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Guy Ludbrook

Research Profile

Living Beings

Sheep

Chemicals & Drugs

Physiology

Cerebrovascular Circulation

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Brain

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Australia

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Publications

TOP 3
Cliff Grant; Guy L Ludbrook; E J O'Loughlin; T B Corcoran
An analysis of computer-assisted pre-screening prior to elective surgery.
R B Krishnamurthy; S Lai; H McConnell; J Ong; M J Chapman; C S Charlton; A O Fajumi; PE Macintyre; A M Martinez; S N O'Connor; R M Ousley; R N Upton; Guy L Ludbrook
Pharmacokinetics of oxycodone after subcutaneous administration in a critically ill population compared with a healthy cohort.
Kate Leslie; Guy L Ludbrook; D L Williams; Andrew R Bjorksten; C Y X Wu; E Williamson
Cardiac output and propofol concentrations in prone surgical patients.

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All Publications

2012: Cliff Grant; Guy L Ludbrook; E J O'Loughlin; T B Corcoran
An analysis of computer-assisted pre-screening prior to elective surgery.
Anaesthesia and intensive care 2012;40(2):297-304.
2012: R B Krishnamurthy; S Lai; H McConnell; J Ong; M J Chapman; C S Charlton; A O Fajumi; PE Macintyre; A M Martinez; S N O'Connor; R M Ousley; R N Upton; Guy L Ludbrook
Pharmacokinetics of oxycodone after subcutaneous administration in a critically ill population compared with a healthy cohort.
Anaesthesia and intensive care 2012;40(2):269-74.
2011: Kate Leslie; Guy L Ludbrook; D L Williams; Andrew R Bjorksten; C Y X Wu; E Williamson
Cardiac output and propofol concentrations in prone surgical patients.
Anaesthesia and intensive care 2011;39(5):868-74.
2010: Sarah J Capper; Susan Loo; Jason P Geue; Richard N Upton; Jennifer Ong; Pamela E Macintyre; Guy L Ludbrook
Pharmacokinetics of fentanyl after subcutaneous administration in volunteers.
European journal of anaesthesiology 2010;27(3):241-6.
2009: Guy L Ludbrook; Guy J Maddern
Doctor displacement: a political agenda or a health care imperative? Comment.
The Medical journal of Australia 2009;190(7):396-7.
2008: Cliff Grant; Guy L Ludbrook; E A Hampson; R Semenov; R Willis
Adverse physiological events under anaesthesia and sedation: a pilot audit of electronic patient records.
Anaesthesia and intensive care 2008;36(2):222-9.
2008: Richard N Upton; Mads Rasmussen; Cliff Grant; Allison M Martinez; Georg E Cold; Guy L Ludbrook
Pharmacokinetics and pharmacodynamics of indomethacin: effects on cerebral blood flow in anaesthetized sheep.
Clinical and experimental pharmacology & physiology 2008;35(3):317-23.
2007: Logan J Voss; Guy L Ludbrook; Cliff Grant; Richard Upton; James W Sleigh
A comparison of pharmacokinetic/pharmacodynamic versus mass-balance measurement of brain concentrations of intravenous anesthetics in sheep.
Anesthesia and analgesia 2007;104(6):1440-6, table of contents.
2006: Mads Rasmussen; Richard N Upton; Cliff Grant; Allison M Martinez; Georg E Cold; Guy L Ludbrook
The effects of indomethacin on intracranial pressure and cerebral hemodynamics during isoflurane or propofol anesthesia in sheep with intracranial hypertension.
Anesthesia and analgesia 2006;102(6):1823-9.
2006: Logan J Voss; Guy L Ludbrook; C Grant; James W Sleigh; J P M Barnard
Cerebral cortical effects of desflurane in sheep: comparison with isoflurane, sevoflurane and enflurane.
Acta anaesthesiologica Scandinavica 2006;50(3):313-9.
2005: Richard N Upton; Guy L Ludbrook
A physiologically based, recirculatory model of the kinetics and dynamics of propofol in man.
Anesthesiology 2005;103(2):344-52.
2005: S M Szekely; William B Runciman; RK Webb; Guy L Ludbrook
Crisis management during anaesthesia: desaturation.
Quality & safety in health care 2005;14(3):e6.
2005: Guy L Ludbrook; RK Webb; M Currie; LM Watterson
Crisis management during anaesthesia: myocardial ischaemia and infarction.
Quality & safety in health care 2005;14(3):e13.
2005: Richard N Upton; Guy L Ludbrook
Pharmacokinetic-pharmacodynamic modelling of the cardiovascular effects of drugs - method development and application to magnesium in sheep.
BMC pharmacology 2005;5():5.
2004: Richard N Upton; Cliff Grant; Allison M Martinez; Guy L Ludbrook
Recirculatory model of fentanyl disposition with the brain as the target organ.
British journal of anaesthesia 2004;93(5):687-97.
2004: James W Sleigh; D Alistair Steyn-Ross; Moira L Steyn-Ross; Cliff Grant; Guy L Ludbrook
Cortical entropy changes with general anaesthesia: theory and experiment.
Physiological measurement 2004;25(4):921-34.
2003: Guy L Ludbrook; Richard N Upton
Pharmacokinetic drug interaction between propofol and remifentanil?
Anesthesia and analgesia 2003;97(3):924-5.
2003: Richard N Upton; Guy L Ludbrook; Allison M Martinez; Cliff Grant; R W Milne
Cerebral and lung kinetics of morphine in conscious sheep after short intravenous infusions.
British journal of anaesthesia 2003;90(6):750-8.
2002: Guy L Ludbrook; Elizabeth Visco; Arthur M Lam
Propofol: relation between brain concentrations, electroencephalogram, middle cerebral artery blood flow velocity, and cerebral oxygen extraction during induction of anesthesia.
Anesthesiology 2002;97(6):1363-70.
2002: Guy L Ludbrook; Richard N Upton
Determinants of drug onset.
Current opinion in anaesthesiology 2002;15(4):409-14.
2002: John A Myburgh; Richard N Upton; Guy L Ludbrook; Allison Martinez; Cliff Grant
Cerebrovascular carbon dioxide reactivity in sheep: effect of propofol or isoflurane anaesthesia.
Anaesthesia and intensive care 2002;30(4):413-21.
2001: Guy L Ludbrook; PE Macintyre; H Douglas; L Ong; Richard N Upton
A mixture of alfentanil and morphine for rapid postoperative loading with opioid: theoretical basis and initial clinical investigation.
Anaesthesia 2001;56(8):739-44.
2001: D Zheng; Richard N Upton; Guy L Ludbrook; A Martinez
Acute cardiovascular effects of magnesium and their relationship to systemic and myocardial magnesium concentrations after short infusion in awake sheep.
The Journal of pharmacology and experimental therapeutics 2001;297(3):1176-83.
2001: Richard N Upton; Guy L Ludbrook; Cliff Grant; Allison Martinez
In vivo cerebral pharmacokinetics and pharmacodynamics of diazepam and midazolam after short intravenous infusion administration in sheep.
Journal of pharmacokinetics and pharmacodynamics 2001;28(2):129-53.
2001: Richard N Upton; Guy L Ludbrook; Cliff Grant
The cerebral and systemic kinetics of thiopentone and propofol in halothane anaesthetized sheep.
Anaesthesia and intensive care 2001;29(2):117-23.
2000: Richard N Upton; Guy L Ludbrook; Cliff Grant; David J Doolette
The effect of altered cerebral blood flow on the cerebral kinetics of thiopental and propofol in sheep.
Anesthesiology 2000;93(4):1085-94.
1999: Richard N Upton; Guy L Ludbrook; Cliff Grant; Allison M Martinez
Cardiac output is a determinant of the initial concentrations of propofol after short-infusion administration.
Anesthesia and analgesia 1999;89(3):545-52.
1999: Guy L Ludbrook; Richard N Upton; Cliff Grant; A Martinez
A compartmental analysis of the pharmacokinetics of propofol in sheep.
Journal of pharmacokinetics and biopharmaceutics 1999;27(3):329-38.
1999: Richard N Upton; Guy L Ludbrook
A model of the kinetics and dynamics of induction of anaesthesia in sheep: variable estimation for thiopental and comparison with propofol.
British journal of anaesthesia 1999;82(6):890-9.
1999: Guy L Ludbrook; M F James; Richard N Upton
The effect of magnesium sulfate on cerebral blood flow velocity, cardiovascular variables, and arterial carbon dioxide tension in awake sheep.
Journal of neurosurgical anesthesiology 1999;11(2):96-101.
1999: Guy L Ludbrook; Richard N Upton; C Grant; A Martinez
Prolonged dysequilibrium between blood and brain concentrations of propofol during infusions in sheep.
Acta anaesthesiologica Scandinavica 1999;43(2):206-11.
1999: Justin R Bessell; Guy L Ludbrook; SH Millard; PS Baxter; S S Ubhi; Guy J Maddern
Humidified gas prevents hypothermia induced by laparoscopic insufflation: a randomized controlled study in a pig model.
Surgical endoscopy 1999;13(2):101-5.
1998: Guy L Ludbrook; Richard N Upton; Cliff Grant; Allison Martinez
The effect of rate of administration on brain concentrations of propofol in sheep.
Anesthesia and analgesia 1998;86(6):1301-6.
1998: D Zheng; Richard N Upton; Allison M Martinez; Cliff Grant; Guy L Ludbrook
The influence of the bolus injection rate of propofol on its cardiovascular effects and peak blood concentrations in sheep.
Anesthesia and analgesia 1998;86(5):1109-15.
1997: Yi Fei Huang; Richard N Upton; EC Gray; Cliff Grant; D Zheng; Guy L Ludbrook
The effects of short intravenous infusions of thiopentone on myocardial function, blood flow and oxygen consumption in sheep.
Anaesthesia and intensive care 1997;25(6):627-33.
1997: Guy L Ludbrook; Richard N Upton
A physiological model of induction of anaesthesia with propofol in sheep. 2. Model analysis and implications for dose requirements.
British journal of anaesthesia 1997;79(4):505-13.
1997: Richard N Upton; Guy L Ludbrook
A physiological model of induction of anaesthesia with propofol in sheep. 1. Structure and estimation of variables.
British journal of anaesthesia 1997;79(4):497-504.
1997: Richard N Upton; Guy L Ludbrook; EC Gray; Cliff Grant
The cerebral pharmacokinetics of meperidine and alfentanil in conscious sheep.
Anesthesiology 1997;86(6):1317-25.
1997: Guy L Ludbrook; M Hitchcock; Richard N Upton
The difficult airway: propofol infusion as an alternative to gaseous induction.
Anaesthesia and intensive care 1997;25(1):71-3.
1996: Laurence E Mather; Richard N Upton; J L Huang; Guy L Ludbrook; E Gray; C Grant
The systemic and cerebral kinetics of thiopental in sheep: enantiomeric analysis.
The Journal of pharmacology and experimental therapeutics 1996;279(1):291-7.
1996: Richard N Upton; Yi Fei Huang; Cliff Grant; E C Gray; Guy L Ludbrook
Myocardial pharmacokinetics of thiopental in sheep after short-term administration: relationship to thiopental-induced reductions in myocardial contractility.
Journal of pharmaceutical sciences 1996;85(8):863-7.
1996: Guy L Ludbrook; Richard N Upton; Cliff Grant; E C Gray
Brain and blood concentrations of propofol after rapid intravenous injection in sheep, and their relationships to cerebral effects.
Anaesthesia and intensive care 1996;24(4):445-52.
1996: Richard N Upton; Guy L Ludbrook; Cliff Grant; E C Gray
In vivo relationships between the cerebral pharmacokinetics and pharmacodynamics of thiopentone in sheep after short-term administration.
Journal of pharmacokinetics and biopharmaceutics 1996;24(1):1-18.
1996: Guy L Ludbrook; Richard N Upton; Cliff Grant; E C Gray
Cerebral effects of propofol following bolus administration in sheep.
Anaesthesia and intensive care 1996;24(1):26-31.
1995: Guy L Ludbrook; Cliff Grant; R Upton; C Penhall
A method for frequent measurement of sedation and analgesia in sheep using the response to a ramped electrical stimulus.
Journal of pharmacological and toxicological methods 1995;33(1):17-22.
1994: R Upton; Cliff Grant; Guy L Ludbrook
An ultrasonic Doppler venous outflow method for the continuous measurement of cerebral blood flow in conscious sheep.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(4):680-8.
1994: Justin R Bessell; Guy J Maddern; Klaus H Manncke; Guy L Ludbrook; Glyn G Jamieson
Combined thoracoscopic and laparoscopic oesophagectomy and oesophagogastric reconstruction.
Endoscopic surgery and allied technologies 1994;2(1):32-6.
1993: R J Singleton; Robert Webb; Guy L Ludbrook; M A Fox
The Australian Incident Monitoring Study. Problems associated with vascular access: an analysis of 2000 incident reports.
Anaesthesia and intensive care 1993;21(5):664-9.
1993: R J Singleton; Guy L Ludbrook; Robert Webb; M A Fox
The Australian Incident Monitoring Study. Physical injuries and environmental safety in anaesthesia: an analysis of 2000 incident reports.
Anaesthesia and intensive care 1993;21(5):659-63.
1993: M A Fox; Robert Webb; R Singleton; Guy L Ludbrook; William B Runciman
The Australian Incident Monitoring Study. Problems with regional anaesthesia: an analysis of 2000 incident reports.
Anaesthesia and intensive care 1993;21(5):646-9.
1993: Guy L Ludbrook; Robert Webb; M A Fox; R J Singleton
The Australian Incident Monitoring Study. Problems before induction of anaesthesia: an analysis of 2000 incident reports.
Anaesthesia and intensive care 1993;21(5):593-5.
1993: I D Klepper; Robert Webb; Johan H van der Walt; Guy L Ludbrook; J Cockings
The Australian Incident Monitoring Study. The stethoscope: applications and limitations--an analysis of 2000 incident reports.
Anaesthesia and intensive care 1993;21(5):575-8.
1993: Guy L Ludbrook; W John Russell; Robert Webb; I D Klepper; M Currie
The Australian Incident Monitoring Study. The electrocardiograph: applications and limitations--an analysis of 2000 incident reports.
Anaesthesia and intensive care 1993;21(5):558-64.
1992: Guy L Ludbrook; Stephen C Helps; D F Gorman; P L Reilly; J B North; C Grant
The relative effects of hypoxic hypoxia and carbon monoxide on brain function in rabbits.
Toxicology 1992;75(1):71-80.
1992: Guy L Ludbrook; Stephen C Helps; D F Gorman
Cerebral blood flow response to increases in arterial CO2 tension during alfentanil anesthesia in the rabbit.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(3):529-32.