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Stefan Lyer

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Christina Janko; Sarah von Löhneysen; Stefan Lyer; Luis E Munoz; Christine Schorn; Rainer Tietze; Ricardo Chaurio; Stephan Dürr; Martin Herrmann; Christoph Alexiou
Magnetic drug targeting reduces the chemotherapeutic burden on circulating leukocytes.
Stephan Dürr; Martin Herrmann; Christina Janko; Stefan Lyer; Jenny Mann; Eveline Schreiber; Rainer Tietze; Christoph Alexiou
Real-time cell analysis of human cancer cell lines after chemotherapy with functionalized magnetic nanoparticles.
Rainer Tietze; Stephan Dürr; Stefan Lyer; Christoph Alexiou
Nanoparticles for cancer therapy using magnetic forces.

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All Publications

2013: Christina Janko; Sarah von Löhneysen; Stefan Lyer; Luis E Munoz; Christine Schorn; Rainer Tietze; Ricardo Chaurio; Stephan Dürr; Martin Herrmann; Christoph Alexiou
Magnetic drug targeting reduces the chemotherapeutic burden on circulating leukocytes.
International journal of molecular sciences 2013;14(4):7341-55.
2012: Stephan Dürr; Martin Herrmann; Christina Janko; Stefan Lyer; Jenny Mann; Eveline Schreiber; Rainer Tietze; Christoph Alexiou
Real-time cell analysis of human cancer cell lines after chemotherapy with functionalized magnetic nanoparticles.
Anticancer research 2012;32(5):1983-9.
2012: Rainer Tietze; Stephan Dürr; Stefan Lyer; Christoph Alexiou
Nanoparticles for cancer therapy using magnetic forces.
Nanomedicine (London, England) 2012;7(3):447-57.
2011: Rainer Tietze; Helene Rahn; Stefan Lyer; Eveline Schreiber; Jenny Mann; Stefan Odenbach; Christoph Alexiou
Visualization of superparamagnetic nanoparticles in vascular tissue using XμCT and histology.
Histochemistry and cell biology 2011;135(2):153-8.
2010: Christoph Alexiou; R Tietze; E Schreiber; Stefan Lyer
[Nanomedicine : Magnetic nanoparticles for drug delivery and hyperthermia - new chances for cancer therapy].
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 2010;53(8):839-45.
2010: Stefan Lyer; Rainer Tietze; Roland Jurgons; Tobias Struffert; Tobias Engelhorn; Eveline Schreiber; Arnd Dörfler; Christoph Alexiou
Visualisation of tumour regression after local chemotherapy with magnetic nanoparticles - a pilot study.
Anticancer research 2010;30(5):1553-7.
2010: Rainer Tietze; Eveline Schreiber; Stefan Lyer; Christoph Alexiou
Mitoxantrone loaded superparamagnetic nanoparticles for drug targeting: a versatile and sensitive method for quantification of drug enrichment in rabbit tissues using HPLC-UV.
Journal of biomedicine & biotechnology 2010;2010():597304.
2010: Andrea Reinartz; Josef Ehling; Susanne Franz; Verena Simon; Ignacio G Bravo; Claudia Tessmer; Hanswalter Zentgraf; Stefan Lyer; Ursula Schneider; Jan Köster; Kerstin Raupach; Elke Kämmerer; Christina Klaus; Jens J W Tischendorf; Jürgen Kopitz; Angel Alonso; Nikolaus Gassler
Small intestinal mucosa expression of putative chaperone fls485.
BMC gastroenterology 2010;10():27.
2010: Sandrine Tchatchou; Angela Riedel; Stefan Lyer; Julia Schmutzhard; Olga Strobel-Freidekind; Sabine Gronert-Sum; Carola Mietag; Mauro D'Amato; Bettina Schlehe; Kari Hemminki; Christian Sutter; Nina Ditsch; Anneke Blackburn; Linda Zhai Hill; D Joseph Jerry; Peter Bugert; Bernhard H F Weber; Dieter Niederacher; Norbert Arnold; Raymonda Varon-Mateeva; Barbara Wappenschmidt; Rita K Schmutzler; Christoph Engel; Alfons Meindl; Claus R Bartram; Jan Mollenhauer; Barbara Burwinkel
Identification of a DMBT1 polymorphism associated with increased breast cancer risk and decreased promoter activity.
Human mutation 2010;31(1):60-6.
2009: Caroline End; Floris J Bikker; Marcus Renner; Gaby Bergmann; Stefan Lyer; Stephanie Blaich; Melanie Hudler; Burkhard Helmke; Nikolaus Gassler; Frank Autschbach; Antoon J M Ligtenberg; Axel Benner; Uffe Holmskov; Peter Schirmacher; Arie V Nieuw Amerongen; Philip Rosenstiel; Christian Sina; Andre Franke; Mathias Hafner; Petra Kioschis; Stefan Schreiber; Annemarie Poustka; Jan Mollenhauer
DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands.
European journal of immunology 2009;39(3):833-42.
2007: Marcus Renner; Gaby Bergmann; Inge Krebs; Caroline End; Stefan Lyer; Frank Hilberg; Burkhard Helmke; Nikolaus Gassler; Frank Autschbach; Floris J Bikker; Olga Strobel-Freidekind; Sabine Gronert-Sum; Axel Benner; Stephanie Blaich; Rainer Wittig; Melanie Hudler; Antoon J M Ligtenberg; Jens Madsen; Uffe Holmskov; Vito Annese; Anna Latiano; Peter Schirmacher; Arie V Nieuw Amerongen; Mauro D'Amato; Petra Kioschis; Mathias Hafner; Annemarie Poustka; Jan Mollenhauer
DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease.
Gastroenterology 2007;133(5):1499-509.
2007: Philip Rosenstiel; Christian Sina; Caroline End; Marcus Renner; Stefan Lyer; Andreas Till; Stephan Hellmig; Susanna Nikolaus; Ulrich R Fölsch; Burkhard Helmke; Frank Autschbach; Peter Schirmacher; Petra Kioschis; Mathias Hafner; Annemarie Poustka; Jan Mollenhauer; Stefan Schreiber
Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):8203-11.
2006: Nikolaus Gassler; Dieter Newrzella; Christine Böhm; Stefan Lyer; L Li; Oliver Sorgenfrei; L van Laer; Bernd Sido; J Mollenhauer; Annemarie Poustka; Peter Schirmacher; N Gretz
Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine.
Gut 2006;55(8):1084-9.
2006: Bianca Haase; Sean Humphray; Stefan Lyer; Marcus Renner; Annemarie Poustka; Jan Mollenhauer; Tosso Leeb
Molecular characterization of the porcine deleted in malignant brain tumors 1 gene (DMBT1).
Gene 2006;376(2):184-91.
2005: Caroline End; Stefan Lyer; Marcus Renner; Cordula Stahl; Jutta Ditzer; Andreas Holloschi; Hella-Monika Kuhn; Heiko T Flammann; Annemarie Poustka; Mathias Hafner; Jan Mollenhauer; Petra Kioschis
Generation of a vector system facilitating cloning of DMBT1 variants and recombinant expression of functional full-length DMBT1.
Protein expression and purification 2005;41(2):275-86.
2005: Rainer Wittig; Rüdiger Salowsky; Stephanie Blaich; Stefan Lyer; Juehn S Maa; Odilo Müller; Jan Mollenhauer; Annemarie Poustka
Multiplex reverse transcription-polymerase chain reaction combined with on-chip electrophoresis as a rapid screening tool for candidate gene sets.
Electrophoresis 2005;26(9):1687-91.
2004: Burkhard Helmke; Jan Mollenhauer; Christel Herold-Mende; Axel Benner; Marianne Thome; Nikolaus Gassler; Wolfgang Wahl; Stefan Lyer; Annemarie Poustka; Herwart F Otto; Martin Deichmann
BRAF mutations distinguish anorectal from cutaneous melanoma at the molecular level.
Gastroenterology 2004;127(6):1815-20.
2004: Floris J Bikker; Antoon J M Ligtenberg; Caroline End; Marcus Renner; Stephanie Blaich; Stefan Lyer; Rainer Wittig; Wim van't Hof; Enno C I Veerman; Kamran Nazmi; Jolanda M A de Blieck-Hogervorst; Petra Kioschis; Arie V Nieuw Amerongen; Annemarie Poustka; Jan Mollenhauer
Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains.
The Journal of biological chemistry 2004;279(46):47699-703.
2004: Jan Mollenhauer; Burkhard Helmke; Daniel Medina; Gaby Bergmann; Nikolaus Gassler; Hanna Müller; Stefan Lyer; Laura Diedrichs; Marcus Renner; Rainer Wittig; Stephanie Blaich; Ute Hamann; Jens Madsen; Uffe Holmskov; Floris J Bikker; Antoon J M Ligtenberg; Anette Carlén; Jan Olsson; Herwart F Otto; Bert O'Malley; Annemarie Poustka
Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis.
Genes, chromosomes & cancer 2004;39(3):185-94.
2004: Nikolaus Gassler; Jürgen Kopitz; Arman Tehrani; Birgit Ottenwälder; Martina Schnölzer; Jürgen Kartenbeck; Stefan Lyer; Frank Autschbach; Annemarie Poustka; Herwart F Otto; Jan Mollenhauer
Expression of acyl-CoA synthetase 5 reflects the state of villus architecture in human small intestine.
The Journal of pathology 2004;202(2):188-96.
2002: Jan Mollenhauer; Hanna Müller; Gaby Kollender; Stefan Lyer; Laura Diedrichs; Burkhard Helmke; Uffe Holmskov; Toon Ligtenberg; Stephan Herbertz; Inge Krebs; Jens Madsen; Floris J Bikker; Liane Schmitt; Stefan Wiemann; Wolfram Scheurlen; Herwart F Otto; Andreas von Deimling; Annemarie Poustka
The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer.
Genes, chromosomes & cancer 2002;35(3):242-55.
2002: Jan Mollenhauer; Burkhard Helmke; Hanna Müller; Gaby Kollender; Stefan Lyer; Laura Diedrichs; Uffe Holmskov; Toon Ligtenberg; Stephan Herbertz; Inge Krebs; Stefan Wiemann; Jens Madsen; Floris J Bikker; Liane Schmitt; Herwart F Otto; Annemarie Poustka
Sequential changes of the DMBT1 expression and location in normal lung tissue and lung carcinomas.
Genes, chromosomes & cancer 2002;35(2):164-9.