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François Mach

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F Carbone; François Mach; Alessio Nencioni; N Vuilleumier; Fabrizio Montecucco
Evidence on the pathogenic role of auto-antibodies in acute cardiovascular diseases.
N Vuilleumier; B Pane; Aldo Pende; Pascale Roux-Lombard; G Spinella; Maria Bertolotto; Christophe Combescure; Franco Dallegri; K Galan; François Mach; Fabrizio Montecucco; S Pagano; Domenico Palombo
Serum levels of anti-apolipoprotein A-1 auto-antibodies and myeloperoxidase as predictors of major adverse cardiovascular events after carotid endarterectomy.
Fabrizio Montecucco; Christophe Montessuit; Raul Mostoslavsky; Franco Patrone; Graziano Pelli; Corinne Pellieux; Alessandro Poggi; Carlos Sebastian; Timo Speer; Nicolas Vuilleumier; Alexander Akhmedov; Inga Bauer; Maria Bertolotto; Vincent Braunersreuther; Santina Bruzzone; Franco Dallegri; Katia Galan; Anna Garuti; Angèle Gayet-Ageron; Sébastien Lenglet; René Lerch; Thomas F Lüscher; François Mach; Jacqueline Mage; Elena Mannino; Alessio Nencioni
Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction.

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All Publications

2013: F Carbone; François Mach; Alessio Nencioni; N Vuilleumier; Fabrizio Montecucco
Evidence on the pathogenic role of auto-antibodies in acute cardiovascular diseases.
Thrombosis and haemostasis 2013;109(5):854-68.
2013: N Vuilleumier; B Pane; Aldo Pende; Pascale Roux-Lombard; G Spinella; Maria Bertolotto; Christophe Combescure; Franco Dallegri; K Galan; François Mach; Fabrizio Montecucco; S Pagano; Domenico Palombo
Serum levels of anti-apolipoprotein A-1 auto-antibodies and myeloperoxidase as predictors of major adverse cardiovascular events after carotid endarterectomy.
Thrombosis and haemostasis 2013;109(4):706-15.
2013: Fabrizio Montecucco; Christophe Montessuit; Raul Mostoslavsky; Franco Patrone; Graziano Pelli; Corinne Pellieux; Alessandro Poggi; Carlos Sebastian; Timo Speer; Nicolas Vuilleumier; Alexander Akhmedov; Inga Bauer; Maria Bertolotto; Vincent Braunersreuther; Santina Bruzzone; Franco Dallegri; Katia Galan; Anna Garuti; Angèle Gayet-Ageron; Sébastien Lenglet; René Lerch; Thomas F Lüscher; François Mach; Jacqueline Mage; Elena Mannino; Alessio Nencioni
Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction.
Antioxidants & redox signaling 2013;18(6):630-41.
2013: Mohamed Asrih; Sébastien Lenglet; François Mach; Fabrizio Montecucco
Alpha-fetoprotein: a controversial prognostic biomarker for small hepatocellular carcinoma.
World journal of gastroenterology : WJG 2013;19(3):328-30.
2013: Mohamed Asrih; Franco Dallegri; François Mach; Alessandra Quercioli; Fabrizio Montecucco
Update on the pathophysiological activities of the cardiac molecule cardiotrophin-1 in obesity.
Mediators of inflammation 2013;2013():370715.
2013: Sébastien Lenglet; François Mach; Fabrizio Montecucco
Role of matrix metalloproteinase-8 in atherosclerosis.
Mediators of inflammation 2013;2013():659282.
2013: Alessandra Puddu; Giorgio Luciano Viviani; François Mach; Alessio Nencioni; Fabrizio Montecucco
An emerging role of glucagon-like peptide-1 in preventing advanced-glycation-end-product-mediated damages in diabetes.
Mediators of inflammation 2013;2013():591056.
2013: Mohamed Asrih; Franco Dallegri; François Mach; Alessio Nencioni; Alessandra Quercioli; Fabrizio Montecucco
Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndrome.
Mediators of inflammation 2013;2013():367245.
2012: Sébastien Lenglet; François Mach; Fabrizio Montecucco
Matrix metalloproteinase-9: a deleterious link between hepatic ischemia-reperfusion and colorectal cancer.
World journal of gastroenterology : WJG 2012;18(48):7131-3.
2012: Delphine Michel-Monigadon; Filippo Molica; François Mach; Sabine Steffens; Fabrizio Montecucco
Update on the endocannabinoid-mediated regulation of gelatinase release in arterial wall physiology and atherosclerotic pathophysiology.
Expert review of cardiovascular therapy 2012;10(12):1481-6.
2012: Alessandra Quercioli; Osman Ratib; Christian Staub; Aurélien Thomas; Gabriella Vincenti; Giuseppe Ambrosio; Sebastian Carballo; Vincenzo Di Marzo; Alain Golay; Elisabetta Harsch; François Mach; Fabrizio Montecucco; Zoltan Pataky; Thomas H Schindler
Coronary vasomotor control in obesity and morbid obesity: contrasting flow responses with endocannabinoids, leptin, and inflammation.
JACC. Cardiovascular imaging 2012;5(8):805-15.
2012: Anna Pfenniger; Esther Sutter; Cindy Wong; François Mach; Simon Cuhlmann; Sylvie Dunoyer-Geindre; Paul C Evans; Anton J Horrevoets; Rob Krams; Brenda R Kwak
Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells.
Journal of molecular and cellular cardiology 2012;53(2):299-309.
2012: Gabriella M Vincenti; Yann Seimbille; Jean-Paul Vallée; Giuseppe Ambrosio; Jean-Noël Hyacinthe; François Mach; Alessandra Quercioli; Osman Ratib; Thomas H Schindler
Matching between regional coronary vasodilator capacity and corresponding circumferential strain in individuals with normal and increasing body weight.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2012;19(4):693-703.
2012: Fabrizio Montecucco; Graziano Pelli; Jean-Paul Vallée; Nicolas Vuilleumier; Vincent Braunersreuther; Vanessa Buatois; Benedicte MA Delattre; Walter Ferlin; Nicolas Fischer; Katia Galan; Florence Guilhot; Marie H Kosco-Vilbois; Sébastien Lenglet; François Mach
CC chemokine CCL5 plays a central role impacting infarct size and post-infarction heart failure in mice.
European heart journal 2012;33(15):1964-74.
2012: Jean-Luc Reny; Jean-François Schved; Isabelle Barazer; Philippe Berdagué; Henri Bounameaux; Philippe de Moerloose; Pascale Fabbro-Peray; Pierre Fontana; François Mach; Séverine Nolli; Antoine Poncet
Antiplatelet drug response status does not predict recurrent ischemic events in stable cardiovascular patients: results of the Antiplatelet Drug Resistances and Ischemic Events study.
Circulation 2012;125(25):3201-10.
2012: Anna Pfenniger; Sander W. van der Laan; Stephan Winnik; François Mach; Gerard Pasterkamp; Sylvie Dunoyer-Geindre; Bernard Foglia; Jacques-Antoine Haefliger; Richard W James; Brenda R Kwak
Lack of association between connexin40 polymorphisms and coronary artery disease.
Atherosclerosis 2012;222(1):148-53.
2012: Pierre-Frédéric Keller; François Mach; S Pagano; P Roux-Lombard; O T Rutschmann; Philippe Sigaud; Denis Hochstrasser; N Vuilleumier
Autoantibodies against apolipoprotein A-1 and phosphorylcholine for diagnosis of non-ST-segment elevation myocardial infarction.
Journal of internal medicine 2012;271(5):451-62.
2012: Fabrizio Montecucco; Sabrina Pagano; Domenico Palombo; Bianca Pane; Graziano Pelli; Aldo Pende; Lucie Pilet; Fabiana Piscitelli; Silvia Quintao; Pascale Roux-Lombard; Robson A S Santos; Giovanni Spinella; Sabine Steffens; Nikos Stergiopulos; Giorgio Luciano Viviani; Nicolas Vuilleumier; Maria Bertolotto; Vincent Braunersreuther; Fabienne Burger; Luciano Capettini; Rafaela F da Silva; Franco Dallegri; Vincenzo Di Marzo; Katia Galan; Angèle Gayet-Ageron; Kristina Kuzmanovic; Sébastien Lenglet; François Mach
The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques.
European heart journal 2012;33(7):846-56.
2012: Benedicte MA Delattre; Jean-Noël Hyacinthe; René Lerch; François Mach; Corinne Pellieux; Vincent Braunersreuther; Dimitri Van De Ville; Jean-Paul Vallée
High time-resolved cardiac functional imaging using temporal regularization for small animal on a clinical 3T scanner.
IEEE transactions on bio-medical engineering 2012;59(4):929-35.
2012: Benedicte MA Delattre; Stéphany Gardier; Jean-Noël Hyacinthe; François Mach; Vincent Braunersreuther; Lindsey A Crowe; Jean-Paul Vallée
Manganese kinetics demonstrated double contrast in acute but not in chronic infarction in a mouse model of myocardial occlusion reperfusion.
NMR in biomedicine 2012;25(4):489-97.
2012: Sébastien Lenglet; François Mach; Pierre Chaurand; Katia Galan; Aurélien Thomas; Fabrizio Montecucco
Molecular imaging of matrix metalloproteinases in atherosclerotic plaques.
Thrombosis and haemostasis 2012;107(3):409-16.
2012: Michel F Rossier; Pascale Roux-Lombard; Richard W James; François Mach; Andrés Maturana; Sabrina Pagano; Magaly Python; Nicolas Vuilleumier
Antiapolipoprotein A-1 IgG chronotropic effects require nongenomic action of aldosterone on L-type calcium channels.
Endocrinology 2012;153(3):1269-78.
2012: Albane B R Maggio; Laetitia M Marchand; Fabrizio Montecucco; Graziano Pelli; Valerie M Schwitzgebel; Yacine Aggoun; Nathalie J Farpour-Lambert; François Mach; Maurice Beghetti
Elevated E-selectin and diastolic blood pressure in diabetic children.
European journal of clinical investigation 2012;42(3):303-9.
2012: Vincent Braunersreuther; François Mach; Giorgio Luciano Viviani; Fabrizio Montecucco
Role of cytokines and chemokines in non-alcoholic fatty liver disease.
World journal of gastroenterology : WJG 2012;18(8):727-35.
2012: Michel P Kossovsky; François Mach; Pierre-Frederic Keller; Jean-Michel Gaspoz
Fondaparinux versus enoxaprin in the management of acute coronary syndromes in Switzerland: A cost comparison analysis.
Swiss medical weekly 2012;142():w13536.
2012: Vincent Braunersreuther; François Mach; Fabrizio Montecucco
Statins and stent thrombosis.
Swiss medical weekly 2012;142():w13525.
2011: Sébastien Lenglet; François Mach; Fabrizio Montecucco
Methylene blue: potential use of an antique molecule in vasoplegic syndrome during cardiac surgery.
Expert review of cardiovascular therapy 2011;9(12):1519-25.
2011: Fabrizio Montecucco; François Mach
Should we focus on "venous vulnerability" instead of "plaque vulnerability" in symptomatic atherosclerotic patients?
Thrombosis and haemostasis 2011;106(6):995-6.
2011: Siv Fokstuen; Sabino Iliceto; Xavier Jeanrenaud; René Lerch; François Mach; Paola Melacini; Analia Munoz; Cemil Ozcelik; Andreas Perrot; Claudine Rieubland; Ulrich Sigwart; Stylianos E Antonarakis; Lothar Faber; Martin Farr; Jean-Louis Blouin
Rapid detection of genetic variants in hypertrophic cardiomyopathy by custom DNA resequencing array in clinical practice.
Journal of medical genetics 2011;48(8):572-6.
2011: Alessandra Quercioli; Zoltan Pataky; Gabriella Vincenti; V Makoundou; Vincenzo Di Marzo; Fabrizio Montecucco; Sebastian Carballo; Aurélien Thomas; Christian Staub; Sabine Steffens; Yann Seimbille; Alain Golay; Osman Ratib; Elisabetta Harsch; François Mach; Thomas H Schindler
Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity.
European heart journal 2011;32(11):1369-78.
2011: Fabrizio Montecucco; Maria Bertolotto; Nicolas Vuilleumier; Ulisse Franciosi; Alessandra Puddu; Silvia Minetti; Andrea Delrio; Alessandra Quercioli; Ettore Bergamini; Luciano Ottonello; Aldo Pende; Sébastien Lenglet; Graziano Pelli; François Mach; Franco Dallegri; Giorgio Luciano Viviani
Acipimox reduces circulating levels of insulin and associated neutrophilic inflammation in metabolic syndrome.
American journal of physiology. Endocrinology and metabolism 2011;300(4):E681-90.
2011: Marisol Mirabelli-Badenier; Vincent Braunersreuther; Giorgio Luciano Viviani; Franco Dallegri; Alessandra Quercioli; Edvige Veneselli; François Mach; Fabrizio Montecucco
CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke.
Thrombosis and haemostasis 2011;105(3):409-20.
2011: Fabrizio Montecucco; Nicolas Vuilleumier; Sabrina Pagano; Sébastien Lenglet; Maria Bertolotto; Vincent Braunersreuther; Graziano Pelli; Enikö Kovari; Bianca Pane; Giovanni Spinella; Aldo Pende; Domenico Palombo; Franco Dallegri; François Mach; Pascale Roux-Lombard
Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability.
European heart journal 2011;32(4):412-21.
2011: Isabelle Brochériou; Maouche Seraya; Hervé Durand; Vincent Braunersreuther; Gilles Le Naour; Alexei Gratchev; Fabien Koskas; François Mach; Julia Kzhyshkowska; Ewa Ninio
Antagonistic regulation of macrophage phenotype by M-CSF and GM-CSF: implication in atherosclerosis.
Atherosclerosis 2011;214(2):316-24.
2011: Fabrizio Montecucco; Aldo Pende; Alessandra Quercioli; François Mach
Inflammation in the pathophysiology of essential hypertension.
Journal of nephrology 2011;24(1):23-34.
2010: Alessandra Quercioli; Giorgio Luciano Viviani; Franco Dallegri; François Mach; Fabrizio Montecucco
Receptor activator of nuclear factor kappa B ligand/osteoprotegerin pathway is a promising target to reduce atherosclerotic plaque calcification.
Critical pathways in cardiology 2010;9(4):227-30.
2010: Pierre Fontana; P Berdagué; C Castelli; S Nolli; I Barazer; P Fabbro-Peray; J-F Schved; Henri Bounameaux; François Mach; Philippe de Moerloose; J-L Reny
Clinical predictors of dual aspirin and clopidogrel poor responsiveness in stable cardiovascular patients from the ADRIE study.
Journal of thrombosis and haemostasis : JTH 2010;8(12):2614-23.
2010: Fabrizio Montecucco; Alessandra Quercioli; Franco Dallegri; Giorgio Luciano Viviani; François Mach
New evidence for nicotinic acid treatment to reduce atherosclerosis.
Expert review of cardiovascular therapy 2010;8(10):1457-67.
2010: Nicolas Vuilleumier; Sylvette Bas; Sabrina Pagano; Fabrizio Montecucco; Pierre-André Guerne; Axel Finckh; Christian Lovis; François Mach; Denis Hochstrasser; Pascale Roux-Lombard; Cem Gabay
Anti-apolipoprotein A-1 IgG predicts major cardiovascular events in patients with rheumatoid arthritis.
Arthritis and rheumatism 2010;62(9):2640-50.
2010: Alessandra Quercioli; François Mach; Fabrizio Montecucco
Inflammation accelerates atherosclerotic processes in obstructive sleep apnea syndrome (OSAS).
Sleep & breathing = Schlaf & Atmung 2010;14(3):261-9.
2010: Aurélien Thomas; Julien Déglon; Sébastien Lenglet; François Mach; Patrice Mangin; Jean-Luc Wolfender; Sabine Steffens; Christian Staub
High-throughput phospholipidic fingerprinting by online desorption of dried spots and quadrupole-linear ion trap mass spectrometry: evaluation of atherosclerosis biomarkers in mouse plasma.
Analytical chemistry 2010;82(15):6687-94.
2010: Fabrizio Montecucco; Sébastien Lenglet; Angèle Gayet-Ageron; Maria Bertolotto; Graziano Pelli; Domenico Palombo; Bianca Pane; Giovanni Spinella; Sabine Steffens; Lizzia Raffaghello; Vito Pistoia; Luciano Ottonello; Aldo Pende; Franco Dallegri; François Mach
Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke.
Stroke; a journal of cerebral circulation 2010;41(7):1394-404.
2010: Alessandra Quercioli; Fabrizio Montecucco; Maria Bertolotto; Luciano Ottonello; Aldo Pende; François Mach; Franco Dallegri
Coronary artery calcification and cardiovascular risk: the role of RANKL/OPG signalling.
European journal of clinical investigation 2010;40(7):645-54.
2010: Fabrizio Montecucco; Sébastien Lenglet; Vincent Braunersreuther; Graziano Pelli; Corinne Pellieux; Christophe Montessuit; René Lerch; Maud Deruaz; Amanda E I Proudfoot; François Mach
Single administration of the CXC chemokine-binding protein Evasin-3 during ischemia prevents myocardial reperfusion injury in mice.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(7):1371-7.
2010: Benedicte MA Delattre; Vincent Braunersreuther; Jean-Noel Hyacinthe; Lindsey Crowe; François Mach; Jean-Paul Vallée
Myocardial infarction quantification with Manganese-Enhanced MRI (MEMRI) in mice using a 3T clinical scanner.
NMR in biomedicine 2010;23(5):503-13.
2010: Karin Montet-Abou; Jean-Luc Daire; Jean-Noel Hyacinthe; Manuel Jorge-Costa; Kerstin Grosdemange; François Mach; Alke Petri-Fink; Heinrich Hofmann; Denis R Morel; Jean-Paul Vallée; Xavier Montet
In vivo labelling of resting monocytes in the reticuloendothelial system with fluorescent iron oxide nanoparticles prior to injury reveals that they are mobilized to infarcted myocardium.
European heart journal 2010;31(11):1410-20.
2010: Nicolas Vuilleumier; Michel F Rossier; Sabrina Pagano; Magaly Python; Emmanuel Charbonney; René Nkoulou; Richard James; Guido Reber; François Mach; Pascale Roux-Lombard
Anti-apolipoprotein A-1 IgG as an independent cardiovascular prognostic marker affecting basal heart rate in myocardial infarction.
European heart journal 2010;31(7):815-23.
2010: Vincent Braunersreuther; Corinne Pellieux; Graziano Pelli; Fabienne Burger; Sabine Steffens; Christophe Montessuit; Christian Weber; Amanda Proudfoot; François Mach; Claire Arnaud
Chemokine CCL5/RANTES inhibition reduces myocardial reperfusion injury in atherosclerotic mice.
Journal of molecular and cellular cardiology 2010;48(4):789-98.
2010: A Quercioli; François Mach; Fabrizio Montecucco
Novel treatment strategy with direct renin inhibition against heart failure.
Panminerva medica 2010;52(1):41-51.
2010: G Vincenti; A Quercioli; H Zaïdi; René Nkoulou; S Dewarrat; O Rager; G Ambrosio; Y Seimbille; François Mach; Osman Ratib; Thomas H Schindler
Combined evaluation of myocardial perfusion and coronary morphology in the identification of subclinical CAD. Radiation exposure of 13N-ammonia PET/CT.
Nuklearmedizin. Nuclear medicine 2010;49(5):173-82.
2009: Alessandra Quercioli; Fabrizio Montecucco; François Mach
Update on the treatments of non-alcoholic fatty liver disease (NAFLD).
Cardiovascular & hematological disorders drug targets 2009;9(4):261-70.
2009: Robert F Bonvini; Aljoscha Rastan; Sebastian Sixt; Elias Noory; Ulrich Beschorner; Olli Leppanen; François Mach; Uwe Schwarzwälder; Karlheinz Bürgelin; Thomas Zeller
Percutaneous retrieval of intravascular and intracardiac foreign bodies with a dedicated three-dimensional snare: a 3-year single center experience.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2009;74(6):939-45.
2009: Fabrizio Montecucco; Alessandra Quercioli; François Mach
Ezetimibe/simvastatin.
Expert opinion on drug safety 2009;8(6):715-25.
2009: Fabrizio Montecucco; Maria Bertolotto; Luciano Ottonello; Aldo Pende; Patrizia Dapino; A Quercioli; François Mach; Franco Dallegri
Chlorhexidine prevents hypochlorous acid-induced inactivation of alpha1-antitrypsin.
Clinical and experimental pharmacology & physiology 2009;36(11):e72-7.
2009: Sabine Steffens; Fabrizio Montecucco; François Mach
The inflammatory response as a target to reduce myocardial ischaemia and reperfusion injury.
Thrombosis and haemostasis 2009;102(2):240-7.
2009: Fabrizio Montecucco; Isabel Matias; Sébastien Lenglet; Stefania Petrosino; Fabienne Burger; Graziano Pelli; Vincent Braunersreuther; François Mach; Sabine Steffens; Vincenzo Di Marzo
Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis.
Atherosclerosis 2009;205(2):433-41.
2009: Gabriella Vincenti; René Nkoulou; Charles Steiner; Hestia Imperiano; Giuseppe Ambrosio; François Mach; Osman Ratib; Jean-Paul Vallee; Thomas H Schindler
Noninvasive stress testing of myocardial perfusion defects: head-to-head comparison of thallium-201 SPECT to MRI perfusion.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2009;16(4):549-61.
2009: Fabrizio Montecucco; François Mach
Statins, ACE inhibitors and ARBs in cardiovascular disease.
Best practice & research. Clinical endocrinology & metabolism 2009;23(3):389-400.
2009: Fabrizio Montecucco; François Mach
Update on statin-mediated anti-inflammatory activities in atherosclerosis.
Seminars in immunopathology 2009;31(1):127-42.
2009: Fabrizio Montecucco; François Mach
Atherosclerosis is an inflammatory disease.
Seminars in immunopathology 2009;31(1):1-3.
2009: Alexandra Calmy; Angèle Gayet-Ageron; Fabrizio Montecucco; Alain Nguyen; François Mach; Fabienne Burger; Sasiwimol Ubolyam; Andrew Carr; Kiat Ruxungtham; Bernard Hirschel; Jintanat Ananworanich
HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial.
AIDS (London, England) 2009;23(8):929-39.
2009: Maxime Pellegrin; Florian Alonso; Jean-François Aubert; Karima Bouzourene; Vincent Braunersreuther; François Mach; Jacques-Antoine Haefliger; Daniel Hayoz; Alain Berthelot; Jürg Nussberger; Pascal Laurant; Lucia Mazzolai
Swimming prevents vulnerable atherosclerotic plaque development in hypertensive 2-kidney, 1-clip mice by modulating angiotensin II type 1 receptor expression independently from hemodynamic changes.
Hypertension 2009;53(5):782-9.
2009: F Montecucco; François Mach
Update on therapeutic strategies to increase adiponectin function and secretion in metabolic syndrome.
Diabetes, obesity & metabolism 2009;11(5):445-54.
2009: Fabrizio Montecucco; Sébastien Lenglet; Vincent Braunersreuther; Fabienne Burger; Graziano Pelli; Maria Bertolotto; François Mach; Sabine Steffens
CB(2) cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion.
Journal of molecular and cellular cardiology 2009;46(5):612-20.
2009: Robert F Bonvini; Jean-Luc Reny; François Mach; Thomas Zeller; Pierre Fontana
Acute coronary syndrome and its antithrombotic treatment: focus on aspirin and clopidogrel resistance.
Current vascular pharmacology 2009;7(2):198-208.
2009: F Montecucco; Fabienne Burger; Graziano Pelli; N K Poku; C Berlier; Sabine Steffens; François Mach
Statins inhibit C-reactive protein-induced chemokine secretion, ICAM-1 upregulation and chemotaxis in adherent human monocytes.
Rheumatology (Oxford, England) 2009;48(3):233-42.
2009: Fabrizio Montecucco; Maria Bertolotto; Luciano Ottonello; Alessandra Quercioli; François Mach; Franco Dallegri
Oxaprozin-induced apoptosis on CD40 ligand-treated human primary monocytes is associated with the modulation of defined intracellular pathways.
Journal of biomedicine & biotechnology 2009;2009():478785.
2009: Fabrizio Montecucco; Aldo Pende; François Mach
The renin-angiotensin system modulates inflammatory processes in atherosclerosis: evidence from basic research and clinical studies.
Mediators of inflammation 2009;2009():752406.
2009: François Mach; Fabrizio Montecucco; Sabine Steffens
Effect of blockage of the endocannabinoid system by CB(1) antagonism on cardiovascular risk.
Pharmacological reports : PR 2009;61(1):13-21.
2009: F Montecucco; François Mach
Common inflammatory mediators orchestrate pathophysiological processes in rheumatoid arthritis and atherosclerosis.
Rheumatology (Oxford, England) 2009;48(1):11-22.
2008: Fabrizio Montecucco; Sabine Steffens; Fabienne Burger; Graziano Pelli; Claudia Monaco; François Mach
C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes.
Journal of leukocyte biology 2008;84(4):1109-19.
2008: Patrick Saudan; Hajo Muller; Eric Feraille; Pierre-Yves Martin; François Mach
Renin-angiotensin system blockade and contrast-induced renal toxicity.
Journal of nephrology 2008;21(5):681-5.
2008: Nicolas Vuilleumier; Emmanuel Charbonney; Lionel Fontao; Montserrat Alvarez; Natacha Turck; jean-charles sanchez; Pierre R Burkhard; Noury Mensi; Marc Righini; Guido Reber; Richard James; François Mach; Jean-Claude Chevrolet; Jean-Michel Dayer; Johan Frostegard; Pascale Roux-Lombard
Anti-(apolipoprotein A-1) IgGs are associated with high levels of oxidized low-density lipoprotein in acute coronary syndrome.
Clinical science (London, England : 1979) 2008;115(1):25-33.
2008: Siv Fokstuen; Robert Lyle; Analia Munoz; Corinne Gehrig; René Lerch; Andreas Perrot; Karl Josef Osterziel; Christian Geier; Maurice Beghetti; François Mach; Juan Sztajzel; Ulrich Sigwart; Stylianos E Antonarakis; Jean-Louis Blouin
A DNA resequencing array for pathogenic mutation detection in hypertrophic cardiomyopathy.
Human mutation 2008;29(6):879-85.
2008: Vincent Braunersreuther; Sabine Steffens; Claire Arnaud; Graziano Pelli; Fabienne Burger; Amanda Proudfoot; François Mach
A novel RANTES antagonist prevents progression of established atherosclerotic lesions in mice.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(6):1090-6.
2008: François Mach; Sabine Steffens
The role of the endocannabinoid system in atherosclerosis.
Journal of neuroendocrinology 2008;20 Suppl 1():53-7.
2008: Tobias von Lukowicz; Paul O Hassa; Christine Lohmann; Jan Borén; Vincent Braunersreuther; François Mach; Bernhard Odermatt; Monika Gersbach; Giovanni G Camici; Barbara E Stähli; Felix C Tanner; Michael Hottiger; Thomas F Lüscher; Christian M Matter
PARP1 is required for adhesion molecule expression in atherogenesis.
Cardiovascular research 2008;78(1):158-66.
2008: Fabrizio Montecucco; Fabienne Burger; François Mach; Sabine Steffens
CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways.
American journal of physiology. Heart and circulatory physiology 2008;294(3):H1145-55.
2008: Sabine Steffens; François Mach
Adiponectin and adaptive immunity: linking the bridge from obesity to atherogenesis.
Circulation research 2008;102(2):140-2.
2008: Fabrizio Montecucco; François Mach
New evidences for C-reactive protein (CRP) deposits in the arterial intima as a cardiovascular risk factor.
Clinical interventions in aging 2008;3(2):341-9.
2008: Fabrizio Montecucco; Sabine Steffens; François Mach
Insulin resistance: a proinflammatory state mediated by lipid-induced signaling dysfunction and involved in atherosclerotic plaque instability.
Mediators of inflammation 2008;2008():767623.
2008: François Mach; F Montecucco; Sabine Steffens
Cannabinoid receptors in acute and chronic complications of atherosclerosis.
British journal of pharmacology 2008;153(2):290-8.
2008: Pierre Fontana; David Senouf; François Mach
Biological effect of increased maintenance dose of clopidogrel in cardiovascular outpatients and influence of the cytochrome P450 2C19*2 allele on clopidogrel responsiveness.
Thrombosis research 2008;121(4):463-8.
2007: René R S Packard; Susanna Schlegel; David Senouf; Fabienne Burger; Philippe Sigaud; Thomas Perneger; Claire-Anne Siegrist; François Mach
Atorvastatin treatment and vaccination efficacy.
Journal of clinical pharmacology 2007;47(8):1022-7.
2007: Vincent Braunersreuther; François Mach; Sabine Steffens
The specific role of chemokines in atherosclerosis.
Thrombosis and haemostasis 2007;97(5):714-21.
2007: Vincent Braunersreuther; Alma Zernecke; Claire Arnaud; Elisa A Liehn; Sabine Steffens; Erdenechimeg Shagdarsuren; Kiril Bidzhekov; Fabienne Burger; Graziano Pelli; Bruno Luckow; François Mach; Christian Weber
Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(2):373-9.
2007: Fabrizio Montecucco; Sabine Steffens; François Mach
The immune response is involved in atherosclerotic plaque calcification: could the RANKL/RANK/OPG system be a marker of plaque instability?
Clinical & developmental immunology 2007;2007():75805.
2007: Sylvie Dunoyer-Geindre; Brenda R Kwak; Graziano Pelli; Isabelle Roth; Nathalie Satta; Richard J Fish; Guido Reber; François Mach; Egbert Kruithof; Philippe de Moerloose
Immunization of LDL receptor-deficient mice with beta2-glycoprotein 1 or human serum albumin induces a more inflammatory phenotype in atherosclerotic plaques.
Thrombosis and haemostasis 2007;97(1):129-38.
2006: Sabine Steffens; Fabienne Burger; Graziano Pelli; Yann Dean; Greg Elson; Marie H Kosco-Vilbois; Lucienne Chatenoud; François Mach
Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice.
Circulation 2006;114(18):1977-84.
2006: Sabine Steffens; François Mach
Cannabinoid receptors in atherosclerosis.
Current opinion in lipidology 2006;17(5):519-26.
2006: Vincent Braunersreuther; François Mach
Leukocyte recruitment in atherosclerosis: potential targets for therapeutic approaches?
Cellular and molecular life sciences : CMLS 2006;63(18):2079-88.
2006: Niels R Veillard; Vincent Braunersreuther; Claire Arnaud; Fabienne Burger; Graziano Pelli; Sabine Steffens; François Mach
Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages.
Atherosclerosis 2006;188(1):51-8.
2006: Sabine Steffens; François Mach
Drug insight: Immunomodulatory effects of statins--potential benefits for renal patients?
Nature clinical practice. Nephrology 2006;2(7):378-87.
2006: François Mach
New anti-inflammatory agents to reduce atherosclerosis.
Archives of physiology and biochemistry 2006;112(2):130-7.
2006: Jean-Louis Frossard; Philippe Morel; Brenda R Kwak; Catherine Pastor; Thierry Berney; Léo Buhler; Alain Von Laufen; Sandrine Demulder; François Mach
Soluble CD40 ligand in prediction of acute severe pancreatitis.
World journal of gastroenterology : WJG 2006;12(10):1613-6.
2006: Sabine Steffens; François Mach
Towards a therapeutic use of selective CB2 cannabinoid receptor ligands for atherosclerosis.
Future cardiology 2006;2(1):49-53.
2006: Sabine Steffens; François Mach
[Toward a therapeutic use of cannabinoid CB(2) receptor in atherosclerosis].
Médecine sciences : M/S 2006;22(1):7-9.
2005: Thomas Christen; François Mach; Dominique Didier; Afksendiyos Kalangos; Vitali Verin; Pedro T Trindade
Late cardiac tamponade after percutaneous closure of a patent foramen ovale.
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2005;6(6):465-9.
2005: Niels R Veillard; Sabine Steffens; Graziano Pelli; B Lu; Brenda R Kwak; Craig Gerard; Israel F Charo; François Mach
Differential influence of chemokine receptors CCR2 and CXCR3 in development of atherosclerosis in vivo.
Circulation 2005;112(6):870-8.
2005: Claire Arnaud; Vincent Braunersreuther; François Mach
Toward immunomodulatory and anti-inflammatory properties of statins.
Trends in cardiovascular medicine 2005;15(6):202-6.
2005: C Arnaud; François Mach
Pleiotropic effects of statins in atherosclerosis: role on endothelial function, inflammation and immunomodulation.
Archives des maladies du coeur et des vaisseaux 2005;98(6):661-6.
2005: Faten Merhi-Soussi; Brenda R Kwak; David Magne; Christos Chadjichristos; Marina Berti; Graziano Pelli; Richard W James; François Mach; Cem Gabay
Interleukin-1 plays a major role in vascular inflammation and atherosclerosis in male apolipoprotein E-knockout mice.
Cardiovascular research 2005;66(3):583-93.
2005: Claire Arnaud; Fabienne Burger; Sabine Steffens; Niels R Veillard; Tuan Huy Nguyen; Didier Trono; François Mach
Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(6):1231-6.
2005: Siv Fokstuen; Jean-Louis Blouin; Robert Lyle; René Lerch; M Beghetti; François Mach; Juan Sztajzel; Stylianos E Antonarakis; U Sigwart
[The contribution of molecular genetics to clinical cardiology: the example of hypertrophic cardiomyopathy].
Revue médicale suisse 2005;1(21):1448, 1450, 1452-3.
2005: Sabine Steffens; Niels R Veillard; Claire Arnaud; Graziano Pelli; Fabienne Burger; Christian Staub; Meliha Karsak; Andreas Zimmer; Jean-Louis Frossard; François Mach
Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice.
Nature 2005;434(7034):782-6.
2005: Claire Arnaud; Niels R Veillard; François Mach
Cholesterol-independent effects of statins in inflammation, immunomodulation and atherosclerosis.
Current drug targets. Cardiovascular & haematological disorders 2005;5(2):127-34.
2004: Sabine Steffens; François Mach
Inflammation and atherosclerosis.
Herz 2004;29(8):741-8.
2004: Niels R Veillard; Sabine Steffens; Fabienne Burger; Graziano Pelli; François Mach
Differential expression patterns of proinflammatory and antiinflammatory mediators during atherogenesis in mice.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2339-44.
2004: Sabine Steffens; François Mach
Anti-inflammatory properties of statins.
Seminars in vascular medicine 2004;4(4):417-22.
2004: Catherine M Pastor; Jérôme Pugin; Brenda R Kwak; Marc Chanson; François Mach; Antoine Hadengue; Jean-Louis Frossard
Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia.
Critical care medicine 2004;32(8):1759-63.
2004: François Mach
Statins as immunomodulatory agents.
Circulation 2004;109(21 Suppl 1):II15-7.
2004: Niels R Veillard; Brenda R Kwak; Graziano Pelli; Flore Mulhaupt; Richard W James; Amanda E I Proudfoot; François Mach
Antagonism of RANTES receptors reduces atherosclerotic plaque formation in mice.
Circulation research 2004;94(2):253-61.
2003: Yordanka Dimitrova; Sylvie Dunoyer-Geindre; Guido Reber; François Mach; Egbert Kruithof; Philippe de Moerloose
Effects of statins on adhesion molecule expression in endothelial cells.
Journal of thrombosis and haemostasis : JTH 2003;1(11):2290-9.
2003: Patrick Saudan; François Mach; Thomas Perneger; Bruno Schnetzler; Catherine Stoermann; Zina Fumeaux; Michel Rossier; Pierre-Yves Martin
Safety of low-dose spironolactone administration in chronic haemodialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(11):2359-63.
2003: Brenda R Kwak; Flore Mulhaupt; François Mach
Atherosclerosis: anti-inflammatory and immunomodulatory activities of statins.
Autoimmunity reviews 2003;2(6):332-8.
2003: François Mach
Statins as novel immunomodulators: from cell to potential clinical benefit.
Thrombosis and haemostasis 2003;90(4):607-10.
2003: Flore Mulhaupt; Christian M Matter; Brenda R Kwak; Graziano Pelli; Niels R Veillard; Fabienne Burger; Pierre Graber; Thomas F Lüscher; François Mach
Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells.
Cardiovascular research 2003;59(3):755-66.
2003: Cindy W Wong; Fabienne Burger; Graziano Pelli; François Mach; Brenda R Kwak
Dual benefit of reduced Cx43 on atherosclerosis in LDL receptor-deficient mice.
Cell communication & adhesion 2003;10(4-6):395-400.
2003: Brenda R Kwak; Niels R Veillard; Graziano Pelli; Flore Mulhaupt; Richard W James; Marc Chanson; François Mach
Reduced connexin43 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice.
Circulation 2003;107(7):1033-9.
2002: François Mach
Toward a role for statins in immunomodulation.
Molecular interventions 2002;2(8):478-80.
2002: Niels R Veillard; François Mach
Statins: the new aspirin?
Cellular and molecular life sciences : CMLS 2002;59(11):1771-86.
2002: Stéphane Bosquet; Henri Sunthorn; Sina Zaim; René Lerch; François Mach
Right atrial thrombus formation after radiofrequency catheter ablation of a left-sided accessory pathway using a transseptal approach.
Pacing and clinical electrophysiology : PACE 2002;25(7):1146-8.
2002: François Mach
Statins as immunomodulators.
Transplant immunology 2002;9(2-4):197-200.
2002: Brenda R Kwak; Samir Myit; Flore Mulhaupt; Niels R Veillard; Nathalie Rufer; Eddy Roosnek; François Mach
PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells.
Circulation research 2002;90(3):356-62.
2002: Brenda R Kwak; Flore Mulhaupt; Niels R Veillard; Daniel Gros; François Mach
Altered pattern of vascular connexin expression in atherosclerotic plaques.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(2):225-30.
2001: Jean-Louis Frossard; Brenda R Kwak; Marc Chanson; Philippe Morel; Antoine Hadengue; François Mach
Cd40 ligand-deficient mice are protected against cerulein-induced acute pancreatitis and pancreatitis-associated lung injury.
Gastroenterology 2001;121(1):184-94.
2001: Brenda R Kwak; Flore Mulhaupt; Niels R Veillard; Graziano Pelli; François Mach
The HMG-CoA reductase inhibitor simvastatin inhibits IFN-gamma induced MHC class II expression in human vascular endothelial cells.
Swiss medical weekly 2001;131(3-4):41-6.
2000: Brenda R Kwak; Flore Mulhaupt; Samir Myit; François Mach
Statins as a newly recognized type of immunomodulator.
Nature medicine 2000;6(12):1399-402.