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Paolo Madeddu

Research Profile

Disorders

Physiology

Neovascularization, Physiologic

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Chemicals & Drugs

Anatomy

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TOP 3
Gaia Spinetti; Stefano Riboldi; Francesco Rosa; Elena Sangalli; Fausto Sessa; Elisa Avolio; Antonio P Beltrami; Franco Carnelli; Daniela Cordella; Costanza Emanueli; Orazio Fortunato; Ambra Gotti; Sergio Losa; Paolo Madeddu
Global remodeling of the vascular stem cell niche in bone marrow of diabetic patients: implication of the microRNA-155/FOXO3a signaling pathway.
Betty Descamps; Paolo Madeddu; Costanza Emanueli
S100A1: A novel and essential molecular component for postischemic angiogenesis.
Rajesh G Katare; Pujika Emani Munasinghe; Deepti Muthukrishnan; Atsuhiko Oikawa; Gianni Angelini; Elisa Avolio; Antonio P Beltrami; Daniela Cesselli; Costanza Emanueli; Paolo Madeddu
Boosting the pentose phosphate pathway restores cardiac progenitor cell availability in diabetes.

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All Publications

2013: Gaia Spinetti; Stefano Riboldi; Francesco Rosa; Elena Sangalli; Fausto Sessa; Elisa Avolio; Antonio P Beltrami; Franco Carnelli; Daniela Cordella; Costanza Emanueli; Orazio Fortunato; Ambra Gotti; Sergio Losa; Paolo Madeddu
Global remodeling of the vascular stem cell niche in bone marrow of diabetic patients: implication of the microRNA-155/FOXO3a signaling pathway.
Circulation research 2013;112(3):510-22.
2013: Betty Descamps; Paolo Madeddu; Costanza Emanueli
S100A1: A novel and essential molecular component for postischemic angiogenesis.
Circulation research 2013;112(1):3-5.
2013: Rajesh G Katare; Pujika Emani Munasinghe; Deepti Muthukrishnan; Atsuhiko Oikawa; Gianni Angelini; Elisa Avolio; Antonio P Beltrami; Daniela Cesselli; Costanza Emanueli; Paolo Madeddu
Boosting the pentose phosphate pathway restores cardiac progenitor cell availability in diabetes.
Cardiovascular research 2013;97(1):55-65.
2012: Andrea Caporali; Alessandro Cardinali; Ezio Faglia; Orazio Fortunato; Ambra Gotti; Manuela Hofner; Sergio Losa; Paolo Madeddu; Marco Meloni; Ashley M Miller; Tijana Mitic; Audrey Nailor; Christa Noehammer; Gaia Spinetti; Klemens Vierlinger; Costanza Emanueli
Soluble ST2 is regulated by p75 neurotrophin receptor and predicts mortality in diabetic patients with critical limb ischemia.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(12):e149-60.
2012: Giuseppe Mangialardi; Atsuhiko Oikawa; Carlotta Reni; Paolo Madeddu
Bone marrow microenvironment: a newly recognized target for diabetes-induced cellular damage.
Endocrine, metabolic & immune disorders drug targets 2012;12(2):159-67.
2012: Silvia Amadesi; Raimondo Ascione; Elisa Avolio; Antonio P Beltrami; Elisa Cangiano; Daniela Cesselli; Costanza Emanueli; Orazio Fortunato; Stephen P Hunt; Rajesh G Katare; Marco Meloni; Atsuhiko Oikawa; Carlotta Reni; Gaia Spinetti; Marco Valgimigli; Paolo Madeddu
Role for substance p-based nociceptive signaling in progenitor cell activation and angiogenesis during ischemia in mice and in human subjects.
Circulation 2012;125(14):1774-86, S1-19.
2012: Ayman Al Haj Zen; Paolo Madeddu
DLK1: a novel negative regulator of angiogenesis?
Cardiovascular research 2012;93(2):213-4.
2012: Yu-Xin Cui; Tom Johnson; Gianni D Angelini; Andreas Baumbach; Debbie Marsden; Barnaby C Reeves; Chris A Rogers; Paolo Madeddu
Stepwise optimization of the procedure for assessment of circulating progenitor cells in patients with myocardial infarction.
PloS one 2012;7(1):e30389.
2011: Rajesh G Katare; Kathryn Mitchell; Federica Riu; Gianni Angelini; Elisa Avolio; Antonio P Beltrami; Paola Campagnolo; Daniela Cesselli; Yuxin Cui; Costanza Emanueli; Orazio Fortunato; Miriam Gubernator; Paolo Madeddu
Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132.
Circulation research 2011;109(8):894-906.
2011: Rajesh Katare; Andrea Caporali; Lorena Zentilin; Elisa Avolio; Graciela Sala-Newby; Atsuhiko Oikawa; Daniela Cesselli; Antonio Paolo Beltrami; Mauro Giacca; Costanza Emanueli; Paolo Madeddu
Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling.
Circulation research 2011;108(10):1238-51.
2011: Gaia Spinetti; Orazio Fortunato; Daniela Cordella; Paola Portararo; Nicolle Kraenkel; Rajesh G Katare; Graciela B Sala-Newby; Christine Richer; Marie-Pascale Vincent; François Alhenc-Gelas; Giancarlo Tonolo; Sara Cherchi; Costanza Emanueli; Paolo Madeddu
Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells.
Circulation research 2011;108(3):284-93.
2011: Gaia Spinetti; Orazio Fortunato; Nicolle Kraenkel; Paolo Madeddu
Close encounters of the third kind: progenitor cells land on the platelet-enriched vascular surface.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(2):243-4.
2011: Andrea Caporali; Marco Meloni; Christine Völlenkle; Desiree Bonci; Graciela B Sala-Newby; Roberta Addis; Gaia Spinetti; Sergio Losa; Rachel Masson; Andrew H Baker; Reuven Agami; Carlos le Sage; Gianluigi Condorelli; Paolo Madeddu; Fabio Martelli; Costanza Emanueli
Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia.
Circulation 2011;123(3):282-91.
2011: Nicolle Kraenkel; Gaia Spinetti; Silvia Amadesi; Paolo Madeddu
Targeting stem cell niches and trafficking for cardiovascular therapy.
Pharmacology & therapeutics 2011;129(1):62-81.
2011: Paolo Madeddu
Stem cell therapy for cardiovascular regeneration: the beginning or the end of all hearts' hopes.
Pharmacology & therapeutics 2011;129(1):1-2.
2010: P Dominek; P Campagnolo; M H-Zadeh; Nicolle Kraenkel; M Chilosi; J A Sharman; Andrea Caporali; G Mangialardi; Gaia Spinetti; Costanza Emanueli; M Pignatelli; Paolo Madeddu
Role of human tissue kallikrein in gastrointestinal stromal tumour invasion.
British journal of cancer 2010;103(9):1422-31.
2010: Rajesh Katare; Andrea Caporali; Costanza Emanueli; Paolo Madeddu
Benfotiamine improves functional recovery of the infarcted heart via activation of pro-survival G6PD/Akt signaling pathway and modulation of neurohormonal response.
Journal of molecular and cellular cardiology 2010;49(4):625-38.
2010: Ayman Al Haj Zen; Atsuhiko Oikawa; Miriam Bazan-Peregrino; Marco Meloni; Costanza Emanueli; Paolo Madeddu
Inhibition of delta-like-4-mediated signaling impairs reparative angiogenesis after ischemia.
Circulation research 2010;107(2):283-93.
2010: Rocco De Siena; Luigi Balducci; Antonella Blasi; Manuela Gessica Montanaro; Marilisa Saldarelli; Vittorio Saponaro; Carmela Martino; Gaetano Logrieco; Antonio Soleti; Simona Fiobellot; Paolo Madeddu; Giacomo Rossi; Dragana Vukasovic; Antonio Crovace; Silvia Cristini; Gloria Invernici; Eugenio Parati; Giulio Alessandri
Omentum-derived stromal cells improve myocardial regeneration in pig post-infarcted heart through a potent paracrine mechanism.
Experimental cell research 2010;316(11):1804-15.
2010: Brunella Cristofaro; Oliver A Stone; Andrea Caporali; David Dawbarn; Nicholas Ieronimakis; Morayma Reyes; Paolo Madeddu; David O Bates; Costanza Emanueli
Neurotrophin-3 is a novel angiogenic factor capable of therapeutic neovascularization in a mouse model of limb ischemia.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(6):1143-50.
2010: Paola Campagnolo; Daniela Cesselli; Ayman Al Haj Zen; Antonio Paolo Beltrami; Nicolle Kraenkel; Rajesh G Katare; Gianni Angelini; Costanza Emanueli; Paolo Madeddu
Human adult vena saphena contains perivascular progenitor cells endowed with clonogenic and proangiogenic potential.
Circulation 2010;121(15):1735-45.
2010: Marco Meloni; Andrea Caporali; Gallia Graiani; Costanza Lagrasta; Rajesh Katare; Sophie Van Linthout; Frank Spillmann; Ilaria Campesi; Paolo Madeddu; Federico Quaini; Costanza Emanueli
Nerve growth factor promotes cardiac repair following myocardial infarction.
Circulation research 2010;106(7):1275-84.
2010: Mauro Siragusa; Rajesh G Katare; Marco Meloni; Federico Damilano; Emilio Hirsch; Costanza Emanueli; Paolo Madeddu
Involvement of phosphoinositide 3-kinase gamma in angiogenesis and healing of experimental myocardial infarction in mice.
Circulation research 2010;106(4):757-68.
2010: Rajesh G Katare; Andrea Caporali; Atsuhiko Oikawa; Marco Meloni; Costanza Emanueli; Paolo Madeddu
Vitamin B1 analog benfotiamine prevents diabetes-induced diastolic dysfunction and heart failure through Akt/Pim-1-mediated survival pathway.
Circulation. Heart failure 2010;3(2):294-305.
2010: Atsuhiko Oikawa; Mauro Siragusa; Federico Quaini; Giuseppe Mangialardi; Rajesh G Katare; Andrea Caporali; Jaap D van Buul; Floris P J van Alphen; Gallia Graiani; Gaia Spinetti; Nicolle Kraenkel; Lucia Prezioso; Costanza Emanueli; Paolo Madeddu
Diabetes mellitus induces bone marrow microangiopathy.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(3):498-508.
2010: Nicolle Kraenkel; Stephen Paul Armstrong; Craig Alexander McArdle; Colin M Dayan; Paolo Madeddu
Distinct kinin-induced functions are altered in circulating cells of young type 1 diabetic patients.
PloS one 2010;5(6):e11146.
2009: Ayman Al Haj Zen; Paolo Madeddu
Notch signalling in ischaemia-induced angiogenesis.
Biochemical Society transactions 2009;37(Pt 6):1221-7.
2009: Lucíola S Barcelos; Cécile Duplaa; Nicolle Kraenkel; Gallia Graiani; Gloria Invernici; Rajesh Katare; Mauro Siragusa; Marco Meloni; Ilaria Campesi; Manuela Monica; Andreas Simm; Paola Campagnolo; Giuseppe Mangialardi; lara Stevanato; Giulio Alessandri; Costanza Emanueli; Paolo Madeddu
Human CD133+ progenitor cells promote the healing of diabetic ischemic ulcers by paracrine stimulation of angiogenesis and activation of Wnt signaling.
Circulation research 2009;104(9):1095-102.
2009: Oliver A Stone; Christine Richer; Costanza Emanueli; Vincent van Weel; Paul H A Quax; Rajesh Katare; Nicolle Kraenkel; Paola Campagnolo; Luciola S Barcelos; Mauro Siragusa; Graciela B Sala-Newby; Danila Baldessari; Marina Mione; Marie P Vincent; Andrew V Benest; Ayman Al Haj Zen; Julien Gonzalez; David O Bates; François Alhenc-Gelas; Paolo Madeddu
Critical role of tissue kallikrein in vessel formation and maturation: implications for therapeutic revascularization.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(5):657-64.
2009: Nicolle Kraenkel; Paolo Madeddu
Helping the circulatory system heal itself: manipulating kinin signaling to promote neovascularization.
Expert review of cardiovascular therapy 2009;7(3):215-9.
2008: Nicolle Kraenkel; Rajesh G Katare; Mauro Siragusa; Luciola S Barcelos; Paola Campagnolo; Giuseppe Mangialardi; Orazio Fortunato; Gaia Spinetti; Nguyen Tran; Kai Zacharowski; Wojciech Wojakowski; Iwona Mroz; Andrew Herman; Jocelyn E Manning Fox; Patrick E MacDonald; Joost P Schanstra; Jean-Loup Bascands; Raimondo Ascione; Gianni Angelini; Costanza Emanueli; Paolo Madeddu
Role of kinin B2 receptor signaling in the recruitment of circulating progenitor cells with neovascularization potential.
Circulation research 2008;103(11):1335-43.
2008: Gloria Invernici; Paolo Madeddu; Costanza Emanueli; Eugenio Parati; Giulio Alessandri
Human fetal aorta-derived vascular progenitor cells: identification and potential application in ischemic diseases.
Cytotechnology 2008;58(1):43-7.
2008: Andrea Caporali; Elisabetta Pani; Anton J G Horrevoets; Nicolle Kraenkel; Atsuhiko Oikawa; Graciela B Sala-Newby; Marco Meloni; Brunella Cristofaro; Gallia Graiani; Aurelie S Leroyer; Chantal M Boulanger; Gaia Spinetti; Sung Ok Yoon; Paolo Madeddu; Costanza Emanueli
Neurotrophin p75 receptor (p75NTR) promotes endothelial cell apoptosis and inhibits angiogenesis: implications for diabetes-induced impaired neovascularization in ischemic limb muscles.
Circulation research 2008;103(2):e15-26.
2008: Gaia Spinetti; Nicolle Kraenkel; Costanza Emanueli; Paolo Madeddu
Diabetes and vessel wall remodelling: from mechanistic insights to regenerative therapies.
Cardiovascular research 2008;78(2):265-73.
2008: Andrea Caporali; Graciela B Sala-Newby; M Meloni; Gallia Graiani; E Pani; B Cristofaro; Andrew C Newby; Paolo Madeddu; Costanza Emanueli
Identification of the prosurvival activity of nerve growth factor on cardiac myocytes.
Cell death and differentiation 2008;15(2):299-311.
2008: Gloria Invernici; Silvia Cristini; Paolo Madeddu; Stefano Brock; Frank Spillmann; Pia Bernasconi; Cristina Cappelletti; Chiara Calatozzolo; Umberto Fascio; Gianluigi Bisleri; Claudio Muneretto; Giulio Alessandri; Eugenio Parati
Human adult skeletal muscle stem cells differentiate into cardiomyocyte phenotype in vitro.
Experimental cell research 2008;314(2):366-76.
2008: Paolo Madeddu; Nicolle Kraenkel; Luciola S Barcelos; Mauro Siragusa; Paola Campagnolo; Atsuhiko Oikawa; Andrea Caporali; Andrew Herman; Ornella Azzolino; Laura Barberis; Alessia Perino; Federico Damilano; Costanza Emanueli; Emilio Hirsch
Phosphoinositide 3-kinase gamma gene knockout impairs postischemic neovascularization and endothelial progenitor cell functions.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(1):68-76.
2007: Gloria Invernici; Costanza Emanueli; Paolo Madeddu; Silvia Cristini; Sergio Gadau; Anna Benetti; Emilio Ciusani; Giorgio Stassi; Mauro Siragusa; Roberto F Nicosia; Cesare Peschle; Umberto Fascio; Augusto Colombo; Tommaso Rizzuti; Eugenio Parati; Giulio Alessandri
Human fetal aorta contains vascular progenitor cells capable of inducing vasculogenesis, angiogenesis, and myogenesis in vitro and in a murine model of peripheral ischemia.
The American journal of pathology 2007;170(6):1879-92.
2007: Paolo Madeddu; Costanza Emanueli; Samir S El-Dahr
Mechanisms of disease: the tissue kallikrein-kinin system in hypertension and vascular remodeling.
Nature clinical practice. Nephrology 2007;3(4):208-21.
2007: Costanza Emanueli; Angela Monopoli; Nicolle Kraenkel; M Meloni; Sergio Gadau; Ilaria Campesi; Ennio Ongini; Paolo Madeddu
Nitropravastatin stimulates reparative neovascularisation and improves recovery from limb Ischaemia in type-1 diabetic mice.
British journal of pharmacology 2007;150(7):873-82.
2007: Costanza Emanueli; Andrea Caporali; Nicolle Kraenkel; Brunella Cristofaro; Sophie Van Linthout; Paolo Madeddu
Type-2 diabetic Lepr(db/db) mice show a defective microvascular phenotype under basal conditions and an impaired response to angiogenesis gene therapy in the setting of limb ischemia.
Frontiers in bioscience : a journal and virtual library 2007;12():2003-12.
2006: Paolo Madeddu; Costanza Emanueli; Frank Spillmann; M Meloni; Nadine Bouby; Christine Richer; François Alhenc-Gelas; Vincent van Weel; Daniel Eefting; Paul H A Quax; Y Hu; Q Xu; A L Hemdahl; Jolanda van Golde; M Huijberts; Q de Lussanet; H Struijker Boudier; thierry couffinhal; C Duplaa; S Chimenti; Lidia Staszewsky; R Latini; V Baumans; B I Levy
Murine models of myocardial and limb ischemia: diagnostic end-points and relevance to clinical problems.
Vascular pharmacology 2006;45(5):281-301.
2006: Costanza Emanueli; Paolo Madeddu
Therapeutic angiogenesis: translating experimental concepts to medically relevant goals.
Vascular pharmacology 2006;45(5):334-9.
2006: Frank Spillmann; Gallia Graiani; Sophie Van Linthout; Marco Meloni; Ilaria Campesi; Costanza Lagrasta; Dirk Westermann; Carsten Tschöpe; Federico Quaini; Costanza Emanueli; Paolo Madeddu
Regional and global protective effects of tissue kallikrein gene delivery to the peri-infarct myocardium.
Regenerative medicine 2006;1(2):235-54.
2006: Sergio Gadau; Costanza Emanueli; Sophie Van Linthout; Gallia Graiani; M Todaro; M Meloni; Ilaria Campesi; Gloria Invernici; Frank Spillmann; K Ward; Paolo Madeddu
Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis.
Diabetologia 2006;49(2):405-20.
2005: Costanza Emanueli; Majlinda Lako; Miodrag Stojkovic; Paolo Madeddu
In search of the best candidate for regeneration of ischemic tissues: are embryonic/fetal stem cells more advantageous than adult counterparts?
Thrombosis and haemostasis 2005;94(4):738-49.
2005: Gallia Graiani; Costanza Lagrasta; Enrica Migliaccio; Frank Spillmann; Marco Meloni; Paolo Madeddu; Federico Quaini; Ines Martin Padura; Luisa Lanfrancone; Pier Giuseppe Pelicci; Costanza Emanueli
Genetic deletion of the p66Shc adaptor protein protects from angiotensin II-induced myocardial damage.
Hypertension 2005;46(2):433-40.
2005: Paolo Madeddu
Therapeutic angiogenesis and vasculogenesis for tissue regeneration.
Experimental physiology 2005;90(3):315-26.
2005: Angela Del Rosso; Oliver Distler; Anna Franca Milia; Costanza Emanueli; Lidia Ibba-Manneschi; Serena Guiducci; Maria Letizia Conforti; Sergio Generini; Alberto Pignone; Steffen Gay; Paolo Madeddu; Marco Matucci-Cerinic
Increased circulating levels of tissue kallikrein in systemic sclerosis correlate with microvascular involvement.
Annals of the rheumatic diseases 2005;64(3):382-7.
2005: Sophie Van Linthout; Paolo Madeddu
Ex vivo gene transfer for improvement of transplanted pancreatic islet viability and function.
Current pharmaceutical design 2005;11(22):2927-40.
2004: Paolo Madeddu; Costanza Emanueli; Elvira Pelosi; Maria Bonaria Salis; Anna Maria Cerio; Giuseppina Bonanno; Mariella Patti; Giorgio Stassi; Gianluigi Condorelli; Cesare Peschle
Transplantation of low dose CD34+KDR+ cells promotes vascular and muscular regeneration in ischemic limbs.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(14):1737-9.
2004: Costanza Emanueli; Sophie Van Linthout; Maria Bonaria Salis; Angela Monopoli; Piero Del Soldato; Ennio Ongini; Paolo Madeddu
Nitric oxide-releasing aspirin derivative, NCX 4016, promotes reparative angiogenesis and prevents apoptosis and oxidative stress in a mouse model of peripheral ischemia.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(11):2082-7.
2004: Costanza Emanueli; Maria Bonaria Salis; Sophie Van Linthout; Marco Meloni; Elisa Desortes; Jean-Sébastien Silvestre; Michel Clergue; Carlos D Figueroa; Sergio Gadau; Gianluigi Condorelli; Paolo Madeddu
Akt/protein kinase B and endothelial nitric oxide synthase mediate muscular neovascularization induced by tissue kallikrein gene transfer.
Circulation 2004;110(12):1638-44.
2004: Maria Bonaria Salis; Gallia Graiani; Elisa Desortes; Ruth B Caldwell; Paolo Madeddu; Costanza Emanueli
Nerve growth factor supplementation reverses the impairment, induced by Type 1 diabetes, of hindlimb post-ischaemic recovery in mice.
Diabetologia 2004;47(6):1055-63.
2004: Gallia Graiani; Costanza Emanueli; Elisa Desortes; Sophie Van Linthout; Alessandra Pinna; C D Figueroa; Luigi Manni; Paolo Madeddu
Nerve growth factor promotes reparative angiogenesis and inhibits endothelial apoptosis in cutaneous wounds of Type 1 diabetic mice.
Diabetologia 2004;47(6):1047-54.
2004: Paolo Porcu; Costanza Emanueli; Elisa Desortes; Giovanni M Marongiu; Franco Piredda; Lee Chao; Julie Chao; Paolo Madeddu
Circulating tissue kallikrein levels correlate with severity of carotid atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(6):1104-10.
2004: Giulio Alessandri; Costanza Emanueli; Paolo Madeddu
Genetically engineered stem cell therapy for tissue regeneration.
Annals of the New York Academy of Sciences 2004;1015():271-84.
2004: Costanza Emanueli; Gallia Graiani; Maria Bonaria Salis; Sergio Gadau; Elisa Desortes; Paolo Madeddu
Prophylactic gene therapy with human tissue kallikrein ameliorates limb ischemia recovery in type 1 diabetic mice.
Diabetes 2004;53(4):1096-103.
2003: Costanza Emanueli; Peter Schratzberger; Rudolf Kirchmair; Paolo Madeddu
Paracrine control of vascularization and neurogenesis by neurotrophins.
British journal of pharmacology 2003;140(4):614-9.
2003: Roberta Maestri; Anna Franca Milia; Maria Bonaria Salis; Gallia Graiani; Costanza Lagrasta; Manuela Monica; Domenico Corradi; Costanza Emanueli; Paolo Madeddu
Cardiac hypertrophy and microvascular deficit in kinin B2 receptor knockout mice.
Hypertension 2003;41(5):1151-5.
2003: Costanza Emanuelia; Paolo Madeddu
Human tissue kallikrein: a new bullet for the treatment of ischemia.
Current pharmaceutical design 2003;9(7):589-97.
2002: Costanza Emanueli; Maria Bonaria Salis; Alessandra Pinna; Gallia Graiani; Luigi Manni; Paolo Madeddu
Nerve growth factor promotes angiogenesis and arteriogenesis in ischemic hindlimbs.
Circulation 2002;106(17):2257-62.
2002: Anna Franca Milia; Maria Bonaria Salis; Tiziana Stacca; Alessandra Pinna; Paolo Madeddu; Marcello Trevisani; Pierangelo Geppetti; Costanza Emanueli
Protease-activated receptor-2 stimulates angiogenesis and accelerates hemodynamic recovery in a mouse model of hindlimb ischemia.
Circulation research 2002;91(4):346-52.
2002: Costanza Emanueli; Maria Bonaria Salis; Alessandra Pinna; Tiziana Stacca; Anna Franca Milia; Alessandra Spano; Julie Chao; Lee Chao; Luigi Sciola; Paolo Madeddu
Prevention of diabetes-induced microangiopathy by human tissue kallikrein gene transfer.
Circulation 2002;106(8):993-9.
2002: Anna Rizzi; Maria Bonaria Salis; Roberto Ciccocioppo; Giuliano Marzola; Raffaella Bigoni; Remo Guerrini; Maurizio Massi; Paolo Madeddu; Severo Salvadori; Domenico Regoli; Girolamo Calo'
Pharmacological characterisation of [(pX)Phe4]nociceptin(1-13)NH2 analogues. 2. In vivo studies.
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(6):450-6.
2002: Costanza Emanueli; Maria Bonaria Salis; Tiziana Stacca; Alessandra Pinna; Leonardo Gaspa; Alessandra Spano; Paolo Madeddu
Ramipril improves hemodynamic recovery but not microvascular response to ischemia in spontaneously hypertensive rats.
American journal of hypertension 2002;15(5):410-5.
2002: Costanza Emanueli; Maria Bonaria Salis; Tiziana Stacca; Gianfranco Pintus; Rudolf Kirchmair; Jeffrey M Isner; Alessandra Pinna; Leonardo Gaspa; Domenico Regoli; Cécile Cayla; João B Pesquero; Michael Bader; Paolo Madeddu
Targeting kinin B(1) receptor for therapeutic neovascularization.
Circulation 2002;105(3):360-6.
2002: Costanza Emanueli; Maria Bonaria Salis; Tiziana Stacca; Alessandra Pinna; Leonardo Gaspa; Paolo Madeddu; Paolo Maddeddu
Angiotensin AT(1) receptor signalling modulates reparative angiogenesis induced by limb ischaemia.
British journal of pharmacology 2002;135(1):87-92.
2002: Paolo Porcu; Costanza Emanueli; Maria Kapatsoris; Julie Chao; Lee Chao; Paolo Madeddu
Reversal of angiogenic growth factor upregulation by revascularization of lower limb ischemia.
Circulation 2002;105(1):67-72.
2001: Costanza Emanueli; Paolo Madeddu
Targeting kinin receptors for the treatment of tissue ischaemia.
Trends in pharmacological sciences 2001;22(9):478-84.
2001: Costanza Emanueli; Paolo Madeddu
Angiogenesis gene therapy to rescue ischaemic tissues: achievements and future directions.
British journal of pharmacology 2001;133(7):951-8.
2001: Costanza Emanueli; Maria Bonaria Salis; Tiziana Stacca; Leonardo Gaspa; Julie Chao; Lee Chao; A Piana; Paolo Madeddu
Rescue of impaired angiogenesis in spontaneously hypertensive rats by intramuscular human tissue kallikrein gene transfer.
Hypertension 2001;38(1):136-41.
2001: Paolo Madeddu; Costanza Emanueli; Maria Bonaria Salis; A Franca Milia; Tiziana Stacca; L Carta; Alessandra Pinna; M Deiana; Leonardo Gaspa
Role of calcitonin gene-related peptide and kinins in post-ischemic intestinal reperfusion.
Peptides 2001;22(6):915-22.
2001: Paolo Madeddu; C P Vio; Stefania Straino; Maria Bonaria Salis; Anna Franca Milia; Costanza Emanueli
Renal phenotype of low kallikrein rats.
Kidney international 2001;59(6):2233-42.
2001: Costanza Emanueli; A Minasi; Antonella Zacheo; Julie Chao; Lee Chao; Maria Bonaria Salis; Stefania Straino; Maria Grazia Tozzi; R Smith; Leonardo Gaspa; G Bianchini; F Stillo; Maurizio C Capogrossi; Paolo Madeddu
Local delivery of human tissue kallikrein gene accelerates spontaneous angiogenesis in mouse model of hindlimb ischemia.
Circulation 2001;103(1):125-32.
2000: Costanza Emanueli; Antonella Zacheo; A Minasi; Julie Chao; Lee Chao; Maria Bonaria Salis; Tiziana Stacca; Stefania Straino; Maurizio C Capogrossi; Paolo Madeddu
Adenovirus-mediated human tissue kallikrein gene delivery induces angiogenesis in normoperfused skeletal muscle.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(11):2379-85.
2000: Maria Bonaria Salis; Costanza Emanueli; Anna Franca Milia; R Guerrini; Paolo Madeddu
Studies of the cardiovascular effects of nociceptin and related peptides.
Peptides 2000;21(7):985-93.
2000: Costanza Emanueli; Maria Bonaria Salis; C Figueroa; Julie Chao; Lee Chao; Leonardo Gaspa; Maurizio C Capogrossi; Paolo Madeddu
Participation of kinins in the captopril-induced inhibition of intimal hyperplasia caused by interruption of carotid blood flow in the mouse.
British journal of pharmacology 2000;130(5):1076-82.
2000: Costanza Emanueli; Maria Bonaria Salis; Julie Chao; Lee Chao; Jun Agata; Kuei-Fu Lin; A Munaò; Stefania Straino; A Minasi; Maurizio C Capogrossi; Paolo Madeddu
Adenovirus-mediated human tissue kallikrein gene delivery inhibits neointima formation induced by interruption of blood flow in mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(6):1459-66.
2000: Paolo Madeddu; Costanza Emanueli; Roberta Maestri; Maria Bonaria Salis; A Minasi; Maurizio C Capogrossi; Giorgio Olivetti
Angiotensin II type 1 receptor blockade prevents cardiac remodeling in bradykinin B(2) receptor knockout mice.
Hypertension 2000;35(1 Pt 2):391-6.
1999: Costanza Emanueli; Roberta Maestri; Domenico Corradi; R Marchione; A Minasi; Maria Grazia Tozzi; Maria Bonaria Salis; Stefania Straino; Maurizio C Capogrossi; Giorgio Olivetti; Paolo Madeddu
Dilated and failing cardiomyopathy in bradykinin B(2) receptor knockout mice.
Circulation 1999;100(23):2359-65.
1999: Paolo Madeddu; Maria Bonaria Salis; Costanza Emanueli
Altered baroreflex control of heart rate in bradykinin B2-receptor knockout mice.
Immunopharmacology 1999;45(1-3):21-7.
1999: Paolo Madeddu; Costanza Emanueli; Leonardo Gaspa; B Salis; Anna Franca Milia; Lee Chao; Julie Chao
Role of the bradykinin B2 receptor in the maturation of blood pressure phenotype: lesson from transgenic and knockout mice.
Immunopharmacology 1999;44(1-2):9-13.
1999: Costanza Emanueli; Paolo Madeddu
Role of the kallikrein-kinin system in the maturation of cardiovascular phenotype.
American journal of hypertension 1999;12(10 Pt 1):988-99.
1999: Costanza Emanueli; Julie Chao; D Regoli; Lee Chao; A Ni; Paolo Madeddu
The bradykinin B1 receptor and the central regulation of blood pressure in spontaneously hypertensive rats.
British journal of pharmacology 1999;126(8):1769-76.
1999: Paolo Madeddu; Maria Bonaria Salis; Anna Franca Milia; Costanza Emanueli; R Guerrini; Domenico Regoli; G Calò
Cardiovascular effects of nociceptin in unanesthetized mice.
Hypertension 1999;33(3):914-9.
1998: Paolo Madeddu; Anna Franca Milia; Maria Bonaria Salis; Leonardo Gaspa; W Gross; Andrea Lippoldt; Costanza Emanueli
Renovascular hypertension in bradykinin B2-receptor knockout mice.
Hypertension 1998;32(3):503-9.
1998: Costanza Emanueli; Eileen F Grady; Paolo Madeddu; M Figini; Nigel W Bunnett; D Parisi; Domenico Regoli; Pierangelo Geppetti
Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P.
Hypertension 1998;31(6):1299-304.
1998: Costanza Emanueli; E Fink; Anna Franca Milia; Maria Bonaria Salis; M Conti; Maria Piera Demontis; Paolo Madeddu
Enhanced blood pressure sensitivity to deoxycorticosterone in mice with disruption of bradykinin B2 receptor gene.
Hypertension 1998;31(6):1278-83.
1998: Maria Piera Demontis; Maria Vittoria Varoni; A R Volpe; Costanza Emanueli; Paolo Madeddu
Role of nitric oxide synthase inhibition in the acute hypertensive response to intracerebroventricular cadmium.
British journal of pharmacology 1998;123(1):129-35.
1997: Costanza Emanueli; G R Angioni; Vittorio Anania; A Spissu; Paolo Madeddu
Blood pressure responses to acute or chronic captopril in mice with disruption of bradykinin B2-receptor gene.
Journal of hypertension 1997;15(12 Pt 2):1701-6.
1997: Paolo Madeddu; Maria Vittoria Varoni; Domenico Palomba; Costanza Emanueli; Maria Piera Demontis; Nicola Glorioso; Paolo Dessì-Fulgheri; Riccardo Sarzani; Vittorio Anania
Cardiovascular phenotype of a mouse strain with disruption of bradykinin B2-receptor gene.
Circulation 1997;96(10):3570-8.
1997: Paolo Madeddu; Costanza Emanueli; QING SONG; Maria Vittoria Varoni; Maria Piera Demontis; Vittorio Anania; Nicola Glorioso; Julie Chao; N Gorioso
Regulation of bradykinin B2-receptor expression by oestrogen.
British journal of pharmacology 1997;121(8):1763-9.
1997: Costanza Emanueli; Paolo Madeddu
Effect of early blockade of bradykinin B2-receptors on the blood pressure phenotype of normotensive and spontaneously hypertensive rats.
Pharmacological research : the official journal of the Italian Pharmacological Society 1997;35(6):522-6.
1997: Paolo Madeddu; Maria Vittoria Varoni; Maria Piera Demontis; Julie Chao; J A Simson; Nicola Glorioso; Vittorio Anania
Kallikrein-kinin system and blood pressure sensitivity to salt.
Hypertension 1997;29(1 Pt 2):471-7.
1996: Paolo Madeddu; Paolo Pinna Parpaglia; Nicola Glorioso; Lee Chao; Julie Chao
Antisense inhibition of the brain kallikrein-kinin system.
Hypertension 1996;28(6):980-7.
1996: Paolo Madeddu; Maria Vittoria Varoni; Maria Piera Demontis; P Pinna-Parpaglia; Nicola Glorioso; Vittorio Anania
Blood pressure sensitivity to salt in rats with low urinary kallikrein excretion.
Immunopharmacology 1996;33(1-3):301-4.
1996: Paolo Madeddu; Maria Vittoria Varoni; Maria Piera Demontis; P Pinna-Parpaglia; Nicola Glorioso; Vittorio Anania
Urinary kallikrein: a marker of blood pressure sensitivity to salt.
Kidney international 1996;49(5):1422-7.
1996: Paolo Madeddu; P Pinna Parpaglia; Vittorio Anania; Nicola Glorioso; C Chao; C Wang; Julie Chao
Sexual dimorphism of cardiovascular responses to early blockade of bradykinin receptors.
Hypertension 1996;27(3 Pt 2):746-51.
1995: Paolo Madeddu; Vittorio Anania; Maria Vittoria Varoni; Paolo Pinna Parpaglia; Maria Piera Demontis; M C Fattaccio; Domenico Palomba; David M Pollock; Nicola Glorioso
Prevention by blockade of angiotensin subtype1-receptors of the development of genetic hypertension but not its heritability.
British journal of pharmacology 1995;115(4):557-62.
1995: Paolo Madeddu; Paolo Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; M C Fattaccio; Vittorio Anania; Nicola Glorioso
Effects of kinin blockade on the blood pressure of salt-loaded pregnant rats.
Hypertension 1995;25(4 Pt 2):823-7.
1995: Paolo Madeddu; Paolo Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; M C Fattaccio; Vittorio Anania; Nicola Glorioso
Early blockade of bradykinin B2-receptors alters the adult cardiovascular phenotype in rats.
Hypertension 1995;25(3):453-9.
1995: Nicola Glorioso; Giancarlo Tonolo; Chiara Troffa; Aldo Soro; Paolo Manunta; Paolo Madeddu; G Sabino; P Pinna-Parpaglia; G Realdi
Recognition of markers of response to potassium-canrenoate in essential hypertension.
Steroids 1995;60(1):105-9.
1994: Paolo Madeddu; P Pinna-Parpaglia; Maria Vittoria Varoni; Maria Piera Demontis; M C Fattaccio; Vittorio Anania; Nicola Glorioso
Chronic inhibition of bradykinin receptors alters cardiovascular function in rats with an excess of circulating vasoconstrictors.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(8):1985-93.
1994: Paolo Madeddu; Maria Vittoria Varoni; Maria Piera Demontis; M C Fattaccio; Paolo Pinna Parpaglia; Nicola Glorioso
A kallikrein-like enzyme in the aorta of normotensive and hypertensive rats.
Hypertension 1994;23(6 Pt 2):899-902.
1994: Paolo Madeddu; Paolo Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; M C Fattaccio; Nicola Glorioso
Chronic inhibition of bradykinin B2-receptors enhances the slow vasopressor response to angiotensin II.
Hypertension 1994;23(5):646-52.
1994: Paolo Madeddu; Nicola Glorioso; Maria Vittoria Varoni; Maria Piera Demontis; M C Fattaccio; Vittorio Anania
Cardiovascular effects of brain kinin receptor blockade in spontaneously hypertensive rats.
Hypertension 1994;23(1 Suppl):I189-92.
1993: Paolo Madeddu
Receptor antagonists of bradykinin: a new tool to study the cardiovascular effects of endogenous kinins.
Pharmacological research : the official journal of the Italian Pharmacological Society 1993;28(2):107-28.
1993: Paolo Madeddu; Paolo Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; M C Fattaccio; Giancarlo Tonolo; Chiara Troffa; Nicola Glorioso
Bradykinin B2-receptor blockade facilitates deoxycorticosterone-salt hypertension.
Hypertension 1993;21(6 Pt 2):980-4.
1993: Giancarlo Tonolo; Aldo Soro; Paolo Madeddu; Chiara Troffa; Maria Grazia Melis; G Patteri; Paolo Pinna Parpaglia; G Sabino; Mario Maioli; Nicola Glorioso
Effect of chronic intracerebroventricular dexamethasone on blood pressure in normotensive rats.
The American journal of physiology 1993;264(6 Pt 1):E843-7.
1993: Paolo Madeddu; Tiziano Gherli; P P Bacciu; M Maioli; Nicola Glorioso
A kallikrein-like enzyme in human vascular tissue.
American journal of hypertension 1993;6(5 Pt 1):344-8.
1993: Paolo Madeddu; Maria Piera Demontis; Maria Vittoria Varoni; M C Fattaccio; A Palmieri; Vittorio Anania
Verapamil prevents the acute hypertensive response to intracerebroventricular cadmium in conscious normotensive rats.
American journal of hypertension 1993;6(3 Pt 1):193-7.
1993: Paolo Madeddu; Vittorio Anania; Paolo Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; M C Fattaccio; Nicola Glorioso
Chronic kinin receptor blockade induces hypertension in deoxycorticosterone-treated rats.
British journal of pharmacology 1993;108(3):651-7.
1993: Nicola Glorioso; Maria Grazia Melis; Paolo Manunta; Chiara Troffa; Giancarlo Tonolo; Aldo Soro; Paolo Madeddu; A Pazzola; F Pala; Daniele Cusi
Different sensitivity to hydrochlorothiazide and to potassium-canrenoate among essential hypertensive patients.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1993;15 Suppl 1():187-96.
1992: Paolo Madeddu; Vittorio Anania; Paolo Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; G Pisanu; Chiara Troffa; Giancarlo Tonolo; Nicola Glorioso
Effects of Hoe 140, a bradykinin B2-receptor antagonist, on renal function in conscious normotensive rats.
British journal of pharmacology 1992;106(2):380-6.
1992: Paolo Madeddu; Vittorio Anania; S Alagna; Chiara Troffa; Paolo Pinna Parpaglia; Giancarlo Tonolo; Maria Piera Demontis; Maria Vittoria Varoni; C Fattaccio; Nicola Glorioso
Role of brain kallikrein-kinin system in regulation of adrenocorticotropin release.
The American journal of physiology 1992;262(3 Pt 1):E312-8.
1992: Paolo Madeddu; Nicola Glorioso; P Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; M C Fattaccio; G Sabino; G Pisanu; G Patteri; Vittorio Anania
Kinin antagonist blunts the diuretic effect of furosemide in deoxycorticosterone-treated rats.
Agents and actions. Supplements 1992;38 ( Pt 3)():156-62.
1992: Paolo Madeddu; Vittorio Anania; Paolo Pinna Parpaglia; Maria Piera Demontis; Maria Vittoria Varoni; M C Fattaccio; Nicola Glorioso
Regional hemodynamic effects of a kinin antagonist in awake normotensive rats.
Agents and actions. Supplements 1992;38 ( Pt 3)():149-55.
1991: Paolo Madeddu; Nicola Glorioso; Mario Maioli; Maria Piera Demontis; Maria Vittoria Varoni; Vittorio Anania; W Xiong; K Chai; Julie Chao
Regulation of rat renal kallikrein expression by estrogen and progesterone.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S244-5.
1991: Paolo Madeddu; Vittorio Anania; Paolo Pinna Parpaglia; Chiara Troffa; A Pazzola; Aldo Soro; Paolo Manunta; Giancarlo Tonolo; Maria Piera Demontis; Maria Vittoria Varoni
Endothelin-1-induced renal vasoconstriction is blunted by enalaprilat and enhanced by EDRF antagonist in awake normotensive rats.
Clinical and investigative medicine. Médecine clinique et experimentale 1991;14(6):600-6.
1991: Chiara Troffa; Giancarlo Tonolo; Paolo Manunta; A Pazzola; Aldo Soro; Paolo Madeddu; F Pala; Maria Grazia Melis; P PinnaParpaglia; G Patteri
Prorenin is present in human red blood cells.
Canadian journal of physiology and pharmacology 1991;69(9):1394-7.
1991: Paolo Madeddu; P Ena; Paolo Pinna Parpaglia; G Patteri; S Bacciu; Mario Maioli; Nicola Glorioso
Depressed urinary excretion of epidermal growth factor in psoriasis.
American journal of nephrology 1991;11(4):313-7.
1990: Paolo Madeddu; X P Yang; Vittorio Anania; Chiara Troffa; A Pazzola; Aldo Soro; Paolo Manunta; Giancarlo Tonolo; Maria Piera Demontis; Maria Vittoria Varoni
Efficacy of nifedipine to prevent systemic and renal vasoconstrictor effects of endothelin.
The American journal of physiology 1990;259(2 Pt 2):F304-11.
1990: Paolo Madeddu; F Pala; Chiara Troffa; P Pinna Parpaglia; A Pazzola; Aldo Soro; Paolo Manunta; Giancarlo Tonolo; Maria Grazia Melis; Maria Piera Demontis
[Protective effect of a calcium antagonist against renal vasoconstriction induced by endothelin in the normotensive rat].
Bollettino della Società italiana di biologia sperimentale 1990;66(7):671-8.
1990: Chiara Troffa; Giancarlo Tonolo; Paolo Manunta; P Pinna Parpaglia; Paolo Madeddu; Maria Grazia Melis; Aldo Soro; F Pala; A Pazzola; G Patteri
[Effect of chronic enalapril treatment on prorenin, renin and sex hormones during the menstrual cycle in patients with essential hypertension].
Bollettino della Società italiana di biologia sperimentale 1990;66(7):663-70.
1990: Maria Grazia Melis; Chiara Troffa; Paolo Manunta; P Pinna Parpaglia; Aldo Soro; F Pala; Paolo Madeddu; A Pazzola; Giancarlo Tonolo; G Patteri
[Effect of menstrual cycle hormones on cation transport in the red-cell membrane].
Bollettino della Società italiana di biologia sperimentale 1990;66(7):679-84.
1990: Paolo Madeddu; Nicola Glorioso; Aldo Soro; Giancarlo Tonolo; Paolo Manunta; Chiara Troffa; Maria Piera Demontis; Maria Vittoria Varoni; Vittorio Anania
Brain kinins are responsible for the pressor effect of intracerebroventricular captopril in spontaneously hypertensive rats.
Hypertension 1990;15(4):407-12.
1990: Paolo Madeddu; Nicola Glorioso; Aldo Soro; Paolo Manunta; Chiara Troffa; Giancarlo Tonolo; M Grazia Melis; A Pazzola
Effect of a kinin antagonist on renal function and haemodynamics during alterations in sodium balance in conscious normotensive rats.
Clinical science (London, England : 1979) 1990;78(2):165-8.
1989: Nicola Glorioso; Chiara Troffa; Giancarlo Tonolo; Paolo Manunta; Paolo Madeddu; Maria Grazia Melis; A Pazzola; F Pala; Mario Maioli; P Mameli
Activation of human prorenin by lipidic constituents of the cell membrane.
American journal of hypertension 1989;2(12 Pt 1):920-3.
1989: Nicola Glorioso; Chiara Troffa; Giancarlo Tonolo; Maria Grazia Melis; Paolo Manunta; Aldo Soro; Paolo Madeddu; A Pazzola; F Pàla
Stimulation of plasma inactive renin by dexamethasone in the cat.
The American journal of physiology 1989;257(6 Pt 1):E879-84.
1989: Chiara Troffa; Giancarlo Tonolo; Aldo Soro; Paolo Manunta; Maria Grazia Melis; A Pazzola; F Pala; Paolo Madeddu; S Alagna; A Masala
Circulating prorenin and renin in response to intravenous adrenocorticotrophic hormone in essential hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(6):S226-7.
1989: Giancarlo Tonolo; Aldo Soro; V Scardaccio; Chiara Troffa; A Pazzola; Paolo Manunta; Maria Grazia Melis; F Pala; Paolo Madeddu; P P Rovasio
Correlates of atrial natriuretic factor in chronic renal failure.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(6):S238-9.
1989: Paolo Madeddu; Chiara Troffa; Nicola Glorioso; A Pazzola; Aldo Soro; Paolo Manunta; Giancarlo Tonolo; Maria Piera Demontis; Maria Vittoria Varoni; Vittorio Anania
Effect of endothelin on regional hemodynamics and renal function in awake normotensive rats.
Journal of cardiovascular pharmacology 1989;14(6):818-25.
1989: Chiara Troffa; Giancarlo Tonolo; Paolo Manunta; A Pazzola; Maria Grazia Melis; F Pala; Aldo Soro; Paolo Madeddu; Nicola Glorioso
[Possible activation of human prorenin by contact with the cell membrane].
Bollettino della Società italiana di biologia sperimentale 1989;65(11):1017-23.
1989: Paolo Manunta; Maria Grazia Melis; Aldo Soro; A Pazzola; Chiara Troffa; S Motzo; F Pala; Paolo Madeddu; Giancarlo Tonolo; Nicola Glorioso
[Erythrocyte cation transport in arterial hypertension: interrelation with the renin-angiotensin-aldosterone system and the atrial natriuretic factor].
Bollettino della Società italiana di biologia sperimentale 1989;65(11):1009-16.
1989: S Alagna; Paolo Dessì-Fulgheri; A Masala; Paolo Madeddu; P P Rovasio; Nicola Glorioso; Alessandro Rappelli
Evaluation of anterior pituitary function in hypertensive patients following inhibition of angiotensin II generation.
Journal of endocrinological investigation 1989;12(9):611-5.
1989: Giancarlo Tonolo; A M Richards; Paolo Manunta; Chiara Troffa; A Pazzola; Paolo Madeddu; A Towrie; Robert Fraser; Nicola Glorioso
Low-dose infusion of atrial natriuretic factor in mild essential hypertension.
Circulation 1989;80(4):893-902.
1988: Paolo Madeddu; P Ena; Nicola Glorioso; Decio Cerimele; A Rappelli
High prevalence of microproteinuria, an early index of renal impairment, in patients with diffuse psoriasis.
Nephron 1988;48(3):222-5.
1988: Nicola Glorioso; Paolo Manunta; Chiara Troffa; A Pazzola; Aldo Soro; F Pala; Maria Grazia Melis; Paolo Madeddu; Giancarlo Tonolo
Effects of nitrendipine on blood pressure, renin-angiotensin system, and kidney function in essential hypertension.
Journal of cardiovascular pharmacology 1988;12 Suppl 4():S142-5.
1987: Paolo Madeddu; M Oppes; S Rubattu; P Dessi'-Fulgheri; Nicola Glorioso; Aldo Soro; Alessandro Rappelli
Role of renal kallikrein in modulating the antihypertensive effect of a single oral dose of captopril in normal- and low-renin essential hypertensives.
Journal of hypertension 1987;5(6):645-8.
1987: Paolo Madeddu; M Oppes; Aldo Soro; P Dessi'-Fulgheri; Nicola Glorioso; F Bandiera; Paolo Manunta; S Rubattu; Alessandro Rappelli
The effects of aprotinin, a kallikrein inhibitor, on renin release and urinary sodium excretion in mild essential hypertensives.
Journal of hypertension 1987;5(5):581-6.
1987: Paolo Madeddu; M Oppes; Aldo Soro; P Dessi'-Fulgheri; Nicola Glorioso; F Bandiera; Paolo Manunta; S Rubattu; Chiara Troffa; Giancarlo Tonolo
Natriuretic effect of acute nifedipine administration is not mediated by the renal kallikrein-kinin system.
Journal of cardiovascular pharmacology 1987;9(5):536-40.
1987: Paolo Madeddu; M Oppes; S Rubattu; F Bandiera; P Dessi'-Fulgheri; Nicola Glorioso; Aldo Soro; M Chiara-Troffa; Alessandro Rappelli
Urinary kallikrein excretion can predict the blood pressure response to a single oral dose of captopril.
Agents and actions. Supplements 1987;22():321-8.
1987: Paolo Dessì-Fulgheri; F Cocco; Nicola Glorioso; F Bandiera; Paolo Madeddu; Alessandro Rappelli
Immunoradiometric assay of active renin in human plasma: comparison with plasma renin activity.
Clinical and experimental hypertension. Part A, Theory and practice 1987;9(8-9):1383-90.
1987: Paolo Madeddu; M Oppes; S Rubattu; F Bandiera; P Dessi-Fulgheri; Nicola Glorioso; Aldo Soro; M C Troffa; Alessandro Rappelli
Relation between urinary kallikrein excretion and blood pressure response to a single oral dose of captopril.
Clinical and experimental hypertension. Part A, Theory and practice 1987;9(2-3):615-21.
1987: Nicola Glorioso; Paolo Dessì-Fulgheri; S Alagna; S Rubattu; Aldo Soro; Paolo Madeddu; F Bandiera; A Masala; P P Rovasio; Alessandro Rappelli
Angiotensin converting enzyme inhibition reduces ACTH release due to hypoglycaemia.
Clinical and experimental hypertension. Part A, Theory and practice 1987;9(2-3):665-70.
1987: Paolo Dessì-Fulgheri; F Bandiera; S Rubattu; F Cocco; Paolo Madeddu; M Oppes; Giancarlo Tonolo; Nicola Glorioso; Alessandro Rappelli
Comparison of sublingual and oral captopril in hypertension.
Clinical and experimental hypertension. Part A, Theory and practice 1987;9(2-3):593-7.
1987: Paolo Dessì-Fulgheri; A Pacifico; F Bandiera; S Rubattu; Paolo Madeddu; Nicola Glorioso; M Maioli; Giuseppe Delitala; Paolo Tomasi; Alessandro Rappelli
Effect of nifedipine and verapamil on carbohydrate metabolism in hypertensive patients with impaired glucose tolerance.
Journal of cardiovascular pharmacology 1987;10 Suppl 10():S195-8.
1987: Paolo Madeddu; M Oppes; Aldo Soro; P Dessi'-Fulgheri; Nicola Glorioso; F Manunta; S Rubatti; Alessandro Rappelli
The effects of aprotinin, a glandular kallikrein inhibitor, on renin release and urinary sodium excretion in mild essential hypertensives.
Agents and actions. Supplements 1987;22():373-80.
1986: Paolo Madeddu; P Ena; Paolo Dessì-Fulgheri; Nicola Glorioso; Decio Cerimele; A Rappelli
Captopril-induced proteinuria in hypertensive psoriatic patients.
Nephron 1986;44(4):358-60.
1986: Alessandro Rappelli; Nicola Glorioso; Paolo Madeddu; Paolo Dessì-Fulgheri; C Leoni; C Fiori; G B Manca; G Sanna; F Arzilli; R Pedrinelli
Renal vein renin in renovascular hypertension: the experience of two Italian centers.
Nephron 1986;44 Suppl 1():12-6.
1985: Paolo Madeddu; M Oppes; S Rubattu; Giancarlo Tonolo; Paolo Dessì-Fulgheri; Nicola Glorioso; Alessandro Rappelli
Prokallikrein and kallikrein inhibitors in human urine.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1985;3(3):S283-6.
1985: Paolo Dessì-Fulgheri; S Alagna; Paolo Madeddu; Nicola Glorioso; A Masala; P P Rovasio; C Leoni; Alessandro Rappelli
Blunted adrenocorticotrophic hormone release during captopril treatment.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1985;3(2):S125-7.
1985: P Ena; Paolo Madeddu; Nicola Glorioso; Decio Cerimele; A Rappelli
High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotensin system in psoriatic patients.
Acta cardiologica 1985;40(2):199-205.
1984: Nicola Glorioso; Paolo Madeddu; Paolo Dessì-Fulgheri; M Oppes; Giancarlo Tonolo; F Bandiera; G Manca; Alessandro Rappelli
[Long-term therapeutic efficacy of captopril in the treatment of essential and secondary hypertension].
Minerva cardioangiologica 1984;32(7-8):467-71.
1983: Nicola Glorioso; Paolo Dessì-Fulgheri; Paolo Madeddu; M Palermo; F Urigo; S Rovasio; Giovanni Battista Meloni; Alessandro Rappelli
[Percutaneous transluminal dilatation in the therapy of nephrovascular hypertension].
Cardiologia (Rome, Italy) 1983;28(6):539-52.
1983: Nicola Glorioso; Paolo Madeddu; P Dessi'-Fulgheri; G Fois; F Meloni; F Bandiera; Giancarlo Tonolo; Alessandro Rappelli
Trypsin-activatable inactive renin in rat plasma.
Clinical science (London, England : 1979) 1983;64(2):137-40.
1982: Nicola Glorioso; Paolo Dessì-Fulgheri; Paolo Madeddu; G Fois; M Palermo; F Cocco; S Dettori; Alessandro Rappelli
Active and inactive renin after a single dose of captopril in hypertensive patients.
The American journal of cardiology 1982;49(6):1552-4.
1982: Nicola Glorioso; Paolo Madeddu; P D Fulgheri; F Cocco; G Sanna; C Fiori; S Dettori; Alessandro Rappelli
In-vivo activation of circulating inactive renin by the ischemic kidney in man.
Clinical and experimental hypertension. Part A, Theory and practice 1982;4(6):951-61.
1982: Nicola Glorioso; Paolo Dessì-Fulgheri; Paolo Madeddu; F Urigo; Giancarlo Tonolo; M Oppes; M Palermo; Alessandro Rappelli
Active and inactive renin during acute reduction of renal perfusion pressure in essential hypertensives.
Clinical and experimental hypertension. Part A, Theory and practice 1982;4(11-12):2293-302.
1982: Alessandro Rappelli; Paolo Dessì-Fulgheri; Paolo Madeddu; C Leoni; C Fiori; F Cocco; G Sanna; Nicola Glorioso
Plasma active and inactive renin and urinary kallikrein in normal subjects in response to hydrochlorothiazide, spironolactone or aldosterone administration.
Clinical and experimental hypertension. Part A, Theory and practice 1982;4(11-12):2273-83.
1982: Nicola Glorioso; Paolo Madeddu; Paolo Dessì-Fulgheri; Vittorio Anania; F Meloni; G Fois; F Bandiera; Alessandro Rappelli
Studies on trypsin activation of inactive renin in rat plasma.
Clinical and experimental hypertension. Part A, Theory and practice 1982;4(11-12):2203-12.
1982: Nicola Glorioso; P Dessi' Fulgheri; Paolo Madeddu; Alessandro Rappelli
Persistence of unilateral secretion and contralateral renin suppression after successful percutaneous transluminal dilatation in a normotensive patient.
Acta cardiologica 1982;37(6):451-4.
1981: Alessandro Rappelli; P Dessi'-Fulgheri; Paolo Madeddu; F Meloni; C Fiori; G Sanna; Nicola Glorioso
Optimum tryptic activation of inactive renin in human plasma is independent of endogenous anti-tryptic activity.
Clinical science (London, England : 1979) 1981;61 Suppl 7():303s-305s.
1981: Nicola Glorioso; Paolo Madeddu; Paolo Dessì-Fulgheri; F Meloni; G Fois; M Palermo; Alessandro Rappelli
A scoring system improving both sensitivity and specificity of screening tests for renovascular disease.
Giornale italiano di cardiologia 1981;11(11):1684-91.
1981: Alessandro Rappelli; Nicola Glorioso; Paolo Madeddu; Paolo Dessì-Fulgheri; G Fois; L Lenguini; F Meloni; M Palermo
Trypsin activation of inactive renin in human plasma. An assessment of some methodological aspects.
Clinical and experimental hypertension 1981;3(2):299-318.
1981: Nicola Glorioso; Paolo Madeddu; Paolo Dessì-Fulgheri; G Sanna; C Fiori; S Dettori; F Cocco; Alessandro Rappelli
[Role of renin profile and age in the choice of the therapeutic approach of arterial hypertension (author's transl)].
Giornale italiano di cardiologia 1981;11(12):2117-25.
1980: Nicola Glorioso; Paolo Madeddu; Paolo Dessì-Fulgheri; F Meloni; M Palermo; C Fiori; Alessandro Rappelli
[Significance of the saralasin infusion test in the diagnosis of arterial hypertension].
Bollettino della Società italiana di cardiologia 1980;25(9):1035-46.
1980: Nicola Glorioso; Paolo Dessì-Fulgheri; Paolo Madeddu; G Fois; L Lenguini; G Sanna; F Urigo; P Biglioli; S M Giulini; Alessandro Rappelli
[Pre- and post-operative evaluation of the renin-angiotensin system in nephrovascular hypertension].
Bollettino della Società italiana di cardiologia 1980;25(9):1021-33.
1980: Nicola Glorioso; Paolo Dessì-Fulgheri; Paolo Madeddu; G Fois; L Lenguini; F G Cocco; Alessandro Rappelli
[Methodology of renal vein renin study: comparison between simultaneous and sequential sampling (author's transl)].
Giornale italiano di cardiologia 1980;10(9):1186-91.