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Kiran Madura

Research Profile

Chemicals & Drugs

Living Beings

Saccharomyces cerevisiae

Physiology

Phenomena

Concepts & Ideas

Protein Structure, Tertiary

Genes & Molecular Sequences

Genes, Fungal

Co-author Network

Publications

TOP 3
MOHIT R JAIN; Amit Ketkar; Stella Elkabes; Qing Li; Tong Liu; Kiran Madura; Joseph Rinaggio; Vincent Tournier; Hong Li
Proteomic identification of immunoproteasome accumulation in formalin-fixed rodent spinal cords with experimental autoimmune encephalomyelitis.
Abhishek Chandra; Li Chen; Kiran Madura
Synthetic lethality of rpn11-1 rpn10Δ is linked to altered proteasome assembly and activity.
Kiran Madura
Cell biology: The proteasome assembly line.

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All Publications

2012: MOHIT R JAIN; Amit Ketkar; Stella Elkabes; Qing Li; Tong Liu; Kiran Madura; Joseph Rinaggio; Vincent Tournier; Hong Li
Proteomic identification of immunoproteasome accumulation in formalin-fixed rodent spinal cords with experimental autoimmune encephalomyelitis.
Journal of proteome research 2012;11(3):1791-803.
2010: Abhishek Chandra; Li Chen; Kiran Madura
Synthetic lethality of rpn11-1 rpn10Δ is linked to altered proteasome assembly and activity.
Current genetics 2010;56(6):543-57.
2009: Kiran Madura
Cell biology: The proteasome assembly line.
Nature 2009;459(7248):787-8.
2008: Nadia Hedhli; Paulo Lizano; Chull Hong; Luke F Fritzky; Sunil K Dhar; Huasheng Liu; Yimin Tian; Shumin Gao; Kiran Madura; Stephen F Vatner; Christophe Depre
Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload.
American journal of physiology. Heart and circulatory physiology 2008;295(4):H1385-93.
2008: Thangiah Geetha; M Lamar Seibenhener; Li Chen; Kiran Madura; Marie W Wooten
p62 serves as a shuttling factor for TrkA interaction with the proteasome.
Biochemical and biophysical research communications 2008;374(1):33-7.
2008: Li Chen; Kiran Madura
Centrin/Cdc31 is a novel regulator of protein degradation.
Molecular and cellular biology 2008;28(5):1829-40.
2008: Nadia Hedhli; Li Wang; Qian Wang; Eman Rashed; Yimin Tian; Xiangzhen Sui; Kiran Madura; Christophe Depre
Proteasome activation during cardiac hypertrophy by the chaperone H11 Kinase/Hsp22.
Cardiovascular research 2008;77(3):497-505.
2007: Lizbeth Romero-Perez; Li Chen; David Lambertson; Kiran Madura
Sts1 can overcome the loss of Rad23 and Rpn10 and represents a novel regulator of the ubiquitin/proteasome pathway.
The Journal of biological chemistry 2007;282(49):35574-82.
2006: Christophe Depre; Qian Wang; Lin Yan; Nadia Hedhli; Pallavi Peter; Li Chen; Chull Hong; Luc Hittinger; Bijan Ghaleh; Junichi Sadoshima; Dorothy E Vatner; Stephen F Vatner; Kiran Madura
Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy.
Circulation 2006;114(17):1821-8.
2006: Li Chen; Mona Thiruchelvam; Kiran Madura; Eric K Richfield
Proteasome dysfunction in aged human alpha-synuclein transgenic mice.
Neurobiology of disease 2006;23(1):120-6.
2006: Li Chen; Kiran Madura
Evidence for distinct functions for human DNA repair factors hHR23A and hHR23B.
FEBS letters 2006;580(14):3401-8.
2005: Show-Mei Chuang; Kiran Madura
Saccharomyces cerevisiae Ub-conjugating enzyme Ubc4 binds the proteasome in the presence of translationally damaged proteins.
Genetics 2005;171(4):1477-84.
2005: Li Chen; Kiran Madura
Increased proteasome activity, ubiquitin-conjugating enzymes, and eEF1A translation factor detected in breast cancer tissue.
Cancer research 2005;65(13):5599-606.
2005: Ellen W Doss-Pepe; Li Chen; Kiran Madura
Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains.
The Journal of biological chemistry 2005;280(17):16619-24.
2005: Show-Mei Chuang; Li Chen; David Lambertson; Monika Anand; Terri Goss Kinzy; Kiran Madura
Proteasome-mediated degradation of cotranslationally damaged proteins involves translation elongation factor 1A.
Molecular and cellular biology 2005;25(1):403-13.
2004: Kiran Madura
Rad23 and Rpn10: perennial wallflowers join the melee.
Trends in biochemical sciences 2004;29(12):637-40.
2004: Jennifer A Johnston; Kiran Madura
Rings, chains and ladders: ubiquitin goes to work in the neuron.
Progress in neurobiology 2004;73(4):227-57.
2004: Tatiana G Ortolan; Li Chen; Prasad Tongaonkar; Kiran Madura
Rad23 stabilizes Rad4 from degradation by the Ub/proteasome pathway.
Nucleic acids research 2004;32(22):6490-500.
2003: Ellen W Doss-Pepe; Edward S Stenroos; William G Johnson; Kiran Madura
Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis.
Molecular and cellular biology 2003;23(18):6469-83.
2003: David Lambertson; Li Chen; Kiran Madura
Investigating the importance of proteasome-interaction for Rad23 function.
Current genetics 2003;42(4):199-208.
2002: Lori Lommel; Tatiana G Ortolan; Li Chen; Kiran Madura; Kevin S Sweder
Proteolysis of a nucleotide excision repair protein by the 26 S proteasome.
Current genetics 2002;42(1):9-20.
2002: Kiran Madura
The ubiquitin-associated (UBA) domain: on the path from prudence to prurience.
Cell cycle (Georgetown, Tex.) 2002;1(4):235-44.
2002: Li Chen; Kiran Madura
Rad23 promotes the targeting of proteolytic substrates to the proteasome.
Molecular and cellular biology 2002;22(13):4902-13.
2001: Li Chen; Ujwal Shinde; Tatiana G Ortolan; Kiran Madura
Ubiquitin-associated (UBA) domains in Rad23 bind ubiquitin and promote inhibition of multi-ubiquitin chain assembly.
EMBO reports 2001;2(10):933-8.
2000: Lori Lommel; Li Chen; Kiran Madura; Kevin S Sweder
The 26S proteasome negatively regulates the level of overall genomic nucleotide excision repair.
Nucleic acids research 2000;28(24):4839-45.
2000: Tatiana G Ortolan; Prasad Tongaonkar; David Lambertson; Li Chen; C Schauber; Kiran Madura
The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly.
Nature cell biology 2000;2(9):601-8.
2000: Prasad Tongaonkar; Li Chen; David Lambertson; B Ko; Kiran Madura
Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome.
Molecular and cellular biology 2000;20(13):4691-8.
1999: David Lambertson; Li Chen; Kiran Madura
Pleiotropic defects caused by loss of the proteasome-interacting factors Rad23 and Rpn10 of Saccharomyces cerevisiae.
Genetics 1999;153(1):69-79.
1999: Prasad Tongaonkar; K Beck; Ujwal Shinde; Kiran Madura
Characterization of a temperature-sensitive mutant of a ubiquitin-conjugating enzyme and its use as a heat-inducible degradation signal.
Analytical biochemistry 1999;272(2):263-9.
1998: D Finley; K Tanaka; C Mann; H Feldmann; Mark Hochstrasser; R Vierstra; S Johnston; R Hampton; J Haber; J Mccusker; P Silver; L Frontali; P Thorsness; Alexander Varshavsky; Breck E Byers; Kiran Madura; S I Reed; D Wolf; Stefan Jentsch; T Sommer; Wolfgang Baumeister; A Goldberg; VA Fried; DM Rubin; A Toh-e
Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle.
Trends in biochemical sciences 1998;23(7):244-5.
1998: Prasad Tongaonkar; Kiran Madura
Reconstituting ubiquitination reactions with affinity-purified components and 32P-ubiquitin.
Analytical biochemistry 1998;260(2):135-41.
1998: C Schauber; Li Chen; Prasad Tongaonkar; IE Vega; Kiran Madura
Sequence elements that contribute to the degradation of yeast G alpha.
Genes to cells : devoted to molecular & cellular mechanisms 1998;3(5):307-19.
1998: C Schauber; Li Chen; Prasad Tongaonkar; IE Vega; David Lambertson; W Potts; Kiran Madura
Rad23 links DNA repair to the ubiquitin/proteasome pathway.
Nature 1998;391(6668):715-8.
1994: Kiran Madura; Alexander Varshavsky
Degradation of G alpha by the N-end rule pathway.
Science (New York, N.Y.) 1994;265(5177):1454-8.
1993: Kiran Madura; R J Dohmen; Alexander Varshavsky
N-recognin/Ubc2 interactions in the N-end rule pathway.
The Journal of biological chemistry 1993;268(16):12046-54.
1991: R J Dohmen; Kiran Madura; B Bartel; Alexander Varshavsky
The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(16):7351-5.
1990: Kiran Madura; Satya Prakash
Transcript levels of the Saccharomyes cerevisiae DNA repair gene RAD23 increase in response to UV light and in meiosis but remain constant in the mitotic cell cycle.
Nucleic acids research 1990;18(16):4737-42.
1990: Kiran Madura; Satya Prakash
The Saccharomyces cerevisiae DNA repair gene RAD2 is regulated in meiosis but not during the mitotic cell cycle.
Molecular and cellular biology 1990;10(6):3256-7.
1990: Kiran Madura; Satya Prakash; Louise Prakash
Expression of the Saccharomyces cerevisiae DNA repair gene RAD6 that encodes a ubiquitin conjugating enzyme, increases in response to DNA damage and in meiosis but remains constant during the mitotic cell cycle.
Nucleic acids research 1990;18(4):771-8.
1986: Kiran Madura; S Prakash
Nucleotide sequence, transcript mapping, and regulation of the RAD2 gene of Saccharomyces cerevisiae.
Journal of bacteriology 1986;166(3):914-23.
1985: J Bruenn; Kiran Madura; A Siegel; Z Miner; M Lee
Long internal inverted repeat in a yeast viral double-stranded RNA.
Nucleic acids research 1985;13(5):1575-91.