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Leif Lund

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Birgitte Rønø; Leif R Lund; Lars Henning Engelholm; Andreas Hald
Gender affects skin wound healing in plasminogen deficient mice.
Andreas Hald; Ole Didrik Laerum; Leif R Lund; Rasmus Baadsgaard Maerkedahl; Kristoffer Lihme Egerod; Hanne Eickhardt; Lars Henning Engelholm; Christina Winther Feldborg; Birgitte Rønø
Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner.
Elisabeth P Cramer; Lars H Engelholm; A Glenthøj; Mattias Häger; Anna Juncker-Jensen; Ole D Laerum; Leif R Lund; Eric Santoni-Rugiu; Jack B Cowland; Niels Borregaard
No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer.

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2013: Birgitte Rønø; Leif R Lund; Lars Henning Engelholm; Andreas Hald
Gender affects skin wound healing in plasminogen deficient mice.
PloS one 2013;8(3):e59942.
2012: Andreas Hald; Ole Didrik Laerum; Leif R Lund; Rasmus Baadsgaard Maerkedahl; Kristoffer Lihme Egerod; Hanne Eickhardt; Lars Henning Engelholm; Christina Winther Feldborg; Birgitte Rønø
Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(11):4445-57.
2012: Elisabeth P Cramer; Lars H Engelholm; A Glenthøj; Mattias Häger; Anna Juncker-Jensen; Ole D Laerum; Leif R Lund; Eric Santoni-Rugiu; Jack B Cowland; Niels Borregaard
No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer.
PloS one 2012;7(6):e39646.
2012: Andreas Hald; Leif R Lund; Birgitte Rønø; Kristoffer Lihme Egerod
LPS counter regulates RNA expression of extracellular proteases and their inhibitors in murine macrophages.
Mediators of inflammation 2012;2012():157894.
2011: Ida Katrine Lund; Boye Nielsen; John Rømer; Birgitte Rønø; Kasper Almholt; Ib J Christensen; Kirsty A Green; Andreas Hald; Martin Illemann; Leif R Lund
Concomitant lack of MMP9 and uPA disturbs physiological tissue remodeling.
Developmental biology 2011;358(1):56-67.
2011: Andreas Hald; Birgitte Rønø; Maria C Melander; Ming Ding; Susanne Holck; Leif R Lund
MMP9 is protective against lethal inflammatory mass lesions in the mouse colon.
Disease models & mechanisms 2011;4(2):212-27.
2011: Anna Juncker-Jensen; Leif R Lund
Phenotypic overlap between MMP-13 and the plasminogen activation system during wound healing in mice.
PloS one 2011;6(2):e16954.
2010: Signe Frøssing; Birgitte Rønø; Andreas Hald; John Rømer; Leif R Lund
Skin wound healing in MMP2-deficient and MMP2 / plasminogen double-deficient mice.
Experimental dermatology 2010;19(8):e234-40.
2010: Warner Alpízar-Alpízar; Boye Nielsen; Rafaela Sierra; Martin Illemann; Jose A Ramírez; Adriana Arias; Sundry Durán; Arne Skarstein; Kjell Ovrebo; Leif R Lund; Ole D Laerum
Urokinase plasminogen activator receptor is expressed in invasive cells in gastric carcinomas from high- and low-risk countries.
International journal of cancer. Journal international du cancer 2010;126(2):405-15.
2010: Annika Jögi; Birgitte Rønø; Ida K Lund; Boye Nielsen; Michael Ploug; Gunilla Høyer-Hansen; John Rømer; Leif R Lund
Neutralisation of uPA with a monoclonal antibody reduces plasmin formation and delays skin wound healing in tPA-deficient mice.
PloS one 2010;5(9):e12746.
2010: Françoise Bruyère; Laurence Melen-Lamalle; Silvia Blacher; Benoît Detry; Anne Masset; Julie Lecomte; Vincent Lambert; Catherine Maillard; Gunilla Høyer-Hansen; Leif R Lund; Jean-Michel Foidart; Agnès Noël
Does plasminogen activator inhibitor-1 drive lymphangiogenesis?
PloS one 2010;5(3):e9653.
2009: Warner Alpízar-Alpízar; Ole Didrik Laerum; Martin Illemann; José A Ramírez; Adriana Arias; Wendy Malespín-Bendaña; Vanessa Ramírez; Leif R Lund; Niels Borregaard; Boye Nielsen
Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori.
Virchows Archiv : an international journal of pathology 2009;455(3):225-33.
2009: Ulrik Doehn; Camilla Hauge; Scott R Frank; Claus J Jensen; Katarzyna Duda; Jakob V Nielsen; Michael S Cohen; Jens V Johansen; Benny R Winther; Leif R Lund; Ole Winther; Jack Taunton; Steen H Hansen; Morten Frödin
RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.
Molecular cell 2009;35(4):511-22.
2009: Anna Juncker-Jensen; John Rømer; Caroline J Pennington; Leif R Lund; Kasper Almholt
Spontaneous metastasis in matrix metalloproteinase 3-deficient mice.
Molecular carcinogenesis 2009;48(7):618-25.
2009: Martin Illemann; Nigel Bird; Ali Majeed; Ole D Laerum; Leif R Lund; Keld Danø; Boye Nielsen
Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases.
International journal of cancer. Journal international du cancer 2009;124(8):1860-70.
2008: Ida K Lund; Annika Jögi; Birgitte Rønø; Morten G Rasch; Leif R Lund; Kasper Almholt; Henrik Gårdsvoll; Niels Behrendt; John Rømer; Gunilla Høyer-Hansen
Antibody-mediated targeting of the urokinase-type plasminogen activator proteolytic function neutralizes fibrinolysis in vivo.
The Journal of biological chemistry 2008;283(47):32506-15.
2008: Kasper Almholt; Anna Juncker-Jensen; Ole Didrik Laerum; Keld Danø; Morten Johnsen; Leif R Lund; John Rømer
Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model.
Molecular cancer therapeutics 2008;7(9):2758-67.
2008: Kirsty A Green; Kasper Almholt; Michael Ploug; Birgitte Rønø; Francis J Castellino; Morten Johnsen; Thomas H Bugge; John Rømer; Leif R Lund
Profibrinolytic effects of metalloproteinases during skin wound healing in the absence of plasminogen.
The Journal of investigative dermatology 2008;128(8):2092-101.
2008: Signe Ingvarsen; Daniel H Madsen; Thore Hillig; Leif R Lund; Kenn Holmbeck; Niels Behrendt; Lars H Engelholm
Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells.
Biological chemistry 2008;389(7):943-53.
2008: Silvia Blacher; Maud Jost; L Melen-Lamalle; Leif R Lund; J Romer; Jean-Michel Foidart; Agnès Noël
Quantification of in vivo tumor invasion and vascularization by computerized image analysis.
Microvascular research 2008;75(2):169-78.
2008: Boye Nielsen; Mikala Egeblad; Fritz Rank; Hanne A Askautrud; Caroline J Pennington; Tanja X Pedersen; Ib J Christensen; Dylan R Edwards; Zena Werb; Leif R Lund
Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression.
PloS one 2008;3(8):e2959.
2007: Annika Jögi; Jesper Pass; Gunilla Høyer-Hansen; Leif R Lund; Boye Nielsen; Keld Danø; John Rømer
Systemic administration of anti-urokinase plasminogen activator receptor monoclonal antibodies induces hepatic fibrin deposition in tissue-type plasminogen activator deficient mice.
Journal of thrombosis and haemostasis : JTH 2007;5(9):1936-44.
2007: Jesper Pass; Annika Jögi; Ida Katrine Lund; Birgitte Rønø; Morten G Rasch; Henrik Gårdsvoll; Leif R Lund; Michael Ploug; John Rømer; Keld Danø; Gunilla Høyer-Hansen
Murine monoclonal antibodies against murine uPA receptor produced in gene-deficient mice: inhibitory effects on receptor-mediated uPA activity in vitro and in vivo.
Thrombosis and haemostasis 2007;97(6):1013-22.
2007: Boye Nielsen; Fritz Rank; Martin Illemann; Leif R Lund; Keld Danø
Stromal cells associated with early invasive foci in human mammary ductal carcinoma in situ coexpress urokinase and urokinase receptor.
International journal of cancer. Journal international du cancer 2007;120(10):2086-95.
2007: Kasper Almholt; Kirsty A Green; Anna Juncker-Jensen; Boye Nielsen; Leif R Lund; John Rømer
Extracellular proteolysis in transgenic mouse models of breast cancer.
Journal of mammary gland biology and neoplasia 2007;12(1):83-97.
2007: Patrik Wahlberg; Ida Bodén; Josefin Paulsson; Leif R Lund; Kui Liu; Tor Ny
Functional corpora lutea are formed in matrix metalloproteinase inhibitor-treated plasminogen-deficient mice.
Endocrinology 2007;148(3):1226-34.
2006: Kirsty A Green; Boye Nielsen; Francis J Castellino; John Rømer; Leif R Lund
Lack of plasminogen leads to milk stasis and premature mammary gland involution during lactation.
Developmental biology 2006;299(1):164-75.
2006: Anders Stegmann; Morten Hansen; Yulan Wang; Janus B Larsen; Leif R Lund; Léa Ritié; Jeremy K Nicholson; Bjørn Quistorff; Patricia Simon-Assmann; Jesper T Troelsen; Jørgen Olsen
Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation.
Physiological genomics 2006;27(2):141-55.
2006: Kui Liu; Patrik Wahlberg; Göran Leonardsson; Anna-Carin Hägglund; Annelii Ny; Ida Bodén; Carin Wibom; Leif R Lund; Tor Ny
Successful ovulation in plasminogen-deficient mice treated with the broad-spectrum matrix metalloproteinase inhibitor galardin.
Developmental biology 2006;295(2):615-22.
2006: Leif R Lund; Kirsty A Green; Allart A Stoop; Michael Ploug; Kasper Almholt; Jennifer Lilla; Boye Nielsen; Ib Jarle Christensen; Charles S Craik; Zena Werb; Keld Danø; John Rømer
Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice.
The EMBO journal 2006;25(12):2686-97.
2006: Martin Illemann; Nigel Bird; Ali Majeed; Maxwell Sehested; Ole D Laerum; Leif R Lund; Keld Danø; Boye Nielsen
MMP-9 is differentially expressed in primary human colorectal adenocarcinomas and their metastases.
Molecular cancer research : MCR 2006;4(5):293-302.
2006: Sarah Porter; Paul Span; Fred C G J Sweep; Vivianne C G Tjan-Heijnen; Caroline J Pennington; Tanja Xenia Pedersen; Morten Johnsen; Leif R Lund; John Rømer; Dylan R Edwards
ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma.
International journal of cancer. Journal international du cancer 2006;118(5):1241-7.
2005: Kirsty A Green; Leif R Lund
ECM degrading proteases and tissue remodelling in the mammary gland.
BioEssays : news and reviews in molecular, cellular and developmental biology 2005;27(9):894-903.
2005: Alejandro Curino; Lars H Engelholm; Susan S Yamada; Kenn Holmbeck; Leif R Lund; Alfredo A Molinolo; Niels Behrendt; Boye Nielsen; Thomas H Bugge
Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy.
The Journal of cell biology 2005;169(6):977-85.
2005: Keld Danø; Niels Behrendt; Gunilla Høyer-Hansen; Morten Johnsen; Leif R Lund; Michael Ploug; John Rømer
Plasminogen activation and cancer.
Thrombosis and haemostasis 2005;93(4):676-81.
2005: Kasper Almholt; Leif R Lund; Jørgen Rygaard; Boye Nielsen; Keld Danø; John Rømer; Morten Johnsen
Reduced metastasis of transgenic mammary cancer in urokinase-deficient mice.
International journal of cancer. Journal international du cancer 2005;113(4):525-32.
2004: Martin Illemann; Ulla Hansen; Hans Jørgen Nielsen; Peter A Andreasen; Gunilla Høyer-Hansen; Leif R Lund; Keld Danø; Boye Nielsen
Leading-edge myofibroblasts in human colon cancer express plasminogen activator inhibitor-1.
American journal of clinical pathology 2004;122(2):256-65.
2004: Line V Hansen; Henrik Gårdsvoll; Boye Nielsen; Leif R Lund; Keld Danø; Ole N Jensen; Michael Ploug
Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor.
The Biochemical journal 2004;380(Pt 3):845-57.
2004: Robert Blakytny; Anna Ludlow; Gail E M Martin; Grenham Ireland; Leif R Lund; Mark W J Ferguson; Georg Brunner
Latent TGF-beta1 activation by platelets.
Journal of cellular physiology 2004;199(1):67-76.
2003: Catherine Vaillant; Claire Meissirel; Mireille Mutin; Marie-Françoise Belin; Leif R Lund; Nicole Thomasset
MMP-9 deficiency affects axonal outgrowth, migration, and apoptosis in the developing cerebellum.
Molecular and cellular neurosciences 2003;24(2):395-408.
2003: Bryony S Wiseman; Mark D Sternlicht; Leif R Lund; Caroline M Alexander; Joni Mott; Mina J Bissell; Paul Soloway; Shigeyoshi Itohara; Zena Werb
Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis.
The Journal of cell biology 2003;162(6):1123-33.
2003: Jesper Pass; Henrik Gårdsvoll; Leif R Lund; Keld Danø; Gunilla Høyer-Hansen
Generation of antibodies to the urokinase receptor (uPAR) by DNA immunization of uPAR knockout mice: membrane-bound uPAR is not required for an antibody response.
Scandinavian journal of immunology 2003;58(3):298-305.
2003: Helene Solberg; Julie Rinkenberger; Keld Danø; Zena Werb; Leif R Lund
A functional overlap of plasminogen and MMPs regulates vascularization during placental development.
Development (Cambridge, England) 2003;130(18):4439-50.
2003: Tanja Xenia Pedersen; Chidchanop Leethanakul; Vyomesh Patel; David J Mitola; Leif R Lund; Keld Danø; Morten Johnsen; J Silvio Gutkind; Thomas H Bugge
Laser capture microdissection-based in vivo genomic profiling of wound keratinocytes identifies similarities and differences to squamous cell carcinoma.
Oncogene 2003;22(25):3964-76.
2001: Lars H Engelholm; Boye Nielsen; Sarah Netzel-Arnett; Helene Solberg; X D Chen; J M Lopez Garcia; Carlos Lopez-Otin; M F Young; Henning Birkedal-Hansen; Keld Danø; Leif R Lund; Niels Behrendt; Thomas H Bugge
The urokinase plasminogen activator receptor-associated protein/endo180 is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis.
Laboratory investigation; a journal of technical methods and pathology 2001;81(10):1403-14.
2001: Boye Nielsen; Fritz Rank; J M López; M Balbin; F Vizoso; Leif R Lund; Keld Danø; C López-Otín
Collagenase-3 expression in breast myofibroblasts as a molecular marker of transition of ductal carcinoma in situ lesions to invasive ductal carcinomas.
Cancer research 2001;61(19):7091-100.
2001: Boye Nielsen; Leif R Lund; I J Christensen; Morten Johnsen; Pernille Autzen Usher; L Wulf-Andersen; Thomas L Frandsen; K Danø; H J Gundersen
A precise and efficient stereological method for determining murine lung metastasis volumes.
The American journal of pathology 2001;158(6):1997-2003.
2001: Brigitte Lelongt; S Bengatta; M Delauche; Leif R Lund; Z Werb; Pierre M Ronco
Matrix metalloproteinase 9 protects mice from anti-glomerular basement membrane nephritis through its fibrinolytic activity.
The Journal of experimental medicine 2001;193(7):793-802.
2001: John Rømer; C Pyke; Leif R Lund; Elisabeth Ralfkiaer; Keld Danø
Cancer cell expression of urokinase-type plasminogen activator receptor mRNA in squamous cell carcinomas of the skin.
The Journal of investigative dermatology 2001;116(3):353-8.
2001: Khalid Bajou; Véronique Masson; Robert D Gerard; P M Schmitt; V Albert; Michael Praus; Leif R Lund; Thomas L Frandsen; Nils Brunner; K Dano; Norbert E Fusenig; UH Weidle; G Carmeliet; D Loskutoff; Désiré Collen; Peter Carmeliet; Jean-Michel Foidart; Agnès Noël
The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies.
The Journal of cell biology 2001;152(4):777-84.
2001: Helene Solberg; Michael Ploug; Gunilla Høyer-Hansen; Boye Nielsen; Leif R Lund
The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(2):237-46.
2000: Leif R Lund; SF Bjørn; Mark D Sternlicht; Boye Nielsen; Helene Solberg; Pernille Autzen Usher; Ruth Osterby; Ib Jarle Christensen; Ross W Stephens; Thomas H Bugge; Keld Danø; Zena Werb
Lactational competence and involution of the mouse mammary gland require plasminogen.
Development (Cambridge, England) 2000;127(20):4481-92.
2000: SF Bjørn; N Hastrup; J F Larsen; Leif R Lund; C Pyke
Messenger RNA for membrane-type 2 matrix metalloproteinase, MT2-MMP, is expressed in human placenta of first trimester.
Placenta 2000;21(2-3):170-6.
2000: Karin List; Ole N Jensen; Thomas H Bugge; Leif R Lund; Michael Ploug; Keld Danø; Niels Behrendt
Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice.
Biochemistry 2000;39(3):508-15.
1999: Leif R Lund; J Romer; Thomas H Bugge; Boye Nielsen; Thomas L Frandsen; J L Degen; Ross W Stephens; Keld Danø
Functional overlap between two classes of matrix-degrading proteases in wound healing.
The EMBO journal 1999;18(17):4645-56.
1999: Keld Danø; John Rømer; Boye Nielsen; SF Bjørn; C Pyke; Jørgen Rygaard; Leif R Lund
Cancer invasion and tissue remodeling--cooperation of protease systems and cell types.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1999;107(1):120-7.
1998: Morten Johnsen; Leif R Lund; John Rømer; Kasper Almholt; Keld Danø
Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation.
Current opinion in cell biology 1998;10(5):667-71.
1998: Nicole Thomasset; A Lochter; CJ Sympson; Leif R Lund; D R Williams; O Behrendtsen; Zena Werb; Mina J Bissell
Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development.
The American journal of pathology 1998;153(2):457-67.
1998: Thomas H Bugge; Leif R Lund; K K Kombrinck; Boye Nielsen; K Holmbäck; Angela F Drew; Matthew J Flick; David P Witte; Keld Danø; Jay L Degen
Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice.
Oncogene 1998;16(24):3097-104.
1997: John Rømer; Leif R Lund; K Danø
Healing hormones.
Nature medicine 1997;3(11):1195-6.
1997: SF Bjørn; N Hastrup; Leif R Lund; Keld Danø; J F Larsen; C Pyke
Co-ordinated expression of MMP-2 and its putative activator, MT1-MMP, in human placentation.
Molecular human reproduction 1997;3(8):713-23.
1996: John Rømer; Thomas H Bugge; C Pyke; Leif R Lund; M J Flick; Jay L Degen; Keld Danø
Plasminogen and wound healing.
Nature medicine 1996;2(7):725.
1996: Zena Werb; CJ Sympson; C M Alexander; Nicole Thomasset; Leif R Lund; A MacAuley; J Ashkenas; Mina J Bissell
Extracellular matrix remodeling and the regulation of epithelial-stromal interactions during differentiation and involution.
Kidney international. Supplement 1996;54():S68-74.
1996: Leif R Lund
Expression of urokinase-type plasminogen activator, its receptor and type-1 plasminogen activator inhibitor is differently regulated by inhibitors of protein synthesis in human cancer cell lines.
FEBS letters 1996;383(3):139-44.
1996: Leif R Lund; J Eriksen; Elisabeth Ralfkiaer; John Rømer
Differential expression of urokinase-type plasminogen activator, its receptor, and inhibitors in mouse skin after exposure to a tumor-promoting phorbol ester.
The Journal of investigative dermatology 1996;106(4):622-30.
1996: J Romer; Thomas H Bugge; C Pyke; Leif R Lund; M J Flick; Jay L Degen; K Dano
Impaired wound healing in mice with a disrupted plasminogen gene.
Nature medicine 1996;2(3):287-92.
1996: Leif R Lund; John Rømer; Nicole Thomasset; H Solberg; C Pyke; Mina J Bissell; K Danø; Zena Werb
Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.
Development (Cambridge, England) 1996;122(1):181-93.
1995: Leif R Lund; V Ellis; E Rønne; C Pyke; Keld Danø
Transcriptional and post-transcriptional regulation of the receptor for urokinase-type plasminogen activator by cytokines and tumour promoters in the human lung carcinoma cell line A549.
The Biochemical journal 1995;310 ( Pt 1)():345-52.
1995: E Feiken; John Rømer; J Eriksen; Leif R Lund
Neutrophils express tumor necrosis factor-alpha during mouse skin wound healing.
The Journal of investigative dermatology 1995;105(1):120-3.
1994: C Pyke; John Rømer; P Kallunki; Leif R Lund; Elisabeth Ralfkiaer; Keld Danø; K Tryggvason
The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers.
The American journal of pathology 1994;145(4):782-91.
1994: John Rømer; C Pyke; Leif R Lund; J Eriksen; P Kristensen; E Rønne; Gunilla Høyer-Hansen; Keld Danø; Nils Brünner
Expression of uPA and its receptor by both neoplastic and stromal cells during xenograft invasion.
International journal of cancer. Journal international du cancer 1994;57(4):553-60.
1994: John Rømer; Leif R Lund; J Eriksen; C Pyke; P Kristensen; Keld Danø
The receptor for urokinase-type plasminogen activator is expressed by keratinocytes at the leading edge during re-epithelialization of mouse skin wounds.
The Journal of investigative dermatology 1994;102(4):519-22.
1994: J Skouv; P O Jensen; J Forchhammer; J K Larsen; Leif R Lund
Tumor-promoting phorbol ester transiently down-modulates the p53 level and blocks the cell cycle.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(3):329-40.
1993: C Pyke; J Eriksen; H Solberg; Boye Nielsen; P Kristensen; Leif R Lund; Keld Danø
An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator.
FEBS letters 1993;326(1-3):69-74.
1992: Gunilla Høyer-Hansen; E Rønne; H Solberg; Niels Behrendt; Michael Ploug; Leif R Lund; V Ellis; Keld Danø
Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain.
The Journal of biological chemistry 1992;267(25):18224-9.
1992: Leif R Lund; Keld Danø
Okadaic acid strongly increases gene transcription, mRNA and protein level for the urokinase receptor in human A549 cells.
FEBS letters 1992;298(2-3):177-81.
1991: John Rømer; Leif R Lund; J Eriksen; Elisabeth Ralfkiaer; R Zeheb; Thomas D Gelehrter; Keld Danø; P Kristensen
Differential expression of urokinase-type plasminogen activator and its type-1 inhibitor during healing of mouse skin wounds.
The Journal of investigative dermatology 1991;97(5):803-11.
1991: Leif R Lund; John Rømer; E Rønne; V Ellis; F Blasi; Keld Danø
Urokinase-receptor biosynthesis, mRNA level and gene transcription are increased by transforming growth factor beta 1 in human A549 lung carcinoma cells.
The EMBO journal 1991;10(11):3399-407.
1991: Leif R Lund; E Rønne; A L Roldan; Niels Behrendt; John Rømer; F Blasi; Keld Danø
Urokinase receptor mRNA level and gene transcription are strongly and rapidly increased by phorbol myristate acetate in human monocyte-like U937 cells.
The Journal of biological chemistry 1991;266(8):5177-81.
1991: J Grøndahl-Hansen; E Ralfkiaer; L T Kirkeby; P Kristensen; Leif R Lund; K Danø
Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans.
The American journal of pathology 1991;138(1):111-7.
1990: F Blasi; Niels Behrendt; M V Cubellis; V Ellis; Leif R Lund; M T Masucci; L B Møller; D P Olson; Nina Pedersen; Michael Ploug
The urokinase receptor and regulation of cell surface plasminogen activation.
Cell differentiation and development : the official journal of the International Society of Developmental Biologists 1990;32(3):247-53.
1990: A L Roldan; M V Cubellis; M T Masucci; Niels Behrendt; Leif R Lund; Keld Danø; Ettore Appella; F Blasi
Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.
The EMBO journal 1990;9(2):467-74.
1990: P A Andreasen; Birgitte Georg; Leif R Lund; A Riccio; S N Stacey
Plasminogen activator inhibitors: hormonally regulated serpins.
Molecular and cellular endocrinology 1990;68(1):1-19.
1990: P Kristensen; C Pyke; Leif R Lund; P A Andreasen; Keld Danø
Plasminogen activator inhibitor-type 1 in Lewis lung carcinoma.
Histochemistry 1990;93(6):559-66.
1989: J Grøndahl-Hansen; L T Kirkeby; E Ralfkiaer; P Kristensen; Leif R Lund; K Danø
Urokinase-type plasminogen activator in endothelial cells during acute inflammation of the appendix.
The American journal of pathology 1989;135(4):631-6.
1989: Birgitte Georg; E Helseth; Leif R Lund; T Skandsen; A Riccio; Keld Danø; G Unsgaard; P A Andreasen
Tumor necrosis factor-alpha regulates mRNA for urokinase-type plasminogen activator and type-1 plasminogen activator inhibitor in human neoplastic cell lines.
Molecular and cellular endocrinology 1989;61(1):87-96.
1988: Leif R Lund; Birgitte Georg; L S Nielsen; Michael Mayer; Keld Danø; P A Andreasen
Plasminogen activator inhibitor type 1: cell-specific and differentiation-induced expression and regulation in human cell lines, as determined by enzyme-linked immunosorbent assay.
Molecular and cellular endocrinology 1988;60(1):43-53.
1988: Michael Mayer; Leif R Lund; A Riccio; J Skouv; L S Nielsen; S N Stacey; Keld Danø; P A Andreasen
Plasminogen activator inhibitor type-1 protein, mRNA and gene transcription are increased by phorbol esters in human rhabdomyosarcoma cells.
The Journal of biological chemistry 1988;263(30):15688-93.
1988: E Helseth; A Dalen; G Unsgaard; T Skandsen; J Grøndahl-Hansen; Leif R Lund
Transforming growth factor-beta 1 is a potent inducer of plasminogen activator inhibitor type-1 in human glioblastoma and carcinoma cell lines.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1988;96(9):845-9.
1988: J Grøndahl-Hansen; Leif R Lund; Elisabeth Ralfkiaer; V Ottevanger; Keld Danø
Urokinase- and tissue-type plasminogen activators in keratinocytes during wound reepithelialization in vivo.
The Journal of investigative dermatology 1988;90(6):790-5.
1987: P A Andreasen; C Pyke; A Riccio; P Kristensen; L S Nielsen; Leif R Lund; F Blasi; Keld Danø
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