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Paul MacDonald

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Chi Zhang; Diane R Dowd; Yang Li; Wanjin Tang; Fan Yang; Paul N MacDonald
Osteoblast-specific transcription factor Osterix increases vitamin D receptor gene expression in osteoblasts.
Diane R Dowd; Paul N MacDonald
The 1,25-dihydroxyvitamin D3-independent actions of the vitamin D receptor in skin.
Xiaoxue Zhang; Diane R Dowd; Meika C Moore; Tanya A Kranenburg; Magda A Meester-Smoor; Ellen C Zwarthoff; Paul N MacDonald
Meningioma 1 is required for appropriate osteoblast proliferation, motility, differentiation, and function.

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All Publications

2011: Chi Zhang; Diane R Dowd; Yang Li; Wanjin Tang; Fan Yang; Paul N MacDonald
Osteoblast-specific transcription factor Osterix increases vitamin D receptor gene expression in osteoblasts.
PloS one 2011;6(10):e26504.
2010: Diane R Dowd; Paul N MacDonald
The 1,25-dihydroxyvitamin D3-independent actions of the vitamin D receptor in skin.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):317-21.
2009: Xiaoxue Zhang; Diane R Dowd; Meika C Moore; Tanya A Kranenburg; Magda A Meester-Smoor; Ellen C Zwarthoff; Paul N MacDonald
Meningioma 1 is required for appropriate osteoblast proliferation, motility, differentiation, and function.
The Journal of biological chemistry 2009;284(27):18174-83.
2008: Tara I Ellison; Molly K Smith; Anita Gilliam; Paul N MacDonald
Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis.
The Journal of investigative dermatology 2008;128(10):2508-17.
2008: Amelia L M Sutton; Xiaoxue Zhang; Diane R Dowd; Yogendra P Kharode; Barry S Komm; Paul N MacDonald
Semaphorin 3B is a 1,25-Dihydroxyvitamin D3-induced gene in osteoblasts that promotes osteoclastogenesis and induces osteopenia in mice.
Molecular endocrinology (Baltimore, Md.) 2008;22(6):1370-81.
2007: Tara I Ellison; Richard L Eckert; Paul N MacDonald
Evidence for 1,25-dihydroxyvitamin D3-independent transactivation by the vitamin D receptor: uncoupling the receptor and ligand in keratinocytes.
The Journal of biological chemistry 2007;282(15):10953-62.
2007: Marie B Demay; Paul N MacDonald; Kristi Skorija; Diane R Dowd; Luisella Cianferotti; Megan Cox
Role of the vitamin D receptor in hair follicle biology.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):344-6.
2005: Erin L Milliken; Xiaoxue Zhang; Chris A Flask; Jeffrey L Duerk; Paul N MacDonald; Ruth A Keri
EB1089, a vitamin D receptor agonist, reduces proliferation and decreases tumor growth rate in a mouse model of hormone-induced mammary cancer.
Cancer letters 2005;229(2):205-15.
2005: Tara I Ellison; Diane R Dowd; Paul N MacDonald
Calmodulin-dependent kinase IV stimulates vitamin D receptor-mediated transcription.
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2309-19.
2005: Amelia L M Sutton; Xiaoxue Zhang; Tara I Ellison; Paul N MacDonald
The 1,25(OH)2D3-regulated transcription factor MN1 stimulates vitamin D receptor-mediated transcription and inhibits osteoblastic cell proliferation.
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2234-44.
2005: Kristi Skorija; Megan Cox; Jeanne Sisk; Diane R Dowd; Paul N MacDonald; Catherine C Thompson; Marie B Demay
Ligand-independent actions of the vitamin D receptor maintain hair follicle homeostasis.
Molecular endocrinology (Baltimore, Md.) 2005;19(4):855-62.
2005: Puneet Dhawan; Xiaorong Peng; Amelia L M Sutton; Paul N MacDonald; Colleen Croniger; Christian Trautwein; Michael Centrella; Thomas L McCarthy; Sylvia Christakos
Functional cooperation between CCAAT/enhancer-binding proteins and the vitamin D receptor in regulation of 25-hydroxyvitamin D3 24-hydroxylase.
Molecular and cellular biology 2005;25(1):472-87.
2004: Paul N MacDonald; Diane R Dowd; Chi Zhang; Chun Gu
Emerging insights into the coactivator role of NCoA62/SKIP in Vitamin D-mediated transcription.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):179-86.
2003: Chi Zhang; Diane R Dowd; Ada Staal; Chun Gu; Jane B Lian; Andre J van Wijnen; Gary S Stein; Paul N MacDonald
Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing.
The Journal of biological chemistry 2003;278(37):35325-36.
2003: Amelia L M Sutton; Paul N MacDonald
Vitamin D: more than a "bone-a-fide" hormone.
Molecular endocrinology (Baltimore, Md.) 2003;17(5):777-91.
2001: Chi Zhang; Troy A Baudino; Diane R Dowd; H Tokumaru; W Wang; Paul N MacDonald
Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription.
The Journal of biological chemistry 2001;276(44):40614-20.
2001: Paul N MacDonald; Troy A Baudino; H Tokumaru; Diane R Dowd; Chi Zhang
Vitamin D receptor and nuclear receptor coactivators: crucial interactions in vitamin D-mediated transcription.
Steroids 2001;66(3-5):171-6.
2001: DM Kraichely; Paul N MacDonald
Confirming yeast two-hybrid protein interactions using in vitro glutathione-S-transferase pulldowns.
Methods in molecular biology (Clifton, N.J.) 2001;177():135-50.
2000: Nanhai Chen; Troy A Baudino; Paul N MacDonald; Maurice Green; W L Kelley; Joseph W Burnett; R Mark L Buller
Selective inhibition of nuclear steroid receptor function by a protein from a human tumorigenic poxvirus.
Virology 2000;274(1):17-25.
2000: Hisashi Masuyama; Yuji Hiramatsu; M Kunitomi; Takafumi Kudo; Paul N MacDonald
Endocrine disrupting chemicals, phthalic acid and nonylphenol, activate Pregnane X receptor-mediated transcription.
Molecular endocrinology (Baltimore, Md.) 2000;14(3):421-8.
1999: DM Kraichely; Y D Nakai; Paul N MacDonald
Identification of an autonomous transactivation domain in helix H3 of the vitamin D receptor.
Journal of cellular biochemistry 1999;75(1):82-92.
1999: DM Kraichely; J J Collins; Robert DeLisle; Paul N MacDonald
The autonomous transactivation domain in helix H3 of the vitamin D receptor is required for transactivation and coactivator interaction.
The Journal of biological chemistry 1999;274(20):14352-8.
1998: Hisashi Masuyama; Paul N MacDonald
Proteasome-mediated degradation of the vitamin D receptor (VDR) and a putative role for SUG1 interaction with the AF-2 domain of VDR.
Journal of cellular biochemistry 1998;71(3):429-40.
1998: Troy A Baudino; DM Kraichely; Stephen Jefcoat; SK Winchester; Nicola C Partridge; Paul N MacDonald
Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription.
The Journal of biological chemistry 1998;273(26):16434-41.
1998: DM Kraichely; Paul N MacDonald
Transcriptional activation through the vitamin D receptor in osteoblasts.
Frontiers in bioscience : a journal and virtual library 1998;3():d821-33.
1998: Paul N MacDonald
A two-hybrid protein interaction system to identify factors that interact with retinoid and vitamin D receptors.
Methods in molecular biology (Clifton, N.J.) 1998;89():359-75.
1997: Hisashi Masuyama; C M Brownfield; R St-Arnaud; Paul N MacDonald
Evidence for ligand-dependent intramolecular folding of the AF-2 domain in vitamin D receptor-activated transcription and coactivator interaction.
Molecular endocrinology (Baltimore, Md.) 1997;11(10):1507-17.
1997: Diane R Dowd; Jan S Ryerse; Paul N MacDonald; R L Miesfeld; M C Kamradt
Crosstalk during Ca2+-, cAMP-, and glucocorticoid-induced gene expression in lymphocytes.
Molecular and cellular endocrinology 1997;128(1-2):29-37.
1997: Hisashi Masuyama; Stephen Jefcoat; Paul N MacDonald
The N-terminal domain of transcription factor IIB is required for direct interaction with the vitamin D receptor and participates in vitamin D-mediated transcription.
Molecular endocrinology (Baltimore, Md.) 1997;11(2):218-28.
1997: E Martinez; D D Moore; E Keller; D Pearce; Vincent Jb Robinson; Paul N MacDonald; S S Simons; E Sanchez; Mark Danielsen
The Nuclear Receptor Resource Project.
Nucleic acids research 1997;25(1):163-5.
1996: Y S Kim; Paul N MacDonald; S Dedhar; Keith A Hruska
Association of 1 alpha,25-dihydroxyvitamin D3-occupied vitamin D receptors with cellular membrane acceptance sites.
Endocrinology 1996;137(9):3649-58.
1996: Eduardo Slatopolsky; J Finch; M Denda; C Ritter; M Zhong; Adriana S Dusso; Paul N MacDonald; AJ Brown
Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro.
The Journal of clinical investigation 1996;97(11):2534-40.
1995: G Kerr Whitfield; Jui-Cheng Hsieh; S Nakajima; Paul N MacDonald; Paul D Thompson; Peter Jurutka; Carol A Haussler; Mark R Haussler
A highly conserved region in the hormone-binding domain of the human vitamin D receptor contains residues vital for heterodimerization with retinoid X receptor and for transcriptional activation.
Molecular endocrinology (Baltimore, Md.) 1995;9(9):1166-79.
1995: G Kerr Whitfield; Jui-Cheng Hsieh; Peter Jurutka; S H Selznick; Carol A Haussler; Paul N MacDonald; Mark R Haussler
Genomic actions of 1,25-dihydroxyvitamin D3.
The Journal of nutrition 1995;125(6 Suppl):1690S-1694S.
1995: Paul N MacDonald; D R Sherman; Diane R Dowd; Stephen Jefcoat; Robert DeLisle
The vitamin D receptor interacts with general transcription factor IIB.
The Journal of biological chemistry 1995;270(9):4748-52.
1994: Paul N MacDonald; Diane R Dowd; Mark R Haussler
New insight into the structure and functions of the vitamin D receptor.
Seminars in nephrology 1994;14(2):101-18.
1994: S Nakajima; Jui-Cheng Hsieh; Paul N MacDonald; Michael A Galligan; Carol A Haussler; G Kerr Whitfield; Mark R Haussler
The C-terminal region of the vitamin D receptor is essential to form a complex with a receptor auxiliary factor required for high affinity binding to the vitamin D-responsive element.
Molecular endocrinology (Baltimore, Md.) 1994;8(2):159-72.
1994: Paul N MacDonald; C Ritter; AJ Brown; Eduardo Slatopolsky
Retinoic acid suppresses parathyroid hormone (PTH) secretion and PreproPTH mRNA levels in bovine parathyroid cell culture.
The Journal of clinical investigation 1994;93(2):725-30.
1993: S Nakajima; Jui-Cheng Hsieh; Paul N MacDonald; Carol A Haussler; Michael A Galligan; Peter Jurutka; Mark R Haussler
Purified human vitamin D receptor overexpressed in E. coli and baculovirus systems does not bind 1,25-dihydroxyvitamin D3 hormone efficiently unless supplemented with a rat liver nuclear extract.
Biochemical and biophysical research communications 1993;197(2):478-85.
1993: Paul N MacDonald; Diane R Dowd; S Nakajima; Michael A Galligan; M C Reeder; Carol A Haussler; Keiko Ozato; Mark R Haussler
Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene.
Molecular and cellular biology 1993;13(9):5907-17.
1993: Peter Jurutka; Jui-Cheng Hsieh; Paul N MacDonald; C M Terpening; Carol A Haussler; Mark R Haussler; G Kerr Whitfield
Phosphorylation of serine 208 in the human vitamin D receptor. The predominant amino acid phosphorylated by casein kinase II, in vitro, and identification as a significant phosphorylation site in intact cells.
The Journal of biological chemistry 1993;268(9):6791-9.
1992: Diane R Dowd; Paul N MacDonald; B S Komm; Mark R Haussler; Roger L Miesfeld
Stable expression of the calbindin-D28K complementary DNA interferes with the apoptotic pathway in lymphocytes.
Molecular endocrinology (Baltimore, Md.) 1992;6(11):1843-8.
1992: Paul N MacDonald; G Kerr Whitfield; Carol A Haussler; A M Hocker; Mark R Haussler; B S Komm
Evaluation of a putative vitamin D response element in the avian calcium binding protein gene.
DNA and cell biology 1992;11(5):377-83.
1991: Diane R Dowd; Paul N MacDonald; B S Komm; Mark R Haussler; Roger L Miesfeld
Evidence for early induction of calmodulin gene expression in lymphocytes undergoing glucocorticoid-mediated apoptosis.
The Journal of biological chemistry 1991;266(28):18423-6.
1991: Paul N MacDonald; Carol A Haussler; C M Terpening; Michael A Galligan; M C Reeder; G Kerr Whitfield; Mark R Haussler
Baculovirus-mediated expression of the human vitamin D receptor. Functional characterization, vitamin D response element interactions, and evidence for a receptor auxiliary factor.
The Journal of biological chemistry 1991;266(28):18808-13.