Sten Madsbad

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Nauck Michael A; Vilsbøll Tina; Gallwitz Baptist; Garber Alan; Madsbad Sten
Incretin-based therapies: viewpoints on the way to consensus.
Svendsen P F; Madsbad S; Nilas L; Paulsen S K; Pedersen S B
Expression of 11beta-hydroxysteroid dehydrogenase 1 and 2 in subcutaneous adipose tissue of lean and obese women with and without polycystic ovary syndrome.
Nielsen Anne-Louise Hother; Larsen Thomas Meinert; Madsbad Sten; Breum Leif; Jensen Thomas Jon; Kroustrup Jens Peter; Astrup Arne
[The effect of tesofensine on body weight and body composition in obese subjects--secondary publication]

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All Publications

2009: Nauck Michael A; Vilsbøll Tina; Gallwitz Baptist; Garber Alan; Madsbad Sten
Incretin-based therapies: viewpoints on the way to consensus.
Diabetes care 2009;32 Suppl 2():S223-31.
2009: Svendsen P F; Madsbad S; Nilas L; Paulsen S K; Pedersen S B
Expression of 11beta-hydroxysteroid dehydrogenase 1 and 2 in subcutaneous adipose tissue of lean and obese women with and without polycystic ovary syndrome.
International journal of obesity (2005) 2009;33(11):1249-56.
2009: Nielsen Anne-Louise Hother; Larsen Thomas Meinert; Madsbad Sten; Breum Leif; Jensen Thomas Jon; Kroustrup Jens Peter; Astrup Arne
[The effect of tesofensine on body weight and body composition in obese subjects--secondary publication]
Ugeskrift for laeger 2009;171(41):2974-7.
2009: Madsbad Sten
Exenatide and liraglutide: different approaches to develop GLP-1 receptor agonists (incretin mimetics)--preclinical and clinical results.
Best practice & research. Clinical endocrinology & metabolism 2009;23(4):463-77.
2009: Rabøl Rasmus; Svendsen Pernille F; Skovbro Mette; Boushel Robert; Haugaard Steen B; Schjerling Peter; Schrauwen Patrick; Hesselink Matthijs K C; Nilas Lisbeth; Madsbad Sten; Dela Flemming
Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss.
Metabolism: clinical and experimental 2009;58(8):1145-52.
2009: Haugaard Steen B; Mu Huiling; Vaag Allan; Madsbad Sten
Intramyocellular triglyceride content in man, influence of sex, obesity and glycaemic control.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161(1):57-64.
2009: Sparsø T; Grarup N; Andreasen C; Albrechtsen A; Holmkvist J; Andersen G; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Madsbad S; Hansen T; Pedersen O
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.
Diabetologia 2009;52(7):1308-14.
2009: Pilgaard K; Jensen C B; Schou J H; Lyssenko V; Wegner L; Brøns C; Vilsbøll T; Hansen T; Madsbad S; Holst J J; Vølund A; Poulsen P; Groop L; Pedersen O; Vaag A A
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.
Diabetologia 2009;52(7):1298-307.
2009: Sparsø Thomas; Bonnefond Amélie; Andersson Ehm; Bouatia-Naji Nabila; Holmkvist Johan; Wegner Lise; Grarup Niels; Gjesing Anette P; Banasik Karina; Cavalcanti-Proença Christine; Marchand Marion; Vaxillaire Martine; Charpentier Guillaume; Jarvelin Marjo-Riitta; Tichet Jean; Balkau Beverley; Marre Michel; Lévy-Marchal Claire; Faerch Kristine; Borch-Johnsen Knut; Jørgensen Torben; Madsbad Sten; Poulsen Pernille; Vaag Allan; Dina Christian; Hansen Torben; Pedersen Oluf; Froguel Philippe
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.
Diabetes 2009;58(6):1450-6.
2009: Svendsen Pernille Fog; Nilas Lisbeth; Madsbad Sten; Holst Jens Juul
Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin.
Metabolism: clinical and experimental 2009;58(5):586-93.
2009: Rabøl R; Højberg P M V; Almdal T; Boushel R; Haugaard S B; Madsbad S; Dela F
Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes.
Diabetes, obesity & metabolism 2009;11(4):355-60.
2009: Rabøl Rasmus; Højberg Patricia M V; Almdal Thomas; Boushel Robert; Haugaard Steen B; Madsbad Sten; Dela Flemming
Effect of hyperglycemia on mitochondrial respiration in type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2009;94(4):1372-8.
2009: Olesen Stine Chabert; Hansen Dorte Lindqvist; Almdal Thomas; Bendtsen Flemming; Nordgaard Inge; Hvolris Lisbeth Edvardsen; Holst Jens J; Naver Lars; Madsbad Sten
[Surgical treatment of diabetes mellitus type 2]
Ugeskrift for laeger 2009;171(8):615-7.
2009: Aaboe Kasper; Knop Filip Krag; Vilsboll Tina; Vølund Aage; Simonsen Ulf; Deacon Carolyn Fiona; Madsbad Sten; Holst Jens Juul; Krarup Thure
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2009;94(2):603-8.
2009: Højberg P V; Vilsbøll T; Rabøl R; Knop F K; Bache M; Krarup T; Holst J J; Madsbad S
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.
Diabetologia 2009;52(2):199-207.
2009: Madsbad Sten
Treatment of type 2 diabetes with incretin-based therapies.
Lancet 2009;373(9662):438-9.
2009: Haugaard Steen B; Vaag Allan; Mu Huiling; Madsbad Sten
Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention.
Lipids in health and disease 2009;8():34.
2008: Højberg P V; Vilsbøll T; Zander M; Knop F K; Krarup T; Vølund A; Holst J J; Madsbad S
Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2008;25(11):1268-75.
2008: Madsbad Sten
[Glycemic control and cardiovascular diseases in type 2 diabetes]
Ugeskrift for laeger 2008;170(45):3634.
2008: Astrup Arne; Madsbad Sten; Breum Leif; Jensen Thomas J; Kroustrup Jens Peter; Larsen Thomas Meinert
Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial.
Lancet 2008;372(9653):1906-13.
2008: Aaboe Kasper; Krarup Thure; Madsbad Sten; Holst Jens Juul
GLP-1: physiological effects and potential therapeutic applications.
Diabetes, obesity & metabolism 2008;10(11):994-1003.
2008: Jeppesen Jørgen; Hansen Tine W; Olsen Michael H; Rasmussen Susanne; Ibsen Hans; Torp-Pedersen Christian; Hildebrandt Per R; Madsbad Sten
C-reactive protein, insulin resistance and risk of cardiovascular disease: a population-based study.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2008;15(5):594-8.
2008: Sparsø T; Andersen G; Albrechtsen A; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Wasson J; Permutt M A; Glaser B; Madsbad S; Pedersen O; Hansen T
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.
Diabetologia 2008;51(9):1646-52.
2008: Svendsen Pernille Fog; Nilas Lisbeth; Nørgaard Kirsten; Jensen Jens-Erik Beck; Madsbad Sten
Obesity, body composition and metabolic disturbances in polycystic ovary syndrome.
Human reproduction (Oxford, England) 2008;23(9):2113-21.
2008: Madsbad Sten; Krarup Thure; Deacon Carolyn F; Holst Jens J
Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials.
Current opinion in clinical nutrition and metabolic care 2008;11(4):491-9.
2008: Skov Lone; Hegedüs Laszlo; Madsbad Sten; Bendtzen Klaus
[New biological drugs for the treatment of chronic inflammatory diseases]
Ugeskrift for laeger 2008;170(24):2162.
2008: Holst Jens J; Deacon Carolyn F; Vilsbøll Tina; Krarup Thure; Madsbad Sten
Glucagon-like peptide-1, glucose homeostasis and diabetes.
Trends in molecular medicine 2008;14(4):161-8.
2008: Højberg P V; Zander M; Vilsbøll T; Knop F K; Krarup T; Vølund A; Holst J J; Madsbad S
Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes.
Diabetologia 2008;51(4):632-40.
2008: Vilsbøll T; Brock B; Perrild H; Levin K; Lervang H-H; Kølendorf K; Krarup T; Schmitz O; Zdravkovic M; Le-Thi T; Madsbad S
Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 2008;25(2):152-6.
2008: Sparsø T; Andersen G; Nielsen T; Burgdorf K S; Gjesing A P; Nielsen A L; Albrechtsen A; Rasmussen S S; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Madsbad S; Hansen T; Pedersen O
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.
Diabetologia 2008;51(1):70-5.
2008: Jensen Christine B; Martin-Gronert Malgorzata S; Storgaard Heidi; Madsbad Sten; Vaag Allan; Ozanne Susan E
Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight.
PloS one 2008;3(11):e3738.
2007: Knop Filip K; Vilsbøll Tina; Højberg Patricia V; Larsen Steen; Madsbad Sten; Holst Jens J; Krarup Thure
The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.
Regulatory peptides 2007;144(1-3):123-30.
2007: Madsbad Sten
[Treatment of patients with type 2 diabetes mellitus with pioglitazone. A survey of a Cochrane review]
Ugeskrift for laeger 2007;169(47):4054-7.
2007: Sparsø Thomas; Hussain Meena Shaheen; Borch-Johnsen Knut; Jørgensen Torben; Madsbad Sten; Hansen Torben; Pedersen Oluf; Andersen Gitte
Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites.
Molecular genetics and metabolism 2007;92(3):278-82.
2007: Andersen Ove; Pedersen Steen B; Svenstrup Birgit; Hansen Birgitte R; Paulsen Søren K; Rathje Gulla S; Richelsen Bjørn; Nielsen Jens Ole; Madsbad Sten; Iversen Johan; Haugaard Steen B
Circulating sex hormones and gene expression of subcutaneous adipose tissue oestrogen and alpha-adrenergic receptors in HIV-lipodystrophy: implications for fat distribution.
Clinical endocrinology 2007;67(2):250-8.
2007: Knop Filip K; Vilsbøll Tina; Højberg Patricia V; Larsen Steen; Madsbad Sten; Vølund Aage; Holst Jens J; Krarup Thure
Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?
Diabetes 2007;56(8):1951-9.
2007: Haugaard Steen B; Andersen Ove; Halsall Ian; Iversen Johan; Hales Charles Nicholas; Madsbad Stein
Impaired proinsulin secretion before and during oral glucose stimulation in HIV-infected patients who display fat redistribution.
Metabolism: clinical and experimental 2007;56(7):939-46.
2007: Vilsbøll Tina; Zdravkovic Milan; Le-Thi Tu; Krarup Thure; Schmitz Ole; Courrèges Jean-Pierre; Verhoeven Robert; Bugánová Ingrid; Madsbad Sten
Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes.
Diabetes care 2007;30(6):1608-10.
2007: Jeppesen Jørgen; Hansen Tine W; Rasmussen Susanne; Ibsen Hans; Torp-Pedersen Christian; Madsbad Sten
Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease: a population-based study.
Journal of the American College of Cardiology 2007;49(21):2112-9.
2007: Jensen Christine B; Storgaard Heidi; Madsbad Sten; Richter Erik A; Vaag Allan A
Altered skeletal muscle fiber composition and size precede whole-body insulin resistance in young men with low birth weight.
The Journal of clinical endocrinology and metabolism 2007;92(4):1530-4.
2007: Knop F K; Vilsbøll T; Madsbad S; Holst J J; Krarup T
Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus.
Diabetologia 2007;50(4):797-805.
2007: Haugaard Steen B; Vaag Allan; Høy Carl-Erik; Madsbad Sten
Desaturation of skeletal muscle structural and depot lipids in obese individuals during a very-low-calorie diet intervention.
Obesity (Silver Spring, Md.) 2007;15(1):117-25.
2007: Richelsen Bjørn; Tonstad Serena; Rössner Stephan; Toubro Søren; Niskanen Leo; Madsbad Steen; Mustajoki Pertti; Rissanen Aila
Effect of orlistat on weight regain and cardiovascular risk factors following a very-low-energy diet in abdominally obese patients: a 3-year randomized, placebo-controlled study.
Diabetes care 2007;30(1):27-32.
2007: Knop Filip K; Vilsbøll Tina; Larsen Steen; Højberg Patricia V; Vølund Aage; Madsbad Sten; Holst Jens J; Krarup Thure
Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution.
American journal of physiology. Endocrinology and metabolism 2007;292(1):E324-30.
2007: Haugaard Steen B; Andersen Ove; Madsbad Sten; Iversen Johan; Dela Flemming
Glucose production, oxidation and disposal correlate with plasma lactate levels in HIV-infected patients on HAART.
The Journal of infection 2007;54(1):89-97.
2006: Vilsbøll Tina; Agersø Henrik; Lauritsen Torsten; Deacon Carolyn F; Aaboe Kasper; Madsbad Sten; Krarup Thure; Holst Jens Juul
The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.
Regulatory peptides 2006;137(3):168-72.
2006: Ryskjaer Jakob; Deacon Carolyn F; Carr Richard D; Krarup Thure; Madsbad Sten; Holst Jens; Vilsbøll Tina
Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake.
European journal of endocrinology / European Federation of Endocrine Societies 2006;155(3):485-93.
2006: Haugaard S B; Andersen O; Hales C N; Halsall I; Rosenfalck A M; Iversen J; Madsbad S
Hyperproinsulinaemia in normoglycaemic lipodystrophic HIV-infected patients.
European journal of clinical investigation 2006;36(6):436-45.
2006: Haugaard Steen B; Andersen Ove; Flyvbjerg Allan; Ørskov Hans; Madsbad Sten; Iversen Johan
Growth factors, glucose and insulin kinetics after low dose growth hormone therapy in HIV-lipodystrophy.
The Journal of infection 2006;52(6):389-98.
2006: Schmitz Ole E; Brock Birgitte; Rungby Jørgen; Madsbad Sten
[The place of Glitazones in the treatment of diabetes: after the PROactive study]
Ugeskrift for laeger 2006;168(18):1750-2.
2006: Madsbad Sten; Larsen Mogens Lytken; Adeler Haagen F; Kryhlmand Marianne; Westergaard Mogens
[Implementation of clinical guidelines in general practice. The effect of journal audit and continuing education for the treatment of cardiovascular risk factors in patients with and without type 2 diabetes]
Ugeskrift for laeger 2006;168(17):1640-5.
2006: Rosenfalck A M; Almdal T; Viggers L; Madsbad S; Hilsted J
A low-fat diet improves peripheral insulin sensitivity in patients with Type 1 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2006;23(4):384-92.
2006: Haugaard S B; Andersen O; Pedersen S B; Dela F; Deacon C F; Holst J J; Iversen J; Madsbad S
Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagon, lactate and TNF-alpha in patients with HIV-lipodystrophy.
HIV medicine 2006;7(3):163-72.
2006: Bouzakri Karim; Karlsson Håkan K R; Vestergaard Henrik; Madsbad Sten; Christiansen Erik; Zierath Juleen R
IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients.
Diabetes 2006;55(3):785-91.
2006: Haugaard Steen B; Madsbad Sten; Høy Carl-Erik; Vaag Allan
Dietary intervention increases n-3 long-chain polyunsaturated fatty acids in skeletal muscle membrane phospholipids of obese subjects. Implications for insulin sensitivity.
Clinical endocrinology 2006;64(2):169-78.
2006: Haugaard Steen B; Andersen Ove; Pedersen Steen B; Dela Flemming; Fenger Mogens; Richelsen Bjørn; Madsbad Sten; Iversen Johan
Tumor necrosis factor alpha is associated with insulin-mediated suppression of free fatty acids and net lipid oxidation in HIV-infected patients with lipodystrophy.
Metabolism: clinical and experimental 2006;55(2):175-82.
2006: Zander M; Madsbad S; Deacon C F; Holst J J
The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes.
Diabetologia 2006;49(2):369-74.
2006: Madsbad Sten; Richelsen Bjørn
[Weight loss treatment of obese type 2 diabetic patients]
Ugeskrift for laeger 2006;168(2):175-9.
2006: Berentzen Tina; Madsbad Sten; Sørensen Thorkild I A; Astrup Arne V
[The importance of physical activity and fitness in avoiding the complications of obesity]
Ugeskrift for laeger 2006;168(2):144-9.
2005: Haugaard Steen B; Andersen Ove; Madsbad Sten; Frøsig Christian; Iversen Johan; Nielsen Jens Ole; Wojtaszewski Jørgen F P
Skeletal muscle insulin signaling defects downstream of phosphatidylinositol 3-kinase at the level of Akt are associated with impaired nonoxidative glucose disposal in HIV lipodystrophy.
Diabetes 2005;54(12):3474-83.
2005: Carlsson Emma; Poulsen Pernille; Storgaard Heidi; Almgren Peter; Ling Charlotte; Jensen Christine Bjørn; Madsbad Sten; Groop Leif; Vaag Allan; Ridderstråle Martin
Genetic and nongenetic regulation of CAPN10 mRNA expression in skeletal muscle.
Diabetes 2005;54(10):3015-20.
2005: Jensen Christine B; Storgaard Heidi; Holst Jens Juul; Dela Flemming; Madsbad Sten; Vaag Allan
Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls.
Metabolism: clinical and experimental 2005;54(10):1398-406.
2005: He G; Andersen O; Haugaard S B; Lihn A S; Pedersen S B; Madsbad S; Richelsen B
Plasminogen activator inhibitor type 1 (PAI-1) in plasma and adipose tissue in HIV-associated lipodystrophy syndrome. Implications of adipokines.
European journal of clinical investigation 2005;35(9):583-90.
2005: Bing C; Ambye L; Fenger M; Jørgensen T; Borch-Johnsen K; Madsbad S; Urhammer S A
Large-scale studies of the Leu72Met polymorphism of the ghrelin gene in relation to the metabolic syndrome and associated quantitative traits.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(9):1157-60.
2005: Haugaard Steen B; Andersen Ove; Pedersen Steen B; Dela Flemming; Richelsen Bjørn; Nielsen Jens Ole; Madsbad Sten; Iversen Johan
Depleted skeletal muscle mitochondrial DNA, hyperlactatemia, and decreased oxidative capacity in HIV-infected patients on highly active antiretroviral therapy.
Journal of medical virology 2005;77(1):29-38.
2005: Svendsen Pernille Fog; Nilas Lisbeth; Nørgaard Kirsten; Madsbad Sten
[Polycystic ovary syndrome. New pathophysiological discoveries--therapeutic consequences]
Ugeskrift for laeger 2005;167(34):3147-51.
2005: Schou Jakob Hagen; Pilgaard Kasper; Vilsbøll Tina; Jensen Christine B; Deacon Carolyn F; Holst Jens Juul; Vølund Aage; Madsbad Sten; Vaag Allan A
Normal secretion and action of the gut incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in young men with low birth weight.
The Journal of clinical endocrinology and metabolism 2005;90(8):4912-9.
2005: Andersen O; Haugaard S B; Holst J J; Deacon C F; Iversen J; Andersen U B; Nielsen J O; Madsbad S
Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy.
HIV medicine 2005;6(2):91-8.
2005: Haugaard Steen B; Andersen Ove; Vølund Aage; Hansen Birgitte R; Iversen Johan; Andersen Ulrik B; Nielsen Jens Ole; Madsbad Sten
Beta-cell dysfunction and low insulin clearance in insulin-resistant human immunodeficiency virus (HIV)-infected patients with lipodystrophy.
Clinical endocrinology 2005;62(3):354-61.
2005: Ozanne S E; Jensen C B; Tingey K J; Storgaard H; Madsbad S; Vaag A A
Low birthweight is associated with specific changes in muscle insulin-signalling protein expression.
Diabetologia 2005;48(3):547-52.
2005: Haugaard Steen B; Andersen Ove; Hansen Birgitte R; Andersen Ulrik B; Vølund Aage; Iversen Johan; Nielsen Jens Ole; Madsbad Sten
In nondiabetic, human immunodeficiency virus-infected patients with lipodystrophy, hepatic insulin extraction and posthepatic insulin clearance rate are decreased in proportion to insulin resistance.
Metabolism: clinical and experimental 2005;54(2):171-9.
2005: Ambye Louise; Rasmussen Susanne; Fenger Mogens; Jørgensen Torben; Borch-Johnsen Knut; Madsbad Sten; Urhammer Søren A
Studies of the Gly482Ser polymorphism of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) gene in Danish subjects with the metabolic syndrome.
Diabetes research and clinical practice 2005;67(2):175-9.
2005: Haugaard Steen B; Andersen Ove; Dela Flemming; Holst Jens Juul; Storgaard Heidi; Fenger Mogens; Iversen Johan; Madsbad Sten
Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.
European journal of endocrinology / European Federation of Endocrine Societies 2005;152(1):103-12.
2005: Rasmussen Eva Lind; Malis Charlotte; Jensen Christine Bjørn; Jensen Jens-Erik Beck; Storgaard Heidi; Poulsen Pernille; Pilgaard Kasper; Schou Jacob Hagen; Madsbad Sten; Astrup Arne; Vaag Allan
Altered fat tissue distribution in young adult men who had low birth weight.
Diabetes care 2005;28(1):151-3.
2004: Haugaard Steen B; Andersen Ove; Hansen Birgitte R; Orskov Hans; Andersen Ulrik B; Madsbad Sten; Iversen Johan; Flyvbjerg Allan
Insulin-like growth factors, insulin-like growth factor-binding proteins, insulin-like growth factor-binding protein-3 protease, and growth hormone-binding protein in lipodystrophic human immunodeficiency virus-infected patients.
Metabolism: clinical and experimental 2004;53(12):1565-73.
2004: Barnett Anthony H; Bain Stephen C; Bouter Paul; Karlberg Bengt; Madsbad Sten; Jervell Jak; Mustonen Jukka;
Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy.
The New England journal of medicine 2004;351(19):1952-61.
2004: Haugaard Steen B; Andersen Ove; Storgaard Heidi; Dela Flemming; Holst Jens Juul; Iversen Johan; Nielsen Jens Ole; Madsbad Sten
Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.
American journal of physiology. Endocrinology and metabolism 2004;287(4):E677-85.
2004: Andersen O; Haugaard S B; Flyvbjerg A; Andersen U B; Ørskov H; Madsbad S; Nielsen J O; Iversen J
Low-dose growth hormone and human immunodeficiency virus-associated lipodystrophy syndrome: a pilot study.
European journal of clinical investigation 2004;34(8):561-8.
2004: Zander Mette; Christiansen Allan; Madsbad Sten; Holst Jens Juul
Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes.
Diabetes care 2004;27(8):1910-4.
2004: Madsbad Sten; Schmitz Ole; Ranstam Jonas; Jakobsen Grethe; Matthews David R;
Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial.
Diabetes care 2004;27(6):1335-42.
2004: Madsbad Sten; Astrup Arne V
[Obesity, the metabolic syndrome and cardiovascular disease]
Ugeskrift for laeger 2004;166(17):1561-4.
2004: Storgaard Heidi; Jensen Christine B; Björnholm Marie; Song Xiao Mei; Madsbad Sten; Zierath Juleen R; Vaag Allan A
Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2004;89(3):1301-11.
2004: Andersen Ove; Haugaard Steen B; Hansen Birgitte R; Orskov Hans; Andersen Ulrik B; Madsbad Sten; Iversen Johan; Flyvbjerg Allan
Different growth hormone sensitivity of target tissues and growth hormone response to glucose in HIV-infected patients with and without lipodystrophy.
Scandinavian journal of infectious diseases 2004;36(11-12):832-9.
2003: Lihn Aina S; Richelsen Bjørn; Pedersen Steen B; Haugaard Steen B; Rathje Gulla Søby; Madsbad Sten; Andersen Ove
Increased expression of TNF-alpha, IL-6, and IL-8 in HALS: implications for reduced adiponectin expression and plasma levels.
American journal of physiology. Endocrinology and metabolism 2003;285(5):E1072-80.
2003: Hansen Birgitte Rønde; Haugaard Steen B; Nielsen Jens Ole; Madsbad Sten; Iversen Johan; Andersen Ove
[Control and treatment of HIV-associated lipodystrophy syndrome and related metabolic complications]
Ugeskrift for laeger 2003;165(44):4218-20.
2003: Haugaard Steen B; Hansen Birgitte Rønde; Madsbad Sten; Iversen Johan; Nielsen Jens Ole; Andersen Ove
[HIV-associated lipodystrophy syndrome. Diagnosis, prevalence, pathogenesis and metabolic complications]
Ugeskrift for laeger 2003;165(44):4215-8.
2003: Andersen Ove; Haugaard Steen B; Andersen Ulrik B; Friis-Møller Nina; Storgaard Heidi; Vølund Aage; Nielsen Jens Ole; Iversen Johan; Madsbad Sten
Lipodystrophy in human immunodeficiency virus patients impairs insulin action and induces defects in beta-cell function.
Metabolism: clinical and experimental 2003;52(10):1343-53.
2003: Vilsbøll T; Knop F K; Krarup T; Johansen A; Madsbad S; Larsen S; Hansen T; Pedersen O; Holst J J
The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype.
The Journal of clinical endocrinology and metabolism 2003;88(10):4897-903.
2003: Knop Filip K; Vilsbøll Tina; Larsen Steen; Madsbad Sten; Holst Jens J; Krarup Thure
No hypoglycemia after subcutaneous administration of glucagon-like peptide-1 in lean type 2 diabetic patients and in patients with diabetes secondary to chronic pancreatitis.
Diabetes care 2003;26(9):2581-7.
2003: Madsbad Sten; Brock Birgitte; Schmitz Ole
[Postprandial hyperglycemia. Postprandial blood glucose fluctuations, cardiovascular disease and late diabetic complications]
Ugeskrift for laeger 2003;165(33):3149-53.
2003: Storgaard Heidi; Jensen Christine B; Vaag Allan A; Vølund Aage; Madsbad Sten
Insulin secretion after short- and long-term low-grade free fatty acid infusion in men with increased risk of developing type 2 diabetes.
Metabolism: clinical and experimental 2003;52(7):885-94.
2003: Vilsbøll Tina; Krarup Thure; Madsbad Sten; Holst Jens J
Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects.
Regulatory peptides 2003;114(2-3):115-21.
2003: Jensen Christine B; Storgaard Heidi; Holst Jens J; Dela Flemming; Madsbad Sten; Vaag Allan A
Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men.
The Journal of clinical endocrinology and metabolism 2003;88(6):2775-83.
2003: Vilsbøll T; Krarup T; Sonne J; Madsbad S; Vølund A; Juul A G; Holst J J
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 2003;88(6):2706-13.
2003: Frederiksen L; Brødbaek K; Fenger M; Madsbad S; Urhammer S A; Jørgensen T; Borch-Johnsen K
No interactions between polymorphisms in the beta3-adrenergic receptor gene and the PPAR-gamma gene on the risk of the insulin resistance syndrome in the Danish MONICA cohort.
Diabetologia 2003;46(5):729-31.
2003: Kjems Lise L; Holst Jens J; Vølund Aage; Madsbad Sten
The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects.
Diabetes 2003;52(2):380-6.
2003: Andersen O; Haugaard S B; Jørgensen L T; Sørensen S; Nielsen J O; Madsbad S; Iversen J
Preanalytical handling of samples for measurement of plasma lactate in HIV patients.
Scandinavian journal of clinical and laboratory investigation 2003;63(6):449-54.
2002: Andersson Kerstin; Buschard Karsten; Fredman Pam; Kaas Anne; Lidström Anna-Maria; Madsbad Sten; Mortensen Henrik; Jan-Eric Månsson
Patients with insulin-dependent diabetes but not those with non-insulin-dependent diabetes have anti-sulfatide antibodies as determined with a new ELISA assay.
Autoimmunity 2002;35(7):463-8.
2002: Vilsbøll T; Krarup T; Madsbad S; Holst J J
Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients.
Diabetologia 2002;45(8):1111-9.
2002: Frederiksen Laura; Brødbaek Kasper; Fenger Mogens; Jørgensen Torben; Borch-Johnsen Knut; Madsbad Sten; Urhammer Søren A
Comment: studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome.
The Journal of clinical endocrinology and metabolism 2002;87(8):3989-92.
2002: Buschard Karsten; Høy Marianne; Bokvist Krister; Olsen Hervør L; Madsbad Sten; Fredman Pam; Gromada Jesper
Sulfatide controls insulin secretion by modulation of ATP-sensitive K(+)-channel activity and Ca(2+)-dependent exocytosis in rat pancreatic beta-cells.
Diabetes 2002;51(8):2514-21.
2002: Hermansen Kjeld; Vaaler Stein; Madsbad Sten; Dalgaard Marian; Zander Mette; Begtrup Kamilla; Soendergaard Karsten
Postprandial glycemic control with biphasic insulin aspart in patients with type 1 diabetes.
Metabolism: clinical and experimental 2002;51(7):896-900.
2002: Rosenfalck A M; Almdal T; Hilsted J; Madsbad S
Body composition in adults with Type 1 diabetes at onset and during the first year of insulin therapy.
Diabetic medicine : a journal of the British Diabetic Association 2002;19(5):417-23.
2002: Hermansen Kjeld; Colombo Michele; Storgaard Heidi; ØStergaard Anette; Kølendorf Klaus; Madsbad Sten
Improved postprandial glycemic control with biphasic insulin aspart relative to biphasic insulin lispro and biphasic human insulin in patients with type 2 diabetes.
Diabetes care 2002;25(5):883-8.
2002: Christiansen Allan Lindskov; Madsbad Sten
[Metformin. Mode of action and effect of monotherapy and combination therapy on glucose metabolism in type 2 diabetes]
Ugeskrift for laeger 2002;164(15):2025-8.
2002: Christiansen Allan Lindskov; Madsbad Sten
[The effect of metformin on late diabetic complications and cardiovascular events in obese patients with type 2 diabetes]
Ugeskrift for laeger 2002;164(15):2022-4.
2002: Jensen Christine B; Storgaard Heidi; Dela Flemming; Holst Jens Juul; Madsbad Sten; Vaag Allan A
Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight.
Diabetes 2002;51(4):1271-80.
2002: Zander Mette; Madsbad Sten; Madsen Jan Lysgaard; Holst Jens Juul
Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study.
Lancet 2002;359(9309):824-30.
2002: Madsbad Sten
Insulin analogues: have they changed insulin treatment and improved glycaemic control?
Diabetes/metabolism research and reviews 2002;18 Suppl 1():S21-8.
2002: Rosenfalck A M; Hendel H; Rasmussen M H; Almdal T; Anderson T; Hilsted J; Madsbad S
Minor long-term changes in weight have beneficial effects on insulin sensitivity and beta-cell function in obese subjects.
Diabetes, obesity & metabolism 2002;4(1):19-28.
2001: Storgaard H; Song X M; Jensen C B; Madsbad S; Björnholm M; Vaag A; Zierath J R
Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].
Diabetes 2001;50(12):2770-8.
2001: Schmitz O E; Brock B; Madsbad S; Beck-Nielsen H
[Thiazolidinediones--a new class of oral antidiabetics]
Ugeskrift for laeger 2001;163(44):6106-11.
2001: Kjems L L; Vølund A; Madsbad S
Quantification of beta-cell function during IVGTT in Type II and non-diabetic subjects: assessment of insulin secretion by mathematical methods.
Diabetologia 2001;44(10):1339-48.
2001: Toft-Nielsen M B; Madsbad S; Holst J J
Determinants of the effectiveness of glucagon-like peptide-1 in type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2001;86(8):3853-60.
2001: Toft-Nielsen M B; Damholt M B; Madsbad S; Hilsted L M; Hughes T E; Michelsen B K; Holst J J
Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients.
The Journal of clinical endocrinology and metabolism 2001;86(8):3717-23.
2001: Madsbad S; Kilhovd B; Lager I; Mustajoki P; Dejgaard A;
Comparison between repaglinide and glipizide in Type 2 diabetes mellitus: a 1-year multicentre study.
Diabetic medicine : a journal of the British Diabetic Association 2001;18(5):395-401.
2001: Zander M; Taskiran M; Toft-Nielsen M B; Madsbad S; Holst J J
Additive glucose-lowering effects of glucagon-like peptide-1 and metformin in type 2 diabetes.
Diabetes care 2001;24(4):720-5.
2001: Vilsbøll T; Krarup T; Deacon C F; Madsbad S; Holst J J
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.
Diabetes 2001;50(3):609-13.
2001: Vilsbøll T; Krarup T; Madsbad S; Holst J J
No reactive hypoglycaemia in Type 2 diabetic patients after subcutaneous administration of GLP-1 and intravenous glucose.
Diabetic medicine : a journal of the British Diabetic Association 2001;18(2):144-9.
2001: Hermansen K; Madsbad S; Perrild H; Kristensen A; Axelsen M
Comparison of the soluble basal insulin analog insulin detemir with NPH insulin: a randomized open crossover trial in type 1 diabetic subjects on basal-bolus therapy.
Diabetes care 2001;24(2):296-301.
2001: Christiansen A L; Madsbad S
[Jet leg]
Ugeskrift for laeger 2001;163(2):149-55.
2000: Rosenfalck A M; Maghsoudi S; Fisker S; Jørgensen J O; Christiansen J S; Hilsted J; Vølund A A; Madsbad S
The effect of 30 months of low-dose replacement therapy with recombinant human growth hormone (rhGH) on insulin and C-peptide kinetics, insulin secretion, insulin sensitivity, glucose effectiveness, and body composition in GH-deficient adults.
The Journal of clinical endocrinology and metabolism 2000;85(11):4173-81.
2000: Jørgensen J O; Rosenfalck A M; Fisker S; Nyholm B; Fineman M S; Schmitz O; Madsbad S; Holst J J; Christiansen J S
Circulating levels of incretin hormones and amylin in the fasting state and after oral glucose in GH-deficient patients before and after GH replacement: a placebo-controlled study.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(5):593-9.
2000: Vilsbøll T; Toft-Nielsen M B; Krarup T; Madsbad S; Dinesen B; Holst J J
Evaluation of beta-cell secretory capacity using glucagon-like peptide 1.
Diabetes care 2000;23(6):807-12.
2000: Kjems L L; Christiansen E; Vølund A; Bergman R N; Madsbad S
Validation of methods for measurement of insulin secretion in humans in vivo.
Diabetes 2000;49(4):580-8.
2000: Rosenfalck A M; Thorsby P; Kjems L; Birkeland K; Dejgaard A; Hanssen K F; Madsbad S
Improved postprandial glycaemic control with insulin Aspart in type 2 diabetic patients treated with insulin.
Acta diabetologica 2000;37(1):41-6.
1999: Larsen J J; Dela F; Madsbad S; Galbo H
The effect of intense exercise on postprandial glucose homeostasis in type II diabetic patients.
Diabetologia 1999;42(11):1282-92.
1999: Larsen J J; Dela F; Madsbad S; Vibe-Petersen J; Galbo H
Interaction of sulfonylureas and exercise on glucose homeostasis in type 2 diabetic patients.
Diabetes care 1999;22(10):1647-54.
1999: Toft-Nielsen M B; Madsbad S; Holst J J
Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients.
Diabetes care 1999;22(7):1137-43.
1999: Rosenfalck A M; Fisker S; Hilsted J; Dinesen B; Vølund A; Jørgensen J O; Christiansen J S; Madsbad S
The effect of the deterioration of insulin sensitivity on beta-cell function in growth-hormone-deficient adults following 4-month growth hormone replacement therapy.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1999;9(2):96-105.
1998: Toft-Nielsen M; Madsbad S; Holst J J
Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia.
Diabetologia 1998;41(10):1180-6.
1998: Christiansen E; Røder M; Tibell A; Hales C N; Madsbad S
Effect of pancreas transplantation and immunosuppression on proinsulin secretion.
Diabetic medicine : a journal of the British Diabetic Association 1998;15(9):739-46.
1998: Christiansen E; Kjems L L; Vølund A; Tibell A; Binder C; Madsbad S
Insulin secretion rates estimated by two mathematical methods in pancreas-kidney transplant recipients.
The American journal of physiology 1998;274(4 Pt 1):E716-25.
1997: Christiansen E; Tibell A; Vølund A A; Holst J J; Rasmussen K; Schäffer L; Madsbad S
Metabolism of oral glucose in pancreas transplant recipients with normal and impaired glucose tolerance.
The Journal of clinical endocrinology and metabolism 1997;82(7):2299-307.
1996: Christiansen E; Tibell A; Vølund A; Rasmussen K; Groth C G; Holst J J; Pedersen O; Christensen N J; Madsbad S
Pancreatic endocrine function in recipients of segmental and whole pancreas transplantation.
The Journal of clinical endocrinology and metabolism 1996;81(11):3972-9.
1996: Hilsted J C; Madsbad S; Rasmussen M H; Hvidberg A; Krarup T; Ipsen H; Hansen B; Pedersen M; Djurup R; Oxenbøll B
[Clinical consequences of intranasal insulin therapy in insulin-dependent diabetes mellitus]
Ugeskrift for laeger 1996;158(24):3451-5.
1996: Toft-Nielson M; Madsbad S; Holst J J
The effect of glucagon-like peptide I (GLP-I) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones.
Diabetes 1996;45(5):552-6.
1996: Frandsen H A; Snitker S; Christensen N J; Madsbad S
No differential effects of porcine and human insulin on muscle sympathetic nerve activity during euglycaemia or hypoglycaemia.
Clinical physiology (Oxford, England) 1996;16(1):9-21.
1996: Bech K; Damsbo P; Eldrup E; Beck-Nielsen H; Røder M E; Hartling S G; Vølund A; Madsbad S
beta-cell function and glucose and lipid oxidation in Graves' disease.
Clinical endocrinology 1996;44(1):59-66.
1995: Hilsted J; Madsbad S; Hvidberg A; Rasmussen M H; Krarup T; Ipsen H; Hansen B; Pedersen M; Djurup R; Oxenbøll B
Intranasal insulin therapy: the clinical realities.
Diabetologia 1995;38(6):680-4.
1995: Andersen H B; Christiansen E; Vølund A; Madsbad S; Rasmussen K; Burcharth F; Christensen N J
Sham feeding increases glucose tolerance by a mechanism independent of insulin secretion in normal subjects.
Digestion 1995;56(3):253-8.
1994: Madsbad S; Christiansen E; Tibell A; Tydén G; Rasmussen K; Burcharth F
Beta-cell dysfunction following successful segmental pancreas transplantation. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation.
Transplantation proceedings 1994;26(2):469-70.
1994: Christiansen E; Tibell A; Groth C G; Rasmussen K; Pedersen O; Burcharth F; Christensen N J; Vølund A; Madsbad S
Limitations in the use of insulin or C-peptide alone in the assessment of beta-cell function in pancreas transplant recipients. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation.
Transplantation proceedings 1994;26(2):467-8.
1993: Holst J J; Bersani M; Hvidberg A; Knigge U; Christiansen E; Madsbad S; Harling H; Kofod H
On the effects of human galanin in man.
Diabetologia 1993;36(7):653-7.
1993: Christiansen E; Tibell A; Rasmussen K; Tydén G; Madsbad S
Defects in quantitative and qualitative beta-cell function following successful segmental pancreas transplantation. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation (DSSGMEPT).
Transplantation proceedings 1993;25(1 Pt 2):1186-9.
1992: Andersen H B; Jensen E W; Madsbad S; Nielsen S L; Burcharth F; Christensen N J
Sham-feeding decreases cardiac output in normal subjects.
Clinical physiology (Oxford, England) 1992;12(4):439-42.
1992: Grønlund B; Grønlund L; Madsbad S; Fogh-Andersen N
Clinical evaluation of a prototype glucose electrode.
Biosensors & bioelectronics 1992;7(10):683-7.
1991: Saelsen L; Tronier B; Madsbad S; Christensen N J
A rapid method for determination of human C-peptide in plasma.
Clinica chimica acta; international journal of clinical chemistry 1991;196(1):1-6.
1991: Grønlund B; Frandsen H; Lauritzen M; Nielsen S L; Madsbad S
Effect of insulin-induced hypoglycaemia on absorption of unmodified insulin after subcutaneous or intramuscular injection.
Diabetic medicine : a journal of the British Diabetic Association 1991;8(1):13-7.

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