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Gregory Barsh
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16
Ollmann, MM
14
Gunn, Teresa
11
Gantz, Ira
10
Kaelin, Christopher
9
Millhauser, Glenn
9
Lu, Xin Yun
7
Hearing, Vincent
7
Wilson, BD
7
Kerns, Julie
7
He, Lin
6
Candille, Sophie
6
Clément, Karine
6
Thompson, Darren
6
Watson Jr, Stanley
6
Schwartz, Michael
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All Publications
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2009: Van Raamsdonk Catherine D; Barsh Gregory S; Wakamatsu Kazumasa; Ito Shosuke
Independent regulation of hair and skin color by two G protein-coupled pathways.
Pigment cell & melanoma research 2009;22(6):819-26.
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2009: Al-Qassab Hind; Smith Mark A; Irvine Elaine E; Guillermet-Guibert Julie; Claret Marc; Choudhury Agharul I; Selman Colin; Piipari Kaisa; Clements Melanie; Lingard Steven; Chandarana Keval; Bell Jimmy D; Barsh Gregory S; Smith Andrew J H; Batterham Rachel L; Ashford Michael L J; Vanhaesebroeck Bart; Withers Dominic J
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.
Cell metabolism 2009;10(5):343-54.
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2009: Hida Tokimasa; Wakamatsu Kazumasa; Sviderskaya Elena V; Donkin Andrew J; Montoliu Lluis; Lynn Lamoreux M; Yu Bin; Millhauser Glenn L; Ito Shosuke; Barsh Gregory S; Jimbow Kowichi; Bennett Dorothy C
Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway.
Pigment cell & melanoma research 2009;22(5):623-34.
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2009: Pickrell Joseph K; Coop Graham; Novembre John; Kudaravalli Sridhar; Li Jun Z; Absher Devin; Srinivasan Balaji S; Barsh Gregory S; Myers Richard M; Feldman Marcus W; Pritchard Jonathan K
Signals of recent positive selection in a worldwide sample of human populations.
Genome research 2009;19(5):826-37.
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2009: Alizadeh Azita; Hong Lewis Z; Kaelin Christopher B; Raudsepp Terje; Manuel Hermogenes; Barsh Gregory S
Genetics of Sex-linked yellow in the Syrian hamster.
Genetics 2009;181(4):1427-36.
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2009: Anderson Tovi M; vonHoldt Bridgett M; Candille Sophie I; Musiani Marco; Greco Claudia; Stahler Daniel R; Smith Douglas W; Padhukasahasram Badri; Randi Ettore; Leonard Jennifer A; Bustamante Carlos D; Ostrander Elaine A; Tang Hua; Wayne Robert K; Barsh Gregory S
Molecular and evolutionary history of melanism in North American gray wolves.
Science (New York, N.Y.) 2009;323(5919):1339-43.
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2009: Van Raamsdonk Catherine D; Bezrookove Vladimir; Green Gary; Bauer Jürgen; Gaugler Lona; O'Brien Joan M; Simpson Elizabeth M; Barsh Gregory S; Bastian Boris C
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi.
Nature 2009;457(7229):599-602.
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2008: Kaelin C B; Candille S I; Yu B; Jackson P; Thompson D A; Nix M A; Binkley J; Millhauser G L; Barsh G S
New ligands for melanocortin receptors.
International journal of obesity (2005) 2008;32 Suppl 7():S19-27.
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2008: Clément Karine; Dubern Béatrice; Mencarelli Monica; Czernichow Paul; Ito Shosuke; Wakamatsu Kazumasa; Barsh Gregory S; Vaisse Christian; Leger Juliane
Unexpected endocrine features and normal pigmentation in a young adult patient carrying a novel homozygous mutation in the POMC gene.
The Journal of clinical endocrinology and metabolism 2008;93(12):4955-62.
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2008: McGowan Kelly A; Li Jun Z; Park Christopher Y; Beaudry Veronica; Tabor Holly K; Sabnis Amit J; Zhang Weibin; Fuchs Helmut; de Angelis Martin Hrabé; Myers Richard M; Attardi Laura D; Barsh Gregory S
Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects.
Nature genetics 2008;40(8):963-70.
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2008: van de Wall Esther; Leshan Rebecca; Xu Allison W; Balthasar Nina; Coppari Roberto; Liu Shun Mei; Jo Young Hwan; MacKenzie Robert G; Allison David B; Dun Nae J; Elmquist Joel; Lowell Bradford B; Barsh Gregory S; de Luca Carl; Myers Martin G; Schwartz Gary J; Chua Streamson C
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion.
Endocrinology 2008;149(4):1773-85.
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2008: Mesaros Andrea; Koralov Sergei B; Rother Eva; Wunderlich F Thomas; Ernst Marianne B; Barsh Gregory S; Rajewsky Klaus; Brüning Jens C
Activation of Stat3 signaling in AgRP neurons promotes locomotor activity.
Cell metabolism 2008;7(3):236-48.
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2008: Ryu Kwon-Yul; Garza Jacob C; Lu Xin-Yun; Barsh Gregory S; Kopito Ron R
Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):4016-21.
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2008: Alizadeh Azita; Fitch Karen R; Niswender Colleen M; McKnight G Stanley; Barsh Gregory S
Melanocyte-lineage expression of Cre recombinase using Mitf regulatory elements.
Pigment cell & melanoma research 2008;21(1):63-9.
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2008: Li Jun Z; Absher Devin M; Tang Hua; Southwick Audrey M; Casto Amanda M; Ramachandran Sohini; Cann Howard M; Barsh Gregory S; Feldman Marcus; Cavalli-Sforza Luigi L; Myers Richard M
Worldwide human relationships inferred from genome-wide patterns of variation.
Science (New York, N.Y.) 2008;319(5866):1100-4.
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2008: Beliakoff Jason; Lee Jane; Ueno Hiroo; Aiyer Aparna; Weissman Irving L; Barsh Gregory S; Cardiff Robert D; Sun Zijie
The PIAS-like protein Zimp10 is essential for embryonic viability and proper vascular development.
Molecular and cellular biology 2008;28(1):282-92.
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2008: Frankel Wayne N; Barsh Gregory S
PLoS Genetics turns three: looking back, looking ahead.
PLoS genetics 2008;4(7):e1000135.
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2007: Walker Will P; Aradhya Swaroop; Hu Che-Lin; Shen Shiliang; Zhang Wei; Azarani Arezou; Lu XinYun; Barsh Gregory S; Gunn Teresa M
Genetic analysis of attractin homologs.
Genesis (New York, N.Y. : 2000) 2007;45(12):744-56.
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2007: Barsh Gregory S
How the dog got its spots.
Nature genetics 2007;39(11):1304-6.
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2007: Candille Sophie I; Kaelin Christopher B; Cattanach Bruce M; Yu Bin; Thompson Darren A; Nix Matthew A; Kerns Julie A; Schmutz Sheila M; Millhauser Glenn L; Barsh Gregory S
A -defensin mutation causes black coat color in domestic dogs.
Science (New York, N.Y.) 2007;318(5855):1418-23.
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2007: Claret Marc; Smith Mark A; Batterham Rachel L; Selman Colin; Choudhury Agharul I; Fryer Lee G D; Clements Melanie; Al-Qassab Hind; Heffron Helen; Xu Allison W; Speakman John R; Barsh Gregory S; Viollet Benoit; Vaulont Sophie; Ashford Michael L J; Carling David; Withers Dominic J
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.
The Journal of clinical investigation 2007;117(8):2325-36.
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2007: Kerns Julie A; Cargill Edward J; Clark Leigh Anne; Candille Sophie I; Berryere Tom G; Olivier Michael; Lust George; Todhunter Rory J; Schmutz Sheila M; Murphy Keith E; Barsh Gregory S
Linkage and segregation analysis of black and brindle coat color in domestic dogs.
Genetics 2007;176(3):1679-89.
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2007: Könner A Christine; Janoschek Ruth; Plum Leona; Jordan Sabine D; Rother Eva; Ma Xiaosong; Xu Chun; Enriori Pablo; Hampel Brigitte; Barsh Gregory S; Kahn C Ronald; Cowley Michael A; Ashcroft Frances M; Brüning Jens C
Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.
Cell metabolism 2007;5(6):438-49.
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2007: Barsh Gregory; Attardi Laura D
A healthy tan?
The New England journal of medicine 2007;356(21):2208-10.
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2007: Kim Bong Yoon; Olzmann James A; Barsh Gregory S; Chin Lih-Shen; Li Lian
Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking.
Molecular biology of the cell 2007;18(4):1129-42.
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2007: April Craig S; Barsh Gregory S
Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation.
PLoS genetics 2007;3(1):e9.
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2007: Xu Allison W; Ste-Marie Linda; Kaelin Christopher B; Barsh Gregory S
Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding.
Endocrinology 2007;148(1):72-80.
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2007: McGowan Kelly A; Fuchs Helmut; Hrabé de Angelis Martin; Barsh Gregory S
Identification of a Keratin 4 mutation in a chemically induced mouse mutant that models white sponge nevus.
The Journal of investigative dermatology 2007;127(1):60-4.
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2007: Kaelin Christopher B; Cooper Gregory M; Sidow Arend; Barsh Gregory S
Mammalian comparative sequence analysis of the Agrp locus.
PloS one 2007;2(1):e702.
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2006: Jackson Pilgrim J; Douglas Nick R; Chai Biaoxin; Binkley Jonathan; Sidow Arend; Barsh Gregory S; Millhauser Glenn L
Structural and molecular evolutionary analysis of Agouti and Agouti-related proteins.
Chemistry & biology 2006;13(12):1297-305.
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2006: Kaelin Christopher B; Gong Lijie; Xu Allison Wanting; Yao Fayi; Hockman Kristin; Morton Gregory J; Schwartz Michael W; Barsh Gregory S; MacKenzie Robert G
Signal transducer and activator of transcription (stat) binding sites but not stat3 are required for fasting-induced transcription of agouti-related protein messenger ribonucleic acid.
Molecular endocrinology (Baltimore, Md.) 2006;20(10):2591-602.
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2006: Abdul-Rahman Omar A; La Trang H; Kwan Andrea; Schlaubitz Silke; Barsh Greg S; Enns Gregory M; Hudgins Louanne
Genitopatellar syndrome: expanding the phenotype and excluding mutations in LMX1B and TBX4.
American journal of medical genetics. Part A 2006;140(14):1567-72.
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2006: April Craig S; Barsh Gregory S
Skin layer-specific transcriptional profiles in normal and recessive yellow (Mc1re/Mc1re) mice.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2006;19(3):194-205.
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2006: Kitamura Tadahiro; Feng Yun; Kitamura Yukari Ido; Chua Streamson C; Xu Allison W; Barsh Gregory S; Rossetti Luciano; Accili Domenico
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake.
Nature medicine 2006;12(5):534-40.
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2006: McGowan Kelly A; Aradhya Swaroop; Fuchs Helmut; de Angelis Martin H; Barsh Gregory S
A mouse keratin 1 mutation causes dark skin and epidermolytic hyperkeratosis.
The Journal of investigative dermatology 2006;126(5):1013-6.
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2006: Xu Allison W; Barsh Gregory S
MC4R neurons weigh in differently.
Nature neuroscience 2006;9(1):15-6.
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2005: Xu Allison Wanting; Kaelin Christopher B; Morton Gregory J; Ogimoto Kayoko; Stanhope Kimber; Graham James; Baskin Denis G; Havel Peter; Schwartz Michael W; Barsh Gregory S
Effects of hypothalamic neurodegeneration on energy balance.
PLoS biology 2005;3(12):e415.
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2005: Böhm Markus; Eickelmann Mareike; Li Zhuo; Schneider Stefan W; Oji Vinzenz; Diederichs Sven; Barsh Gregory S; Vogt Annika; Stieler Karola; Blume-Peytavi Ulrike; Luger Thomas A
Detection of functionally active melanocortin receptors and evidence for an immunoregulatory activity of alpha-melanocyte-stimulating hormone in human dermal papilla cells.
Endocrinology 2005;146(11):4635-46.
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2005: Gropp Eva; Shanabrough Marya; Borok Erzsebet; Xu Allison W; Janoschek Ruth; Buch Thorsten; Plum Leona; Balthasar Nina; Hampel Brigitte; Waisman Ari; Barsh Gregory S; Horvath Tamas L; Brüning Jens C
Agouti-related peptide-expressing neurons are mandatory for feeding.
Nature neuroscience 2005;8(10):1289-91.
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2005: Cancello Raffaella; Henegar Corneliu; Viguerie Nathalie; Taleb Soraya; Poitou Christine; Rouault Christine; Coupaye Muriel; Pelloux Veronique; Hugol Danielle; Bouillot Jean-Luc; Bouloumié Anne; Barbatelli Giorgio; Cinti Saverio; Svensson Per-Arne; Barsh Gregory S; Zucker Jean-Daniel; Basdevant Arnaud; Langin Dominique; Clément Karine
Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss.
Diabetes 2005;54(8):2277-86.
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2005: Shen Shi-liang; Barsh Gregory S; Wu Zhong-bi
[Attractin]
Zhonghua bing li xue za zhi Chinese journal of pathology 2005;34(7):429-31.
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2005: Berryere Tom G; Kerns Julie A; Barsh Gregory S; Schmutz Sheila M
Association of an Agouti allele with fawn or sable coat color in domestic dogs.
Mammalian genome : official journal of the International Mammalian Genome Society 2005;16(4):262-72.
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2005: Choudhury Agharul I; Heffron Helen; Smith Mark A; Al-Qassab Hind; Xu Allison W; Selman Colin; Simmgen Marcus; Clements Melanie; Claret Marc; Maccoll Gavin; Bedford David C; Hisadome Kazunari; Diakonov Ivan; Moosajee Vazira; Bell Jimmy D; Speakman John R; Batterham Rachel L; Barsh Gregory S; Ashford Michael L J; Withers Dominic J
The role of insulin receptor substrate 2 in hypothalamic and beta cell function.
The Journal of clinical investigation 2005;115(4):940-50.
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2005: Xu Allison Wanting; Kaelin Christopher B; Takeda Kiyoshi; Akira Shizuo; Schwartz Michael W; Barsh Gregory S
PI3K integrates the action of insulin and leptin on hypothalamic neurons.
The Journal of clinical investigation 2005;115(4):951-8.
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2005: Kuijper Sanne; Beverdam Annemiek; Kroon Carla; Brouwer Antje; Candille Sophie; Barsh Gregory; Meijlink Frits
Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes.
Development (Cambridge, England) 2005;132(7):1601-10.
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2005: Poitou C; Viguerie N; Cancello R; De Matteis R; Cinti S; Stich V; Coussieu C; Gauthier E; Courtine M; Zucker J D; Barsh G S; Saris W; Bruneval P; Basdevant A; Langin D; Clément K
Serum amyloid A: production by human white adipocyte and regulation by obesity and nutrition.
Diabetologia 2005;48(3):519-28.
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2005: McNulty Joseph C; Jackson Pilgrim J; Thompson Darren A; Chai Biaoxin; Gantz Ira; Barsh Gregory S; Dawson Philip E; Millhauser Glenn L
Structures of the agouti signaling protein.
Journal of molecular biology 2005;346(4):1059-70.
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2004: Kaelin Christopher B; Xu Allison Wanting; Lu Xin-Yun; Barsh Gregory S
Transcriptional regulation of agouti-related protein (Agrp) in transgenic mice.
Endocrinology 2004;145(12):5798-806.
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2004: Kas Martien J H; Tiesjema Birgitte; van Dijk Gertjan; Garner Keith M; Barsh Gregory S; ter Brake Olivier; Verhaagen Joost; Adan Roger A H
Induction of brain-region-specific forms of obesity by agouti.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(45):10176-81.
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2004: Clément Karine; Viguerie Nathalie; Poitou Christine; Carette Claire; Pelloux Véronique; Curat Cyrile A; Sicard Audrey; Rome Sophie; Benis Arriel; Zucker Jean-Daniel; Vidal Hubert; Laville Martine; Barsh Gregory S; Basdevant Arnaud; Stich Vladimir; Cancello Raffaella; Langin Dominique
Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(14):1657-69.
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2004: Kerns Julie A; Newton J; Berryere Tom G; Rubin Edward M; Cheng Jan-Fang; Schmutz Sheila M; Barsh Gregory S
Characterization of the dog Agouti gene and a nonagoutimutation in German Shepherd Dogs.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(10):798-808.
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2004: Van Raamsdonk Catherine D; Fitch Karen R; Fuchs Helmut; de Angelis Martin Hrabé; Barsh Gregory S
Effects of G-protein mutations on skin color.
Nature genetics 2004;36(9):961-8.
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2004: Viguerie Nathalie; Clement Karine; Barbe Pierre; Courtine Melanie; Benis Arriel; Larrouy Dominique; Hanczar Blaise; Pelloux Veronique; Poitou Christine; Khalfallah Yadh; Barsh Gregory S; Thalamas Claire; Zucker Jean-Daniel; Langin Dominique
In vivo epinephrine-mediated regulation of gene expression in human skeletal muscle.
The Journal of clinical endocrinology and metabolism 2004;89(5):2000-14.
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2004: Candille Sophie I; Van Raamsdonk Catherine D; Chen Changyou; Kuijper Sanne; Chen-Tsai Yanru; Russ Andreas; Meijlink Frits; Barsh Gregory S
Dorsoventral patterning of the mouse coat by Tbx15.
PLoS biology 2004;2(1):E3.
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2003: Barsh Gregory S
What controls variation in human skin color?
PLoS biology 2003;1(1):E27.
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2003: McIntire Jennifer J; Umetsu Sarah E; Macaubas Claudia; Hoyte Elizabeth G; Cinnioglu Cengiz; Cavalli-Sforza Luigi L; Barsh Gregory S; Hallmayer Joachim F; Underhill Peter A; Risch Neil J; Freeman Gordon J; DeKruyff Rosemarie H; Umetsu Dale T
Immunology: hepatitis A virus link to atopic disease.
Nature 2003;425(6958):576.
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2003: Lu Xin-Yun; Barsh Gregory S; Akil Huda; Watson Stanley J
Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(21):7863-72.
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2003: He Lin; Eldridge Adam G; Jackson Peter K; Gunn Teresa M; Barsh Gregory S
Accessory proteins for melanocortin signaling: attractin and mahogunin.
Annals of the New York Academy of Sciences 2003;994():288-98.
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2003: Millhauser Glenn L; McNulty Joe C; Jackson Pilgrim J; Thompson Darren A; Barsh Gregory S; Gantz Ira
Loops and links: structural insights into the remarkable function of the agouti-related protein.
Annals of the New York Academy of Sciences 2003;994():27-35.
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2003: Rome Sophie; Clément Karine; Rabasa-Lhoret Rémi; Loizon Emmanuelle; Poitou Christine; Barsh Greg S; Riou Jean-Paul; Laville Martine; Vidal Hubert
Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp.
The Journal of biological chemistry 2003;278(20):18063-8.
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2003: Chai Biao-Xin; Neubig Richard R; Millhauser Glenn L; Thompson Darren A; Jackson Pilgrim J; Barsh Gregory S; Dickinson Chris J; Li Ji-Yao; Lai Yu-Mei; Gantz Ira
Inverse agonist activity of agouti and agouti-related protein.
Peptides 2003;24(4):603-9.
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2003: Schwartz Michael W; Woods Stephen C; Seeley Randy J; Barsh Gregory S; Baskin Denis G; Leibel Rudolph L
Is the energy homeostasis system inherently biased toward weight gain?
Diabetes 2003;52(2):232-8.
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2003: Kerns J A; Olivier M; Lust G; Barsh G S
Exclusion of melanocortin-1 receptor (mc1r) and agouti as candidates for dominant black in dogs.
The Journal of heredity 2003;94(1):75-9.
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2003: Schmutz S M; Berryere T G; Ellinwood N M; Kerns J A; Barsh G S
MC1R studies in dogs with melanistic mask or brindle patterns.
The Journal of heredity 2003;94(1):69-73.
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2003: He Lin; Lu Xin-Yun; Jolly Aaron F; Eldridge Adam G; Watson Stanley J; Jackson Peter K; Barsh Gregory S; Gunn Teresa M
Spongiform degeneration in mahoganoid mutant mice.
Science (New York, N.Y.) 2003;299(5607):710-2.
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2003: Fitch Karen R; McGowan Kelly A; van Raamsdonk Catherine D; Fuchs Helmut; Lee Daekee; Puech Anne; Hérault Yann; Threadgill David W; Hrabé de Angelis Martin; Barsh Gregory S
Genetics of dark skin in mice.
Genes & development 2003;17(2):214-28.
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2002: Lu Xin-Yun; Shieh Kun-Ruey; Kabbaj Mohamed; Barsh Gregory S; Akil Huda; Watson Stanley J
Diurnal rhythm of agouti-related protein and its relation to corticosterone and food intake.
Endocrinology 2002;143(10):3905-15.
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2002: Barsh Gregory S; Schwartz Michael W
Genetic approaches to studying energy balance: perception and integration.
Nature reviews. Genetics 2002;3(8):589-600.
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2002: Jackson Pilgrim J; McNulty Joseph C; Yang Ying-Kui; Thompson Darren A; Chai Biaoxin; Gantz Ira; Barsh Gregory S; Millhauser Glenn L
Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity.
Biochemistry 2002;41(24):7565-72.
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2002: Barsh Gregory S; He Lin; Gunn Teresa M
Genetic and biochemical studies of the Agouti-attractin system.
Journal of receptor and signal transduction research 2002;22(1-4):63-77.
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2002: Clément Karine; Viguerie Nathalie; Diehn Maximilian; Alizadeh Ash; Barbe Pierre; Thalamas Claire; Storey John D; Brown Patrick O; Barsh Greg S; Langin Dominique
In vivo regulation of human skeletal muscle gene expression by thyroid hormone.
Genome research 2002;12(2):281-91.
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2002: Gunn Teresa M; Azarani Arezou; Kim Philip H; Hyman Richard W; Davis Ronald W; Barsh Gregory S
Identification and preliminary characterization of mouse Adam33.
BMC genetics 2002;3():2.
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2001: McNulty J C; Thompson D A; Bolin K A; Wilken J; Barsh G S; Millhauser G L
High-resolution NMR structure of the chemically-synthesized melanocortin receptor binding domain AGRP(87-132) of the agouti-related protein.
Biochemistry 2001;40(51):15520-7.
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2001: McIntire J J; Umetsu S E; Akbari O; Potter M; Kuchroo V K; Barsh G S; Freeman G J; Umetsu D T; DeKruyff R H
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family.
Nature immunology 2001;2(12):1109-16.
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2001: Gunn T M; Inui T; Kitada K; Ito S; Wakamatsu K; He L; Bouley D M; Serikawa T; Barsh G S
Molecular and phenotypic analysis of Attractin mutant mice.
Genetics 2001;158(4):1683-95.
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2001: Abdel-Malek Z A; Scott M C; Furumura M; Lamoreux M L; Ollmann M; Barsh G S; Hearing V J
The melanocortin 1 receptor is the principal mediator of the effects of agouti signaling protein on mammalian melanocytes.
Journal of cell science 2001;114(Pt 5):1019-24.
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2001: He L; Gunn T M; Bouley D M; Lu X Y; Watson S J; Schlossman S F; Duke-Cohan J S; Barsh G S
A biochemical function for attractin in agouti-induced pigmentation and obesity.
Nature genetics 2001;27(1):40-7.
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2001: Oosterom J; Garner K M; den Dekker WK; Nijenhuis W A; Gispen W H; Burbach J P; Barsh G S; Adan R A
Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, Agouti protein.
The Journal of biological chemistry 2001;276(2):931-6.
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2000: Barsh G; Gunn T; He L; Wilson B; Lu X; Gantz I; Watson S
Neuroendocrine regulation by the Agouti/Agrp-melanocortin system.
Endocrine research 2000;26(4):571.
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2000: Li J Y; Finniss S; Yang Y K; Zeng Q; Qu S Y; Barsh G; Dickinson C; Gantz I
Agouti-related protein-like immunoreactivity: characterization of release from hypothalamic tissue and presence in serum.
Endocrinology 2000;141(6):1942-50.
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2000: Tang W; Gunn T M; McLaughlin D F; Barsh G S; Schlossman S F; Duke-Cohan J S
Secreted and membrane attractin result from alternative splicing of the human ATRN gene.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6025-30.
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2000: Barsh G S; Farooqi I S; O'Rahilly S
Genetics of body-weight regulation.
Nature 2000;404(6778):644-51.
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2000: Gunn T M; Barsh G S
Mahogany/attractin: en route from phenotype to function.
Trends in cardiovascular medicine 2000;10(2):76-81.
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2000: Ring B Z; Cordes S P; Overbeek P A; Barsh G S
Regulation of mouse lens fiber cell development and differentiation by the Maf gene.
Development (Cambridge, England) 2000;127(2):307-17.
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2000: Newton J M; Wilkie A L; He L; Jordan S A; Metallinos D L; Holmes N G; Jackson I J; Barsh G S
Melanocortin 1 receptor variation in the domestic dog.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(1):24-30.
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2000: Abdel-Malek Z; Scott M C; Suzuki I; Tada A; Im S; Lamoreux L; Ito S; Barsh G; Hearing V J
The melanocortin-1 receptor is a key regulator of human cutaneous pigmentation.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2000;13 Suppl 8():156-62.
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2000: Barsh G; Gunn T; He L; Schlossman S; Duke-Cohan J
Biochemical and genetic studies of pigment-type switching.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2000;13 Suppl 8():48-53.
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1999: Marsh D J; Miura G I; Yagaloff K A; Schwartz M W; Barsh G S; Palmiter R D
Effects of neuropeptide Y deficiency on hypothalamic agouti-related protein expression and responsiveness to melanocortin analogues.
Brain research 1999;848(1-2):66-77.
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1999: Barsh G S; Ollmann M M; Wilson B D; Miller K A; Gunn T M
Molecular pharmacology of Agouti protein in vitro and in vivo.
Annals of the New York Academy of Sciences 1999;885():143-52.
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1999: Suzuki I; Im S; Tada A; Scott C; Akcali C; Davis M B; Barsh G; Hearing V; Abdel-Malek Z
Participation of the melanocortin-1 receptor in the UV control of pigmentation.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1999;4(1):29-34.
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1999: Bagnol D; Lu X Y; Kaelin C B; Day H E; Ollmann M; Gantz I; Akil H; Barsh G S; Watson S J
Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(18):RC26.
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1999: Wilson B D; Ollmann M M; Barsh G S
The role of agouti-related protein in regulating body weight.
Molecular medicine today 1999;5(6):250-6.
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1999: Ollmann M M; Barsh G S
Down-regulation of melanocortin receptor signaling mediated by the amino terminus of Agouti protein in Xenopus melanophores.
The Journal of biological chemistry 1999;274(22):15837-46.
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1999: Wilson B D; Bagnol D; Kaelin C B; Ollmann M M; Gantz I; Watson S J; Barsh G S
Physiological and anatomical circuitry between Agouti-related protein and leptin signaling.
Endocrinology 1999;140(5):2387-97.
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1999: Gunn T M; Miller K A; He L; Hyman R W; Davis R W; Azarani A; Schlossman S F; Duke-Cohan J S; Barsh G S
The mouse mahogany locus encodes a transmembrane form of human attractin.
Nature 1999;398(6723):152-6.
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1999: Millar S E; Willert K; Salinas P C; Roelink H; Nusse R; Sussman D J; Barsh G S
WNT signaling in the control of hair growth and structure.
Developmental biology 1999;207(1):133-49.
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1999: Wang J; Wilhelmsson H; Graff C; Li H; Oldfors A; Rustin P; Brüning J C; Kahn C R; Clayton D A; Barsh G S; Thorén P; Larsson N G
Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.
Nature genetics 1999;21(1):133-7.
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1999: Yang Y K; Thompson D A; Dickinson C J; Wilken J; Barsh G S; Kent S B; Gantz I
Characterization of Agouti-related protein binding to melanocortin receptors.
Molecular endocrinology (Baltimore, Md.) 1999;13(1):148-55.
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1998: Elias C F; Saper C B; Maratos-Flier E; Tritos N A; Lee C; Kelly J; Tatro J B; Hoffman G E; Ollmann M M; Barsh G S; Sakurai T; Yanagisawa M; Elmquist J K
Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area.
The Journal of comparative neurology 1998;402(4):442-59.
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1998: Furumura M; Sakai C; Potterf S B; Vieira W D; Barsh G S; Hearing V J
Characterization of genes modulated during pheomelanogenesis using differential display.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7374-8.
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1998: Larsson N G; Wang J; Wilhelmsson H; Oldfors A; Rustin P; Lewandoski M; Barsh G S; Clayton D A
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice.
Nature genetics 1998;18(3):231-6.
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1998: Ollmann M M; Lamoreux M L; Wilson B D; Barsh G S
Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo.
Genes & development 1998;12(3):316-30.
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1997: Ollmann M M; Wilson B D; Yang Y K; Kerns J A; Chen Y; Gantz I; Barsh G S
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein.
Science (New York, N.Y.) 1997;278(5335):135-8.
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1997: Miller K A; Gunn T M; Carrasquillo M M; Lamoreux M L; Galbraith D B; Barsh G S
Genetic studies of the mouse mutations mahogany and mahoganoid.
Genetics 1997;146(4):1407-15.
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1997: Sakai C; Ollmann M; Kobayashi T; Abdel-Malek Z; Muller J; Vieira W D; Imokawa G; Barsh G S; Hearing V J
Modulation of murine melanocyte function in vitro by agouti signal protein.
The EMBO journal 1997;16(12):3544-52.
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1997: Suzuki I; Tada A; Ollmann M M; Barsh G S; Im S; Lamoreux M L; Hearing V J; Nordlund J J; Abdel-Malek Z A
Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to alpha-melanotropin.
The Journal of investigative dermatology 1997;108(6):838-42.
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1997: Hein L; Stevens M E; Barsh G S; Pratt R E; Kobilka B K; Dzau V J
Overexpression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6391-6.
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1997: Yang Y K; Ollmann M M; Wilson B D; Dickinson C; Yamada T; Barsh G S; Gantz I
Effects of recombinant agouti-signaling protein on melanocortin action.
Molecular endocrinology (Baltimore, Md.) 1997;11(3):274-80.
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1997: Desai K H; Sato R; Schauble E; Barsh G S; Kobilka B K; Bernstein D
Cardiovascular indexes in the mouse at rest and with exercise: new tools to study models of cardiac disease.
The American journal of physiology 1997;272(2 Pt 2):H1053-61.
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1997: Larsson N G; Oldfors A; Garman J D; Barsh G S; Clayton D A
Down-regulation of mitochondrial transcription factor A during spermatogenesis in humans.
Human molecular genetics 1997;6(2):185-91.
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1997: Larsson N G; Barsh G S; Clayton D A
Structure and chromosomal localization of the mouse mitochondrial transcription factor A gene (Tfam).
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(2):139-40.
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1996: Newton J M; Orlow S J; Barsh G S
Isolation and characterization of a mouse homolog of the X-linked ocular albinism (OA1) gene.
Genomics 1996;37(2):219-25.
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1996: Chen Y; Duhl D M; Barsh G S
Opposite orientations of an inverted duplication and allelic variation at the mouse agouti locus.
Genetics 1996;144(1):265-77.
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1996: Furumura M; Sakai C; Abdel-Malek Z; Barsh G S; Hearing V J
The interaction of agouti signal protein and melanocyte stimulating hormone to regulate melanin formation in mammals.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1996;9(4):191-203.
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1996: Barsh G S
The genetics of pigmentation: from fancy genes to complex traits.
Trends in genetics : TIG 1996;12(8):299-305.
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1996: Link R E; Desai K; Hein L; Stevens M E; Chruscinski A; Bernstein D; Barsh G S; Kobilka B K
Cardiovascular regulation in mice lacking alpha2-adrenergic receptor subtypes b and c.
Science (New York, N.Y.) 1996;273(5276):803-5.
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1996: Rohrer D K; Desai K H; Jasper J R; Stevens M E; Regula D P; Barsh G S; Bernstein D; Kobilka B K
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7375-80.
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1996: Larsson N G; Garman J D; Oldfors A; Barsh G S; Clayton D A
A single mouse gene encodes the mitochondrial transcription factor A and a testis-specific nuclear HMG-box protein.
Nature genetics 1996;13(3):296-302.
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1995: Hein L; Dzau V J; Barsh G S
Linkage mapping of the angiotensin AT2 receptor gene (Agtr2) to the mouse X chromosome.
Genomics 1995;30(2):369-71.
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1995: Millar S E; Miller M W; Stevens M E; Barsh G S
Expression and transgenic studies of the mouse agouti gene provide insight into the mechanisms by which mammalian coat color patterns are generated.
Development (Cambridge, England) 1995;121(10):3223-32.
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1995: Hein L; Barsh G S; Pratt R E; Dzau V J; Kobilka B K
Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice.
Nature 1995;377(6551):744-7.
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1995: Link R E; Stevens M S; Kulatunga M; Scheinin M; Barsh G S; Kobilka B K
Targeted inactivation of the gene encoding the mouse alpha 2c-adrenoceptor homolog.
Molecular pharmacology 1995;48(1):48-55.
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1995: Wilson B D; Ollmann M M; Kang L; Stoffel M; Bell G I; Barsh G S
Structure and function of ASP, the human homolog of the mouse agouti gene.
Human molecular genetics 1995;4(2):223-30.
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1994: Cordes S P; Barsh G S
The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor.
Cell 1994;79(6):1025-34.
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1994: Duhl D M; Vrieling H; Miller K A; Wolff G L; Barsh G S
Neomorphic agouti mutations in obese yellow mice.
Nature genetics 1994;8(1):59-65.
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1994: Vrieling H; Duhl D M; Millar S E; Miller K A; Barsh G S
Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5667-71.
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1994: Duhl D M; Stevens M E; Vrieling H; Saxon P J; Miller M W; Epstein C J; Barsh G S
Pleiotropic effects of the mouse lethal yellow (Ay) mutation explained by deletion of a maternally expressed gene and the simultaneous production of agouti fusion RNAs.
Development (Cambridge, England) 1994;120(6):1695-708.
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1994: Miller M W; Duhl D M; Winkes B M; Arredondo-Vega F; Saxon P J; Wolff G L; Epstein C J; Hershfield M S; Barsh G S
The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene.
The EMBO journal 1994;13(8):1806-16.
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1994: Winkes B M; Ollmann M M; Barsh G S
Association of Xmv-10 and the non-agouti (a) mutation explained by close linkage instead of causality.
Mammalian genome : official journal of the International Mammalian Genome Society 1994;5(1):3-10.
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1993: Link R E; Kobilka B K; Barsh G S
Linkage mapping of alpha-2 adrenergic receptor genes to mouse chromosomes 2 and 5.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(11):650-5.
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1993: Dedera D A; Waller E K; LeBrun D P; Sen-Majumdar A; Stevens M E; Barsh G S; Cleary M L
Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice.
Cell 1993;74(5):833-43.
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1993: Miller M W; Duhl D M; Vrieling H; Cordes S P; Ollmann M M; Winkes B M; Barsh G S
Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation.
Genes & development 1993;7(3):454-67.
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1993: Frohman M A; Martin G R; Cordes S P; Halamek L P; Barsh G S
Altered rhombomere-specific gene expression and hyoid bone differentiation in the mouse segmentation mutant, kreisler (kr).
Development (Cambridge, England) 1993;117(3):925-36.
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1993: von Zastrow M; Link R; Daunt D; Barsh G; Kobilka B
Subtype-specific differences in the intracellular sorting of G protein-coupled receptors.
The Journal of biological chemistry 1993;268(2):763-6.
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1992: Andria M L; Barsh G S; Levy S
Expression of TAPA-1 in preimplantation mouse embryos.
Biochemical and biophysical research communications 1992;186(3):1201-6.
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1992: Chruscinski A J; Link R E; Daunt D A; Barsh G S; Kobilka B K
Cloning and expression of the mouse homolog of the human alpha 2-C2 adrenergic receptor.
Biochemical and biophysical research communications 1992;186(3):1280-7.
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1992: Ollmann M M; Winkes B M; Barsh G S
Construction, analysis, and application of a radiation hybrid mapping panel surrounding the mouse agouti locus.
Genomics 1992;13(3):731-40.
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1992: Link R; Daunt D; Barsh G; Chruscinski A; Kobilka B
Cloning of two mouse genes encoding alpha 2-adrenergic receptor subtypes and identification of a single amino acid in the mouse alpha 2-C10 homolog responsible for an interspecies variation in antagonist binding.
Molecular pharmacology 1992;42(1):16-27.
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1990: Barsh G S; Lovett M; Epstein C J
Effects of the lethal yellow (Ay) mutation in mouse aggregation chimeras.
Development (Cambridge, England) 1990;109(3):683-90.
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1989: Barsh G S; Epstein C J
The long-range restriction map surrounding the mouse agouti locus reveals a disparity between physical and genetic distances.
Genomics 1989;5(1):9-18.
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1989: Barsh G S; Epstein C J
Physical and genetic characterization of a 75-kilobase deletion associated with al, a recessive lethal allele at the mouse agouti locus.
Genetics 1989;121(4):811-8.
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