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Gabriele Ludewig

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Ian K Lai; Miao Li; Gabriele Ludewig; Kiran Dhakal; Gopi Gadupudi; Larry W Robertson; Alicia K Olivier
N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents.
Hua Shen; Larry W Robertson; Gabriele Ludewig
Regulation of paraoxonase 1 (PON1) in PCB 126-exposed male Sprague Dawley rats.
P K Senthilkumar; Larry W Robertson; Gabriele Ludewig
PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK).

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2012: Ian K Lai; Miao Li; Gabriele Ludewig; Kiran Dhakal; Gopi Gadupudi; Larry W Robertson; Alicia K Olivier
N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents.
Toxicology 2012;302(1):25-33.
2012: Hua Shen; Larry W Robertson; Gabriele Ludewig
Regulation of paraoxonase 1 (PON1) in PCB 126-exposed male Sprague Dawley rats.
Toxicology letters 2012;209(3):291-8.
2012: P K Senthilkumar; Larry W Robertson; Gabriele Ludewig
PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK).
Toxicology and applied pharmacology 2012;259(1):115-23.
2011: Bingxuan Wang; Kai Wang; Larry W Robertson; Gabriele Ludewig
Species difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126.
Xenobiotica; the fate of foreign compounds in biological systems 2011;41(12):1031-43.
2011: Ian K Lai; Gabriele Ludewig; Yingtao Chai; Wanda M Haschek; Donald Simmons; Rommel Tan; Bingxuan Wang; Kai Wang; WALTER WATSON; Larry W Robertson
Dietary selenium as a modulator of PCB 126-induced hepatotoxicity in male Sprague-Dawley rats.
Toxicological sciences : an official journal of the Society of Toxicology 2011;124(1):202-14.
2011: P K Senthilkumar; A J Klingelhutz; J A Jacobus; H Lehmler; Larry W Robertson; Gabriele Ludewig
Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat).
Toxicology letters 2011;204(1):64-70.
2010: J A Jacobus; B Wang; C Maddox; H Esch; L Lehmann; Larry W Robertson; Kai Wang; PA Kirby; Gabriele Ludewig
3-Methylcholanthrene (3-MC) and 4-chlorobiphenyl (PCB3) genotoxicity is gender-related in Fischer 344 transgenic rats.
Environment international 2010;36(8):970-9.
2010: Susanne Flor; Gabriele Ludewig
Polyploidy-induction by dihydroxylated monochlorobiphenyls: structure-activity-relationships.
Environment international 2010;36(8):962-9.
2010: Wei Xie; Kai Wang; Larry W Robertson; Gabriele Ludewig
Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites.
Environment international 2010;36(8):950-61.
2010: Ian Lai; Yingtao Chai; Don Simmons; Gregor Luthe; Mitchell C Coleman; Douglas R Spitz; Wanda M Haschek; Gabriele Ludewig; Larry W Robertson
Acute toxicity of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) in male Sprague-Dawley rats: effects on hepatic oxidative stress, glutathione and metals status.
Environment international 2010;36(8):918-23.
2010: Anna Ptak; Gabriele Ludewig; Agnieszka Rak; Weronika Nadolna; Michal Bochenek; Ewa L Gregoraszczuk
Induction of cytochrome P450 1A1 in MCF-7 human breast cancer cells by 4-chlorobiphenyl (PCB3) and the effects of its hydroxylated metabolites on cellular apoptosis.
Environment international 2010;36(8):935-41.
2010: Wei Xie; Gabriele Ludewig; Kai Wang; Hans-Joachim Lehmler
Model and cell membrane partitioning of perfluorooctanesulfonate is independent of the lipid chain length.
Colloids and surfaces. B, Biointerfaces 2010;76(1):128-36.
2009: Yang-won Suh; Garry R Buettner; Sujatha Venkataraman; Stephen E Treimer; Larry W Robertson; Gabriele Ludewig
UVA/B-induced formation of free radicals from decabromodiphenyl ether.
Environmental science & technology 2009;43(7):2581-8.
2008: Anna Ptak; Gabriele Ludewig; E Ł Gregoraszczuk
A low halogenated biphenyl (PCB3) increases CYP1A1 expression and activity via the estrogen receptor beta in the porcine ovary.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2008;59(3):577-88.
2008: Gregor Luthe; Regine Garcia Boy; James Jacobus; Bryan J Smith; Asif Rahaman; Larry W Robertson; Gabriele Ludewig
Xenobiotic geometry and media pH determine cytotoxicity through solubility.
Chemical research in toxicology 2008;21(5):1017-27.
2008: Hans-Joachim Lehmler; Ling Xu; Sandhya M Vyas; Vivian A Ojogun; Barbara L Knutson; Gabriele Ludewig
Synthesis, physicochemical properties and in vitro cytotoxicity of nicotinic acid ester prodrugs intended for pulmonary delivery using perfluorooctyl bromide as vehicle.
International journal of pharmaceutics 2008;353(1-2):35-44.
2008: Ewa L Gregoraszczuk; Gabriele Ludewig; Agnieszka Rak; Anna Gasińska
Effects of estradiol, PCB3, and their hydroxylated metabolites on proliferation, cell cycle, and apoptosis of human breast cancer cells.
Environmental toxicology and pharmacology 2008;25(2):227-33.
2008: Gabriele Ludewig; Harald Esch; Leane Lehmann; Larry W Robertson
Metabolic Activation of PCBs to Carcinogens in Vivo - A Review.
Environmental toxicology and pharmacology 2008;25(2):241-6.
2008: Catherine Maddox; Bingxuan Wang; Kai Wang; Patricia A Kirby; Gabriele Ludewig
Mutagenicity of 3-methylcholanthrene, pcb3, and 4-oh-pcb3 in the lung of transgenic bigblue rats.
Environmental toxicology and pharmacology 2008;25(2):260-6.
2007: Markus Alexander Zettner; Susanne Flor; Gabriele Ludewig; Jörg Wagner; Larry W Robertson; Leane Lehmann
Quinoid metabolites of 4-monochlorobiphenyl induce gene mutations in cultured Chinese hamster v79 cells.
Toxicological sciences : an official journal of the Society of Toxicology 2007;100(1):88-98.
2007: Leane Lehmann; Harald L Esch; Patricia A Kirby; Larry W Robertson; Gabriele Ludewig
4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats.
Carcinogenesis 2007;28(2):471-8.
2006: Anna Ptak; Gabriele Ludewig; Maria Kapiszewska; Zofia Magnowska; Hans-Joachim Lehmler; Larry W Robertson; Ewa L Gregoraszczuk
Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary.
Toxicology letters 2006;166(3):200-11.
2006: Ryan P Bender; Hans-Joachim Lehmler; Larry W Robertson; Gabriele Ludewig; Neil Osheroff
Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: altering enzyme function by blocking the N-terminal protein gate.
Biochemistry 2006;45(33):10140-52.
2006: Anna Ptak; Gabriele Ludewig; Larry Robertson; Hans-Joachim Lehmler; Ewa L Gregoraszczuk
In vitro exposure of porcine prepubertal follicles to 4-chlorobiphenyl (PCB3) and its hydroxylated metabolites: effects on sex hormone levels and aromatase activity.
Toxicology letters 2006;164(2):113-22.
2005: Prasada Rao S Kodavanti; Thomas R Ward; Gabriele Ludewig; Larry W Robertson; Linda S Birnbaum
Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effects, and structure-activity relationships.
Toxicological sciences : an official journal of the Society of Toxicology 2005;88(1):181-92.
2005: Izabela Kania-Korwel; Keri C Hornbuckle; Aaron M Peck; Gabriele Ludewig; Larry W Robertson; Wieslaw W Sulkowski; Parvaneh Espandiari; C Gary Gairola; Hans-Joachim Lehmler
Congener-specific tissue distribution of aroclor 1254 and a highly chlorinated environmental PCB mixture in rats.
Environmental science & technology 2005;39(10):3513-20.
2005: Anna Ptak; Gabriele Ludewig; Hans-Joachim Lehmler; Anna K Wójtowicz; Larry W Robertson; Ewa L Gregoraszczuk
Comparison of the actions of 4-chlorobiphenyl and its hydroxylated metabolites on estradiol secretion by ovarian follicles in primary cells in culture.
Reproductive toxicology (Elmsford, N.Y.) 2005;20(1):57-64.
2004: Yong Xu; Fang Fang; Gabriele Ludewig; Grace Jones; Davy Jones
A mutation found in the promoter region of the human survivin gene is correlated to overexpression of survivin in cancer cells.
DNA and cell biology 2004;23(9):527-37.
2004: Yong Xu; Fang Fang; Gabriele Ludewig; Grace Jones; Davy Jones
A mutation found in the promoter region of the human survivin gene is correlated to overexpression of survivin in cancer cells.
DNA and cell biology 2004;23(7):419-29.
2003: Nilufer Tampal; Larry W Robertson; Cidambi Srinivasan; Gabriele Ludewig
Polychlorinated biphenyls are not substrates for the multidrug resistance transporter-1.
Toxicology and applied pharmacology 2003;187(3):168-77.
2002: A Srinivasan; Larry W Robertson; Gabriele Ludewig
Sulfhydryl binding and topoisomerase inhibition by PCB metabolites.
Chemical research in toxicology 2002;15(4):497-505.
2001: A Srinivasan; Hans-Joachim Lehmler; Larry W Robertson; Gabriele Ludewig
Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites.
Toxicological sciences : an official journal of the Society of Toxicology 2001;60(1):92-102.
2000: Gabriele Ludewig; A Srinivasan; Larry W Robertson
Mechanisms of toxicity of PCB metabolites: generation of reactive oxygen species and glutathione depletion.
Central European journal of public health 2000;8 Suppl():15-7.
2000: Larry W Robertson; Parvaneh Espandiari; Hans-Joachim Lehmler; Daria Pereg; A Srinivasan; Nilufer Tampal; TP Twaroski; Gabriele Ludewig; Howard P Glauert; Jamal M Arif; R Gupta
Metabolism and activation of polychlorinated biphenyls (PCBs).
Central European journal of public health 2000;8 Suppl():14-5.
1999: Yong Xu; A Krishnan; X S Wan; Hideyuki J Majima; CC Yeh; Gabriele Ludewig; Edward J Kasarskis; Daret K St Clair
Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells.
Oncogene 1999;18(1):93-102.
1998: Parvaneh Espandiari; Gabriele Ludewig; Howard P Glauert; Larry W Robertson
Activation of hepatic NF-kappaB by the herbicide Dicamba (2-methoxy-3,6-dichlorobenzoic acid) in female and male rats.
Journal of biochemical and molecular toxicology 1998;12(6):339-44.
1994: Gabriele Ludewig; C Staben
Characterization of the PNT1 pentamidine resistance gene of Saccharomyces cerevisiae.
Antimicrobial agents and chemotherapy 1994;38(12):2850-6.
1994: Gabriele Ludewig; C Staben
Sensitivity of taxonomically diverse fungi to pentamidine isethionate.
The Journal of eukaryotic microbiology 1994;41(5):103S.
1994: Gabriele Ludewig; J M Williams; Y Li; C Staben
Effects of pentamidine isethionate on Saccharomyces cerevisiae.
Antimicrobial agents and chemotherapy 1994;38(5):1123-8.