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Lee Lynd

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TOP 3
Jilai Zhou; D Aaron Argyros; Yu Deng; Daniel G Olson; Johannes P van Dijken; Walter M van Gulik; Lee R Lynd
Atypical Glycolysis in Clostridium thermocellum.
Xiongjun Shao; Lee R Lynd
Kinetic modeling of xylan hydrolysis in co- and countercurrent liquid hot water flow-through pretreatments.
Daniel G Olson; Richard J Giannone; Robert L Hettich; Lee R Lynd
Role of the CipA scaffoldin protein in cellulose solubilization, as determined by targeted gene deletion and complementation in Clostridium thermocellum.

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All Publications

2013: Jilai Zhou; D Aaron Argyros; Yu Deng; Daniel G Olson; Johannes P van Dijken; Walter M van Gulik; Lee R Lynd
Atypical Glycolysis in Clostridium thermocellum.
Applied and environmental microbiology 2013;79(9):3000-8.
2013: Xiongjun Shao; Lee R Lynd
Kinetic modeling of xylan hydrolysis in co- and countercurrent liquid hot water flow-through pretreatments.
Bioresource technology 2013;130():117-24.
2013: Daniel G Olson; Richard J Giannone; Robert L Hettich; Lee R Lynd
Role of the CipA scaffoldin protein in cellulose solubilization, as determined by targeted gene deletion and complementation in Clostridium thermocellum.
Journal of bacteriology 2013;195(4):733-9.
2013: Devin H Currie; Adam M Guss; Christopher D Herring; David A Hogsett; Daniel G Olson; Lee R Lynd
Functional heterologous expression of an engineered full length CipA from Clostridium thermocellum in Thermoanaerobacterium saccharolyticum.
Biotechnology for biofuels 2013;6(1):32.
2013: Yu Deng; Christopher D Herring; A Joe Shaw; Daniel G Olson; Jilai Zhou; Lee R Lynd
Redirecting carbon flux through exogenous pyruvate kinase to achieve high ethanol yields in Clostridium thermocellum.
Metabolic engineering 2013;15():151-8.
2012: Kara K Podkaminer; Heather L Trajano; Adam M Guss; David A Hogsett; Lee R Lynd
Characterization of xylan utilization and discovery of a new endoxylanase in Thermoanaerobacterium saccharolyticum through targeted gene deletions.
Applied and environmental microbiology 2012;78(23):8441-7.
2012: Evert K Holwerda; Kyle D Hirst; Lee R Lynd
A defined growth medium with very low background carbon for culturing Clostridium thermocellum.
Journal of industrial microbiology & biotechnology 2012;39(6):943-7.
2012: Daniel G Olson; A Joe Shaw; John E McBride; Lee R Lynd
Recent progress in consolidated bioprocessing.
Current opinion in biotechnology 2012;23(3):396-405.
2012: Elizabeth B Mearls; Javier A Izquierdo; Lee R Lynd
Formation and characterization of non-growth states in Clostridium thermocellum: spores and L-forms.
BMC microbiology 2012;12():180.
2012: Veronique Archambault-Leger; Xiongjun Shao; Lee R Lynd
Integrated analysis of hydrothermal flow through pretreatment.
Biotechnology for biofuels 2012;5(1):49.
2012: Kara K Podkaminer; Christopher D Herring; David A Hogsett; William R Kenealy; Lee R Lynd
Ethanol and anaerobic conditions reversibly inhibit commercial cellulase activity in thermophilic simultaneous saccharification and fermentation (tSSF).
Biotechnology for biofuels 2012;5(1):43.
2012: Daniel G Olson; Lee R Lynd
Transformation of Clostridium thermocellum by electroporation.
Methods in enzymology 2012;510():317-30.
2012: Daniel G Olson; Lee R Lynd
Computational design and characterization of a temperature-sensitive plasmid replicon for gram positive thermophiles.
Journal of biological engineering 2012;6(1):5.
2012: Adam M Guss; Nicky C Caiazza; Daniel G Olson; Lee R Lynd
Dcm methylation is detrimental to plasmid transformation in Clostridium thermocellum.
Biotechnology for biofuels 2012;5(1):30.
2012: Lucas D Ellis; David Hogsett; Evert K Holwerda; Steve Rogers; Xiongjun Shao; Phil Thorne; Timothy Tschaplinski; Lee R Lynd
Closing the carbon balance for fermentation by Clostridium thermocellum (ATCC 27405).
Bioresource technology 2012;103(1):293-9.
2011: Xiongjun Shao; Mingjun Zhu; Steven D Brown; Adam M Guss; Jonathan R Mielenz; Babu Raman; Lee R Lynd
Mutant selection and phenotypic and genetic characterization of ethanol-tolerant strains of Clostridium thermocellum.
Applied microbiology and biotechnology 2011;92(3):641-52.
2011: Steven D Brown; Adam M Guss; Tatiana V Karpinets; Martin Keller; Dawn M Klingeman; Miriam L Land; Ashwini Bhandiwad; Jonathan R Mielenz; Jerry M Parks; Babu Raman; Miguel Rodriguez; Xiongjun Shao; Jeremy C Smith; Nikolai Smolin; Shihui Yang; Lee R Lynd
Mutant alcohol dehydrogenase leads to improved ethanol tolerance in Clostridium thermocellum.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(33):13752-7.
2011: Kara K Podkaminer; Xiongjun Shao; David A Hogsett; Lee R Lynd
Enzyme inactivation by ethanol and development of a kinetic model for thermophilic simultaneous saccharification and fermentation at 50 °C with Thermoanaerobacterium saccharolyticum ALK2.
Biotechnology and bioengineering 2011;108(6):1268-78.
2011: Josebus M van Zyl; Estrelita Janse van Rensburg; Willem H van Zyl; Thomas M Harms; Lee R Lynd
A kinetic model for simultaneous saccharification and fermentation of Avicel with Saccharomyces cerevisiae.
Biotechnology and bioengineering 2011;108(4):924-33.
2011: M V Sizova; J A Izquierdo; N S Panikov; Lee R Lynd
Cellulose- and xylan-degrading thermophilic anaerobic bacteria from biocompost.
Applied and environmental microbiology 2011;77(7):2282-91.
2010: Lee R Lynd; Carlos Henrique de Brito Cruz
Make way for ethanol.
Science (New York, N.Y.) 2010;330(6008):1176.
2010: Jiayi Zhang; Lee R Lynd
Ethanol production from paper sludge by simultaneous saccharification and co-fermentation using recombinant xylose-fermenting microorganisms.
Biotechnology and bioengineering 2010;107(2):235-44.
2010: A Joe Shaw; David A Hogsett; Lee R Lynd
Natural competence in Thermoanaerobacter and Thermoanaerobacterium species.
Applied and environmental microbiology 2010;76(14):4713-9.
2010: Javier A Izquierdo; Maria V Sizova; Lee R Lynd
Diversity of bacteria and glycosyl hydrolase family 48 genes in cellulolytic consortia enriched from thermophilic biocompost.
Applied and environmental microbiology 2010;76(11):3545-53.
2010: Xiongjun Shao; Lee R Lynd; André Bakker; Richard LaRoche; Charles Wyman
Reactor scale up for biological conversion of cellulosic biomass to ethanol.
Bioprocess and biosystems engineering 2010;33(4):485-93.
2009: Jiayi Zhang; Xiongjun Shao; Lee R Lynd
Simultaneous saccharification and co-fermentation of paper sludge to ethanol by Saccharomyces cerevisiae RWB222. Part II: investigation of discrepancies between predicted and observed performance at high solids concentration.
Biotechnology and bioengineering 2009;104(5):932-8.
2009: Jiayi Zhang; Xiongjun Shao; Oliver V Townsend; Lee R Lynd
Simultaneous saccharification and co-fermentation of paper sludge to ethanol by Saccharomyces cerevisiae RWB222--Part I: kinetic modeling and parameters.
Biotechnology and bioengineering 2009;104(5):920-31.
2009: A Joe Shaw; David A Hogsett; Lee R Lynd
Identification of the [FeFe]-hydrogenase responsible for hydrogen generation in Thermoanaerobacterium saccharolyticum and demonstration of increased ethanol yield via hydrogenase knockout.
Journal of bacteriology 2009;191(20):6457-64.
2009: Xiongjun Shao; Lee R Lynd; Charles E Wyman; André Bakker
Kinetic modeling of cellulosic biomass to ethanol via simultaneous saccharification and fermentation: Part I. Accommodation of intermittent feeding and analysis of staged reactors.
Biotechnology and bioengineering 2009;102(1):59-65.
2009: Xiongjun Shao; Lee R Lynd; Charles E Wyman
Kinetic modeling of cellulosic biomass to ethanol via simultaneous saccharification and fermentation: Part II. Experimental validation using waste paper sludge and anticipation of CFD analysis.
Biotechnology and bioengineering 2009;102(1):66-72.
2008: A Joe Shaw; Kara K Podkaminer; Brenda Osborne; John S Bardsley; Stephen R Rogers; Philip G Thorne; David A Hogsett; Lee R Lynd
Metabolic engineering of a thermophilic bacterium to produce ethanol at high yield.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):13769-74.
2008: Lee R Lynd; Mark S Laser; David Bransby; Bruce E Dale; Brian Davison; Richard Hamilton; Michael Himmel; Martin Keller; James D McMillan; John Sheehan; Charles E Wyman
How biotech can transform biofuels.
Nature biotechnology 2008;26(2):169-72.
2007: Yi-Heng Percival Zhang; Shi-You Ding; Jonathan R Mielenz; Jing-Biao Cui; Richard T Elander; Mark Laser; Michael E Himmel; James R McMillan; Lee R Lynd
Fractionating recalcitrant lignocellulose at modest reaction conditions.
Biotechnology and bioengineering 2007;97(2):214-23.
2007: Willem H van Zyl; Lee R Lynd; Riaan Den Haan; John E McBride
Consolidated bioprocessing for bioethanol production using Saccharomyces cerevisiae.
Advances in biochemical engineering/biotechnology 2007;108():205-35.
2007: Riaan Den Haan; Shaunita H Rose; Lee R Lynd; Willem H van Zyl
Hydrolysis and fermentation of amorphous cellulose by recombinant Saccharomyces cerevisiae.
Metabolic engineering 2007;9(1):87-94.
2007: Zhiliang Fan; Lee R Lynd
Conversion of paper sludge to ethanol, II: process design and economic analysis.
Bioprocess and biosystems engineering 2007;30(1):35-45.
2007: Zhiliang Fan; Lee R Lynd
Conversion of paper sludge to ethanol. I: impact of feeding frequency and mixing energy characterization.
Bioprocess and biosystems engineering 2007;30(1):27-34.
2006: Yanpin Lu; Yi-Heng Percival Zhang; Lee R Lynd
Enzyme-microbe synergy during cellulose hydrolysis by Clostridium thermocellum.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16165-9.
2006: Y-H Percival Zhang; Lee R Lynd
A functionally based model for hydrolysis of cellulose by fungal cellulase.
Biotechnology and bioengineering 2006;94(5):888-98.
2006: Y-H P Zhang; Lee R Lynd
Biosynthesis of radiolabeled cellodextrins by the Clostridium thermocellum cellobiose and cellodextrin phosphorylases for measurement of intracellular sugars.
Applied microbiology and biotechnology 2006;70(1):123-9.
2006: Y-H Percival Zhang; Jingbiao Cui; Lee R Lynd; Lana R Kuang
A transition from cellulose swelling to cellulose dissolution by o-phosphoric acid: evidence from enzymatic hydrolysis and supramolecular structure.
Biomacromolecules 2006;7(2):644-8.
2005: Michael V Tyurin; Charles R Sullivan; Lee R Lynd
Role of spontaneous current oscillations during high-efficiency electrotransformation of thermophilic anaerobes.
Applied and environmental microbiology 2005;71(12):8069-76.
2005: Zhiliang Fan; John E McBride; Willem H van Zyl; Lee R Lynd
Theoretical analysis of selection-based strain improvement for microorganisms with growth dependent upon extracytoplasmic enzymes.
Biotechnology and bioengineering 2005;92(1):35-44.
2005: Lee R Lynd; Willem H van Zyl; John E McBride; Mark Laser
Consolidated bioprocessing of cellulosic biomass: an update.
Current opinion in biotechnology 2005;16(5):577-83.
2005: Yi-Heng Percival Zhang; Lee R Lynd
Cellulose utilization by Clostridium thermocellum: bioenergetics and hydrolysis product assimilation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(20):7321-5.
2005: Y-H Percival Zhang; Lee R Lynd
Determination of the number-average degree of polymerization of cellodextrins and cellulose with application to enzymatic hydrolysis.
Biomacromolecules 2005;6(3):1510-5.
2005: Yi-Heng Percival Zhang; Lee R Lynd
Regulation of cellulase synthesis in batch and continuous cultures of Clostridium thermocellum.
Journal of bacteriology 2005;187(1):99-106.
2004: Yi-Heng Percival Zhang; Lee R Lynd
Toward an aggregated understanding of enzymatic hydrolysis of cellulose: noncomplexed cellulase systems.
Biotechnology and bioengineering 2004;88(7):797-824.
2004: Melek Ozkan; Ebru I Yilmaz; Lee R Lynd; Gülay Ozcengiz
Cloning and expression of the Clostridium thermocellum L-lactate dehydrogenase gene in Escherichia coli and enzyme characterization.
Canadian journal of microbiology 2004;50(10):845-51.
2004: Brenda Osborne; Mary Lou Guerinot; Lee R Lynd
Cloning of L-lactate dehydrogenase and elimination of lactic acid production via gene knockout in Thermoanaerobacterium saccharolyticum JW/SL-YS485.
Applied microbiology and biotechnology 2004;65(5):600-5.
2004: Yi-Heng Percival Zhang; Lee R Lynd
Kinetics and relative importance of phosphorolytic and hydrolytic cleavage of cellodextrins and cellobiose in cell extracts of Clostridium thermocellum.
Applied and environmental microbiology 2004;70(3):1563-9.
2004: Michael V Tyurin; Brenda Osborne; Lee R Lynd
Electrotransformation of Clostridium thermocellum.
Applied and environmental microbiology 2004;70(2):883-90.
2004: Thomas W Jeffries; Lee R Lynd
Introduction to microbial catalysis and engineering.
Applied biochemistry and biotechnology 2004;113-116():323-4.
2003: Zhiliang Fan; Colin South; Kimberly Lyford; Jeffery Munsie; Peter van Walsum; Lee R Lynd
Conversion of paper sludge to ethanol in a semicontinuous solids-fed reactor.
Bioprocess and biosystems engineering 2003;26(2):93-101.
2003: Yi-Heng Percival Zhang; Lee R Lynd
Cellodextrin preparation by mixed-acid hydrolysis and chromatographic separation.
Analytical biochemistry 2003;322(2):225-32.
2003: Yiheng Zhang; Lee R Lynd
Quantification of cell and cellulase mass concentrations during anaerobic cellulose fermentation: development of an enzyme-linked immunosorbent assay-based method with application to Clostridium thermocellum batch cultures.
Analytical chemistry 2003;75(2):219-27.
2002: Lee R Lynd; Paul J Weimer; Willem H van Zyl; Isak S Pretorius
Microbial cellulose utilization: fundamentals and biotechnology.
Microbiology and molecular biology reviews : MMBR 2002;66(3):506-77, table of contents.
2002: Lee R Lynd; Yiheng Zhang
Quantitative determination of cellulase concentration as distinct from cell concentration in studies of microbial cellulose utilization: analytical framework and methodological approach.
Biotechnology and bioengineering 2002;77(4):467-75.
2002: Mark Laser; D Schulman; S G Allen; J Lichwa; M J Antal; Lee R Lynd
A comparison of liquid hot water and steam pretreatments of sugar cane bagasse for bioconversion to ethanol.
Bioresource technology 2002;81(1):33-44.
2001: M Ozkan; Brenda Osborne; Y Zhang; D M Stevenson; J Beane; E A White; Mary Lou Guerinot; Lee R Lynd
Characterization of 13 newly isolated strains of anaerobic, cellulolytic, thermophilic bacteria.
Journal of industrial microbiology & biotechnology 2001;27(5):275-80.
2001: Lee R Lynd; S Baskaran; S Casten
Salt accumulation resulting from base added for pH control, and not ethanol, limits growth of Thermoanaerobacteriumthermosaccharolyticum HG-8 at elevated feed xylose concentrations in continuous culture.
Biotechnology progress 2001;17(1):118-25.
1998: G P van Walsum; Lee R Lynd
Allocation of ATP to synthesis of cells and hydrolytic enzymes in cellulolytic fermentative microorganisms: bioenergetics, kinetics, and bioprocessing.
Biotechnology and bioengineering 1998;58(2-3):316-20.
1998: H Garant; Lee R Lynd
Applicability of competitive and noncompetitive kinetics to the reductive dechlorination of chlorinated ethenes.
Biotechnology and bioengineering 1998;57(6):751-5.
1989: Lee R Lynd; H E Grethlein; R H Wolkin
Fermentation of Cellulosic Substrates in Batch and Continuous Culture by Clostridium thermocellum.
Applied and environmental microbiology 1989;55(12):3131-9.