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Nicolaos Madias

Research Profile

Chemicals & Drugs

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Acid-Base Equilibrium

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TOP 3
Dmitry Y Shchekochikhin; Bertrand L Jaber; Joann Lindenfeld; Lori Lyn Price; Robert W Schrier; Nicolaos E Madias
Outcome differences in community- versus hospital-acquired hyponatremia in patients with a diagnosis of heart failure.
Paweena Susantitaphong; Ethan M Balk; Somchai Eiam-Ong; Nicolaos E Madias; Kamal Sewaralthahab; Bertrand L Jaber
Efficacy and safety of combined vs. single renin-angiotensin-aldosterone system blockade in chronic kidney disease: a meta-analysis.
Jeffrey A Kraut; Nicolaos E Madias
Treatment of acute metabolic acidosis: a pathophysiologic approach.

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All Publications

2013: Dmitry Y Shchekochikhin; Bertrand L Jaber; Joann Lindenfeld; Lori Lyn Price; Robert W Schrier; Nicolaos E Madias
Outcome differences in community- versus hospital-acquired hyponatremia in patients with a diagnosis of heart failure.
Circulation. Heart failure 2013;6(3):379-86.
2013: Paweena Susantitaphong; Ethan M Balk; Somchai Eiam-Ong; Nicolaos E Madias; Kamal Sewaralthahab; Bertrand L Jaber
Efficacy and safety of combined vs. single renin-angiotensin-aldosterone system blockade in chronic kidney disease: a meta-analysis.
American journal of hypertension 2013;26(3):424-41.
2012: Jeffrey A Kraut; Nicolaos E Madias
Treatment of acute metabolic acidosis: a pathophysiologic approach.
Nature reviews. Nephrology 2012;8(10):589-601.
2012: Horacio J Adrogué; Nicolaos E Madias
The challenge of hyponatremia.
Journal of the American Society of Nephrology : JASN 2012;23(7):1140-8.
2012: Paweena Susantitaphong; Ethan M Balk; Ioannis Koulouridis; Nicolaos E Madias; Bertrand L Jaber
Effect of frequent or extended hemodialysis on cardiovascular parameters: a meta-analysis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2012;59(5):689-99.
2012: Jeffrey A Kraut; Nicolaos E Madias
Differential diagnosis of nongap metabolic acidosis: value of a systematic approach.
Clinical journal of the American Society of Nephrology : CJASN 2012;7(4):671-9.
2012: Pantelis A Sarafidis; Pavlos Nikolaidis; Panagiotis I Georgianos; Georgios Germanidis; Constantinos Giavroglou; Anastasios N Lasaridis; Nicolaos E Madias
Hypertension and symptomatic hypokalemia in a patient with simultaneous unilateral stenoses of intrarenal arteries and mesangioproliferative glomerulonephritis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2012;59(3):434-8.
2012: Paweena Susantitaphong; Kamal Sewaralthahab; Ethan M Balk; Bertrand L Jaber; Nicolaos E Madias
Short- and long-term effects of alkali therapy in chronic kidney disease: a systematic review.
American journal of nephrology 2012;35(6):540-7.
2011: Bertrand L Jaber; Leena Almarzouqi; Ethan M Balk; Lea Borgi; Victor Seabra; Nicolaos E Madias
Short-term efficacy and safety of vasopressin receptor antagonists for treatment of hyponatremia.
The American journal of medicine 2011;124(10):977.e1-9.
2011: Jeffrey A Kraut; Nicolaos E Madias
Consequences and therapy of the metabolic acidosis of chronic kidney disease.
Pediatric nephrology (Berlin, Germany) 2011;26(1):19-28.
2010: Nicolaos E Madias
Renal acidification responses to respiratory acid-base disorders.
Journal of nephrology 2010;23 Suppl 16():S85-91.
2010: Demetrios V Vlahakos; Katerina P Marathias; Nicolaos E Madias
The role of the renin-angiotensin system in the regulation of erythropoiesis.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2010;56(3):558-65.
2010: Horacio J Adrogué; Nicolaos E Madias
Secondary responses to altered acid-base status: the rules of engagement.
Journal of the American Society of Nephrology : JASN 2010;21(6):920-3.
2010: Jeffrey A Kraut; Nicolaos E Madias
Metabolic acidosis: pathophysiology, diagnosis and management.
Nature reviews. Nephrology 2010;6(5):274-85.
2010: Ron Wald; Bertrand L Jaber; Lori Lyn Price; Ashish Upadhyay; Nicolaos E Madias
Impact of hospital-associated hyponatremia on selected outcomes.
Archives of internal medicine 2010;170(3):294-302.
2009: Horacio J Adrogué; F John Gennari; John H Galla; Nicolaos E Madias
Assessing acid-base disorders.
Kidney international 2009;76(12):1239-47.
2009: Horacio J Adrogué; Nicolaos E Madias
Shared primacy of sodium and potassium on cardiovascular risk.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2009;54(4):598-601.
2009: Nicolaos E Madias
A 56-year-old man in the intensive care unit with a complex acid-base disturbance.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2009;54(3):561-6.
2009: Alexey Y Kolyada; Hocine Tighiouart; Mary C Perianayagam; Orfeas Liangos; Nicolaos E Madias; Bertrand L Jaber
A genetic variant of hypoxia-inducible factor-1alpha is associated with adverse outcomes in acute kidney injury.
Kidney international 2009;75(12):1322-9.
2009: Ashish Upadhyay; Bertrand L Jaber; Nicolaos E Madias
Epidemiology of hyponatremia.
Seminars in nephrology 2009;29(3):227-38.
2008: Alexey Y Kolyada; Orfeas Liangos; Nicolaos E Madias; Bertrand L Jaber
Protective effect of erythropoietin against radiocontrast-induced renal tubular epithelial cell injury.
American journal of nephrology 2008;28(2):203-9.
2007: Nicolaos E Madias
Effects of tolvaptan, an oral vasopressin V2 receptor antagonist, in hyponatremia.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2007;50(2):184-7.
2007: Horacio J Adrogué; Nicolaos E Madias
Sodium and potassium in the pathogenesis of hypertension.
The New England journal of medicine 2007;356(19):1966-78.
2007: Jeffrey A Kraut; Nicolaos E Madias
Serum anion gap: its uses and limitations in clinical medicine.
Clinical journal of the American Society of Nephrology : CJASN 2007;2(1):162-74.
2007: George Liamis; Dimitrios S Christidis; George Alexandridis; Eleni Bairaktari; Nicolaos E Madias; Moses Elisaf
Uric acid homeostasis in the evaluation of diuretic-induced hyponatremia.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2007;55(1):36-44.
2006: Marie Anne Sosa; Ethan M Balk; Joseph Lau; Orfeas Liangos; Vaidyanathapuram S Balakrishnan; Nicolaos E Madias; Brian J G Pereira; Bertrand L Jaber
A systematic review of the effect of the Excebrane dialyser on biomarkers of lipid peroxidation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(10):2825-33.
2006: Ashish Upadhyay; Bertrand L Jaber; Nicolaos E Madias
Incidence and prevalence of hyponatremia.
The American journal of medicine 2006;119(7 Suppl 1):S30-5.
2006: Mary C Perianayagam; Nicolaos E Madias; Brian J G Pereira; Bertrand L Jaber
CREB transcription factor modulates Bcl2 transcription in response to C5a in HL-60-derived neutrophils.
European journal of clinical investigation 2006;36(5):353-61.
2006: Bertrand L Jaber; Nicolaos E Madias
Benazepril for advanced chronic renal insufficiency.
The New England journal of medicine 2006;354(14):1530-1; author reply 1530-1.
2006: Bertrand L Jaber; Luis F Lobon; Nicolaos E Madias
The serotonin syndrome complicating co-prescription of paroxetine and clarithromycin.
The American journal of medicine 2006;119(4):e3.
2006: Orfeas Liangos; Ambreen Gul; Nicolaos E Madias; Bertrand L Jaber
Long-term management of the tunneled venous catheter.
Seminars in dialysis 2006;19(2):158-64.
2006: John E Madias; Nicolaos E Madias
Reversible attenuation of the ECG voltage due to peripheral edema associated with treatment with a COX-2 inhibitor.
Congestive heart failure (Greenwich, Conn.) 2006;12(1):46-50.
2005: Bertrand L Jaber; Nicolaos E Madias
Progression of chronic kidney disease: can it be prevented or arrested?
The American journal of medicine 2005;118(12):1323-30.
2005: Bertrand L Jaber; Nicolaos E Madias
Atorvastatin in patients with type 2 diabetes mellitus undergoing dialysis.
The New England journal of medicine 2005;353(17):1858-60; author reply 1858-60.
2005: Bertrand L Jaber; Nicolaos E Madias
C-reactive protein levels and outcomes after statin therapy.
The New England journal of medicine 2005;352(15):1603-5; author reply 1603-5.
2004: Man S Oh; Jaime Uribarri; Jordan Weinstein; Martin Schreiber; Kamel S Kamel; Jeffrey A Kraut; Nicolaos E Madias; Melvin E Laski
What unique acid-base considerations exist in dialysis patients?
Seminars in dialysis 2004;17(5):351-64.
2004: Horacio J Adrogué; Nicolaos E Madias
PCO2 and [K+]p in metabolic acidosis: certainty for the first and uncertainty for the other.
Journal of the American Society of Nephrology : JASN 2004;15(6):1667-8.
2003: Demetrios V Vlahakos; Katerina P Marathias; Basil Agroyannis; Nicolaos E Madias
Posttransplant erythrocytosis.
Kidney international 2003;63(4):1187-94.
2003: Nicolaos E Madias; Horacio J Adrogué
Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung.
Nephron. Physiology 2003;93(3):p61-6.
2001: A Y Kolyada; A Fedtsov; Nicolaos E Madias
3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors upregulate inducible NO synthase expression and activity in vascular smooth muscle cells.
Hypertension 2001;38(5):1024-9.
2001: A Y Kolyada; Nicolaos E Madias
Transcriptional regulation of the human iNOS gene by IL-1beta in endothelial cells.
Molecular medicine (Cambridge, Mass.) 2001;7(5):329-43.
2001: Jeffrey A Kraut; Nicolaos E Madias
Approach to patients with acid-base disorders.
Respiratory care 2001;46(4):392-403.
2000: John E Madias; B Shah; G Chintalapally; G Chalavarya; Nicolaos E Madias
Admission serum potassium in patients with acute myocardial infarction: its correlates and value as a determinant of in-hospital outcome.
Chest 2000;118(4):904-13.
2000: Horacio J Adrogué; Nicolaos E Madias
Hyponatremia.
The New England journal of medicine 2000;342(21):1581-9.
2000: Horacio J Adrogué; Nicolaos E Madias
Hypernatremia.
The New England journal of medicine 2000;342(20):1493-9.
1998: Horacio J Adrogué; Nicolaos E Madias
Management of life-threatening acid-base disorders. Second of two parts.
The New England journal of medicine 1998;338(2):107-11.
1998: Horacio J Adrogué; Nicolaos E Madias
Management of life-threatening acid-base disorders. First of two parts.
The New England journal of medicine 1998;338(1):26-34.
1997: Bertrand L Jaber; Nicolaos E Madias
Marked dilutional acidosis complicating management of right ventricular myocardial infarction.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1997;30(4):561-7.
1997: Horacio J Adrogué; Nicolaos E Madias
Aiding fluid prescription for the dysnatremias.
Intensive care medicine 1997;23(3):309-16.
1996: A Y Kolyada; N Savikovsky; Nicolaos E Madias
Transcriptional regulation of the human iNOS gene in vascular-smooth-muscle cells and macrophages: evidence for tissue specificity.
Biochemical and biophysical research communications 1996;220(3):600-5.
1995: A Y Kolyada; C A Johns; Nicolaos E Madias
Role of C/EBP proteins in hepatic and vascular smooth muscle transcription of human NHE1 gene.
The American journal of physiology 1995;269(6 Pt 1):C1408-16.
1995: V J Canzanello; J A Kraut; M F Holick; C Johns; C C Liu; Nicolaos E Madias
Effect of chronic respiratory acidosis on calcium metabolism in the rat.
The Journal of laboratory and clinical medicine 1995;126(1):81-7.
1994: J C da Silva; X J Shi; C A Johns; Douglas M Jefferson; Shelley A Grubman; Nicolaos E Madias; R D Perrone
Experimental renal failure in the rat modulates cardiac Na,K-ATPase alpha 2 mRNA but not protein.
Journal of the American Society of Nephrology : JASN 1994;5(1):27-35.
1994: A Y Kolyada; T V Lebedeva; C A Johns; Nicolaos E Madias
Proximal regulatory elements and nuclear activities required for transcription of the human Na+/H+ exchanger (NHE-1) gene.
Biochimica et biophysica acta 1994;1217(1):54-64.
1993: S Eiam-Ong; S A Hilden; C A Johns; Nicolaos E Madias
Stimulation of basolateral Na(+)-HCO3- cotransporter by angiotensin II in rabbit renal cortex.
The American journal of physiology 1993;265(2 Pt 2):F195-203.
1992: R D Perrone; Nicolaos E Madias; A S Levey
Serum creatinine as an index of renal function: new insights into old concepts.
Clinical chemistry 1992;38(10):1933-53.
1992: S Eiam-Ong; S A Hilden; A J King; C A Johns; Nicolaos E Madias
Endothelin-1 stimulates the Na+/H+ and Na+/HCO3- transporters in rabbit renal cortex.
Kidney international 1992;42(1):18-24.
1991: S A Hilden; Nicolaos E Madias
Effect of sulfhydryl compounds on ATP-stimulated H+ transport and Cl- uptake in rabbit renal cortical endosomes.
The Journal of membrane biology 1991;124(2):139-49.
1991: J C Da Silva Júnior; R D Perrone; C A Johns; Nicolaos E Madias
Rat kidney band 3 mRNA modulation in chronic respiratory acidosis.
The American journal of physiology 1991;260(2 Pt 2):F204-9.
1991: D V Vlahakos; V J Canzanello; Michael P. Madaio; Nicolaos E Madias
Enalapril-associated anemia in renal transplant recipients treated for hypertension.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1991;17(2):199-205.
1990: V J Canzanello; M Bodvarsson; J A Kraut; C A Johns; E Slatopolsky; Nicolaos E Madias
Effect of chronic respiratory acidosis on urinary calcium excretion in the dog.
Kidney international 1990;38(3):409-16.
1990: S A Hilden; K B Ghoshroy; Nicolaos E Madias
Na(+)-H+ exchange, but not Na(+)-K(+)-ATPase, is present in endosome-enriched microsomes from rabbit renal cortex.
The American journal of physiology 1990;258(5 Pt 2):F1311-9.
1990: Nicolaos E Madias; J J Cohen; Horacio J Adrogué
Influence of acute and chronic respiratory alkalosis on preexisting chronic metabolic alkalosis.
The American journal of physiology 1990;258(3 Pt 2):F479-85.
1990: S A Hilden; Nicolaos E Madias
Stimulation of canine kidney BBMV ATPase activity by acidic pH in the presence of Zn2+: an ATPase activity distinct from transport ATPases and alkaline phosphatase that may be an ecto-ATPase.
Membrane biochemistry 1990;9(1):69-81.
1989: S A Hilden; Nicolaos E Madias
H+/Ca2+ exchange in rabbit renal cortical endosomes.
The Journal of membrane biology 1989;112(2):131-8.
1989: Horacio J Adrogué; M N Rashad; A B Gorin; J Yacoub; Nicolaos E Madias
Arteriovenous acid-base disparity in circulatory failure: studies on mechanism.
The American journal of physiology 1989;257(6 Pt 2):F1087-93.
1989: S A Hilden; C A Johns; Nicolaos E Madias
Adaptation of rabbit renal cortical Na+-H+ exchange activity in chronic hypocapnia.
The American journal of physiology 1989;257(4 Pt 2):F615-22.
1989: S A Hilden; C A Johns; William B Guggino; Nicolaos E Madias
Techniques for isolation of brush-border and basolateral membrane vesicles from dog kidney cortex.
Biochimica et biophysica acta 1989;983(1):77-81.
1989: Horacio J Adrogué; M N Rashad; A B Gorin; J Yacoub; Nicolaos E Madias
Assessing acid-base status in circulatory failure. Differences between arterial and central venous blood.
The New England journal of medicine 1989;320(20):1312-6.
1989: V J Canzanello; V G Millan; J E Spiegel; P S Ponce; R I Kopelman; Nicolaos E Madias
Percutaneous transluminal renal angioplasty in management of atherosclerotic renovascular hypertension: results in 100 patients.
Hypertension 1989;13(2):163-72.
1988: S A Hilden; C A Johns; Nicolaos E Madias
Cl(-)-dependent ATP-driven H+ transport in rabbit renal cortical endosomes.
The American journal of physiology 1988;255(5 Pt 2):F885-97.
1988: A S Levey; R D Perrone; Nicolaos E Madias
Serum creatinine and renal function.
Annual review of medicine 1988;39():465-90.
1987: V J Canzanello; Michael P. Madaio; Nicolaos E Madias
Enalapril in the management of hypertension associated with renal artery stenosis.
Journal of clinical pharmacology 1987;27(1):32-40.
1986: Horacio J Adrogué; Nicolaos E Madias
Renal acidification during chronic hypercapnia in the conscious dog.
Pflügers Archiv : European journal of physiology 1986;406(5):520-8.
1985: S A Bloom; V J Canzanello; J A Strom; Nicolaos E Madias
Spurious assessment of acid-base status due to dilutional effect of heparin.
The American journal of medicine 1985;79(4):528-30.
1985: V G Millan; J McCauley; R I Kopelman; Nicolaos E Madias
Percutaneous transluminal renal angioplasty in nonatherosclerotic renovascular hypertension. Long-term results.
Hypertension 1985;7(5):668-74.
1985: Horacio J Adrogué; Nicolaos E Madias
Influence of chronic respiratory acid-base disorders on acute CO2 titration curve.
Journal of applied physiology (Bethesda, Md. : 1985) 1985;58(4):1231-8.
1984: Nicolaos E Madias; S M Homer; C A Johns; J J Cohen
Hypochloremia as a consequence of anion gap metabolic acidosis.
The Journal of laboratory and clinical medicine 1984;104(1):15-23.
1984: Nicolaos E Madias; W H Bossert; Horacio J Adrogué
Ventilatory response to chronic metabolic acidosis and alkalosis in the dog.
Journal of applied physiology: respiratory, environmental and exercise physiology 1984;56(6):1640-6.
1983: Nicolaos E Madias; Horacio J Adrogué
Influence of chronic metabolic acid-base disorders on the acute CO2 titration curve.
Journal of applied physiology: respiratory, environmental and exercise physiology 1983;55(4):1187-95.
1983: Horacio J Adrogué; J Brensilver; J J Cohen; Nicolaos E Madias
Influence of steady-state alterations in acid-base equilibrium on the fate of administered bicarbonate in the dog.
The Journal of clinical investigation 1983;71(4):867-83.
1982: Nicolaos E Madias; C A Johns; S M Homer
Independence of the acute acid-buffering response from endogenous parathyroid hormone.
The American journal of physiology 1982;243(2):F141-9.
1982: Nicolaos E Madias; O J Kwon; V G Millan
Percutaneous transluminal renal angioplasty. A potentially effective treatment for preservation of renal function.
Archives of internal medicine 1982;142(4):693-7.
1981: Horacio J Adrogué; Nicolaos E Madias
Changes in plasma potassium concentration during acute acid-base disturbances.
The American journal of medicine 1981;71(3):456-67.
1981: Nicolaos E Madias; V G Millan
PTRA in the treatment of renovascular hypertension.
Hospital practice (Office ed.) 1981;16(8):105-16.
1981: Nicolaos E Madias; J T Ball; V G Millan
Percutaneous transluminal renal angioplasty in the treatment of unilateral atherosclerotic renovascular hypertension.
The American journal of medicine 1981;70(5):1078-84.
1980: Nicolaos E Madias; Horacio J Adrogué; J J Cohen
Maladaptive renal response to secondary hypercapnia in chronic metabolic alkalosis.
The American journal of physiology 1980;238(4):F283-9.