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Alexander MacRobert

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Julie T-W Wang; Kristian Berg; Stephen G Bown; Anders Høgset; Alexander J MacRobert
Photophysical and photobiological properties of a sulfonated chlorin photosensitiser TPCS(2a) for photochemical internalisation (PCI).
Josephine P F Wong; Umber Cheema; Alexander J MacRobert; Robert A Brown
Mechanical anisotropy in compressed collagen produced by localised photodynamic cross-linking.
Stanley G Kimani; Alexander J MacRobert; Mikhail V Malakhov; James B Phillips; Tatiana A Shmigol; James I Bruce; Samantha Hammond; Jon P Golding
Fully protected glycosylated zinc (II) phthalocyanine shows high uptake and photodynamic cytotoxicity in MCF-7 cancer cells.

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2013: Julie T-W Wang; Kristian Berg; Stephen G Bown; Anders Høgset; Alexander J MacRobert
Photophysical and photobiological properties of a sulfonated chlorin photosensitiser TPCS(2a) for photochemical internalisation (PCI).
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2013;12(3):519-26.
2013: Josephine P F Wong; Umber Cheema; Alexander J MacRobert; Robert A Brown
Mechanical anisotropy in compressed collagen produced by localised photodynamic cross-linking.
Journal of the mechanical behavior of biomedical materials 2013;18():132-9.
2013: Stanley G Kimani; Alexander J MacRobert; Mikhail V Malakhov; James B Phillips; Tatiana A Shmigol; James I Bruce; Samantha Hammond; Jon P Golding
Fully protected glycosylated zinc (II) phthalocyanine shows high uptake and photodynamic cytotoxicity in MCF-7 cancer cells.
Photochemistry and photobiology 2013;89(1):139-49.
2012: Aurélie François; François Guillemin; Alexander J MacRobert; Sinan Battah; Lina Bezdetnaya; Marie-Ange D'Hallewin
Fluorescence diagnosis of bladder cancer: a novel in vivo approach using 5-aminolevulinic acid (ALA) dendrimers.
BJU international 2012;110(11 Pt C):E1155-62.
2012: Kathleen E Wright; Alexander J MacRobert; James B Phillips
Inhibition of specific cellular antioxidant pathways increases the sensitivity of neurons to meta-tetrahydroxyphenyl chlorin-mediated photodynamic therapy in a 3D co-culture model.
Photochemistry and photobiology 2012;88(6):1539-45.
2012: Matija Rojnik; Dietrich Scheglmann; Marco J Verkaik; Josephine H Woodhams; Melissa J Bovis; Lucia Celotti; Chiara Compagnin; Wijnand Helfrich; Petra Kocbek; Alexander J MacRobert; Francesca Moret; Emanuele Papini; Elena Reddi; Janko Kos
In vitro and in vivo characterization of temoporfin-loaded PEGylated PLGA nanoparticles for use in photodynamic therapy.
Nanomedicine (London, England) 2012;7(5):663-77.
2012: Melissa J Bovis; Stephen G Bown; Marilena Loizidou; Dietrich Scheglmann; Josephine H Woodhams; Alexander J MacRobert
Improved in vivo delivery of m-THPC via pegylated liposomes for use in photodynamic therapy.
Journal of controlled release : official journal of the Controlled Release Society 2012;157(2):196-205.
2012: Julie T-W Wang; Stephen G Bown; Ian M Eggleston; Francesca Giuntini; Alexander J MacRobert
Photochemical internalisation of a macromolecular protein toxin using a cell penetrating peptide-photosensitiser conjugate.
Journal of controlled release : official journal of the Controlled Release Society 2012;157(2):305-13.
2011: Chiara Compagnin; Selma Iratni; Alexander J MacRobert; Giovanni Miotto; Francesca Moret; Dietrich Scheglmann; Josephine H Woodhams; Lucia Celotti; Elena Reddi
Meta-tetra(hydroxyphenyl)chlorin-loaded liposomes sterically stabilised with poly(ethylene glycol) of different length and density: characterisation, in vitro cellular uptake and phototoxicity.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2011;10(11):1751-9.
2010: Ludovic Bourré; Francesca Giuntini; Ian M Eggleston; Charles A Mosse; Alexander J MacRobert; Michael Wilson
Effective photoinactivation of Gram-positive and Gram-negative bacterial strains using an HIV-1 Tat peptide-porphyrin conjugate.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2010;9(12):1613-20.
2009: Gabriela Di Venosa; Laura Hermida; Haydée Fukuda; María Victoria Defain; Lorena Rodriguez; Leandro Mamone; Alexander J MacRobert; Adriana Casas; Alcira Batlle
Comparation of liposomal formulations of ALA Undecanoyl ester for its use in photodynamic therapy.
Journal of photochemistry and photobiology. B, Biology 2009;96(2):152-8.
2009: Francesca Giuntini; Ludovic Bourré; Alexander J MacRobert; Michael Wilson; Ian M Eggleston
Improved peptide prodrugs of 5-ALA for PDT: rationalization of cellular accumulation and protoporphyrin IX production by direct determination of cellular prodrug uptake and prodrug metabolization.
Journal of medicinal chemistry 2009;52(13):4026-37.
2009: Adriana Casas; Sinan Battah; Gabriela Di Venosa; Paul Dobbin; Lorena Rodriguez; Haydée Fukuda; Alcira Batlle; Alexander J MacRobert
Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy.
Journal of controlled release : official journal of the Controlled Release Society 2009;135(2):136-43.
2009: Elnaz Yaghini; Alexander M Seifalian; Alexander J MacRobert
Quantum dots and their potential biomedical applications in photosensitization for photodynamic therapy.
Nanomedicine (London, England) 2009;4(3):353-63.
2009: L Bourré; F Giuntini; I M Eggleston; Michael Wilson; Alexander J MacRobert
Protoporphyrin IX enhancement by 5-aminolaevulinic acid peptide derivatives and the effect of RNA silencing on intracellular metabolism.
British journal of cancer 2009;100(5):723-31.
2008: Francesca Giuntini; Ludovic Bourré; Alexander J MacRobert; Michael Wilson; Ian M Eggleston
Quantitative determination of 5-aminolaevulinic acid and its esters in cell lysates by HPLC-fluorescence.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;875(2):562-6.
2008: Gabriela Di Venosa; Laura Hermida; Alcira Batlle; Haydée Fukuda; María Victoria Defain; Leandro Mamone; Lorena Rodriguez; Alexander J MacRobert; Adriana Casas
Characterisation of liposomes containing aminolevulinic acid and derived esters.
Journal of photochemistry and photobiology. B, Biology 2008;92(1):1-9.
2008: Ludovic Bourré; Francesca Giuntini; Ian M Eggleston; Michael Wilson; Alexander J MacRobert
5-Aminolaevulinic acid peptide prodrugs enhance photosensitization for photodynamic therapy.
Molecular cancer therapeutics 2008;7(6):1720-9.
2007: Lorena Rodriguez; Gabriela Divenosa; Alcira Batlle; Alexander J MacRobert; Adriana Casas
Response to ALA-based PDT in an immortalised normal breast cell line and its counterpart transformed with the Ras oncogene.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2007;6(12):1306-10.
2007: Josephine H Woodhams; Alexander J MacRobert; Stephen G Bown
The role of oxygen monitoring during photodynamic therapy and its potential for treatment dosimetry.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2007;6(12):1246-56.
2007: Lars Kunz; James P Connelly; Josephine H Woodhams; Alexander J MacRobert
Photodynamic modification of disulfonated aluminium phthalocyanine fluorescence in a macrophage cell line.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2007;6(9):940-8.
2007: D K Adigbli; D G G Wilson; N Farooqui; E Sousi; P Risley; Irving Taylor; Alexander J MacRobert; Marilena Loizidou
Photochemical internalisation of chemotherapy potentiates killing of multidrug-resistant breast and bladder cancer cells.
British journal of cancer 2007;97(4):502-12.
2007: Mark J Dixon; Ludovic Bourré; Alexander J MacRobert; Ian M Eggleston
Novel prodrug approach to photodynamic therapy: Fmoc solid-phase synthesis of a cell permeable peptide incorporating 5-aminolaevulinic acid.
Bioorganic & medicinal chemistry letters 2007;17(16):4518-22.
2007: Sinan Battah; Sherina Balaratnam; Adriana Casas; Sophie O'Neill; Christine Edwards; Alcira Batlle; Paul Dobbin; Alexander J MacRobert
Macromolecular delivery of 5-aminolaevulinic acid for photodynamic therapy using dendrimer conjugates.
Molecular cancer therapeutics 2007;6(3):876-85.
2007: Lakshmana Ayaru; Johannes Wittmann; Alexander J MacRobert; Marco Novelli; Stephen G Bown; Stephen P Pereira
Photodynamic therapy using verteporfin photosensitization in the pancreas and surrounding tissues in the Syrian golden hamster.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2007;7(1):20-7.
2006: Pei-Jen Lou; Ping-Shan Lai; Ming-Jium Shieh; Alexander J MacRobert; Kristian Berg; Stephen G Bown
Reversal of doxorubicin resistance in breast cancer cells by photochemical internalization.
International journal of cancer. Journal international du cancer 2006;119(11):2692-8.
2006: A Sharwani; Waseem Jerjes; Colin Hopper; Mark P Lewis; Mohammed El Maaytah; H S M Khalil; Alexander J MacRobert; Tahwinder Upile; Vehid Salih
Photodynamic therapy down-regulates the invasion promoting factors in human oral cancer.
Archives of oral biology 2006;51(12):1104-11.
2006: Gabriela Di Venosa; Alcira Batlle; Haydée Fukuda; Alexander J MacRobert; Adriana Casas
Distribution of 5-aminolevulinic acid derivatives and induced porphyrin kinetics in mice tissues.
Cancer chemotherapy and pharmacology 2006;58(4):478-86.
2006: Gabriela Di Venosa; Haydée Fukuda; Alcira Batlle; Alexander J MacRobert; Adriana Casas
Photodynamic therapy: regulation of porphyrin synthesis and hydrolysis from ALA esters.
Journal of photochemistry and photobiology. B, Biology 2006;83(2):129-36.
2006: A Sharwani; Waseem Jerjes; Vehid Salih; Alexander J MacRobert; Mohammed El Maaytah; H S M Khalil; Colin Hopper
Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy.
Journal of photochemistry and photobiology. B, Biology 2006;83(1):27-33.
2006: Alison Curnow; Alexander J MacRobert; Stephen G Bown
Comparing and combining light dose fractionation and iron chelation to enhance experimental photodynamic therapy with aminolevulinic acid.
Lasers in surgery and medicine 2006;38(4):325-31.
2006: Lorena Rodriguez; Alcira Batlle; Gabriela Di Venosa; Sinan Battah; Paul Dobbin; Alexander J MacRobert; Adriana Casas
Mechanisms of 5-aminolevulinic acid ester uptake in mammalian cells.
British journal of pharmacology 2006;147(7):825-33.
2006: Josephine H Woodhams; Alexander J MacRobert; Marco Novelli; Stephen G Bown
Photodynamic therapy with WST09 (Tookad): quantitative studies in normal colon and transplanted tumours.
International journal of cancer. Journal international du cancer 2006;118(2):477-82.
2006: Lorena Rodriguez; Alcira Batlle; Gabriela Di Venosa; Alexander J MacRobert; Sinan Battah; Hannelore Daniel; Adriana Casas
Study of the mechanisms of uptake of 5-aminolevulinic acid derivatives by PEPT1 and PEPT2 transporters as a tool to improve photodynamic therapy of tumours.
The international journal of biochemistry & cell biology 2006;38(9):1530-9.
2006: Nurgul Komerik; Alexander J MacRobert
Photodynamic therapy as an alternative antimicrobial modality for oral infections.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2006;25(1-2):487-504.
2006: Sinan Battah; Sophie O'Neill; Christine Edwards; Sherina Balaratnam; Paul Dobbin; Alexander J MacRobert
Enhanced porphyrin accumulation using dendritic derivatives of 5-aminolaevulinic acid for photodynamic therapy: an in vitro study.
The international journal of biochemistry & cell biology 2006;38(8):1382-92.
2006: Gabriela Di Venosa; Adriana Casas; Sinan Battah; Paul Dobbin; Haydée Fukuda; Alexander J MacRobert; Alcira Batlle
Investigation of a novel dendritic derivative of 5-aminolaevulinic acid for photodynamic therapy.
The international journal of biochemistry & cell biology 2006;38(1):82-91.
2005: Masahiko Harada; Josephine H Woodhams; Alexander J MacRobert; Mark R Feneley; Harubumi Kato; Stephen G Bown
The vascular response to photodynamic therapy with ATX-S10Na(II) in the normal rat colon.
Journal of photochemistry and photobiology. B, Biology 2005;79(3):223-30.
2004: Theodossis Theodossiou; Michael D Spiro; Jake Jacobson; John S Hothersall; Alexander J MacRobert
Evidence for intracellular aggregation of hypericin and the impact on its photocytotoxicity in PAM 212 murine keratinocytes.
Photochemistry and photobiology 2004;80(3):438-43.
2004: Josephine H Woodhams; Lars Kunz; Stephen G Bown; Alexander J MacRobert
Correlation of real-time haemoglobin oxygen saturation monitoring during photodynamic therapy with microvascular effects and tissue necrosis in normal rat liver.
British journal of cancer 2004;91(4):788-94.
2004: Christian Perotti; Haydée Fukuda; G DiVenosa; Alexander J MacRobert; Alcira Batlle; Adriana Casas
Porphyrin synthesis from ALA derivatives for photodynamic therapy. In vitro and in vivo studies.
British journal of cancer 2004;90(8):1660-5.
2003: Theodossis Theodossiou; John S Hothersall; Elizabeth A Woods; Klaus Okkenhaug; Jake Jacobson; Alexander J MacRobert
Firefly luciferin-activated rose bengal: in vitro photodynamic therapy by intracellular chemiluminescence in transgenic NIH 3T3 cells.
Cancer research 2003;63(8):1818-21.
2003: N Kömerik; H Nakanishi; Alexander J MacRobert; Brian Henderson; Paul M Speight; Michael Wilson
In vivo killing of Porphyromonas gingivalis by toluidine blue-mediated photosensitization in an animal model.
Antimicrobial agents and chemotherapy 2003;47(3):932-40.
2003: Josephine H Woodhams; Lars Kunz; Stephen G Bown; Alexander J MacRobert
Monitoring the effect of PDT on in vivo oxygen saturation and microvascular circulation.
Advances in experimental medicine and biology 2003;540():235-44.
2002: Theodossis Theodossiou; Alexander J MacRobert
Comparison of the photodynamic effect of exogenous photoprotoporphyrin and protoporphyrin IX on PAM 212 murine keratinocytes.
Photochemistry and photobiology 2002;76(5):530-7.
2002: Manpreet Bhatti; Alexander J MacRobert; Brian Henderson; Michael Wilson
Exposure of Porphyromonas gingivalis to red light in the presence of the light-activated antimicrobial agent toluidine blue decreases membrane fluidity.
Current microbiology 2002;45(2):118-22.
2002: H Tsutsui; Alexander J MacRobert; Alison Curnow; Agnieszka Rogowska; GA Buonaccorsi; H Kato; Stephen G Bown
Optimisation of illumination for photodynamic therapy with mTHPC on normal colon and a transplantable tumour in rats.
Lasers in medical science 2002;17(2):101-9.
2002: N Kömerik; Alison Curnow; Alexander J MacRobert; Colin Hopper; Paul M Speight; Michael Wilson
Fluorescence biodistribution and photosensitising activity of toluidine blue o on rat buccal mucosa.
Lasers in medical science 2002;17(2):86-92.
2002: Lars Kunz; Alexander J MacRobert
Intracellular photobleaching of 5,10,15,20-tetrakis(m-hydroxyphenyl) chlorin (Foscan) exhibits a complex dependence on oxygen level and fluence rate.
Photochemistry and photobiology 2002;75(1):28-35.
2001: Sinan Battah; C E Chee; H Nakanishi; S Gerscher; Alexander J MacRobert; Christine Edwards
Synthesis and biological studies of 5-aminolevulinic acid-containing dendrimers for photodynamic therapy.
Bioconjugate chemistry 2001;12(6):980-8.
2001: Manpreet Bhatti; Sean Nair; Alexander J MacRobert; Brian Henderson; philip shepherd; J Cridland; Michael Wilson
Identification of photolabile outer membrane proteins of Porphyromonas gingivalis.
Current microbiology 2001;43(2):96-9.
2001: S Gerscher; James P Connelly; Gerard M J Beijersbergen van Henegouwen; Alexander J MacRobert; P Watt; Lesley E Rhodes
A quantitative assessment of protoporphyrin IX metabolism and phototoxicity in human skin following dose-controlled delivery of the prodrugs 5-aminolaevulinic acid and 5-aminolaevulinic acid-n-pentylester.
The British journal of dermatology 2001;144(5):983-90.
2000: M A A Suhr; Colin Hopper; L Jones; J G George; Stephen G Bown; Alexander J MacRobert
Optical biopsy systems for the diagnosis and monitoring of superficial cancer and precancer.
International journal of oral and maxillofacial surgery 2000;29(6):453-7.
2000: S Gerscher; James P Connelly; J Griffiths; S B Brown; Alexander J MacRobert; G Wong; Lesley E Rhodes
Comparison of the pharmacokinetics and phototoxicity of protoporphyrin IX metabolized from 5-aminolevulinic acid and two derivatives in human skin in vivo.
Photochemistry and photobiology 2000;72(4):569-74.
2000: Manpreet Bhatti; Alexander J MacRobert; Brian Henderson; philip shepherd; J Cridland; Michael Wilson
Antibody-targeted lethal photosensitization of Porphyromonas gingivalis.
Antimicrobial agents and chemotherapy 2000;44(10):2615-8.
1999: Adriana Casas; Alcira Batlle; A R Butler; D Robertson; E H Brown; Alexander J MacRobert; P A Riley
Comparative effect of ALA derivatives on protoporphyrin IX production in human and rat skin organ cultures.
British journal of cancer 1999;80(10):1525-32.
1999: DI Fielding; GA Buonaccorsi; Alexander J MacRobert; A M Hanby; MR Hetzel; Stephen G Bown
Fine-needle interstitial photodynamic therapy of the lung parenchyma: photosensitizer distribution and morphologic effects of treatment.
Chest 1999;115(2):502-10.
1999: Alison Curnow; BW McIlroy; M J Postle-Hacon; Alexander J MacRobert; Stephen G Bown
Light dose fractionation to enhance photodynamic therapy using 5-aminolevulinic acid in the normal rat colon.
Photochemistry and photobiology 1999;69(1):71-6.
1998: Alison Curnow; BW McIlroy; M J Postle-Hacon; John B Porter; Alexander J MacRobert; Stephen G Bown
Enhancement of 5-aminolaevulinic acid-induced photodynamic therapy in normal rat colon using hydroxypyridinone iron-chelating agents.
British journal of cancer 1998;78(10):1278-82.
1998: MP Jenkins; GA Buonaccorsi; Alexander J MacRobert; C C R Bishop; Stephen G Bown; Jean R McEwan
Intra-arterial photodynamic therapy using 5-ALA in a swine model.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 1998;16(4):284-91.
1998: Manpreet Bhatti; Alexander J MacRobert; Sajeda Meghji; Brian Henderson; Michael Wilson
A study of the uptake of toluidine blue O by Porphyromonas gingivalis and the mechanism of lethal photosensitization.
Photochemistry and photobiology 1998;68(3):370-6.
1998: BW McIlroy; Alison Curnow; GA Buonaccorsi; M A Scott; Stephen G Bown; Alexander J MacRobert
Spatial measurement of oxygen levels during photodynamic therapy using time-resolved optical spectroscopy.
Journal of photochemistry and photobiology. B, Biology 1998;43(1):47-55.
1998: P Mĺkvy; H Messmann; J Regula; M Conio; M Pauer; C E Millson; Alexander J MacRobert; Stephen G Bown
Photodynamic therapy for gastrointestinal tumors using three photosensitizers--ALA induced PPIX, Photofrin and MTHPC. A pilot study.
Neoplasma 1998;45(3):157-61.
1997: SC Chang; GA Buonaccorsi; Alexander J MacRobert; Stephen G Bown
Interstitial photodynamic therapy in the canine prostate with disulfonated aluminum phthalocyanine and 5-aminolevulinic acid-induced protoporphyrin IX.
The Prostate 1997;32(2):89-98.
1997: Manpreet Bhatti; Alexander J MacRobert; Sajeda Meghji; Brian Henderson; Michael Wilson
Effect of dosimetric and physiological factors on the lethal photosensitization of Porphyromonas gingivalis in vitro.
Photochemistry and photobiology 1997;65(6):1026-31.
1997: SC Chang; Alexander J MacRobert; John B Porter; Stephen G Bown
The efficacy of an iron chelator (CP94) in increasing cellular protoporphyrin IX following intravesical 5-aminolaevulinic acid administration: an in vivo study.
Journal of photochemistry and photobiology. B, Biology 1997;38(2-3):114-22.
1997: P Mikvy; H Messman; Alexander J MacRobert; M Pauer; VR Sams; C L Davies; J C Stewart; Stephen G Bown
Photodynamic therapy of a transplanted pancreatic cancer model using meta-tetrahydroxyphenylchlorin (mTHPC).
British journal of cancer 1997;76(6):713-8.
1997: SC Chang; GA Buonaccorsi; Alexander J MacRobert; Stephen G Bown
5-Aminolevulinic acid (ALA)-induced protoporphyrin IX fluorescence and photodynamic effects in the rat bladder: an in vivo study comparing oral and intravesical ALA administration.
Lasers in surgery and medicine 1997;20(3):254-64.
1996: K F Fan; Colin Hopper; Paul M Speight; GA Buonaccorsi; Alexander J MacRobert; Stephen G Bown
Photodynamic therapy using 5-aminolevulinic acid for premalignant and malignant lesions of the oral cavity.
Cancer 1996;78(7):1374-83.
1996: S C Chang; GA Buonaccorsi; Alexander J MacRobert; Stephen G Bown
Interstitial and transurethral photodynamic therapy of the canine prostate using meso-tetra-(m-hydroxyphenyl) chlorin.
International journal of cancer. Journal international du cancer 1996;67(4):555-62.
1996: D Kleemann; Alexander J MacRobert; T Mentzel; Paul M Speight; Stephen G Bown
Photodynamic therapy on the normal rabbit larynx with phthalocyanine and 5-aminolaevulinic acid induced protoporphyrin IX photosensitisation.
British journal of cancer 1996;74(1):49-58.
1996: P Mlkvy; Helmut Messmann; M Pauer; J C Stewart; C E Millson; Alexander J MacRobert; Stephen G Bown
Distribution and photodynamic effects of meso-tetrahydroxyphenylchlorin (mTHPC) in the pancreas and adjacent tissues in the Syrian golden hamster.
British journal of cancer 1996;73(12):1473-9.
1996: S C Chang; Alexander J MacRobert; Stephen G Bown
Photodynamic therapy on rat urinary bladder with intravesical instillation of 5-aminolevulinic acid: light diffusion and histological changes.
The Journal of urology 1996;155(5):1749-53.
1996: S C Chang; Alexander J MacRobert; Stephen G Bown
Biodistribution of protoporphyrin IX in rat urinary bladder after intravesical instillation of 5-aminolevulinic acid.
The Journal of urology 1996;155(5):1744-8.
1996: C E Millson; Michael Wilson; Alexander J MacRobert; J Bedwell; Stephen G Bown
The killing of Helicobacter pylori by low-power laser light in the presence of a photosensitiser.
Journal of medical microbiology 1996;44(4):245-52.
1996: C L Davies; P M Duffy; Alexander J MacRobert; Marilena Loizidou; Alan J Cooper; Irving Taylor
Localization of anthracycline accumulation in sensitive and resistant urothelial tumor cell lines.
Cancer detection and prevention 1996;20(6):625-33.
1996: C E Millson; Michael Wilson; Alexander J MacRobert; Stephen G Bown
Ex-vivo treatment of gastric Helicobacter infection by photodynamic therapy.
Journal of photochemistry and photobiology. B, Biology 1996;32(1-2):59-65.
1996: C S Loh; Alexander J MacRobert; GA Buonaccorsi; N Krasner; Stephen G Bown
Mucosal ablation using photodynamic therapy for the treatment of dysplasia: an experimental study in the normal rat stomach.
Gut 1996;38(1):71-8.
1996: I Nyamekye; GA Buonaccorsi; Jean R McEwan; Alexander J MacRobert; Stephen G Bown; C Bishop
Inhibition of intimal hyperplasia in balloon injured arteries with adjunctive phthalocyanine sensitised photodynamic therapy.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 1996;11(1):19-28.
1995: Helmut Messmann; P Mlkvy; GA Buonaccorsi; C L Davies; Alexander J MacRobert; Stephen G Bown
Enhancement of photodynamic therapy with 5-aminolaevulinic acid-induced porphyrin photosensitisation in normal rat colon by threshold and light fractionation studies.
British journal of cancer 1995;72(3):589-94.
1995: W E Grant; GA Buonaccorsi; Paul M Speight; Alexander J MacRobert; Colin Hopper; Stephen G Bown
The effect of photodynamic therapy on the mechanical integrity of normal rabbit carotid arteries.
The Laryngoscope 1995;105(8 Pt 1):867-71.
1995: P Mlkvy; Helmut Messmann; H Debinski; J Regula; M Conio; Alexander J MacRobert; A Spigelman; R Phillips; Stephen G Bown
Photodynamic therapy for polyps in familial adenomatous polyposis--a pilot study.
European journal of cancer (Oxford, England : 1990) 1995;31A(7-8):1160-5.
1995: K Anson; GA Buonaccorsi; M Eddowes; Alexander J MacRobert; T Mills; G Watson
A comparative optical analysis of laser side-firing devices: a guide to treatment.
British journal of urology 1995;75(3):328-34.
1995: I Nyamekye; S Anglin; Jean R McEwan; Alexander J MacRobert; Stephen G Bown; C Bishop
Photodynamic therapy of normal and balloon-injured rat carotid arteries using 5-amino-levulinic acid.
Circulation 1995;91(2):417-25.
1995: J Regula; Alexander J MacRobert; A Gorchein; GA Buonaccorsi; S M Thorpe; G M Spencer; A R Hatfield; Stephen G Bown
Photosensitisation and photodynamic therapy of oesophageal, duodenal, and colorectal tumours using 5 aminolaevulinic acid induced protoporphyrin IX--a pilot study.
Gut 1995;36(1):67-75.
1995: D Kleemann; Alexander J MacRobert; T Mentzel; S G Brown
Experimental photodynamic therapy of the larynx using 5-aminolaevulinic acid.
Advances in oto-rhino-laryngology 1995;49():36-8.
1995: P Mĺkvy; Helmut Messmann; J Regula; M Conio; M Pauer; C E Millson; Alexander J MacRobert; Stephen G Bown
Sensitization and photodynamic therapy (PDT) of gastrointestinal tumors with 5-aminolaevulinic acid (ALA) induced protoporphyrin IX (PPIX). A pilot study.
Neoplasma 1995;42(3):109-13.
1994: J Regula; B Ravi; J Bedwell; Alexander J MacRobert; Stephen G Bown
Photodynamic therapy using 5-aminolaevulinic acid for experimental pancreatic cancer--prolonged animal survival.
British journal of cancer 1994;70(2):248-54.
1994: W E Grant; Paul M Speight; Alexander J MacRobert; Colin Hopper; Stephen G Bown
Photodynamic therapy of normal rat arteries after photosensitisation using disulphonated aluminium phthalocyanine and 5-aminolaevulinic acid.
British journal of cancer 1994;70(1):72-8.
1993: W E Grant; Colin Hopper; Paul M Speight; Alexander J MacRobert; Stephen G Bown
Photodynamic therapy of malignant and premalignant lesions in patients with 'field cancerization' of the oral cavity.
The Journal of laryngology and otology 1993;107(12):1140-5.
1993: C S Loh; D Vernon; Alexander J MacRobert; J Bedwell; Stephen G Bown; S B Brown
Endogenous porphyrin distribution induced by 5-aminolaevulinic acid in the tissue layers of the gastrointestinal tract.
Journal of photochemistry and photobiology. B, Biology 1993;20(1):47-54.
1993: W E Grant; Colin Hopper; Alexander J MacRobert; Paul M Speight; Stephen G Bown
Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid.
Lancet 1993;342(8864):147-8.
1993: C S Loh; Alexander J MacRobert; J Bedwell; J Regula; N Krasner; Stephen G Bown
Oral versus intravenous administration of 5-aminolaevulinic acid for photodynamic therapy.
British journal of cancer 1993;68(1):41-51.
1993: S G Smith; J Bedwell; Alexander J MacRobert; M H Griffiths; Stephen G Bown; M R Hetzel
Experimental studies to assess the potential of photodynamic therapy for the treatment of bronchial carcinomas.
Thorax 1993;48(5):474-80.
1992: J C Bremner; GE Adams; J K Pearson; J M Sansom; Ian J Stratford; J Bedwell; Stephen G Bown; Alexander J MacRobert; D Phillips
Increasing the effect of photodynamic therapy on the RIF-1 murine sarcoma, using the bioreductive drugs RSU1069 and RB6145.
British journal of cancer 1992;66(6):1070-6.
1992: C S Loh; J Bedwell; Alexander J MacRobert; N Krasner; D Phillips; Stephen G Bown
Photodynamic therapy of the normal rat stomach: a comparative study between di-sulphonated aluminium phthalocyanine and 5-aminolaevulinic acid.
British journal of cancer 1992;66(3):452-62.
1992: P T Chatlani; P J Nuutinen; N Toda; Hugh Barr; Alexander J MacRobert; J Bedwell; Stephen G Bown
Selective necrosis in hamster pancreatic tumours using photodynamic therapy with phthalocyanine photosensitization.
The British journal of surgery 1992;79(8):786-90.
1992: J Bedwell; Alexander J MacRobert; D Phillips; Stephen G Bown
Fluorescence distribution and photodynamic effect of ALA-induced PP IX in the DMH rat colonic tumour model.
British journal of cancer 1992;65(6):818-24.
1992: J Morgan; Alexander J MacRobert; A G Gray; E R Huehns
Use of photosensitive, antibody directed liposomes to destroy target populations of cells in bone marrow: a potential purging method for autologous bone marrow transplantation.
British journal of cancer 1992;65(1):58-64.
1991: P J Nuutinen; P T Chatlani; J Bedwell; Alexander J MacRobert; D Phillips; Stephen G Bown
Distribution and photodynamic effect of disulphonated aluminium phthalocyanine in the pancreas and adjacent tissues in the Syrian golden hamster.
British journal of cancer 1991;64(6):1108-15.
1991: P T Chatlani; J Bedwell; Alexander J MacRobert; Hugh Barr; Paul B Boulos; N Krasner; D Phillips; Stephen G Bown
Comparison of distribution and photodynamic effects of di- and tetra-sulphonated aluminium phthalocyanines in normal rat colon.
Photochemistry and photobiology 1991;53(6):745-51.
1991: J Bedwell; P T Chatlani; Alexander J MacRobert; J E Roberts; Hugh Barr; J Dillon; Stephen G Bown
Enhanced tumour selectivity of photodynamic therapy in the rat colon using a radioprotective agent.
Photochemistry and photobiology 1991;53(6):753-6.
1991: Hugh Barr; P Chatlani; C J Tralau; Alexander J MacRobert; Paul B Boulos; Stephen G Bown
Local eradication of rat colon cancer with photodynamic therapy: correlation of distribution of photosensitiser with biological effects in normal and tumour tissue.
Gut 1991;32(5):517-23.
1990: Hugh Barr; Alexander J MacRobert; C J Tralau; Paul B Boulos; Stephen G Bown
The significance of the nature of the photosensitizer for photodynamic therapy: quantitative and biological studies in the colon.
British journal of cancer 1990;62(5):730-5.
1990: Hugh Barr; C J Tralau; Paul B Boulos; Alexander J MacRobert; N Krasner; D Phillips; Stephen G Bown
Selective necrosis in dimethylhydrazine-induced rat colon tumors using phthalocyanine photodynamic therapy.
Gastroenterology 1990;98(6):1532-7.
1990: J Bedwell; john holton; D Vaira; Alexander J MacRobert; Stephen G Bown
In vitro killing of Helicobacter pylori with photodynamic therapy.
Lancet 1990;335(8700):1287.
1989: C J Tralau; A R Young; N P Walker; D I Vernon; Alexander J MacRobert; S B Brown; Stephen G Bown
Mouse skin photosensitivity with dihaematoporphyrin ether (DHE) and aluminium sulphonated phthalocyanine (AlSPc): a comparative study.
Photochemistry and photobiology 1989;49(3):305-12.
1987: Hugh Barr; C J Tralau; Paul B Boulos; Alexander J MacRobert; R Tilly; Stephen G Bown
The contrasting mechanisms of colonic collagen damage between photodynamic therapy and thermal injury.
Photochemistry and photobiology 1987;46(5):795-800.
1987: Hugh Barr; C J Tralau; Alexander J MacRobert; N Krasner; Paul B Boulos; C G Clark; Stephen G Bown
Photodynamic therapy in the normal rat colon with phthalocyanine sensitisation.
British journal of cancer 1987;56(2):111-8.
1987: C J Tralau; Alexander J MacRobert; P D Coleridge-Smith; Hugh Barr; Stephen G Bown
Photodynamic therapy with phthalocyanine sensitisation: quantitative studies in a transplantable rat fibrosarcoma.
British journal of cancer 1987;55(4):389-95.