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Sarah Lummis

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Radovan Spurny; Sergei V Strelkov; Jan Tytgat; David A Weston; Daniel Bertrand; Sonia Bertrand; Bert Billen; Marijke Brams; Sarah Debaveye; Rebecca J Howard; Sarah C R Lummis; Kerry L Price; Chris Ulens
Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
Divya Kesters; Sarah C R Lummis; August B Smit; Radovan Spurny; Andrew J Thompson; Marijke Brams; Matthis Geitmann; Albert Guskov; René Van Elk; Jose M Villalgordo; U Helena Danielson; Chris Ulens
Structural basis of ligand recognition in 5-HT3 receptors.
John A O'Brien; Sarah C R Lummis
Biolistic transfection of neurons in organotypic brain slices.

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2013: Radovan Spurny; Sergei V Strelkov; Jan Tytgat; David A Weston; Daniel Bertrand; Sonia Bertrand; Bert Billen; Marijke Brams; Sarah Debaveye; Rebecca J Howard; Sarah C R Lummis; Kerry L Price; Chris Ulens
Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
The Journal of biological chemistry 2013;288(12):8355-64.
2013: Divya Kesters; Sarah C R Lummis; August B Smit; Radovan Spurny; Andrew J Thompson; Marijke Brams; Matthis Geitmann; Albert Guskov; René Van Elk; Jose M Villalgordo; U Helena Danielson; Chris Ulens
Structural basis of ligand recognition in 5-HT3 receptors.
EMBO reports 2013;14(1):49-56.
2013: John A O'Brien; Sarah C R Lummis
Biolistic transfection of neurons in organotypic brain slices.
Methods in molecular biology (Clifton, N.J.) 2013;940():157-66.
2012: Sarah C R Lummis
5-HT(3) receptors.
The Journal of biological chemistry 2012;287(48):40239-45.
2012: Jamie A Ashby; Netta Cohen; Federico Comitani; Dennis A Dougherty; Ian V McGonigle; Carla Molteni; Kerry L Price; Sarah C R Lummis
GABA binding to an insect GABA receptor: a molecular dynamics and mutagenesis study.
Biophysical journal 2012;103(10):2071-81.
2012: Shelley H Huang; Graham A R Johnston; Trevor M Lewis; Sarah C R Lummis; Andrew J Thompson; Mary Chebib; Rujee K Duke
Mixed antagonistic effects of the ginkgolides at recombinant human ρ1 GABAC receptors.
Neuropharmacology 2012;63(6):1127-39.
2012: Radovan Spurny; Mark Verheij; Daniel Bertrand; Sonia Bertrand; Marijke Brams; Pierre-Jean Corringer; Iwan J P De Esch; Dennis A Dougherty; Margot Ernst; Pierre Legrand; Sarah C R Lummis; Hugues Nury; Kerry Price; Joachim Ramerstorfer; Werner Sieghart; Chris Ulens
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(44):E3028-34.
2012: Mark H P Verheij; Rob Leurs; Sarah C R Lummis; Andrew J Thompson; Jacqueline van Muijlwijk-Koezen; Iwan J P De Esch
Design, synthesis, and structure-activity relationships of highly potent 5-HT₃ receptor ligands.
Journal of medicinal chemistry 2012;55(20):8603-14.
2012: Atilla Akdemir; Chris de Graaf; Ewald Edink; Albert J Kooistra; Sarah C R Lummis; Andrew J Thompson; Iwan J P De Esch
Identification of novel α7 nicotinic receptor ligands by in silico screening against the crystal structure of a chimeric α7 receptor ligand binding domain.
Bioorganic & medicinal chemistry 2012;20(19):5992-6002.
2012: Andrew J Thompson; Chris Ulens; Mona Alqazzaz; Sarah C R Lummis
The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor.
Neuropharmacology 2012;63(4):761-7.
2012: Yuri N Utkin; Christoph Weise; Maxim N Zhmak; Tatyana V Andreeva; Daniel Bertrand; Ngoc Anh Hoang; Igor E Kasheverov; Elena V Kryukova; Sarah C R Lummis; Joachim Ramerstorfer; Werner Sieghart; Vladislav G Starkov; Andrew J Thompson; Victor I Tsetlin
Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor.
The Journal of biological chemistry 2012;287(32):27079-86.
2012: Andrew J Thompson; Ian McGonigle; Rujee Duke; Graham A R Johnston; Sarah C R Lummis
A single amino acid determines the toxicity of Ginkgo biloba extracts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(5):1884-91.
2011: Mark H P Verheij; Henry Vischer; Obbe P Zuiderveld; Chris de Graaf; Gerdien E de Kloe; Saskia Hulscher; Rob Leurs; Sarah C R Lummis; Saskia Nijmeijer; Linda Silvestri; Rogier A Smits; Andrew J Thompson; Jacqueline van Muijlwijk-Koezen; Iwan J P De Esch
Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H₄ and the ion channel serotonin 5-HT₃A.
Bioorganic & medicinal chemistry letters 2011;21(18):5460-4.
2011: Sarah C R Lummis; Ian McGonigle; Jamie A Ashby; Dennis A Dougherty
Two amino acid residues contribute to a cation-π binding interaction in the binding site of an insect GABA receptor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(34):12371-6.
2011: Stephan A Pless; Ariele P Hanek; Kerry L Price; Joseph W Lynch; Henry A Lester; Dennis A Dougherty; Sarah C R Lummis
A cation-π interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists.
Molecular pharmacology 2011;79(4):742-8.
2011: Andrew J Thompson; Gavin E Jarvis; Rujee K Duke; Graham A R Johnston; Sarah C R Lummis
Ginkgolide B and bilobalide block the pore of the 5-HT₃receptor at a location that overlaps the picrotoxin binding site.
Neuropharmacology 2011;60(2-3):488-95.
2011: Daniel W Wheeler; Andrew J Thompson; Federico Corletto; Jill Reckless; Justin C T Loke; Nicolas Lapaque; Andrew J Grant; Pietro Mastroeni; David J Grainger; Claire L Padgett; John A O'Brien; Nigel G A Miller; John Trowsdale; Sarah C R Lummis; David K Menon; John S Beech
Anaesthetic impairment of immune function is mediated via GABA(A) receptors.
PloS one 2011;6(2):e17152.
2010: Gracia X J Quek; Andrew J Thompson; Nathan Absalom; Joseph I Ambrus; Jill I Halliday; Diana Lin; Martin Lochner; Sarah C R Lummis; Malcolm D McLeod; Mary Chebib
Identifying the binding site of novel methyllycaconitine (MLA) analogs at α4β2 nicotinic acetylcholine receptors.
ACS chemical neuroscience 2010;1(12):796-809.
2010: Andrew J Thompson; Henry A Lester; Sarah C R Lummis
The structural basis of function in Cys-loop receptors.
Quarterly reviews of biophysics 2010;43(4):449-99.
2010: Ian McGonigle; Sarah C R Lummis
Molecular characterization of agonists that bind to an insect GABA receptor.
Biochemistry 2010;49(13):2897-902.
2010: Sanjeev Kumar V Vernekar; Hasan Y Hallaq; Guy J Clarkson; Andrew J Thompson; Linda Silvestri; Sarah C R Lummis; Martin Lochner
Toward biophysical probes for the 5-HT3 receptor: structure-activity relationship study of granisetron derivatives.
Journal of medicinal chemistry 2010;53(5):2324-8.
2009: Ian McGonigle; Sarah C R Lummis
RDL receptors.
Biochemical Society transactions 2009;37(Pt 6):1404-6.
2009: Sarah C R Lummis
Locating GABA in GABA receptor binding sites.
Biochemical Society transactions 2009;37(Pt 6):1343-6.
2009: Claudio Melis; Giovanni Bussi; Sarah C R Lummis; Carla Molteni
Trans-cis switching mechanisms in proline analogues and their relevance for the gating of the 5-HT3 receptor.
The journal of physical chemistry. B 2009;113(35):12148-53.
2009: Mariana Bartos; Kerry L Price; Sarah C R Lummis; Cecilia Bouzat
Glutamine 57 at the complementary binding site face is a key determinant of morantel selectivity for {alpha}7 nicotinic receptors.
The Journal of biological chemistry 2009;284(32):21478-87.
2009: Nicholas M Barnes; Tim G Hales; Sarah C R Lummis; John A Peters
The 5-HT3 receptor--the relationship between structure and function.
Neuropharmacology 2009;56(1):273-84.
2009: Andrew J Thompson; Sarah C R Lummis
Calcium modulation of 5-HT3 receptor binding and function.
Neuropharmacology 2009;56(1):285-91.
2008: Claudio Melis; Sarah C R Lummis; Carla Molteni
Molecular dynamics simulations of GABA binding to the GABAC receptor: the role of Arg104.
Biophysical journal 2008;95(9):4115-23.
2008: Stephan A Pless; Kat S Millen; Ariele P Hanek; Joseph W Lynch; Henry A Lester; Sarah C R Lummis; Dennis A Dougherty
A cation-pi interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(43):10937-42.
2008: Kerry L Price; Kiowa S Bower; Andrew J Thompson; Henry A Lester; Dennis A Dougherty; Sarah C R Lummis
A hydrogen bond in loop A is critical for the binding and function of the 5-HT3 receptor.
Biochemistry 2008;47(24):6370-7.
2008: Andrew J Thompson; Sarah C R Lummis
Antimalarial drugs inhibit human 5-HT(3) and GABA(A) but not GABA(C) receptors.
British journal of pharmacology 2008;153(8):1686-96.
2008: Kiowa S Bower; Kerry L Price; Laura E C Sturdee; Mariza Dayrell; Dennis A Dougherty; Sarah C R Lummis
5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function.
European journal of pharmacology 2008;580(3):291-7.
2008: Claire L Padgett; Sarah C R Lummis
The F-loop of the GABA A receptor gamma2 subunit contributes to benzodiazepine modulation.
The Journal of biological chemistry 2008;283(5):2702-8.
2007: John A O'Brien; Sarah C R Lummis
Diolistics: incorporating fluorescent dyes into biological samples using a gene gun.
Trends in biotechnology 2007;25(11):530-4.
2007: Kerry L Price; Katherine S Millen; Sarah C R Lummis
Transducing agonist binding to channel gating involves different interactions in 5-HT3 and GABAC receptors.
The Journal of biological chemistry 2007;282(35):25623-30.
2007: Andrew J Thompson; M Lochner; Sarah C R Lummis
The antimalarial drugs quinine, chloroquine and mefloquine are antagonists at 5-HT3 receptors.
British journal of pharmacology 2007;151(5):666-77.
2007: Andrew J Thompson; Sarah C R Lummis
The 5-HT3 receptor as a therapeutic target.
Expert opinion on therapeutic targets 2007;11(4):527-40.
2007: Claire L Padgett; Ariele P Hanek; Henry A Lester; Dennis A Dougherty; Sarah C R Lummis
Unnatural amino acid mutagenesis of the GABA(A) receptor binding site residues reveals a novel cation-pi interaction between GABA and beta 2Tyr97.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(4):886-92.
2006: Claudio Melis; Pak-Lee Chau; Kerry L Price; Sarah C R Lummis; Carla Molteni
Exploring the binding of serotonin to the 5-HT3 receptor by density functional theory.
The journal of physical chemistry. B 2006;110(51):26313-9.
2006: Nora L Sullivan; Andrew J Thompson; Kerry L Price; Sarah C R Lummis
Defining the roles of Asn-128, Glu-129 and Phe-130 in loop A of the 5-HT3 receptor.
Molecular membrane biology 2006;23(5):442-51.
2006: Neil J Harrison; Sarah C R Lummis
Locating the carboxylate group of GABA in the homomeric rho GABA(A) receptor ligand-binding pocket.
The Journal of biological chemistry 2006;281(34):24455-61.
2006: Andrew J Thompson; Claire L Padgett; Sarah C R Lummis
Mutagenesis and molecular modeling reveal the importance of the 5-HT3 receptor F-loop.
The Journal of biological chemistry 2006;281(24):16576-82.
2006: Andrew J Thompson; Pak-Lee Chau; S L Chan; Sarah C R Lummis
Unbinding pathways of an agonist and an antagonist from the 5-HT3 receptor.
Biophysical journal 2006;90(6):1979-91.
2006: Neil J Harrison; Sarah C R Lummis
Molecular modeling of the GABA(C) receptor ligand-binding domain.
Journal of molecular modeling 2006;12(3):317-24.
2006: John A O'Brien; Sarah C R Lummis
Diolistic labeling of neuronal cultures and intact tissue using a hand-held gene gun.
Nature protocols 2006;1(3):1517-21.
2006: John A O'Brien; Sarah C R Lummis
Biolistic transfection of neuronal cultures using a hand-held gene gun.
Nature protocols 2006;1(2):977-81.
2006: Andrew J Thompson; Nora L Sullivan; Sarah C R Lummis
Characterization of 5-HT3 receptor mutations identified in schizophrenic patients.
Journal of molecular neuroscience : MN 2006;30(3):273-81.
2006: Andrew J Thompson; Sarah C R Lummis
5-HT3 receptors.
Current pharmaceutical design 2006;12(28):3615-30.
2006: David C Reeves; Sarah C R Lummis
Detection of human and rodent 5-HT3B receptor subunits by anti-peptide polyclonal antibodies.
BMC neuroscience 2006;7():27.
2005: Kerry L Price; Sarah C R Lummis
FlexStation examination of 5-HT3 receptor function using Ca2+ - and membrane potential-sensitive dyes: advantages and potential problems.
Journal of neuroscience methods 2005;149(2):172-7.
2005: Sarah C R Lummis; Darren L Beene; Lori W Lee; Henry A Lester; R William Broadhurst; Dennis A Dougherty
Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.
Nature 2005;438(7065):248-52.
2005: Sarah C R Lummis; Darren L Beene; Neil J Harrison; Henry A Lester; Dennis A Dougherty
A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor.
Chemistry & biology 2005;12(9):993-7.
2005: Alex J Laude; Stephen C Tovey; Skarlatos G Dedos; Barry V L Potter; Sarah C R Lummis; Colin W Taylor
Rapid functional assays of recombinant IP3 receptors.
Cell calcium 2005;38(1):45-51.
2005: Andrew J Thompson; Kerry L Price; David C Reeves; S Ling Chan; Pak-Lee Chau; Sarah C R Lummis
Locating an antagonist in the 5-HT3 receptor binding site using modeling and radioligand binding.
The Journal of biological chemistry 2005;280(21):20476-82.
2004: Darren L Beene; Kerry L Price; Henry A Lester; Dennis A Dougherty; Sarah C R Lummis
Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(41):9097-104.
2004: Sarah C R Lummis
The transmembrane domain of the 5-HT3 receptor: its role in selectivity and gating.
Biochemical Society transactions 2004;32(Pt3):535-9.
2004: John O'Brien; Sarah C R Lummis
Biolistic and diolistic transfection: using the gene gun to deliver DNA and lipophilic dyes into mammalian cells.
Methods (San Diego, Calif.) 2004;33(2):121-5.
2004: Kerry L Price; Sarah C R Lummis
The role of tyrosine residues in the extracellular domain of the 5-hydroxytryptamine3 receptor.
The Journal of biological chemistry 2004;279(22):23294-301.
2003: Andrew J Thompson; Sarah C R Lummis
A single ring of charged amino acids at one end of the pore can control ion selectivity in the 5-HT3 receptor.
British journal of pharmacology 2003;140(2):359-65.
2003: David C Reeves; Muhammed Sayed; Pak-Lee Chau; Kerry L Price; Sarah C R Lummis
Prediction of 5-HT3 receptor agonist-binding residues using homology modeling.
Biophysical journal 2003;84(4):2338-44.
2002: John O'Brien; Sarah C R Lummis
An improved method of preparing microcarriers for biolistic transfection.
Brain research. Brain research protocols 2002;10(1):12-5.
2002: Avron D Spier; Sarah C R Lummis
Immunological characterization of 5-HT3 receptor transmembrane topology.
Journal of molecular neuroscience : MN 2002;18(3):169-78.
2002: L John Greenfield; Shahid H Zaman; Margaret L Sutherland; Sarah C R Lummis; María-Isabel Niemeyer; Eric A Barnard; Robert L Macdonald
Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement.
Neuropharmacology 2002;42(4):502-21.
2002: Sarah C R Lummis; Elizabeth J Fletcher; Tim Green
Identification of a new site in the S1 ligand binding region of the NMDA receptor NR2A subunit involved in receptor activation by glutamate.
Neuropharmacology 2002;42(4):437-43.
2002: David C Reeves; Sarah C R Lummis
The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review).
Molecular membrane biology 2002;19(1):11-26.
2001: J A O'Brien; M Holt; G Whiteside; Sarah C R Lummis; M H Hastings
Modifications to the hand-held Gene Gun: improvements for in vitro biolistic transfection of organotypic neuronal tissue.
Journal of neuroscience methods 2001;112(1):57-64.
2001: David C Reeves; E N Goren; Myles H Akabas; Sarah C R Lummis
Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis.
The Journal of biological chemistry 2001;276(45):42035-42.
2001: CM Deane; Sarah C R Lummis
The role and predicted propensity of conserved proline residues in the 5-HT3 receptor.
The Journal of biological chemistry 2001;276(41):37962-6.
2001: M I Niemeyer; Sarah C R Lummis
The role of the agonist binding site in Ca(2+) inhibition of the recombinant 5-HT(3A) receptor.
European journal of pharmacology 2001;428(2):153-61.
2001: Martin Gunthorpe; Sarah C R Lummis
Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily.
The Journal of biological chemistry 2001;276(24):10977-83.
2001: Martin Gunthorpe; Sarah C R Lummis
Conversion of the ion selectivity of the 5-HT(3a) receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily.
The Journal of biological chemistry 2001;276(14):10977-83.
2000: Jamie I Vandenberg; Sarah C R Lummis
Ion channels--a plethora of pharmaceutical targets.
Trends in pharmacological sciences 2000;21(11):409-10.
2000: SV Nayak; P Rondé; Avron D Spier; Sarah C R Lummis; Robert A Nichols
Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals.
Neuropharmacology 2000;39(13):2681-90.
2000: P C Hubbard; A J Thompson; Sarah C R Lummis
Functional differences between splice variants of the murine 5-HT(3A) receptor: possible role for phosphorylation.
Brain research. Molecular brain research 2000;81(1-2):101-8.
2000: P C Hubbard; Sarah C R Lummis
Zn(2+) enhancement of the recombinant 5-HT(3) receptor is modulated by divalent cations.
European journal of pharmacology 2000;394(2-3):189-97.
2000: Avron D Spier; Sarah C R Lummis
The role of tryptophan residues in the 5-Hydroxytryptamine(3) receptor ligand binding domain.
The Journal of biological chemistry 2000;275(8):5620-5.
2000: Martin Gunthorpe; J A Peters; Catherine H Gill; J J Lambert; Sarah C R Lummis
The 4'lysine in the putative channel lining domain affects desensitization but not the single-channel conductance of recombinant homomeric 5-HT3A receptors.
The Journal of physiology 2000;522 Pt 2():187-98.
1999: Martin Gunthorpe; Sarah C R Lummis
Diltiazem causes open channel block of recombinant 5-HT3 receptors.
The Journal of physiology 1999;519 Pt 3():713-22.
1999: Avron D Spier; G Wotherspoon; SV Nayak; Robert A Nichols; J V Priestley; Sarah C R Lummis
Antibodies against the extracellular domain of the 5-HT3 receptor label both native and recombinant receptors.
Brain research. Molecular brain research 1999;67(2):221-30.
1999: SV Nayak; P Rondé; Avron D Spier; Sarah C R Lummis; Robert A Nichols
Calcium changes induced by presynaptic 5-hydroxytryptamine-3 serotonin receptors on isolated terminals from various regions of the rat brain.
Neuroscience 1999;91(1):107-17.
1998: Johannes van Hooft; Avron D Spier; Jerrel L Yakel; Sarah C R Lummis; Henk P M Vijverberg
Promiscuous coassembly of serotonin 5-HT3 and nicotinic alpha4 receptor subunits into Ca(2+)-permeable ion channels.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(19):11456-61.
1998: M I Niemeyer; Sarah C R Lummis
Different efficacy of specific agonists at 5-HT3 receptor splice variants: the role of the extra six amino acid segment.
British journal of pharmacology 1998;123(4):661-6.
1997: Sarah C R Lummis; J Baker
Radioligand binding and photoaffinity labelling studies show a direct interaction of phenothiazines at 5-HT3 receptors.
Neuropharmacology 1997;36(4-5):665-70.
1996: A C Hargreaves; Martin Gunthorpe; Colin W Taylor; Sarah C R Lummis
Direct inhibition of 5-hydroxytryptamine3 receptors by antagonists of L-type Ca2+ channels.
Molecular pharmacology 1996;50(5):1284-94.
1995: Steven Buckingham; M L Balk; Sarah C R Lummis; P Jewess; David B Sattelle
Actions of nitromethylenes on an alpha-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor.
Neuropharmacology 1995;34(6):591-7.
1994: A C Hargreaves; Sarah C R Lummis; Colin W Taylor
Ca2+ permeability of cloned and native 5-hydroxytryptamine type 3 receptors.
Molecular pharmacology 1994;46(6):1120-8.
1994: M I Sepúlveda; J Baker; Sarah C R Lummis
Chlorpromazine and QX222 block 5-HT3 receptors in N1E-115 neuroblastoma cells.
Neuropharmacology 1994;33(3-4):493-9.
1993: Sarah C R Lummis; M I Sepúlveda; G J Kilpatrick; J Baker
Characterization of [3H]meta-chlorophenylbiguanide binding to 5-HT3 receptors in N1E-115 neuroblastoma cells.
European journal of pharmacology 1993;243(1):7-11.
1993: Steven Buckingham; Sarah C R Lummis; M L Balk; M Schroeder; David B Sattelle
Actions of vesamicol on an alpha-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor.
The Journal of experimental biology 1993;182():255-64.
1992: F G Boess; Sarah C R Lummis; Ian L Martin
Molecular properties of 5-hydroxytryptamine3 receptor-type binding sites purified from NG108-15 cells.
Journal of neurochemistry 1992;59(5):1692-701.
1992: F G Boess; M I Sepúlveda; Sarah C R Lummis; Ian L Martin
5-HT3 receptors in NG108-15 neuroblastoma x glioma cells: effect of the novel agonist 1-(m-chlorophenyl)-biguanide.
Neuropharmacology 1992;31(6):561-4.
1992: Sarah C R Lummis; Steven Buckingham; M L Balk; C W Holyoke; David B Sattelle
Actions of a series of bisquaternary compounds on nicotinic acetylcholine receptors in insects: ligand binding and electrophysiological studies.
Neuropharmacology 1992;31(4):379-82.
1992: Sarah C R Lummis; Ian L Martin
Solubilization, purification, and functional reconstitution of 5-hydroxytryptamine3 receptors from N1E-115 neuroblastoma cells.
Molecular pharmacology 1992;41(1):18-23.
1991: M I Sepúlveda; Sarah C R Lummis; Ian L Martin
The agonist properties of m-chlorophenylbiguanide and 2-methyl-5-hydroxytryptamine on 5-HT3 receptors in N1E-115 neuroblastoma cells.
British journal of pharmacology 1991;104(2):536-40.
1991: David B Sattelle; Sarah C R Lummis; J F Wong; James J Rauh
Pharmacology of insect GABA receptors.
Neurochemical research 1991;16(3):363-74.
1990: Sarah C R Lummis; Ian L Martin
Characterization of soluble 5-hydroxytryptamine3 receptors from N1E115 neuroblastoma cells.
Biochemical Society transactions 1990;18(5):1027-8.
1990: Sarah C R Lummis; M Nielsen; G J Kilpatrick; Ian L Martin
Target size of 5-HT3 receptors in N1E-115 neuroblastoma cells and rat brain.
European journal of pharmacology 1990;189(2-3):229-32.
1990: Sarah C R Lummis; G J Kilpatrick; Ian L Martin
Characterization of 5-HT3 receptors in intact N1E-115 neuroblastoma cells.
European journal of pharmacology 1990;189(2-3):223-7.
1990: James J Rauh; Sarah C R Lummis; D B Sattelle
Pharmacological and biochemical properties of insect GABA receptors.
Trends in pharmacological sciences 1990;11(8):325-9.
1990: Sarah C R Lummis; Steven Buckingham; James J Rauh; David B Sattelle
Blocking actions of heptachlor at an insect central nervous system GABA receptor.
Proceedings of the Royal Society of London. Series B, Containing papers of a Biological character. Royal Society (Great Britain) 1990;240(1297):97-106.
1990: Sarah C R Lummis
GABA receptors in insects.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1990;95(1):1-8.
1989: K A Wafford; Sarah C R Lummis; David B Sattelle
Block of an insect central nervous system GABA receptor by cyclodiene and cyclohexane insecticides.
Proceedings of the Royal Society of London. Series B, Containing papers of a Biological character. Royal Society (Great Britain) 1989;237(1286):53-61.
1989: Sarah C R Lummis; David B Sattelle
Insect nervous system [(3)H]saxitoxin binding sites: characterization and target size.
Neurochemistry international 1989;15(4):391-5.
1988: R D Pinnock; Sarah C R Lummis; V A Chiappinelli; David B Sattelle
Kappa-bungarotoxin blocks an alpha-bungarotoxin-sensitive nicotinic receptor in the insect central nervous system.
Brain research 1988;458(1):45-52.
1988: Sarah C R Lummis; J C Ellory; David B Sattelle
The cross-linking reagent dimethyl suberimate modifies the target size of an insect nervous system nicotinic acetylcholine receptor.
Neuroscience letters 1988;87(1-2):145-50.
1986: Sarah C R Lummis; David B Sattelle
Binding sites for [(3)H]GABA, [(3)H]flunitrazepam and [(35)S]TBPS in insect CNS.
Neurochemistry international 1986;9(2):287-93.