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Matthias Lutolf

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TOP 3
Steffen Cosson; Simone Allazetta; Matthias P Lutolf
Patterning of cell-instructive hydrogels by hydrodynamic flow focusing.
Simone Allazetta; Tanja C Hausherr; Matthias P Lutolf
Microfluidic synthesis of cell-type-specific artificial extracellular matrix hydrogels.
Mikaël Martino; Adrian Ranga; Priscilla S Briquez; Matthias P Lutolf; Jeffrey A Hubbell
Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix.

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All Publications

2013: Steffen Cosson; Simone Allazetta; Matthias P Lutolf
Patterning of cell-instructive hydrogels by hydrodynamic flow focusing.
Lab on a chip 2013;13(11):2099-105.
2013: Simone Allazetta; Tanja C Hausherr; Matthias P Lutolf
Microfluidic synthesis of cell-type-specific artificial extracellular matrix hydrogels.
Biomacromolecules 2013;14(4):1122-31.
2013: Mikaël Martino; Adrian Ranga; Priscilla S Briquez; Matthias P Lutolf; Jeffrey A Hubbell
Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(12):4563-8.
2013: Philipp S Lienemann; Matthias P Lutolf; Ana Sala; Franz E Weber; Wilfried Weber; Hanna M Wischhusen; Roland Zimmermann; Maria Karlsson; Martin Ehrbar
A versatile approach to engineering biomolecule-presenting cellular microenvironments.
Advanced healthcare materials 2013;2(2):292-6.
2013: Marta Roccio; Daniel Sage; Daniel Schmitter; Marlen Knobloch; Yuya Okawa; Matthias P Lutolf
Predicting stem cell fate changes by differential cell cycle progression patterns.
Development (Cambridge, England) 2013;140(2):459-70.
2013: Marlen Knobloch; Werner J Kovacs; Matthias P Lutolf; Raquel A C Machado; Marta Roccio; Clay F Semenkovich; Ueli Suter; Carolin von Schoultz; Nicola Zamboni; Luis Zurkirchen; Marcos J Arauzo-Bravo; Simon M G Braun; Ozlem Karalay; Sebastian Jessberger
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis.
Nature 2013;493(7431):226-30.
2012: Philipp S Lienemann; Matthias P Lutolf; Martin Ehrbar
Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration.
Advanced drug delivery reviews 2012;64(12):1078-89.
2012: Stefan A Kobel; Olivier Burri; Mukul Girotra; Alexandra Griffa; Arne Seitz; Matthias P Lutolf
Automated analysis of single stem cells in microfluidic traps.
Lab on a chip 2012;12(16):2843-9.
2012: Colette A Bichsel; Marco G Cecchini; Samy Gobaa; Stefan Kobel; Chiara Secondini; George N Thalmann; Matthias P Lutolf
Diagnostic microchip to assay 3D colony-growth potential of captured circulating tumor cells.
Lab on a chip 2012;12(13):2313-6.
2012: Nicola Vannini; Alessandra Griffa; Stefan Kobel; Olaia Naveiras; Aline Roch; Matthias P Lutolf
Identification of in vitro HSC fate regulators by differential lipid raft clustering.
Cell cycle (Georgetown, Tex.) 2012;11(8):1535-43.
2012: Marta Roccio; Samy Gobaa; Matthias P Lutolf
High-throughput clonal analysis of neural stem cells in microarrayed artificial niches.
Integrative biology : quantitative biosciences from nano to macro 2012;4(4):391-400.
2012: Adrian Ranga; Matthias P Lutolf
High-throughput approaches for the analysis of extrinsic regulators of stem cell fate.
Current opinion in cell biology 2012;24(2):236-44.
2012: Matthias P Lutolf
Materials science: Cell environments programmed with light.
Nature 2012;482(7386):477-8.
2012: Hans M Larsson; Seung Tae Lee; Matthias P Lutolf; Marta Roccio; Diana Velluto; Peter Frey; Jeffrey A Hubbell
Sorting live stem cells based on Sox2 mRNA expression.
PloS one 2012;7(11):e49874.
2012: Maria Håkanson; Stefan Kobel; Matthias P Lutolf; Marcus Textor; Edna Cukierman; Mirren Charnley
Controlled breast cancer microarrays for the deconvolution of cellular multilayering and density effects upon drug responses.
PloS one 2012;7(6):e40141.
2012: Stefan A Kobel; Matthias P Lutolf
Fabrication of PEG hydrogel microwell arrays for high-throughput single stem cell culture and analysis.
Methods in molecular biology (Clifton, N.J.) 2012;811():101-12.
2011: Ana Sala; Janos Vörös; Martin Ehrbar; Patrick Hänseler; Matthias P Lutolf; Adrian Ranga; Franz E Weber
Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning.
Integrative biology : quantitative biosciences from nano to macro 2011;3(11):1102-11.
2011: Samy Gobaa; Sylke Hoehnel; Stefan Kobel; Andrea Negro; Marta Roccio; Matthias P Lutolf
Artificial niche microarrays for probing single stem cell fate in high throughput.
Nature methods 2011;8(11):949-55.
2011: Stefan Kobel; Matthias P Lutolf
Biomaterials meet microfluidics: building the next generation of artificial niches.
Current opinion in biotechnology 2011;22(5):690-7.
2011: Jeroen Rouwkema; Gordana Vunjak-Novakovic; Susan Gibbs; Matthias P Lutolf; Ivan Martin; Jos Malda
In vitro platforms for tissue engineering: implications for basic research and clinical translation.
Journal of tissue engineering and regenerative medicine 2011;5(8):e164-7.
2011: Natalia Nieto; Matthias P Lutolf
Extracellular matrix bioengineering and systems biology approaches in liver disease.
Systems and synthetic biology 2011;5(1-2):11-20.
2011: Martin Ehrbar; A Sala; P Lienemann; A Ranga; K Mosiewicz; Anne Greet Bittermann; Simone C Rizzi; Franz Weber; Matthias P Lutolf
Elucidating the role of matrix stiffness in 3D cell migration and remodeling.
Biophysical journal 2011;100(2):284-93.
2011: Simone Allazetta; Steffen Cosson; Matthias P Lutolf
Programmable microfluidic patterning of protein gradients on hydrogels.
Chemical communications (Cambridge, England) 2011;47(1):191-3.
2010: Daniela Loessner; Kathryn S Stok; Matthias P Lutolf; Dietmar W Hutmacher; Judith A Clements; Simone C Rizzi
Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells.
Biomaterials 2010;31(32):8494-506.
2010: Katrin Bott; Zee Upton; Karsten Schrobback; Martin Ehrbar; Jeffrey A Hubbell; Matthias P Lutolf; Simone C Rizzi
The effect of matrix characteristics on fibroblast proliferation in 3D gels.
Biomaterials 2010;31(32):8454-64.
2010: P M Gilbert; K L Havenstrite; K E G Magnusson; A Sacco; N A Leonardi; Peggy E Kraft; N K Nguyen; S Thrun; Matthias P Lutolf; Helen M Blau
Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture.
Science (New York, N.Y.) 2010;329(5995):1078-81.
2010: Yun Suk Jo; Simone C Rizzi; Martin Ehrbar; Franz E Weber; Jeffrey A Hubbell; Matthias P Lutolf
Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides.
Journal of biomedical materials research. Part A 2010;93(3):870-7.
2010: Katarzyna A Mosiewicz; Kai Johnsson; Matthias P Lutolf
Phosphopantetheinyl transferase-catalyzed formation of bioactive hydrogels for tissue engineering.
Journal of the American Chemical Society 2010;132(17):5972-4.
2009: Mirren Charnley; Marcus Textor; Ali Khademhosseini; Matthias P Lutolf
Integration column: microwell arrays for mammalian cell culture.
Integrative biology : quantitative biosciences from nano to macro 2009;1(11-12):625-34.
2009: Matthias P Lutolf; Penney M Gilbert; Helen M Blau
Designing materials to direct stem-cell fate.
Nature 2009;462(7272):433-41.
2009: Matthias P Lutolf; Helen M Blau
Artificial stem cell niches.
Advanced materials (Deerfield Beach, Fla.) 2009;21(32-33):3255-68.
2009: Stefan Kobel; Monika Limacher; Samy Gobaa; Thierry Laroche; Matthias P Lutolf
Micropatterning of hydrogels by soft embossing.
Langmuir : the ACS journal of surfaces and colloids 2009;25(15):8774-9.
2009: Matthias P Lutolf
Biomaterials: Spotlight on hydrogels.
Nature materials 2009;8(6):451-3.
2009: Matthias P Lutolf
Integration column: artificial ECM: expanding the cell biology toolbox in 3D.
Integrative biology : quantitative biosciences from nano to macro 2009;1(3):235-41.
2009: Matthias P Lutolf; Regis Doyonnas; Karen Havenstrite; Kassie Koleckar; Helen M Blau
Perturbation of single hematopoietic stem cell fates in artificial niches.
Integrative biology : quantitative biosciences from nano to macro 2009;1(1):59-69.
2008: Myriam Cordey; Monika Limacher; Stefan Kobel; Verdon Taylor; Matthias P Lutolf
Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays.
Stem cells (Dayton, Ohio) 2008;26(10):2586-94.
2008: Thomas Kraehenbuehl; Prisca Zammaretti; André J Van der Vlies; Ronald G Schoenmakers; Matthias P Lutolf; Marisa E Jaconi; Jeffrey A Hubbell
Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: systematic modulation of a synthetic cell-responsive PEG-hydrogel.
Biomaterials 2008;29(18):2757-66.
2007: Martin Ehrbar; Simone C Rizzi; Ronald G Schoenmakers; Blanca San Miguel; Jeffrey A Hubbell; Franz Weber; Matthias P Lutolf
Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions.
Biomacromolecules 2007;8(10):3000-7.
2007: George Raeber; Matthias P Lutolf; Jeffrey A Hubbell
Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs.
Acta biomaterialia 2007;3(5):615-29.
2007: Martin Ehrbar; Simone C Rizzi; Ruslan Hlushchuk; Valentin Djonov; Andreas H Zisch; Jeffrey A Hubbell; Franz Weber; Matthias P Lutolf
Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering.
Biomaterials 2007;28(26):3856-66.
2005: George Raeber; Matthias P Lutolf; Jeffrey A Hubbell
Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration.
Biophysical journal 2005;89(2):1374-88.
2005: Matthias P Lutolf; Jeffrey A Hubbell
Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering.
Nature biotechnology 2005;23(1):47-55.
2005: M H Fittkau; Peter Zilla; Deon Bezuidenhout; Matthias P Lutolf; Paul Human; Jeffrey A Hubbell; Neil Davies
The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides.
Biomaterials 2005;26(2):167-74.
2004: D Seliktar; Andreas H Zisch; Matthias P Lutolf; J L Wrana; Jeffrey A Hubbell
MMP-2 sensitive, VEGF-bearing bioactive hydrogels for promotion of vascular healing.
Journal of biomedical materials research. Part A 2004;68(4):704-16.
2004: Yongdoo Park; Matthias P Lutolf; Jeffrey A Hubbell; Ernst B Hunziker; Marcy Wong
Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair.
Tissue engineering 2004;10(3-4):515-22.
2003: Andreas H Zisch; Matthias P Lutolf; Martin Ehrbar; George Raeber; Simone C Rizzi; Neil Davies; Hugo Schmökel; Deon Bezuidenhout; Valentin Djonov; Peter Zilla; Jeffrey A Hubbell
Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(15):2260-2.
2003: Andreas H Zisch; Matthias P Lutolf; Jeffrey A Hubbell
Biopolymeric delivery matrices for angiogenic growth factors.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2003;12(6):295-310.
2003: Matthias P Lutolf; Jeffrey A Hubbell
Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition.
Biomacromolecules 2003;4(3):713-22.
2003: Matthias P Lutolf; Franz Weber; Hugo G Schmoekel; Jason C Schense; Thomas Kohler; Ralph Müller; Jeffrey A Hubbell
Repair of bone defects using synthetic mimetics of collagenous extracellular matrices.
Nature biotechnology 2003;21(5):513-8.
2003: Matthias P Lutolf; Janelle L Lauer-Fields; Hugo G Schmoekel; A T Metters; Franz Weber; Gregg Fields; Jeffrey A Hubbell
Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5413-8.
2002: Nicola Tirelli; Matthias P Lutolf; Alessandro Napoli; Jeffrey A Hubbell
Poly(ethylene glycol) block copolymers.
Journal of biotechnology 2002;90(1):3-15.
2001: Matthias P Lutolf; Nicola Tirelli; S Cerritelli; L Cavalli; Jeffrey A Hubbell
Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids.
Bioconjugate chemistry 2001;12(6):1051-6.
2001: D L Elbert; A B Pratt; Matthias P Lutolf; S Halstenberg; Jeffrey A Hubbell
Protein delivery from materials formed by self-selective conjugate addition reactions.
Journal of controlled release : official journal of the Controlled Release Society 2001;76(1-2):11-25.