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Benedict Lucchesi

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Haoming Zhang; D Adam Lauver; Benedict R Lucchesi; Paul F Hollenberg
Formation, reactivity, and antiplatelet activity of mixed disulfide conjugates of clopidogrel.
D Adam Lauver; Nayiri M Kaissarian; Benedict R Lucchesi
Oral pretreatment with liposomal glutathione attenuates reperfusion injury in rabbit isolated hearts.
Jullia Y Lee; Francis S Markland; Benedict R Lucchesi
Hirudin and s18886 maintain luminal patency after thrombolysis with alfimeprase.

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All Publications

2013: Haoming Zhang; D Adam Lauver; Benedict R Lucchesi; Paul F Hollenberg
Formation, reactivity, and antiplatelet activity of mixed disulfide conjugates of clopidogrel.
Molecular pharmacology 2013;83(4):848-56.
2013: D Adam Lauver; Nayiri M Kaissarian; Benedict R Lucchesi
Oral pretreatment with liposomal glutathione attenuates reperfusion injury in rabbit isolated hearts.
Journal of cardiovascular pharmacology 2013;61(3):233-9.
2013: Jullia Y Lee; Francis S Markland; Benedict R Lucchesi
Hirudin and s18886 maintain luminal patency after thrombolysis with alfimeprase.
Journal of cardiovascular pharmacology 2013;61(2):152-9.
2011: Douglas L Miller; Chunyan Dou; Benedict R Lucchesi
Are ECG premature complexes induced by ultrasonic cavitation electrophysiological responses to irreversible cardiomyocyte injury?
Ultrasound in medicine & biology 2011;37(2):312-20.
2011: Jose Antonio Diaz; Angela E Hawley; Benedict R Lucchesi; Thomas W Wakefield; Shirley K Wrobleski; Daniel Durant Myers Jr
Electrolytic inferior vena cava model (EIM) of venous thrombosis.
Journal of visualized experiments : JoVE 2011;(53):e2737.
2010: Jose Antonio Diaz; Angela E Hawley; Christine M Alvarado; Alexandra M Berguer; Nichole K Baker; Shirley K Wrobleski; Thomas W Wakefield; Benedict R Lucchesi; Daniel Durant Myers Jr
Thrombogenesis with continuous blood flow in the inferior vena cava. A novel mouse model.
Thrombosis and haemostasis 2010;104(2):366-75.
2010: Gilad Rimon; Ranjinder Sidhu; D Adam Lauver; Jullia Young Lee; Narayan P Sharma; Chong Yuan; Ryan A Frieler; Raymond C Trievel; Benedict R Lucchesi; William L Smith
Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):28-33.
2009: Douglas L Miller; Chunyan Dou; Benedict R Lucchesi
Cardiac arrhythmia and injury induced in rats by burst and pulsed mode ultrasound with a gas body contrast agent.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2009;28(11):1519-26.
2008: Erin Anne Booth; RaShonda Renee Flint; Kathryn Louise Lucas; Andrea Kathleen Knittel; Benedict R Lucchesi
Estrogen protects the heart from ischemia-reperfusion injury via COX-2-derived PGI2.
Journal of cardiovascular pharmacology 2008;52(3):228-35.
2008: Marvin T Nieman; F Burke; M Warnock; Y Zhou; J Sweigart; A Chen; D Ricketts; Benedict R Lucchesi; Z Chen; E Di Cera; J Hilfinger; J S Kim; H I Mosberg; Alvin H Schmaier
Thrombostatin FM compounds: direct thrombin inhibitors - mechanism of action in vitro and in vivo.
Journal of thrombosis and haemostasis : JTH 2008;6(5):837-45.
2008: Marta Marchesi; Erin A Booth; Giuseppe Rossoni; Ricardo A García; Knut R Hill; Cesare R Sirtori; Charles L Bisgaier; Benedict R Lucchesi
Apolipoprotein A-IMilano/POPC complex attenuates post-ischemic ventricular dysfunction in the isolated rabbit heart.
Atherosclerosis 2008;197(2):572-8.
2008: Erin Anne Booth; Benedict R Lucchesi
Estrogen-mediated protection in myocardial ischemia-reperfusion injury.
Cardiovascular toxicology 2008;8(3):101-13.
2008: D Adam Lauver; Edward M Driscoll; Benedict R Lucchesi
Disodium disuccinate astaxanthin prevents carotid artery rethrombosis and ex vivo platelet activation.
Pharmacology 2008;82(1):67-73.
2008: Ting-Ting Hong; Jinbao Huang; Terrance D Barrett; Benedict R Lucchesi
Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis.
American journal of physiology. Heart and circulatory physiology 2008;294(1):H145-55.
2007: Erin Anne Booth; Benedict R Lucchesi
Medroxyprogesterone acetate prevents the cardioprotective and anti-inflammatory effects of 17beta-estradiol in an in vivo model of myocardial ischemia and reperfusion.
American journal of physiology. Heart and circulatory physiology 2007;293(3):H1408-15.
2007: Erin Anne Booth; Marta Marchesi; Andrea K Knittel; Edward J Kilbourne; Benedict R Lucchesi
The pathway-selective estrogen receptor ligand WAY-169916 reduces infarct size after myocardial ischemia and reperfusion by an estrogen receptor dependent mechanism.
Journal of cardiovascular pharmacology 2007;49(6):401-7.
2006: Ting-Ting Hong; Jinbao Huang; Edward M Driscoll; Benedict R Lucchesi
Preclinical evaluation of S18886 in an experimental model of coronary arterial thrombosis.
Journal of cardiovascular pharmacology 2006;48(5):239-48.
2006: D Adam Lauver; Benedict R Lucchesi
Sulodexide: a renewed interest in this glycosaminoglycan.
Cardiovascular drug reviews 2006;24(3-4):214-26.
2006: Douglas L Miller; Edward M Driscoll; Chunyan Dou; William F Armstrong; Benedict R Lucchesi
Microvascular permeabilization and cardiomyocyte injury provoked by myocardial contrast echocardiography in a canine model.
Journal of the American College of Cardiology 2006;47(7):1464-8.
2006: Ting-Ting Hong; Jinbao Huang; Benedict R Lucchesi
Effect of thrombolysis on myocardial injury: recombinant tissue plasminogen activator vs. alfimeprase.
American journal of physiology. Heart and circulatory physiology 2006;290(3):H959-67.
2006: James K Hennan; Edward M Driscoll; Terrance D Barrett; Peter S Fischbach; Benedict R Lucchesi
Effect of sodium/hydrogen exchange inhibition on myocardial infarct size after coronary artery thrombosis and thrombolysis.
Pharmacology 2006;78(1):27-37.
2006: Ting-Ting Hong; Cornelius L Van Gorp; Alan D Cardin; Benedict R Lucchesi
Intimatan (dermatan 4,6-O-disulfate) prevents rethrombosis after successful thrombolysis in the canine model of deep vessel wall injury.
Thrombosis research 2006;117(3):333-42.
2005: Erin Anne Booth; Nabeel R Obeid; Benedict R Lucchesi
Activation of estrogen receptor-alpha protects the in vivo rabbit heart from ischemia-reperfusion injury.
American journal of physiology. Heart and circulatory physiology 2005;289(5):H2039-47.
2005: Ting-Ting Hong; Jinbao Huang; Edward M Driscoll; Benedict R Lucchesi
The antithrombotic effect of melagatran in combination with clopidogrel and/or aspirin (carotid artery primary thrombosis study).
Journal of cardiovascular pharmacology 2005;46(4):526-33.
2005: D Adam Lauver; Samuel F Lockwood; Benedict R Lucchesi
Disodium Disuccinate Astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion.
The Journal of pharmacology and experimental therapeutics 2005;314(2):686-92.
2005: Manuel Rodríguez; Wei-Jun Cai; Sawa Kostin; Benedict R Lucchesi; Jutta Schaper
Ischemia depletes dystrophin and inhibits protein synthesis in the canine heart: mechanisms of myocardial ischemic injury.
Journal of molecular and cellular cardiology 2005;38(5):723-33.
2005: Ting-Ting Hong; Andrew J White; Benedict R Lucchesi
Dermatan disulfate (Intimatan) prevents complement-mediated myocardial injury in the human-plasma-perfused rabbit heart.
International immunopharmacology 2005;5(2):381-91.
2005: D Adam Lauver; Erin Anne Booth; Andrew J White; Enrique Poradosu; Benedict R Lucchesi
Sulodexide attenuates myocardial ischemia/reperfusion injury and the deposition of C-reactive protein in areas of infarction without affecting hemostasis.
The Journal of pharmacology and experimental therapeutics 2005;312(2):794-800.
2004: Marta Marchesi; Erin Anne Booth; Treasa Davis; Charles L Bisgaier; Benedict R Lucchesi
Apolipoprotein A-IMilano and 1-palmitoyl-2-oleoyl phosphatidylcholine complex (ETC-216) protects the in vivo rabbit heart from regional ischemia-reperfusion injury.
The Journal of pharmacology and experimental therapeutics 2004;311(3):1023-31.
2004: Marvin T Nieman; Mark Warnock; Ahmed Hasan; Fakhri Mahdi; Benedict R Lucchesi; Nancy J Brown; Laine J Murphey; Alvin H Schmaier
The preparation and characterization of novel peptide antagonists to thrombin and factor VIIa and activation of protease-activated receptor 1.
The Journal of pharmacology and experimental therapeutics 2004;311(2):492-501.
2004: Peter S Fischbach; Andrew White; Terrance D Barrett; Benedict R Lucchesi
Risk of ventricular proarrhythmia with selective opening of the myocardial sarcolemmal versus mitochondrial ATP-gated potassium channel.
The Journal of pharmacology and experimental therapeutics 2004;309(2):554-9.
2003: Erin Anne Booth; Marta Marchesi; Edward J Kilbourne; Benedict R Lucchesi
17Beta-estradiol as a receptor-mediated cardioprotective agent.
The Journal of pharmacology and experimental therapeutics 2003;307(1):395-401.
2003: Ting-Ting Hong; Edward M Driscoll; Andrew J White; Ardaman Sherigill; Thierry A Giboulot; Benedict R Lucchesi
Glycoprotein IIb/IIIa receptor antagonist (2S)-2-[(2-Naphthyl-sulfonyl)amino]-3-[[2-([4-(4-piperidinyl)-2-[2-(4-piperidinyl)ethyl] butanoyl]amino)acetyl]amino]propanoic acid dihydrochloride (CRL42796), in combination with aspirin and/or enoxaparin, prevents coronary artery rethrombosis after successful thrombolytic treatment by recombinant tissue plasminogen activator.
The Journal of pharmacology and experimental therapeutics 2003;306(2):616-23.
2003: James K Hennan; David E Willens; Edward M Driscoll; Ting-Ting Hong; Thierry A Giboulot; Benedict R Lucchesi
Prevention of carotid artery thrombosis after oral administration of the glycoprotein IIb/IIIa antagonist CRL42796.
Journal of cardiovascular pharmacology 2003;42(1):71-7.
2003: Peter S Fischbach; Terrance D Barrett; Nathan J Reed; Benedict R Lucchesi
SNC-80-induced preconditioning: selective activation of the mitochondrial adenosine triphosphate-gated potassium channel.
Journal of cardiovascular pharmacology 2003;41(5):744-50.
2002: Terrance D Barrett; James K Hennan; Rory M Marks; Benedict R Lucchesi
C-reactive-protein-associated increase in myocardial infarct size after ischemia/reperfusion.
The Journal of pharmacology and experimental therapeutics 2002;303(3):1007-13.
2002: James K Hennan; Ting-Ting Hong; David E Willens; Edward M Driscoll; Thierry A Giboulot; Benedict R Lucchesi
Prevention of experimental carotid and coronary artery thrombosis by the glycoprotein IIb/IIIa receptor antagonist CRL42796.
British journal of pharmacology 2002;136(6):927-37.
2002: James K Hennan; Ting-Ting Hong; Ardamanpal K Shergill; Edward M Driscoll; Alan D Cardin; Benedict R Lucchesi
Intimatan prevents arterial and venous thrombosis in a canine model of deep vessel wall injury.
The Journal of pharmacology and experimental therapeutics 2002;301(3):1151-6.
2002: Manuel Rodríguez; Benedict R Lucchesi; Jutta Schaper
Apoptosis in myocardial infarction.
Annals of medicine 2002;34(6):470-9.
2001: A A Hasa; Alvin H Schmaier; Mark Warnock; Daniel Normolle; Edward M Driscoll; Benedict R Lucchesi; Steven W Werns
Thrombostatin inhibits cyclic flow variations in stenosed canine coronary arteries.
Thrombosis and haemostasis 2001;86(5):1296-304.
2001: Peter S Fischbach; Terrance D Barrett; R Goyal; B C Tran; Zaffer Syed; James K Hennan; Benedict R Lucchesi
Conversion of atrial fibrillation by the experimental antiarrhythmic drug tedisamil in two canine models.
Journal of cardiovascular electrophysiology 2001;12(10):1138-44.
2001: James K Hennan; Jinbao Huang; Terrance D Barrett; Edward M Driscoll; David E Willens; A M Park; Leslie J Crofford; Benedict R Lucchesi
Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries.
Circulation 2001;104(7):820-5.
2001: Benedict R Lucchesi
2001 Torald Sollmann Award lecture. Looking toward the future, using lessons from the past.
The Journal of pharmacology and experimental therapeutics 2001;297(3):829-36.
2001: Terrance D Barrett; James K Hennan; Peter S Fischbach; B P O'Neill; E M Driscoll Jr; Benedict R Lucchesi
Tedisamil and dofetilide-induced torsades de pointes, rate and potassium dependence.
British journal of pharmacology 2001;132(7):1493-500.
2001: M B Patel; Kenneth S Kilgore; Girolamo A Ortolano; C L Gryboski; Mansoor A Qureshi; Pamela A Marcovitz; Keith B Naylor; James L Park; Barry Wenz; Nicolas Gikakis; R J Freedman; Benedict R Lucchesi; William W O'Neill
Conditioned blood reperfusion during angioplasty (CoBRA) treatment of acute myocardial infarction.
Perfusion 2001;16 Suppl():39-49.
2001: Jinbao Huang; V M Feldbaum; Benedict R Lucchesi; Steven W Werns
Effects of adenosine on thrombosis and thrombolysis in a canine experimental preparation.
Pharmacology 2001;63(3):166-74.
2000: Jinbao Huang; Edward M Driscoll; M L Gonzales; A M Park; Benedict R Lucchesi
Prevention of arterial thrombosis by intravenously administered platelet P2T receptor antagonist AR-C69931MX in a canine model.
The Journal of pharmacology and experimental therapeutics 2000;295(2):492-9.
2000: EJ Tanhehco; H Lee; Benedict R Lucchesi
Sublytic complement attack reduces infarct size in rabbit isolated hearts: evidence for C5a-mediated cardioprotection.
Immunopharmacology 2000;49(3):391-9.
2000: EJ Tanhehco; Koji Yasojima; Patrick L McGeer; Edith G McGeer; Benedict R Lucchesi
Preconditioning reduces myocardial complement gene expression in vivo.
American journal of physiology. Heart and circulatory physiology 2000;279(3):H1157-65.
2000: EJ Tanhehco; Koji Yasojima; Patrick L McGeer; RA Washington; Benedict R Lucchesi
Free radicals upregulate complement expression in rabbit isolated heart.
American journal of physiology. Heart and circulatory physiology 2000;279(1):H195-201.
2000: SS Rebello; H S Blank; Benedict R Lucchesi
Antithrombotic efficacy of single subcutaneous administration of a recombinant nematode anticoagulant peptide (rNAP5) in a canine model of coronary artery thrombolysis.
Thrombosis research 2000;98(6):531-40.
2000: Benedict R Lucchesi; EJ Tanhehco
Therapeutic potential of complement inhibitors in myocardial ischaemia.
Expert opinion on investigational drugs 2000;9(5):975-91.
2000: K S Kilgore; Benedict R Lucchesi
Neutrophils and altered myocardial function.
American heart journal 2000;139(1 Pt 1):32-4.
2000: EJ Tanhehco; Koji Yasojima; Patrick L McGeer; Benedict R Lucchesi
Acute cocaine exposure up-regulates complement expression in rabbit heart.
The Journal of pharmacology and experimental therapeutics 2000;292(1):201-8.
2000: SS Rebello; Jinbao Huang; JD Faul; Benedict R Lucchesi
Role of extracellular ionized calcium in the in vitro assessment of GPIIb/IIIa receptor antagonists.
Journal of thrombosis and thrombolysis 2000;9(1):23-8.
1999: EJ Tanhehco; Koji Yasojima; Patrick L McGeer; RA Washington; Kenneth S Kilgore; Jonathon W Homeister; Benedict R Lucchesi
Preconditioning reduces tissue complement gene expression in the rabbit isolated heart.
The American journal of physiology 1999;277(6 Pt 2):H2373-80.
1999: Gail M Annich; T White; D Damm; Yunde Zhao; Fakhri Mahdi; Juergen P Meinhardt; SS Rebello; Benedict R Lucchesi; robert bartlett; Alvin H Schmaier
Recombinant Kunitz protease inhibitory domain of the amyloid beta-protein precursor as an anticoagulant in venovenous extracorporeal circulation in rabbits.
Thrombosis and haemostasis 1999;82(5):1474-81.
1999: James L Park; Benedict R Lucchesi
Mechanisms of myocardial reperfusion injury.
The Annals of thoracic surgery 1999;68(5):1905-12.
1999: Ahmed Hasan; SS Rebello; E Smith; Sujata Srikanth; Steven W Werns; Edward M Driscoll; JD Faul; Dean E Brenner; Daniel Normolle; Benedict R Lucchesi; Alvin H Schmaier
Thrombostatin inhibits induced canine coronary thrombosis.
Thrombosis and haemostasis 1999;82(3):1182-7.
1999: Kenneth S Kilgore; EJ Tanhehco; Keith B Naylor; Benedict R Lucchesi
Ex vivo reversal of heparin-mediated cardioprotection by heparinase after ischemia and reperfusion.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1041-7.
1999: CF Schwartz; Kenneth S Kilgore; Jonathon W Homeister; B A Levy; Benedict R Lucchesi; Steven F Bolling
Increased rat cardiac allograft survival by the glycosaminoglycan pentosan polysulfate.
The Journal of surgical research 1999;86(1):24-8.
1999: EJ Tanhehco; Kenneth S Kilgore; D A Liff; K L Murphy; M S Fung; W N Sun; C Sun; Benedict R Lucchesi
The anti-factor D antibody, MAb 166-32, inhibits the alternative pathway of the human complement system.
Transplantation proceedings 1999;31(5):2168-71.
1999: Peter S Fischbach; Peter V Johnston; G S Friedrichs; Benedict R Lucchesi
Tedisamil in a chronic canine model of atrial flutter.
Journal of cardiovascular pharmacology 1999;34(2):212-8.
1999: EJ Tanhehco; Kenneth S Kilgore; Keith B Naylor; James L Park; Erin Anne Booth; Benedict R Lucchesi
Reduction of myocardial infarct size after ischemia and reperfusion by the glycosaminoglycan pentosan polysulfate.
Journal of cardiovascular pharmacology 1999;34(1):153-61.
1999: SS Rebello; Jinbao Huang; K Saito; Jorge F Saucedo; Eric R Bates; Benedict R Lucchesi
Effect of time of 7E3 administration on rt-PA-induced reperfusion: study in a canine model of thrombus-based occlusion-reperfusion.
European journal of pharmacology 1999;374(3):399-410.
1999: Jinbao Huang; SS Rebello; JD Faul; Benedict R Lucchesi
Correlation between the in vivo efficacy of GPIIb/IIIa receptor antagonists (m7E3, MK-383 and DMP-728) and ex vivo platelet inhibition.
Pharmacology 1999;58(5):252-64.
1999: James L Park; Kenneth S Kilgore; Keith B Naylor; Erin Anne Booth; K L Murphy; Benedict R Lucchesi
N-Acetylheparin pretreatment reduces infarct size in the rabbit.
Pharmacology 1999;58(3):120-31.
1999: Jinbao Huang; SS Rebello; L A Rosenberg; M Kaneko; T Sakurama; Benedict R Lucchesi
Temporary and partial inhibition of platelets by SM-20302 prevents coronary artery thrombosis in a chronic canine model.
European journal of pharmacology 1999;366(2-3):203-13.
1998: SS Rebello; Jinbao Huang; W J Shiu; K Saito; M Kaneko; Y Saitoh; Benedict R Lucchesi
Pharmacokinetics and pharmacodynamics of SM-20302, a GPIIb/IIIa receptor antagonist, in anesthetized dogs.
Journal of cardiovascular pharmacology 1998;32(3):485-94.
1998: S C Black; Edward M Driscoll; Benedict R Lucchesi
Effect of ramiprilat or captopril on myocardial infarct size: assessment in canine models of ischemia alone and ischemia with reperfusion.
Pharmacology 1998;57(1):35-46.
1998: Koji Yasojima; K S Kilgore; RA Washington; Benedict R Lucchesi; Patrick L McGeer
Complement gene expression by rabbit heart: upregulation by ischemia and reperfusion.
Circulation research 1998;82(11):1224-30.
1998: SS Rebello; Jinbao Huang; K Saito; Benedict R Lucchesi
In vivo efficacy of SM-20302, a GP IIb/IIIa receptor antagonist, correlates with ex vivo platelet inhibition in heparinized blood but not in citrated blood.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(6):954-60.
1998: Kenneth S Kilgore; Keith B Naylor; EJ Tanhehco; James L Park; Erin Anne Booth; RA Washington; Benedict R Lucchesi
The semisynthetic polysaccharide pentosan polysulfate prevents complement-mediated myocardial injury in the rabbit perfused heart.
The Journal of pharmacology and experimental therapeutics 1998;285(3):987-94.
1998: Kenneth S Kilgore; James L Park; EJ Tanhehco; Erin Anne Booth; Rory M Marks; Benedict R Lucchesi
Attenuation of interleukin-8 expression in C6-deficient rabbits after myocardial ischemia/reperfusion.
Journal of molecular and cellular cardiology 1998;30(1):75-85.
1998: G S Friedrichs; J N Abreu; Edward M Driscoll; J Borlak; Benedict R Lucchesi
Antifibrillatory efficacy of long-term tedisamil administration in a postinfarcted canine model of ischemic ventricular fibrillation.
Journal of cardiovascular pharmacology 1998;31(1):56-66.
1998: Kenneth S Kilgore; EJ Tanhehco; James L Park; Keith B Naylor; M Brownell Anderson; Benedict R Lucchesi
Reduction of myocardial infarct size in vivo by carbohydrate-based glycomimetics.
The Journal of pharmacology and experimental therapeutics 1998;284(1):427-35.
1997: Benedict R Lucchesi; Kenneth S Kilgore
Complement inhibitors in myocardial ischemia/reperfusion injury.
Immunopharmacology 1997;38(1-2):27-42.
1997: James L Park; EJ Tanhehco; Kenneth S Kilgore; M R Gralinski; Benedict R Lucchesi
Reviparin-sodium prevents complement-mediated myocardial injury in the isolated rabbit heart.
Journal of cardiovascular pharmacology 1997;30(5):658-66.
1997: SS Rebello; H S Blank; William E Rote; George P Vlasuk; Benedict R Lucchesi
Antithrombotic efficacy of a recombinant nematode anticoagulant peptide (rNAP5) in canine models of thrombosis after single subcutaneous administration.
The Journal of pharmacology and experimental therapeutics 1997;283(1):91-9.
1997: SS Rebello; Edward M Driscoll; Benedict R Lucchesi
TP-9201, a glycoprotein IIb/IIIa platelet receptor antagonist, prevents rethrombosis after successful arterial thrombolysis in the dog.
Stroke; a journal of cerebral circulation 1997;28(9):1789-96.
1997: M R Gralinski; James L Park; M A Ozeck; B C Wiater; Benedict R Lucchesi
LU 51198, a highly sulfated, low-molecular-weight heparin derivative, prevents complement-mediated myocardial injury in the perfused rabbit heart.
The Journal of pharmacology and experimental therapeutics 1997;282(2):554-60.
1997: S A Mousa; D X Mu; Benedict R Lucchesi
Prevention of carotid artery thrombosis by oral platelet GPIIb/IIIa antagonist in dogs.
Stroke; a journal of cerebral circulation 1997;28(4):830-5; discussion 835-6.
1997: SS Rebello; B V Miller; G C Basler; Benedict R Lucchesi
CVS-1123, a direct thrombin inhibitor, prevents occlusive arterial and venous thrombosis in a canine model of vascular injury.
Journal of cardiovascular pharmacology 1997;29(2):240-9.
1996: G R Cousins; G S Friedrichs; Y Sudo; SS Rebello; W E Rote; G P Vlasuk; T G Nolan; C Mendoza; Benedict R Lucchesi
Orally effective CVS-1123 prevents coronary artery thrombosis in the conscious dog.
Circulation 1996;94(7):1705-12.
1996: M R Gralinski; B C Wiater; A N Assenmacher; Benedict R Lucchesi
Selective inhibition of the alternative complement pathway by sCR1[desLHR-A] protects the rabbit isolated heart from human complement-mediated damage.
Immunopharmacology 1996;34(2-3):79-88.
1996: M R Gralinski; S C Black; LF Stancato; Kenneth S Kilgore; P A Campau; James L Park; M J Ozeck; William B Pratt; Benedict R Lucchesi
Heat stress protects the perfused rabbit heart from complement-mediated injury.
The American journal of physiology 1996;271(2 Pt 2):H571-8.
1996: G S Friedrichs; J N Abreu; S C Black; Liguo Chi; Benedict R Lucchesi
5-hydroxydecanoate fails to attenuate ventricular fibrillation in a conscious canine model of sudden cardiac death.
European journal of pharmacology 1996;306(1-3):99-106.
1996: Y Sudo; Benedict R Lucchesi
Antithrombotic effect of GYKI-14766 in a canine model of arterial and venous rethrombosis: a comparison with heparin.
Journal of cardiovascular pharmacology 1996;27(4):545-55.
1996: Liguo Chi; James L Park; G S Friedrichs; Y A Banglawala; M A Perez; EJ Tanhehco; Benedict R Lucchesi
Effects of tedisamil (KC-8857) on cardiac electrophysiology and ventricular fibrillation in the rabbit isolated heart.
British journal of pharmacology 1996;117(6):1261-9.
1996: Shaker A Mousa; W F DeGrado; D X Mu; R P Kapil; Benedict R Lucchesi; Thomas M Reilly
Oral antiplatelet, antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa antagonist.
Circulation 1996;93(3):537-43.
1995: Y Sudo; Kenneth S Kilgore; Benedict R Lucchesi
Monoclonal antibody [7E3 F(ab')2] prevents arterial but not venous rethrombosis.
Journal of cardiovascular pharmacology 1995;26(2):241-50.
1995: R Virkhaus; Benedict R Lucchesi; P J Simpson; R J Shebuski
The role of adhesion molecules in cardiovascular pharmacology: meeting review.
The Journal of pharmacology and experimental therapeutics 1995;273(2):569-75.
1995: S C Black; M R Gralinski; G S Friedrichs; Kenneth S Kilgore; Edward M Driscoll; Benedict R Lucchesi
Cardioprotective effects of heparin or N-acetylheparin in an in vivo model of myocardial ischaemic and reperfusion injury.
Cardiovascular research 1995;29(5):629-36.
1995: G S Friedrichs; Liguo Chi; M R Gralinski; S C Black; G C Basler; D X Mu; S R Pewitt; C R Johnson; Benedict R Lucchesi
MS-551 protects against ventricular fibrillation in a chronic canine model of sudden cardiac death.
Journal of cardiovascular pharmacology 1995;25(2):314-23.
1995: M Minami; Edward M Driscoll; P J Simpson; P T Hoff; Benedict R Lucchesi
Effects of BMY21190, an inhibitor of cAMP phosphodiesterase, on infarct size and myeloperoxidase activity in the ischemic myocardium of a canine occlusion-reperfusion model.
Pharmacology 1995;50(1):24-33.
1994: S C Black; M R Gralinski; J G McCormack; Edward M Driscoll; Benedict R Lucchesi
Effect of ranolazine on infarct size in a canine model of regional myocardial ischemia/reperfusion.
Journal of cardiovascular pharmacology 1994;24(6):921-8.
1994: F S Markland; G S Friedrichs; S R Pewitt; Benedict R Lucchesi
Thrombolytic effects of recombinant fibrolase or APSAC in a canine model of carotid artery thrombosis.
Circulation 1994;90(5):2448-56.
1994: Liguo Chi; G S Friedrichs; J Y Oh; A L Green; Benedict R Lucchesi
Effect of Ado A1- and A2-receptor activation on ventricular fibrillation during hypoxia-reoxygenation.
The American journal of physiology 1994;267(4 Pt 2):H1447-54.
1994: G S Friedrichs; Kenneth S Kilgore; P J Manley; M R Gralinski; Benedict R Lucchesi
Effects of heparin and N-acetyl heparin on ischemia/reperfusion-induced alterations in myocardial function in the rabbit isolated heart.
Circulation research 1994;75(4):701-10.
1994: S C Black; C S Schasteen; R H Weiss; Dennis P Riley; Edward M Driscoll; Benedict R Lucchesi
Inhibition of in vivo myocardial ischemic and reperfusion injury by a synthetic manganese-based superoxide dismutase mimetic.
The Journal of pharmacology and experimental therapeutics 1994;270(3):1208-15.
1994: G S Friedrichs; Liguo Chi; A L Green; Benedict R Lucchesi
Antifibrillatory effects of clofilium in the rabbit isolated heart.
British journal of pharmacology 1994;113(1):209-15.
1994: M R Gralinski; S C Black; Kenneth S Kilgore; A Y Chou; J G McCormack; Benedict R Lucchesi
Cardioprotective effects of ranolazine (RS-43285) in the isolated perfused rabbit heart.
Cardiovascular research 1994;28(8):1231-7.
1994: Kenneth S Kilgore; G S Friedrichs; C R Johnson; C S Schasteen; Dennis P Riley; R H Weiss; U Ryan; Benedict R Lucchesi
Protective effects of the SOD-mimetic SC-52608 against ischemia/reperfusion damage in the rabbit isolated heart.
Journal of molecular and cellular cardiology 1994;26(8):995-1006.
1994: W E Rote; M A Nedelman; D X Mu; P J Manley; H Weisman; M R Cunningham; Benedict R Lucchesi
Chimeric 7E3 prevents carotid artery thrombosis in cynomolgus monkeys.
Stroke; a journal of cerebral circulation 1994;25(6):1223-32; discussion 1233.
1994: S C Black; Benedict R Lucchesi
Potassium channel openers are likely to be proarrhythmic in the diseased human heart.
Cardiovascular research 1994;28(6):923-4; discussion 926-9.
1994: Kenneth S Kilgore; G S Friedrichs; Jonathon W Homeister; Benedict R Lucchesi
The complement system in myocardial ischaemia/reperfusion injury.
Cardiovascular research 1994;28(4):437-44.
1994: Steven W Werns; W E Rote; J H Davis; T Guevara; Benedict R Lucchesi
Nitroglycerin inhibits experimental thrombosis and reocclusion after thrombolysis.
American heart journal 1994;127(4 Pt 1):727-37.
1994: Daniel T Eitzman; L Chi; L Saggin; R S Schwartz; Benedict R Lucchesi; William P Fay
Heparin neutralization by platelet-rich thrombi. Role of platelet factor 4.
Circulation 1994;89(4):1523-9.
1994: W E Rote; J H Davis; S A Mousa; T M Reilly; Benedict R Lucchesi
Antithrombotic effects of DMP 728, a platelet GPIIb/IIIa receptor antagonist, in a canine model of arterial thrombosis.
Journal of cardiovascular pharmacology 1994;23(4):681-9.
1994: Benedict R Lucchesi
Complement, neutrophils and free radicals: mediators of reperfusion injury.
Arzneimittel-Forschung 1994;44(3A):420-32.
1994: W E Rote; D X Mu; Eric R Bates; M A Nedelman; Benedict R Lucchesi
Prevention of rethrombosis after coronary thrombolysis in a chronic canine model. II. Adjunctive therapy with r-hirudin.
Journal of cardiovascular pharmacology 1994;23(2):203-11.
1994: W E Rote; D X Mu; Eric R Bates; M A Nedelman; Benedict R Lucchesi
Prevention of rethrombosis after coronary thrombolysis in a chronic canine model. I. Adjunctive therapy with monoclonal antibody 7E3 F(ab')2 fragment.
Journal of cardiovascular pharmacology 1994;23(2):194-202.
1994: Kenneth S Kilgore; Jonathon W Homeister; P S Satoh; Benedict R Lucchesi
Sulfhydryl compounds, captopril, and MPG inhibit complement-mediated myocardial injury.
The American journal of physiology 1994;266(1 Pt 2):H28-35.
1994: Mohit Trikha; W E Rote; P J Manley; Benedict R Lucchesi; Francis S Markland
Purification and characterization of platelet aggregation inhibitors from snake venoms.
Thrombosis research 1994;73(1):39-52.
1994: L Chi; S C Black; G S Friedrichs; Benedict R Lucchesi
ATP sensitive potassium channels and ischemic heart disease.
Cardiovascular research 1994;28(1):136-7.
1994: Jonathon W Homeister; Benedict R Lucchesi
Complement activation and inhibition in myocardial ischemia and reperfusion injury.
Annual review of pharmacology and toxicology 1994;34():17-40.
1994: G S Friedrichs; Liguo Chi; S C Black; P J Manley; Benedict R Lucchesi
Antiarrhythmic agent, MS-551, protects against pinacidil + hypoxia-induced ventricular fibrillation in Langendorff-perfused rabbit isolated heart.
Journal of cardiovascular pharmacology 1994;23(1):120-6.
1993: Benedict R Lucchesi
Complement activation, neutrophils, and oxygen radicals in reperfusion injury.
Stroke; a journal of cerebral circulation 1993;24(12 Suppl):I41-7; discussion I38-40.
1993: S C Black; S O Fagbemi; Liguo Chi; G S Friedrichs; Benedict R Lucchesi
Phorbol ester-induced ventricular fibrillation in the Langendorff-perfused rabbit heart: antagonism by staurosporine and glibenclamide.
Journal of molecular and cellular cardiology 1993;25(12):1427-38.
1993: S C Black; J L Butterfield; Benedict R Lucchesi
Protection against programmed electrical stimulation-induced ventricular tachycardia and sudden cardiac death by NE-10064, a class III antiarrhythmic drug.
Journal of cardiovascular pharmacology 1993;22(6):810-8.
1993: Benedict R Lucchesi; Liguo Chi; G S Friedrichs; S C Black; A C Uprichard
Antiarrhythmic versus antifibrillatory actions: inference from experimental studies.
The American journal of cardiology 1993;72(16):25F-44F.
1993: S C Black; G S Friedrichs; Benedict R Lucchesi
The autonomic nervous system, myocardial infarct size and ventricular fibrillation.
Journal of molecular and cellular cardiology 1993;25(11):1291-2.
1993: A C Uprichard; Liguo Chi; Benedict R Lucchesi
Functional consequence of big endothelin conversion: demonstration with isolated neutrophils but not in a postinfarction model.
Pharmacology 1993;47(5):277-85.
1993: W E Rote; D X Mu; R A Roncinske; A L Frelinger; Benedict R Lucchesi
Prevention of experimental carotid artery thrombosis by applaggin.
The Journal of pharmacology and experimental therapeutics 1993;267(2):809-14.
1993: Kenneth S Kilgore; Benedict R Lucchesi
Reperfusion injury after myocardial infarction: the role of free radicals and the inflammatory response.
Clinical biochemistry 1993;26(5):359-70.
1993: M Minami; Edward M Driscoll; Benedict R Lucchesi
Antithrombotic effects of BMY21190, an inhibitor of cAMP phosphodiesterase, in a canine model of coronary artery thrombosis.
Japanese circulation journal 1993;57(10):979-92.
1993: G S Friedrichs; Liguo Chi; S C Black; P J Manley; J Y Oh; Benedict R Lucchesi
Antifibrillatory effects of ibutilide in the rabbit isolated heart: mediation via ATP-dependent potassium channels.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1348-54.
1993: J F Tschopp; Edward M Driscoll; D X Mu; S C Black; M D Pierschbacher; Benedict R Lucchesi
Inhibition of coronary artery reocclusion after thrombolysis with an RGD-containing peptide with no significant effect on bleeding time.
Coronary artery disease 1993;4(9):809-17.
1993: Kenneth S Kilgore; Benedict R Lucchesi
Effect of hypoxia and reoxygenation on the isolated rabbit heart determined by monoclonal antimyosin antibody uptake.
Cardiovascular research 1993;27(7):1260-7.
1993: W E Rote; D X Mu; Benedict R Lucchesi
Thromboxane antagonism in experimental canine carotid artery thrombosis.
Stroke; a journal of cerebral circulation 1993;24(6):820-7; discussion 827-8.
1993: S O Fagbemi; Liguo Chi; Benedict R Lucchesi
Antifibrillatory and profibrillatory actions of selected class I antiarrhythmic agents.
Journal of cardiovascular pharmacology 1993;21(5):709-19.
1993: W E Rote; Steven W Werns; J H Davis; L P Feigen; Kenneth S Kilgore; Benedict R Lucchesi
Platelet GPIIb/IIIa receptor inhibition by SC-49992 prevents thrombosis and rethrombosis in the canine carotid artery.
Cardiovascular research 1993;27(3):500-7.
1993: S C Black; Benedict R Lucchesi
Heat shock proteins and the ischemic heart. An endogenous protective mechanism.
Circulation 1993;87(3):1048-51.
1993: J K Mickelson; P T Hoff; Jonathon W Homeister; Joseph C Fantone III; Benedict R Lucchesi
High dose intravenous aspirin, not low dose intravenous or oral aspirin, inhibits thrombus formation and stabilizes blood flow in experimental coronary vascular injury.
Journal of the American College of Cardiology 1993;21(2):502-10.
1993: Jonathon W Homeister; P S Satoh; Kenneth S Kilgore; Benedict R Lucchesi
Soluble complement receptor type 1 prevents human complement-mediated damage of the rabbit isolated heart.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(3):1055-64.
1993: Liguo Chi; S C Black; P I Kuo; S O Fagbemi; Benedict R Lucchesi
Actions of pinacidil at a reduced potassium concentration: a direct cardiac effect possibly involving the ATP-dependent potassium channel.
Journal of cardiovascular pharmacology 1993;21(2):179-90.
1992: S C Black; Edward M Driscoll; Benedict R Lucchesi
Inhibition of platelet-activating factor fails to limit ischemia and reperfusion-induced myocardial damage.
Journal of cardiovascular pharmacology 1992;20(6):997-1005.
1992: Steven W Werns; Joseph C Fantone III; Alejandra C Ventura; Benedict R Lucchesi
Myocardial glutathione depletion impairs recovery of isolated blood-perfused hearts after global ischaemia.
Journal of molecular and cellular cardiology 1992;24(11):1215-20.
1992: Jonathon W Homeister; P Satoh; Benedict R Lucchesi
Effects of complement activation in the isolated heart. Role of the terminal complement components.
Circulation research 1992;71(2):303-19.
1991: W A Schumacher; Joseph C Fantone III; Steven Kunkel; R Clinton Webb; Benedict R Lucchesi
The anaphylatoxins C3a and C5a are vasodilators in the canine coronary vasculature in vitro and in vivo.
Agents and actions 1991;34(3-4):345-9.
1991: N Venkatesh; J J Lynch; A C Uprichard; J M Kitzen; B N Singh; Benedict R Lucchesi
Hypothyroidism renders protection against lethal ventricular arrhythmias in a conscious canine model of sudden death.
Journal of cardiovascular pharmacology 1991;18(5):703-10.
1991: S C Black; Liguo Chi; D X Mu; Benedict R Lucchesi
The antifibrillatory actions of UK-68,798, a class III antiarrhythmic agent.
The Journal of pharmacology and experimental therapeutics 1991;258(2):416-23.
1991: Steven W Werns; Cyril Grum; Alejandra C Ventura; R A Hahn; P P Ho; R D Towner; Joseph C Fantone III; M A Schork; Benedict R Lucchesi
Xanthine oxidase inhibition does not limit canine infarct size.
Circulation 1991;83(3):995-1005.
1991: Liguo Chi; D X Mu; Benedict R Lucchesi
Electrophysiology and antiarrhythmic actions of E-4031 in the experimental animal model of sudden coronary death.
Journal of cardiovascular pharmacology 1991;17(2):285-95.
1991: Benedict R Lucchesi; P T Hoff; Y Tamura
Cardioprotective effects of amlodipine in animal models of ischemia and reperfusion.
Journal of cardiovascular pharmacology 1991;17 Suppl 1():S34-9.
1990: P T Hoff; Y Tamura; Benedict R Lucchesi
Cardioprotective effects of amlodipine on ischemia and reperfusion in two experimental models.
The American journal of cardiology 1990;66(18):10H-16H.
1990: G C Li; J A Vasquez; KP Gallagher; Benedict R Lucchesi
Myocardial protection with preconditioning.
Circulation 1990;82(2):609-19.
1990: Jonathon W Homeister; P T Hoff; D D Fletcher; Benedict R Lucchesi
Combined adenosine and lidocaine administration limits myocardial reperfusion injury.
Circulation 1990;82(2):595-608.
1990: Liguo Chi; D X Mu; Edward M Driscoll; Benedict R Lucchesi
Antiarrhythmic and electrophysiologic actions of CK-3579 and sematilide in a conscious canine model of sudden coronary death.
Journal of cardiovascular pharmacology 1990;16(2):312-24.
1990: J M Kitzen; Liguo Chi; A C Uprichard; Benedict R Lucchesi
Effects of combined thromboxane synthetase inhibition/thromboxane receptor antagonism in two models of sudden cardiac death in the canine: limited role for thromboxane.
Journal of cardiovascular pharmacology 1990;16(1):68-80.
1990: Benedict R Lucchesi
Myocardial ischemia, reperfusion and free radical injury.
The American journal of cardiology 1990;65(19):14I-23I.
1990: Steven W Werns; Benedict R Lucchesi
Free radicals and ischemic tissue injury.
Trends in pharmacological sciences 1990;11(4):161-6.
1990: Liguo Chi; A C Uprichard; Benedict R Lucchesi
Profibrillatory actions of pinacidil in a conscious canine model of sudden coronary death.
Journal of cardiovascular pharmacology 1990;15(3):452-64.
1990: J K Mickelson; P J Simpson; M Cronin; Jonathon W Homeister; E Laywell; J Kitzen; Benedict R Lucchesi
Antiplatelet antibody [7E3 F(ab')2] prevents rethrombosis after recombinant tissue-type plasminogen activator-induced coronary artery thrombolysis in a canine model.
Circulation 1990;81(2):617-27.
1990: W A Schumacher; Benedict R Lucchesi
Effect of diltiazem on experimental coronary artery thrombosis in dogs.
Pharmacology 1990;41(1):16-23.
1990: Benedict R Lucchesi
Modulation of leukocyte-mediated myocardial reperfusion injury.
Annual review of physiology 1990;52():561-76.
1990: P J Simpson; Robert F Todd III; J K Mickelson; Joseph C Fantone III; KP Gallagher; K A Lee; Y Tamura; M Cronin; Benedict R Lucchesi
Sustained limitation of myocardial reperfusion injury by a monoclonal antibody that alters leukocyte function.
Circulation 1990;81(1):226-37.
1990: James C Sisson; J Johnson; Gerald R Bolgos; J J Lynch; A Uprichard; Edward M Driscoll; Darryl Wieland; Benedict R Lucchesi
Portrayal of adrenergic denervation in the presence of myocardial infarction: a feasibility study.
American journal of physiologic imaging 1990;5(4):151-66.
1989: Benedict R Lucchesi; Steven W Werns; Joseph C Fantone III
The role of the neutrophil and free radicals in ischemic myocardial injury.
Journal of molecular and cellular cardiology 1989;21(12):1241-51.
1989: Benedict R Lucchesi
Role of calcium on excitation-contraction coupling in cardiac and vascular smooth muscle.
Circulation 1989;80(6 Suppl):IV1-13.
1989: P T Hoff; Y Tamura; Benedict R Lucchesi
Cardioprotective effects of amlodipine in the ischemic-reperfused heart.
The American journal of cardiology 1989;64(17):101I-115I discussion 115I-116I.
1989: A C Uprichard; Liguo Chi; J M Kitzen; J J Lynch; J W Frye; Benedict R Lucchesi
Celiprolol does not protect against ventricular tachycardia or sudden death in the conscious canine: a comparison with pindolol in assessing the role of intrinsic sympathomimetic activity.
The Journal of pharmacology and experimental therapeutics 1989;251(2):571-7.
1989: Benedict R Lucchesi; Y Tamura
Cardioprotective effects of amlodipine in the ischemic-reperfused heart.
American heart journal 1989;118(5 Pt 2):1121-2.
1989: J J Lynch; A C Uprichard; J W Frye; Edward M Driscoll; J M Kitzen; Benedict R Lucchesi
Effects of the positive inotropic agents milrinone and pimobendan on the development of lethal ischemic arrhythmias in conscious dogs with recent myocardial infarction.
Journal of cardiovascular pharmacology 1989;14(4):585-97.
1989: A C Uprichard; Liguo Chi; J J Lynch; Edward M Driscoll; J W Frye; Benedict R Lucchesi
Alinidine reduces the incidence of ischemic ventricular fibrillation in a conscious canine model, a protective effect antagonized by overdrive atrial pacing.
Journal of cardiovascular pharmacology 1989;14(3):475-82.
1989: J K Mickelson; P J Simpson; Benedict R Lucchesi
Streptokinase improves reperfusion blood flow after coronary artery occlusion.
International journal of cardiology 1989;23(3):373-84.
1989: J K Mickelson; P J Simpson; Benedict R Lucchesi
Antiplatelet monoclonal F(ab')2 antibody directed against the platelet GPIIb/IIIa receptor complex prevents coronary artery thrombosis in the canine heart.
Journal of molecular and cellular cardiology 1989;21(4):393-405.
1989: Liguo Chi; Y Tamura; P T Hoff; Mahender Macha; KP Gallagher; M A Schork; Benedict R Lucchesi
Effect of superoxide dismutase on myocardial infarct size in the canine heart after 6 hours of regional ischemia and reperfusion: a demonstration of myocardial salvage.
Circulation research 1989;64(4):665-75.
1989: S D Nelson; J J Lynch; D Sanders; D G Montgomery; Benedict R Lucchesi
Electrophysiologic actions and antifibrillatory efficacy of subacute left stellectomy in a conscious, post-infarction canine model of ischemic ventricular fibrillation.
International journal of cardiology 1989;22(3):365-76.
1989: Steven W Werns; Benedict R Lucchesi
Myocardial ischemia and reperfusion: the role of oxygen radicals in tissue injury.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1989;2(6):761-9.
1988: S E Mitsos; D Kim; Benedict R Lucchesi; Joseph C Fantone III
Modulation of myoglobin-H2O2-mediated peroxidation reactions by sulfhydryl compounds.
Laboratory investigation; a journal of technical methods and pathology 1988;59(6):824-30.
1988: W Söhngen; M M Winbury; J M Kitzen; Alejandra C Ventura; Benedict R Lucchesi
The mechanism for the clonidine-induced coronary artery dilatation in the canine heart.
Journal of cardiovascular pharmacology 1988;12(6):689-700.
1988: P J Simpson; Joseph C Fantone III; J K Mickelson; KP Gallagher; Benedict R Lucchesi
Identification of a time window for therapy to reduce experimental canine myocardial injury: suppression of neutrophil activation during 72 hours of reperfusion.
Circulation research 1988;63(6):1070-9.
1988: E Patterson; Benedict R Lucchesi
Electrophysiologic and antiarrhythmic actions of nadolol: acute ischemia in the presence of previous myocardial infarction.
American heart journal 1988;116(5 Pt 1):1223-32.
1988: Y Tamura; Liguo Chi; Edward M Driscoll; P T Hoff; Bruce Freeman; KP Gallagher; Benedict R Lucchesi
Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardial ischemia/reperfusion injury in canine heart.
Circulation research 1988;63(5):944-59.
1988: S D Nelson; Benedict R Lucchesi; D G Sanders; J J Lynch
Antiarrhythmic actions of left stellectomy in digitalis-mediated malignant ventricular arrhythmias in the postinfarcted canine heart.
Journal of cardiovascular pharmacology 1988;12(2):196-207.
1988: J K Mickelson; P J Simpson; C V Jackson; Benedict R Lucchesi
Protection of myocardial function and coronary vasculature by streptokinase.
Journal of cardiovascular pharmacology 1988;12(2):186-95.
1988: James C Sisson; J J Lynch; J Johnson; S Jaques; D Wu; Gerald R Bolgos; Benedict R Lucchesi; Darryl Wieland
Scintigraphic detection of regional disruption of adrenergic neurons in the heart.
American heart journal 1988;116(1 Pt 1):67-76.
1988: W Söhngen; J K Mickelson; P J Simpson; Benedict R Lucchesi
Recombinant single-chain urokinase-type plasminogen activator (rscu-PA) induces thrombolysis and systemic fibrinolysis in a canine model of coronary artery thrombosis.
Thrombosis research 1988;51(1):63-74.
1988: L O Larson; C B Hantler; J J Lynch; S N Landau; J A Buben; Benedict R Lucchesi; Paul R Knight
Cardiac electrophysiologic interactions of bepridil, a new calcium antagonist, with enflurane, halothane, and isoflurane.
Journal of cardiothoracic anesthesia 1988;2(3):346-55.
1988: J J Lynch; P J Simpson; KP Gallagher; Thomas McClanahan; K A Lee; Benedict R Lucchesi
Increase in experimental infarct size with digoxin in a canine model of myocardial ischemia-reperfusion injury.
American heart journal 1988;115(6):1171-82.
1988: J K Mickelson; P J Simpson; Benedict R Lucchesi
Myocardial dysfunction and coronary vasoconstriction induced by platelet-activating factor in the post-infarcted rabbit isolated heart.
Journal of molecular and cellular cardiology 1988;20(6):547-61.
1988: J M Kitzen; J J Lynch; Edward M Driscoll; Benedict R Lucchesi
Cardiac electrophysiologic and hemodynamic activity of pimobendan (UD-CG 115 BS), a new inotropic agent.
The Journal of pharmacology and experimental therapeutics 1988;244(3):929-39.
1988: P J Simpson; Robert F Todd III; Joseph C Fantone III; J K Mickelson; James D Griffin; Benedict R Lucchesi
Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mo1, anti-CD11b) that inhibits leukocyte adhesion.
The Journal of clinical investigation 1988;81(2):624-9.
1988: P J Simpson; J Mickelson; Joseph C Fantone III; KP Gallagher; Benedict R Lucchesi
Reduction of experimental canine myocardial infarct size with prostaglandin E1: inhibition of neutrophil migration and activation.
The Journal of pharmacology and experimental therapeutics 1988;244(2):619-24.
1988: J J Lynch; Benedict R Lucchesi
Effect of digoxin on the extent of injury and the severity of arrhythmias during acute myocardial ischemia and infarction in the dog.
Journal of cardiovascular pharmacology 1988;11(2):193-203.
1988: E Patterson; J K Gibson; Benedict R Lucchesi
Antiarrhythmic and arrhythmogenic actions of methyl lidocaine during the recovery phase after canine myocardial infarction.
Pharmacology 1988;36(2):73-83.
1988: J J Lynch; J M Kitzen; P T Hoff; Benedict R Lucchesi
Reduction in digitalis-associated postinfarction mortality with nadolol in conscious dogs.
American heart journal 1988;115(1 Pt 1):67-76.
1988: Steven W Werns; Benedict R Lucchesi
Leukocytes, oxygen radicals, and myocardial injury due to ischemia and reperfusion.
Free radical biology & medicine 1988;4(1):31-7.
1988: J M Kitzen; J J Lynch; A C Uprichard; N Venkatesh; Benedict R Lucchesi
Failure of thromboxane synthetase inhibition to protect the postinfarcted heart against the induction of ventricular tachycardia and ventricular fibrillation in a conscious canine model of sudden coronary death.
Pharmacology 1988;37(3):171-86.
1988: Steven W Werns; B T Eller; MJ Shea; P J Simpson; Robert C Dysko; G D Abrams; Benedict R Lucchesi
Protection of reperfused ischemic canine myocardium by CI-922, a new inhibitor of leukocyte activation.
Journal of cardiovascular pharmacology 1988;12(5):608-14.
1988: J J Lynch; J M Kitzen; P T Hoff; Benedict R Lucchesi
Effects of pimobendan (UD-CG 115 BS), a new positive inotropic agent, on ventricular tachycardia and ischemic ventricular fibrillation in a conscious canine model of recent myocardial infarction.
Journal of cardiovascular pharmacology 1988;12(5):547-54.
1988: Steven W Werns; P J Simpson; J K Mickelson; MJ Shea; Bertram Pitt; Benedict R Lucchesi
Sustained limitation by superoxide dismutase of canine myocardial injury due to regional ischemia followed by reperfusion.
Journal of cardiovascular pharmacology 1988;11(1):36-44.
1987: C V Jackson; T K Pope; Benedict R Lucchesi
Coronary artery vasodilation in the canine: physiological and pharmacological roles of beta-adrenergic receptors.
Journal of cardiovascular pharmacology 1987;10(2):196-204.
1987: P J Simpson; Benedict R Lucchesi
Free radicals and myocardial ischemia and reperfusion injury.
The Journal of laboratory and clinical medicine 1987;110(1):13-30.
1987: david wilber; J J Lynch; D G Montgomery; Benedict R Lucchesi
Alpha-adrenergic influences in canine ischemic sudden death: effects of alpha 1-adrenoceptor blockade with prazosin.
Journal of cardiovascular pharmacology 1987;10(1):96-106.
1987: J K Mickelson; P J Simpson; M T Gallas; Benedict R Lucchesi
Thromboxane synthetase inhibition with CGS 13080 improves coronary blood flow after streptokinase-induced thrombolysis.
American heart journal 1987;113(6):1345-52.
1987: U Giger; Laurence A Boxer; P J Simpson; Benedict R Lucchesi; R F Todd
Deficiency of leukocyte surface glycoproteins Mo1, LFA-1, and Leu M5 in a dog with recurrent bacterial infections: an animal model.
Blood 1987;69(6):1622-30.
1987: P J Simpson; J K Mickelson; Benedict R Lucchesi
Free radical scavengers in myocardial ischemia.
Federation proceedings 1987;46(7):2413-21.
1987: J J Lynch; S D Nelson; S A MacEwen; E M Driscoll; Benedict R Lucchesi
Antifibrillatory efficacy of concomitant beta adrenergic receptor blockade with dilevalol, the R,R-isomer of labetalol, and muscarinic receptor blockade with methylscopolamine.
The Journal of pharmacology and experimental therapeutics 1987;241(2):741-9.
1987: P J Simpson; J Mickelson; Joseph C Fantone III; K P Gallagher; Benedict R Lucchesi
Iloprost inhibits neutrophil function in vitro and in vivo and limits experimental infarct size in canine heart.
Circulation research 1987;60(5):666-73.
1987: Steven W Werns; MJ Shea; A Vaporciyan; S Phan; G D Abrams; A J Buda; Bertram Pitt; Benedict R Lucchesi
Superoxide dismutase does not cause scar thinning after myocardial infarction.
Journal of the American College of Cardiology 1987;9(4):898-902.
1987: S W Werns; Benedict R Lucchesi
Inflammation and myocardial infarction.
British medical bulletin 1987;43(2):460-71.
1987: J J Lynch; D G Montgomery; S D Nelson; D M Huante; Benedict R Lucchesi
Lack of concordance between the antiarrhythmic and antifibrillatory actions of UM-424, a quaternary ammonium analogue of propranolol.
Journal of cardiovascular pharmacology 1987;9(4):414-24.
1987: W H Kou; S D Nelson; J J Lynch; D G Montgomery; L DiCarlo; Benedict R Lucchesi
Effect of flecainide acetate on prevention of electrical induction of ventricular tachycardia and occurrence of ischemic ventricular fibrillation during the early postmyocardial infarction period: evaluation in a conscious canine model of sudden death.
Journal of the American College of Cardiology 1987;9(2):359-65.
1987: G A Kopia; Benedict R Lucchesi
Antifibrillatory action of bretylium: role of the sympathetic nervous system.
Pharmacology 1987;34(1):37-47.
1987: Benedict R Lucchesi; J K Mickelson; Jonathon W Homeister; C V Jackson
Interaction of the formed elements of blood with the coronary vasculature in vivo.
Federation proceedings 1987;46(1):63-72.
1987: P J Simpson; S E Mitsos; A Ventura; KP Gallagher; Joseph C Fantone III; G D Abrams; M A Schork; Benedict R Lucchesi
Prostacyclin protects ischemic reperfused myocardium in the dog by inhibition of neutrophil activation.
American heart journal 1987;113(1):129-37.
1987: S R Jolly; J N Kipnis; Benedict R Lucchesi
Cardiovascular depression by verapamil: reversal by glucagon and interactions with propranolol.
Pharmacology 1987;35(5):249-55.
1987: J J Lynch; L A DiCarlo; D G Montgomery; Benedict R Lucchesi
Effects of flecainide acetate on ventricular tachyarrhythmia and fibrillation in dogs with recent myocardial infarction.
Pharmacology 1987;35(4):181-93.
1987: B T Eller; J J Lynch; E Patterson; Benedict R Lucchesi
Electrophysiologic and antiarrhythmic actions of sulphinpyrazone and its sulfide metabolite G25671.
Pharmacology 1987;34(2-3):121-30.
1987: Benedict R Lucchesi
Role of neutrophils in ischemic heart disease: pathophysiologic role in myocardial ischemia and coronary artery reperfusion.
Cardiovascular clinics 1987;18(1):35-48.
1987: E Patterson; Marshal Shlafer; K M Walden; M B Khazaeli; D G Montgomery; Benedict R Lucchesi
Changes in cardiac muscle function and biochemistry produced by long-term amiodarone and amiodarone + triiodothyronine administration in the rabbit.
Pharmacology 1987;35(3):130-40.
1986: J J Lynch; D G Montgomery; Benedict R Lucchesi
Cardiac electrophysiologic actions of SCH 19927 (Dilevalol), the R,R-isomer of labetalol.
The Journal of pharmacology and experimental therapeutics 1986;239(3):719-23.
1986: C V Jackson; J K Mickelson; T K Pope; P S Rao; Benedict R Lucchesi
O2 free radical-mediated myocardial and vascular dysfunction.
The American journal of physiology 1986;251(6 Pt 2):H1225-31.
1986: J J Lynch; D G Montgomery; Benedict R Lucchesi
The effects of calcium entry blockade on the vulnerability of infarcted canine myocardium toward ventricular fibrillation.
The Journal of pharmacology and experimental therapeutics 1986;239(2):340-5.
1986: J J Lynch; L A DiCarlo; D G Montgomery; T Hassan; Benedict R Lucchesi
Electrophysiologic actions of pirmenol in dogs with recent myocardial infarction.
American heart journal 1986;112(4):752-8.
1986: S R Jolly; W J Kane; B G Hook; G D Abrams; Steven Kunkel; Benedict R Lucchesi
Reduction of myocardial infarct size by neutrophil depletion: effect of duration of occlusion.
American heart journal 1986;112(4):682-90.
1986: E Patterson; K M Walden; M B Khazaeli; D G Montgomery; Benedict R Lucchesi
Cardiac electrophysiologic effects of acute and chronic amiodarone administration in the isolated perfused rabbit heart: altered thyroid hormone metabolism.
The Journal of pharmacology and experimental therapeutics 1986;239(1):179-84.
1986: S E Mitsos; Joseph C Fantone III; KP Gallagher; K M Walden; P J Simpson; G D Abrams; M A Schork; Benedict R Lucchesi
Canine myocardial reperfusion injury: protection by a free radical scavenger, N-2-mercaptopropionyl glycine.
Journal of cardiovascular pharmacology 1986;8(5):978-88.
1986: J J Lynch; L A DiCarlo; D G Montgomery; Benedict R Lucchesi
Electrophysiologic effects of bepridil in normal and infarcted canine myocardium.
Journal of cardiovascular pharmacology 1986;8(5):957-66.
1986: david wilber; J J Lynch; Benedict R Lucchesi
Electrophysiologic effects of prazosin during acute myocardial ischemia.
European journal of pharmacology 1986;127(1-2):157-61.
1986: P J Simpson; C B Smith; G Rosenthal; Benedict R Lucchesi
Reduction in the incidence of thrombosis by the thromboxane synthetase inhibitor CGS 13080 in a canine model of coronary artery injury.
The Journal of pharmacology and experimental therapeutics 1986;238(2):497-501.
1986: C V Jackson; J K Mickelson; K Stringer; P S Rao; Benedict R Lucchesi
Electrolysis-induced myocardial dysfunction. A novel method for the study of free radical mediated tissue injury.
Journal of pharmacological methods 1986;15(4):305-20.
1986: Benedict R Lucchesi; J J Lynch
Preclinical assessment of antiarrhythmic drugs.
Federation proceedings 1986;45(8):2197-205.
1986: Steven W Werns; MJ Shea; Benedict R Lucchesi
Free radicals and myocardial injury: pharmacologic implications.
Circulation 1986;74(1):1-5.
1986: J J Lynch; D G Montgomery; Benedict R Lucchesi
Facilitation of lethal ventricular arrhythmias by therapeutic digoxin in conscious post infarction dogs.
American heart journal 1986;111(5):883-90.
1986: S E Mitsos; T E Askew; Joseph C Fantone III; Steven Kunkel; G D Abrams; A Schork; Benedict R Lucchesi
Protective effects of N-2-mercaptopropionyl glycine against myocardial reperfusion injury after neutrophil depletion in the dog: evidence for the role of intracellular-derived free radicals.
Circulation 1986;73(5):1077-86.
1986: J K Gibson; E Patterson; Benedict R Lucchesi
Electrophysiologic, antiarrhythmic and cardiovascular actions of UM301, a quaternary ammonium compound.
The Journal of pharmacology and experimental therapeutics 1986;237(1):318-25.
1986: J Lynch; D Montgomery; A Ventura; D Wilber; Benedict R Lucchesi
Antiarrhythmic vs. antifibrillatory activity of the basic diphenylhydantoin derivative 3-[3-(4-phenyl-1-piperidyl)propyl]-5-(4-methoxyphenyl)-5-phenylhydantoin hydrochloride.
Arzneimittel-Forschung 1986;36(3):475-81.
1986: Steven W Werns; MJ Shea; S E Mitsos; Robert C Dysko; Joseph C Fantone III; M A Schork; G D Abrams; Bertram Pitt; Benedict R Lucchesi
Reduction of the size of infarction by allopurinol in the ischemic-reperfused canine heart.
Circulation 1986;73(3):518-24.
1986: C V Jackson; W A Schumacher; Steven Kunkel; Edward M Driscoll; Benedict R Lucchesi
Platelet-activating factor and the release of a platelet-derived coronary artery vasodilator substance in the canine.
Circulation research 1986;58(2):218-29.
1986: Benedict R Lucchesi; K M Mullane
Leukocytes and ischemia-induced myocardial injury.
Annual review of pharmacology and toxicology 1986;26():201-24.
1985: G A Kopia; B T Eller; E Patterson; MJ Shea; Benedict R Lucchesi
Antiarrhythmic and electrophysiologic actions of clofilium in experimental canine models.
European journal of pharmacology 1985;116(1-2):49-61.
1985: J J Lynch; D G Montgomery; Alejandra C Ventura; Benedict R Lucchesi
Antiarrhythmic and electrophysiologic effects of bepridil in chronically infarcted conscious dogs.
The Journal of pharmacology and experimental therapeutics 1985;234(1):72-80.
1985: W A Schumacher; E C Lee; Benedict R Lucchesi
Augmentation of streptokinase-induced thrombolysis by heparin and prostacyclin.
Journal of cardiovascular pharmacology 1985;7(4):739-46.
1985: Steven W Werns; MJ Shea; E M Driscoll; C Cohen; G D Abrams; Bertram Pitt; Benedict R Lucchesi
The independent effects of oxygen radical scavengers on canine infarct size. Reduction by superoxide dismutase but not catalase.
Circulation research 1985;56(6):895-8.
1985: S R Jolly; W A Schumacher; Steven Kunkel; G D Abrams; J Liddicoat; Benedict R Lucchesi
Platelet depletion in experimental myocardial infarction.
Basic research in cardiology 1985;80(3):269-79.
1985: J J Lynch; L A Coskey; D G Montgomery; Benedict R Lucchesi
Prevention of ventricular fibrillation by dextrorotatory sotalol in a conscious canine model of sudden coronary death.
American heart journal 1985;109(5 Pt 1):949-58.
1985: J E Gadsby; PL Keyes; T S Schwartz; C H Bill; Benedict R Lucchesi
Do catecholamines play a physiologic role in regulating corpus luteum function in the pseudopregnant rabbit?
Biology of reproduction 1985;32(4):907-15.
1985: J J Lynch; R G Rahwan; Benedict R Lucchesi
Antifibrillatory actions of bepridil and butyl-MDI, two intracellular calcium antagonists.
European journal of pharmacology 1985;111(1):9-15.
1985: J K Gibson; E Patterson; Benedict R Lucchesi
The antiarrhythmic actions of intravenous and oral UM424 in postinfarction canine myocardium.
Journal of cardiovascular pharmacology 1985;7(2):211-8.
1985: S E Mitsos; S R Jolly; Benedict R Lucchesi
Protective effects of AICAriboside in the globally ischemic isolated cat heart.
Pharmacology 1985;31(3):121-31.
1985: david wilber; J J Lynch; D Montgomery; Benedict R Lucchesi
Postinfarction sudden death: significance of inducible ventricular tachycardia and infarct size in a conscious canine model.
American heart journal 1985;109(1):8-18.
1985: Steven W Werns; MJ Shea; Benedict R Lucchesi
Free radicals in ischemic myocardial injury.
Journal of free radicals in biology & medicine 1985;1(2):103-10.
1985: C V Jackson; S E Mitsos; P J Simpson; Edward M Driscoll; Benedict R Lucchesi
Effects of bepridil on regional and global myocardial ischemia/reperfusion-induced injury.
Pharmacology 1985;30(6):320-32.
1985: M L Hess; G T Rowe; M Caplan; J L Romson; Benedict R Lucchesi
Identification of hydrogen peroxide and hydroxyl radicals as mediators of leukocyte-induced myocardial dysfunction. Limitation of infarct size with neutrophil inhibition and depletion.
Advances in myocardiology 1985;5():159-75.
1985: B G Hook; W A Schumacher; D L Lee; S R Jolly; Benedict R Lucchesi
Experimental coronary artery thrombosis in the absence of thromboxane A2 synthesis: evidence for alternate pathways for coronary thrombosis.
Journal of cardiovascular pharmacology 1985;7(1):174-81.
1984: W A Schumacher; A J Buda; Benedict R Lucchesi
Streptokinase thrombolysis in experimental coronary artery thrombosis: pattern of reflow and effect of a stenosis.
International journal of cardiology 1984;6(5):615-27.
1984: J J Lynch; david wilber; D G Montgomery; T M Hsieh; E Patterson; Benedict R Lucchesi
Antiarrhythmic and antifibrillatory actions of the levo- and dextrorotatory isomers of sotalol.
Journal of cardiovascular pharmacology 1984;6(6):1132-41.
1984: MJ Shea; E M Driscoll; J L Romson; Bertram Pitt; Benedict R Lucchesi
Effect of OKY-1581, a thromboxane synthetase inhibitor, on coronary thrombosis in the conscious dog.
European journal of pharmacology 1984;105(3-4):285-91.
1984: E Patterson; D G Montgomery; J J Lynch; Benedict R Lucchesi
Cardiac electrophysiologic actions of KB-944 (Fostedil), a new calcium antagonist, in the anesthetized dog.
The Journal of pharmacology and experimental therapeutics 1984;230(3):632-40.
1984: E Patterson; J J Lynch; Benedict R Lucchesi
Antiarrhythmic and antifibrillatory actions of the beta adrenergic receptor antagonist, dl-sotalol.
The Journal of pharmacology and experimental therapeutics 1984;230(2):519-26.
1984: Benedict R Lucchesi
Rationale of therapy in the patient with acute myocardial infarction and life-threatening arrhythmias: a focus on bretylium.
The American journal of cardiology 1984;54(2):14A-19A.
1984: MJ Shea; J J Murtagh; S R Jolly; G D Abrams; Bertram Pitt; Benedict R Lucchesi
Beneficial effects of nafazatrom on ischemic reperfused myocardium.
European journal of pharmacology 1984;102(1):63-70.
1984: J M Zimmerman; E Patterson; Bertram Pitt; Benedict R Lucchesi
Antidysrhythmic actions of meobentine sulfate.
American heart journal 1984;107(6):1117-24.
1984: E Patterson; D J Amalfitano; Benedict R Lucchesi
Development of ventricular tachyarrhythmias in the conscious canine during the recovery phase of experimental ischemic injury: effect of bethanidine administration.
Journal of cardiovascular pharmacology 1984;6(3):470-5.
1984: MJ Shea; E M Driscoll; J L Romson; Bertram Pitt; Benedict R Lucchesi
The beneficial effects of nafazatrom (BAYg6575) on experimental coronary thrombosis.
American heart journal 1984;107(4):629-37.
1984: S R Jolly; W J Kane; M B Bailie; G D Abrams; Benedict R Lucchesi
Canine myocardial reperfusion injury. Its reduction by the combined administration of superoxide dismutase and catalase.
Circulation research 1984;54(3):277-85.
1984: P C Kirlin; J L Romson; Bertram Pitt; Benedict R Lucchesi
Regional myocardial contractile response to the beta-adrenergic stimulant prenalterol in the conscious dog following myocardial infarction. Mechanism of hemodynamic effect.
Pharmacology 1984;28(1):51-60.
1984: E Patterson; Benedict R Lucchesi
Antifibrillatory properties of the beta-adrenergic receptor antagonists, nadolol, sotalol, atenolol and propranolol, in the anesthetized dog.
Pharmacology 1984;28(3):121-9.
1983: W A Schumacher; Benedict R Lucchesi
Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity.
The Journal of pharmacology and experimental therapeutics 1983;227(3):790-6.
1983: J L Romson; B G Hook; Benedict R Lucchesi
Potentiation of the antithrombotic effect of prostacyclin by simultaneous administration of aminophylline in a canine model of coronary artery thrombosis.
The Journal of pharmacology and experimental therapeutics 1983;227(2):288-94.
1983: E Patterson; B T Eller; G D Abrams; J Vasiliades; Benedict R Lucchesi
Ventricular fibrillation in a conscious canine preparation of sudden coronary death--prevention by short- and long-term amiodarone administration.
Circulation 1983;68(4):857-64.
1983: E Patterson; Benedict R Lucchesi
Antifibrillatory actions of d,l-nadolol in a conscious canine model of sudden coronary death.
Journal of cardiovascular pharmacology 1983;5(5):737-44.
1983: E Patterson; Benedict R Lucchesi
Bretylium: a prototype for future development of antidysrhythmic agents.
American heart journal 1983;106(2):426-31.
1983: S R Jolly; Benedict R Lucchesi
Effect of BW755C in an occlusion-reperfusion model of ischemic myocardial injury.
American heart journal 1983;106(1 Pt 1):8-13.
1983: Bertram Pitt; MJ Shea; J L Romson; Benedict R Lucchesi
Prostaglandins and prostaglandin inhibitors in ischemic heart disease.
Annals of internal medicine 1983;99(1):83-92.
1983: J K Gibson; J R Stewart; Y P Li; Benedict R Lucchesi
Electrophysiologic effects of bretylium tosylate on the canine heart during coronary artery occlusion and reperfusion.
Journal of cardiovascular pharmacology 1983;5(4):517-24.
1983: K Holland; E Patterson; Benedict R Lucchesi
Prevention of ventricular fibrillation by bretylium in a conscious canine model of sudden coronary death.
American heart journal 1983;105(5):711-7.
1983: J L Romson; B G Hook; Steven Kunkel; G D Abrams; M A Schork; Benedict R Lucchesi
Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog.
Circulation 1983;67(5):1016-23.
1983: E Patterson; B T Eller; Benedict R Lucchesi
Effects of diltiazem upon experimental ventricular dysrhythmias.
The Journal of pharmacology and experimental therapeutics 1983;225(1):224-33.
1983: B T Eller; E Patterson; Benedict R Lucchesi
Ventricular fibrillation in a conscious canine model--its prevention by UM-272.
European journal of pharmacology 1983;87(4):407-13.
1983: B G Hook; J L Romson; S R Jolly; M B Bailie; Benedict R Lucchesi
Effect of zomepirac on experimental coronary artery thrombosis and ischemic myocardial injury in the conscious dog.
Journal of cardiovascular pharmacology 1983;5(2):302-8.
1983: E Patterson; P Stetson; Benedict R Lucchesi
Sublingual absorption of the quaternary ammonium antiarrhythmic agent, UM-272.
Pharmacology 1983;27(4):192-6.
1983: G A Kopia; E M Driscoll; K F Yeung; Benedict R Lucchesi
Antiarrhythmic and cardiovascular actions of the new antibiotic agent pirlimycin adenylate.
Pharmacology 1983;27(5):255-66.
1982: E Patterson; K Holland; B T Eller; Benedict R Lucchesi
Ventricular fibrillation resulting from ischemia at a site remote from previous myocardial infarction. A conscious canine model of sudden coronary death.
The American journal of cardiology 1982;50(6):1414-23.
1982: J L Romson; B G Hook; V H Rigot; M A Schork; D P Swanson; Benedict R Lucchesi
The effect of ibuprofen on accumulation of indium-111-labeled platelets and leukocytes in experimental myocardial infarction.
Circulation 1982;66(5):1002-11.
1982: E Patterson; J K Gibson; Benedict R Lucchesi
Electrophysiologic actions of lidocaine in a canine model of chronic myocardial ischemic damage--arrhythmogenic actions of lidocaine.
Journal of cardiovascular pharmacology 1982;4(6):925-34.
1982: J L Anderson; W N Brodine; E Patterson; H W Marshall; S D Allison; Benedict R Lucchesi
Serial electrophysiologic effects of bretylium in man and their correlation with plasma concentrations.
Journal of cardiovascular pharmacology 1982;4(6):871-82.
1982: P C Kirlin; J L Romson; Bertram Pitt; G D Abrams; M A Schork; Benedict R Lucchesi
Ibuprofen-mediated infarct size reduction: effects on regional myocardial function in canine myocardial infarction in canine myocardial infarction.
The American journal of cardiology 1982;50(4):849-56.
1982: E Patterson; Benedict R Lucchesi
Antifibrillatory actions of nadolol.
The Journal of pharmacology and experimental therapeutics 1982;223(1):144-52.
1982: J L Anderson; E M Tucker; S Pasyk; E Patterson; A B Simon; W E Burmeister; Benedict R Lucchesi; Bertram Pitt
Long-term intravenous infusion of antiarrhythmic drugs using a totally implanted drug delivery system.
The American journal of cardiology 1982;49(8):1954-8.
1982: H Colfer; P Stetson; Benedict R Lucchesi; J Wagner; Bertram Pitt
The nitroglycerin polymer gel matrix system: a new method for administering nitroglycerin evaluated with plasma nitroglycerin levels.
Journal of cardiovascular pharmacology 1982;4(3):521-5.
1982: S R Jolly; G D Abrams; J L Romson; M B Bailie; Benedict R Lucchesi
Effects of lodoxamide on ischemic reperfused myocardium.
Journal of cardiovascular pharmacology 1982;4(3):441-8.
1982: L C Anderson; V B Fiedler; B J Cohen; M R Anver; J L Simmons; Benedict R Lucchesi
Diagnostic exercise.
Laboratory animal science 1982;32(2):141-2.
1982: L R Bush; J L Romson; J L Ash; Benedict R Lucchesi
Effect of diltiazem on extent of ultimate myocardial injury resulting from temporary coronary artery occlusion in dogs.
Journal of cardiovascular pharmacology 1982;4(2):285-96.
1982: J L Romson; L R Bush; S R Jolly; Benedict R Lucchesi
Cardioprotective effects of ibuprofen in experimental regional and global myocardial ischemia.
Journal of cardiovascular pharmacology 1982;4(2):187-96.
1982: MJ Shea; L R Bush; J L Romson; E M Driscoll; Benedict R Lucchesi
The effect of diltiazem on coronary thrombosis in the conscious canine.
European journal of pharmacology 1982;77(1):67-70.
1982: J R Stewart; J K Gibson; Benedict R Lucchesi
Effect of infarct size limitation by propranolol on ventricular arrhythmias after myocardial infarction.
Annals of the New York Academy of Sciences 1982;382():223-8.
1982: P C Kirlin; Bertram Pitt; Benedict R Lucchesi
Intravenous prenalterol in acute and chronic heart failure.
Acta medica Scandinavica. Supplementum 1982;659():263-86.
1981: J L Romson; D W Haack; G D Abrams; Benedict R Lucchesi
Prevention of occlusive coronary artery thrombosis by prostacyclin infusion in the dog.
Circulation 1981;64(5):906-14.
1981: L R Bush; Y P Li; Marshal Shlafer; S R Jolly; Benedict R Lucchesi
Protective effects of diltiazem during myocardial ischemia in isolated cat hearts.
The Journal of pharmacology and experimental therapeutics 1981;218(3):653-61.
1981: P C Kirlin; Bertram Pitt; Benedict R Lucchesi
Comparative effects of prenalterol and dobutamine in a canine model of acute ischemic heart failure.
Journal of cardiovascular pharmacology 1981;3(4):896-905.
1981: E Patterson; Benedict R Lucchesi
Chronic ventricular tachyarrhythmias in the conscious dog: prevention by UM-272 (dimethylpropranolol).
Journal of cardiovascular pharmacology 1981;3(4):769-80.
1981: Marshal Shlafer; Marvin Kirsh; Benedict R Lucchesi; A D Slater; S Warren
Mitochondrial function after global cardiac ischemia and reperfusion: influences of organelle isolation protocols.
Basic research in cardiology 1981;76(3):250-66.
1981: J L Anderson; E Patterson; J G Wagner; T A Johnson; Benedict R Lucchesi; Bertram Pitt
Clinical pharmacokinetics of intravenous and oral bretylium tosylate in survivors of ventricular tachycardia or fibrillation: clinical application of a new assay for bretylium.
Journal of cardiovascular pharmacology 1981;3(3):485-99.
1981: D W Haack; L R Bush; Marshal Shlafer; Benedict R Lucchesi
Lanthanum staining of coronary microvascular endothelium: effects of ischemia reperfusion, propranolol, and atenolol.
Microvascular research 1981;21(3):362-76.
1981: E Patterson; J K Gibson; Benedict R Lucchesi
Postmyocardial infarction re-entrant ventricular arrhythmias in conscious dogs: suppression by bretylium tosylate.
The Journal of pharmacology and experimental therapeutics 1981;216(3):453-8.
1981: L R Bush; S Warren; C L Mesh; Benedict R Lucchesi
Comparative effects of aspartate and glutamate during myocardial ischemia.
Pharmacology 1981;23(6):297-304.
1980: W Mark Vogel; Benedict R Lucchesi
An isolated, blood-perfused, feline heart preparation for evaluating pharmacological interventions during myocardial ischemia.
Journal of pharmacological methods 1980;4(4):291-303.
1980: E Patterson; J K Gibson; Benedict R Lucchesi
Electrophysiologic effects of disopyramide phosphate on reentrant ventricular arrhythmia in conscious dogs after myocardial infarction.
The American journal of cardiology 1980;46(5):792-9.
1980: L R Bush; D W Haack; Marshal Shlafer; Benedict R Lucchesi
Protective effects of beta-adrenergic blockade in isolated ischemic hearts.
European journal of pharmacology 1980;67(2-3):209-17.
1980: J L Romson; L R Bush; D W Haack; Benedict R Lucchesi
The beneficial effects of oral ibuprofen on coronary artery thrombosis and myocardial ischemia in the conscious dog.
The Journal of pharmacology and experimental therapeutics 1980;215(1):271-8.
1980: J L Anderson; E Patterson; M Conlon; S Pasyk; Bertram Pitt; Benedict R Lucchesi
Kinetics of antifibrillatory effects of bretylium: correlation with myocardial drug concentrations.
The American journal of cardiology 1980;46(4):583-92.
1980: J L Anderson; E Patterson; J G Wagner; J R Stewart; H L Behm; Benedict R Lucchesi
Oral and intravenous bretylium disposition.
Clinical pharmacology and therapeutics 1980;28(4):468-78.
1980: N Korn; J K Gibson; F J Kniffen; Benedict R Lucchesi; V V Ranade; M Mimnaugh; T Yu; Raymond E Counsell
Potential organ- or tumor-imaging agents XIX: radioiodinated antiarrhythmic drugs as potential myocardial imaging agents.
Journal of pharmaceutical sciences 1980;69(9):1010-3.
1980: E Patterson; P Stetson; Benedict R Lucchesi
Plasma and myocardial tissue concentrations of UM-272 (N,N-dimethylpropranolol) after oral administration in dogs.
The Journal of pharmacology and experimental therapeutics 1980;214(2):449-53.
1980: J K Gibson; Benedict R Lucchesi
Electrophysiologic actions of UM-272 (Pranolium) on reentrant ventricular arrhythmias in postinfarction canine myocardium.
The Journal of pharmacology and experimental therapeutics 1980;214(2):347-53.
1980: L R Bush; Marshal Shlafer; D W Haack; Benedict R Lucchesi
Time-dependent changes in canine cardiac mitochondrial function and ultrastructure resulting from coronary occlusion and reperfusion.
Basic research in cardiology 1980;75(4):555-71.
1980: J L Romson; D W Haack; Benedict R Lucchesi
Electrical induction of coronary artery thrombosis in the ambulatory canine: a model for in vivo evaluation of anti-thrombotic agents.
Thrombosis research 1980;17(6):841-53.
1980: W Mark Vogel; J L Romson; L R Bush; Marshal Shlafer; Benedict R Lucchesi
Protective effects of dimethyl-propranolol (UM-272) during global ischemia of isolated feline hearts.
The Journal of pharmacology and experimental therapeutics 1980;212(3):560-8.
1980: K S Lo; K B Gantz; P L Stetson; Benedict R Lucchesi; Bertram Pitt
Disopyramide-induced ventricular tachycardia.
Archives of internal medicine 1980;140(3):413-4.
1980: E Patterson; P Stetson; Benedict R Lucchesi
Sensitive gas chromatographic assay for the quantitation of bretylium in plasma, urine and myocardial tissue.
Journal of chromatography 1980;181(1):33-9.
1980: J R Stewart; W E Burmeister; J Burmeister; Benedict R Lucchesi
Electrophysiologic and antiarrhythmic effects of phentolamine in experimental coronary artery occlusion and reperfusion in the dog.
Journal of cardiovascular pharmacology 1980;2(1):77-91.
1979: E Patterson; P Stetson; Benedict R Lucchesi
Disopyramide plasma and myocardial tissue concentrations as they relate to antiarrhythmic activity.
Journal of cardiovascular pharmacology 1979;1(5):541-50.
1979: S Warren; Benedict R Lucchesi; Marshal Shlafer
Effects of N-dimethyl propranolol (UM-272) on isolated cardiac mitochondria and microsomes.
Research communications in chemical pathology and pharmacology 1979;25(2):227-39.
1979: D D Ku; Benedict R Lucchesi
Ischemic-induced alterations in cardiac sensitivity to digitalis.
European journal of pharmacology 1979;57(2-3):135-47.
1979: Benedict R Lucchesi
Antiarrhythmic drugs. Key references.
Circulation 1979;59(5):1076-8.
1979: Charles R Schuster; Benedict R Lucchesi; G S Emley
The effects of d-amphetamine, meprobamate, and lobeline on the cigarette smoking behavior of normal human subjects.
NIDA research monograph 1979;(23):91-9.
1979: W Mark Vogel; D Lum; Benedict R Lucchesi
Methylprednisolone sodium succinate treatment in global ischemia of the cat isolated heart.
Journal of cardiovascular pharmacology 1979;1(1):53-68.
1978: J K Gibson; J L Burmeister; Benedict R Lucchesi
Electrophysiologic effects of UM-272 on myocardial ischemia in the canine heart.
The Journal of pharmacology and experimental therapeutics 1978;207(2):304-10.
1978: J W Keyes; P F Leonard; S L Brody; D J Svetkoff; W L Rogers; Benedict R Lucchesi
Myocardial infarct quantification in the dog by single photon emission computed tomography.
Circulation 1978;58(2):227-32.
1978: J W Keyes; P F Leonard; D J Svetkoff; S L Brody; W L Rogers; Benedict R Lucchesi
Myocardial imaging using emission computed tomography.
Radiology 1978;127(3):809-12.
1978: A Peterson; Benedict R Lucchesi; Marvin Kirsh
The effect of glucagon in animals on chronic propranolol therapy.
The Annals of thoracic surgery 1978;25(4):340-5.
1978: W Mark Vogel; Benedict R Lucchesi
Methylprednisolone and the size of myocardial infarcts.
Chest 1978;73(4):444.
1978: D D KU; Benedict R Lucchesi
Effects of dimethyl propranolol (UM-272; SC-27761) on myocardial ischemic injury in the canine heart after temporary coronary artery occlusion.
Circulation 1978;57(3):541-8.
1977: W Mark Vogel; V G Zannoni; G D Abrams; Benedict R Lucchesi
Inability of methylprednisolone sodium succinate to decrease infarct size or preserve enzyme activity measured 24 hours after coronary occlusion in the dog.
Circulation 1977;55(4):588-95.
1976: Benedict R Lucchesi; W E Burmeister; T E Lomas; G D Abrams
Ischemic changes in the canine heart as affected by the dimethyl quaternary analog of propranolol, UM-272 (SC-27761).
The Journal of pharmacology and experimental therapeutics 1976;199(2):310-28.
1976: L C Argenta; Marvin Kirsh; Edward L Bove; Vincent M Cimmino; Benedict R Lucchesi; J Straker; R Baker; R Lee; Herbert Sloan
A comparison of the hemodynamic effects of inotropic agents.
The Annals of thoracic surgery 1976;22(1):50-7.
1976: F J Kniffen; S Winokur; R E Counsell; Benedict R Lucchesi
The antiarrhythmic and cardiovascular properties of 1-dimethyl isopropylamino-3-(2-phenylphenoxy)-propan-2-ol chloride, UM-424.
The Journal of pharmacology and experimental therapeutics 1976;196(2):420-32.
1975: Benedict R Lucchesi; F J Kniffen
Pharmacological modification of arrhythmias after experimentally induced acute myocardial infarction. Drugs acting on the nervous system.
Circulation 1975;52(6 Suppl):III241-7.
1975: J J Bookstein; Marvin Kirsh; Richard L Prager; Benedict R Lucchesi; J M Dunn
Pharmacoangiographic evaluation of the hemodynamic significance of coronary artery stenoses.
Radiology 1975;117(1):5-10.
1975: D A Kroll; Benedict R Lucchesi
Antiarrhythmic and antifibrillatory properties of aprindine.
The Journal of pharmacology and experimental therapeutics 1975;194(2):427-34.
1975: G P Curtis; J Setchfield; Benedict R Lucchesi
The cardiac pharmacology of tolbutamide.
The Journal of pharmacology and experimental therapeutics 1975;194(1):264-73.
1975: F J Kniffen; T E Lomas; W E Burmeister; Benedict R Lucchesi
Effects of dimethyl quaternary propranolol (UM-272) on oxygen consumption and ischemic ST segment changes in the canine heart.
The Journal of pharmacology and experimental therapeutics 1975;194(1):234-43.
1975: S Winokur; N L Nobel-Allen; Benedict R Lucchesi
The positive inotropic effect of glucagon in the chronically failed right ventricle as demonstrated in the isolated cat heart.
European journal of pharmacology 1975;32(02):349-56.
1975: F J Kniffen; T E Lomas; R E Counsell; Benedict R Lucchesi
The antiarrhythmic and antifibrillatory actions of bretylium and its o-iodobenzyl trimethylammonium analog, UM-360.
The Journal of pharmacology and experimental therapeutics 1975;192(1):120-8.
1974: Benedict R Lucchesi
Recent advances in cardiovascular pharmacology.
AANA journal 1974;42(5):419-38.
1974: C J Nielsen; Benedict R Lucchesi
Inability of potassium canrenoate to convert experimentally induced ouabain arrhythmias in the canine heart.
Circulation research 1974;34(5):635-40.
1974: F J Kniffen; T E Lomas; N L Nobel-Allen; Benedict R Lucchesi
The comparative antiarrhythmic actions of lidocaine and its quarternary derivative, methyl lidocaine.
Circulation 1974;49(2):264-71.
1973: N Nobel-Allen; M Kirsch; Benedict R Lucchesi
Glucagon: its enhancement of cardiac performance in the cat with chronic heart failure.
The Journal of pharmacology and experimental therapeutics 1973;187(3):475-81.
1973: F J Kniffen; D P Schuster; Benedict R Lucchesi
Antiarrhythmic and electrophysiologic properties of UM-272, dimethyl quaternary propranolol, in the canine heart.
The Journal of pharmacology and experimental therapeutics 1973;187(2):260-8.
1973: Benedict R Lucchesi; N R Haley
Failure of potassium canrenoate to alter experimentally induced digitalis arrhythmias.
European journal of pharmacology 1973;22(3):256-62.
1973: D P Schuster; Benedict R Lucchesi; N L Nobel; M N Mimnaugh; R E Counsell; F J Kniffen
The antiarrhythmic properties of UM-272, the dimethyl quaternary derivative of propranolol.
The Journal of pharmacology and experimental therapeutics 1973;184(1):213-27.
1972: Benedict R Lucchesi; M Medina; F J Kniffen
The positive inotropic action of insulin in the canine heart.
European journal of pharmacology 1972;18(1):107-15.
1971: Marvin Kirsh; D R Kahn; Benedict R Lucchesi; O Gago; J H Dufek; R W Lee; David Robert Stutz; Herbert Sloan
Effect of glucagon on pulmonary vascular resistance.
Surgery 1971;70(3):439-42.
1971: Benedict R Lucchesi; R J Hodgeman
Effect of 4-(2-hydroxy-3-isopropylaminopropoxy) acetanilide (AY 21,011) on the myocardial and coronary vascular responses to adrenergic stimulation.
The Journal of pharmacology and experimental therapeutics 1971;176(1):200-11.
1970: M J Antonaccio; Benedict R Lucchesi
The interaction of glucagon with theophylline, PGE1, isoproeerenol, ouabain, and CaC1 on the dog isolated papillary muscle.
Life sciences. Pt. 1: Physiology and pharmacology 1970;9(19):1081-9.
1969: Benedict R Lucchesi; David Robert Stutz; R A Winfield
Glucagon: its enhancement of atrioventricular nodal pacemaker activity and failure to increase ventricular automaticity in dogs.
Circulation research 1969;25(2):183-90.
1969: J L Stickney; Benedict R Lucchesi
The effect of sympatholytic agents on the cardiovascular responses produced by the injection of acetylstrophanthidin into the cerebral ventricles.
European journal of pharmacology 1969;6(1):1-7.
1969: Benedict R Lucchesi; L S Whitsitt
The pharmacology of beta-adrenergic blocking agents.
Progress in cardiovascular diseases 1969;11(5):410-30.
1968: L S Whitsitt; Benedict R Lucchesi
Effects of beta-receptor blockade and glucagon on the atrioventricular transmission system in the dog.
Circulation research 1968;23(5):585-95.
1968: Benedict R Lucchesi; T Iwami
The antiarrhythmic properties of ICI 46037, a quaternary analog of propranolol.
The Journal of pharmacology and experimental therapeutics 1968;162(1):49-59.
1968: Benedict R Lucchesi
Cardiac actions of glucagon.
Circulation research 1968;22(6):777-87.
1968: G S Emley; Charles R Schuster; Benedict R Lucchesi
Trends observed in the time estimation of three stimulus intervals within and across sessions.
Perceptual and motor skills 1968;26(2):391-8.
1967: Benedict R Lucchesi; Charles R Schuster; G S Emley
The role of nicotine as a determinant of cigarette smoking frequency in man with observations of certain cardiovascular effects associated with the tobacco alkaloid.
Clinical pharmacology and therapeutics 1967;8(6):789-96.
1967: L S Whitsitt; Benedict R Lucchesi
Effects of propranolol and its stereoisomers upon coronary vascular resistance.
Circulation research 1967;21(3):305-17.
1967: T A Preston; R D Fletcher; Benedict R Lucchesi; Richard D Judge
Changes in myocardial threshold. Physiologic and pharmacologic factors in patients with implanted pacemakers.
American heart journal 1967;74(2):235-42.
1967: L S Whitsitt; Benedict R Lucchesi
The cardiac beta-adrenergic receptor blocking actions of propranolol and its stereoisomers.
Life sciences 1967;6(9):939-50.
1967: Benedict R Lucchesi; L S Whitsitt; J L Stickney
Antiarrhythmic effects of beta adrenergic blocking agents.
Annals of the New York Academy of Sciences 1967;139(3):940-51.
1966: Benedict R Lucchesi; L S Whitsitt; N L Brown
Propranolol (Inderal) in experimentally-induced cardiac arrhythmias.
Canadian journal of physiology and pharmacology 1966;44(4):543-7.
1966: T A Preston; Richard D Judge; Benedict R Lucchesi; D L Bowers
Myocardial threshold in patients with artificial pacemakers.
The American journal of cardiology 1966;18(1):83-9.
1965: Benedict R Lucchesi
THE EFFECTS OF PRONETHALOL AND ITS DEXTRO ISOMER UPON EXPERIMENTAL CARDIAC ARRHYTHMIAS.
The Journal of pharmacology and experimental therapeutics 1965;148():94-9.
1964: Benedict R Lucchesi
THE ACTION OF NETHALIDE UPON EXPERIMENTALLY INDUCED CARDIAC ARRHYTHMIAS.
The Journal of pharmacology and experimental therapeutics 1964;145():286-91.
1964: Benedict R Lucchesi; R SHIVAK
EFFECT OF QUINIDINE AND PROCAINE AMIDE UPON ACETYLSTROPHANTHIDIN CARDIOTOXICITY.
The Journal of pharmacology and experimental therapeutics 1964;143():367.
1962: Benedict R Lucchesi
The action of dichloroisoproterenol (DCI) and several other pharmacological agents upon the aconitine-induced ventricular arrhythmia in the isolated rabbit heart.
The Journal of pharmacology and experimental therapeutics 1962;137():291-300.
1961: Benedict R Lucchesi; H F HARDMAN
The influence of dichloroiso-proterenol (DCI) and related compounds upon ouabain and acetylstrophanthidin induced cardiac arrhythmias.
The Journal of pharmacology and experimental therapeutics 1961;132():372-81.