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Alan Mackay
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Research Profile (preview)
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Chemicals & Drugs
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Network (preview)
31
Ashworth, Alan
25
Reis-Filho, Jorge
24
Fenwick, Kerry
16
Jones, Chris
14
Iravani, Marjan
14
Dexter, Tim
14
Lambros, Maryou
12
Natrajan, Rachael
10
Savage, Kay
10
Grigoriadis, Anita
6
Dowsett, Mitch
6
Schmitt, Fernando
6
O'Hare, Michael
6
Lakhani, Sunil
6
Tan, David
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Geonetwork of Alan Mackay (preview)
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All Publications
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2009: Mackay Alan; Tamber Narinder; Fenwick Kerry; Iravani Marjan; Grigoriadis Anita; Dexter Tim; Lord Christopher J; Reis-Filho Jorge S; Ashworth Alan
A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines.
Breast cancer research and treatment 2009;118(3):481-98.
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2009: Marchiò Caterina; Lambros Maryou B; Gugliotta Patrizia; Di Cantogno Ludovica Verdun; Botta Cristina; Pasini Barbara; Tan David S P; Mackay Alan; Fenwick Kerry; Tamber Narinder; Bussolati Gianni; Ashworth Alan; Reis-Filho Jorge S; Sapino Anna
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis.
The Journal of pathology 2009;219(1):16-24.
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2009: Westbury Charlotte B; Reis-Filho Jorge S; Dexter Tim; Mahler-Araujo Betania; Fenwick Kerry; Iravani Marjan; Grigoriadis Anita; Parry Suzanne; Robertson David; Mackay Alan; Ashworth Alan; Yarnold John R; Isacke Clare M
Genome-wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c-Kit, CD117) and oestrogen receptor-alpha (ERalpha) in response to therapeutic radiation.
The Journal of pathology 2009;219(1):131-40.
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2009: Lambros M B K; Tan D S P; Jones R L; Vatcheva R; Savage K; Tamber N; Fenwick K; Mackay A; Ashworth A; Reis-Filho J S
Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication.
Journal of clinical pathology 2009;62(7):604-12.
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2009: Marchiò Caterina; Iravani Marjan; Natrajan Rachael; Lambros Maryou B K; Geyer Felipe C; Savage Kay; Parry Suzanne; Tamber Narinder; Fenwick Kerry; Mackay Alan; Schmitt Fernando C; Bussolati Gianni; Ellis Ian; Ashworth Alan; Sapino Anna; Reis-Filho Jorge S
Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components.
The Journal of pathology 2009;218(3):301-15.
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2009: Natrajan Rachael; Lambros Maryou B; Rodríguez-Pinilla Socorro María; Moreno-Bueno Gema; Tan David S P; Marchió Caterina; Vatcheva Radost; Rayter Sydonia; Mahler-Araujo Betania; Fulford Laura G; Hungermann Daniela; Mackay Alan; Grigoriadis Anita; Fenwick Kerry; Tamber Narinder; Hardisson David; Tutt Andrew; Palacios Jose; Lord Christopher J; Buerger Horst; Ashworth Alan; Reis-Filho Jorge S
Tiling path genomic profiling of grade 3 invasive ductal breast cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(8):2711-22.
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2009: Tan David S P; Lambros Maryou B K; Rayter Sydonia; Natrajan Rachael; Vatcheva Radost; Gao Qiong; Marchiò Caterina; Geyer Felipe C; Savage Kay; Parry Suzanne; Fenwick Kerry; Tamber Narinder; Mackay Alan; Dexter Tim; Jameson Charles; McCluggage W Glenn; Williams Alistair; Graham Ashley; Faratian Dana; El-Bahrawy Mona; Paige Adam J; Gabra Hani; Gore Martin E; Zvelebil Marketa; Lord Christopher J; Kaye Stanley B; Ashworth Alan; Reis-Filho Jorge S
PPM1D is a potential therapeutic target in ovarian clear cell carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(7):2269-80.
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2009: Iorns Elizabeth; Lord Christopher J; Grigoriadis Anita; McDonald Sarah; Fenwick Kerry; Mackay Alan; Mein Charles A; Natrajan Rachael; Savage Kay; Tamber Narinder; Reis-Filho Jorge S; Turner Nicholas C; Ashworth Alan
Integrated functional, gene expression and genomic analysis for the identification of cancer targets.
PloS one 2009;4(4):e5120.
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2008: Vuononvirta Raisa; Sebire Neil J; Dallosso Anthony R; Reis-Filho Jorge S; Williams Richard D; Mackay Alan; Fenwick Kerry; Grigoriadis Anita; Ashworth Alan; Pritchard-Jones Kathy; Brown Keith W; Vujanic Gordan M; Jones Chris
Perilobar nephrogenic rests are nonobligate molecular genetic precursor lesions of insulin-like growth factor-II-associated Wilms tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(23):7635-44.
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2008: Marchiò C; Natrajan R; Shiu K K; Lambros M B K; Rodriguez-Pinilla S M; Tan D S P; Lord C J; Hungermann D; Fenwick K; Tamber N; Mackay A; Palacios J; Sapino A; Buerger H; Ashworth A; Reis-Filho J S
The genomic profile of HER2-amplified breast cancers: the influence of ER status.
The Journal of pathology 2008;216(4):399-407.
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2008: Marchiò C; Iravani M; Natrajan R; Lambros M B; Savage K; Tamber N; Fenwick K; Mackay A; Senetta R; Di Palma S; Schmitt F C; Bussolati G; Ellis L O; Ashworth A; Sapino A; Reis-Filho J S
Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast.
The Journal of pathology 2008;215(4):398-410.
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2008: Simpson P T; Reis-Filho J S; Lambros M B K; Jones C; Steele D; Mackay A; Iravani M; Fenwick K; Dexter T; Jones A; Reid L; Da Silva L; Shin S J; Hardisson D; Ashworth A; Schmitt F C; Palacios J; Lakhani S R
Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas.
The Journal of pathology 2008;215(3):231-44.
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2008: Arriola Edurne; Marchio Caterina; Tan David S P; Drury Suzanne C; Lambros Maryou B; Natrajan Rachael; Rodriguez-Pinilla Socorro Maria; Mackay Alan; Tamber Narinder; Fenwick Kerry; Jones Chris; Dowsett Mitch; Ashworth Alan; Reis-Filho Jorge S
Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines.
Laboratory investigation; a journal of technical methods and pathology 2008;88(5):491-503.
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2008: Kendall Anne; Anderson Helen; Dunbier Anita K; Mackay Alan; Dexter Tim; Urruticoechea Ander; Harper-Wynne Catherine; Dowsett Mitch
Impact of estrogen deprivation on gene expression profiles of normal postmenopausal breast tissue in vivo.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(4):855-63.
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2007: Natrajan Rachael; Williams Richard D; Grigoriadis Anita; Mackay Alan; Fenwick Kerry; Ashworth Alan; Dome Jeffrey S; Grundy Paul E; Pritchard-Jones Kathy; Jones Chris
Delineation of a 1Mb breakpoint region at 1p13 in Wilms tumors by fine-tiling oligonucleotide array CGH.
Genes, chromosomes & cancer 2007;46(6):607-15.
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2007: Di Palma Silvana; Lambros Maryou B K; Savage Kay; Jones Chris; Mackay Alan; Dexter Tim; Iravani Marjan; Fenwick Kerry; Ashworth Alan; Reis-Filho Jorge S
Oncocytic change in pleomorphic adenoma: molecular evidence in support of an origin in neoplastic cells.
Journal of clinical pathology 2007;60(5):492-9.
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2007: Daly-Burns Bernadette; Alam Tahirah N; Mackay Alan; Clark Jeremy; Shepherd Christopher J; Rizzo Siân; Tatoud Roger; O'Hare Michael J; Masters John R; Hudson David L
A conditionally immortalized cell line model for the study of human prostatic epithelial cell differentiation.
Differentiation; research in biological diversity 2007;75(1):35-48.
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2007: Savage Kay; Lambros Maryou B K; Robertson David; Jones Robin L; Jones Chris; Mackay Alan; James Michelle; Hornick Jason L; Pereira Emilio M; Milanezi Fernanda; Fletcher Christopher D M; Schmitt Fernando C; Ashworth Alan; Reis-Filho Jorge S
Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):90-101.
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2007: Arriola Edurne; Lambros Maryou B K; Jones Chris; Dexter Tim; Mackay Alan; Tan David S P; Tamber Narinder; Fenwick Kerry; Ashworth Alan; Dowsett Mitch; Reis-Filho Jorge S
Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation.
Laboratory investigation; a journal of technical methods and pathology 2007;87(1):75-83.
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2007: Pierga J-Y; Reis-Filho J S; Cleator S J; Dexter T; Mackay A; Simpson P; Fenwick K; Iravani M; Salter J; Hills M; Jones C; Ashworth A; Smith I E; Powles T; Dowsett M
Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy.
British journal of cancer 2007;96(2):341-51.
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2007: Natrajan R; Little S E; Sodha N; Reis-Filho J S; Mackay A; Fenwick K; Ashworth A; Perlman E J; Dome J S; Grundy P E; Pritchard-Jones K; Jones C
Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumour.
The Journal of pathology 2007;211(1):52-9.
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2007: Smalley Matthew J; Iravani Marjan; Leao Maria; Grigoriadis Anita; Kendrick Howard; Dexter Tim; Fenwick Kerry; Regan Joseph L; Britt Kara; McDonald Sarah; Lord Christopher J; Mackay Alan; Ashworth Alan
Regulator of G-protein signalling 2 mRNA is differentially expressed in mammary epithelial subpopulations and over-expressed in the majority of breast cancers.
Breast cancer research : BCR 2007;9(6):R85.
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2007: Mackay Alan; Urruticoechea Ander; Dixon J Michael; Dexter Tim; Fenwick Kerry; Ashworth Alan; Drury Suzanne; Larionov Alexey; Young Oliver; White Sharon; Miller William R; Evans Dean B; Dowsett Mitch
Molecular response to aromatase inhibitor treatment in primary breast cancer.
Breast cancer research : BCR 2007;9(3):R37.
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2006: Reis-Filho Jorge Sergio; Simpson Pete T; Turner Nicholas C; Lambros Maryou Ballo; Jones Chris; Mackay Alan; Grigoriadis Anita; Sarrio David; Savage Kay; Dexter Tim; Iravani Marjan; Fenwick Kerry; Weber Barbara; Hardisson David; Schmitt Fernando Carlos; Palacios Jose; Lakhani Sunil R; Ashworth Alan
FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6652-62.
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2006: Natrajan R; Williams R D; Hing S N; Mackay A; Reis-Filho J S; Fenwick K; Iravani M; Valgeirsson H; Grigoriadis A; Langford C F; Dovey O; Gregory S G; Weber B L; Ashworth A; Grundy P E; Pritchard-Jones K; Jones C
Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse.
The Journal of pathology 2006;210(1):49-58.
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2006: Reis-Filho J S; Pinheiro C; Lambros M B K; Milanezi F; Carvalho S; Savage K; Simpson P T; Jones C; Swift S; Mackay A; Reis R M; Hornick J L; Pereira E M; Baltazar F; Fletcher C D M; Ashworth A; Lakhani S R; Schmitt F C
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas.
The Journal of pathology 2006;209(4):445-53.
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2006: Horsley Sharon W; Mackay Alan; Iravani Marjan; Fenwick Kerry; Valgeirsson Haukur; Dexter Tim; Ashworth Alan; Kearney Lyndal
Array CGH of fusion gene-positive leukemia-derived cell lines reveals cryptic regions of genomic gain and loss.
Genes, chromosomes & cancer 2006;45(6):554-64.
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2006: Lambros Maryou B K; Simpson Pete T; Jones Chris; Natrajan Rachael; Westbury Charlotte; Steele Dawn; Savage Kay; Mackay Alan; Schmitt Fernando C; Ashworth Alan; Reis-Filho Jorge S
Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization.
Laboratory investigation; a journal of technical methods and pathology 2006;86(4):398-408.
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2006: Little Suzanne E; Vuononvirta Raisa; Reis-Filho Jorge S; Natrajan Rachael; Iravani Marjan; Fenwick Kerry; Mackay Alan; Ashworth Alan; Pritchard-Jones Kathy; Jones Chris
Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA.
Genomics 2006;87(2):298-306.
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2006: Grigoriadis Anita; Mackay Alan; Reis-Filho Jorge S; Steele Dawn; Iseli Christian; Stevenson Brian J; Jongeneel C Victor; Valgeirsson Haukur; Fenwick Kerry; Iravani Marjan; Leao Maria; Simpson Andrew J G; Strausberg Robert L; Jat Parmjit S; Ashworth Alan; Neville A Munro; O'Hare Michael J
Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data.
Breast cancer research : BCR 2006;8(5):R56.
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2006: Cleator Susan J; Powles Trevor J; Dexter Tim; Fulford Laura; Mackay Alan; Smith Ian E; Valgeirsson Haukur; Ashworth Alan; Dowsett Mitch
The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis.
Breast cancer research : BCR 2006;8(3):R32.
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2005: Reis-Filho Jorge S; Simpson Pete T; Jones Chris; Steele Dawn; Mackay Alan; Iravani Marjan; Fenwick Kerry; Valgeirsson Haukur; Lambros Maryou; Ashworth Alan; Palacios Jose; Schmitt Fernando; Lakhani Sunil R
Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity.
The Journal of pathology 2005;207(1):1-13.
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2005: Hardy K; Mansfield L; Mackay A; Benvenuti S; Ismail S; Arora P; O'Hare M J; Jat P S
Transcriptional networks and cellular senescence in human mammary fibroblasts.
Molecular biology of the cell 2005;16(2):943-53.
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2005: Brookman-Amissah N; Duchesnes C; Williamson M P; Wang Q; Ahmed A; Feneley M R; Mackay A; Freeman A; Fenwick K; Iravani M; Weber B; Ashworth A; Masters J R
Genome-wide screening for genetic changes in a matched pair of benign and prostate cancer cell lines using array CGH.
Prostate cancer and prostatic diseases 2005;8(4):335-43.
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2004: Jones Chris; Mackay Alan; Grigoriadis Anita; Cossu Antonio; Reis-Filho Jorge S; Fulford Laura; Dexter Tim; Davies Susan; Bulmer Karen; Ford Emily; Parry Suzanne; Budroni Mario; Palmieri Giuseppe; Neville A Munro; O'Hare Michael J; Lakhani Sunil R
Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer.
Cancer research 2004;64(9):3037-45.
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2003: Mackay Alan; Jones Chris; Dexter Tim; Silva Ricardo L A; Bulmer Karen; Jones Allison; Simpson Peter; Harris Robert A; Jat Parmjit S; Neville A Munro; Reis Luiz F L; Lakhani Sunil R; O'Hare Michael J
cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells.
Oncogene 2003;22(17):2680-8.
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2003: Jongeneel C Victor; Iseli Christian; Stevenson Brian J; Riggins Gregory J; Lal Anita; Mackay Alan; Harris Robert A; O'Hare Michael J; Neville A Munro; Simpson Andrew J G; Strausberg Robert L
Comprehensive sampling of gene expression in human cell lines with massively parallel signature sequencing.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4702-5.
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2002: Djelloul Siham; Tarunina Marina; Barnouin Karin; Mackay Alan; Jat Parmjit S
Differential protein expression, DNA binding and interaction with SV40 large tumour antigen implicate the p63-family of proteins in replicative senescence.
Oncogene 2002;21(7):981-9.
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