines and 5-phenyl-s-triazolo[3,4-d]-1,5-benzothiazepines.
Farmaco (Società chimica italiana : 1989) 1993;48(5):665-76.
1993: Daniela Catarzi; L Cecchi; Vittoria Colotta; G Conti; Fabrizio Melani; Guido Filacchioni; Claudia Martini; Laura Giusti; Antonio Lucacchini
Reaction of 1-aminophthalazines with alpha-halocarbonyl compounds: imidazo[2,1-a]phthalazines and their benzodiazepine receptor activities.
Farmaco (Società chimica italiana : 1989) 1993;48(4):447-57.
1993: Laura Giusti; M S Belfiore; Claudia Martini; Antonio Lucacchini
3 alpha-hydroxy-5 alpha-pregnan-20-one modulation of solubilized GABA/benzodiazepine receptor complex.
The Journal of steroid biochemistry and molecular biology 1993;45(4):309-14.
1993: Giuliana Biagi; Irene Giorgi; Oreste Livi; Valerio Scartoni; I Tonetti; Antonio Lucacchini
Xanthine oxidase (XO): relative configuration of complexes formed by the enzyme, 2- or 8-n-alkyl-hypoxanthines and 2-n-alkyl-8-azahypoxanthines. XII.
Farmaco (Società chimica italiana : 1989) 1993;48(3):357-74.
1993: Fabrizio Bruni; Annarella Costanzo; Silvia Selleri; Gabriella Guerrini; Laura Giusti; Claudia Martini; Antonio Lucacchini
Synthesis of 7-(2-dimethylaminovinyl) derivatives of pyrazolo[1,5-a] pyrimidines, as precursors of new tricyclic series. Binding studies of BDZ receptor.
Farmaco (Società chimica italiana : 1989) 1993;48(2):309-19.
1993: Antonio Da Settimo; Giampaolo Primofiore; Federico Da Settimo; Antonio Lucacchini; Claudia Martini; G Senatore
Benzodiazepine receptor affinity and interaction of new indole derivatives.
Farmaco (Società chimica italiana : 1989) 1993;48(2):285-95.
1993: Antonio Da Settimo; Giampaolo Primofiore; Federico Da Settimo; A Bianucci; Claudia Martini; G Senatore; Antonio Lucacchini
Synthesis and benzodiazepine receptor affinity of N-(indol-3-ylglyoxylyl)-dipeptide derivatives. Structural requirements for inverse agonist/antagonist receptor interactions.
Drug design and discovery 1993;10(3):199-211.
1993: Vittoria Colotta; L Cecchi; Daniela Catarzi; Fabrizio Melani; Guido Filacchioni; Claudia Martini; P Tacchi; Antonio Lucacchini
Novel adenosine receptor ligands: 1,3-disubstituted[1]benzopyrano[2,3-c]pyrazol-4-ones. Synthesis and structure-activity relationships.
Receptors & channels 1993;1(2):111-9.
1992: Vittoria Colotta; L Cecchi; Fabrizio Melani; Daniela Catarzi; Guido Filacchioni; Claudia Martini; Gino Giannaccini; M Tonelli; Antonio Lucacchini
Tricyclic heteroaromatic systems. Synthesis and benzodiazepine binding activity of 1-substituted-3-methyl- and 3-phenylpyrazolo[4,5-c]quinolin-4-ones.
Drug design and discovery 1992;8(4):325-39.
1992: A M Bianucci; Antonio Da Settimo; Federico Da Settimo; Giampaolo Primofiore; Claudia Martini; Gino Giannaccini; Antonio Lucacchini
Benzodiazepine receptor affinity and interaction of some N-(indol-3-ylglyoxylyl)amine derivatives.
Journal of medicinal chemistry 1992;35(12):2214-20.
1992: Giuliana Biagi; Oreste Livi; Antonio Lucacchini; Claudia Martini; Valerio Scartoni
Specific inhibition of binding to benzodiazepine receptors by 1,2,3-triazole derivatives.
Journal of pharmaceutical sciences 1992;81(6):543-5.
1992: B Macchia; Aldo Balsamo; Maria Cristina Breschi; A Lapucci; Antonio Lucacchini; F Macchia; Clementina Manera; Adriano Martinelli; Claudia Martini; Enrica Martinotti
Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alpha- and beta-adrenergic receptors.
Journal of medicinal chemistry 1992;35(6):1009-18.
1992: Gino Giannaccini; M Giacomelli; Claudia Martini; Antonio Lucacchini; M Piccolino
Binding of the benzodiazepine ligand [3H]-RO 15-1788 to membrane preparations of the rabbit and turtle retina.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1992;101(2):337-42.
1992: Laura Giusti; S Belfiore; Claudia Martini; Antonio Lucacchini
Sex steroid hormones and GABAA receptor complex modulation.
Advances in biochemical psychopharmacology 1992;47():133-41.
1991: Vittoria Colotta; L Cecchi; Fabrizio Melani; Guido Filacchioni; Claudia Martini; S Gelli; Antonio Lucacchini
Tricyclic heteroaromatic systems. Synthesis of 1,3 and 1,2 disubstituted [1]benzopyrano[4,3-b]pyrrol-4-ones and structure-activity relationships as benzodiazepine receptor ligands.
Farmaco (Società chimica italiana : 1989) 1991;46(10):1139-54.
1991: Vittoria Colotta; L Cecchi; Fabrizio Melani; Guido Filacchioni; Claudia Martini; S Gelli; Antonio Lucacchini
Tricyclic heteroaromatic systems: [1]benzopyrano-pyrazol-4-ones as benzodiazepine receptor ligands.
Journal of pharmaceutical sciences 1991;80(3):276-9.
1991: Claudia Martini; R Pacini; Antonio Lucacchini
Inactivation of [(35)S]t-butylbicyclophosphorothionate binding sites by the arginine reagent, 2,3-butanedione.
Neurochemistry international 1991;18(1):51-4.
1991: Ubaldo Bonuccelli; Angelo Nuti; Paolo Del Dotto; P Piccini; Claudia Martini; Gino Giannaccini; Antonio Lucacchini; A Muratorio
Platelet peripheral benzodiazepine receptors are decreased in Parkinson's disease.
Life sciences 1991;48(12):1185-90.
1991: Claudia Martini; S Di Sacco; P Tacchi; L Bazzichi; A Soletti; F Bondi; M L Ciompi; Antonio Lucacchini
A2 adenosine receptors in neutrophils from healthy volunteers and patients with rheumatic disease.
Advances in experimental medicine and biology 1991;309A():459-62.
1991: Claudia Martini; Umberto Montali; Laura Giusti; Gino Giannaccini; Alessandra Falleni; Vittorio Gremigni; Antonio Lucacchini
A ferritin-cyclohexyladenosine probe for electron microscope localization of A1 adenosine receptor.
Advances in experimental medicine and biology 1991;309A():451-4.
1990: Vittoria Colotta; L Cecchi; Fabrizio Melani; Guido Filacchioni; Claudia Martini; Gino Giannaccini; Antonio Lucacchini
Tricyclic heteroaromatic systems. [1]benzopyranopyrrol-4-ones and [1]benzopyrano-1,2,3-triazol-4-ones as benzodiazepine receptor ligands. Synthesis and structure-activity relationships.
Journal of medicinal chemistry 1990;33(9):2646-51.
1990: Giampaolo Primofiore; Anna Maria Marini; Federico Da Settimo; C Salvadori; Claudia Martini; Antonio Lucacchini; Gino Giannaccini
Specific inhibition of benzodiazepine receptor binding by some N-(2-methyl or 1,2-dimethylindol-3-ylglyoxylyl)amino acid derivatives.
Farmaco (Società chimica italiana : 1989) 1990;45(3):341-51.
1990: Maria R Mazzoni; Claudia Martini; Antonio Lucacchini
[(3)H]ouabain binding to ox brain membranes: Characterization of a high-affinity binding site.
Neurochemistry international 1990;16(2):193-7.
1990: Donatella Marazziti; S Michelini; Gino Giannaccini; Claudia Martini; Paolo Castrogiovanni; Giovanni B Cassano; Antonio Lucacchini
Stress-related changes of benzodiazepine binding inhibitory activity (B.B.I.A.) in humans.
Life sciences 1990;46(25):1833-6.
1990: Giuliana Biagi; Oreste Livi; G L Ramacciotti; Valerio Scartoni; L Bazzichi; Maria R Mazzoni; Antonio Lucacchini
Superoxide dismutase-like activity of 1,2,3-triazole derivatives.
Farmaco (Società chimica italiana : 1989) 1990;45(1):49-57.
1990: Donatella Marazziti; S Michelini; Claudia Martini; Gino Giannaccini; Giovanni B Cassano; Antonio Lucacchini
Benzodiazepine binding inhibitory activity (B.B.I.A.) in human plasma.
Advances in biochemical psychopharmacology 1990;46():213-20.
1989: Giampaolo Primofiore; Anna Maria Marini; Federico Da Settimo; Claudia Martini; A Bardellini; Gino Giannaccini; Antonio Lucacchini
Specific inhibition of benzodiazepine receptor binding by some N-(indol-3-ylglyoxylyl)amino acid derivatives: stereoselective interactions.
Journal of medicinal chemistry 1989;32(12):2514-8.
1989: Fabrizio Melani; L Cecchi; Vittoria Colotta; Guido Filacchioni; Claudia Martini; Gino Giannaccini; Antonio Lucacchini
Dipyrazolo[5,4-b:3',4'-d]pyridines. Synthesis, inhibition of benzodiazepine receptor binding and structure-activity relationships.
Farmaco (Società chimica italiana : 1989) 1989;44(6):585-94.
1989: L Cecchi; Vittoria Colotta; Fabrizio Melani; G Palazzino; Guido Filacchioni; Claudia Martini; Gino Giannaccini; Antonio Lucacchini
Synthesis of 1,5-diaryl-3-methyl-1H-pyrazolo[4,5-c]isoquinolines and studies of binding to specific peripheral benzodiazepine binding sites.
Journal of pharmaceutical sciences 1989;78(6):437-42.
1989: Vittoria Colotta; L Cecchi; Fabrizio Melani; G Palazzino; Guido Filacchioni; Claudia Martini; Gino Giannaccini; Antonio Lucacchini
Tricyclic heteroaromatic systems: synthesis, [3H]flunitrazepam brain membrane binding inhibition, and structure-activity relationships of 2,3-dihydro-2-aryl-4-R-[1]benzopyrano[4,3-c]pyrazole-3-ones.
Journal of pharmaceutical sciences 1989;78(3):239-42.
1989: Maria R Mazzoni; Gino Giannaccini; F Lena; Claudia Martini; L Bazzichi; M L Ciompi; Antonio Lucacchini
Urate binding globulin, interactions with immunoglobulins.
Advances in experimental medicine and biology 1989;253A():233-7.
1989: Claudia Martini; Gino Giannaccini; Antonio Lucacchini; L Bazzichi; A Soletti; M L Ciompi
A1 and A2 adenosine receptors in synovial cells from patients with rheumatic diseases.
Advances in experimental medicine and biology 1989;253B():429-33.
1989: Gino Giannaccini; S Gammarota; Claudia Martini; Antonio Lucacchini; M Piccolino
Binding of [3H] muscimol to the retina of rabbit and turtle.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1989;94(1):271-5.
1989: Donatella Marazziti; S Michelini; Claudia Martini; Gino Giannaccini; Antonio Lucacchini; Giovanni B Cassano
Further investigation on benzodiazepine binding inhibitory activity in patients with major depression or panic disorder and in healthy volunteers.
Neuropsychobiology 1989;21(1):14-6.
1988: Claudia Martini; W Marrucci; Antonio Lucacchini; Giuliana Biagi; Oreste Livi
Specific inhibition of benzodiazepine receptor binding by some 1,2,3-triazole derivatives.
Journal of pharmaceutical sciences 1988;77(11):977-80.
1988: B Macchia; Aldo Balsamo; A Lapucci; F Macchia; Clementina Manera; Susanna Nencetti; Maria Cristina Breschi; Antonio Lucacchini; Claudia Martini; Enrica Martinotti
An anomalous effect of N-isopropyl substitution in determining beta-adrenergic activity.
Drug design and delivery 1988;2(4):257-62.
1988: Vittoria Colotta; L Cecchi; Guido Filacchioni; Fabrizio Melani; G Palazzino; Claudia Martini; Gino Giannaccini; Antonio Lucacchini
Synthesis, binding studies, and structure-activity relationships of 1-aryl-and 2-aryl[1]benzopyranopyrazol-4-ones, central benzodiazepine receptor ligands.
Journal of medicinal chemistry 1988;31(1):1-3.
1987: G Palazzino; L Cecchi; Fabrizio Melani; Vittoria Colotta; Guido Filacchioni; Claudia Martini; Antonio Lucacchini
1,3-Diarylpyrazolo[4,5-c]- and -[5,4-c]quinolin-4-ones. 4. Synthesis and specific inhibition of benzodiazepine receptor binding.
Journal of medicinal chemistry 1987;30(10):1737-42.
1987: Claudia Martini; M Bertolini; Gino Giannaccini; Antonio Lucacchini
Barbiturate enhancement of [(3)H]flunitrazepam binding to purified benzodiazepine/gaba receptor from rat brain.
Neurochemistry international 1987;11(3):261-4.
1987: Aldo Balsamo; I Giorgi; A Lapucci; Antonio Lucacchini; B Macchia; F Macchia; Claudia Martini; A Rossi
3-[(2-ethoxyphenoxy)methyl]piperidine derivatives. Synthesis and antidepressant activity.
Journal of medicinal chemistry 1987;30(1):222-5.
1987: Donatella Marazziti; Pietro Pietrini; Claudia Martini; Gino Giannaccini; Giulio Perugi; Gian Franco Placidi; Giovanni B Cassano; Antonio Lucacchini
A 3H-flunitrazepam binding inhibitor is present in psychiatric patients' sera.
Neuropsychobiology 1987;18(2):74-6.
1986: Fabrizio Melani; L Cecchi; G Palazzino; Guido Filacchioni; Claudia Martini; E Pennacchi; Antonio Lucacchini
Pyrazolo[4,5-c]quinolines. 3. Synthesis, receptor binding, and 13C NMR study.
Journal of pharmaceutical sciences 1986;75(12):1175-9.
1986: Fabrizio Melani; L Cecchi; G Palazzino; Guido Filacchioni; Claudia Martini; E Pennacchi; Antonio Lucacchini
Pyrazolo[4,5-c]quinolines. 2. Synthesis and specific inhibition of benzodiazepine receptor binding.
Journal of medicinal chemistry 1986;29(2):291-5.
1985: L Cecchi; Fabrizio Melani; G Palazzino; Guido Filacchioni; Claudia Martini; E Pennacchi; Antonio Lucacchini
Synthesis and binding studies of 1-arylpyrazolo[4,5-c]- and 2-arylpyrazolo[4,3-c]quinolin-4-ones. I.
Il Farmaco; edizione scientifica 1985;40(7):509-16.
1985: Claudia Martini; T Gervasio; Antonio Lucacchini; Antonio Da Settimo; Giampaolo Primofiore; Anna Maria Marini
Specific inhibition of benzodiazepine receptor binding by some N-(indol-3-ylglyoxylyl)amino acid derivatives.
Journal of medicinal chemistry 1985;28(4):506-9.
1985: Giuliana Biagi; Oreste Livi; Antonio Da Settimo; Antonio Lucacchini; Maria R Mazzoni; P L Barili
4-(4-Phenylsubstituted)-1,2,3-triazolacetic acid derivatives in vitro inhibitors of prostaglandin synthesis.
Il Farmaco; edizione scientifica 1985;40(2):73-85.
1985: Claudia Martini; E Pennacchi; M G Poli; Antonio Lucacchini
Solubilization of adenosine A(1) binding sites from sheep cortex.
Neurochemistry international 1985;7(6):1017-20.
1982: Antonio Lucacchini; L Bazzichi; Giuliana Biagi; Oreste Livi; D Segnini
Effects of 6,9-disubstituted 8-azapurines on adenosine deaminase, guanine deaminase and xanthine oxidase.
The Italian journal of biochemistry 1982;31(3):153-62.