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James Madara

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James L Madara
Commentary: getting real on addressing health care disparities and other systems problems.
Diane Lawson Martinez; Jerry S Trier; James L Madara; Thomas J Layden
Our new president--Gail A. Hecht, MD, MS.
Martin E Feder; James L Madara
Evidence-based appointment and promotion of academic faculty at the University of Chicago.

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All Publications

2012: James L Madara
Commentary: getting real on addressing health care disparities and other systems problems.
Academic medicine : journal of the Association of American Medical Colleges 2012;87(6):687-8.
2009: Diane Lawson Martinez; Jerry S Trier; James L Madara; Thomas J Layden
Our new president--Gail A. Hecht, MD, MS.
Gastroenterology 2009;136(5):1821-6.
2008: Martin E Feder; James L Madara
Evidence-based appointment and promotion of academic faculty at the University of Chicago.
Academic medicine : journal of the Association of American Medical Colleges 2008;83(1):85-95.
2007: holly humphrey; Kelly Smith; Shalini Reddy; Don Scott; James L Madara; Vineet M Arora
Promoting an environment of professionalism: the University of Chicago "Roadmap".
Academic medicine : journal of the Association of American Medical Colleges 2007;82(11):1098-107.
2007: Frances L Szeto; Jun Sun; Juan Kong; Yingli Duan; Anne Liao; James L Madara; chen yunzi
Involvement of the vitamin D receptor in the regulation of NF-kappaB activity in fibroblasts.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):563-6.
2007: Jun Sun; Pamela E Fegan; Anjali S Desai; James L Madara; Michael E Hobert
Flagellin-induced tolerance of the Toll-like receptor 5 signaling pathway in polarized intestinal epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(3):G767-78.
2006: Jun Sun; Juan Kong; Yingli Duan; Frances L Szeto; Anne Liao; James L Madara; chen yunzi
Increased NF-kappaB activity in fibroblasts lacking the vitamin D receptor.
American journal of physiology. Endocrinology and metabolism 2006;291(2):E315-22.
2005: Robert W McKenna; Diane D Davey; Rebecca L Johnson; David Keren; James L Madara; Sharon W Weiss; Betsy D Bennett
Maintenance of certification for pathologists: what we know so far.
American journal of clinical pathology 2005;124 Suppl():S5-7.
2005: Laurence D Hill; James L Madara
Role of the urban academic medical center in US health care.
JAMA : the journal of the American Medical Association 2005;294(17):2219-20.
2005: Torsten Kucharzik; James T Hudson; Andreas Lügering; J A Abbas; Matthew Bettini; J G Lake; Mary E Evans; Thomas R Ziegler; Didier Merlin; James L Madara; Ifor Williams
Acute induction of human IL-8 production by intestinal epithelium triggers neutrophil infiltration without mucosal injury.
Gut 2005;54(11):1565-72.
2005: Jun Sun; Michael E Hobert; Yingli Duan; Anjali S Rao; Tong-Chuan He; Eugene B Chang; James L Madara
Crosstalk between NF-kappaB and beta-catenin pathways in bacterial-colonized intestinal epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(1):G129-37.
2004: Matthias Bruewer; Ann M Hopkins; Michael E Hobert; Asma Nusrat; James L Madara
RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin.
American journal of physiology. Cell physiology 2004;287(2):C327-35.
2004: Jun Sun; Michael E Hobert; Anjali S Rao; Andrew S Neish; James L Madara
Bacterial activation of beta-catenin signaling in human epithelia.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(1):G220-7.
2004: Randall J Mrsny; Andrew T Gewirtz; Dario Siccardi; Tor C Savidge; Bryan P Hurley; James L Madara; Beth A McCormick
Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7421-6.
2004: Patricia W Lin; Peter O Simon; Andrew T Gewirtz; Andrew S Neish; Andre J Ouellette; James L Madara; Wayne I Lencer
Paneth cell cryptdins act in vitro as apical paracrine regulators of the innate inflammatory response.
The Journal of biological chemistry 2004;279(19):19902-7.
2003: Matthias Bruewer; Andreas Luegering; Torsten Kucharzik; Charles A Parkos; James L Madara; Ann M Hopkins; Asma Nusrat
Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):6164-72.
2003: Hui Zeng; Adam Q Carlson; Yanwen Guo; Yimin Yu; Lauren S Collier-Hyams; James L Madara; Andrew T Gewirtz; Andrew S Neish
Flagellin is the major proinflammatory determinant of enteropathogenic Salmonella.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(7):3668-74.
2003: Torsten Kucharzik; Andrew T Gewirtz; Didier Merlin; James L Madara; Ifor Williams
Lateral membrane LXA4 receptors mediate LXA4's anti-inflammatory actions on intestinal epithelium.
American journal of physiology. Cell physiology 2003;284(4):C888-96.
2002: Michael E Hobert; Kara A Sands; Randall J Mrsny; James L Madara
Cdc42 and Rac1 regulate late events in Salmonella typhimurium-induced interleukin-8 secretion from polarized epithelial cells.
The Journal of biological chemistry 2002;277(52):51025-32.
2002: Andrew T Gewirtz; Yuan Liu; Shanthi V Sitaraman; James L Madara
Intestinal epithelial pathobiology: past, present and future.
Best practice & research. Clinical gastroenterology 2002;16(6):851-67.
2002: Lauren S Collier-Hyams; Hui Zeng; Jun Sun; Amelia D Tomlinson; Zhao Qin Bao; Huaqun Chen; James L Madara; Kim Orth; Andrew S Neish
Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):2846-50.
2002: Shanthi V Sitaraman; Lixin Wang; Michelle Wong; Matthias Bruewer; Michael E Hobert; C-H Yun; Didier Merlin; James L Madara
The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulation.
The Journal of biological chemistry 2002;277(36):33188-95.
2002: Andrew T Gewirtz; Lauren S Collier-Hyams; Andrew N Young; Torsten Kucharzik; William J Guilford; John Parkinson; Ifor Williams; Andrew S Neish; James L Madara
Lipoxin a4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5260-7.
2002: Gang Yue; Didier Merlin; Michael Selsted; Wayne I Lencer; James L Madara; Douglas C. Eaton
Cryptdin 3 forms anion selective channels in cytoplasmic membranes of human embryonic kidney cells.
American journal of physiology. Gastrointestinal and liver physiology 2002;282(5):G757-65.
2002: Katharine A Reed; Michael E Hobert; Claire E Kolenda; Kara A Sands; Michelle B. Rathman; Miriam O'Connor; Sean Lyons; Andrew T Gewirtz; Philippe J Sansonetti; James L Madara
The Salmonella typhimurium flagellar basal body protein FliE is required for flagellin production and to induce a proinflammatory response in epithelial cells.
The Journal of biological chemistry 2002;277(15):13346-53.
2002: Andrew T Gewirtz; Andrew S Neish; James L Madara
Mechanisms of active intestinal inflammation and potential down-regulation via lipoxins.
Advances in experimental medicine and biology 2002;507():229-36.
2001: Yuan Liu; Didier Merlin; S L Burst; Mildred M Pochet; James L Madara; Charles A Parkos
The role of CD47 in neutrophil transmigration. Increased rate of migration correlates with increased cell surface expression of CD47.
The Journal of biological chemistry 2001;276(43):40156-66.
2001: Didier Merlin; Shanthi V Sitaraman; Xia Liu; Karen Eastburn; Jun Sun; Torsten Kucharzik; B Lewis; James L Madara
CD98-mediated links between amino acid transport and beta 1 integrin distribution in polarized columnar epithelia.
The Journal of biological chemistry 2001;276(42):39282-9.
2001: Andrew T Gewirtz; T A Navas; Sean Lyons; Paul J Godowski; James L Madara
Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):1882-5.
2001: Didier Merlin; M Si-Tahar; Shanthi V Sitaraman; Karen Eastburn; Ifor Williams; Xia Liu; M A Hediger; James L Madara
Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: transport of bacterial peptides influences expression of MHC class 1 molecules.
Gastroenterology 2001;120(7):1666-79.
2001: Shanthi V Sitaraman; Didier Merlin; Lixin Wang; M Wong; Andrew T Gewirtz; M Si-Tahar; James L Madara
Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6.
The Journal of clinical investigation 2001;107(7):861-9.
2001: Titus A. Reaves; S P Colgan; Periasamy Selvaraj; Mildred M Pochet; Shaun Walsh; Asma Nusrat; Tony Liang; James L Madara; Charles A Parkos
Neutrophil transepithelial migration: regulation at the apical epithelial surface by Fc-mediated events.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(4):G746-54.
2001: Asma Nusrat; C von Eichel-Streiber; Jerrold R Turner; Paul Verkade; James L Madara; Charles A Parkos
Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins.
Infection and immunity 2001;69(3):1329-36.
2001: M Si-Tahar; Shanthi V Sitaraman; T Shibahara; James L Madara
Negative regulation of epithelium-neutrophil interactions via activation of CD44.
American journal of physiology. Cell physiology 2001;280(3):C423-32.
2001: Didier Merlin; Gang Yue; Wayne I Lencer; Michael Selsted; James L Madara
Cryptdin-3 induces novel apical conductance(s) in Cl- secretory, including cystic fibrosis, epithelia.
American journal of physiology. Cell physiology 2001;280(2):C296-302.
2001: T Shibahara; Josiah N Wilcox; Tracey L Couse; James L Madara
Characterization of epithelial chemoattractants for human intestinal intraepithelial lymphocytes.
Gastroenterology 2001;120(1):60-70.
2001: Andrew T Gewirtz; Peter O Simon; Clare K Schmitt; L J Taylor; Curt H Hagedorn; Alison D O'Brien; Andrew S Neish; James L Madara
Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response.
The Journal of clinical investigation 2001;107(1):99-109.
2000: Jerrold R Turner; Eric D Black; J Ward; Chung-Ming Tse; F A Uchwat; H A Alli; Mark Donowitz; James L Madara; J M Angle
Transepithelial resistance can be regulated by the intestinal brush-border Na(+)/H(+) exchanger NHE3.
American journal of physiology. Cell physiology 2000;279(6):C1918-24.
2000: Jerrold R Turner; D E Cohen; Randall J Mrsny; James L Madara
Noninvasive in vivo analysis of human small intestinal paracellular absorption: regulation by Na+-glucose cotransport.
Digestive diseases and sciences 2000;45(11):2122-6.
2000: Asma Nusrat; Jerrold R Turner; James L Madara
Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(5):G851-7.
2000: Andrew S Neish; Andrew T Gewirtz; Hui Zeng; Andrew N Young; Michael E Hobert; V Karmali; Anjali S Rao; James L Madara
Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination.
Science (New York, N.Y.) 2000;289(5484):1560-3.
2000: James L Madara
Modulation of tight junctional permeability.
Advanced drug delivery reviews 2000;41(3):251-3.
2000: Shanthi V Sitaraman; M Si-Tahar; Didier Merlin; GR Strohmeier; James L Madara
Polarity of A2b adenosine receptor expression determines characteristics of receptor desensitization.
American journal of physiology. Cell physiology 2000;278(6):C1230-6.
2000: M Si-Tahar; Didier Merlin; Shanthi V Sitaraman; James L Madara
Constitutive and regulated secretion of secretory leukocyte proteinase inhibitor by human intestinal epithelial cells.
Gastroenterology 2000;118(6):1061-71.
2000: Asma Nusrat; Charles A Parkos; Paul Verkade; C S Foley; Tony Liang; W Innis-Whitehouse; Karen Eastburn; James L Madara
Tight junctions are membrane microdomains.
Journal of cell science 2000;113 ( Pt 10)():1771-81.
2000: T Shibahara; M Si-Tahar; Sunil K Shaw; James L Madara
Adhesion molecules expressed on homing lymphocytes in model intestinal epithelia.
Gastroenterology 2000;118(2):289-98.
2000: Andrew T Gewirtz; James L Madara
Lipoxin-stable analogs: potential therapeutic downregulators of intestinal inflammation.
Ernst Schering Research Foundation workshop 2000;(31):187-99.
2000: Andrew T Gewirtz; Anjali S Rao; Peter O Simon; Didier Merlin; D Carnes; James L Madara; Andrew S Neish
Salmonella typhimurium induces epithelial IL-8 expression via Ca(2+)-mediated activation of the NF-kappaB pathway.
The Journal of clinical investigation 2000;105(1):79-92.
1999: Jerrold R Turner; J M Angle; Eric D Black; JL Joyal; David B Sacks; James L Madara
PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase.
The American journal of physiology 1999;277(3 Pt 1):C554-62.
1999: James L Madara; M C Carey
Presentation of the Julius M. Friedenwald medal to Jerry S. Trier, M.D.
Gastroenterology 1999;116(6):1457-61.
1999: Andrew T Gewirtz; Valery V Fokin; Nicos A Petasis; Charles N Serhan; James L Madara
LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation.
The American journal of physiology 1999;276(4 Pt 1):C988-94.
1999: Andrew T Gewirtz; AM Siber; James L Madara; Beth A McCormick
Orchestration of neutrophil movement by intestinal epithelial cells in response to Salmonella typhimurium can be uncoupled from bacterial internalization.
Infection and immunity 1999;67(2):608-17.
1998: Didier Merlin; A Steel; Andrew T Gewirtz; M Si-Tahar; M A Hediger; James L Madara
hPepT1-mediated epithelial transport of bacteria-derived chemotactic peptides enhances neutrophil-epithelial interactions.
The Journal of clinical investigation 1998;102(11):2011-8.
1998: Sunil K Shaw; A Hermanowski-Vosatka; T Shibahara; Beth A McCormick; Charles A Parkos; SL Carlson; E C Ebert; M B Brenner; James L Madara
Migration of intestinal intraepithelial lymphocytes into a polarized epithelial monolayer.
The American journal of physiology 1998;275(3 Pt 1):G584-91.
1998: Didier Merlin; L Jiang; GR Strohmeier; Asma Nusrat; S L Alper; Wayne I Lencer; James L Madara
Distinct Ca2+- and cAMP-dependent anion conductances in the apical membrane of polarized T84 cells.
The American journal of physiology 1998;275(2 Pt 1):C484-95.
1998: Anne A Wolf; Michael G Jobling; S Wimer-Mackin; M Ferguson-Maltzman; James L Madara; Randall K Holmes; Wayne I Lencer
Ganglioside structure dictates signal transduction by cholera toxin and association with caveolae-like membrane domains in polarized epithelia.
The Journal of cell biology 1998;141(4):917-27.
1998: Andrew T Gewirtz; B McCormick; Andrew S Neish; Nicos A Petasis; Karsten Gronert; Charles N Serhan; James L Madara
Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs.
The Journal of clinical investigation 1998;101(9):1860-9.
1998: Karsten Gronert; Andrew T Gewirtz; James L Madara; Charles N Serhan
Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release.
The Journal of experimental medicine 1998;187(8):1285-94.
1998: James L Madara
Regulation of the movement of solutes across tight junctions.
Annual review of physiology 1998;60():143-59.
1998: Beth A McCormick; Charles A Parkos; S P Colgan; D K Carnes; James L Madara
Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):455-66.
1997: James L Madara
Review article: Pathobiology of neutrophil interactions with intestinal epithelia.
Alimentary pharmacology & therapeutics 1997;11 Suppl 3():57-62; discussion 62-3.
1997: Asma Nusrat; Charles A Parkos; Tony Liang; D K Carnes; James L Madara
Neutrophil migration across model intestinal epithelia: monolayer disruption and subsequent events in epithelial repair.
Gastroenterology 1997;113(5):1489-500.
1997: Jerrold R Turner; B K Rill; SL Carlson; D Carnes; R Kerner; Randall J Mrsny; James L Madara
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation.
The American journal of physiology 1997;273(4 Pt 1):C1378-85.
1997: James L Madara
The chameleon within: improving antigen delivery.
Science (New York, N.Y.) 1997;277(5328):910-1.
1997: Wayne I Lencer; G Cheung; GR Strohmeier; M G Currie; Andre J Ouellette; Michael Selsted; James L Madara
Induction of epithelial chloride secretion by channel-forming cryptdins 2 and 3.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(16):8585-9.
1997: Wayne I Lencer; C Constable; S Moe; Paul A Rufo; A Wolf; Michael G Jobling; S P Ruston; James L Madara; Randall K Holmes; Timothy R Hirst
Proteolytic activation of cholera toxin and Escherichia coli labile toxin by entry into host epithelial cells. Signal transduction by a protease-resistant toxin variant.
The Journal of biological chemistry 1997;272(24):15562-8.
1997: GR Strohmeier; Wayne I Lencer; T W Patapoff; L F Thompson; SL Carlson; S J Moe; D K Carnes; Randall J Mrsny; James L Madara
Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia.
The Journal of clinical investigation 1997;99(11):2588-601.
1997: Beth A McCormick; Asma Nusrat; Charles A Parkos; L D'Andrea; P M Hofman; D Carnes; Tony Liang; James L Madara
Unmasking of intestinal epithelial lateral membrane beta1 integrin consequent to transepithelial neutrophil migration in vitro facilitates inv-mediated invasion by Yersinia pseudotuberculosis.
Infection and immunity 1997;65(4):1414-21.
1996: L D'Andrea; C Lytle; Jeffrey B Matthews; P Hofman; Biff Forbush; James L Madara
Na:K:2Cl cotransporter (NKCC) of intestinal epithelial cells. Surface expression in response to cAMP.
The Journal of biological chemistry 1996;271(46):28969-76.
1996: Charles A Parkos; Sean P Colgan; M S Diamond; Asma Nusrat; Tony Liang; Timothy A Springer; James L Madara
Expression and polarization of intercellular adhesion molecule-1 on human intestinal epithelia: consequences for CD11b/CD18-mediated interactions with neutrophils.
Molecular medicine (Cambridge, Mass.) 1996;2(4):489-505.
1996: P Hofman; L D'Andrea; D Carnes; Sean P Colgan; James L Madara
Intestinal epithelial cytoskeleton selectively constrains lumen-to-tissue migration of neutrophils.
The American journal of physiology 1996;271(1 Pt 1):C312-20.
1996: Sean P Colgan; Victor Morales; James L Madara; J E Polischuk; S P Balk; Richard S Blumberg
IFN-gamma modulates CD1d surface expression on intestinal epithelia.
The American journal of physiology 1996;271(1 Pt 1):C276-83.
1996: Jerrold R Turner; Wayne I Lencer; S Carlson; James L Madara
Carboxy-terminal vesicular stomatitis virus G protein-tagged intestinal Na+-dependent glucose cotransporter (SGLT1): maintenance of surface expression and global transport function with selective perturbation of transport kinetics and polarized expression.
The Journal of biological chemistry 1996;271(13):7738-44.
1996: G Zünd; James L Madara; AL Dzus; C S Awtrey; Sean P Colgan
Interleukin-4 and interleukin-13 differentially regulate epithelial chloride secretion.
The Journal of biological chemistry 1996;271(13):7460-4.
1996: Charles A Parkos; Sean P Colgan; Tony Liang; Asma Nusrat; A E Bacarra; D K Carnes; James L Madara
CD47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epithelia.
The Journal of cell biology 1996;132(3):437-50.
1996: Beth A McCormick; S I Miller; James L Madara
New insights on molecular pathways utilized by salmonella species in cell binding.
Frontiers in bioscience : a journal and virtual library 1996;1():d131-45.
1995: Beth A McCormick; P M Hofman; J Kim; D K Carnes; S I Miller; James L Madara
Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils.
The Journal of cell biology 1995;131(6 Pt 1):1599-608.
1995: Charles N Serhan; J F Maddox; Nicos A Petasis; I Akritopoulou-Zanze; A Papayianni; Hugh R Brady; Sean P Colgan; James L Madara
Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils.
Biochemistry 1995;34(44):14609-15.
1995: Asma Nusrat; M Giry; Jerrold R Turner; Sean P Colgan; Charles A Parkos; D Carnes; emmanuel lemichez; Patrice Boquet; James L Madara
Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10629-33.
1995: Wayne I Lencer; C Constable; S Moe; Michael G Jobling; H M Webb; S Ruston; James L Madara; Timothy R Hirst; Randall K Holmes
Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL.
The Journal of cell biology 1995;131(4):951-62.
1995: Wayne I Lencer; S Moe; Paul A Rufo; James L Madara
Transcytosis of cholera toxin subunits across model human intestinal epithelia.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10094-8.
1995: Wayne I Lencer; GR Strohmeier; S Moe; S L Carlson; C T Constable; James L Madara
Signal transduction by cholera toxin: processing in vesicular compartments does not require acidification.
The American journal of physiology 1995;269(4 Pt 1):G548-57.
1995: Beth A McCormick; S I Miller; D Carnes; James L Madara
Transepithelial signaling to neutrophils by salmonellae: a novel virulence mechanism for gastroenteritis.
Infection and immunity 1995;63(6):2302-9.
1995: Sean P Colgan; Charles A Parkos; D McGuirk; Hugh R Brady; A A Papayianni; G Frendl; James L Madara
Receptors involved in carbohydrate binding modulate intestinal epithelial-neutrophil interactions.
The Journal of biological chemistry 1995;270(18):10531-9.
1995: GR Strohmeier; S M Reppert; Wayne I Lencer; James L Madara
The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia.
The Journal of biological chemistry 1995;270(5):2387-94.
1995: M B Resnick; Sean P Colgan; Charles A Parkos; C Delp-Archer; D McGuirk; Peter Weller; James L Madara
Human eosinophils migrate across an intestinal epithelium in response to platelet-activating factor.
Gastroenterology 1995;108(2):409-16.
1995: Charles A Parkos; Sean P Colgan; A E Bacarra; Asma Nusrat; C Delp-Archer; S Carlson; D H Su; James L Madara
Intestinal epithelia (T84) possess basolateral ligands for CD11b/CD18-mediated neutrophil adherence.
The American journal of physiology 1995;268(2 Pt 1):C472-9.
1995: S E Sanders; James L Madara; D K McGuirk; D S Gelman; Sean P Colgan
Assessment of inflammatory events in epithelial permeability: a rapid screening method using fluorescein dextrans.
Epithelial cell biology 1995;4(1):25-34.
1995: Asma Nusrat; James L Madara
Modulation of intercellular junctions of epithelia by scatter factor (hepatocyte growth factor).
EXS 1995;74():69-87.
1994: Sean P Colgan; M B Resnick; Charles A Parkos; C Delp-Archer; D McGuirk; A E Bacarra; Peter Weller; James L Madara
IL-4 directly modulates function of a model human intestinal epithelium.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(5):2122-9.
1994: Sean P Colgan; Charles A Parkos; Jeffrey B Matthews; L D'Andrea; C S Awtrey; A H Lichtman; C Delp-Archer; James L Madara
Interferon-gamma induces a cell surface phenotype switch on T84 intestinal epithelial cells.
The American journal of physiology 1994;267(2 Pt 1):C402-10.
1994: P Kaoutzani; Sean P Colgan; K L Cepek; P G Burkard; S Carlson; C Delp-Archer; Michael B Brenner; James L Madara
Reconstitution of cultured intestinal epithelial monolayers with a mucosal-derived T lymphocyte cell line. Modulation of epithelial phenotype dependent on lymphocyte-basolateral membrane apposition.
The Journal of clinical investigation 1994;94(2):788-96.
1994: Jeffrey B Matthews; J A Smith; K J Tally; C S Awtrey; H Nguyen; J Rich; James L Madara
Na-K-2Cl cotransport in intestinal epithelial cells. Influence of chloride efflux and F-actin on regulation of cotransporter activity and bumetanide binding.
The Journal of biological chemistry 1994;269(22):15703-9.
1994: R Moore; James L Madara; R J MacLeod
Enterocytes adhere preferentially to collagen IV in a differentially regulated divalent cation-dependent manner.
The American journal of physiology 1994;266(6 Pt 1):G1099-107.
1994: Asma Nusrat; Charles A Parkos; A E Bacarra; P J Godowski; C Delp-Archer; E M Rosen; James L Madara
Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and induction of rapid wound repair in a transformed model epithelium.
The Journal of clinical investigation 1994;93(5):2056-65.
1993: Wayne I Lencer; J B de Almeida; S Moe; J L Stow; Dennis A Ausiello; James L Madara
Entry of cholera toxin into polarized human intestinal epithelial cells. Identification of an early brefeldin A sensitive event required for A1-peptide generation.
The Journal of clinical investigation 1993;92(6):2941-51.
1993: M B Resnick; Sean P Colgan; Thomas Patapoff; Randall J Mrsny; C S Awtrey; C Delp-Archer; Peter Weller; James L Madara
Activated eosinophils evoke chloride secretion in model intestinal epithelia primarily via regulated release of 5'-AMP.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(10):5716-23.
1993: Beth A McCormick; Sean P Colgan; C Delp-Archer; S I Miller; James L Madara
Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils.
The Journal of cell biology 1993;123(4):895-907.
1993: Jeffrey B Matthews; C S Awtrey; Gail Hecht; K J Tally; R S Thompson; James L Madara
Phorbol ester sequentially downregulates cAMP-regulated basolateral and apical Cl- transport pathways in T84 cells.
The American journal of physiology 1993;265(4 Pt 1):C1109-17.
1993: Jeffrey B Matthews; C S Awtrey; R Thompson; T Hung; K J Tally; James L Madara
Na(+)-K(+)-2Cl- cotransport and Cl- secretion evoked by heat-stable enterotoxin is microfilament dependent in T84 cells.
The American journal of physiology 1993;265(2 Pt 1):G370-8.
1993: Sean P Colgan; Charles N Serhan; Charles A Parkos; C Delp-Archer; James L Madara
Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers.
The Journal of clinical investigation 1993;92(1):75-82.
1993: James L Madara; S Carlson; James M Anderson
ZO-1 maintains its spatial distribution but dissociates from junctional fibrils during tight junction regulation.
The American journal of physiology 1993;264(5 Pt 1):C1096-101.
1993: James L Madara; Thomas Patapoff; B Gillece-Castro; Sean P Colgan; Charles A Parkos; C Delp; Randall J Mrsny
5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers.
The Journal of clinical investigation 1993;91(5):2320-5.
1993: P Kaoutzani; Charles A Parkos; C Delp-Archer; James L Madara
Isolation of plasma membrane fractions from the intestinal epithelial model T84.
The American journal of physiology 1993;264(5 Pt 1):C1327-35.
1993: K L Cepek; Christina M Parker; James L Madara; Michael B Brenner
Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(8 Pt 1):3459-70.
1993: Sean P Colgan; Charles A Parkos; C Delp; M A Arnaout; James L Madara
Neutrophil migration across cultured intestinal epithelial monolayers is modulated by epithelial exposure to IFN-gamma in a highly polarized fashion.
The Journal of cell biology 1993;120(3):785-98.
1992: Jeffrey B Matthews; C S Awtrey; James L Madara
Microfilament-dependent activation of Na+/K+/2Cl- cotransport by cAMP in intestinal epithelial monolayers.
The Journal of clinical investigation 1992;90(4):1608-13.
1992: Sean P Colgan; Jeffrey B Matthews; Charles A Parkos; C Delp; C S Awtrey; James L Madara
The myeloid leukemia cell line HL-60 produces a factor that induces chloride secretion in cultured epithelial cells.
Journal of leukocyte biology 1992;52(2):183-7.
1992: James L Madara; Charles A Parkos; Sean P Colgan; R J MacLeod; S Nash; J Matthews; C Delp; Wayne I Lencer
Cl- secretion in a model intestinal epithelium induced by a neutrophil-derived secretagogue.
The Journal of clinical investigation 1992;89(6):1938-44.
1992: Wayne I Lencer; C Delp; Marian R Neutra; James L Madara
Mechanism of cholera toxin action on a polarized human intestinal epithelial cell line: role of vesicular traffic.
The Journal of cell biology 1992;117(6):1197-1209.
1992: Charles A Parkos; Sean P Colgan; C Delp; M A Arnaout; James L Madara
Neutrophil migration across a cultured epithelial monolayer elicits a biphasic resistance response representing sequential effects on transcellular and paracellular pathways.
The Journal of cell biology 1992;117(4):757-64.
1992: Asma Nusrat; C Delp; James L Madara
Intestinal epithelial restitution. Characterization of a cell culture model and mapping of cytoskeletal elements in migrating cells.
The Journal of clinical investigation 1992;89(5):1501-11.
1992: Gail Hecht; Athanasia Koutsouris; C Pothoulakis; J T LaMont; James L Madara
Clostridium difficile toxin B disrupts the barrier function of T84 monolayers.
Gastroenterology 1992;102(2):416-23.
1992: R Moore; J Madri; S Carlson; James L Madara
Collagens facilitate epithelial migration in restitution of native guinea pig intestinal epithelium.
Gastroenterology 1992;102(1):119-30.
1992: James L Madara; Charles A Parkos; Sean P Colgan; Asma Nusrat; K Atisook; P Kaoutzani
The movement of solutes and cells across tight junctions.
Annals of the New York Academy of Sciences 1992;664():47-60.
1991: Charles A Parkos; C Delp; M A Arnaout; James L Madara
Neutrophil migration across a cultured intestinal epithelium. Dependence on a CD11b/CD18-mediated event and enhanced efficiency in physiological direction.
The Journal of clinical investigation 1991;88(5):1605-12.
1991: M Shapiro; J Matthews; Gail Hecht; C Delp; James L Madara
Stabilization of F-actin prevents cAMP-elicited Cl- secretion in T84 cells.
The Journal of clinical investigation 1991;87(6):1903-9.
1991: S Nash; Charles A Parkos; Asma Nusrat; C Delp; James L Madara
In vitro model of intestinal crypt abscess. A novel neutrophil-derived secretagogue activity.
The Journal of clinical investigation 1991;87(4):1474-7.
1991: K Atisook; James L Madara
An oligopeptide permeates intestinal tight junctions at glucose-elicited dilatations. Implications for oligopeptide absorption.
Gastroenterology 1991;100(3):719-24.
1991: James L Madara; S Carlson
Supraphysiologic L-tryptophan elicits cytoskeletal and macromolecular permeability alterations in hamster small intestinal epithelium in vitro.
The Journal of clinical investigation 1991;87(2):454-62.
1991: James L Madara; S Nash; Charles A Parkos
Neutrophil-epithelial cell interactions in the intestine.
Advances in experimental medicine and biology 1991;314():329-34.
1990: James L Madara
Warner-Lambert/Parke-Davis Award lecture. Pathobiology of the intestinal epithelial barrier.
The American journal of pathology 1990;137(6):1273-81.
1990: R Moore; C Pothoulakis; J T LaMont; S Carlson; James L Madara
C. difficile toxin A increases intestinal permeability and induces Cl- secretion.
The American journal of physiology 1990;259(2 Pt 1):G165-72.
1990: James L Madara
Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: physiological rearrangement of tight junctions.
The Journal of membrane biology 1990;116(2):177-84.
1990: K Atisook; S Carlson; James L Madara
Effects of phlorizin and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia.
The American journal of physiology 1990;258(1 Pt 1):C77-85.
1989: R Moore; S Carlson; James L Madara
Villus contraction aids repair of intestinal epithelium after injury.
The American journal of physiology 1989;257(2 Pt 1):G274-83.
1989: James L Madara
Epithelial cells develop membrane wounds--and recover!
Gastroenterology 1989;96(5 Pt 1):1360-1.
1989: James L Madara
Loosening tight junctions. Lessons from the intestine.
The Journal of clinical investigation 1989;83(4):1089-94.
1989: R Moore; S Carlson; James L Madara
Rapid barrier restitution in an in vitro model of intestinal epithelial injury.
Laboratory investigation; a journal of technical methods and pathology 1989;60(2):237-44.
1988: Gail Hecht; C Pothoulakis; J T LaMont; James L Madara
Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers.
The Journal of clinical investigation 1988;82(5):1516-24.
1988: S Nash; J Stafford; James L Madara
The selective and superoxide-independent disruption of intestinal epithelial tight junctions during leukocyte transmigration.
Laboratory investigation; a journal of technical methods and pathology 1988;59(4):531-7.
1988: James L Madara
Tight junction dynamics: is paracellular transport regulated?
Cell 1988;53(4):497-8.
1988: James L Madara; J Stafford; D Barenberg; S Carlson
Functional coupling of tight junctions and microfilaments in T84 monolayers.
The American journal of physiology 1988;254(3 Pt 1):G416-23.
1987: James L Madara; R Moore; S Carlson
Alteration of intestinal tight junction structure and permeability by cytoskeletal contraction.
The American journal of physiology 1987;253(6 Pt 1):C854-61.
1987: S Nash; J Stafford; James L Madara
Effects of polymorphonuclear leukocyte transmigration on the barrier function of cultured intestinal epithelial monolayers.
The Journal of clinical investigation 1987;80(4):1104-13.
1987: J S Trier; C H Allan; M A Marcial; James L Madara
Structural features of the apical and tubulovesicular membranes of rodent small intestinal tuft cells.
The Anatomical record 1987;219(1):69-77.
1987: James L Madara; J R Pappenheimer
Structural basis for physiological regulation of paracellular pathways in intestinal epithelia.
The Journal of membrane biology 1987;100(2):149-64.