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Rolf Barth

Research Profile

Procedures

Boron Neutron Capture Therapy

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Frederick K Racke; Michael Weldon; Weilian Yang; Maureen Baird; Rolf F Barth; Nilendu Gupta; Tianyao Huo; Heather Rutledge
Unique in vitro and in vivo thrombopoietic activities of ingenol 3,20 dibenzoate, a Ca(++)-independent protein kinase C isoform agonist.
Tianyao Huo; Rumiana Koynova; Robin J Nakkula; Boris Tenchov; Weilian Yang; Lawrence Agius; Rolf F Barth; Teni Boulikas; Abhik Ray Chaudhury; Hélène Elleaume; Robert J Lee
Preparation, biodistribution and neurotoxicity of liposomal cisplatin following convection enhanced delivery in normal and F98 glioma bearing rats.
Rolf F Barth; Peter J Binns; Otto K Harling; Itsuro Kato; WS Kiger; Kent J Riley; Minoru Suzuki; M Graça H Vicente; Franz M Wagner; Teruhito Aihara; Shinji Kawabata
Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer.

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2012: Frederick K Racke; Michael Weldon; Weilian Yang; Maureen Baird; Rolf F Barth; Nilendu Gupta; Tianyao Huo; Heather Rutledge
Unique in vitro and in vivo thrombopoietic activities of ingenol 3,20 dibenzoate, a Ca(++)-independent protein kinase C isoform agonist.
PloS one 2012;7(12):e51059.
2012: Tianyao Huo; Rumiana Koynova; Robin J Nakkula; Boris Tenchov; Weilian Yang; Lawrence Agius; Rolf F Barth; Teni Boulikas; Abhik Ray Chaudhury; Hélène Elleaume; Robert J Lee
Preparation, biodistribution and neurotoxicity of liposomal cisplatin following convection enhanced delivery in normal and F98 glioma bearing rats.
PloS one 2012;7(11):e48752.
2012: Rolf F Barth; Peter J Binns; Otto K Harling; Itsuro Kato; WS Kiger; Kent J Riley; Minoru Suzuki; M Graça H Vicente; Franz M Wagner; Teruhito Aihara; Shinji Kawabata
Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer.
Radiation oncology (London, England) 2012;7():146.
2011: Rolf F Barth; Peter J Binns; John C Grecula; Nilendu Gupta; Tianyao Huo; Kent J Riley; Julia Rousseau; Weilian Yang; Hélène Elleaume
Comparison of intracerebral delivery of carboplatin and photon irradiation with an optimized regimen for boron neutron capture therapy of the F98 rat glioma.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2011;69(12):1813-6.
2011: Weilian Yang; Tianyao Huo; Rolf F Barth; Nilendu Gupta; Michael Weldon; John C Grecula; Brian D Ross; Benjamin A Hoff; Ting-Chao Chou; Julia Rousseau; Hélène Elleaume
Convection enhanced delivery of carboplatin in combination with radiotherapy for the treatment of brain tumors.
Journal of neuro-oncology 2011;101(3):379-90.
2010: Chenguang Zhou; Bo Yu; Xiaojuan Yang; Tianyao Huo; L James Lee; Rolf F Barth; Robert J Lee
Lipid-coated nano-calcium-phosphate (LNCP) for gene delivery.
International journal of pharmaceutics 2010;392(1-2):201-8.
2009: Weilian Yang; Rolf F Barth; Gong Wu; Tianyao Huo; Werner Tjarks; Michael J Ciesielski; Robert A Fenstermaker; Brian D Ross; Carol J Wikstrand; Kent J Riley; Peter J Binns
Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors.
Journal of neuro-oncology 2009;95(3):355-65.
2009: Rolf F Barth; Balveen Kaur
Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas.
Journal of neuro-oncology 2009;94(3):299-312.
2009: Weilian Yang; Rolf F Barth; Gong Wu; Werner Tjarks; Peter J Binns; Kent Riley
Boron neutron capture therapy of EGFR or EGFRvIII positive gliomas using either boronated monoclonal antibodies or epidermal growth factor as molecular targeting agents.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2009;67(7-8 Suppl):S328-31.
2009: Rolf F Barth
Boron neutron capture therapy at the crossroads: challenges and opportunities.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2009;67(7-8 Suppl):S3-6.
2009: Gregory A Christoforidis; Ming Yang; Marinos S Kontzialis; Douglas G Larson; Amir M Abduljalil; Michelle Basso; Weilian Yang; Abhik Ray-Chaudhury; Johannes T Heverhagen; Michael V Knopp; Rolf F Barth
High resolution ultra high field magnetic resonance imaging of glioma microvascularity and hypoxia using ultra-small particles of iron oxide.
Investigative radiology 2009;44(7):375-83.
2008: Rolf F Barth; Weilian Yang; Gong Wu; Michele Swindall; Youngjoo Byun; Sureshbabu Narayanasamy; Werner Tjarks; Kevin Tordoff; Melvin L Moeschberger; Staffan Eriksson; Peter J Binns; Kent J Riley
Thymidine kinase 1 as a molecular target for boron neutron capture therapy of brain tumors.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(45):17493-7.
2008: Weilian Yang; Gong Wu; Rolf F Barth; Michele R Swindall; Achintya K Bandyopadhyaya; Werner Tjarks; Kevin Tordoff; Melvin L Moeschberger; Thomas J Sferra; Peter J Binns; Kent J Riley; Michael J Ciesielski; Robert A Fenstermaker; Carol J Wikstrand
Molecular targeting and treatment of composite EGFR and EGFRvIII-positive gliomas using boronated monoclonal antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(3):883-91.
2008: Subhash Chandra; Werner Tjarks; Daniel R Lorey; Rolf F Barth
Quantitative subcellular imaging of boron compounds in individual mitotic and interphase human glioblastoma cells with imaging secondary ion mass spectrometry (SIMS).
Journal of microscopy 2008;229(Pt 1):92-103.
2007: Werner Tjarks; Rohit Tiwari; Youngjoo Byun; Sureshbabu Narayanasamy; Rolf F Barth
Carboranyl thymidine analogues for neutron capture therapy.
Chemical communications (Cambridge, England) 2007;(47):4978-91.
2007: Gong Wu; Weilian Yang; Rolf F Barth; Shinji Kawabata; Michele Swindall; Achintya K Bandyopadhyaya; Werner Tjarks; Behrooz Khorsandi; Thomas E Blue; Amy K Ferketich; Ming Yang; Gregory A Christoforidis; Thomas J Sferra; Peter J Binns; Kent J Riley; Michael J Ciesielski; Robert A Fenstermaker
Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(4):1260-8.
2007: Rolf F Barth; Heikki Joensuu
Boron neutron capture therapy for the treatment of glioblastomas and extracranial tumours: as effective, more effective or less effective than photon irradiation?
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;82(2):119-22.
2007: Xiaogang Pan; Gong Wu; Weiliang Yang; Rolf F Barth; Werner Tjarks; Robert J Lee
Synthesis of cetuximab-immunoliposomes via a cholesterol-based membrane anchor for targeting of EGFR.
Bioconjugate chemistry 2007;18(1):101-8.
2006: Youngjoo Byun; B T S Thirumamagal; Weilian Yang; Staffan Eriksson; Rolf F Barth; Werner Tjarks
Preparation and biological evaluation of 10B-enriched 3-[5-{2-(2,3-dihydroxyprop-1-yl)-o-carboran-1-yl}pentan-1-yl]thymidine (N5-2OH), a new boron delivery agent for boron neutron capture therapy of brain tumors.
Journal of medicinal chemistry 2006;49(18):5513-23.
2006: B T S Thirumamagal; Xiaobin B Zhao; Achintya K Bandyopadhyaya; Sureshbabu Naranyanasamy; Jayaseharan Johnsamuel; Rohit Tiwari; Danold W Golightly; Vimalkumar Patel; Brian T Jehning; Marina V Backer; Rolf F Barth; Robert J Lee; Joseph M Backer; Werner Tjarks
Receptor-targeted liposomal delivery of boron-containing cholesterol mimics for boron neutron capture therapy (BNCT).
Bioconjugate chemistry 2006;17(5):1141-50.
2006: Weilian Yang; Rolf F Barth; Gong Wu; Shinji Kawabata; Thomas J Sferra; Achintya K Bandyopadhyaya; Werner Tjarks; Amy K Ferketich; Melvin L Moeschberger; Peter J Binns; Kent J Riley; Jeffrey A Coderre; Michael J Ciesielski; Robert A Fenstermaker; Carol J Wikstrand
Molecular targeting and treatment of EGFRvIII-positive gliomas using boronated monoclonal antibody L8A4.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(12):3792-802.
2006: Gong Wu; Rolf F Barth; Weilian Yang; Robert J Lee; Werner Tjarks; Marina V Backer; Joseph M Backer
Boron containing macromolecules and nanovehicles as delivery agents for neutron capture therapy.
Anti-cancer agents in medicinal chemistry 2006;6(2):167-84.
2006: Youngjoo Byun; Sureshbabu Narayanasamy; Jayaseharan Johnsamuel; Achintya K Bandyopadhyaya; Rohit Tiwari; Ashraf S Al-Madhoun; Rolf F Barth; Staffan Eriksson; Werner Tjarks
3-Carboranyl thymidine analogues (3CTAs) and other boronated nucleosides for boron neutron capture therapy.
Anti-cancer agents in medicinal chemistry 2006;6(2):127-44.
2006: B T S Thirumamagal; Jayaseharan Johnsamuel; Guirec Y Cosquer; Youngjoo Byun; Junhua Yan; Sureshbabu Narayanasamy; Werner Tjarks; Rolf F Barth; Ashraf S Al-Madhoun; Staffan Eriksson
Boronated thymidine analogues for boron neutron capture therapy.
Nucleosides, nucleotides & nucleic acids 2006;25(8):861-6.
2006: Gong Wu; Rolf F Barth; Weilian Yang; Shinji Kawabata; Liwen Zhang; Kari B Green-Church
Targeted delivery of methotrexate to epidermal growth factor receptor-positive brain tumors by means of cetuximab (IMC-C225) dendrimer bioconjugates.
Molecular cancer therapeutics 2006;5(1):52-9.
2005: Marina V Backer; Timur I Gaynutdinov; Vimal Patel; Achintya K Bandyopadhyaya; B T S Thirumamagal; Werner Tjarks; Rolf F Barth; Kevin P Claffey; Joseph M Backer
Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature.
Molecular cancer therapeutics 2005;4(9):1423-9.
2005: Rolf F Barth; Jeffrey A Coderre; M Graça H Vicente; Thomas E Blue
Boron neutron capture therapy of cancer: current status and future prospects.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(11):3987-4002.
2005: Youngjoo Byun; Junhua Yan; Ashraf S Al-Madhoun; Jayaseharan Johnsamuel; Weilian Yang; Rolf F Barth; Staffan Eriksson; Werner Tjarks
Synthesis and biological evaluation of neutral and zwitterionic 3-carboranyl thymidine analogues for boron neutron capture therapy.
Journal of medicinal chemistry 2005;48(4):1188-98.
2005: Michael J Ciesielski; A Latif Kazim; Rolf F Barth; Robert A Fenstermaker
Cellular antitumor immune response to a branched lysine multiple antigenic peptide containing epitopes of a common tumor-specific antigen in a rat glioma model.
Cancer immunology, immunotherapy : CII 2005;54(2):107-19.
2005: Weilian Yang; Rolf F Barth; Gong Wu; Michael J Ciesielski; Robert A Fenstermaker; Bradford Moffat; Brian D Ross; Carol J Wikstrand
Development of a syngeneic rat brain tumor model expressing EGFRvIII and its use for molecular targeting studies with monoclonal antibody L8A4.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(1):341-50.
2004: Youngjoo Byun; Junhua Yan; Ashraf S Al-Madhoun; Jayaseharan Johnsamuel; Weilian Yang; Rolf F Barth; Staffan Eriksson; Werner Tjarks
The synthesis and biochemical evaluation of thymidine analogues substituted with nido carborane at the N-3 position.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2004;61(5):1125-30.
2004: Weilian Yang; Rolf F Barth; Gong Wu; Achintya K Bandyopadhyaya; B T S Thirumamagal; Werner Tjarks; Peter J Binns; Kent Riley; Hemant Patel; Jeffrey A Coderre; Michael J Ciesielski; Robert A Fenstermaker
Boronated epidermal growth factor as a delivery agent for neutron capture therapy of EGF receptor positive gliomas.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2004;61(5):981-5.
2004: Rolf F Barth; Gong Wu; Weilian Yang; Peter J Binns; Kent J Riley; Hemant Patel; Jeffrey A Coderre; Werner Tjarks; Achintya K Bandyopadhyaya; B T S Thirumamagal; Michael J Ciesielski; Robert A Fenstermaker
Neutron capture therapy of epidermal growth factor (+) gliomas using boronated cetuximab (IMC-C225) as a delivery agent.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2004;61(5):899-903.
2004: Rolf F Barth; Weilian Yang; Ashraf S Al-Madhoun; Jayaseharan Johnsamuel; Youngjoo Byun; Subhash Chandra; Duane R Smith; Werner Tjarks; Staffan Eriksson
Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors.
Cancer research 2004;64(17):6287-95.
2004: Ashraf S Al-Madhoun; Jayaseharan Johnsamuel; Rolf F Barth; Werner Tjarks; Staffan Eriksson
Evaluation of human thymidine kinase 1 substrates as new candidates for boron neutron capture therapy.
Cancer research 2004;64(17):6280-6.
2004: Gong Wu; Rolf F Barth; Weilian Yang; Madhumita Chatterjee; Werner Tjarks; Michael J Ciesielski; Robert A Fenstermaker
Site-specific conjugation of boron-containing dendrimers to anti-EGF receptor monoclonal antibody cetuximab (IMC-C225) and its evaluation as a potential delivery agent for neutron capture therapy.
Bioconjugate chemistry 2004;15(1):185-94.
2004: Rolf F Barth; John C Grecula; Weilan Yang; Joan H. Rotaru; Marta M Nawrocky; Nilendu Gupta; Brent J Albertson; Amy K Ferketich; Melvin L Moeschberger; Jeffrey A Coderre; Einar K Rofstad
Combination of boron neutron capture therapy and external beam radiotherapy for brain tumors.
International journal of radiation oncology, biology, physics 2004;58(1):267-77.
2003: Stacy M Stephenson; Weilian Yang; Phillip J Stevens; Werner Tjarks; Rolf F Barth; Robert J Lee
Folate receptor-targeted liposomes as possible delivery vehicles for boron neutron capture therapy.
Anticancer research 2003;23(4):3341-5.
2003: Christopher R Gibson; Alfred E Staubus; Rolf F Barth; Weilian Yang; Amy K Ferketich; Melvin M Moeschberger
Pharmacokinetics of sodium borocaptate: a critical assessment of dosing paradigms for boron neutron capture therapy.
Journal of neuro-oncology 2003;62(1-2):157-69.
2003: Rolf F Barth; Weilian Yang; Jeffrey A Coderre
Rat brain tumor models to assess the efficacy of boron neutron capture therapy: a critical evaluation.
Journal of neuro-oncology 2003;62(1-2):61-74.
2003: Rolf F Barth
A critical assessment of boron neutron capture therapy: an overview.
Journal of neuro-oncology 2003;62(1-2):1-5.
2003: Sameek Roychowdhury; Ruoqi Peng; Robert A Baiocchi; Darshna Bhatt; Srinivas Vourganti; John C Grecula; Nilendu Gupta; Charles F Eisenbeis; Gerard J Nuovo; Weilian Yang; Petra Schmalbrock; Amy K Ferketich; Melvin L Moeschberger; Pierluigi Porcu; Rolf F Barth; Michael A Caligiuri
Experimental treatment of Epstein-Barr virus-associated primary central nervous system lymphoma.
Cancer research 2003;63(5):965-71.
2003: Supriya Shukla; Gong Wu; Madhumita Chatterjee; Weilian Yang; Masaru Sekido; Lamine A Diop; Rainer Müller; Jennifer J Sudimack; Robert J Lee; Rolf F Barth; Werner Tjarks
Synthesis and biological evaluation of folate receptor-targeted boronated PAMAM dendrimers as potential agents for neutron capture therapy.
Bioconjugate chemistry 2003;14(1):158-67.
2002: Weilian Yang; Rolf F Barth; Dianne M Adams; Michael J Ciesielski; Robert A Fenstermaker; Supriya Shukla; Werner Tjarks; Michael A Caligiuri
Convection-enhanced delivery of boronated epidermal growth factor for molecular targeting of EGF receptor-positive gliomas.
Cancer research 2002;62(22):6552-8.
2002: Jennifer J Sudimack; Dianne Adams; Joan H. Rotaru; Supriya Shukla; Junhua Yan; Masaru Sekido; Rolf F Barth; Werner Tjarks; Robert J Lee
Folate receptor-mediated liposomal delivery of a lipophilic boron agent to tumor cells in vitro for neutron capture therapy.
Pharmaceutical research 2002;19(10):1502-8.
2002: Rolf F Barth; Weilian Yang; Dianne M Adams; Joan H. Rotaru; Supriya Shukla; Masaru Sekido; Werner Tjarks; Robert A Fenstermaker; Michael J Ciesielski; Marta M Nawrocky; Jeffrey A Coderre
Molecular targeting of the epidermal growth factor receptor for neutron capture therapy of gliomas.
Cancer research 2002;62(11):3159-66.
2002: Christopher R Gibson; Alfred E Staubus; Rolf F Barth; Weilian Yang; Nanette M Kleinholz; R Benjamin Jones; Kari B Green-Church; Werner Tjarks; Albert H Soloway
Electrospray ionization mass spectrometry coupled to reversed-phase ion-pair high-performance liquid chromatography for quantitation of sodium borocaptate and application to pharmacokinetic analysis.
Analytical chemistry 2002;74(10):2394-9.
2002: Xing Q Pan; Huaqing Wang; Supriya Shukla; Masaru Sekido; Dianne M Adams; Werner Tjarks; Rolf F Barth; Robert J Lee
Boron-containing folate receptor-targeted liposomes as potential delivery agents for neutron capture therapy.
Bioconjugate chemistry 2002;13(3):435-42.
2002: Rolf F Barth; Weilian Yang; raymond bartus; Joan H. Rotaru; Amy K Ferketich; Melvin L Moeschberger; Marta M Nawrocky; Jeffrey A Coderre; Einar K Rofstad
Neutron capture therapy of intracerebral melanoma: enhanced survival and cure after blood-brain barrier opening to improve delivery of boronophenylalanine.
International journal of radiation oncology, biology, physics 2002;52(3):858-68.
2002: Sara Novick; Michael Quastel; Stephanie Marcus; David Chipman; Gad Shani; Rolf F Barth; Albert H Soloway
Linkage of boronated polylysine to glycoside moieties of polyclonal antibody; boronated antibodies as potential delivery agents for neutron capture therapy.
Nuclear medicine and biology 2002;29(2):159-67.
2001: Christopher R Gibson; Alfred E Staubus; Rolf F Barth; Weilian Yang; Nanette M Kleinholz; R Benjamin Jones; Kari B Green-Church; Werner Tjarks; Albert H Soloway
Boron neutron capture therapy of brain tumors: investigation of urinary metabolites and oxidation products of sodium borocaptate by electrospray ionization mass spectrometry.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(12):1588-98.
2001: Duane R Smith; Subhash Chandra; Rolf F Barth; Weilian Yang; DD Joel; Jeffrey A Coderre
Quantitative imaging and microlocalization of boron-10 in brain tumors and infiltrating tumor cells by SIMS ion microscopy: relevance to neutron capture therapy.
Cancer research 2001;61(22):8179-87.
2001: Weilian Yang; Rolf F Barth; R Leveille; Dianne M Adams; Michael J Ciesielski; Robert A Fenstermaker; J Capala
Evaluation of systemically administered radiolabeled epidermal growth factor as a brain tumor targeting agent.
Journal of neuro-oncology 2001;55(1):19-28.
2001: Werner Tjarks; Rolf F Barth; Joan H. Rotaru; Dianne M Adams; Weilian Yang; Roman G Kultyshev; J Forrester; B A Barnum; Albert H Soloway; Sheldon G Shore
In vivo evaluation of phosphorous-containing derivatives of dodecahydro-closo-dodecaborate for boron neutron capture therapy of gliomas and sarcomas.
Anticancer research 2001;21(2A):841-6.
2000: Dianne M Adams; Weihua Ji; Rolf F Barth; Werner Tjarks
Comparative in vitro evaluation of dequalinium B, a new boron carrier for neutron capture therapy (NCT).
Anticancer research 2000;20(5B):3395-402.
2000: JH Goodman; Weilian Yang; Rolf F Barth; Z Gao; Carl P Boesel; Alfred E Staubus; Nilendu Gupta; Reinhard A Gahbauer; Dianne M Adams; Christopher R Gibson; Amy K Ferketich; Melvin L Moeschberger; Albert H Soloway; D E Carpenter; Brent J Albertson; W F Bauer; M Z Zhang; C C Wang
Boron neutron capture therapy of brain tumors: biodistribution, pharmacokinetics, and radiation dosimetry sodium borocaptate in patients with gliomas.
Neurosurgery 2000;47(3):608-21; discussion 621-2.
2000: Weilian Yang; Rolf F Barth; Joan H. Rotaru; Carl P Boesel; D A Wilkie; J C Bresnahan; Maria Hadjiconstantinou; Virginia M Goettl; DD Joel; Marta M Nawrocky
Boron neutron capture therapy of brain tumors: functional and neuropathologic effects of blood-brain barrier disruption and intracarotid injection of sodium borocaptate and boronophenylalanine.
Journal of neuro-oncology 2000;48(3):179-90.
2000: Weilian Yang; Rolf F Barth; raymond bartus; Joan H. Rotaru; Melvin L Moeschberger; Amy K Ferketich; Marta M Nawrocky; Jeffrey A Coderre; JH Goodman
Improved survival after boron neutron capture therapy of brain tumors by Cereport-mediated blood-brain barrier modulation to enhance delivery of boronophenylalanine.
Neurosurgery 2000;47(1):189-97; discussion 197-8.
2000: Rolf F Barth; Weilian Yang; Joan H. Rotaru; Melvin L Moeschberger; Carl P Boesel; Albert H Soloway; DD Joel; Marta M Nawrocky; K Ono; JH Goodman
Boron neutron capture therapy of brain tumors: enhanced survival and cure following blood-brain barrier disruption and intracarotid injection of sodium borocaptate and boronophenylalanine.
International journal of radiation oncology, biology, physics 2000;47(1):209-18.
1999: Jin-Cong Zhuo; J Cai; Albert H Soloway; Rolf F Barth; Dianne M Adams; Weihua Ji; Werner Tjarks
Synthesis and biological evaluation of boron-containing polyamines as potential agents for neutron capture therapy of brain tumors.
Journal of medicinal chemistry 1999;42(7):1282-92.
1999: Rolf F Barth; Albert H Soloway; JH Goodman; Reinhard A Gahbauer; Nilendu Gupta; Thomas E Blue; Weilian Yang; Werner Tjarks
Boron neutron capture therapy of brain tumors: an emerging therapeutic modality.
Neurosurgery 1999;44(3):433-50; discussion 450-1.
1999: Rolf F Barth; Weilian Yang; raymond bartus; Melvin L Moeschberger; JH Goodman
Enhanced delivery of boronophenylalanine for neutron capture therapy of brain tumors using the bradykinin analog Cereport (Receptor-Mediated Permeabilizer-7).
Neurosurgery 1999;44(2):351-9; discussion 359-60.
1998: Rolf F Barth
Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas.
Journal of neuro-oncology 1998;36(1):91-102.
1997: J Cai; Albert H Soloway; Rolf F Barth; Dianne M Adams; J R Hariharan; I M Wyzlic; K Radcliffe
Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: synthesis and biological evaluation.
Journal of medicinal chemistry 1997;40(24):3887-96.
1997: Weilian Yang; Rolf F Barth; Dianne M Adams; Albert H Soloway
Intratumoral delivery of boronated epidermal growth factor for neutron capture therapy of brain tumors.
Cancer research 1997;57(19):4333-9.
1997: J Capala; Rolf F Barth; M Q Bailey; Robert A Fenstermaker; Milan Marek; BA Rhodes
Radiolabeling of epidermal growth factor with 99mTc and in vivo localization following intracerebral injection into normal and glioma-bearing rats.
Bioconjugate chemistry 1997;8(3):289-95.
1997: Weilian Yang; Rolf F Barth; Joan H. Rotaru; Melvin L Moeschberger; DD Joel; Marta M Nawrocky; JH Goodman
Enhanced survival of glioma bearing rats following boron neutron capture therapy with blood-brain barrier disruption and intracarotid injection of boronophenylalanine.
Journal of neuro-oncology 1997;33(1-2):59-70.
1997: Albert H Soloway; Rolf F Barth; Reinhard A Gahbauer; Thomas E Blue; JH Goodman
The rationale and requirements for the development of boron neutron capture therapy of brain tumors.
Journal of neuro-oncology 1997;33(1-2):9-18.
1997: Rolf F Barth; Albert H Soloway
Boron neutron capture therapy of brain tumors--current status and future prospects.
Journal of neuro-oncology 1997;33(1-2):3-7.
1997: Rolf F Barth; Weilian Yang; Joan H. Rotaru; Melvin L Moeschberger; DD Joel; Marta M Nawrocky; JH Goodman; Albert H Soloway
Boron neutron capture therapy of brain tumors: enhanced survival following intracarotid injection of either sodium borocaptate or boronophenylalanine with or without blood-brain barrier disruption.
Cancer research 1997;57(6):1129-36.
1997: Weilian Yang; Rolf F Barth; Joan H. Rotaru; Melvin L Moeschberger; DD Joel; Marta M Nawrocky; JH Goodman; Albert H Soloway
Boron neutron capture therapy of brain tumors: enhanced survival following intracarotid injection of sodium borocaptate with or without blood-brain barrier disruption.
International journal of radiation oncology, biology, physics 1997;37(3):663-72.
1996: L Liu; Rolf F Barth; Dianne M Adams; Albert H Soloway; R A Reisfeld
Critical evaluation of bispecific antibodies as targeting agents for boron neutron capture therapy of brain tumors.
Anticancer research 1996;16(5A):2581-7.
1996: Weilian Yang; Rolf F Barth; D E Carpenter; Melvin L Moeschberger; JH Goodman
Enhanced delivery of boronophenylalanine for neutron capture therapy by means of intracarotid injection and blood-brain barrier disruption.
Neurosurgery 1996;38(5):985-92.
1996: Rolf F Barth; Albert H Soloway; R M Brugger
Boron neutron capture therapy of brain tumors: past history, current status, and future potential.
Cancer investigation 1996;14(6):534-50.
1996: J Capala; Rolf F Barth; Moise Bendayan; M Lauzon; Dianne M Adams; Albert H Soloway; R A Fenstermaker; J Carlsson
Boronated epidermal growth factor as a potential targeting agent for boron neutron capture therapy of brain tumors.
Bioconjugate chemistry 1996;7(1):7-15.
1996: L Liu; Rolf F Barth; Werner Tjarks; Albert H Soloway; A K Anisuzzaman
In vitro and in vivo evaluation of carboranyl uridines as boron delivery agents for neutron capture therapy.
Anticancer research 1996;16(1):113-20.
1995: L Liu; Rolf F Barth; Dianne M Adams; Albert H Soloway; R A Reisfeld
Bispecific antibodies as targeting agents for boron neutron capture therapy of brain tumors.
Journal of hematotherapy 1995;4(5):477-83.
1995: J H Yong; Rolf F Barth; Joan H. Rotaru; I M Wyzlic; Albert H Soloway
Evaluation of in vitro cytotoxicity of carboranyl amino acids, their chemical precursors and nido carboranyl amino acids for boron neutron capture therapy.
Anticancer research 1995;15(5B):2039-43.
1995: J H Yong; Rolf F Barth; I M Wyzlic; Albert H Soloway; Joan H. Rotaru
In vitro and in vivo evaluation of o-carboranylalanine as a potential boron delivery agent for neutron capture therapy.
Anticancer research 1995;15(5B):2033-8.
1995: K Nishihara; Rolf F Barth; N Wilkie; James C Lang; Y Oda; H Kikuchi; M P Everson; M T Lotze
Increased in vitro and in vivo tumoricidal activity of a macrophage cell line genetically engineered to express IFN-gamma, IL-4, IL-6, or TNF-alpha.
Cancer gene therapy 1995;2(2):113-24.
1994: I M Wyzlic; Werner Tjarks; Albert H Soloway; A K Anisuzzaman; F G Rong; Rolf F Barth
Strategies for the design and synthesis of boronated nucleic acid and protein components as potential delivery agents for neutron capture therapy.
International journal of radiation oncology, biology, physics 1994;28(5):1203-13.
1994: K Z Matalka; Rolf F Barth; M Q Bailey; David A Wilkie; A Koestner; J W Hopewell
Radiation effects of boron neutron capture therapy on brain, skin, and eye of rats.
International journal of radiation oncology, biology, physics 1994;28(5):1089-97.
1994: Rolf F Barth; K Z Matalka; M Q Bailey; A E Staubus; Albert H Soloway; Melvin L Moeschberger; J A Coderre; E K Rofstad
A nude rat model for neutron capture therapy of human intracerebral melanoma.
International journal of radiation oncology, biology, physics 1994;28(5):1079-88.
1994: Rolf F Barth; Albert H Soloway
Boron neutron capture therapy of primary and metastatic brain tumors.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1994;21(2-3):139-54.
1994: K Z Matalka; Rolf F Barth; A E Staubus; Melvin L Moeschberger; J A Coderre
Neutron capture therapy of a rat glioma using boronophenylalanine as a capture agent.
Radiation research 1994;137(1):44-51.
1994: Rolf F Barth; Dianne M Adams; Albert H Soloway; F Alam; M V Darby
Boronated starburst dendrimer-monoclonal antibody immunoconjugates: evaluation as a potential delivery system for neutron capture therapy.
Bioconjugate chemistry 1994;5(1):58-66.
1993: K Z Matalka; M Q Bailey; Rolf F Barth; A E Staubus; Albert H Soloway; Melvin L Moeschberger; J A Coderre; E K Rofstad
Boron neutron capture therapy of intracerebral melanoma using boronophenylalanine as a capture agent.
Cancer research 1993;53(14):3308-13.
1992: Rolf F Barth; Albert H Soloway; R G Fairchild; R M Brugger
Boron neutron capture therapy for cancer. Realities and prospects.
Cancer 1992;70(12):2995-3007.
1992: O A Oredipe; Rolf F Barth; Joan H. Rotaru; Z Steplewski
Lack of effect of recombinant human interferon-alpha 2b on expression of 17-1A antigen on human colon cancer cells.
Hybridoma 1992;11(5):607-15.
1992: O A Oredipe; Rolf F Barth; Chandradhar Dwivedi; T E Webb
Dietary glucarate-mediated inhibition of initiation of diethylnitrosamine-induced hepatocarcinogenesis.
Toxicology 1992;74(2-3):209-22.
1992: Werner Tjarks; A K Anisuzzaman; L Liu; Albert H Soloway; Rolf F Barth; Douglas J Perkins; Dianne M Adams
Synthesis and in vitro evaluation of boronated uridine and glucose derivatives for boron neutron capture therapy.
Journal of medicinal chemistry 1992;35(9):1628-33.
1992: J J Tzeng; Rolf F Barth; Charles G Orosz
Quantitation of glioma-reactive cytolytic T lymphocyte precursors by means of limiting dilution analysis.
Journal of immunological methods 1992;146(2):177-84.
1991: J J Tzeng; Rolf F Barth; Charles G Orosz; S M James
Phenotype and functional activity of tumor-infiltrating lymphocytes isolated from immunogenic and nonimmunogenic rat brain tumors.
Cancer research 1991;51(9):2373-8.
1991: Rolf F Barth; Dianne M Adams; Albert H Soloway; E B Mechetner; F Alam; A K Anisuzzaman
Determination of boron in tissues and cells using direct-current plasma atomic emission spectroscopy.
Analytical chemistry 1991;63(9):890-3.
1990: Rolf F Barth; Albert H Soloway; R G Fairchild
Boron neutron capture therapy for cancer.
Scientific American 1990;263(4):100-3, 106-7.
1990: O A Oredipe; Rolf F Barth; Joan H. Rotaru; George Hinkle; Z Steplewski
Alterations in monoclonal antibody affinity and antigenic receptor site expression on mycoplasma-infected human colorectal cancer cells.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1990;194(4):301-7.
1990: JH Goodman; J M McGregor; N R Clendenon; Reinhard A Gahbauer; Rolf F Barth; Albert H Soloway; R G Fairchild
Inhibition of tumor growth in a glioma model treated with boron neutron capture therapy.
Neurosurgery 1990;27(3):383-8.
1990: J J Tzeng; Rolf F Barth; N R Clendenon; W A Gordon
Adoptive immunotherapy of a rat glioma using lymphokine-activated killer cells and interleukin 2.
Cancer research 1990;50(14):4338-43.
1990: J J Tzeng; Rolf F Barth
Sensitivity of B16 melanoma sublines to lymphokine-activated killer cells as determined by 51Cr-release and clonogenic assays.
Journal of immunological methods 1990;128(2):257-66.
1990: J J Tzeng; Rolf F Barth; C W Johnson; Dianne M Adams
Distinct and non-cross-reactive epitopes are recognized on B16 melanoma by LAK cells and anti-B16 monoclonal antibodies.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1990;193(4):285-92.
1990: Rolf F Barth; Albert H Soloway; R G Fairchild
Boron neutron capture therapy of cancer.
Cancer research 1990;50(4):1061-70.
1990: N R Clendenon; Rolf F Barth; W A Gordon; JH Goodman; F Alam; A E Staubus; C P Boesel; Allan J Yates; Melvin L Moeschberger; R G Fairchild
Boron neutron capture therapy of a rat glioma.
Neurosurgery 1990;26(1):47-55.
1990: Albert H Soloway; F Alam; Rolf F Barth; A K Anisuzzaman; B V Bapat
Tumor targeting agents for neutron capture therapy.
Basic life sciences 1990;54():37-47.
1989: O A Oredipe; D E Schumm; F Mercurio; S Larroya; Rolf F Barth; T E Webb
A carcinogenesis- and tumorigenesis-associated rat fetal protein: an immuno-histochemical and immuno-biochemical study utilizing a new monoclonal antibody, MOFP.
Carcinogenesis 1989;10(12):2175-81.
1989: F Alam; Albert H Soloway; Rolf F Barth; N Mafune; Dianne M Adams; W H Knoth
Boron neutron capture therapy: linkage of a boronated macromolecule to monoclonal antibodies directed against tumor-associated antigens.
Journal of medicinal chemistry 1989;32(10):2326-30.
1989: O A Oredipe; Rolf F Barth; Chandradhar Dwivedi; T E Webb
Chemopreventative activity of dietary glucarate on azoxymethane-induced altered hepatic foci in rats.
Research communications in chemical pathology and pharmacology 1989;65(3):345-59.
1989: Chandradhar Dwivedi; O A Oredipe; Rolf F Barth; A A Downie; T E Webb
Effects of the experimental chemopreventative agent, glucarate, on intestinal carcinogenesis in rats.
Carcinogenesis 1989;10(8):1539-41.
1989: JH Goodman; J M McGregor; N R Clendenon; Reinhard A Gahbauer; Rolf F Barth; Albert H Soloway; R G Fairchild
Ultrastructural microvascular response to boron neutron capture therapy in an experimental model.
Neurosurgery 1989;24(5):701-8.
1989: Moise Bendayan; Rolf F Barth; D Gingras; Irene Londoño; P T Robinson; F Alam; Dianne M Adams; L Mattiazzi
Electron spectroscopic imaging for high-resolution immunocytochemistry: use of boronated protein A.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1989;37(5):573-80.
1989: N R Clendenon; Rolf F Barth; JH Goodman; A E Staubus; W A Gordon; Melvin L Moeschberger; F Alam; Albert H Soloway; R G Fairchild; D N Slatkin
Enhanced survival in a rat glioma model following BNCT.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1989;165(2-3):222-5.
1989: Rolf F Barth; N Mafune; F Alam; Dianne M Adams; Albert H Soloway; G E Makroglou; O A Oredipe; Thomas E Blue; Z Steplewski
Conjugation, purification and characterization of boronated monoclonal antibodies for use in neutron capture therapy.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1989;165(2-3):142-5.
1989: F Alam; B V Bapat; Albert H Soloway; Rolf F Barth; N Mafune; Dianne M Adams
Boronated compounds for neutron capture therapy.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1989;165(2-3):121-3.
1989: Albert H Soloway; F Alam; Rolf F Barth; B V Bapat
Boron chemistry and target cell affinity.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 1989;165(2-3):118-20.
1989: Rolf F Barth; Albert H Soloway; F Alam; N R Clendenon; Thomas E Blue; N Mafune; JH Goodman; W Gordon; B Bapat; Dianne M Adams
Pre-clinical studies on boron neutron capture therapy.
Basic life sciences 1989;50():95-105.
1989: JH Goodman; J M McGregor; N R Clendenon; W A Gordon; Allan J Yates; Reinhard A Gahbauer; Rolf F Barth; R G Fairchild
Delayed effects of neutron irradiation on central nervous system microvasculature in the rat.
Basic life sciences 1989;50():87-93.
1989: F Alam; Albert H Soloway; B V Bapat; Rolf F Barth; Dianne M Adams
Boron compounds for neutron capture therapy.
Basic life sciences 1989;50():107-11.
1988: O A Oredipe; Rolf F Barth; S E Tuttle; Dianne M Adams; I Sautins; D M Bucci; C M Mojzisik; George Hinkle; S Jewell; Z Steplewski
Limits of sensitivity for the radioimmunodetection of colon cancer by means of a hand held gamma probe.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1988;15(6):595-603.
1987: O A Oredipe; Rolf F Barth; M Hanausek-Walaszek; I Sautins; Z Walaszek; T E Webb
Effects of calcium glucarate on the promotion of diethylnitrosamine-initiated altered hepatic foci in rats.
Cancer letters 1987;38(1-2):95-9.
1987: C W Johnson; Rolf F Barth; D Adams; B Holman; J E Price; I Sautins
Phenotypic diversity of murine B16 melanoma detected by anti-B16 monoclonal antibodies.
Cancer research 1987;47(4):1111-7.
1987: F Alam; Albert H Soloway; Rolf F Barth
Boronation of antibodies with mercaptoundecahydro-closo-dodecaborate(2-) anion for potential use in boron neutron capture therapy.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1987;38(7):503-6.
1986: Edward W Martin; S E Tuttle; M Rousseau; C M Mojzisik; P J O'Dwyer; George Hinkle; E A Miller; R A Goodwin; O A Oredipe; Rolf F Barth
Radioimmunoguided surgery: intraoperative use of monoclonal antibody 17-1A in colorectal cancer.
Hybridoma 1986;5 Suppl 1():S97-108.
1986: Rolf F Barth; F Alam; Albert H Soloway; Dianne M Adams; Z Steplewski
Boronated monoclonal antibody 17-1A for potential neutron capture therapy of colorectal cancer.
Hybridoma 1986;5 Suppl 1():S43-50.
1985: C W Johnson; Wei-Zen Wei; Rolf F Barth; S E Tuttle; C A Andrews
Monoclonal antibodies directed against preneoplastic and neoplastic murine mammary lesions.
Cancer research 1985;45(8):3774-81.
1985: F Alam; Albert H Soloway; J E McGuire; Rolf F Barth; W E Carey; D Adams
Dicesium N-succinimidyl 3-(undecahydro-closo-dodecaboranyldithio)propionate, a novel heterobifunctional boronating agent.
Journal of medicinal chemistry 1985;28(4):522-5.
1984: J E Price; Rolf F Barth; C W Johnson; A E Staubus
Injection of cells and monoclonal antibodies into mice: comparison of tail vein and retroorbital routes.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1984;177(2):347-53.
1982: Rolf F Barth; C W Johnson; Wei-Zen Wei; W E Carey; Albert H Soloway; J McGuire
Neutron capture using boronated monoclonal antibody directed against tumor-associated antigens.
Cancer detection and prevention 1982;5(3):315-23.