Jaroslaw Maciejewski

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TOP 3
Ye Ying; McDevitt Michael A; Guo Mingzhou; Zhang Wei; Galm Oliver; Gore Steven D; Karp Judith E; Maciejewski Jaroslaw P; Kowalski Jeanne; Tsai Hua-Ling; Gondek Lukasz P; Tsai Hsing-Chen; Wang Xiaofei; Hooker Craig; Smith B Douglas; Carraway Hetty E; Herman James G
Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies.
Tiu Ramon V; Gondek Lukasz P; O'Keefe Christine L; Huh Jungwon; Sekeres Mikkael A; Elson Paul; McDevitt Michael A; Wang Xiao Fei; Levis Mark J; Karp Judith E; Advani Anjali S; Maciejewski Jaroslaw P
New lesions detected by single nucleotide polymorphism array-based chromosomal analysis have important clinical impact in acute myeloid leukemia.
Mohan Sanjay R; Clemente Michael J; Afable Manuel; Cazzolli Heather N; Bejanyan Nelli; Wlodarski Marcin W; Lichtin Alan E; Maciejewski Jaroslaw P
Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8+ large granular lymphocyte leukemia.

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2009: Ye Ying; McDevitt Michael A; Guo Mingzhou; Zhang Wei; Galm Oliver; Gore Steven D; Karp Judith E; Maciejewski Jaroslaw P; Kowalski Jeanne; Tsai Hua-Ling; Gondek Lukasz P; Tsai Hsing-Chen; Wang Xiaofei; Hooker Craig; Smith B Douglas; Carraway Hetty E; Herman James G
Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies.
Cancer research 2009;69(21):8482-90.
2009: Tiu Ramon V; Gondek Lukasz P; O'Keefe Christine L; Huh Jungwon; Sekeres Mikkael A; Elson Paul; McDevitt Michael A; Wang Xiao Fei; Levis Mark J; Karp Judith E; Advani Anjali S; Maciejewski Jaroslaw P
New lesions detected by single nucleotide polymorphism array-based chromosomal analysis have important clinical impact in acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(31):5219-26.
2009: Mohan Sanjay R; Clemente Michael J; Afable Manuel; Cazzolli Heather N; Bejanyan Nelli; Wlodarski Marcin W; Lichtin Alan E; Maciejewski Jaroslaw P
Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8+ large granular lymphocyte leukemia.
Haematologica 2009;94(10):1407-14.
2009: Maciejewski Jaroslaw P; Tiu Ramon V; O'Keefe Christine
Application of array-based whole genome scanning technologies as a cytogenetic tool in haematological malignancies.
British journal of haematology 2009;146(5):479-88.
2009: Jankowska Anna M; Szpurka Hadrian; Tiu Ramon V; Makishima Hideki; Afable Manuel; Huh Jungwon; O'Keefe Christine L; Ganetzky Rebecca; McDevitt Michael A; Maciejewski Jaroslaw P
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms.
Blood 2009;113(25):6403-10.
2009: Jiang Ying; Dunbar Andrew; Gondek Lukasz P; Mohan Sanjay; Rataul Manjot; O'Keefe Christine; Sekeres Mikkael; Saunthararajah Yogen; Maciejewski Jaroslaw P
Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.
Blood 2009;113(6):1315-25.
2009: Babel Nina; Brestrich Gordon; Gondek Lukasz P; Sattler Arne; Wlodarski Marcin W; Poliak Nina; Bethke Nicole; Thiel Andreas; Hammer Markus H; Reinke Petra; Maciejewski Jaroslaw P
Clonotype analysis of cytomegalovirus-specific cytotoxic T lymphocytes.
Journal of the American Society of Nephrology : JASN 2009;20(2):344-52.
2009: Mohan Sanjay R; Maciejewski Jaroslaw P
Diagnosis and therapy of neutropenia in large granular lymphocyte leukemia.
Current opinion in hematology 2009;16(1):27-34.
2008: Haferlach Claudia; Bacher Ulrike; Tiu Ramon; Maciejewski Jaroslaw P; List Alan
Myelodysplastic syndromes with del(5q): indications and strategies for cytogenetic testing.
Cancer genetics and cytogenetics 2008;187(2):101-11.
2008: Sekeres Mikkael A; Schoonen W Marieke; Kantarjian Hagop; List Alan; Fryzek Jon; Paquette Ronald; Maciejewski Jaroslaw P
Characteristics of US patients with myelodysplastic syndromes: results of six cross-sectional physician surveys.
Journal of the National Cancer Institute 2008;100(21):1542-51.
2008: Subbiah Vivek; Viny Aaron D; Rosenblatt Steven; Pohlman Brad; Lichtin Alan; Maciejewski Jaroslaw P
Outcomes of splenectomy in T-cell large granular lymphocyte leukemia with splenomegaly and cytopenia.
Experimental hematology 2008;36(9):1078-83.
2008: Maciejewski Jaroslaw P; Mufti Ghulam J
Whole genome scanning as a cytogenetic tool in hematologic malignancies.
Blood 2008;112(4):965-74.
2008: Szpurka Hadrian; Schade Andrew E; Jankowska Anna M; Maciejewski Jaroslaw P
Altered lipid raft composition and defective cell death signal transduction in glycosylphosphatidylinositol anchor-deficient PIG-A mutant cells.
British journal of haematology 2008;142(3):413-22.
2008: Gibson Sarah E; Schade Andrew E; Szpurka Hadrian; Bak Beata; Maciejewski Jaroslaw P; Hsi Eric D
Phospho-STAT5 expression pattern with the MPL W515L mutation is similar to that seen in chronic myeloproliferative disorders with JAK2 V617F.
Human pathology 2008;39(7):1111-4.
2008: Lai Dominic W; Loughran Thomas P; Maciejewski Jaroslaw P; Sasu Sebastian; Song Sophie X; Epling-Burnette P K; Paquette Ronald L
Acquired amegakaryocytic thrombocytopenia and pure red cell aplasia associated with an occult large granular lymphocyte leukemia.
Leukemia research 2008;32(5):823-7.
2008: McIver Z; Serio B; Dunbar A; O'Keefe C L; Powers J; Wlodarski M; Jin T; Sobecks R; Bolwell B; Maciejewski J P
Double-negative regulatory T cells induce allotolerance when expanded after allogeneic haematopoietic stem cell transplantation.
British journal of haematology 2008;141(2):170-8.
2008: Sobecks R M; Ball E J; Askar M; Theil K S; Rybicki L A; Thomas D; Brown S; Kalaycio M; Andresen S; Pohlman B; Dean R; Sweetenham J; Macklis R; Bernhard L; Cherni K; Copelan E; Maciejewski J P; Bolwell B J
Influence of killer immunoglobulin-like receptor/HLA ligand matching on achievement of T-cell complete donor chimerism in related donor nonmyeloablative allogeneic hematopoietic stem cell transplantation.
Bone marrow transplantation 2008;41(8):709-14.
2008: Wlodarski Marcin Wojciech; Nearman Zachary; Jiang Ying; Lichtin Alan; Maciejewski Jaroslaw Pawel
Clonal predominance of CD8(+) T cells in patients with unexplained neutropenia.
Experimental hematology 2008;36(3):293-300.
2008: Wlodarski Marcin W; Nearman Zachary; Jankowska Anna; Babel Nina; Powers Jennifer; Leahy Patrick; Volk Hans-Dieter; Maciejewski Jaroslaw P
Phenotypic differences between healthy effector CTL and leukemic LGL cells support the notion of antigen-triggered clonal transformation in T-LGL leukemia.
Journal of leukocyte biology 2008;83(3):589-601.
2008: Jankowska A M; Gondek L P; Szpurka H; Nearman Z P; Tiu R V; Maciejewski J P
Base excision repair dysfunction in a subgroup of patients with myelodysplastic syndrome.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(3):551-8.
2008: Brodsky Robert A; Young Neal S; Antonioli Elisabetta; Risitano Antonio M; Schrezenmeier Hubert; Schubert Jörg; Gaya Anna; Coyle Luke; de Castro Carlos; Fu Chieh-Lin; Maciejewski Jaroslaw P; Bessler Monica; Kroon Henk-André; Rother Russell P; Hillmen Peter
Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.
Blood 2008;111(4):1840-7.
2008: Schade Andrew E; Schieven Gary L; Townsend Robert; Jankowska Anna M; Susulic Vojkan; Zhang Rosemary; Szpurka Hadrian; Maciejewski Jaroslaw P
Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation.
Blood 2008;111(3):1366-77.
2008: Gondek Lukasz P; Tiu Ramon; O'Keefe Christine L; Sekeres Mikkael A; Theil Karl S; Maciejewski Jaroslaw P
Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML.
Blood 2008;111(3):1534-42.
2008: Haddad A S; Subbiah V; Lichtin A E; Theil K S; Maciejewski J P
Hypocupremia and bone marrow failure.
Haematologica 2008;93(1):e1-5.
2007: Nearman Zachary P; Szpurka Hadrian; Serio Bianca; Warshawksy Ilka; Theil Karl; Lichtin Alan; Sekeres Mikkael A; Maciejewski Jaroslaw P
Hemochromatosis-associated gene mutations in patients with myelodysplastic syndromes with refractory anemia with ringed sideroblasts.
American journal of hematology 2007;82(12):1076-9.
2007: Gondek Lukasz P; Haddad Abdo S; O'Keefe Christine L; Tiu Ramon; Wlodarski Marcin W; Sekeres Mikkael A; Theil Karl S; Maciejewski Jaroslaw P
Detection of cryptic chromosomal lesions including acquired segmental uniparental disomy in advanced and low-risk myelodysplastic syndromes.
Experimental hematology 2007;35(11):1728-38.
2007: Gondek L P; Tiu R; Haddad A S; O'Keefe C L; Sekeres M A; Theil K S; Maciejewski J P
Single nucleotide polymorphism arrays complement metaphase cytogenetics in detection of new chromosomal lesions in MDS.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(9):2058-61.
2007: O'Keefe Christine L; Gondek Lukasz; Davis Randall; Kuczkowski Elizabeth; Sobecks Ronald M; Rodriguez Alexander; Narvaez Yadira; McIver Zachariah; Tuthill Ralph; Laughlin Mary; Bolwell Brian; Maciejewski Jaroslaw P
Molecular analysis of alloreactive CTL post-hemopoietic stem cell transplantation.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):2013-22.
2007: Tiu R; Gondek L; O'Keefe C; Maciejewski J P
Clonality of the stem cell compartment during evolution of myelodysplastic syndromes and other bone marrow failure syndromes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(8):1648-57.
2007: Kordasti Shahram Y; Ingram Wendy; Hayden Janet; Darling David; Barber Linda; Afzali Behdad; Lombardi Giovanna; Wlodarski Marcin W; Maciejewski Jaroslaw P; Farzaneh Farzin; Mufti Ghulam J
CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS).
Blood 2007;110(3):847-50.
2007: Sobecks R M; Ball E J; Maciejewski J P; Rybicki L A; Brown S; Kalaycio M; Pohlman B; Andresen S; Theil K S; Dean R; Bolwell B J
Survival of AML patients receiving HLA-matched sibling donor allogeneic bone marrow transplantation correlates with HLA-Cw ligand groups for killer immunoglobulin-like receptors.
Bone marrow transplantation 2007;39(7):417-24.
2007: Sekeres Mikkael A; Fu Alex Z; Maciejewski Jaroslaw P; Golshayan Ali-Reza; Kalaycio Matt E; Kattan Michael W
A Decision analysis to determine the appropriate treatment for low-risk myelodysplastic syndromes.
Cancer 2007;109(6):1125-32.
2007: O'Keefe Christine L; Tiu Ramon; Gondek Lukasz P; Powers Jennifer; Theil Karl S; Kalaycio Matt; Lichtin Alan; Sekeres Mikkael A; Maciejewski Jaroslaw P
High-resolution genomic arrays facilitate detection of novel cryptic chromosomal lesions in myelodysplastic syndromes.
Experimental hematology 2007;35(2):240-51.
2007: Aboudola Samer; Murugesan Guruanthan; Szpurka Hadrian; Ramsingh Giri; Zhao Xiaoxian; Prescott Nichole; Tubbs Raymond R; Maciejewski Jaroslaw P; Hsi Eric D
Bone marrow phospho-STAT5 expression in non-CML chronic myeloproliferative disorders correlates with JAK2 V617F mutation and provides evidence of in vivo JAK2 activation.
The American journal of surgical pathology 2007;31(2):233-9.
2007: Risitano Antonio M; Maciejewski Jaroslaw P; Selleri Carmine; Rotoli Bruno
Function and malfunction of hematopoietic stem cells in primary bone marrow failure syndromes.
Current stem cell research & therapy 2007;2(1):39-52.
2007: Nearman Zachary P; Wlodarski Marcin; Jankowska Anna M; Howe Evan; Narvaez Yadira; Ball Edward; Maciejewski Jaroslaw P
Immunogenetic factors determining the evolution of T-cell large granular lymphocyte leukaemia and associated cytopenias.
British journal of haematology 2007;136(2):237-48.
2007: Gondek Lukasz P; Dunbar Andrew J; Szpurka Hadrian; McDevitt Michael A; Maciejewski Jaroslaw P
SNP array karyotyping allows for the detection of uniparental disomy and cryptic chromosomal abnormalities in MDS/MPD-U and MPD.
PloS one 2007;2(11):e1225.
2007: Maciejewski Jaroslaw P; O'Keefe Christine; Gondek Lukasz; Tiu Ramon
Immune-mediated bone marrow failure syndromes of progenitor and stem cells: molecular analysis of cytotoxic T cell clones.
Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 2007;45(1):5-14.
2006: Schade Andrew E; Wlodarski Marcin W; Maciejewski Jaroslaw P
Pathophysiology defined by altered signal transduction pathways: the role of JAK-STAT and PI3K signaling in leukemic large granular lymphocytes.
Cell cycle (Georgetown, Tex.) 2006;5(22):2571-4.
2006: Szpurka Hadrian; Tiu Ramon; Murugesan Gurunathan; Aboudola Samer; Hsi Eric D; Theil Karl S; Sekeres Mikkael A; Maciejewski Jaroslaw P
Refractory anemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T), another myeloproliferative condition characterized by JAK2 V617F mutation.
Blood 2006;108(7):2173-81.
2006: Wlodarski Marcin W; Gondek Lukasz P; Nearman Zachary P; Plasilova Magdalena; Kalaycio Matt; Hsi Eric D; Maciejewski Jaroslaw P
Molecular strategies for detection and quantitation of clonal cytotoxic T-cell responses in aplastic anemia and myelodysplastic syndrome.
Blood 2006;108(8):2632-41.
2006: Wlodarski Marcin W; Schade Andrew E; Maciejewski Jaroslaw P
T-large granular lymphocyte leukemia: current molecular concepts.
Hematology (Amsterdam, Netherlands) 2006;11(4):245-56.
2006: Schade Andrew E; Powers Jennifer J; Wlodarski Marcin W; Maciejewski Jaroslaw P
Phosphatidylinositol-3-phosphate kinase pathway activation protects leukemic large granular lymphocytes from undergoing homeostatic apoptosis.
Blood 2006;107(12):4834-40.
2006: Murugesan Gurunathan; Aboudola Samer; Szpurka Hadrian; Verbic Mary Ann; Maciejewski Jaroslaw P; Tubbs Raymond R; Hsi Eric D
Identification of the JAK2 V617F mutation in chronic myeloproliferative disorders using FRET probes and melting curve analysis.
American journal of clinical pathology 2006;125(4):625-33.
2006: Zeng Weihua; Miyazato Akira; Chen Guibin; Kajigaya Sachiko; Young Neal S; Maciejewski Jaroslaw P
Interferon-gamma-induced gene expression in CD34 cells: identification of pathologic cytokine-specific signature profiles.
Blood 2006;107(1):167-75.
2005: Omine Mitsuhiro; Kinoshita Taroh; Nakakuma Hideki; Maciejewski Jaroslaw P; Parker Charles J; Socié Gérard
Paroxysmal nocturnal hemoglobinuria.
International journal of hematology 2005;82(5):417-21.
2005: Howe Evan C; Wlodarski Marcin; Ball Edward J; Rybicki Lisa; Maciejewski Jaroslaw P
Killer immunoglobulin-like receptor genotype in immune-mediated bone marrow failure syndromes.
Experimental hematology 2005;33(11):1357-62.
2005: Wlodarski Marcin W; O'Keefe Christine; Howe Evan C; Risitano Antonio M; Rodriguez Alexander; Warshawsky Ilka; Loughran Thomas P; Maciejewski Jaroslaw P
Pathologic clonal cytotoxic T-cell responses: nonrandom nature of the T-cell-receptor restriction in large granular lymphocyte leukemia.
Blood 2005;106(8):2769-80.
2005: Beck Rose C; Wlodarski Marcin; Gondek Lukasz; Theil Karl S; Tuthill Ralph J; Sobeck Ronald; Bolwell Brian; Maciejewski Jaroslaw P
Efficient identification of T-cell clones associated with graft-versus-host disease in target tissue allows for subsequent detection in peripheral blood.
British journal of haematology 2005;129(3):411-9.
2005: Chen G; Zeng W; Maciejewski J P; Kcyvanfar K; Billings E M; Young N S
Differential gene expression in hematopoietic progenitors from paroxysmal nocturnal hemoglobinuria patients reveals an apoptosis/immune response in 'normal' phenotype cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(5):862-8.
2005: Risitano A M; Maciejewski J P; Muranski P; Wlodarski M; O'Keefe C; Sloand E M; Young N S
Large granular lymphocyte (LGL)-like clonal expansions in paroxysmal nocturnal hemoglobinuria (PNH) patients.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(2):217-22.
2005: Maciejewski Jaroslaw P; Risitano Antonio M
Aplastic anemia: management of adult patients.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2005;():110-7.
2004: Chen Guibin; Zeng Weihua; Miyazato Akira; Billings Eric; Maciejewski Jaroslaw P; Kajigaya Sachiko; Sloand Elaine M; Young Neal S
Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities.
Blood 2004;104(13):4210-8.
2004: O'keefe Christine L; Sobecks Ronald M; Wlodarski Mercin; Rodriguez Alexander; Bell Kimberly; Kuczkowski Elizabeth; Bolwell Brian J; Maciejewski Jaroslaw P
Molecular TCR diagnostics can be used to identify shared clonotypes after allogeneic hematopoietic stem cell transplantation.
Experimental hematology 2004;32(10):1010-22.
2004: Kim Julian A; Rao Poornima; Graor Hallie; Rothchild Kevin; O'keefe Christine; Maciejewski Jaroslaw P
CDR3 spectratyping identifies clonal expansion within T-cell subpopulations that demonstrate therapeutic antitumor activity.
Surgery 2004;136(2):295-302.
2004: Khaiboullina Svetlana F; Maciejewski Jaroslaw P; Crapnell Kirsten; Spallone Patricia A; Dean Stock A; Pari Gregory S; Zanjani Esmail D; Jeor Stephen St
Human cytomegalovirus persists in myeloid progenitors and is passed to the myeloid progeny in a latent form.
British journal of haematology 2004;126(3):410-7.
2004: Risitano Antonio M; Maciejewski Jaroslaw P; Green Spencer; Plasilova Magdalena; Zeng Weihua; Young Neal S
In-vivo dominant immune responses in aplastic anaemia: molecular tracking of putatively pathogenetic T-cell clones by TCR beta-CDR3 sequencing.
Lancet 2004;364(9431):355-64.
2004: Kearns William G; Sutton Joanne F; Maciejewski Jaroslaw P; Young Neal S; Liu Johnson M
Genomic instability in bone marrow failure syndromes.
American journal of hematology 2004;76(3):220-4.
2004: O'Keefe Christine L; Risitano Antonio M; Maciejewski Jaroslaw P
Clinical implications of T cell receptor repertoire analysis after allogeneic stem cell transplantation.
Hematology (Amsterdam, Netherlands) 2004;9(3):189-98.
2004: Maciejewski Jaroslaw P; Selleri Carmine
Evolution of clonal cytogenetic abnormalities in aplastic anemia.
Leukemia & lymphoma 2004;45(3):433-40.
2004: O'Keefe Christine L; Plasilova Magdalena; Wlodarski Marcin; Risitano Antonio M; Rodriguez Alexander R; Howe Evan; Young Neal S; Hsi Eric; Maciejewski Jaroslaw P
Molecular analysis of TCR clonotypes in LGL: a clonal model for polyclonal responses.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1960-9.
2004: Chen Guibin; Kook Hoon; Zeng Weihua; Young Neal S; Maciejewski Jaroslaw P
Is there a direct effect of antithymocyte globulin on hematopoiesis?
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5(3):255-61.
2003: Maciejewski Jaroslaw P; Risitano Antonio
Hematopoietic stem cells in aplastic anemia.
Archives of medical research 2003;34(6):520-7.
2003: Beck Rose C; Stahl Steve; O'Keefe Christine L; Maciejewski Jaroslaw P; Theil Karl S; Hsi Eric D
Detection of mature T-cell leukemias by flow cytometry using anti-T-cell receptor V beta antibodies.
American journal of clinical pathology 2003;120(5):785-94.
2003: Maciejewski Jaroslaw P; Sloand Elaine M; Nunez Olga; Boss Carol; Young Neal S
Recombinant humanized anti-IL-2 receptor antibody (daclizumab) produces responses in patients with moderate aplastic anemia.
Blood 2003;102(10):3584-6.
2003: Selleri Carmine; Maciejewski Jaroslaw P; Montuori Nunzia; Ricci Patrizia; Visconte Valeria; Serio Bianca; Luciano Luigiana; Rotoli Bruno
Involvement of nitric oxide in farnesyltransferase inhibitor-mediated apoptosis in chronic myeloid leukemia cells.
Blood 2003;102(4):1490-8.
2003: Plasilova Magdalena; Risitano Antonio; Maciejewski Jaroslaw P
Application of the molecular analysis of the T-cell receptor repertoire in the study of immune-mediated hematologic diseases.
Hematology (Amsterdam, Netherlands) 2003;8(3):173-81.
2003: Risitano Antonio M; Holada Karel; Chen Guibin; Simak Jan; Vostal Jaroslav G; Young Neal S; Maciejewski Jaroslaw P
CD34+ cells from paroxysmal nocturnal hemoglobinuria (PNH) patients are deficient in surface expression of cellular prion protein (PrPc).
Experimental hematology 2003;31(1):65-72.
2002: Zeng Weihua; Maciejewski Jaroslaw P; Chen Guibin; Risitano Antonio M; Kirby Martha; Kajigaya Sachiko; Young Neal S
Selective reduction of natural killer T cells in the bone marrow of aplastic anaemia.
British journal of haematology 2002;119(3):803-9.
2002: Sloand Elaine M; Kim Sonnie; Fuhrer Monika; Risitano Antonio M; Nakamura Ryotaro; Maciejewski Jaroslaw P; Barrett A John; Young Neal S
Fas-mediated apoptosis is important in regulating cell replication and death in trisomy 8 hematopoietic cells but not in cells with other cytogenetic abnormalities.
Blood 2002;100(13):4427-32.
2002: Tisdale John F; Maciejewski Jaroslaw P; Nuñez Olga; Rosenfeld Stephen J; Young Neal S
Late complications following treatment for severe aplastic anemia (SAA) with high-dose cyclophosphamide (Cy): follow-up of a randomized trial.
Blood 2002;100(13):4668-70.
2002: Selleri Carmine; Maciejewski Jaroslaw P; Catalano Lucio; Ricci Patrizia; Andretta Claudia; Luciano Luigiana; Rotoli Bruno
Effects of cyclosporine on hematopoietic and immune functions in patients with hypoplastic myelodysplasia: in vitro and in vivo studies.
Cancer 2002;95(9):1911-22.
2002: Saunthararajah Yogen; Nakamura Ryotaro; Nam Jun-Mo; Robyn Jamie; Loberiza Fausto; Maciejewski Jaroslaw P; Simonis Toni; Molldrem Jeffrey; Young Neal S; Barrett A John
HLA-DR15 (DR2) is overrepresented in myelodysplastic syndrome and aplastic anemia and predicts a response to immunosuppression in myelodysplastic syndrome.
Blood 2002;100(5):1570-4.
2002: Young Neal S; Maciejewski Jaroslaw P; Sloand Elaine; Chen Guiben; Zeng Weihua; Risitano Antonio; Miyazato Akira
The relationship of aplastic anemia and PNH.
International journal of hematology 2002;76 Suppl 2():168-72.
2002: Maciejewski Jaroslaw P; Risitano Antonio; Kook Hoon; Zeng Weihua; Chen Guibin; Young Neal S
Immune pathophysiology of aplastic anemia.
International journal of hematology 2002;76 Suppl 1():207-14.
2002: Sloand Elaine; Kim Sonnie; Maciejewski Jaroslaw P; Tisdale John; Follmann Dean; Young Neal S
Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia.
Blood 2002;100(4):1185-91.
2002: Chen Guibin; Kirby Martha; Zeng Weihua; Young Neal S; Maciejewski Jaroslaw P
Superior growth of glycophosphatidy linositol-anchored protein-deficient progenitor cells in vitro is due to the higher apoptotic rate of progenitors with normal phenotype in vivo.
Experimental hematology 2002;30(7):774-82.
2002: Risitano Antonio M; Kook Hoon; Zeng Weihua; Chen Guibin; Young Neal S; Maciejewski Jaroslaw P
Oligoclonal and polyclonal CD4 and CD8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobinuria measured by V beta CDR3 spectratyping and flow cytometry.
Blood 2002;100(1):178-83.
2002: Kook Hoon; Risitano Antonio M; Zeng Weihua; Wlodarski Marcin; Lottemann Craig; Nakamura Ryotaro; Barrett John; Young Neal S; Maciejewski Jaroslaw P
Changes in T-cell receptor VB repertoire in aplastic anemia: effects of different immunosuppressive regimens.
Blood 2002;99(10):3668-75.
2002: Maciejewski Jaroslaw P; Risitano Antonio; Sloand Elaine M; Nunez Olga; Young Neal S
Distinct clinical outcomes for cytogenetic abnormalities evolving from aplastic anemia.
Blood 2002;99(9):3129-35.
2002: Maciejewski Jaroslaw P; Risitano Antonio M; Sloand Elaine M; Wisch Laura; Geller Nancy; Barrett John A; Young Neal S;
A pilot study of the recombinant soluble human tumour necrosis factor receptor (p75)-Fc fusion protein in patients with myelodysplastic syndrome.
British journal of haematology 2002;117(1):119-26.
2001: Maciejewski J P; Follmann D; Nakamura R; Saunthararajah Y; Rivera C E; Simonis T; Brown K E; Barrett J A; Young N S
Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome.
Blood 2001;98(13):3513-9.
2001: Kook H; Zeng W; Guibin C; Kirby M; Young N S; Maciejewski J P
Increased cytotoxic T cells with effector phenotype in aplastic anemia and myelodysplasia.
Experimental hematology 2001;29(11):1270-7.
2001: Zeng W; Maciejewski J P; Chen G; Young N S
Limited heterogeneity of T cell receptor BV usage in aplastic anemia.
The Journal of clinical investigation 2001;108(5):765-73.
2000: Maciejewski J P; Kim S; Sloand E; Selleri C; Young N S
Sustained long-term hematologic recovery despite a marked quantitative defect in the stem cell compartment of patients with aplastic anemia after immunosuppressive therapy.
American journal of hematology 2000;65(2):123-31.
2000: Young N S; Maciejewski J P
Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes "Why? Why? Why?".
The Journal of clinical investigation 2000;106(5):637-41.
2000: Selleri C; Maciejewski J P
The role of FAS-mediated apoptosis in chronic myelogenous leukemia.
Leukemia & lymphoma 2000;37(3-4):283-97.
2000: Sloand E M; Kim S; Maciejewski J P; Van Rhee F; Chaudhuri A; Barrett J; Young N S
Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lymphocytes in vitro and in vivo.
Blood 2000;95(7):2269-74.
2000: Crapnell K; Zanjani E D; Chaudhuri A; Ascensao J L; St Jeor S; Maciejewski J P
In vitro infection of megakaryocytes and their precursors by human cytomegalovirus.
Blood 2000;95(2):487-93.
1999: Chaudhuri A R; St Jeor S; Maciejewski J P
Apoptosis induced by human cytomegalovirus infection can be enhanced by cytokines to limit the spread of virus.
Experimental hematology 1999;27(7):1194-203.
1999: Selleri C; Maciejewski J P; De Rosa G; Raiola A; Risitano A M; Picardi M; Pezzullo L; Luciano L; Ricci P; Varriale G; Della Cioppa P; Del Vecchio L; Rotoli B
Long-lasting decrease of marrow and circulating long-term culture initiating cells after allogeneic bone marrow transplant.
Bone marrow transplantation 1999;23(10):1029-37.
1999: Maciejewski J P; St Jeor S C
Human cytomegalovirus infection of human hematopoietic progenitor cells.
Leukemia & lymphoma 1999;33(1-2):1-13.
1998: Sloand E M; Maciejewski J P; Dunn D; Moss J; Brewer B; Kirby M; Young N S
Correction of the PNH defect by GPI-anchored protein transfer.
Blood 1998;92(11):4439-45.
1998: Sloand E M; Young N S; Sato T; Kim S; Maciejewski J P
Inhibition of interleukin-1beta-converting enzyme in human hematopoietic progenitor cells results in blockade of cytokine-mediated apoptosis and expansion of their proliferative potential.
Experimental hematology 1998;26(11):1093-9.
1998: Sato T; Kim S; Selleri C; Young N S; Maciejewski J P
Measurement of secondary colony formation after 5 weeks in long-term cultures in patients with myelodysplastic syndrome.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(8):1187-94.
1998: Selleri C; Maciejewski J P; Pane F; Luciano L; Raiola A M; Mostarda I; Salvatore F; Rotoli B
Fas-mediated modulation of Bcr/Abl in chronic myelogenous leukemia results in differential effects on apoptosis.
Blood 1998;92(3):981-9.
1998: Weichold F F; Zella D; Barabitskaja O; Maciejewski J P; Dunn D E; Sloand E M; Young N S
Neither human immunodeficiency virus-1 (HIV-1) nor HIV-2 infects most-primitive human hematopoietic stem cells as assessed in long-term bone marrow cultures.
Blood 1998;91(3):907-15.
1998: Sloand E M; Maciejewski J P; Sato T; Bruny J; Kumar P; Kim S; Weichold F F; Young N S
The role of interleukin-converting enzyme in Fas-mediated apoptosis in HIV-1 infection.
The Journal of clinical investigation 1998;101(1):195-201.
1997: Selleri C; Sato T; Raiola A M; Rotoli B; Young N S; Maciejewski J P
Induction of nitric oxide synthase is involved in the mechanism of Fas-mediated apoptosis in haemopoietic cells.
British journal of haematology 1997;99(3):481-9.
1997: Sato T; Selleri C; Young N S; Maciejewski J P
Inhibition of interferon regulatory factor-1 expression results in predominance of cell growth stimulatory effects of interferon-gamma due to phosphorylation of Stat1 and Stat3.
Blood 1997;90(12):4749-58.
1997: Sloand E M; Young N S; Sato T; Kumar P; Kim S; Weichold F F; Maciejewski J P
Secondary colony formation after long-term bone marrow culture using peripheral blood and bone marrow of HIV-infected patients.
AIDS (London, England) 1997;11(13):1547-53.
1997: Zhuravskaya T; Maciejewski J P; Netski D M; Bruening E; Mackintosh F R; St Jeor S
Spread of human cytomegalovirus (HCMV) after infection of human hematopoietic progenitor cells: model of HCMV latency.
Blood 1997;90(6):2482-91.
1997: Sato T; Selleri C; Anderson S; Young N S; Maciejewski J P
Expression and modulation of cellular receptors for interferon-gamma, tumour necrosis factor, and Fas on human bone marrow CD34+ cells.
British journal of haematology 1997;97(2):356-65.
1997: Sloand E M; Young N S; Kumar P; Weichold F F; Sato T; Maciejewski J P
Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication.
Blood 1997;89(4):1357-63.
1997: Maciejewski J P; Sloand E M; Sato T; Anderson S; Young N S
Impaired hematopoiesis in paroxysmal nocturnal hemoglobinuria/aplastic anemia is not associated with a selective proliferative defect in the glycosylphosphatidylinositol-anchored protein-deficient clone.
Blood 1997;89(4):1173-81.
1997: Selleri C; Sato T; Del Vecchio L; Luciano L; Barrett A J; Rotoli B; Young N S; Maciejewski J P
Involvement of Fas-mediated apoptosis in the inhibitory effects of interferon-alpha in chronic myelogenous leukemia.
Blood 1997;89(3):957-64.
1996: Maciejewski J P; Young N S; Yu M; Anderson S M; Sloand E M
Analysis of the expression of glycosylphosphatidylinositol anchored proteins on platelets from patients with paroxysmal nocturnal hemoglobinuria.
Thrombosis research 1996;83(6):433-47.
1996: Maciejewski J P; Selleri C; Sato T; Anderson S; Young N S
A severe and consistent deficit in marrow and circulating primitive hematopoietic cells (long-term culture-initiating cells) in acquired aplastic anemia.
Blood 1996;88(6):1983-91.
1996: Selleri C; Maciejewski J P; Sato T; Young N S
Interferon-gamma constitutively expressed in the stromal microenvironment of human marrow cultures mediates potent hematopoietic inhibition.
Blood 1996;87(10):4149-57.
1995: Sato T; Selleri C; Young N S; Maciejewski J P
Hematopoietic inhibition by interferon-gamma is partially mediated through interferon regulatory factor-1.
Blood 1995;86(9):3373-80.
1995: Maciejewski J P; Selleri C; Sato T; Anderson S; Young N S
Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia.
British journal of haematology 1995;91(1):245-52.
1995: Maciejewski J P; Selleri C; Sato T; Cho H J; Keefer L K; Nathan C F; Young N S
Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha.
The Journal of clinical investigation 1995;96(2):1085-92.
1995: Maciejewski J P; Weichold F F; Young N S; Cara A; Zella D; Reitz M S; Gallo R C
Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro.
Nature medicine 1995;1(7):667-73.
1995: Maciejewski J; Selleri C; Anderson S; Young N S
Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro.
Blood 1995;85(11):3183-90.
1994: Maciejewski J P; Weichold F F; Young N S
HIV-1 suppression of hematopoiesis in vitro mediated by envelope glycoprotein and TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(9):4303-10.
1994: Maciejewski J P; Hibbs J R; Anderson S; Katevas P; Young N S
Bone marrow and peripheral blood lymphocyte phenotype in patients with bone marrow failure.
Experimental hematology 1994;22(11):1102-10.
1994: Maciejewski J P; Anderson S; Katevas P; Young N S
Phenotypic and functional analysis of bone marrow progenitor cell compartment in bone marrow failure.
British journal of haematology 1994;87(2):227-34.
1993: Maciejewski J P; Bruening E E; Donahue R E; Sellers S E; Carter C; Young N S; St Jeor S
Infection of mononucleated phagocytes with human cytomegalovirus.
Virology 1993;195(2):327-36.
1992: Maciejewski J P; Liu J M; Green S W; Walsh C E; Plumb M; Pragnell I B; Young N S
Expression of stem cell inhibitor (SCI) gene in patients with bone marrow failure.
Experimental hematology 1992;20(9):1112-7.
1992: Maciejewski J P; Bruening E E; Donahue R E; Mocarski E S; Young N S; St Jeor S C
Infection of hematopoietic progenitor cells by human cytomegalovirus.
Blood 1992;80(1):170-8.
1991: Young N S; Rosenfeld S; Antunez-de-Mayolo J; Hibbs J; Liu J; Maciejewski J; St Jeor S; Shimomura S; Kajigaya S
Viruses and bone marrow failure.
Schweizerische medizinische Wochenschrift. Supplementum 1991;43():28-32.

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