FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Stefan Barth

Research Profile

Chemicals & Drugs

Disorders

Hodgkin's Disease

Living Beings

Anatomy

Procedures

Immunotherapy

Co-author Network

Publications

TOP 3
Christiane Puettmann; Severin Schmies; Rainer Fischer; Sven Hagen; Katharina Kolberg; Joerg Naehring; Stefan Barth
A monoclonal antibody for the detection of SNAP/CLIP-tagged proteins.
Alessa Pardo; Michael Stöcker; Theo Thepen; Rainer Fischer; Florian Kampmeier; Georg Melmer; Stefan Barth
In vivo imaging of immunotoxin treatment using Katushka-transfected A-431 cells in a murine xenograft tumour model.
Dmitrij Hristodorov; Michael Huhn; Radoslav Mladenov; Stefan Barth; Theo Thepen
Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Stefan Barth (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Christiane Puettmann; Severin Schmies; Rainer Fischer; Sven Hagen; Katharina Kolberg; Joerg Naehring; Stefan Barth
A monoclonal antibody for the detection of SNAP/CLIP-tagged proteins.
Immunology letters 2013;150(1-2):69-74.
2012: Alessa Pardo; Michael Stöcker; Theo Thepen; Rainer Fischer; Florian Kampmeier; Georg Melmer; Stefan Barth
In vivo imaging of immunotoxin treatment using Katushka-transfected A-431 cells in a murine xenograft tumour model.
Cancer immunology, immunotherapy : CII 2012;61(10):1617-26.
2012: Dmitrij Hristodorov; Michael Huhn; Radoslav Mladenov; Stefan Barth; Theo Thepen
Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases.
Toxins 2012;4(9):676-94.
2012: Eva-Maria Siepert; Mehmet Kemal Tur; Stefan Barth; Heinrich Delbrück; Esther Gartz; Jochen Büchs
Short-chain fluorescent tryptophan tags for on-line detection of functional recombinant proteins.
BMC biotechnology 2012;12():65.
2011: Lotfi Abou-Elkacem; Stefan Barth; Felix Gremse; Robert M Hoffman; Fabian Kiessling; Wiltrud Lederle
Comparison of μCT, MRI and optical reflectance imaging for assessing the growth of GFP/RFP-expressing tumors.
Anticancer research 2011;31(9):2907-13.
2011: Mehmet K Tur; Tim H Brümmendorf; Michael Huhn; Edgar Jost; Theo Thepen; Stefan Barth
In vivo efficacy of the recombinant anti-CD64 immunotoxin H22(scFv)-ETA' in a human acute myeloid leukemia xenograft tumor model.
International journal of cancer. Journal international du cancer 2011;129(5):1277-82.
2011: Tobias Recker; Anne Schmitt; Stefan Barth; Daniel Haamann; Doris Klee; Andrea Küster; Gerhard Müller-Newen
Directed covalent immobilization of fluorescently labeled cytokines.
Bioconjugate chemistry 2011;22(6):1210-20.
2011: Stefan Kraus; Michael Kleines; Jörg Albers; Lars Blohm; Gundula Piechotta; Christiane Püttmann; Stefan Barth; JM Nähring; Eric Nebling
Quantitative measurement of human anti-HCV Core immunoglobulins on an electrical biochip platform.
Biosensors & bioelectronics 2011;26(5):1895-901.
2010: Florian Kampmeier; Judith Niesen; Alexander Koers; Markus Ribbert; Andreas Brecht; Rainer Fischer; Fabian Kiessling; Stefan Barth; Theo Thepen
Rapid optical imaging of EGF receptor expression with a single-chain antibody SNAP-tag fusion protein.
European journal of nuclear medicine and molecular imaging 2010;37(10):1926-34.
2010: T Ribbert; Theo Thepen; Mehmet K Tur; Rainer Fischer; Michael Huhn; Stefan Barth
Recombinant, ETA'-based CD64 immunotoxins: improved efficacy by increased valency, both in vitro and in vivo in a chronic cutaneous inflammation model in human CD64 transgenic mice.
The British journal of dermatology 2010;163(2):279-86.
2010: Gabriele Thumann; Michael Stöcker; C Maltusch; A K Salz; Stefan Barth; P Walter; S Johnen
High efficiency non-viral transfection of retinal and iris pigment epithelial cells with pigment epithelium-derived factor.
Gene therapy 2010;17(2):181-9.
2009: Katharina Ranft; Theo Thepen; Rainer Fischer; Stefan Barth; Michael Stöcker
Recombinant bispecific single chain antibody fragments induce Fc gamma-receptor-mediated elimination of CD30+ lymphoma cells.
Cancer letters 2009;282(2):187-94.
2009: Mehmet K Tur; Inga Neef; Edgar Jost; Oliver Galm; Gernot Jäger; Michael Stöcker; Markus Ribbert; Rainhardt Osieka; Uwe Klinge; Stefan Barth
Targeted restoration of down-regulated DAPK2 tumor suppressor activity induces apoptosis in Hodgkin lymphoma cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(5):431-41.
2009: Florian Kampmeier; Markus Ribbert; Thomas Nachreiner; Sofia Dembski; Florent Beaufils; Andreas Brecht; Stefan Barth
Site-specific, covalent labeling of recombinant antibody fragments via fusion to an engineered version of 6-O-alkylguanine DNA alkyltransferase.
Bioconjugate chemistry 2009;20(5):1010-5.
2009: T Thepen; Michael Huhn; G Melmer; Mehmet K Tur; Stefan Barth
Fcgamma receptor 1 (CD64), a target beyond cancer.
Current pharmaceutical design 2009;15(23):2712-8.
2009: Mehmet K Tur; Inga Neef; Gernot Jäger; Andreas Teubner; Michael Stöcker; Georg Melmer; Stefan Barth
Immunokinases, a novel class of immunotherapeutics for targeted cancer therapy.
Current pharmaceutical design 2009;15(23):2693-9.
2009: Hannah Jörissen; Nuran Bektas; Edgar Dahl; Arndt Hartmann; Anette ten Haaf; Stefano Di Fiore; Hans Kiefer; Andreas Thess; Stefan Barth; Torsten Klockenbring
Production and characterisation of monoclonal antibodies against RAI3 and its expression in human breast cancer.
BMC cancer 2009;9():200.
2009: Ulrich Wullner; Inga Neef; Mehmet K Tur; Stefan Barth
Targeted delivery of short interfering RNAs--strategies for in vivo delivery.
Recent patents on anti-cancer drug discovery 2009;4(1):1-8.
2008: Bettina Stahnke; Theo Thepen; Michael Stöcker; Reinhard Rosinke; Edgar Jost; Rainer Fischer; Mehmet K Tur; Stefan Barth
Granzyme B-H22(scFv), a human immunotoxin targeting CD64 in acute myeloid leukemia of monocytic subtypes.
Molecular cancer therapeutics 2008;7(9):2924-32.
2008: Christian Hetzel; Christopher Bachran; Rainer Fischer; Hendrik Fuchs; Stefan Barth; Michael Stöcker
Small cleavable adapters enhance the specific cytotoxicity of a humanized immunotoxin directed against CD64-positive cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(4):370-6.
2008: Thomas Nachreiner; Florian Kampmeier; Theo Thepen; Rainer Fischer; Stefan Barth; Michael Stöcker
Depletion of autoreactive B-lymphocytes by a recombinant myelin oligodendrocyte glycoprotein-based immunotoxin.
Journal of neuroimmunology 2008;195(1-2):28-35.
2006: Daniel Wicklein; Michael Stöcker; T Klockenbring; Michael Huhn; M Wodrich; Helmut Haas; Wolf-Meinhard Becker; Stefan Barth; Arnd Petersen
In contrast to specific B cells, human basophils are unaffected by the toxic activity of an allergen toxin due to lack of internalization of immunoglobulin E-bound allergen.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2006;36(4):531-42.
2005: Antje Paetz; Markus Sack; Theo Thepen; Mehmet K Tur; Daniela Bruell; Ricarda Finnern; Rainer Fischer; Stefan Barth
Recombinant soluble human Fcgamma receptor I with picomolar affinity for immunoglobulin G.
Biochemical and biophysical research communications 2005;338(4):1811-7.
2005: Michael Stöcker; Torsten Klockenbring; Michael Huhn; Thomas Nachreiner; Daniel Wicklein; Arnd Petersen; Ralf Bauer; Roland Goerlich; Rainer Fischer; Stefan Barth
Antigen-specific targeting and elimination of EBV-transformed B cells by allergen toxins.
The Journal of allergy and clinical immunology 2005;116(4):910-5.
2005: Daniela Bruell; Christiane J Bruns; Maksim Yezhelyev; Michael Huhn; Jürgen Müller; Ivan Ischenko; Rainer Fischer; Ricarda Finnern; Karl-Walter Jauch; Stefan Barth
Recombinant anti-EGFR immunotoxin 425(scFv)-ETA' demonstrates anti-tumor activity against disseminated human pancreatic cancer in nude mice.
International journal of molecular medicine 2005;15(2):305-13.
2005: Michael B Kuepper; Michael Huhn; Holger Spiegel; Julian K-C Ma; Stefan Barth; Rainer Fischer; Ricarda Finnern
Generation of human antibody fragments against Streptococcus mutans using a phage display chain shuffling approach.
BMC biotechnology 2005;5():4.
2004: Alexander Klimka; Mehmet K Tur; Michael Huhn; Uwe Bierfreund; Estela Terrada; Rainer Fischer; Ricarda Finnern; Stefan Barth
Measurement of antibody-membrane interactions by surface plasmon resonance.
International journal of molecular medicine 2004;14(4):765-8.
2004: Achim Rothe; Alexander Klimka; Mehmet K Tur; T Pfitzner; Michael Huhn; Stefanie Sasse; P Mallmann; Andreas Engert; Stefan Barth
Construction of phage display libraries from reactive lymph nodes of breast carcinoma patients and selection for specifically binding human single chain Fv on cell lines.
International journal of molecular medicine 2004;14(4):729-35.
2004: Bärbel Matthey; Peter Borchmann; Roland Schnell; Samir Tawadros; Hans Lange; Michael Huhn; Alexander Klimka; Mehmet K Tur; Stefan Barth; Andreas Engert; Hinrich P Hansen
Metalloproteinase inhibition augments antitumor efficacy of the anti-CD30 immunotoxin Ki-3(scFv)-ETA' against human lymphomas in vivo.
International journal of cancer. Journal international du cancer 2004;111(4):568-74.
2004: Claudia Heuser; Stefan Guhlke; Alexander Matthies; Hans Bender; Stefan Barth; Volker Diehl; Hinrich Abken; Andreas Hombach
Anti-CD30-scFv-Fc-IL-2 antibody-cytokine fusion protein that induces resting NK cells to highly efficient cytolysis of Hodgkin's lymphoma derived tumour cells.
International journal of cancer. Journal international du cancer 2004;110(3):386-94.
2003: Mehmet K Tur; Michael Huhn; Theo Thepen; Michael Stöcker; Regina Krohn; Simon Vogel; Edgar Jost; Rainhardt Osieka; Jan G J van de Winkel; Rainer Fischer; Ricarda Finnern; Stefan Barth
Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells.
Cancer research 2003;63(23):8414-9.
2003: Daniela Bruell; Michael Stöcker; Michael Huhn; Nicole Redding; Michael Küpper; Petra Schumacher; Antje Paetz; Christiane J Bruns; Hidde J Haisma; Rainer Fischer; Ricarda Finnern; Stefan Barth
The recombinant anti-EGF receptor immunotoxin 425(scFv)-ETA' suppresses growth of a highly metastatic pancreatic carcinoma cell line.
International journal of oncology 2003;23(4):1179-86.
2003: Michael Stöcker; Mehmet K Tur; Stefanie Sasse; Anne Krüssmann; Stefan Barth; Andreas Engert
Secretion of functional anti-CD30-angiogenin immunotoxins into the supernatant of transfected 293T-cells.
Protein expression and purification 2003;28(2):211-9.
2003: Mehmet K Tur; Achim Rothe; Michael Huhn; Ute Goerres; Alexander Klimka; Michael Stöcker; Andreas Engert; Rainerr Fischer; Ricarda Finner; Stefan Barth
A novel approach for immunization, screening and characterization of selected scFv libraries using membrane fractions of tumor cells.
International journal of molecular medicine 2003;11(4):523-7.
2002: T Pfitzner; Marcel Reiser; Stefan Barth; Peter Borchmann; Holger Schulz; Timo Schinköthe; F Oberhäuser; J Wessels; Mehmet K Tur; Volker Diehl; Andreas Engert
Quantitative molecular monitoring of residual tumor cells in chronic lymphocytic leukemia.
Annals of hematology 2002;81(5):258-66.
2002: Hinrich P Hansen; Bärbel Matthey; Stefan Barth; Tatiana Kisseleva; Thilo Mokros; Stephen J Davies; R Paul Beckett; Regina Foelster-Holst; Hans H Lange; Andreas Engert; Hilmar Lemke
Inhibition of metalloproteinases enhances the internalization of anti-CD30 antibody Ki-3 and the cytotoxic activity of Ki-3 immunotoxin.
International journal of cancer. Journal international du cancer 2002;98(2):210-5.
2002: K Pfister; B M Wittig; Bernhard Jüngling; Karl-Walter Ecker; Stefan Barth; Michael Huhn; Stefanie Sasse; Andreas Engert; Ina Mueller-Molaian; V Diehl; Martin Zeitz; Andreas Stallmach
The in vitro anti-inflammatory effects of recombinant anti-CD25 immunotoxin on lamina propria T cells of patients with inflammatory bowel disease are not sufficient to cure experimental colitis in mice.
International journal of colorectal disease 2002;17(2):77-84.
2001: Michael Huhn; Stefanie Sasse; Mehmet K Tur; Bärbel Matthey; Timo Schinköthe; S M Rybak; Stefan Barth; Andreas Engert
Human angiogenin fused to human CD30 ligand (Ang-CD30L) exhibits specific cytotoxicity against CD30-positive lymphoma.
Cancer research 2001;61(24):8737-42.
2001: Mehmet K Tur; Stefanie Sasse; Michael Stöcker; K Djabelkhir; Michael Huhn; Bärbel Matthey; C Gottstein; T Pfitzner; Andreas Engert; Stefan Barth
An anti-GD2 single chain Fv selected by phage display and fused to Pseudomonas exotoxin A develops specific cytotoxic activity against neuroblastoma derived cell lines.
International journal of molecular medicine 2001;8(5):579-84.
2001: Mehmet K Tur; Michael Huhn; Stefanie Sasse; Andreas Engert; Stefan Barth
Selection of scFv phages on intact cells under low pH conditions leads to a significant loss of insert-free phages.
BioTechniques 2001;30(2):404-8, 410, 412-3.
2000: Bärbel Matthey; Andreas Engert; Stefan Barth
Recombinant immunotoxins for the treatment of Hodgkin's disease (Review).
International journal of molecular medicine 2000;6(5):509-14.
2000: Alexander Klimka; Bärbel Matthey; Rob C Roovers; Stefan Barth; Jan-Willem Arends; Andreas Engert; Hennie Hoogenboom
Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning.
British journal of cancer 2000;83(2):252-60.
2000: Stefan Barth; Michael Huhn; Bärbel Matthey; Samir Tawadros; Roland Schnell; Timo Schinköthe; Volker Diehl; Andreas Engert
Ki-4(scFv)-ETA', a new recombinant anti-CD30 immunotoxin with highly specific cytotoxic activity against disseminated Hodgkin tumors in SCID mice.
Blood 2000;95(12):3909-14.
2000: Stefan Barth; Michael Huhn; Bärbel Matthey; Roland Schnell; Samir Tawadros; Timo Schinköthe; Johann Lorenzen; Volker Diehl; Andreas Engert
Recombinant anti-CD25 immunotoxin RFT5(SCFV)-ETA' demonstrates successful elimination of disseminated human Hodgkin lymphoma in SCID mice.
International journal of cancer. Journal international du cancer 2000;86(5):718-24.
2000: T Pfitzner; Andreas Engert; H Wittor; Timo Schinköthe; F Oberhäuser; Holger Schulz; Volker Diehl; Stefan Barth
A real-time PCR assay for the quantification of residual malignant cells in B cell chronic lymphatic leukemia.
Leukemia 2000;14(4):754-66.
2000: Stefan Barth; Michael Huhn; Bärbel Matthey; Alexander Klimka; E A Galinski; Andreas Engert
Compatible-solute-supported periplasmic expression of functional recombinant proteins under stress conditions.
Applied and environmental microbiology 2000;66(4):1572-9.
2000: Roland Schnell; Ellen S Vitetta; John Schindler; Peter Borchmann; Stefan Barth; Victor Ghetie; K Hell; S Drillich; Volker Diehl; Andreas Engert
Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin.
Leukemia 2000;14(1):129-35.
1999: Stefan Barth; Bärbel Matthey; Michael Huhn; Volker Diehl; Andreas Engert
CD30L-ETA': a new recombinant immunotoxin based on the CD30 ligand for possible use against human lymphoma.
Cytokines, cellular & molecular therapy 1999;5(2):69-78.
1999: Alexander Klimka; Stefan Barth; Bärbel Matthey; Rob C Roovers; Hilmar Lemke; Hinrich Hansen; Jan-Willem Arends; Volker Diehl; Hennie Hoogenboom; Andreas Engert
An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA') is a potent immunotoxin against a Hodgkin-derived cell line.
British journal of cancer 1999;80(8):1214-22.
1999: Bärbel Matthey; Andreas Engert; Alexander Klimka; Volker Diehl; Stefan Barth
A new series of pET-derived vectors for high efficiency expression of Pseudomonas exotoxin-based fusion proteins.
Gene 1999;229(1-2):145-53.
1998: Roland Schnell; Ellen S Vitetta; John Schindler; Stefan Barth; U Winkler; Peter Borchmann; M L Hansmann; Volker Diehl; Victor Ghetie; Andreas Engert
Clinical trials with an anti-CD25 ricin A-chain experimental and immunotoxin (RFT5-SMPT-dgA) in Hodgkin's lymphoma.
Leukemia & lymphoma 1998;30(5-6):525-37.
1998: Stefan Barth; Michael Huhn; W Wels; Volker Diehl; Andreas Engert
Construction and in vitro evaluation of RFT5(scFv)-ETA', a new recombinant single-chain immunotoxin with specific cytotoxicity toward CD25+ Hodgkin-derived cell lines.
International journal of molecular medicine 1998;1(1):249-56.
1997: Stefan Barth; U Winkler; Volker Diehl; Andreas Engert
[Immunotoxins. Mechanism of action and applications in malignant diseases].
Der Internist 1997;38(11):1063-9.
1997: Roland Schnell; Stefan Barth; Volker Diehl; Andreas Engert
Non-Hodgkin's Lymphoma: A Review of Immunotherapeutic Approaches to Treatment.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 1997;8(3):216-34.
1997: Andreas Engert; Roland Schnell; Stefan Barth; Volker Diehl
[Immunotherapy strategies in lymphoma].
Der Internist 1997;38(2):150-6.
1997: Andreas Engert; Volker Diehl; Roland Schnell; A Radszuhn; M T Hatwig; S Drillich; G Schön; Heribert Bohlen; Hans Tesch; M L Hansmann; Stefan Barth; John Schindler; Victor Ghetie; Jonathan Uhr; Ellen S Vitetta
A phase-I study of an anti-CD25 ricin A-chain immunotoxin (RFT5-SMPT-dgA) in patients with refractory Hodgkin's lymphoma.
Blood 1997;89(2):403-10.
1997: U Winkler; Stefan Barth; Roland Schnell; Volker Diehl; Andreas Engert
The emerging role of immunotoxins in leukemia and lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8 Suppl 1():139-46.
1996: Alexander Klimka; Stefan Barth; S Drillich; W Wels; J van Snick; J C Renauld; H Tesch; Heribert Bohlen; Volker Diehl; Andreas Engert
A deletion mutant of Pseudomonas exotoxin-A fused to recombinant human interleukin-9 (rhIL-9-ETA') shows specific cytotoxicity against IL-9-receptor-expressing cell lines.
Cytokines and molecular therapy 1996;2(3):139-46.
1996: Roland Schnell; Stefan Barth; Volker Diehl; Andreas Engert
Hodgkin's disease. Future treatment strategies: fact or fiction?
Baillière's clinical haematology 1996;9(3):573-93.
1996: Roland Schnell; A A Katouzi; C Linnartz; G Schoen; S Drillich; Martin-Leo Hansmann; D Schiefer; Stefan Barth; Uwe Zangemeister-Wittke; Rolf A Stahel; Volker Diehl; Andreas Engert
Potent anti-tumor effects of an anti-CD24 ricin A-chain immunotoxin in vitro and in a disseminated human Burkitt's lymphoma model in SCID mice.
International journal of cancer. Journal international du cancer 1996;66(4):526-31.
1996: Stefan Barth; Roland Schnell; Volker Diehl; Andreas Engert
Development of immunotoxins for potential clinical use in Hodgkin's disease.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7 Suppl 4():135-41.