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Harald Mackenzie

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Mai Ots; Julia L Troy; Helmut G Rennke; Harald S Mackenzie; Barry M Brenner
Impact of the supplementation of kidney mass on blood pressure and progression of kidney disease.
Mamoru Kusaka; Harald S Mackenzie; Farzard Ziai; Wayne W Hancock; Nicholas L Tilney
Recipient hypertension potentiates chronic functional and structural injury of rat renal allografts.
Michael R Clarkson; Madeline Murphy; Sunil Gupta; Teresa Lambe; Harald S Mackenzie; Catherine Godson; Finian Martin; Hugh R Brady
High glucose-altered gene expression in mesangial cells. Actin-regulatory protein gene expression is triggered by oxidative stress and cytoskeletal disassembly.

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All Publications

2004: Mai Ots; Julia L Troy; Helmut G Rennke; Harald S Mackenzie; Barry M Brenner
Impact of the supplementation of kidney mass on blood pressure and progression of kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(2):337-41.
2002: Mamoru Kusaka; Harald S Mackenzie; Farzard Ziai; Wayne W Hancock; Nicholas L Tilney
Recipient hypertension potentiates chronic functional and structural injury of rat renal allografts.
Transplantation 2002;74(3):307-14.
2002: Michael R Clarkson; Madeline Murphy; Sunil Gupta; Teresa Lambe; Harald S Mackenzie; Catherine Godson; Finian Martin; Hugh R Brady
High glucose-altered gene expression in mesangial cells. Actin-regulatory protein gene expression is triggered by oxidative stress and cytoskeletal disassembly.
The Journal of biological chemistry 2002;277(12):9707-12.
2001: Mamoru Kusaka; Johann Pratschke; Markus J Wilhelm; Farzard Ziai; Kambiz Zandi-Nejad; Harald S Mackenzie; Wayne W Hancock; Nicholas L Tilney
Early and late inflammatory changes occurring in rat renal isografts from brain dead donors.
Transplantation proceedings 2001;33(1-2):867-8.
2001: Markus J Wilhelm; Johann Pratschke; Dustin Paz; Igor Laskowski; Harald S Mackenzie; Wayne W Hancock; Nicholas L Tilney
Donor hypertension and recipient immune responsiveness in chronic rat cardiac allograft rejection.
Transplantation proceedings 2001;33(1-2):321-2.
2001: MW Taal; Glenn M Chertow; Helmut G Rennke; A Gurnani; T Jiang; A Shahsafaei; Julia L Troy; Barry M Brenner; Harald S Mackenzie
Mechanisms underlying renoprotection during renin-angiotensin system blockade.
American journal of physiology. Renal physiology 2001;280(2):F343-55.
2000: MW Taal; Kambiz Zandi-Nejad; B Weening; A Shahsafaei; S Kato; KW Lee; Farzard Ziai; T Jiang; Barry M Brenner; Harald S Mackenzie
Proinflammatory gene expression and macrophage recruitment in the rat remnant kidney.
Kidney international 2000;58(4):1664-76.
2000: MW Taal; S A Omer; MK Nadim; Harald S Mackenzie
Cellular and molecular mediators in common pathway mechanisms of chronic renal disease progression.
Current opinion in nephrology and hypertension 2000;9(4):323-31.
2000: Farzard Ziai; H Nagano; M Kusaka; A J Coito; Julia L Troy; KC Nadeau; Helmut G Rennke; Nicholas L Tilney; Barry M Brenner; Harald S Mackenzie
Renal allograft protection with losartan in Fisher-->Lewis rats: hemodynamics, macrophages, and cytokines.
Kidney international 2000;57(6):2618-25.
2000: Ruth McMahon; Madeline Murphy; Michael R Clarkson; MW Taal; Harald S Mackenzie; Catherine Godson; Finian Martin; Hugh R Brady
IHG-2, a mesangial cell gene induced by high glucose, is human gremlin. Regulation by extracellular glucose concentration, cyclic mechanical strain, and transforming growth factor-beta1.
The Journal of biological chemistry 2000;275(14):9901-4.
2000: Mamoru Kusaka; Johann Pratschke; Markus J Wilhelm; Farzard Ziai; Kambiz Zandi-Nejad; Harald S Mackenzie; Wayne W Hancock; Nicholas L Tilney
Activation of inflammatory mediators in rat renal isografts by donor brain death.
Transplantation 2000;69(3):405-10.
1999: S Kato; Valerie A Luyckx; Mai Ots; KW Lee; Farzard Ziai; Julia L Troy; Barry M Brenner; Harald S Mackenzie
Renin-angiotensin blockade lowers MCP-1 expression in diabetic rats.
Kidney international 1999;56(3):1037-48.
1999: Harald S Mackenzie; Farzard Ziai; S A Omer; MK Nadim; MW Taal
Angiotensin receptor blockers in chronic renal disease: the promise of a bright clinical future.
Journal of the American Society of Nephrology : JASN 1999;10 Suppl 12():S283-6.
1999: Madeline Murphy; Catherine Godson; S Cannon; S Kato; Harald S Mackenzie; Finian Martin; Hugh R Brady
Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells.
The Journal of biological chemistry 1999;274(9):5830-4.
1999: Mamoru Kusaka; Farzard Ziai; Wayne W Hancock; Nicholas L Tilney; Harald S Mackenzie
Systemic hypertension accelerates chronic rejection of renal allografts in the rat.
Transplantation proceedings 1999;31(1-2):869.
1998: K Totsune; Harald S Mackenzie; H Totsune; Julia L Troy; J Lytton; Barry M Brenner
Upregulation of atrial natriuretic peptide gene expression in remnant kidney of rats with reduced renal mass.
Journal of the American Society of Nephrology : JASN 1998;9(9):1613-9.
1998: M Takada; KC Nadeau; Wayne W Hancock; Harald S Mackenzie; Gray D Shaw; Ana Maria Waaga; Anil Chandraker; Mohamed H Sayegh; Nicholas L Tilney
Effects of explosive brain death on cytokine activation of peripheral organs in the rat.
Transplantation 1998;65(12):1533-42.
1998: Mai Ots; Harald S Mackenzie; Julia L Troy; Helmut G Rennke; Barry M Brenner
Effects of combination therapy with enalapril and losartan on the rate of progression of renal injury in rats with 5/6 renal mass ablation.
Journal of the American Society of Nephrology : JASN 1998;9(2):224-30.
1998: M J Hébert; Steven R Gullans; Harald S Mackenzie; Hugh R Brady
Apoptosis of endothelial cells is associated with paracrine induction of adhesion molecules: evidence for an interleukin-1beta-dependent paracrine loop.
The American journal of pathology 1998;152(2):523-32.
1998: Harald S Mackenzie; Barry M Brenner
Current strategies for retarding progression of renal disease.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1998;31(1):161-70.
1997: Harald S Mackenzie; Farzard Ziai; H Nagano; H Azuma; Julia L Troy; Helmut G Rennke; Nicholas L Tilney; Barry M Brenner
Candesartan cilexetil reduces chronic renal allograft injury in Fisher-->Lewis rats.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1997;15(6):S21-5.
1997: Harald S Mackenzie; Mai Ots; Farzard Ziai; KW Lee; S Kato; Barry M Brenner
Angiotensin receptor antagonists in experimental models of chronic renal failure.
Kidney international. Supplement 1997;63():S140-3.
1997: Barry M Brenner; Harald S Mackenzie
Nephron mass as a risk factor for progression of renal disease.
Kidney international. Supplement 1997;63():S124-7.
1997: G M Chertow; Barry M Brenner; Motomi Mori; Harald S Mackenzie; E L Milford
Antigen-independent determinants of graft survival in living-related kidney transplantation.
Kidney international. Supplement 1997;63():S84-6.
1997: H Azuma; KC Nadeau; M Takada; Harald S Mackenzie; Nicholas L Tilney
Cellular and molecular predictors of chronic renal dysfunction after initial ischemia/reperfusion injury of a single kidney.
Transplantation 1997;64(2):190-7.
1997: H Azuma; KC Nadeau; Harald S Mackenzie; Barry M Brenner; Nicholas L Tilney
Nephron mass modulates the hemodynamic, cellular, and molecular response of the rat renal allograft.
Transplantation 1997;63(4):519-28.
1996: Glenn M Chertow; E L Milford; Harald S Mackenzie; B M Brenner
Antigen-independent determinants of cadaveric kidney transplant failure.
JAMA : the journal of the American Medical Association 1996;276(21):1732-6.
1996: Farzard Ziai; Mai Ots; A P Provoost; Julia L Troy; Helmut G Rennke; Barry M Brenner; Harald S Mackenzie
The angiotensin receptor antagonist, irbesartan, reduces renal injury in experimental chronic renal failure.
Kidney international. Supplement 1996;57():S132-6.
1996: Harald S Mackenzie; Elizabeth Victoria Lawler; Barry M Brenner
Congenital oligonephropathy: The fetal flaw in essential hypertension?
Kidney international. Supplement 1996;55():S30-4.
1996: Barry M Brenner; Elizabeth Victoria Lawler; Harald S Mackenzie
The hyperfiltration theory: a paradigm shift in nephrology.
Kidney international 1996;49(6):1774-7.
1996: Harald S Mackenzie; H Azuma; Julia L Troy; Helmut G Rennke; Nicholas L Tilney; Barry M Brenner
Augmenting kidney mass at transplantation abrogates chronic renal allograft injury in rats.
Proceedings of the Association of American Physicians 1996;108(2):127-33.
1995: Glenn M Chertow; Barry M Brenner; Harald S Mackenzie; E L Milford
Non-immunologic predictors of chronic renal allograft failure: data from the United Network of Organ Sharing.
Kidney international. Supplement 1995;52():S48-51.
1995: Harald S Mackenzie; H Azuma; Helmut G Rennke; N L Tilney; Barry M Brenner
Renal mass as a determinant of late allograft outcome: insights from experimental studies in rats.
Kidney international. Supplement 1995;52():S38-42.
1995: P L Zhang; Harald S Mackenzie; K Totsune; Julia L Troy; Barry M Brenner
Renal effects of high-dose natriuretic peptide receptor blockade in rats with congestive heart failure.
Circulation research 1995;77(6):1240-5.
1995: Harald S Mackenzie; Barry M Brenner
Fewer nephrons at birth: a missing link in the etiology of essential hypertension?
American journal of kidney diseases : the official journal of the National Kidney Foundation 1995;26(1):91-8.
1995: U W Heemann; H Azuma; Stefan G Tullius; Harald S Mackenzie; C Schmid; B M Brenner; Nicholas L Tilney
Influence of renal mass on chronic kidney allograft rejection in rats.
Transplantation proceedings 1995;27(1):549.
1994: U W Heemann; H Azuma; Stefan G Tullius; Harald S Mackenzie; Barry M Brenner; Nicholas L Tilney
The contribution of reduced functioning mass to chronic kidney allograft dysfunction in rats.
Transplantation 1994;58(12):1317-22.
1994: Harald S Mackenzie; Stefan G Tullius; U W Heemann; H Azuma; Helmut G Rennke; Barry M Brenner; Nicholas L Tilney
Nephron supply is a major determinant of long-term renal allograft outcome in rats.
The Journal of clinical investigation 1994;94(5):2148-52.
1994: Harald S Mackenzie; Julia L Troy; Helmut G Rennke; Barry M Brenner
TCV 116 prevents progressive renal injury in rats with extensive renal mass ablation.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1994;12(9):S11-6.
1994: P L Zhang; Wladimiro Jiménez; Harald S Mackenzie; J Guo; Julia L Troy; J Ros; P Angeli; Vicente Arroyo; Barry M Brenner
HS-142-1, a potent antagonist of natriuretic peptides in vitro and in vivo.
Journal of the American Society of Nephrology : JASN 1994;5(4):1099-105.
1994: U W Heemann; Stefan G Tullius; H Azuma; Harald S Mackenzie; B M Brenner; Nicholas L Tilney
Evidence for a beneficial effect of increased functional kidney mass upon chronic kidney rejection in rats.
Transplantation proceedings 1994;26(4):2047.
1994: P L Zhang; Harald S Mackenzie; Julia L Troy; Barry M Brenner
Effects of natriuretic peptide receptor inhibition on remnant kidney function in rats.
Kidney international 1994;46(2):414-20.
1994: P L Zhang; Harald S Mackenzie; Julia L Troy; Barry M Brenner
Effects of an atrial natriuretic peptide receptor antagonist on glomerular hyperfiltration in diabetic rats.
Journal of the American Society of Nephrology : JASN 1994;4(8):1564-70.