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Aldons Lusis

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Orozco Luz D; Cokus Shawn J; Ghazalpour Anatole; Ingram-Drake Leslie; Wang Susanna; van Nas Atila; Che Nam; Araujo Jesus A; Pellegrini Matteo; Lusis Aldons J
Copy number variation influences gene expression and metabolic traits in mice.
Shih Diana M; Lusis Aldons J
The roles of PON1 and PON2 in cardiovascular disease and innate immunity.
Gale G D; Yazdi R D; Khan A H; Lusis A J; Davis R C; Smith D J
A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci.

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All Publications

2009: Orozco Luz D; Cokus Shawn J; Ghazalpour Anatole; Ingram-Drake Leslie; Wang Susanna; van Nas Atila; Che Nam; Araujo Jesus A; Pellegrini Matteo; Lusis Aldons J
Copy number variation influences gene expression and metabolic traits in mice.
Human molecular genetics 2009;18(21):4118-29.
2009: Shih Diana M; Lusis Aldons J
The roles of PON1 and PON2 in cardiovascular disease and innate immunity.
Current opinion in lipidology 2009;20(4):288-92.
2009: Gale G D; Yazdi R D; Khan A H; Lusis A J; Davis R C; Smith D J
A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci.
Molecular psychiatry 2009;14(6):631-45.
2009: Farber Charles R; Aten Jason E; Farber Emily A; de Vera Vincent; Gularte Rodrigo; Islas-Trejo Alma; Wen Pengzi; Horvath Steve; Lucero Michael; Lusis Aldons J; Medrano Juan F
Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling.
Physiological genomics 2009;37(3):294-302.
2009: White Cory H; Ohmen Jeffrey D; Sheth Sonal; Zebboudj Amina F; McHugh Richard K; Hoffman Larry F; Lusis Aldons J; Davis Richard C; Friedman Rick A
Genome-wide screening for genetic loci associated with noise-induced hearing loss.
Mammalian genome : official journal of the International Mammalian Genome Society 2009;20(4):207-13.
2009: Wu Sulin; Lusis Aldons J; Drake Thomas A
A systems-based framework for understanding complex metabolic and cardiovascular disorders.
Journal of lipid research 2009;50 Suppl():S358-63.
2009: Shaposhnik Zory; Wang Xuping; Trias Joaquim; Fraser Heather; Lusis Aldons J
The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002).
Journal of lipid research 2009;50(4):623-9.
2009: Bennett Brian J; Wang Susanna S; Wang Xuping; Wu Xiaohui; Lusis Aldons J
Genetic regulation of atherosclerotic plaque size and morphology in the innominate artery of hyperlipidemic mice.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(3):348-55.
2009: Bhasin Kum Kum S; van Nas Atila; Martin Lisa J; Davis Richard C; Devaskar Sherin U; Lusis Aldons J
Maternal low-protein diet or hypercholesterolemia reduces circulating essential amino acids and leads to intrauterine growth restriction.
Diabetes 2009;58(3):559-66.
2009: van Nas Atila; Guhathakurta Debraj; Wang Susanna S; Yehya Nadir; Horvath Steve; Zhang Bin; Ingram-Drake Leslie; Chaudhuri Gautam; Schadt Eric E; Drake Thomas A; Arnold Arthur P; Lusis Aldons J
Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks.
Endocrinology 2009;150(3):1235-49.
2009: Mungrue Imran N; Pagnon Joanne; Kohannim Omid; Gargalovic Peter S; Lusis Aldons J
CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascade.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(1):466-76.
2008: Lusis Aldons J; Attie Alan D; Reue Karen
Metabolic syndrome: from epidemiology to systems biology.
Nature reviews. Genetics 2008;9(11):819-30.
2008: Allayee Hooman; Baylin Ana; Hartiala Jaana; Wijesuriya Hemani; Mehrabian Margarete; Lusis Aldons J; Campos Hannia
Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction.
The American journal of clinical nutrition 2008;88(4):934-40.
2008: Chen Junqin; Hui Simon T; Couto Francesca M; Mungrue Imran N; Davis Dawn B; Attie Alan D; Lusis Aldons J; Davis Roger A; Shalev Anath
Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(10):3581-94.
2008: Oskolkova Olga V; Afonyushkin Taras; Leitner Alexander; von Schlieffen Elena; Gargalovic Peter S; Lusis Aldons J; Binder Bernd R; Bochkov Valery N
ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response.
Blood 2008;112(2):330-9.
2008: Mehrabian M; Schulthess F T; Nebohacova M; Castellani L W; Zhou Z; Hartiala J; Oberholzer J; Lusis A J; Maedler K; Allayee H
Identification of ALOX5 as a gene regulating adiposity and pancreatic function.
Diabetologia 2008;51(6):978-88.
2008: Mar-Heyming Rebecca; Miyazaki Makoto; Weissglas-Volkov Daphna; Kolaitis Nicholas A; Sadaat Narimaan; Plaisier Christopher; Pajukanta Päivi; Cantor Rita M; de Bruin Tjerk W A; Ntambi James M; Lusis Aldons J
Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(6):1193-9.
2008: Park Christopher C; Ahn Sangtae; Bloom Joshua S; Lin Andy; Wang Richard T; Wu Tongtong; Sekar Aswin; Khan Arshad H; Farr Christine J; Lusis Aldons J; Leahy Richard M; Lange Kenneth; Smith Desmond J
Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids.
Nature genetics 2008;40(4):421-9.
2008: Chen Junqin; Saxena Geetu; Mungrue Imran N; Lusis Aldons J; Shalev Anath
Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.
Diabetes 2008;57(4):938-44.
2008: Castellani Lawrence W; Nguyen Cara N; Charugundla Sarada; Weinstein Michael M; Doan Chau X; Blaner William S; Wongsiriroj Nuttaporn; Lusis Aldons J
Apolipoprotein AII is a regulator of very low density lipoprotein metabolism and insulin resistance.
The Journal of biological chemistry 2008;283(17):11633-44.
2008: Bhattacharyya Tamali; Nicholls Stephen J; Topol Eric J; Zhang Renliang; Yang Xia; Schmitt David; Fu Xiaoming; Shao Mingyuan; Brennan Danielle M; Ellis Stephen G; Brennan Marie-Luise; Allayee Hooman; Lusis Aldons J; Hazen Stanley L
Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk.
JAMA : the journal of the American Medical Association 2008;299(11):1265-76.
2008: Chen Yanqing; Zhu Jun; Lum Pek Yee; Yang Xia; Pinto Shirly; MacNeil Douglas J; Zhang Chunsheng; Lamb John; Edwards Stephen; Sieberts Solveig K; Leonardson Amy; Castellini Lawrence W; Wang Susanna; Champy Marie-France; Zhang Bin; Emilsson Valur; Doss Sudheer; Ghazalpour Anatole; Horvath Steve; Drake Thomas A; Lusis Aldons J; Schadt Eric E
Variations in DNA elucidate molecular networks that cause disease.
Nature 2008;452(7186):429-35.
2008: Araujo Jesus A; Barajas Berenice; Kleinman Michael; Wang Xuping; Bennett Brian J; Gong Ke Wei; Navab Mohamad; Harkema Jack; Sioutas Constantinos; Lusis Aldons J; Nel Andre E
Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress.
Circulation research 2008;102(5):589-96.
2008: McLin Jessica Pilar; Thompson Leslie Michels; Lusis Aldons J; Davis Richard C; Steward Oswald
Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid.
Neurobiology of disease 2008;29(3):391-9.
2008: Lusis Aldons J; Pajukanta Päivi
A treasure trove for lipoprotein biology.
Nature genetics 2008;40(2):129-30.
2008: Ghazalpour Anatole; Doss Sudheer; Kang Hyun; Farber Charles; Wen Ping-Zi; Brozell Alec; Castellanos Ruth; Eskin Eleazar; Smith Desmond J; Drake Thomas A; Lusis Aldons J
High-resolution mapping of gene expression using association in an outbred mouse stock.
PLoS genetics 2008;4(8):e1000149.
2008: Aten Jason E; Fuller Tova F; Lusis Aldons J; Horvath Steve
Using genetic markers to orient the edges in quantitative trait networks: the NEO software.
BMC systems biology 2008;2():34.
2008: Farber Charles R; Lusis Aldons J
Integrating global gene expression analysis and genetics.
Advances in genetics 2008;60():571-601.
2007: Wang Susanna S; Shi Weibin; Wang Xuping; Velky Leandra; Greenlee Sarah; Wang Min T; Drake Thomas A; Lusis Aldons J
Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):2671-6.
2007: Péterfy Miklós; Davis Richard C; Lusis Aldons J
Metabolic syndrome as a modifier of atherosclerosis in murine models.
Current drug targets 2007;8(11):1215-20.
2007: Bennett Brian J; Romanoski Casey E; Lusis Aldons J
Network-centered view of coronary artery disease.
Expert review of cardiovascular therapy 2007;5(6):1095-103.
2007: Lusis Aldons J; Yu Janet; Wang Susanna S
The problem of passenger genes in transgenic mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(10):2100-3.
2007: Lee Jenny C; Weissglas-Volkov Daphna; Kyttälä Mira; Sinsheimer Janet S; Jokiaho Anne; de Bruin Tjerk W A; Lusis Aldons J; Brennan Marie-Luise; van Greevenbroek Marleen M J; van der Kallen Carla J H; Hazen Stanley L; Pajukanta Päivi
USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(10):2222-7.
2007: Moen Corina J A; Tholens Aart P; Voshol Peter J; de Haan Willeke; Havekes Louis M; Gargalovic Peter; Lusis Aldons J; van Dyk Ko Willems; Frants Rune R; Hofker Marten H; Rensen Patrick C N
The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglycerides.
Journal of lipid research 2007;48(10):2182-92.
2007: Davis Richard C; Jin Angela; Rosales Melenie; Yu Suzanne; Xia Xiaoyu; Ranola Kathleen; Schadt Eric E; Lusis Aldons J
A genome-wide set of congenic mouse strains derived from CAST/Ei on a C57BL/6 background.
Genomics 2007;90(3):306-13.
2007: Bradley Michelle N; Hong Cynthia; Chen Mingyi; Joseph Sean B; Wilpitz Damien C; Wang Xuping; Lusis Aldons J; Collins Allan; Hseuh Willa A; Collins Jon L; Tangirala Rajendra K; Tontonoz Peter
Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE.
The Journal of clinical investigation 2007;117(8):2337-46.
2007: Wang Susanna S; Schadt Eric E; Wang Hui; Wang Xuping; Ingram-Drake Leslie; Shi Weibin; Drake Thomas A; Lusis Aldons J
Identification of pathways for atherosclerosis in mice: integration of quantitative trait locus analysis and global gene expression data.
Circulation research 2007;101(3):e11-30.
2007: Fuller Tova F; Ghazalpour Anatole; Aten Jason E; Drake Thomas A; Lusis Aldons J; Horvath Steve
Weighted gene coexpression network analysis strategies applied to mouse weight.
Mammalian genome : official journal of the International Mammalian Genome Society 2007;18(6-7):463-72.
2007: Orozco Luz D; Kapturczak Matthias H; Barajas Berenice; Wang Xuping; Weinstein Michael M; Wong Jack; Deshane Jessy; Bolisetty Subhashini; Shaposhnik Zory; Shih Diana M; Agarwal Anupam; Lusis Aldons J; Araujo Jesus A
Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis.
Circulation research 2007;100(12):1703-11.
2007: Gharavi Nima M; Gargalovic Peter S; Chang Irene; Araujo Jesus A; Clark Michael J; Szeto Wan Lam; Watson Andrew D; Lusis Aldons J; Berliner Judith A
High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(6):1346-53.
2007: Shih Diana M; Xia Yu-Rong; Wang Xu-Ping; Wang Susanna S; Bourquard Noam; Fogelman Alan M; Lusis Aldons J; Reddy Srinivasa T
Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice.
Circulation research 2007;100(8):1200-7.
2007: Feng Xuebing; Li Hongyun; Rumbin Alexis A; Wang Xuping; La Cava Antonio; Brechtelsbauer Katherine; Castellani Lawrence W; Witztum Joseph L; Lusis Aldons J; Tsao Betty P
ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia.
Journal of lipid research 2007;48(4):794-805.
2007: Stoltz David A; Ozer Egon A; Ng Carey J; Yu Janet M; Reddy Srinivasa T; Lusis Aldons J; Bourquard Noam; Parsek Matthew R; Zabner Joseph; Shih Diana M
Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia.
American journal of physiology. Lung cellular and molecular physiology 2007;292(4):L852-60.
2007: Meng Haijin; Vera Iset; Che Nam; Wang Xuping; Wang Susanna S; Ingram-Drake Leslie; Schadt Eric E; Drake Thomas A; Lusis Aldons J
Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4530-5.
2007: Shaposhnik Zory; Wang Xuping; Weinstein Michael; Bennett Brian J; Lusis Aldons J
Granulocyte macrophage colony-stimulating factor regulates dendritic cell content of atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(3):621-7.
2007: Gong Ke Wei; Zhao Wei; Li Ning; Barajas Berenice; Kleinman Michael; Sioutas Constantinos; Horvath Steve; Lusis Aldons J; Nel Andre; Araujo Jesus A
Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells.
Genome biology 2007;8(7):R149.
2007: Itoh Yuichiro; Melamed Esther; Yang Xia; Kampf Kathy; Wang Susanna; Yehya Nadir; Van Nas Atila; Replogle Kirstin; Band Mark R; Clayton David F; Schadt Eric E; Lusis Aldons J; Arnold Arthur P
Dosage compensation is less effective in birds than in mammals.
Journal of biology 2007;6(1):2.
2006: Parks Brian W; Lusis Aldons J; Kabarowski Janusz H S
Loss of the lysophosphatidylcholine effector, G2A, ameliorates aortic atherosclerosis in low-density lipoprotein receptor knockout mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2703-9.
2006: Brouwers Martijn C G J; Cantor Rita M; Kono Naoko; Yoon Jeong Lim; van der Kallen Carla J H; Bilderbeek-Beckers Monique A L; van Greevenbroek Marleen M J; Lusis Aldons J; de Bruin Tjerk W A
Heritability and genetic loci of fatty liver in familial combined hyperlipidemia.
Journal of lipid research 2006;47(12):2799-807.
2006: Gargalovic Peter S; Gharavi Nima M; Clark Michael J; Pagnon Joanne; Yang Wen-Pin; He Aiqing; Truong Amy; Baruch-Oren Tamar; Berliner Judith A; Kirchgessner Todd G; Lusis Aldons J
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(11):2490-6.
2006: Bhasin Kum Kum; Yu Janet M; Tward Aaron; Shih Diana; Campbell David A; Lusis Aldons J
Trypanosoma congolense: paraoxonase 1 prolongs survival of infected mice.
Experimental parasitology 2006;114(3):240-5.
2006: Ng Carey J; Bourquard Noam; Grijalva Victor; Hama Susan; Shih Diana M; Navab Mohamad; Fogelman Alan M; Lusis Aldons J; Young Stephen; Reddy Srinivasa T
Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2.
The Journal of biological chemistry 2006;281(40):29491-500.
2006: Zhang Yanqiao; Wang Xuping; Vales Charisse; Lee Florence Ying; Lee Hans; Lusis Aldons J; Edwards Peter A
FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2316-21.
2006: Lusis Aldons J
A thematic review series: systems biology approaches to metabolic and cardiovascular disorders.
Journal of lipid research 2006;47(9):1887-90.
2006: Ghazalpour Anatole; Doss Sudheer; Zhang Bin; Wang Susanna; Plaisier Christopher; Castellanos Ruth; Brozell Alec; Schadt Eric E; Drake Thomas A; Lusis Aldons J; Horvath Steve
Integrating genetic and network analysis to characterize genes related to mouse weight.
PLoS genetics 2006;2(8):e130.
2006: Gargalovic Peter S; Imura Minori; Zhang Bin; Gharavi Nima M; Clark Michael J; Pagnon Joanne; Yang Wen-Pin; He Aiqing; Truong Amy; Patel Shilpa; Nelson Stanley F; Horvath Steve; Berliner Judith A; Kirchgessner Todd G; Lusis Aldons J
Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(34):12741-6.
2006: Estrada-Smith Daria; Collins Alan R; Wang Xuping; Crockett Craig; Castellani Lawrence; Lusis Aldons J; Davis Richard C
Impact of chromosome 2 obesity loci on cardiovascular complications of insulin resistance in LDL receptor-deficient C57BL/6 mice.
Diabetes 2006;55(8):2265-71.
2006: Yang Xia; Schadt Eric E; Wang Susanna; Wang Hui; Arnold Arthur P; Ingram-Drake Leslie; Drake Thomas A; Lusis Aldons J
Tissue-specific expression and regulation of sexually dimorphic genes in mice.
Genome research 2006;16(8):995-1004.
2006: Castellani Lawrence W; Chang James J; Wang Xuping; Lusis Aldons J; Reynolds Wanda F
Transgenic mice express human MPO -463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in -463G males.
Journal of lipid research 2006;47(7):1366-77.
2006: Miyoshi Toru; Li Yuhua; Shih Diana M; Wang Xuping; Laubach Victor E; Matsumoto Alan H; Helm Gregory A; Lusis Aldons J; Shi Weibin
Deficiency of inducible NO synthase reduces advanced but not early atherosclerosis in apolipoprotein E-deficient mice.
Life sciences 2006;79(6):525-31.
2006: Drake Thomas A; Schadt Eric E; Lusis Aldons J
Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice.
Mammalian genome : official journal of the International Mammalian Genome Society 2006;17(6):466-79.
2006: Brouwers Martijn C G J; Kono Naoko; van Greevenbroek Marleen M J; van der Kallen Carla J H; Lusis Aldons J; de Bruin Tjerk W A; Cantor Rita M
Longitudinal differences in familial combined hyperlipidemia quantitative trait loci.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(6):e118-9.
2006: Ghazalpour Anatole; Wang Xuping; Lusis Aldons J; Mehrabian Margarete
Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice.
Genetics 2006;173(2):943-51.
2006: Sheth S S; Bodnar J S; Ghazalpour A; Thipphavong C K; Tsutsumi S; Tward A D; Demant P; Kodama T; Aburatani H; Lusis A J
Hepatocellular carcinoma in Txnip-deficient mice.
Oncogene 2006;25(25):3528-36.
2006: Su Zhiguang; Li Yuhua; James Jessica C; Matsumoto Alan H; Helm Gregory A; Lusis Aldons J; Shi Weibin
Genetic linkage of hyperglycemia, body weight and serum amyloid-P in an intercross between C57BL/6 and C3H apolipoprotein E-deficient mice.
Human molecular genetics 2006;15(10):1650-8.
2006: Lum Pek Yee; Chen Yanqing; Zhu Jun; Lamb John; Melmed Shlomo; Wang Susanna; Drake Tom A; Lusis Aldons J; Schadt Eric E
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes.
Journal of neurochemistry 2006;97 Suppl 1():50-62.
2006: Lee Jenny C; Lusis Aldons J; Pajukanta Päivi
Familial combined hyperlipidemia: upstream transcription factor 1 and beyond.
Current opinion in lipidology 2006;17(2):101-9.
2006: Su Zhiguang; Li Yuhua; James Jessica C; McDuffie Marcia; Matsumoto Alan H; Helm Gregory A; Weber James L; Lusis Aldons J; Shi Weibin
Quantitative trait locus analysis of atherosclerosis in an intercross between C57BL/6 and C3H mice carrying the mutant apolipoprotein E gene.
Genetics 2006;172(3):1799-807.
2006: Wang Susanna; Yehya Nadir; Schadt Eric E; Wang Hui; Drake Thomas A; Lusis Aldons J
Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity.
PLoS genetics 2006;2(2):e15.
2006: Shih Diana M; Kast-Woelbern Heidi R; Wong Jack; Xia Yu-Rong; Edwards Peter A; Lusis Aldons J
A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids.
Journal of lipid research 2006;47(2):384-92.
2005: Ozer Egon A; Pezzulo Alejandro; Shih Diana M; Chun Carlene; Furlong Clement; Lusis Aldons J; Greenberg Everett P; Zabner Joseph
Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing.
FEMS microbiology letters 2005;253(1):29-37.
2005: Drake Thomas A; Schadt Eric E; Davis Richard C; Lusis Aldons J
Integrating genetic and gene expression data to study the metabolic syndrome and diabetes in mice.
American journal of therapeutics 2005;12(6):503-11.
2005: Mehrabian Margarete; Allayee Hooman; Stockton Jirina; Lum Pek Yee; Drake Thomas A; Castellani Lawrence W; Suh Michael; Armour Christopher; Edwards Stephen; Lamb John; Lusis Aldons J; Schadt Eric E
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits.
Nature genetics 2005;37(11):1224-33.
2005: Cervino Alessandra C; Li Guoya; Edwards Steve; Zhu Jun; Laurie Cathy; Tokiwa George; Lum Pek Yee; Wang Susanna; Castellani Lawrence W; Lusis Aldons J; Carlson Sonia; Sachs Alan B; Schadt Eric E
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels.
Genomics 2005;86(5):505-17.
2005: Davis Richard C; Schadt Eric E; Smith Desmond J; Hsieh Elena W Y; Cervino Alessandra C L; van Nas Atila; Rosales Melenie; Doss Sudheer; Meng Haijin; Allayee Hooman; Lusis Aldons J
A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background.
Genomics 2005;86(3):259-70.
2005: Huertas-Vazquez Adriana; Aguilar-Salinas Carlos; Lusis Aldons J; Cantor Rita M; Canizales-Quinteros Samuel; Lee Jenny C; Mariana-Nuñez Lizzette; Riba-Ramirez Roopa-Metha Laura; Jokiaho Anne; Tusie-Luna Teresa; Pajukanta Päivi
Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(9):1985-91.
2005: Furlong Clement E; Cole Toby B; Jarvik Gail P; Pettan-Brewer Christina; Geiss Gary K; Richter Rebecca J; Shih Diana M; Tward Aaron D; Lusis Aldons J; Costa Lucio G
Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants.
Neurotoxicology 2005;26(4):651-9.
2005: Cole Toby B; Walter Betsy J; Shih Diana M; Tward Aaron D; Lusis Aldons J; Timchalk Charles; Richter Rebecca J; Costa Lucio G; Furlong Clement E
Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism.
Pharmacogenetics and genomics 2005;15(8):589-98.
2005: Schadt Eric E; Lamb John; Yang Xia; Zhu Jun; Edwards Steve; Guhathakurta Debraj; Sieberts Solveig K; Monks Stephanie; Reitman Marc; Zhang Chunsheng; Lum Pek Yee; Leonardson Amy; Thieringer Rolf; Metzger Joseph M; Yang Liming; Castle John; Zhu Haoyuan; Kash Shera F; Drake Thomas A; Sachs Alan; Lusis Aldons J
An integrative genomics approach to infer causal associations between gene expression and disease.
Nature genetics 2005;37(7):710-7.
2005: Parks Brian W; Gambill Ginger P; Lusis Aldons J; Kabarowski Janusz H S
Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice.
Journal of lipid research 2005;46(7):1405-15.
2005: Nguyen Hal X; Lusis Aldons J; Tidball James G
Null mutation of myeloperoxidase in mice prevents mechanical activation of neutrophil lysis of muscle cell membranes in vitro and in vivo.
The Journal of physiology 2005;565(Pt 2):403-13.
2005: Doss Sudheer; Schadt Eric E; Drake Thomas A; Lusis Aldons J
Cis-acting expression quantitative trait loci in mice.
Genome research 2005;15(5):681-91.
2005: Davis Richard C; Schadt Eric E; Cervino Alessandra C L; Péterfy Miklós; Lusis Aldons J
Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and C57BLKS/J for loci contributing to diabetes and atherosclerosis susceptibility.
Diabetes 2005;54(4):1191-9.
2005: Sheth Sonal S; Castellani Lawrence W; Chari Soumya; Wagg Cory; Thipphavong Christopher K; Bodnar Jackie S; Tontonoz Peter; Attie Alan D; Lopaschuk Gary D; Lusis Aldons J
Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition.
Journal of lipid research 2005;46(1):123-34.
2005: Ghazalpour Anatole; Doss Sudheer; Sheth Sonal S; Ingram-Drake Leslie A; Schadt Eric E; Lusis Aldons J; Drake Thomas A
Genomic analysis of metabolic pathway gene expression in mice.
Genome biology 2005;6(7):R59.
2005: Furlong Clement E; Cole Toby B; Walter Betsy J; Shih Diana M; Tward Aaron; Lusis Aldons J; Timchalk Charles; Richter Rebecca J; Costa Lucio G
Paraoxonase 1 (PON1) status and risk of insecticide exposure.
Journal of biochemical and molecular toxicology 2005;19(3):182-3.
2004: Castellani Lawrence W; Gargalovic Peter; Febbraio Maria; Charugundla Sarada; Jien Ming-Len; Lusis Aldons J
Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II.
Journal of lipid research 2004;45(12):2377-87.
2004: Lusis Aldons J; Fogelman Alan M; Fonarow Gregg C
Genetic basis of atherosclerosis: part II: clinical implications.
Circulation 2004;110(14):2066-71.
2004: Wang Xuping; Gargalovic Peter; Wong Jack; Gu Jennifer L; Wu Xiaohui; Qi Hongxiu; Wen Pingzi; Xi Li; Tan Bing; Gogliotti Rocky; Castellani Lawrence W; Chatterjee Aurobindo; Lusis Aldons J
Hyplip2, a new gene for combined hyperlipidemia and increased atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1928-34.
2004: Cantor Rita M; de Bruin Tjerk; Kono Naoko; Napier Susan; van Nas Atila; Allayee Hooman; Lusis Aldons J
Quantitative trait loci for apolipoprotein B, cholesterol, and triglycerides in familial combined hyperlipidemia pedigrees.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1935-41.
2004: Ghazalpour Anatole; Doss Sudheer; Yang Xia; Aten Jason; Toomey Edward M; Van Nas Atila; Wang Susanna; Drake Thomas A; Lusis Aldons J
Thematic review series: The pathogenesis of atherosclerosis. Toward a biological network for atherosclerosis.
Journal of lipid research 2004;45(10):1793-805.
2004: Lusis Aldons J; Fogelman Alan M; Fonarow Gregg C
Genetic basis of atherosclerosis: part I: new genes and pathways.
Circulation 2004;110(13):1868-73.
2004: Rothfork Jacob M; Timmins Graham S; Harris Michael N; Chen Xian; Lusis Aldons J; Otto Michael; Cheung Ambrose L; Gresham Hattie D
Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(38):13867-72.
2004: Donnelly Kerry L; Margosian Mark R; Sheth Sonal S; Lusis Aldons J; Parks Elizabeth J
Increased lipogenesis and fatty acid reesterification contribute to hepatic triacylglycerol stores in hyperlipidemic Txnip-/- mice.
The Journal of nutrition 2004;134(6):1475-80.
2004: Brown Morry D; Jin Li; Jien Ming-Len; Matsumoto Alan H; Helm Gregory A; Lusis Aldons J; Frank Joy S; Shi Weibin
Lipid retention in the arterial wall of two mouse strains with different atherosclerosis susceptibility.
Journal of lipid research 2004;45(6):1155-61.
2004: Navab Mohamad; Ananthramaiah G M; Reddy Srinivasa T; Van Lenten Brian J; Ansell Benjamin J; Fonarow Gregg C; Vahabzadeh Kambiz; Hama Susan; Hough Greg; Kamranpour Naeimeh; Berliner Judith A; Lusis Aldons J; Fogelman Alan M
The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL.
Journal of lipid research 2004;45(6):993-1007.
2004: Hui To Yuen; Sheth Sonal S; Diffley J Matthew; Potter Douglas W; Lusis Aldons J; Attie Alan D; Davis Roger A
Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals.
The Journal of biological chemistry 2004;279(23):24387-93.
2004: Shi Weibin; Wang Xuping; Wong Jack; Hedrick Catherine C; Wong Howard; Castellani Lawrence W; Lusis Aldons J
Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice.
Biochemical and biophysical research communications 2004;317(1):223-9.
2004: Mar Rebecca; Pajukanta Päivi; Allayee Hooman; Groenendijk Martine; Dallinga-Thie Geesje; Krauss Ronald M; Sinsheimer Janet S; Cantor Rita M; de Bruin Tjerk W A; Lusis Aldons J
Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia.
Circulation research 2004;94(7):993-9.
2004: Pajukanta Päivi; Lilja Heidi E; Sinsheimer Janet S; Cantor Rita M; Lusis Aldons J; Gentile Massimiliano; Duan Xiaoqun Joyce; Soro-Paavonen Aino; Naukkarinen Jussi; Saarela Janna; Laakso Markku; Ehnholm Christian; Taskinen Marja-Riitta; Peltonen Leena
Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).
Nature genetics 2004;36(4):371-6.
2004: Liu Dahai; Singh Ram Pyare; Khan Arshad H; Lusis Aldons J; Davis Richard C; Smith Desmond J
Mapping behavioral traits by use of genome-tagged mice.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2004;12(2):158-65.
2004: Welch Carrie L; Bretschger Sara; Wen Ping-Zi; Mehrabian Margarete; Latib Nashat; Fruchart-Najib Jamila; Fruchart Jean Charles; Myrick Christy; Lusis Aldons J
Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain.
Physiological genomics 2004;17(1):48-59.
2004: Estrada-Smith Daria; Castellani Lawrence W; Wong Howard; Wen Ping-Zi; Chui Aileen; Lusis Aldons J; Davis Richard C
Dissection of multigenic obesity traits in congenic mouse strains.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(1):14-22.
2004: Dwyer James H; Allayee Hooman; Dwyer Kathleen M; Fan Jing; Wu Huiyun; Mar Rebecca; Lusis Aldons J; Mehrabian Margarete
Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis.
The New England journal of medicine 2004;350(1):29-37.
2004: Lusis Aldons J; Mar Rebecca; Pajukanta Paivi
Genetics of atherosclerosis.
Annual review of genomics and human genetics 2004;5():189-218.
2003: MacLellan W Robb; Lusis Aldons J
Dilated cardiomyopathy: learning to live with yourself.
Nature medicine 2003;9(12):1455-6.
2003: Liu Dahai; Singh Ram Pyare; Khan Arshad H; Bhavsar Kinnar; Lusis Aldons J; Davis Richard C; Smith Desmond J
Identifying loci for behavioral traits using genome-tagged mice.
Journal of neuroscience research 2003;74(4):562-9.
2003: Lusis Aldons J
Genetic factors in cardiovascular disease. 10 questions.
Trends in cardiovascular medicine 2003;13(8):309-16.
2003: Shi Weibin; Brown Morry D; Wang Xuping; Wong Jack; Kallmes David F; Matsumoto Alan H; Helm Gregory A; Drake Thomas A; Lusis Aldons J
Genetic backgrounds but not sizes of atherosclerotic lesions determine medial destruction in the aortic root of apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(10):1901-6.
2003: Allayee Hooman; Ghazalpour Anatole; Lusis Aldons J
Using mice to dissect genetic factors in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(9):1501-9.
2003: Araujo Jesus A; Meng Lingzhong; Tward Aaron D; Hancock Wayne W; Zhai Yuan; Lee Annie; Ishikawa Kazunobu; Iyer Suhasini; Buelow Roland; Busuttil Ronald W; Shih Diana M; Lusis Aldons J; Kupiec-Weglinski Jerzy W
Systemic rather than local heme oxygenase-1 overexpression improves cardiac allograft outcomes in a new transgenic mouse.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1572-80.
2003: Colinayo Veronica V; Qiao Jian-Hua; Wang Xuping; Krass Kelly L; Schadt Eric; Lusis Aldons J; Drake Thomas A
Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(7):464-71.
2003: Krass Kelly L; Colinayo Veronica; Ghazalpour Anatole; Vinters Harry V; Lusis Aldons J; Drake Thomas A
Genetic loci contributing to age-related hippocampal lesions in mice.
Neurobiology of disease 2003;13(2):102-8.
2003: Cole Toby B; Jampsa Rachel L; Walter Betsy J; Arndt Tara L; Richter Rebecca J; Shih Diana M; Tward Aaron; Lusis Aldons J; Jack Rhona M; Costa Lucio G; Furlong Clement E
Expression of human paraoxonase (PON1) during development.
Pharmacogenetics 2003;13(6):357-64.
2003: Allayee Hooman; Castellani Lawrence W; Cantor Rita M; de Bruin Tjerk W A; Lusis Aldons J
Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia.
Circulation research 2003;92(11):1262-7.
2003: Pajukanta Päivi; Allayee Hooman; Krass Kelly L; Kuraishy Ali; Soro Aino; Lilja Heidi E; Mar Rebecca; Taskinen Marja-Riitta; Nuotio Ilpo; Laakso Markku; Rotter Jerome I; de Bruin Tjerk W A; Cantor Rita M; Lusis Aldons J; Peltonen Leena
Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q.
American journal of human genetics 2003;72(4):903-17.
2003: Schadt Eric E; Monks Stephanie A; Drake Thomas A; Lusis Aldons J; Che Nam; Colinayo Veronica; Ruff Thomas G; Milligan Stephen B; Lamb John R; Cavet Guy; Linsley Peter S; Mao Mao; Stoughton Roland B; Friend Stephen H
Genetics of gene expression surveyed in maize, mouse and man.
Nature 2003;422(6929):297-302.
2003: Nishimura Ichiro; Drake Thomas A; Lusis Aldons J; Lyons Karen M; Nadeau Joseph H; Zernik Joseph
ENU large-scale mutagenesis and quantitative trait linkage (QTL) analysis in mice: novel technologies for searching polygenetic determinants of craniofacial abnormalities.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 2003;14(5):320-30.
2002: Smith Jeffrey B; Wadleigh David J; Xia Yu-Rong; Mar Rebecca A; Herschman Harvey R; Lusis Aldons J
Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5.
Immunogenetics 2002;54(8):599-603.
2002: Attie Alan D; Krauss Ronald M; Gray-Keller Mark P; Brownlie Alison; Miyazaki Makoto; Kastelein John J; Lusis Aldons J; Stalenhoef Anton F H; Stoehr Jonathan P; Hayden Michael R; Ntambi James M
Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia.
Journal of lipid research 2002;43(11):1899-907.
2002: Smith Desmond J; Lusis Aldons J
The allelic structure of common disease.
Human molecular genetics 2002;11(20):2455-61.
2002: Tangirala Rajendra K; Bischoff Eric D; Joseph Sean B; Wagner Brandee L; Walczak Robert; Laffitte Bryan A; Daige Chris L; Thomas Diane; Heyman Richard A; Mangelsdorf David J; Wang Xuping; Lusis Aldons J; Tontonoz Peter; Schulman Ira G
Identification of macrophage liver X receptors as inhibitors of atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11896-901.
2002: Mehrabian Margarete; Allayee Hooman; Wong Jack; Shi Weibin; Wang Xu-Ping; Shaposhnik Zory; Funk Colin D; Lusis Aldons J;
Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice.
Circulation research 2002;91(2):120-6.
2002: Tward Aaron; Xia Yu-Rong; Wang Xu-Ping; Shi Yi-Shou; Park Christina; Castellani Lawrence W; Lusis Aldons J; Shih Diana M
Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice.
Circulation 2002;106(4):484-90.
2002: Colinayo Veronica V; Qiao Jian-Hua; Demant Peter; Krass Kelly; Lusis Aldons J; Drake Thomas A
Genetic characterization of the Dyscalc locus.
Mammalian genome : official journal of the International Mammalian Genome Society 2002;13(6):283-8.
2002: Eiserich Jason P; Baldus Stephan; Brennan Marie-Luise; Ma Wenxin; Zhang Chunxiang; Tousson Albert; Castro Laura; Lusis Aldons J; Nauseef William M; White C Roger; Freeman Bruce A
Myeloperoxidase, a leukocyte-derived vascular NO oxidase.
Science (New York, N.Y.) 2002;296(5577):2391-4.
2002: Joseph Sean B; McKilligin Elaine; Pei Liming; Watson Michael A; Collins Alan R; Laffitte Bryan A; Chen Mingyi; Noh Grace; Goodman Joanne; Hagger Graham N; Tran Jonathan; Tippin Tim K; Wang Xuping; Lusis Aldons J; Hsueh Willa A; Law Ronald E; Collins Jon L; Willson Timothy M; Tontonoz Peter
Synthetic LXR ligand inhibits the development of atherosclerosis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(11):7604-9.
2002: Allayee Hooman; Krass Kelly L; Pajukanta Päivi; Cantor Rita M; van der Kallen Carla J H; Mar Rebecca; Rotter Jerome I; de Bruin Tjerk W A; Peltonen Leena; Lusis Aldons J
Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia.
Circulation research 2002;90(8):926-31.
2002: Brennan Marie-Luise; Wu Weijia; Fu Xiaoming; Shen Zhongzhu; Song Wei; Frost Heather; Vadseth Caryn; Narine Laura; Lenkiewicz Elizabeth; Borchers Michael T; Lusis Aldons J; Lee James J; Lee Nancy A; Abu-Soud Husam M; Ischiropoulos Harry; Hazen Stanley L
A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species.
The Journal of biological chemistry 2002;277(20):17415-27.
2002: Shi Weibin; Wang Xuping; Shih Diana M; Laubach Victor E; Navab Mohamad; Lusis Aldons J
Paradoxical reduction of fatty streak formation in mice lacking endothelial nitric oxide synthase.
Circulation 2002;105(17):2078-82.
2002: Shi Weibin; Wang Xuping; Tangchitpiyanond Khan; Wong Jack; Shi Yishou; Lusis Aldons J
Atherosclerosis in C3H/HeJ mice reconstituted with apolipoprotein E-null bone marrow.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(4):650-5.
2002: Gukovskaya Anna S; Vaquero Eva; Zaninovic Vjekoslav; Gorelick Fred S; Lusis Aldons J; Brennan Marie-Luise; Holland Steven; Pandol Stephen J
Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis.
Gastroenterology 2002;122(4):974-84.
2002: Sheth Sonal S; Deluna Andres; Allayee Hooman; Lusis Aldons J
Understanding atherosclerosis through mouse genetics.
Current opinion in lipidology 2002;13(2):181-9.
2002: Miyake Jon H; Duong-Polk Xuandao T; Taylor John M; Du Emma Z; Castellani Lawrence W; Lusis Aldons J; Davis Roger A
Transgenic expression of cholesterol-7-alpha-hydroxylase prevents atherosclerosis in C57BL/6J mice.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(1):121-6.
2002: Bodnar Jackie S; Chatterjee Aurobindo; Castellani Lawrence W; Ross David A; Ohmen Jeffrey; Cavalcoli James; Wu Chenyan; Dains Katherine M; Catanese Joe; Chu Michael; Sheth Sonal S; Charugundla Kanti; Demant Peter; West David B; de Jong Pieter; Lusis Aldons J
Positional cloning of the combined hyperlipidemia gene Hyplip1.
Nature genetics 2002;30(1):110-6.
2001: Baldus S; Eiserich J P; Mani A; Castro L; Figueroa M; Chumley P; Ma W; Tousson A; White C R; Bullard D C; Brennan M L; Lusis A J; Moore K P; Freeman B A
Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration.
The Journal of clinical investigation 2001;108(12):1759-70.
2001: Allayee H; de Bruin T W; Michelle Dominguez K; Cheng L S; Ipp E; Cantor R M; Krass K L; Keulen E T; Aouizerat B E; Lusis A J; Rotter J I
Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p.
Hypertension 2001;38(4):773-8.
2001: Karlsson M; Reue K; Xia Y R; Lusis A J; Langin D; Tornqvist H; Holm C
Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene.
Gene 2001;272(1-2):11-8.
2001: Mehrabian M; Wong J; Wang X; Jiang Z; Shi W; Fogelman A M; Lusis A J
Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia.
Circulation research 2001;89(2):125-30.
2001: Iakoubova O A; Olsson C L; Dains K M; Ross D A; Andalibi A; Lau K; Choi J; Kalcheva I; Cunanan M; Louie J; Nimon V; Machrus M; Bentley L G; Beauheim C; Silvey S; Cavalcoli J; Lusis A J; West D B
Genome-tagged mice (GTM): two sets of genome-wide congenic strains.
Genomics 2001;74(1):89-104.
2001: Van Lenten B J; Navab M; Shih D; Fogelman A M; Lusis A J
The role of high-density lipoproteins in oxidation and inflammation.
Trends in cardiovascular medicine 2001;11(3-4):155-61.
2001: Drake T A; Schadt E; Hannani K; Kabo J M; Krass K; Colinayo V; Greaser L E; Goldin J; Lusis A J
Genetic loci determining bone density in mice with diet-induced atherosclerosis.
Physiological genomics 2001;5(4):205-15.
2001: Reddy S T; Wadleigh D J; Grijalva V; Ng C; Hama S; Gangopadhyay A; Shih D M; Lusis A J; Navab M; Fogelman A M
Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(4):542-7.
2001: Navab M; Berliner J A; Subbanagounder G; Hama S; Lusis A J; Castellani L W; Reddy S; Shih D; Shi W; Watson A D; Van Lenten B J; Vora D; Fogelman A M
HDL and the inflammatory response induced by LDL-derived oxidized phospholipids.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(4):481-8.
2001: Hedrick C C; Castellani L W; Wong H; Lusis A J
In vivo interactions of apoA-II, apoA-I, and hepatic lipase contributing to HDL structure and antiatherogenic functions.
Journal of lipid research 2001;42(4):563-70.
2001: Pajukanta P; Bodnar J S; Sallinen R; Chu M; Airaksinen T; Xiao Q; Castellani L W; Sheth S S; Wessman M; Palotie A; Sinsheimer J S; Demant P; Lusis A J; Peltonen L
Fine mapping of Hyplip1 and the human homolog, a potential locus for FCHL.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(3):238-45.
2001: Castellani L W; Goto A M; Lusis A J
Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistance.
Diabetes 2001;50(3):643-51.
2001: Brennan M L; Anderson M M; Shih D M; Qu X D; Wang X; Mehta A C; Lim L L; Shi W; Hazen S L; Jacob J S; Crowley J R; Heinecke J W; Lusis A J
Increased atherosclerosis in myeloperoxidase-deficient mice.
The Journal of clinical investigation 2001;107(4):419-30.
2000: Li W F; Costa L G; Richter R J; Hagen T; Shih D M; Tward A; Lusis A J; Furlong C E
Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds.
Pharmacogenetics 2000;10(9):767-79.
2000: Allayee H; Laffitte B A; Lusis A J
Biochemistry. An absorbing study of cholesterol.
Science (New York, N.Y.) 2000;290(5497):1709-11.
2000: Mehrabian M; Castellani L W; Wen P Z; Wong J; Rithaporn T; Hama S Y; Hough G P; Johnson D; Albers J J; Mottino G A; Frank J S; Navab M; Fogelman A M; Lusis A J
Genetic control of HDL levels and composition in an interspecific mouse cross (CAST/Ei x C57BL/6J).
Journal of lipid research 2000;41(12):1936-46.
2000: Shi W; Wang X; Wang N J; McBride W H; Lusis A J
Effect of macrophage-derived apolipoprotein E on established atherosclerosis in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(10):2261-6.
2000: Lusis A J
Atherosclerosis.
Nature 2000;407(6801):233-41.
2000: Furlong C E; Li W F; Brophy V H; Jarvik G P; Richter R J; Shih D M; Lusis A J; Costa L G
The PON1 gene and detoxication.
Neurotoxicology 2000;21(4):581-7.
2000: Shi W; Haberland M E; Jien M L; Shih D M; Lusis A J
Endothelial responses to oxidized lipoproteins determine genetic susceptibility to atherosclerosis in mice.
Circulation 2000;102(1):75-81.
2000: Widney D P; Xia Y R; Lusis A J; Smith J B
The murine chemokine CXCL11 (IFN-inducible T cell alpha chemoattractant) is an IFN-gamma- and lipopolysaccharide-inducible glucocorticoid-attenuated response gene expressed in lung and other tissues during endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(12):6322-31.
2000: Shih D M; Xia Y R; Wang X P; Miller E; Castellani L W; Subbanagounder G; Cheroutre H; Faull K F; Berliner J A; Witztum J L; Lusis A J
Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis.
The Journal of biological chemistry 2000;275(23):17527-35.
2000: Shi W; Wang N J; Shih D M; Sun V Z; Wang X; Lusis A J
Determinants of atherosclerosis susceptibility in the C3H and C57BL/6 mouse model: evidence for involvement of endothelial cells but not blood cells or cholesterol metabolism.
Circulation research 2000;86(10):1078-84.
2000: Mouzeyan A; Choi J; Allayee H; Wang X; Sinsheimer J; Phan J; Castellani L W; Reue K; Lusis A J; Davis R C
A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2.
Journal of lipid research 2000;41(4):573-82.
2000: Furlong C E; Li W F; Richter R J; Shih D M; Lusis A J; Alleva E; Costa L G
Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1).
Neurotoxicology 2000;21(1-2):91-100.
2000: Allayee H; Dominguez K M; Aouizerat B E; Krauss R M; Rotter J I; Lu J; Cantor R M; de Bruin T W; Lusis A J
Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia.
Journal of lipid research 2000;41(2):245-52.
1999: Aouizerat B E; Allayee H; Cantor R M; Dallinga-Thie G M; Lanning C D; de Bruin T W; Lusis A J; Rotter J I
Linkage of a candidate gene locus to familial combined hyperlipidemia: lecithin:cholesterol acyltransferase on 16q.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(11):2730-6.
1999: Aouizerat B E; Allayee H; Cantor R M; Davis R C; Lanning C D; Wen P Z; Dallinga-Thie G M; de Bruin T W; Rotter J I; Lusis A J
A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11.
American journal of human genetics 1999;65(2):397-412.
1999: Costa L G; Li W F; Richter R J; Shih D M; Lusis A; Furlong C E
The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism.
Chemico-biological interactions 1999;119-120():429-38.
1999: Leitinger N; Watson A D; Hama S Y; Ivandic B; Qiao J H; Huber J; Faull K F; Grass D S; Navab M; Fogelman A M; de Beer F C; Lusis A J; Berliner J A
Role of group II secretory phospholipase A2 in atherosclerosis: 2. Potential involvement of biologically active oxidized phospholipids.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1291-8.
1999: Ivandic B; Castellani L W; Wang X P; Qiao J H; Mehrabian M; Navab M; Fogelman A M; Grass D S; Swanson M E; de Beer M C; de Beer F; Lusis A J
Role of group II secretory phospholipase A2 in atherosclerosis: 1. Increased atherogenesis and altered lipoproteins in transgenic mice expressing group IIa phospholipase A2.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1284-90.
1999: Aouizerat B E; Allayee H; Bodnar J; Krass K L; Peltonen L; de Bruin T W; Rotter J I; Lusis A J
Novel genes for familial combined hyperlipidemia.
Current opinion in lipidology 1999;10(2):113-22.
1999: Escary J L; Choy H A; Reue K; Wang X P; Castellani L W; Glass C K; Lusis A J; Schotz M C
Paradoxical effect on atherosclerosis of hormone-sensitive lipase overexpression in macrophages.
Journal of lipid research 1999;40(3):397-404.
1999: Shih P T; Brennan M L; Vora D K; Territo M C; Strahl D; Elices M J; Lusis A J; Berliner J A
Blocking very late antigen-4 integrin decreases leukocyte entry and fatty streak formation in mice fed an atherogenic diet.
Circulation research 1999;84(3):345-51.
1998: Gu L; Weinreb A; Wang X P; Zack D J; Qiao J H; Weisbart R; Lusis A J
Genetic determinants of autoimmune disease and coronary vasculitis in the MRL-lpr/lpr mouse model of systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6999-7006.
1998: Furlong C E; Li W F; Costa L G; Richter R J; Shih D M; Lusis A J
Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism.
Neurotoxicology 1998;19(4-5):645-50.
1998: Allayee H; Aouizerat B E; Cantor R M; Dallinga-Thie G M; Krauss R M; Lanning C D; Rotter J I; Lusis A J; de Bruin T W
Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype.
American journal of human genetics 1998;63(2):577-85.
1998: Shih D M; Gu L; Xia Y R; Navab M; Li W F; Hama S; Castellani L W; Furlong C E; Costa L G; Fogelman A M; Lusis A J
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis.
Nature 1998;394(6690):284-7.
1998: Jiang Z; Shih D M; Xia Y R; Lusis A J; de Beer F C; de Villiers W J; van der Westhuyzen D R; de Beer M C
Structure, organization, and chromosomal mapping of the gene encoding macrosialin, a macrophage-restricted protein.
Genomics 1998;50(2):199-205.
1998: Rajavashisth T; Qiao J H; Tripathi S; Tripathi J; Mishra N; Hua M; Wang X P; Loussararian A; Clinton S; Libby P; Lusis A
Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor- deficient mice.
The Journal of clinical investigation 1998;101(12):2702-10.
1998: Mehrabian M; Wen P Z; Fisler J; Davis R C; Lusis A J
Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.
The Journal of clinical investigation 1998;101(11):2485-96.
1998: Castellani L W; Weinreb A; Bodnar J; Goto A M; Doolittle M; Mehrabian M; Demant P; Lusis A J
Mapping a gene for combined hyperlipidaemia in a mutant mouse strain.
Nature genetics 1998;18(4):374-7.
1998: Tabor D E; Xia Y R; Mehrabian M; Edwards P A; Lusis A J
A cluster of stearoyl CoA desaturase genes, Scd1 and Scd2, on mouse chromosome 19.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(4):341-2.
1998: Briquet-Laugier V; Xia Y R; Rooke K; Mehrabian M; Lusis A J; Doolittle M H
Mapping of three members of the mouse protein disulfide isomerase family.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(2):176-7.
1998: Welch C L; Xia Y R; Edwards P A; Lusis A J; Ericsson J
Assignment of Gpam to distal mouse chromosome 19 by linkage analysis.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(1):93.
1997: Welch C L; Xia Y R; Gu L J; Machleder D; Mehrabian M; Wen P Z; Webb N; de Villiers W J; van der Westhuyzen D; Lusis A J
Srb1 maps to mouse chromosome 5 in a region harboring putative QTLs for plasma lipoprotein levels.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(12):942-4.
1997: de Beer F C; de Beer M C; van der Westhuyzen D R; Castellani L W; Lusis A J; Swanson M E; Grass D S
Secretory non-pancreatic phospholipase A2: influence on lipoprotein metabolism.
Journal of lipid research 1997;38(11):2232-9.
1997: Fyfe A I; Rothenberg L S; DeBeer F C; Cantor R M; Rotter J I; Lusis A J
Association between serum amyloid A proteins and coronary artery disease: evidence from two distinct arteriosclerotic processes.
Circulation 1997;96(9):2914-9.
1997: Klingenspor M; Bodnar J; Welch C; Xia Y R; Lusis A J; Reue K
Localization of ubiquitin gene family members to mouse chromosomes 5, 11, and 18.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(10):789-90.
1997: Lembertas A V; Pérusse L; Chagnon Y C; Fisler J S; Warden C H; Purcell-Huynh D A; Dionne F T; Gagnon J; Nadeau A; Lusis A J; Bouchard C
Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.
The Journal of clinical investigation 1997;100(5):1240-7.
1997: Ishikawa K; Navab M; Leitinger N; Fogelman A M; Lusis A J
Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL.
The Journal of clinical investigation 1997;100(5):1209-16.
1997: Welch C L; Xia Y R; Hong H; Stallcup M R; Lusis A J
Localization of the mouse glucocorticoid receptor-interacting protein 1 gene (Grip1) to proximal chromosome 1 by linkage analysis.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(8):620-1.
1997: Castellani L W; Navab M; Van Lenten B J; Hedrick C C; Hama S Y; Goto A M; Fogelman A M; Lusis A J
Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles.
The Journal of clinical investigation 1997;100(2):464-74.
1997: Klingenspor M; Bodnar J; Xia Y R; Welch C; Lusis A J; Reue K
Localization of profilin-1 (Pfn1) and a related sequence (Pfn1-rs) to mouse chromosomes 11 and 15 respectively.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(7):539-40.
1997: Qiao J H; Tripathi J; Mishra N K; Cai Y; Tripathi S; Wang X P; Imes S; Fishbein M C; Clinton S K; Libby P; Lusis A J; Rajavashisth T B
Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice.
The American journal of pathology 1997;150(5):1687-99.
1997: Navab M; Hama-Levy S; Van Lenten B J; Fonarow G C; Cardinez C J; Castellani L W; Brennan M L; Lusis A J; Fogelman A M; La Du B N
Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio.
The Journal of clinical investigation 1997;99(8):2005-19.
1997: Cohen R D; Castellani L W; Qiao J H; Van Lenten B J; Lusis A J; Reue K
Reduced aortic lesions and elevated high density lipoprotein levels in transgenic mice overexpressing mouse apolipoprotein A-IV.
The Journal of clinical investigation 1997;99(8):1906-16.
1997: Machleder D; Ivandic B; Welch C; Castellani L; Reue K; Lusis A J
Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism.
The Journal of clinical investigation 1997;99(6):1406-19.
1997: Rooke K; Briquet-Laugier V; Xia Y R; Lusis A J; Doolittle M H
Mapping of the gene for calreticulin (Calr) to mouse chromosome 8.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(11):870-1.

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