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Roxanne Barrow

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Srinivasa Subramaniam; Richa Tyagi; Roxanne K Barrow; Francesco Errico; Seyun Kim; Robert G Mealer; Francesco Napolitano; Neelam Shahani; Solomon H Snyder; Alessandro Usiello
Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.
Asif K Mustafa; Gautam Sikka; Jochen Steppan; Rui Wang; Mario Amzel; Viachaslau Barodka; Roxanne K Barrow; Dan E Berkowitz; Anil K Bhunia; Farah K Gazi; Sadia K Gazi; Sung M Jung; Solomon H Snyder
Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels.
Seyun Kim; Sangwon F Kim; David Maag; Micah J Maxwell; Adam C Resnick; Krishna R Juluri; anutosh chakraborty; Michael A Koldobskiy; Seung Hun Cha; Roxanne K Barrow; Adele M Snowman; Solomon H Snyder
Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase.

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All Publications

2012: Srinivasa Subramaniam; Richa Tyagi; Roxanne K Barrow; Francesco Errico; Seyun Kim; Robert G Mealer; Francesco Napolitano; Neelam Shahani; Solomon H Snyder; Alessandro Usiello
Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.
Nature neuroscience 2012;15(2):191-3.
2011: Asif K Mustafa; Gautam Sikka; Jochen Steppan; Rui Wang; Mario Amzel; Viachaslau Barodka; Roxanne K Barrow; Dan E Berkowitz; Anil K Bhunia; Farah K Gazi; Sadia K Gazi; Sung M Jung; Solomon H Snyder
Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels.
Circulation research 2011;109(11):1259-68.
2011: Seyun Kim; Sangwon F Kim; David Maag; Micah J Maxwell; Adam C Resnick; Krishna R Juluri; anutosh chakraborty; Michael A Koldobskiy; Seung Hun Cha; Roxanne K Barrow; Adele M Snowman; Solomon H Snyder
Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase.
Cell metabolism 2011;13(2):215-21.
2010: Srinivasa Subramaniam; Robert G Mealer; Katherine M Sixt; Roxanne K Barrow; Alessandro Usiello; Solomon H Snyder
Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.
The Journal of biological chemistry 2010;285(27):20428-32.
2010: Asif K Mustafa; Abdullah Shafique Ahmad; Emil Zeynalov; Sadia K Gazi; Gautam Sikka; Jeffrey T Ehmsen; Roxanne K Barrow; Joseph T Coyle; Solomon H Snyder; Sylvain Dore
Serine racemase deletion protects against cerebral ischemia and excitotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(4):1413-6.
2009: Sriram Subramaniam; Katherine M Sixt; Roxanne K Barrow; Solomon H Snyder
Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity.
Science (New York, N.Y.) 2009;324(5932):1327-30.
2009: Asif K Mustafa; Damian B van Rossum; Randen L Patterson; David Maag; Jeffrey T Ehmsen; Sadia K Gazi; anutosh chakraborty; Roxanne K Barrow; Mario Amzel; Solomon H Snyder
Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2921-6.
2009: Asif K Mustafa; Moataz M Gadalla; Nilkantha Sen; Seyun Kim; Weitong Mu; Sadia K Gazi; Roxanne K Barrow; Guangdong Yang; Rui Wang; Solomon H Snyder
H2S signals through protein S-sulfhydration.
Science signaling 2009;2(96):ra72.
2008: Damian B van Rossum; Daniel Oberdick; Youssef Rbaibi; Gaurav Bhardwaj; Roxanne K Barrow; Nikolas Nikolaidis; Solomon H Snyder; Kirill Kiselyov; Randen L Patterson
TRP_2, a lipid/trafficking domain that mediates diacylglycerol-induced vesicle fusion.
The Journal of biological chemistry 2008;283(49):34384-92.
2008: Takatoshi Hikida; Asif K Mustafa; Kazuhisa Maeda; Kumiko Fujii; Roxanne K Barrow; Masoumeh Saleh; Richard Huganir; Solomon H Snyder; Kenji Hashimoto; Akira Sawa
Modulation of D-serine levels in brains of mice lacking PICK1.
Biological psychiatry 2008;63(10):997-1000.
2007: Asif K Mustafa; Manish Kumar; Balakrishnan Selvakumar; Gary P H Ho; Jeffrey T Ehmsen; Roxanne K Barrow; Mario Amzel; Solomon H Snyder
Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2950-5.
2007: Nikolas Nikolaidis; Dimitra Chalkia; DAVID WATKINS; Roxanne K Barrow; Solomon H Snyder; Damian B van Rossum; Randen L Patterson
Ancient origin of the new developmental superfamily DANGER.
PloS one 2007;2(2):e204.
2006: Damian B van Rossum; Randen L Patterson; King-Ho Cheung; Roxanne K Barrow; Viktoriya Syrovatkina; Gregory S Gessell; Scott G Burkholder; DAVID WATKINS; J Kevin Foskett; Solomon H Snyder
DANGER, a novel regulatory protein of inositol 1,4,5-trisphosphate-receptor activity.
The Journal of biological chemistry 2006;281(48):37111-6.
2005: Damian B van Rossum; Randen L Patterson; Sumit Sharma; Roxanne K Barrow; Michael Kornberg; Donald L Gill; Solomon H Snyder
Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain.
Nature 2005;434(7029):99-104.
2005: Paul M Kim; Hiroyuki Aizawa; Peter S Kim; Alex S Huang; Sasrutha R Wickramasinghe; Amir H Kashani; Roxanne K Barrow; Richard Huganir; Anirvan Ghosh; Solomon H Snyder
Serine racemase: activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2105-10.
2005: Randen L Patterson; Damian B van Rossum; Adam I Kaplin; Roxanne K Barrow; Solomon H Snyder
Inositol 1,4,5-trisphosphate receptor/GAPDH complex augments Ca2+ release via locally derived NADH.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1357-9.
2004: Randen L Patterson; Damian B van Rossum; Roxanne K Barrow; Solomon H Snyder
RACK1 binds to inositol 1,4,5-trisphosphate receptors and mediates Ca2+ release.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2328-32.
2004: Damian B van Rossum; Randen L Patterson; Kirill Kiselyov; Darren Boehning; Roxanne K Barrow; Donald L Gill; Solomon H Snyder
Agonist-induced Ca2+ entry determined by inositol 1,4,5-trisphosphate recognition.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2323-7.
2000: Crystal C Watkins; Akira Sawa; Samie R Jaffrey; Seth Blackshaw; Roxanne K Barrow; Solomon H Snyder; Christopher D Ferris
Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy.
The Journal of clinical investigation 2000;106(3):373-84.
2000: DE Barañano; H Wolosker; Byoung-Il Bae; Roxanne K Barrow; Solomon H Snyder; Christopher D Ferris
A mammalian iron ATPase induced by iron.
The Journal of biological chemistry 2000;275(20):15166-73.
1999: Christopher D Ferris; Samie R Jaffrey; Akira Sawa; Masaaki Takahashi; S D Brady; Roxanne K Barrow; S A Tysoe; H Wolosker; DE Barañano; Sylvain Dore; KD Poss; Solomon H Snyder
Haem oxygenase-1 prevents cell death by regulating cellular iron.
Nature cell biology 1999;1(3):152-7.
1999: DM Sabatini; Roxanne K Barrow; Seth Blackshaw; PE Burnett; MM Lai; M E Field; B A Bahr; Jeffrey R Kirsch; H Betz; Solomon H Snyder
Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling.
Science (New York, N.Y.) 1999;284(5417):1161-4.
1998: PE Burnett; Roxanne K Barrow; NA Cohen; Solomon H Snyder; DM Sabatini
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1432-7.
1995: DM Sabatini; B A Pierchala; Roxanne K Barrow; M J Schell; Solomon H Snyder
The rapamycin and FKBP12 target (RAFT) displays phosphatidylinositol 4-kinase activity.
The Journal of biological chemistry 1995;270(36):20875-8.
1993: R J Mourey; V A Estevez; J F Marecek; Roxanne K Barrow; Glenn D Prestwich; Solomon H Snyder
Inositol 1,4,5-trisphosphate receptors: labeling the inositol 1,4,5-trisphosphate binding site with photoaffinity ligands.
Biochemistry 1993;32(7):1719-26.
1992: R J Mourey; Ted M Dawson; Roxanne K Barrow; A E Enna; Solomon H Snyder
[3H]noscapine binding sites in brain: relationship to indoleamines and the phosphoinositide and adenylyl cyclase messenger systems.
Molecular pharmacology 1992;42(4):619-26.
1992: A B Theibert; V A Estevez; R J Mourey; J F Marecek; Roxanne K Barrow; Glenn D Prestwich; Solomon H Snyder
Photoaffinity labeling and characterization of isolated inositol 1,3,4,5-tetrakisphosphate- and inositol hexakisphosphate-binding proteins.
The Journal of biological chemistry 1992;267(13):9071-9.
1991: A B Theibert; V A Estevez; Christopher D Ferris; Sonye K Danoff; Roxanne K Barrow; Glenn D Prestwich; Solomon H Snyder
Inositol 1,3,4,5-tetrakisphosphate and inositol hexakisphosphate receptor proteins: isolation and characterization from rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3165-9.