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Jun Maeda

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Masayuki Fujinaga; Akiko Hatori; Kazunori Kawamura; Katsushi Kumata; Jun Maeda; Yuji Nagai; Nobuki Nengaki; Lin Xie; Tomoteru Yamasaki; Joji Yui; Ming-Rong Zhang
Development of N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methyl-4-[11C]methylbenzamide for positron emission tomography imaging of metabotropic glutamate 1 receptor in monkey brain.
Takaaki Mori; Hitoshi Shimada; Hitoshi Shinotoh; Makoto Higuchi; Jun Maeda; Shu-ichi Ueno; Tetsuya Suhara
Molecular imaging of dementia.
Tomoteru Yamasaki; Yuichiro Yoshida; Joji Yui; Masayuki Fujinaga; Toshimitsu Fukumura; Akiko Hatori; Makoto Higuchi; Kazunori Kawamura; Jun Maeda; Yuji Nagai; Tetsuya Suhara; Masaki Tokunaga; Ming-Rong Zhang
Imaging for metabotropic glutamate receptor subtype 1 in rat and monkey brains using PET with [18F]FITM.

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2012: Masayuki Fujinaga; Akiko Hatori; Kazunori Kawamura; Katsushi Kumata; Jun Maeda; Yuji Nagai; Nobuki Nengaki; Lin Xie; Tomoteru Yamasaki; Joji Yui; Ming-Rong Zhang
Development of N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methyl-4-[11C]methylbenzamide for positron emission tomography imaging of metabotropic glutamate 1 receptor in monkey brain.
Journal of medicinal chemistry 2012;55(24):11042-51.
2012: Takaaki Mori; Hitoshi Shimada; Hitoshi Shinotoh; Makoto Higuchi; Jun Maeda; Shu-ichi Ueno; Tetsuya Suhara
Molecular imaging of dementia.
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society 2012;12(2):106-14.
2012: Tomoteru Yamasaki; Yuichiro Yoshida; Joji Yui; Masayuki Fujinaga; Toshimitsu Fukumura; Akiko Hatori; Makoto Higuchi; Kazunori Kawamura; Jun Maeda; Yuji Nagai; Tetsuya Suhara; Masaki Tokunaga; Ming-Rong Zhang
Imaging for metabotropic glutamate receptor subtype 1 in rat and monkey brains using PET with [18F]FITM.
European journal of nuclear medicine and molecular imaging 2012;39(4):632-41.
2012: Masayuki Fujinaga; Toshimitsu Fukumura; Akiko Hatori; Makoto Higuchi; Kazunori Kawamura; Katsushi Kumata; Jun Maeda; Yuji Nagai; Tetsuya Suhara; Tomoteru Yamasaki; Yuichiro Yoshida; Joji Yui; Ming-Rong Zhang
Characterization of 1-(2-[18F] fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo- isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole, a PET ligand for imaging the metabotropic glutamate receptor type 1 in rat and monkey brains.
Journal of neurochemistry 2012;121(1):115-24.
2012: Takeaki Saijo; Tetsuya Suhara; Masayuki Suzuki; Toshimitsu Fukumura; Nobuharu Goto; Yasuhiro Kuwahara; Jun Maeda; Jun-ichi Maeda; Yasunori Morio; Takashi Okauchi; Makoto Higuchi
Presynaptic selectivity of a ligand for serotonin 1A receptors revealed by in vivo PET assays of rat brain.
PloS one 2012;7(8):e42589.
2012: Makoto Higuchi; Bin Ji; Jun Maeda; Masahiro Maruyama; Maiko Ono; Masaki Tokunaga; Ming-Rong Zhang; Toshimitsu Fukumura; Tetsuya Suhara
PET Applications in Animal Models of Neurodegenerative and Neuroinflammatory Disorders.
Current topics in behavioral neurosciences 2012;11():45-64.
2011: Makoto Higuchi; Bin Ji; Jun Maeda; Masahiro Maruyama; Maiko Ono; Makoto Sawada; Tetsuya Suhara
[Alzheimer's disease and microglia].
Rinshō shinkeigaku = Clinical neurology 2011;51(11):1031.
2011: Kazunori Kawamura; Jun Maeda; Akiko Hatori; Takashi Okauchi; Yuji Nagai; Makoto Higuchi; Tetsuya Suhara; Toshimitsu Fukumura; Ming-Rong Zhang
In vivo and in vitro imaging of I₂ imidazoline receptors in the monkey brain.
Synapse (New York, N.Y.) 2011;65(5):452-5.
2011: Mizuho Sekine; Hitoshi Shimada; Harumasa Takano; Ryosuke Arakawa; Makoto Higuchi; Hiroshi Ito; Jun Maeda; Tsuyoshi Nogami; Yoshiro Okubo; Tetsuya Suhara
Central nervous system drug evaluation using positron emission tomography.
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology 2011;9(1):9-16.
2011: Jun Maeda; Ming-Rong Zhang; Takashi Okauchi; Bin Ji; Maiko Ono; Satoko Hattori; Katsushi Kumata; Nobuhisa Iwata; Takaomi C Saido; John Q Trojanowski; Virginia M-Y Lee; Matthias Staufenbiel; Takami Tomiyama; Hiroshi Mori; Toshimitsu Fukumura; Tetsuya Suhara; Makoto Higuchi
In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(12):4720-30.
2011: Masayuki Fujinaga; Tomoteru Yamasaki; Kazunori Kawamura; Katsushi Kumata; Akiko Hatori; Joji Yui; Kazuhiko Yanamoto; Yuichiro Yoshida; Masanao Ogawa; Nobuki Nengaki; Jun Maeda; Toshimitsu Fukumura; Ming-Rong Zhang
Synthesis and evaluation of 6-[1-(2-[(18)F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain.
Bioorganic & medicinal chemistry 2011;19(1):102-10.
2010: Ryosuke Arakawa; Masaki Okumura; Hiroshi Ito; Akihiro Takano; Hidehiko Takahashi; Harumasa Takano; Jun Maeda; Yoshiro Okubo; Tetsuya Suhara
Positron emission tomography measurement of dopamine D₂ receptor occupancy in the pituitary and cerebral cortex: relation to antipsychotic-induced hyperprolactinemia.
The Journal of clinical psychiatry 2010;71(9):1131-7.
2010: Joji Yui; Jun Maeda; Katsushi Kumata; Kazunori Kawamura; Kazuhiko Yanamoto; Akiko Hatori; Tomoteru Yamasaki; Nobuki Nengaki; Makoto Higuchi; Ming-Rong Zhang
18F-FEAC and 18F-FEDAC: PET of the monkey brain and imaging of translocator protein (18 kDa) in the infarcted rat brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(8):1301-9.
2010: Iwae Yu; Motoki Inaji; Jun Maeda; Takashi Okauchi; Tadashi Nariai; Kikuo Ohno; Makoto Higuchi; Tetsuya Suhara
Glial cell-mediated deterioration and repair of the nervous system after traumatic brain injury in a rat model as assessed by positron emission tomography.
Journal of neurotrauma 2010;27(8):1463-75.
2010: Chie Seki; Hiroshi Ito; Tetsuya Ichimiya; Ryosuke Arakawa; Yoko Ikoma; Miho Shidahara; Jun Maeda; Akihiro Takano; Hidehiko Takahashi; Yuichi Kimura; Kazutoshi Suzuki; Iwao Kanno; Tetsuya Suhara
Quantitative analysis of dopamine transporters in human brain using [11C]PE2I and positron emission tomography: evaluation of reference tissue models.
Annals of nuclear medicine 2010;24(4):249-60.
2010: Makoto Higuchi; Jun Maeda; Bin Ji; Masahiro Maruyama; Takashi Okauchi; Masaki Tokunaga; Maiko Ono; Tetsuya Suhara
In-vivo visualization of key molecular processes involved in Alzheimer's disease pathogenesis: Insights from neuroimaging research in humans and rodent models.
Biochimica et biophysica acta 2010;1802(4):373-88.
2010: Masayuki Fujinaga; Katsushi Kumata; Kazuhiko Yanamoto; Kazunori Kawamura; Tomoteru Yamasaki; Joji Yui; Akiko Hatori; Masanao Ogawa; Yuichiro Yoshida; Nobuki Nengaki; Jun Maeda; Ming-Rong Zhang
Radiosynthesis of novel carbon-11-labeled triaryl ligands for cannabinoid-type 2 receptor.
Bioorganic & medicinal chemistry letters 2010;20(5):1565-8.
2009: Yoshiyuki Asai; Yoko Ikoma; Akihiro Takano; Jun Maeda; Hinako Toyama; Fumihiko Yasuno; Tetsuya Ichimiya; Hiroshi Ito; Tetsuya Suhara
Quantitative analyses of [¹¹C]Ro15-4513 binding to subunits of GABAA/benzodiazepine receptor in the living human brain.
Nuclear medicine communications 2009;30(11):872-80.
2009: Takeaki Saijo; Jun Maeda; Takashi Okauchi; Jun Maeda; Yasunori Morio; Yasuhiro Kuwahara; Masayuki Suzuki; Nobuharu Goto; Kazutoshi Suzuki; Makoto Higuchi; Tetsuya Suhara
Utility of small-animal positron emission tomographic imaging of rats for preclinical development of drugs acting on the serotonin transporter.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2009;12(8):1021-32.
2009: Takeshi Fuchigami; Terushi Haradahira; Noriko Fujimoto; Yumiko Nojiri; Takahiro Mukai; Fumihiko Yamamoto; Takashi Okauchi; Jun Maeda; Kazutoshi Suzuki; Tetsuya Suhara; Hiroshi Yamaguchi; Mikako Ogawa; Yasuhiro Magata; Minoru Maeda
Development of N-[11C]methylamino 4-hydroxy-2(1H)-quinolone derivatives as PET radioligands for the glycine-binding site of NMDA receptors.
Bioorganic & medicinal chemistry 2009;17(15):5665-75.
2009: Shigeru Obayashi; Yuji Nagai; Tetsuya Suhara; Takashi Okauchi; Motoki Inaji; Atsushi Iriki; Jun Maeda
Monkey brain activity modulated by reward preferences: a positron emission tomography study.
Neuroscience research 2009;64(4):421-8.
2009: Michie Miyoshi; Hiroshi Ito; Ryosuke Arakawa; Hidehiko Takahashi; Harumasa Takano; Makoto Higuchi; Masaki Okumura; Tatsui Otsuka; Fumitoshi Kodaka; Mizuho Sekine; Takeshi Sasaki; Saori Fujie; Chie Seki; Jun Maeda; Ryuji Nakao; Ming-Rong Zhang; Toshimitsu Fukumura; Masayasu Matsumoto; Tetsuya Suhara
Quantitative analysis of peripheral benzodiazepine receptor in the human brain using PET with (11)C-AC-5216.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(7):1095-101.
2009: Jun Maeda; Makoto Higuchi; Tetsuya Suhara
[Evaluation of imaging biomarker by transgenic mouse models].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 2009;29(2):73-8.
2009: Masaki Tokunaga; Nicholas Seneca; Ryong-Moon Shin; Jun Maeda; Shigeru Obayashi; Takashi Okauchi; Yuji Nagai; Ming-Rong Zhang; Ryuji Nakao; Hiroshi Ito; Robert B Innis; Christer Halldin; Kazutoshi Suzuki; Makoto Higuchi; Tetsuya Suhara
Neuroimaging and physiological evidence for involvement of glutamatergic transmission in regulation of the striatal dopaminergic system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(6):1887-96.
2008: Bin Ji; Jun Maeda; Makoto Sawada; Maiko Ono; Takashi Okauchi; Motoki Inaji; Ming-Rong Zhang; Kazutoshi Suzuki; Kiyoshi Ando; Matthias Staufenbiel; John Q Trojanowski; Virginia M-Y Lee; Makoto Higuchi; Tetsuya Suhara
Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(47):12255-67.
2008: Takeshi Fuchigami; Terushi Haradahira; Noriko Fujimoto; Takashi Okauchi; Jun Maeda; Kazutoshi Suzuki; Tetsuya Suhara; Fumihiko Yamamoto; Shigeki Sasaki; Takahiro Mukai; Hiroshi Yamaguchi; Mikako Ogawa; Yasuhiro Magata; Minoru Maeda
Difference in brain distributions of carbon 11-labeled 4-hydroxy-2(1H)-quinolones as PET radioligands for the glycine-binding site of the NMDA ion channel.
Nuclear medicine and biology 2008;35(2):203-12.
2008: Kiyoshi Ando; Jun Maeda; Motoki Inaji; Takashi Okauchi; Shigeru Obayashi; Makoto Higuchi; Tetsuya Suhara; Yoshikuni Tanioka
Neurobehavioral protection by single dose l-deprenyl against MPTP-induced parkinsonism in common marmosets.
Psychopharmacology 2008;195(4):509-16.
2007: Ming-Rong Zhang; Katsushi Kumata; Jun Maeda; Kazuhiko Yanamoto; Akiko Hatori; Maki Okada; Makoto Higuchi; Shigeru Obayashi; Tetsuya Suhara; Kazutoshi Suzuki
11C-AC-5216: a novel PET ligand for peripheral benzodiazepine receptors in the primate brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(11):1853-61.
2007: Jun Maeda; Bin Ji; Toshiaki Irie; Takami Tomiyama; Masahiro Maruyama; Takashi Okauchi; Matthias Staufenbiel; Nobuhisa Iwata; Maiko Ono; Takaomi C Saido; Kazutoshi Suzuki; Hiroshi Mori; Makoto Higuchi; Tetsuya Suhara
Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(41):10957-68.
2007: Ryohei Matsumoto; Terushi Haradahira; Hiroshi Ito; Yota Fujimura; Chie Seki; Yoko Ikoma; Jun Maeda; Ryosuke Arakawa; Akihiro Takano; Hidehiko Takahashi; Makoto Higuchi; Kazutoshi Suzuki; Kenji Fukui; Tetsuya Suhara
Measurement of glycine binding site of N-methyl-D-asparate receptors in living human brain using 4-acetoxy derivative of L-703,717, 4-acetoxy-7-chloro-3-[3-(4-[11c] methoxybenzyl) phenyl]-2(1H)-quinolone (AcL703) with positron emission tomography.
Synapse (New York, N.Y.) 2007;61(10):795-800.
2007: Yuji Nagai; Shigeru Obayashi; Kiyoshi Ando; Motoki Inaji; Jun Maeda; Takashi Okauchi; Hiroshi Ito; Tetsuya Suhara
Progressive changes of pre- and post-synaptic dopaminergic biomarkers in conscious MPTP-treated cynomolgus monkeys measured by positron emission tomography.
Synapse (New York, N.Y.) 2007;61(10):809-19.
2007: Jun Maeda; Makoto Higuchi; Motoki Inaji; Bin Ji; Eisuke Haneda; Takashi Okauchi; Ming-Rong Zhang; Kazutoshi Suzuki; Tetsuya Suhara
Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor.
Brain research 2007;1157():100-11.
2007: Fumihiko Yasuno; Miho Ota; Kiyoshi Ando; Tomomichi Ando; Jun Maeda; Tetsuya Ichimiya; Akihiro Takano; Talant K Doronbekov; Yota Fujimura; Shoko Nozaki; Tetsuya Suhara
Role of ventral striatal dopamine D1 receptor in cigarette craving.
Biological psychiatry 2007;61(11):1252-9.
2007: Shigeru Obayashi; Ryohei Matsumoto; Tetsuya Suhara; Yuji Nagai; Atsushi Iriki; Jun Maeda
Functional organization of monkey brain for abstract operation.
Cortex; a journal devoted to the study of the nervous system and behavior 2007;43(3):389-96.
2007: Eisuke Haneda; Makoto Higuchi; Jun Maeda; Motoki Inaji; Takashi Okauchi; Kiyoshi Ando; Shigeru Obayashi; Yuji Nagai; Michiko Narazaki; Hiroo Ikehira; Ryuji Nakao; Ming-Rong Zhang; Kazutoshi Suzuki; Hidenori Suzuki; Tetsuya Suhara
In vivo mapping of substance P receptors in brains of laboratory animals by high-resolution imaging systems.
Synapse (New York, N.Y.) 2007;61(4):205-15.
2007: Ming-Rong Zhang; Katsushi Kumata; Jun Maeda; Terushi Haradahira; Junko Noguchi; Tetsuya Suhara; Christer Halldin; Kazutoshi Suzuki
N-(5-Fluoro-2-phenoxyphenyl)-N-(2-[(131)I]iodo-5-me thoxybenzyl)acetamide: a potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain.
Journal of medicinal chemistry 2007;50(4):848-55.
2007: Yoko Ikoma; Fumihiko Yasuno; Hiroshi Ito; Tetsuya Suhara; Miho Ota; Hinako Toyama; Yota Fujimura; Akihiro Takano; Jun Maeda; Ming-Rong Zhang; Ryuji Nakao; Kazutoshi Suzuki
Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [(11)C]DAA1106.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(1):173-84.
2006: Akihiro Takano; Hiroyuki Kusuhara; Tetsuya Suhara; Ichiro Ieiri; Takuya Morimoto; Young-Joo Lee; Jun Maeda; Yoko Ikoma; Hiroshi Ito; Kazutoshi Suzuki; Yuichi Sugiyama
Evaluation of in vivo P-glycoprotein function at the blood-brain barrier among MDR1 gene polymorphisms by using 11C-verapamil.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(9):1427-33.
2006: Hiroshi Ito; Miho Ota; Yoko Ikoma; Chie Seki; Fumihiko Yasuno; Akihiro Takano; Jun Maeda; Ryuji Nakao; Kazutoshi Suzuki; Tetsuya Suhara
Quantitative analysis of dopamine synthesis in human brain using positron emission tomography with L-[beta-11C]DOPA.
Nuclear medicine communications 2006;27(9):723-31.
2006: Ming-Rong Zhang; Masanao Ogawa; Jun Maeda; Takehito Ito; Junko Noguchi; Katsushi Kumata; Takashi Okauchi; Tetsuya Suhara; Kazutoshi Suzuki
[2-11C]isopropyl-, [1-11C]ethyl-, and [11C]methyl-labeled phenoxyphenyl acetamide derivatives as positron emission tomography ligands for the peripheral benzodiazepine receptor: radiosynthesis, uptake, and in vivo binding in brain.
Journal of medicinal chemistry 2006;49(9):2735-42.
2006: Jun Maeda; Makoto Higuchi; Tetsuya Suhara
[Imaging of glial cells by positron-emitted peripheral benzodiazepine receptor ligands].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 2006;26(1):17-21.
2006: Young-Joo Lee; Jun Maeda; Hiroyuki Kusuhara; Takashi Okauchi; Motoki Inaji; Yuji Nagai; Shigeru Obayashi; Ryuji Nakao; Kazutoshi Suzuki; Yuichi Sugiyama; Tetsuya Suhara
In vivo evaluation of P-glycoprotein function at the blood-brain barrier in nonhuman primates using [11C]verapamil.
The Journal of pharmacology and experimental therapeutics 2006;316(2):647-53.
2006: Bin Ji; Jun Maeda; Makoto Higuchi; Kaori Inoue; Hidetaka Akita; Hideyoshi Harashima; Tetsuya Suhara
Pharmacokinetics and brain uptake of lactoferrin in rats.
Life sciences 2006;78(8):851-5.
2005: Motoki Inaji; Takashi Okauchi; Kiyoshi Ando; Jun Maeda; Yuji Nagai; Takahito Yoshizaki; Hideyuki Okano; Tadashi Nariai; Kikuo Ohno; Shigeru Obayashi; Makoto Higuchi; Tetsuya Suhara
Correlation between quantitative imaging and behavior in unilaterally 6-OHDA-lesioned rats.
Brain research 2005;1064(1-2):136-45.
2005: Ming-Rong Zhang; Jun Maeda; Takehito Ito; Takashi Okauchi; Masanao Ogawa; Junko Noguchi; Tetsuya Suhara; Christer Halldin; Kazutoshi Suzuki
Synthesis and evaluation of N-(5-fluoro-2-phenoxyphenyl)-N-(2-[(18)F]fluoromethoxy-d(2)-5-methoxybenzyl)acetamide: a deuterium-substituted radioligand for peripheral benzodiazepine receptor.
Bioorganic & medicinal chemistry 2005;13(5):1811-8.
2005: Motoki Inaji; Takahito Yoshizaki; Takashi Okauchi; Jun Maeda; Yuji Nagai; Tadashi Nariai; Kikuo Ohno; Kiyoshi Ando; Hideyuki Okano; Shigeru Obayashi; Tetsuya Suhara
In vivo PET measurements with [11C]PE2I to evaluate fetal mesencephalic transplantations to unilateral 6-OHDA-lesioned rats.
Cell transplantation 2005;14(9):655-63.
2004: Jun Maeda; Tetsuya Suhara; Ming-Rong Zhang; Takashi Okauchi; Fumihiko Yasuno; Yoko Ikoma; Motoki Inaji; Yuji Nagai; Akihiro Takano; Shigeru Obayashi; Kazutoshi Suzuki
Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain.
Synapse (New York, N.Y.) 2004;52(4):283-91.
2004: Akihiro Takano; Tetsuya Suhara; Jun Maeda; Kiyoshi Ando; Takashi Okauchi; Shigeru Obayashi; Takashi Nakayama; Shitij Kapur
Relation between cortical dopamine D(2) receptor occupancy and suppression of conditioned avoidance response in non-human primate.
Psychiatry and clinical neurosciences 2004;58(3):330-2.
2004: Ming-Rong Zhang; Jun Maeda; Masanao Ogawa; Junko Noguchi; Takehito Ito; Yuichiro Yoshida; Takashi Okauchi; Shigeru Obayashi; Tetsuya Suhara; Kazutoshi Suzuki
Development of a new radioligand, N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoroethyl-5-methoxybenzyl)acetamide, for pet imaging of peripheral benzodiazepine receptor in primate brain.
Journal of medicinal chemistry 2004;47(9):2228-35.
2004: Shigeki Sasaki; Fumie Kurosaki; Terushi Haradahira; Fumihiko Yamamoto; Jun Maeda; Takashi Okauchi; Kazutoshi Suzuki; Tetsuya Suhara; Minoru Maeda
Synthesis of 11C-labelled bis(phenylalkyl)amines and their in vitro and in vivo binding properties in rodent and monkey brains.
Biological & pharmaceutical bulletin 2004;27(4):531-7.
2004: Shigeru Obayashi; Tetsuya Suhara; Yuji Nagai; Takashi Okauchi; Jun Maeda; Atsushi Iriki
Monkey brain areas underlying remote-controlled operation.
The European journal of neuroscience 2004;19(5):1397-407.
2004: Akihiro Takano; Tetsuya Suhara; Yoko Ikoma; Fumihiko Yasuno; Jun Maeda; Tetsuya Ichimiya; Yasuhiko Sudo; Makoto Inoue; Yoshiro Okubo
Estimation of the time-course of dopamine D2 receptor occupancy in living human brain from plasma pharmacokinetics of antipsychotics.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2004;7(1):19-26.
2004: Jun'ichi Semba; Maki Wakuta; Jun Maeda; Tetsuya Suhara
Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats: implications for precipitation of depression during smoking cessation.
Psychoneuroendocrinology 2004;29(2):215-26.
2003: Takeshi Fuchigami; Terushi Haradahira; Takuya Arai; Takashi Okauchi; Jun Maeda; Kazutoshi Suzuki; Fumihiko Yamamoto; Tetsuya Suhara; Shigeki Sasaki; Minoru Maeda
Synthesis and brain regional distribution of [11C]NPS 1506 in mice and rat: an N-methyl-D-aspartate (NMDA) receptor antagonist.
Biological & pharmaceutical bulletin 2003;26(11):1570-3.
2003: Terushi Haradahira; Takashi Okauchi; Jun Maeda; Ming-Rong Zhang; Toru Nishikawa; Ryouichi Konno; Kazutoshi Suzuki; Tetsuya Suhara
Effects of endogenous agonists, glycine and D-serine, on in vivo specific binding of [11C]L-703,717, a PET radioligand for the glycine-binding site of NMDA receptors.
Synapse (New York, N.Y.) 2003;50(2):130-6.
2003: Ming-Rong Zhang; Takayo Kida; Junko Noguchi; Kenji Furutsuka; Jun Maeda; Tetsuya Suhara; Kazutoshi Suzuki
[(11)C]DAA1106: radiosynthesis and in vivo binding to peripheral benzodiazepine receptors in mouse brain.
Nuclear medicine and biology 2003;30(5):513-9.
2003: Ming-Rong Zhang; Kenji Furutsuka; Jun Maeda; Tatsuya Kikuchi; Takayo Kida; Takashi Okauchi; Toshiaki Irie; Kazutoshi Suzuki
N-[18F]fluoroethyl-4-piperidyl acetate ([18F]FEtP4A): A PET tracer for imaging brain acetylcholinesterase in vivo.
Bioorganic & medicinal chemistry 2003;11(12):2519-27.
2003: Shigeru Obayashi; Tetsuya Suhara; Kouichi Kawabe; Takashi Okauchi; Jun Maeda; Yuji Nagai; Atsushi Iriki
Fronto-parieto-cerebellar interaction associated with intermanual transfer of monkey tool-use learning.
Neuroscience letters 2003;339(2):123-6.
2003: Jun Maeda; Tetsuya Suhara; Kouichi Kawabe; Takashi Okauchi; Shigeru Obayashi; Junko Hojo; Kazutoshi Suzuki
Visualization of alpha5 subunit of GABAA/benzodiazepine receptor by 11C Ro15-4513 using positron emission tomography.
Synapse (New York, N.Y.) 2003;47(3):200-8.
2003: Fumihiko Yasuno; Tetsuya Suhara; Takashi Nakayama; Tetsuya Ichimiya; Yoshiro Okubo; Akihiro Takano; Tomomichi Ando; Makoto Inoue; Jun Maeda; Kazutoshi Suzuki
Inhibitory effect of hippocampal 5-HT1A receptors on human explicit memory.
The American journal of psychiatry 2003;160(2):334-40.
2003: Jun Maeda; Tetsuya Suhara; Takashi Okauchi; Jun'ichi Semba
Different roles of group I and group II metabotropic glutamate receptors on phencyclidine-induced dopamine release in the rat prefrontal cortex.
Neuroscience letters 2003;336(3):171-4.
2003: Ming-Rong Zhang; Jun Maeda; Kenji Furutsuka; Yuichiro Yoshida; Masanao Ogawa; Tetsuya Suhara; Kazutoshi Suzuki
[18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR).
Bioorganic & medicinal chemistry letters 2003;13(2):201-4.
2002: Shigeru Obayashi; Tetsuya Suhara; Yuji Nagai; Jun Maeda; Sayaka Hihara; Atsushi Iriki
Macaque prefrontal activity associated with extensive tool use.
Neuroreport 2002;13(17):2349-54.
2002: Takashi Nakayama; Tetsuya Suhara; Yoshiro Okubo; Tetsuya Ichimiya; Fumihiko Yasuno; Jun Maeda; Akihiro Takano; Tomoyuki Saijo; Kazutoshi Suzuki
In vivo drug action of tandospirone at 5-HT1A receptor examined using positron emission tomography and neuroendocrine response.
Psychopharmacology 2002;165(1):37-42.
2002: Terushi Haradahira; Jun Maeda; Takashi Okauchi; Ming-Rong Zhang; Junko Hojo; Takayo Kida; Takuya Arai; Fumihiko Yamamoto; Shigeki Sasaki; Minoru Maeda; Kazutoshi Suzuki; Tetsuya Suhara
Synthesis, in vitro and in vivo pharmacology of a C-11 labeled analog of CP-101,606, (+/-)threo-1-(4-hydroxyphenyl)-2-[4-hydroxy-4-(p-[11C]methoxyphenyl)piperidino]-1-propanol, as a PET tracer for NR2B subunit-containing NMDA receptors.
Nuclear medicine and biology 2002;29(5):517-25.
2002: Ming-Rong Zhang; Terushi Haradahira; Jun Maeda; Takashi Okauchi; Kouichi Kawabe; Takayo Kida; Shigeru Obayashi; Kazutoshi Suzuki; Tetsuya Suhara
Synthesis and evaluation of 3-(4-chlorobenzyl)-8-[11C]methoxy-1,2,3,4-tetrahydrochromeno[3,4-c]pyridin-5-one: a PET tracer for imaging sigma(1) receptors.
Nuclear medicine and biology 2002;29(4):469-76.
2002: Tetsuya Ichimiya; Tetsuya Suhara; Yasuhiko Sudo; Yoshiro Okubo; Kazuhiko Nakayama; Masahiro Nankai; Makoto Inoue; Fumihiko Yasuno; Akihiro Takano; Jun Maeda; Haruo Shibuya
Serotonin transporter binding in patients with mood disorders: a PET study with [11C](+)McN5652.
Biological psychiatry 2002;51(9):715-22.
2002: Tetsuya Suhara; Takashi Okauchi; Yasuhiko Sudo; Akihiro Takano; Kouichi Kawabe; Jun Maeda; Shitij Kapur
Clozapine can induce high dopamine D(2) receptor occupancy in vivo.
Psychopharmacology 2002;160(1):107-12.
2002: Ming-Rong Zhang; Terushi Haradahira; Jun Maeda; Takashi Okauchi; Kouichi Kawabe; Junko Noguchi; Takayo Kida; Kazutoshi Suzuki; Tetsuya Suhara
Syntheses and pharmacological evaluation of two potent antagonists for dopamine D4 receptors: [11C]YM-50001 and N-[2-[4-(4-Chlorophenyl)-piperizin-1-yl]ethyl]-3-[11C]methoxybenzamide.
Nuclear medicine and biology 2002;29(2):233-41.
2002: Terushi Haradahira; Takashi Okauchi; Jun Maeda; Ming-Rong Zhang; Takayo Kida; Kouichi Kawabe; Masayoshi Mishina; Yasuyoshi Watanabe; Kazutoshi Suzuki; Tetsuya Suhara
A positron-emitter labeled glycine(B) site antagonist, [(11)C]L-703,717, preferentially binds to a cerebellar NMDA receptor subtype consisting of GluR epsilon3 subunit in vivo, but not in vitro.
Synapse (New York, N.Y.) 2002;43(2):131-3.
2001: Shigeru Obayashi; Tetsuya Suhara; Kouichi Kawabe; Takashi Okauchi; Jun Maeda; Yoshihide Akine; H Onoe; Atsushi Iriki
Functional brain mapping of monkey tool use.
NeuroImage 2001;14(4):853-61.
2001: Takashi Okauchi; Tetsuya Suhara; Jun Maeda; Kouichi Kawabe; Shigeru Obayashi; Kazutoshi Suzuki
Effect of endogenous dopamine on endogenous dopamine on extrastriated [11C]FLB 457 binding measured by PET.
Synapse (New York, N.Y.) 2001;41(2):87-95.
2001: Jun Maeda; Tetsuya Suhara; M Ogawa; Takashi Okauchi; K Kawabe; Ming-Rong Zhang; Jun'ichi Semba; K Suzuki
In vivo binding properties of [carbonyl-11C]WAY-100635: effect of endogenous serotonin.
Synapse (New York, N.Y.) 2001;40(2):122-9.
2001: Terushi Haradahira; Ming-Rong Zhang; Jun Maeda; Takashi Okauchi; Takayo Kida; Kouichi Kawabe; S Sasaki; Tetsuya Suhara; Kazutoshi Suzuki
A prodrug of NMDA/glycine site antagonist, L-703,717, with improved BBB permeability: 4-acetoxy derivative and its positron-emitter labeled analog.
Chemical & pharmaceutical bulletin 2001;49(2):147-50.
2000: Terushi Haradahira; M Zhang; Jun Maeda; Takashi Okauchi; Kouichi Kawabe; Takayo Kida; Kazutoshi Suzuki; T Suhara1
A strategy for increasing the brain uptake of a radioligand in animals: use of a drug that inhibits plasma protein binding.
Nuclear medicine and biology 2000;27(4):357-60.