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Tina Machu

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TOP 3
Tina K Machu
Therapeutics of 5-HT3 receptor antagonists: current uses and future directions.
Mitesh Sanghvi; Ayman K Hamouda; Margaret I Davis; Russell A Morton; Shouryadeep Srivastava; Akash Pandhare; Phaneendra K Duddempudi; Tina K Machu; David M Lovinger; jonathan cohen; Michael P Blanton
Hydrophobic photolabeling studies identify the lipid-protein interface of the 5-HT3A receptor.
A N de Oliveira-Pierce; R Zhang; Tina K Machu
Colchicine: a novel positive allosteric modulator of the human 5-hydroxytryptamine3A receptor.

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All Publications

2011: Tina K Machu
Therapeutics of 5-HT3 receptor antagonists: current uses and future directions.
Pharmacology & therapeutics 2011;130(3):338-47.
2009: Mitesh Sanghvi; Ayman K Hamouda; Margaret I Davis; Russell A Morton; Shouryadeep Srivastava; Akash Pandhare; Phaneendra K Duddempudi; Tina K Machu; David M Lovinger; jonathan cohen; Michael P Blanton
Hydrophobic photolabeling studies identify the lipid-protein interface of the 5-HT3A receptor.
Biochemistry 2009;48(39):9278-86.
2009: A N de Oliveira-Pierce; R Zhang; Tina K Machu
Colchicine: a novel positive allosteric modulator of the human 5-hydroxytryptamine3A receptor.
The Journal of pharmacology and experimental therapeutics 2009;329(2):838-47.
2007: Ran Zhang; Xiaofei Wen; Julius D Militante; Brent Hester; Heather E Rhubottom; Hongwei Sun; Nancy J Leidenheimer; Dong Yan; Michael M White; Tina K Machu
The role of loop F residues in determining differential d-tubocurarine potencies in mouse and human 5-hydroxytryptamine 3A receptors.
Biochemistry 2007;46(5):1194-204.
2006: Ran Zhang; Natalie A White; Ferenc Soti; William R Kem; Tina K Machu
N-terminal domains in mouse and human 5-hydroxytryptamine3A receptors confer partial agonist and antagonist properties to benzylidene analogs of anabaseine.
The Journal of pharmacology and experimental therapeutics 2006;317(3):1276-84.
2006: Tina K Machu; Glenn H Dillon; RenQi Huang; David M Lovinger; Nancy J Leidenheimer
Temperature: an important experimental variable in studying PKC modulation of ligand-gated ion channels.
Brain research 2006;1086(1):1-8.
2006: Xiang-Qun Hu; Volodya Hayrapetyan; Jay J Gadhiya; Heather E Rhubottom; David M Lovinger; Tina K Machu
Mutations of L293 in transmembrane two of the mouse 5-hydroxytryptamine3A receptor alter gating and alcohol modulatory actions.
British journal of pharmacology 2006;148(1):88-101.
2006: Ayman K Hamouda; Mitesh Sanghvi; Daniel Sauls; Tina K Machu; Michael P Blanton
Assessing the lipid requirements of the Torpedo californica nicotinic acetylcholine receptor.
Biochemistry 2006;45(13):4327-37.
2006: Daryl L Davies; Liana Asatryan; Sacha T Kuo; John J Woodward; Brian F King; Ronald L Alkana; Cheng Xiao; Jiang Hong Ye; Hui Sun; Li Zhang; Xiang-Qun Hu; Volodya Hayrapetyan; David M Lovinger; Tina K Machu
Effects of ethanol on adenosine 5'-triphosphate-gated purinergic and 5-hydroxytryptamine receptors.
Alcoholism, clinical and experimental research 2006;30(2):349-58.
2005: Volodya Hayrapetyan; Monica Jenschke; Glenn H Dillon; Tina K Machu
Co-expression of the 5-HT(3B) subunit with the 5-HT(3A) receptor reduces alcohol sensitivity.
Brain research. Molecular brain research 2005;142(2):146-50.
2004: William J McBride; David M Lovinger; Tina K Machu; Richard J Thielen; Zachary A Rodd; James M Murphy; John D Roache; Bankole A Johnson
Serotonin-3 receptors in the actions of alcohol, alcohol reinforcement, and alcoholism.
Alcoholism, clinical and experimental research 2004;28(2):257-67.
2003: J S Sessoms-Sikes; Margaret E Hamilton; Li-Xin Liu; David M Lovinger; Tina K Machu
A mutation in transmembrane domain II of the 5-hydroxytryptamine(3A) receptor stabilizes channel opening and alters alcohol modulatory actions.
The Journal of pharmacology and experimental therapeutics 2003;306(2):595-604.
2003: Paromita Das; Cathy Lynne Bell-Horner; Tina K Machu; Glenn H Dillon
The GABA(A) receptor antagonist picrotoxin inhibits 5-hydroxytryptamine type 3A receptors.
Neuropharmacology 2003;44(4):431-8.
2002: Daryl L Davies; Tina K Machu; Yumei Guo; Ronald L Alkana
Ethanol sensitivity in ATP-gated P2X receptors is subunit dependent.
Alcoholism, clinical and experimental research 2002;26(6):773-8.
2002: Thomas L Freeman; Geoffrey M Thiele; Dean J Tuma; Tina K Machu; Mark E Mailliard
ATA2-mediated amino acid uptake following partial hepatectomy is regulated by redistribution to the plasma membrane.
Archives of biochemistry and biophysics 2002;400(2):215-22.
2002: Steven J Coultrap; Tina K Machu
Enhancement of 5-hydroxytryptamine3A receptor function by phorbol 12-myristate, 13-acetate is mediated by protein kinase C and tyrosine kinase activity.
Receptors & channels 2002;8(2):63-70.
2001: Tina K Machu; Margaret E Hamilton; T F Frye; C L Shanklin; M C Harris; H Sun; Thomas E Tenner; Ferenc Soti; William R Kem
Benzylidene analogs of anabaseine display partial agonist and antagonist properties at the mouse 5-hydroxytryptamine(3A) receptor.
The Journal of pharmacology and experimental therapeutics 2001;299(3):1112-9.
2000: H Sun; Tina K Machu
Bicuculline antagonizes 5-HT(3A) and alpha2 glycine receptors expressed in Xenopus oocytes.
European journal of pharmacology 2000;391(3):243-9.
1999: H Sun; Elizabeth A McCardy; Tina K Machu; Michael P Blanton
Characterization of interaction of 3,4,5-trimethoxybenzoic acid 8-(diethylamino)octyl ester with Torpedo californica nicotinic acetylcholine receptor and 5-hydroxytryptamine3 receptor.
The Journal of pharmacology and experimental therapeutics 1999;290(1):129-35.
1999: Steven J Coultrap; H Sun; Thomas E Tenner; Tina K Machu
Competitive antagonism of the mouse 5-hydroxytryptamine3 receptor by bisindolylmaleimide I, a "selective" protein kinase C inhibitor.
The Journal of pharmacology and experimental therapeutics 1999;290(1):76-82.
1999: Tina K Machu; Steven J Coultrap; M D Waugh; Margaret E Hamilton
Mutation of putative phosphorylation sites in the 5-hydroxytryptamine3 receptor does not eliminate its modulation by ethanol.
Alcoholism, clinical and experimental research 1999;23(1):12-7.
1998: Richard Chapell; J Martin; Tina K Machu; Nancy J Leidenheimer
Direct channel-gating and modulatory effects of triiodothyronine on recombinant GABA(A) receptors.
European journal of pharmacology 1998;349(1):115-21.
1998: Tina K Machu
Colchicine competitively antagonizes glycine receptors expressed in Xenopus oocytes.
Neuropharmacology 1998;37(3):391-6.
1998: Tina K Machu; S J Mihic; J E Dildy-Mayfield
Selective actions of a detergent on ligand-gated ion channels expressed in Xenopus oocytes.
The Journal of pharmacology and experimental therapeutics 1998;284(1):32-6.
1995: R Adron Harris; S John Mihic; J E Dildy-Mayfield; Tina K Machu
Actions of anesthetics on ligand-gated ion channels: role of receptor subunit composition.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(14):1454-62.
1992: J E Dildy-Mayfield; Tina K Machu; Steven W Leslie
Ethanol and voltage- or receptor-mediated increases in cytosolic Ca2+ in brain cells.
Alcohol (Fayetteville, N.Y.) 1992;9(1):63-9.
1990: John J Woodward; Tina K Machu; Steven W Leslie
Chronic ethanol treatment alters omega-conotoxin and Bay K 8644 sensitive calcium channels in rat striatal synaptosomes.
Alcohol (Fayetteville, N.Y.) 1990;7(4):279-84.
1989: Tina K Machu; John J Woodward; Steven W Leslie
Ethanol and inositol 1,4,5-trisphosphate mobilize calcium from rat brain microsomes.
Alcohol (Fayetteville, N.Y.) 1989;6(6):431-6.
1988: A A Welder; Tina K Machu; S W Leslie; R E Wilcox; J Bradlaw; D Acosta
Beta-adrenergic receptor characteristics of postnatal rat myocardial cell preparations.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1988;24(8):771-7.