FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Ian MacLennan

Research Profile

Anatomy

Living Beings

Physiology

Chemicals & Drugs

T Independent Antigens

Co-author Network

Publications

TOP 3
Karine Serre; Kai-Michael Toellner; Katrin Moser; Antal Rot; Roger Bird; Ruth E Coughlan; Adam F Cunningham; Jocelyne Demengeot; Alastair Ferraro; Elin Hub; Andreia C Lino; Ian C M MacLennan; Rudolf Manz; Elodie Mohr
CD8 T cells induce T-bet-dependent migration toward CXCR3 ligands by differentiated B cells produced during responses to alum-protein vaccines.
Jennifer L Marshall; Lalit Pallan; Yang Zhang; Adam F Cunningham; Mei-Chi Hsu; Mahmood Khan; Ian C M MacLennan; Kai-Michael Toellner
Early B blasts acquire a capacity for Ig class switch recombination that is lost as they become plasmablasts.
Adriana Flores-Langarica; Ian R Henderson; Jessica Hitchcock; Mahmood Khan; Ian C M MacLennan; Jennifer L Marshall; Elodie Mohr; Ewan A Ross; Nico van Rooijen; Saeeda Bobat; Ruth E Coughlan; Adam F Cunningham
T-zone localized monocyte-derived dendritic cells promote Th1 priming to Salmonella.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Ian MacLennan (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Karine Serre; Kai-Michael Toellner; Katrin Moser; Antal Rot; Roger Bird; Ruth E Coughlan; Adam F Cunningham; Jocelyne Demengeot; Alastair Ferraro; Elin Hub; Andreia C Lino; Ian C M MacLennan; Rudolf Manz; Elodie Mohr
CD8 T cells induce T-bet-dependent migration toward CXCR3 ligands by differentiated B cells produced during responses to alum-protein vaccines.
Blood 2012;120(23):4552-9.
2011: Jennifer L Marshall; Lalit Pallan; Yang Zhang; Adam F Cunningham; Mei-Chi Hsu; Mahmood Khan; Ian C M MacLennan; Kai-Michael Toellner
Early B blasts acquire a capacity for Ig class switch recombination that is lost as they become plasmablasts.
European journal of immunology 2011;41(12):3506-12.
2011: Adriana Flores-Langarica; Ian R Henderson; Jessica Hitchcock; Mahmood Khan; Ian C M MacLennan; Jennifer L Marshall; Elodie Mohr; Ewan A Ross; Nico van Rooijen; Saeeda Bobat; Ruth E Coughlan; Adam F Cunningham
T-zone localized monocyte-derived dendritic cells promote Th1 priming to Salmonella.
European journal of immunology 2011;41(9):2654-65.
2011: Ewan A Ross; Steve P Watson; Nikita Abhyankar; Saeeda Bobat; Christopher D Buckley; James Charlesworth; Ruth E Coughlan; Adriana Flores-Langarica; Cristina Gil; Ian R Henderson; Jessica Hitchcock; Khiyam Hussain; Mahmood Khan; Constantino López-Macías; Ian C M MacLennan; Jennifer L Marshall; Adam F Cunningham
CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infection.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(4):1553-65.
2011: Karine Serre; Elodie Mohr; Cécile Bénézech; Roger Bird; Mahmood Khan; Jorge H Caamaño; Adam F Cunningham; Ian C M MacLennan
Selective effects of NF-κB1 deficiency in CD4⁺ T cells on Th2 and TFh induction by alum-precipitated protein vaccines.
European journal of immunology 2011;41(6):1573-82.
2011: Saeeda Bobat; Adriana Flores-Langarica; Jessica Hitchcock; Jennifer L Marshall; Robert Kingsley; Margaret Goodall; Cristina Gil-Cruz; Karine Serre; Denisse Leyton; Shirdi E Letran; Fabrina M C Gaspal; Rebecca Chester; Jayne L Chamberlain; Gordon Dougan; Constantino López-Macías; Ian R Henderson; James Alexander; Ian C M MacLennan; Adam F Cunningham
Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection.
European journal of immunology 2011;41(6):1606-18.
2011: Karine Serre; Kai-Michael Toellner; Cécile Bénézech; Roger Bird; Saeeda Bobat; Susan Chan; Adam F Cunningham; Guillaume Desanti; Philippe Kastner; Ian C M MacLennan; Elodie Mohr
Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.
PloS one 2011;6(6):e20731.
2010: Elodie Mohr; Adam F Cunningham; Kai-Michael Toellner; Saeeda Bobat; Ruth E Coughlan; Roger A Bird; Ian C M MacLennan; Karine Serre
IFN-{gamma} produced by CD8 T cells induces T-bet-dependent and -independent class switching in B cells in responses to alum-precipitated protein vaccine.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(40):17292-7.
2010: Oliver Winter; Katrin Moser; Elodie Mohr; Dimitra Zotos; Henriette Kaminski; Martin Szyska; Katrin Roth; David M Wong; Christof Dame; David M Tarlinton; Harald Schulze; Ian C M MacLennan; Rudolf A Manz
Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow.
Blood 2010;116(11):1867-75.
2010: Karine Serre; Elodie Mohr; Fabrina Gaspal; Peter J L Lane; Roger Bird; Adam F Cunningham; Ian C M MacLennan
IL-4 directs both CD4 and CD8 T cells to produce Th2 cytokines in vitro, but only CD4 T cells produce these cytokines in response to alum-precipitated protein in vivo.
Molecular immunology 2010;47(10):1914-22.
2010: Melania Capasso; Mandeep K Bhamrah; Tom Henley; Robert S Boyd; C Langlais; Kelvin Cain; David Dinsdale; Karen Pulford; Mahmood Khan; Boris Musset; Vladimir V Cherny; Deri Morgan; Randy D Gascoyne; Elena Vigorito; Thomas DeCoursey; Ian C M MacLennan; Martin J S Dyer
HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species.
Nature immunology 2010;11(3):265-72.
2009: Cristina Gil-Cruz; Saeeda Bobat; Jennifer L Marshall; Robert Kingsley; Ewan A Ross; ian henderson; Denisse Leyton; Ruth E Coughlan; Mahmood Khan; Karina T Jensen; Christopher D Buckley; Gordon Dougan; Ian C M MacLennan; Constantino López-Macías; Adam F Cunningham
The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(24):9803-8.
2009: Karine Serre; Elodie Mohr; Kai-Michael Toellner; Adam F Cunningham; Roger Bird; Mahmood Khan; Ian C M MacLennan
Early simultaneous production of intranodal CD4 Th2 effectors and recirculating rapidly responding central-memory-like CD4 T cells.
European journal of immunology 2009;39(6):1573-86.
2009: Elodie Mohr; Karine Serre; Rudolf A Manz; Adam F Cunningham; Mahmood Khan; Debbie L Hardie; Roger Bird; Ian C M MacLennan
Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironments where plasmablasts mature.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2113-23.
2008: Karine Serre; Elodie Mohr; Kai-Michael Toellner; Adam F Cunningham; Samuel Granjeaud; Roger Bird; Ian C M MacLennan
Molecular differences between the divergent responses of ovalbumin-specific CD4 T cells to alum-precipitated ovalbumin compared to ovalbumin expressed by Salmonella.
Molecular immunology 2008;45(13):3558-66.
2008: Ian C M MacLennan
B cells: the follicular dimension of the marginal zone.
Immunology and cell biology 2008;86(3):219-20.
2008: Fabrina M C Gaspal; Vasilios Bekiaris; Mi-Yeon Kim; David Withers; Saeeda Bobat; Ian C M MacLennan; Graham Anderson; Peter J L Lane; Adam F Cunningham
Critical synergy of CD30 and OX40 signals in CD4 T cell homeostasis and Th1 immunity to Salmonella.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):2824-9.
2008: Alastair J Ferraro; Mark T Drayson; Caroline O S Savage; Ian C M MacLennan
Levels of autoantibodies, unlike antibodies to all extrinsic antigen groups, fall following B cell depletion with Rituximab.
European journal of immunology 2008;38(1):292-8.
2008: Di Yu; Matthew C Cook; Dong-Mi Shin; Diego G Silva; Jennifer Marshall; Kai-Michael Toellner; Wendy L Havran; Pico Caroni; Michael P Cooke; Herbert C Morse; Ian C M MacLennan; Christopher C Goodnow; Carola G Vinuesa
Axon growth and guidance genes identify T-dependent germinal centre B cells.
Immunology and cell biology 2008;86(1):3-14.
2007: Elena Vigorito; Kerry L Perks; Cei Abreu-Goodger; Sam Bunting; Zou Xiang; Susan Kohlhaas; Partha P Das; Eric A Miska; Antony Rodriguez; Allan Bradley; Kenneth G C Smith; Cristina Rada; Anton J Enright; Kai-Michael Toellner; Ian C M MacLennan; Martin Turner
microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells.
Immunity 2007;27(6):847-59.
2007: Ian C M MacLennan
Holding antigen where B cells can find it.
Nature immunology 2007;8(9):909-10.
2007: Sanjiv A Luther; Karine Serre; Adam F Cunningham; Mahmood Khan; Hans Acha-Orbea; Ian C M MacLennan; Kai-Michael Toellner
Recirculating CD4 memory T cells mount rapid secondary responses without major contributions from follicular CD4 effectors and B cells.
European journal of immunology 2007;37(6):1476-84.
2007: Adam F Cunningham; Fabrina M C Gaspal; Karine Serre; Elodie Mohr; ian henderson; Anthony Scott-Tucker; Sinead M Kenny; Mahmood Khan; Kai-Michael Toellner; Peter J L Lane; Ian C M MacLennan
Salmonella induces a switched antibody response without germinal centers that impedes the extracellular spread of infection.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6200-7.
2006: Mei-Chi Hsu; Kai-Michael Toellner; Carola G Vinuesa; Ian C M MacLennan
B cell clones that sustain long-term plasmablast growth in T-independent extrafollicular antibody responses.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):5905-10.
2005: Ian C M MacLennan
Germinal centers still hold secrets.
Immunity 2005;22(6):656-7.
2004: Xiangao Huang; Maurizio Di Liberto; Adam F Cunningham; Lin Kang; Shuhua Cheng; Scott Ely; Hsiou-Chi Liou; Ian C M MacLennan; Selina Chen-Kiang
Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(51):17789-94.
2004: Adam F Cunningham; Mahmood Khan; Jennifer Ball; Kai-Michael Toellner; Karine Serre; Elodie Mohr; Ian C M MacLennan
Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1.
European journal of immunology 2004;34(11):2986-95.
2004: Adam F Cunningham; Karine Serre; Kai-Michael Toellner; Mahmood Khan; James Alexander; Frank Brombacher; Ian C M MacLennan
Pinpointing IL-4-independent acquisition and IL-4-influenced maintenance of Th2 activity by CD4 T cells.
European journal of immunology 2004;34(3):686-94.
2003: Ian C M MacLennan; Kai-Michael Toellner; Adam F Cunningham; Karine Serre; Daniel M-Y Sze; Elina Zúñiga; Matthew C Cook; Carola G Vinuesa
Extrafollicular antibody responses.
Immunological reviews 2003;194():8-18.
2003: Eunice N Hatada; Richard K G Do; Amos Orlofsky; Hsiou-Chi Liou; Michael B Prystowsky; Ian C M MacLennan; Jorge Caamano; Selina Chen-Kiang
NF-kappa B1 p50 is required for BLyS attenuation of apoptosis but dispensable for processing of NF-kappa B2 p100 to p52 in quiescent mature B cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):761-8.
2003: Ariel H Achtman; Mahmood Khan; Ian C M MacLennan; Jean Langhorne
Plasmodium chabaudi chabaudi infection in mice induces strong B cell responses and striking but temporary changes in splenic cell distribution.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):317-24.
2003: Carola G Vinuesa; Daniel M-Y Sze; Matthew C Cook; Kai-Michael Toellner; Gerry G B Klaus; Jennifer Ball; Ian C M MacLennan
Recirculating and germinal center B cells differentiate into cells responsive to polysaccharide antigens.
European journal of immunology 2003;33(2):297-305.
2002: Carola G Vinuesa; Matthew C Cook; Michael P Cooke; Ian C M MacLennan; Christopher C Goodnow
Analysis of B cell memory formation using DNA microarrays.
Annals of the New York Academy of Sciences 2002;975():33-45.
2002: Adam F Cunningham; Padraic G Fallon; Mahmood Khan; Sonia Vacheron; Hans Acha-Orbea; Ian C M MacLennan; Andrew N J McKenzie; Kai-Michael Toellner
Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13, and B cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):2900-6.
2002: Ian C M MacLennan; Carola G Vinuesa
Dendritic cells, BAFF, and APRIL: innate players in adaptive antibody responses.
Immunity 2002;17(3):235-8.
2002: Michelle R Tourigny; Josie Ursini-Siegel; Hayyoung Lee; Kai-Michael Toellner; Adam F Cunningham; David S Franklin; Scott Ely; Meihong Chen; Xiao-Feng Qin; Yue Xiong; Ian C M MacLennan; Selina Chen-Kiang
CDK inhibitor p18(INK4c) is required for the generation of functional plasma cells.
Immunity 2002;17(2):179-89.
2002: Herbert C Morse; Miriam R Anver; Torgny N Fredrickson; Diana C Haines; Alan W Harris; Nancy Lee Harris; Elaine S Jaffe; Scott C Kogan; Ian C M MacLennan; Paul K Pattengale; Jerrold M Ward
Bethesda proposals for classification of lymphoid neoplasms in mice.
Blood 2002;100(1):246-58.
2002: Scott C Kogan; Jerrold M Ward; Miriam R Anver; Jules J Berman; CORY BRAYTON; Robert Cardiff; John S Carter; Sherri de Coronado; James R Downing; Torgny N Fredrickson; Diana C Haines; Alan W Harris; Nancy Lee Harris; Hiroshi Hiai; Elaine S Jaffe; Ian C M MacLennan; Pier Paolo Pandolfi; Paul K Pattengale; Archibald S Perkins; R Mark Simpson; Mark S Tuttle; Joanne F Wong; Herbert C Morse
Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice.
Blood 2002;100(1):238-45.
2002: Kai-Michael Toellner; William E Jenkinson; Dale R Taylor; Mahmood Khan; Daniel M-Y Sze; David M Sansom; Carola G Vinuesa; Ian C M MacLennan
Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers.
The Journal of experimental medicine 2002;195(3):383-9.
2001: Eugene McCloskey; Janet A Dunn; John A Kanis; Ian C M MacLennan; Mark T Drayson
Long-term follow-up of a prospective, double-blind, placebo-controlled randomized trial of clodronate in multiple myeloma.
British journal of haematology 2001;113(4):1035-43.
2001: Carola G Vinuesa; Y Sunners; Judit Pongracz; Jennifer Ball; Kai-Michael Toellner; D Taylor; Ian C M MacLennan; Matthew C Cook
Tracking the response of Xid B cells in vivo: TI-2 antigen induces migration and proliferation but Btk is essential for terminal differentiation.
European journal of immunology 2001;31(5):1340-50.
2001: Nathalie Wehrli; Daniel F Legler; Daniela Finke; Kai-Michael Toellner; Pius Loetscher; Marco Baggiolini; Ian C M MacLennan; Hans Acha-Orbea
Changing responsiveness to chemokines allows medullary plasmablasts to leave lymph nodes.
European journal of immunology 2001;31(2):609-16.
2000: Daniel M-Y Sze; Kai-Michael Toellner; C García de Vinuesa; Dale R Taylor; Ian C M MacLennan
Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival.
The Journal of experimental medicine 2000;192(6):813-21.
2000: Ian C M MacLennan; C García de Vinuesa; Montse Casamayor
B-cell memory and the persistence of antibody responses.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1395):345-50.
2000: C G de Vinuesa; Matthew C Cook; Jennifer Ball; M Drew; Y Sunners; Marilia I Cascalho; Matthias Wabl; Gerry G B Klaus; Ian C M MacLennan
Germinal centers without T cells.
The Journal of experimental medicine 2000;191(3):485-94.
1999: C García de Vinuesa; Adam Gulbranson-Judge; Mahmood Khan; P O'Leary; Marilia I Cascalho; Matthias Wabl; Gerry G B Klaus; M J Owen; Ian C M MacLennan
Dendritic cells associated with plasmablast survival.
European journal of immunology 1999;29(11):3712-21.
1999: C García de Vinuesa; Ian C M MacLennan; Mary Holman; Gerry G B Klaus
Anti-CD40 antibody enhances responses to polysaccharide without mimicking T cell help.
European journal of immunology 1999;29(10):3216-24.
1999: Hans Acha-Orbea; Daniela Finke; Antoine Attinger; S Schmid; Nathalie Wehrli; Sonia Vacheron; I Xenarios; Léonardo Scarpellino; Kai-Michael Toellner; Ian C M MacLennan; Sanjiv A Luther
Interplays between mouse mammary tumor virus and the cellular and humoral immune response.
Immunological reviews 1999;168():287-303.
1999: C García de Vinuesa; P O'Leary; Daniel M-Y Sze; Kai-Michael Toellner; Ian C M MacLennan
T-independent type 2 antigens induce B cell proliferation in multiple splenic sites, but exponential growth is confined to extrafollicular foci.
European journal of immunology 1999;29(4):1314-23.
1999: Adam Gulbranson-Judge; Victor L J Tybulewicz; A E Walters; Kai-Michael Toellner; Ian C M MacLennan; Martin Turner
Defective immunoglobulin class switching in Vav-deficient mice is attributable to compromised T cell help.
European journal of immunology 1999;29(2):477-87.
1998: Kai-Michael Toellner; Sanjiv A Luther; Daniel M-Y Sze; R K Choy; Dale R Taylor; Ian C M MacLennan; Hans Acha-Orbea
T helper 1 (Th1) and Th2 characteristics start to develop during T cell priming and are associated with an immediate ability to induce immunoglobulin class switching.
The Journal of experimental medicine 1998;187(8):1193-204.
1998: Ian C M MacLennan
B-cell receptor regulation of peripheral B cells.
Current opinion in immunology 1998;10(2):220-5.
1998: Mark T Drayson; C E Chapman; Janet A Dunn; AB Olujohungbe; Ian C M MacLennan
MRC trial of alpha2b-interferon maintenance therapy in first plateau phase of multiple myeloma. MRC Working Party on Leukaemia in Adults.
British journal of haematology 1998;101(1):195-202.
1998: Eugene McCloskey; Ian C M MacLennan; Mark T Drayson; C Chapman; J Dunn; John A Kanis
A randomized trial of the effect of clodronate on skeletal morbidity in multiple myeloma. MRC Working Party on Leukaemia in Adults.
British journal of haematology 1998;100(2):317-25.
1997: Martin Turner; Adam Gulbranson-Judge; M E Quinn; A E Walters; Ian C M MacLennan; Victor L J Tybulewicz
Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool.
The Journal of experimental medicine 1997;186(12):2013-21.
1997: Ian C M MacLennan; Montse Casamayor; Kai-Michael Toellner; Adam Gulbranson-Judge; John Gordon
Memory B-cell clones and the diversity of their members.
Seminars in immunology 1997;9(4):229-34.
1997: Sanjiv A Luther; Adam Gulbranson-Judge; Hans Acha-Orbea; Ian C M MacLennan
B cell response and histology of a retroviral infection in vivo.
Annals of the New York Academy of Sciences 1997;815():465-6.
1997: Adam Gulbranson-Judge; Montse Casamayor; Ian C M MacLennan
Mutually dependent T and B cell responses in germinal centers.
Annals of the New York Academy of Sciences 1997;815():199-210.
1997: Ian C M MacLennan; Adam Gulbranson-Judge; Kai-Michael Toellner; Montse Casamayor; E Chan; Daniel M-Y Sze; Sanjiv A Luther; H A Orbea
The changing preference of T and B cells for partners as T-dependent antibody responses develop.
Immunological reviews 1997;156():53-66.
1997: Sanjiv A Luther; Adam Gulbranson-Judge; Hans Acha-Orbea; Ian C M MacLennan
Viral superantigen drives extrafollicular and follicular B cell differentiation leading to virus-specific antibody production.
The Journal of experimental medicine 1997;185(3):551-62.
1997: Montse Casamayor; Adam Gulbranson-Judge; Ian C M MacLennan
T cells in the selection of germinal center B cells.
Chemical immunology 1997;67():27-44.
1996: Adam Gulbranson-Judge; Ian C M MacLennan
Sequential antigen-specific growth of T cells in the T zones and follicles in response to pigeon cytochrome c.
European journal of immunology 1996;26(8):1830-7.
1996: Montse Casamayor; J Feuillard; J Ball; M Drew; Ian C M MacLennan
Centrocytes rapidly adopt a memory B cell phenotype on co-culture with autologous germinal centre T cell-enriched preparations.
International immunology 1996;8(5):737-44.
1996: Kai-Michael Toellner; Adam Gulbranson-Judge; D R Taylor; Daniel M-Y Sze; Ian C M MacLennan
Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation.
The Journal of experimental medicine 1996;183(5):2303-12.
1995: Montse Casamayor; M Khan; Ian C M MacLennan
A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex.
The Journal of experimental medicine 1995;181(4):1293-301.
1995: Ian C M MacLennan
Autoimmunity. Deletion of autoreactive B cells.
Current biology : CB 1995;5(2):103-6.
1995: D C Rowlands; N A Jones; Geoffrey Brown; M Potter; B Muschinski; Ian C M MacLennan
The proliferation-associated cytosolic protein Lap18 (stathmin) is expressed at atypically low levels in BALB/c plasmacytoma cells.
Current topics in microbiology and immunology 1995;194():73-80.
1995: N A Jones; D C Rowlands; W E Johnson; Ian C M MacLennan; Geoffrey Brown
Persistent growth of BALB/C mouse plasmacytoma and human myeloma cell lines in the presence of phorbol myristate acetate is associated with continued expression of Lap18 (stathmin).
Hematological oncology 1995;13(1):29-43.
1995: J Feuillard; D Taylor; Montse Casamayor; G D Johnson; Ian C M MacLennan
Isolation and characteristics of tonsil centroblasts with reference to Ig class switching.
International immunology 1995;7(1):121-30.
1994: Ian C M MacLennan
Germinal centers.
Annual review of immunology 1994;12():117-39.
1994: Ian C M MacLennan
Somatic mutation. From the dark zone to the light.
Current biology : CB 1994;4(1):70-2.
1993: Michelle J Holder; H Wang; Anne E Milner; M Casamayor; R Armitage; Melanie Spriggs; W C Fanslow; Ian C M MacLennan; Christopher D Gregory; John Gordon
Suppression of apoptosis in normal and neoplastic human B lymphocytes by CD40 ligand is independent of Bc1-2 induction.
European journal of immunology 1993;23(9):2368-71.
1993: Michelle J Holder; S D Abbot; Anne E Milner; Christopher D Gregory; M Casamayor; G D Johnson; Ian C M MacLennan; John Gordon
IL-2 expands and maintains IgM plasmablasts from a CD5+ subset contained within the germinal centre cell-enriched (surface IgD-/CD39- buoyant) fraction of human tonsil.
International immunology 1993;5(9):1059-66.
1993: E Y Chan; Ian C M MacLennan
Only a small proportion of splenic B cells in adults are short-lived virgin cells.
European journal of immunology 1993;23(2):357-63.
1993: Ian C M MacLennan; E Chan
The dynamic relationship between B-cell populations in adults.
Immunology today 1993;14(1):29-34.
1992: Ian C M MacLennan; Y J Liu; G D Johnson
Maturation and dispersal of B-cell clones during T cell-dependent antibody responses.
Immunological reviews 1992;126():143-61.
1992: Ian C M MacLennan; C Chapman; J Dunn; K Kelly
Combined chemotherapy with ABCM versus melphalan for treatment of myelomatosis. The Medical Research Council Working Party for Leukaemia in Adults.
Lancet 1992;339(8787):200-5.
1992: Y J Liu; G D Johnson; John Gordon; Ian C M MacLennan
Germinal centres in T-cell-dependent antibody responses.
Immunology today 1992;13(1):17-21.
1992: Ian C M MacLennan
In which cells does neoplastic transformation occur in myelomatosis?
Current topics in microbiology and immunology 1992;182():209-14.
1991: Y J Liu; J Zhang; P J Lane; E Y Chan; Ian C M MacLennan
Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens.
European journal of immunology 1991;21(12):2951-62.
1991: Michelle J Holder; Y J Liu; T Defrance; L Flores-Romo; Ian C M MacLennan; John Gordon
Growth factor requirements for the stimulation of germinal center B cells: evidence for an IL-2-dependent pathway of development.
International immunology 1991;3(12):1243-51.
1991: Y J Liu; D Y Mason; G D Johnson; S Abbot; Christopher D Gregory; D L Hardie; John Gordon; Ian C M MacLennan
Germinal center cells express bcl-2 protein after activation by signals which prevent their entry into apoptosis.
European journal of immunology 1991;21(8):1905-10.
1991: Ian C M MacLennan; Y J Liu
Marginal zone B cells respond both to polysaccharide antigens and protein antigens.
Research in immunology 1991;142(4):346-51.
1991: Y J Liu; J A Cairns; Michelle J Holder; S D Abbot; K U Jansen; J Y Bonnefoy; John Gordon; Ian C M MacLennan
Recombinant 25-kDa CD23 and interleukin 1 alpha promote the survival of germinal center B cells: evidence for bifurcation in the development of centrocytes rescued from apoptosis.
European journal of immunology 1991;21(5):1107-14.
1991: Ian C M MacLennan; G D Johnson; Y J Liu; John Gordon
The heterogeneity of follicular reactions.
Research in immunology 1991;142(3):253-7.
1991: John Gordon; J A Cairns; Y J Liu; L Flores-Romo; Ian C M MacLennan; K U Jansen; J Y Bonnefoy
Role of membrane and soluble CD23 in lymphocyte physiology.
Monographs in allergy 1991;29():156-68.
1990: M R Chapple; Ian C M MacLennan; G D Johnson
A phenotypic study of B lymphocyte subpopulations in human bone marrow.
Clinical and experimental immunology 1990;81(1):166-72.
1990: Ian C M MacLennan; Y J Liu; S Oldfield; J Zhang; P J Lane
The evolution of B-cell clones.
Current topics in microbiology and immunology 1990;159():37-63.
1989: Y J Liu; D E Joshua; G T Williams; C A Smith; John Gordon; Ian C M MacLennan
Mechanism of antigen-driven selection in germinal centres.
Nature 1989;342(6252):929-31.
1989: John Gordon; L Flores-Romo; J A Cairns; M J Millsum; P J Lane; G D Johnson; Ian C M MacLennan
CD23: a multi-functional receptor/lymphokine?
Immunology today 1989;10(5):153-7.
1989: N R Ling; D Hardie; J Lowe; G D Johnson; M Khan; Ian C M MacLennan
A phenotypic study of cells from Burkitt lymphoma and EBV-B-lymphoblastoid lines and their relationship to cells in normal lymphoid tissues.
International journal of cancer. Journal international du cancer 1989;43(1):112-8.
1989: Ian C M MacLennan; S Oldfield; Y J Liu; P J Lane
Regulation of B-cell populations.
Current topics in pathology. Ergebnisse der Pathologie 1989;79():37-57.
1989: M Beaman; Jonathan Michael; Ian C M MacLennan; Dwomoa Adu
T-cell-independent and T-cell-dependent antibody responses in patients with chronic renal failure.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1989;4(3):216-21.
1988: M Beaman; S Oldfield; Ian C M MacLennan; J Michael; Dwomoa Adu
Hypogammaglobulinaemia in nephrotic rats is attributable to hypercatabolism of IgG.
Clinical and experimental immunology 1988;74(3):425-30.
1988: J Zhang; Y J Liu; Ian C M MacLennan; D Gray; P J Lane
B cell memory to thymus-independent antigens type 1 and type 2: the role of lipopolysaccharide in B memory induction.
European journal of immunology 1988;18(9):1417-24.
1988: K A Kelly; B Durie; Ian C M MacLennan
Prognostic factors and staging systems for multiple myeloma: comparisons between the Medical Research Council studies in the United Kingdom and the Southwest Oncology Group studies in the United States.
Hematological oncology 1988;6(2):131-40.
1988: Y J Liu; S Oldfield; Ian C M MacLennan
Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones.
European journal of immunology 1988;18(3):355-62.
1988: Y J Liu; S Oldfield; Ian C M MacLennan
Thymus-independent type 2 responses in lymph nodes.
Advances in experimental medicine and biology 1988;237():113-7.
1988: J E Lortan; S Oldfield; C A Roobottom; Ian C M MacLennan
Migration of newly-produced virgin B cells from bone marrow to secondary lymphoid organs.
Advances in experimental medicine and biology 1988;237():87-92.
1988: S Oldfield; J E Lortan; M A Hyatt; Ian C M MacLennan
Marginal zone B cells and the localisation of antigen on follicular dendritic cells.
Advances in experimental medicine and biology 1988;237():99-104.
1988: Y J Liu; J E Lortan; S Oldfield; Ian C M MacLennan
CBA/N mice have marginal zone B cells with normal surface immunoglobulin phenotype.
Advances in experimental medicine and biology 1988;237():105-11.
1988: L A Walker; G D Johnson; Ian C M MacLennan
Selective induction of light chain synthesis in cultures of blood lymphocytes from patients with IgG myelomatosis.
Clinical and experimental immunology 1988;71(1):193-7.
1987: J E Lortan; C A Roobottom; S Oldfield; Ian C M MacLennan
Newly produced virgin B cells migrate to secondary lymphoid organs but their capacity to enter follicles is restricted.
European journal of immunology 1987;17(9):1311-6.
1986: P J Lane; D Gray; S Oldfield; Ian C M MacLennan
Differences in the recruitment of virgin B cells into antibody responses to thymus-dependent and thymus-independent type-2 antigens.
European journal of immunology 1986;16(12):1569-75.
1986: G D Johnson; D L Hardie; N R Ling; Ian C M MacLennan
Human follicular dendritic cells (FDC): a study with monoclonal antibodies (MoAb).
Clinical and experimental immunology 1986;64(1):205-13.
1981: J Lowe; D Hardie; Roy Jefferis; N R Ling; Pam Drysdale; P Richardson; Chandra Raykundalia; D Catty; P Appleby; R Drew; Ian C M MacLennan
Properties of monoclonal antibodies to human immunoglobulin kappa and lambda chains.
Immunology 1981;42(4):649-59.