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Minoru Maeda

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Kohei Sano; Kenta Shimokawa; Hayato Hisada; Minoru Maeda; Mayumi Okada; Hideo Saji; Takahiro Mukai
In vivo evaluation of a radiogallium-labeled bifunctional radiopharmaceutical, Ga-DOTA-MN2, for hypoxic tumor imaging.
Jintaek Kim; Tomohiro Kino; Takahiro Mukai; Kohei Sano; Fumihiko Yamamoto; Hiroharu Kato; Minoru Maeda
5-O-(4-[125 I]Iodobenzyl)-L-ascorbic acid: electrophilic radioiodination and biodistribution in mice.
Yuuhei Sano; Tomokazu Motomura; Fumihiko Yamamoto; Miki Fukuda; Takahiro Mukai; Minoru Maeda
1-(3'-[125I]Iodophenyl)-3-methy-2-pyrazolin-5-one: preparation, solution stability, and biodistribution in normal mice.

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All Publications

2013: Kohei Sano; Kenta Shimokawa; Hayato Hisada; Minoru Maeda; Mayumi Okada; Hideo Saji; Takahiro Mukai
In vivo evaluation of a radiogallium-labeled bifunctional radiopharmaceutical, Ga-DOTA-MN2, for hypoxic tumor imaging.
Biological & pharmaceutical bulletin 2013;36(4):602-8.
2012: Jintaek Kim; Tomohiro Kino; Takahiro Mukai; Kohei Sano; Fumihiko Yamamoto; Hiroharu Kato; Minoru Maeda
5-O-(4-[125 I]Iodobenzyl)-L-ascorbic acid: electrophilic radioiodination and biodistribution in mice.
Chemical & pharmaceutical bulletin 2012;60(2):235-40.
2010: Yuuhei Sano; Tomokazu Motomura; Fumihiko Yamamoto; Miki Fukuda; Takahiro Mukai; Minoru Maeda
1-(3'-[125I]Iodophenyl)-3-methy-2-pyrazolin-5-one: preparation, solution stability, and biodistribution in normal mice.
Chemical & pharmaceutical bulletin 2010;58(8):1020-5.
2009: Takeshi Fuchigami; Terushi Haradahira; Noriko Fujimoto; Yumiko Nojiri; Takahiro Mukai; Fumihiko Yamamoto; Takashi Okauchi; Jun Maeda; Kazutoshi Suzuki; Tetsuya Suhara; Hiroshi Yamaguchi; Mikako Ogawa; Yasuhiro Magata; Minoru Maeda
Development of N-[11C]methylamino 4-hydroxy-2(1H)-quinolone derivatives as PET radioligands for the glycine-binding site of NMDA receptors.
Bioorganic & medicinal chemistry 2009;17(15):5665-75.
2009: Takahiro Mukai; Jun Suwada; Kohei Sano; Mayumi Okada; Fumihiko Yamamoto; Minoru Maeda
Design of Ga-DOTA-based bifunctional radiopharmaceuticals: two functional moieties can be conjugated to radiogallium-DOTA without reducing the complex stability.
Bioorganic & medicinal chemistry 2009;17(13):4285-9.
2008: Yumiko Nojiri; Kiichi Ishiwata; Shintaro Tobiishi; Toru Sasada; Fumihiko Yamamoto; Takahiro Mukai; Minoru Maeda
Radiosynthesis and biodistribution in mice of a 18F-labeled analog of O-1302 for use in cerebral CB1 cannabinoid receptor imaging.
Biological & pharmaceutical bulletin 2008;31(6):1274-8.
2008: Takahiro Mukai; Noriko Suganuma; Kenta Soejima; Junichi Sasaki; Fumihiko Yamamoto; Minoru Maeda
Synthesis of a beta-tetrapeptide analog as a mother compound for the development of matrix metalloproteinase-2-imaging agents.
Chemical & pharmaceutical bulletin 2008;56(3):260-5.
2008: Takeshi Fuchigami; Terushi Haradahira; Noriko Fujimoto; Takashi Okauchi; Jun Maeda; Kazutoshi Suzuki; Tetsuya Suhara; Fumihiko Yamamoto; Shigeki Sasaki; Takahiro Mukai; Hiroshi Yamaguchi; Mikako Ogawa; Yasuhiro Magata; Minoru Maeda
Difference in brain distributions of carbon 11-labeled 4-hydroxy-2(1H)-quinolones as PET radioligands for the glycine-binding site of the NMDA ion channel.
Nuclear medicine and biology 2008;35(2):203-12.
2008: Akiko Uemori; Akira Ohgushi; Koichi Yasutake; Minoru Maeda; Eiichi Mizuki; Michio Ohba
Parasporin-1Ab, a novel Bacillus thuringiensis cytotoxin preferentially active on human cancer cells in vitro.
Anticancer research 2008;28(1A):91-5.
2007: Hiroharu Kato; Tomohiro Kino; Fumihiko Yamamoto; Tetsuo Kaneshiro; Takahiro Mukai; Minoru Maeda
Ascorbate analogs for use in medical imaging: synthesis and radical scavenging activity of 5-O-(4'-iodobenzyl)-L-ascorbic acid.
Chemical & pharmaceutical bulletin 2007;55(12):1700-3.
2007: Shintaro Tobiishi; Toru Sasada; Yumiko Nojiri; Fumihiko Yamamoto; Takahiro Mukai; Kiichi Ishiwata; Minoru Maeda
Methoxy- and fluorine-substituted analogs of O-1302: synthesis and in vitro binding affinity for the CB1 cannabinoid receptor.
Chemical & pharmaceutical bulletin 2007;55(8):1213-7.
2007: Akiko Uemori; Minoru Maeda; Koichi Yasutake; Akira Ohgushi; Kumiko Kagoshima; Eiichi Mizuki; Michio Ohba
Ubiquity of parasporin-1 producers in Bacillus thuringiensis natural populations of Japan.
Die Naturwissenschaften 2007;94(1):34-8.
2006: Mariko Tanaka; Yoshihiko Fujisaki; Kazunori Kawamura; Kiichi Ishiwata; Fumihiko Yamamoto; Takahiro Mukai; Minoru Maeda
Radiosynthesis and evaluation of 11C-labeled diaryl-substituted imidazole and indole derivatives for mapping cyclooxygenase-2.
Biological & pharmaceutical bulletin 2006;29(10):2087-94.
2006: Koichi Yasutake; Ngo Dinh Binh; Kumiko Kagoshima; Akiko Uemori; Akira Ohgushi; Minoru Maeda; Eiichi Mizuki; Yong Man Yu; Michio Ohba
Occurrence of parasporin-producing Bacillus thuringiensis in Vietnam.
Canadian journal of microbiology 2006;52(4):365-72.
2006: Md Monsur Ali; Fumi Nagatsugi; Shigeki Sasaki; Ryusuke Nakahara; Minoru Maeda
Application of 2-amino-6-vinylpurine as an efficient agent for conjugation of oligonucleotides.
Nucleosides, nucleotides & nucleic acids 2006;25(2):159-69.
2006: Noriko Shisa; Minoru Maeda; Michio Ohba
Unusual envelopes associated with parasporal inclusions of a mosquitocidal Bacillus thuringiensis serovar fukuokaensis isolate.
Journal of basic microbiology 2006;46(1):64-7.
2005: Yoshihiko Fujisaki; Kazunori Kawamura; Wei-Fang Wang; Kiichi Ishiwata; Fumihiko Yamamoto; Takashi Kuwano; Mayumi Ono; Minoru Maeda
Radiosynthesis and in vivo evaluation of 11C-labeled 1,5-diarylpyrazole derivatives for mapping cyclooxygenases.
Annals of nuclear medicine 2005;19(7):617-25.
2005: Fumihiko Yamamoto; Tetsuo Kaneshiro; Hiroharu Kato; Takahiro Mukai; Yasuo Kuwabara; Hiroshi Honda; Minoru Maeda
Decreased tissue accumulation of 6-deoxy-6-[18F]fluoro-L-ascorbic acid in glutathione-deficient rats induced by administration of diethyl maleate.
Biological & pharmaceutical bulletin 2005;28(10):1943-7.
2005: Takeshi Kawasaki; Fumi Nagatsugi; Md Monsur Ali; Minoru Maeda; Kumiko Sugiyama; Kenji Hori; Shigeki Sasaki
Hybridization-promoted and cytidine-selective activation for cross-linking with the use of 2-amino-6-vinylpurine derivatives.
The Journal of organic chemistry 2005;70(1):14-23.
2004: Shigeki Sasaki; Fumie Kurosaki; Terushi Haradahira; Fumihiko Yamamoto; Jun Maeda; Takashi Okauchi; Kazutoshi Suzuki; Tetsuya Suhara; Minoru Maeda
Synthesis of 11C-labelled bis(phenylalkyl)amines and their in vitro and in vivo binding properties in rodent and monkey brains.
Biological & pharmaceutical bulletin 2004;27(4):531-7.
2004: Shigeki Sasaki; Yosuke Taniguchi; Ryo Takahashi; Yusuke Senko; Keiichi Kodama; Fumi Nagatsugi; Minoru Maeda
Selective formation of stable triplexes including a TA or a CG interrupting site with new bicyclic nucleoside analogues (WNA).
Journal of the American Chemical Society 2004;126(2):516-28.
2003: Takeshi Fuchigami; Terushi Haradahira; Takuya Arai; Takashi Okauchi; Jun Maeda; Kazutoshi Suzuki; Fumihiko Yamamoto; Tetsuya Suhara; Shigeki Sasaki; Minoru Maeda
Synthesis and brain regional distribution of [11C]NPS 1506 in mice and rat: an N-methyl-D-aspartate (NMDA) receptor antagonist.
Biological & pharmaceutical bulletin 2003;26(11):1570-3.
2003: Akira Ohgushi; Naoya Wasano; Noriko Shisa; Hiroyuki Saitoh; Eiichi Mizuki; Minoru Maeda; Michio Ohba
Characterization of a mosquitocidal Bacillus thuringiensis serovar sotto strain isolated from Okinawa, Japan.
Journal of applied microbiology 2003;95(5):982-9.
2002: Fumihiko Yamamoto; Mizuho Aoki; Yoshiya Furusawa; Koichi Ando; Yasuo Kuwabara; Kouji Masuda; Shigeki Sasaki; Minoru Maeda
Synthesis and evaluation of 4-bromo-1-(3-[18F]fluoropropyl)-2-nitroimidazole with a low energy LUMO orbital designed as brain hypoxia-targeting imaging agent.
Biological & pharmaceutical bulletin 2002;25(5):616-21.
2002: Fumi Nagatsugi; Yoshihisa Matsuyama; Minoru Maeda; Shigeki Sasaki
Selective cross-linking to the adenine of the TA interrupting site within the triple helix.
Bioorganic & medicinal chemistry letters 2002;12(3):487-9.
2002: Md Monsur Ali; Fumi Nagatsugi; Fumihiko Yamamoto; Minoru Maeda; Shigeki Sasaki
2-Amino-6-vinyl purine as a tool for post synthetic conjugation of DNA with radio-, spin-, fluorescence labels and peptides.
Nucleic acids research. Supplement (2001) 2002;(2):149-50.
2002: Yosuke Taniguchi; Ryo Takahashi; Keiichi Kodama; Yusuke Senko; Minoru Maeda; Shigeki Sasaki
Selective formation of non-natural type triplexes containing TA interrupting sites with the TFO incorporating W-shape nucleic acid (WNA) analogs.
Nucleic acids research. Supplement (2001) 2002;(2):35-6.
2001: Shigeki Sasaki; T Ehara; Mohammed Alam; Y Fujino; N Harada; J Kimura; H Nakamura; Minoru Maeda
Solid-Phase synthesis of a library constructed of aromatic phosphate, long alkyl chains and tryptophane components, and identification of potent dipeptide telomerase inhibitors.
Bioorganic & medicinal chemistry letters 2001;11(19):2581-4.
2001: Fumi Nagatsugi; N Tokuda; Minoru Maeda; Shigeki Sasaki
A new reactive nucleoside analogue for highly reactive and selective cross-linking reaction to cytidine under neutral conditions.
Bioorganic & medicinal chemistry letters 2001;11(19):2577-9.
2001: Fumi Nagatsugi; Takeshi Kawasaki; N Tokuda; Minoru Maeda; Shigeki Sasaki
Site-directed alkylation to cytidine within duplex by the oligonucleotides containing functional nucleobases.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):915-9.
2001: Shigeki Sasaki; T Shibata; H Torigoe; Y Shibata; Minoru Maeda
Novel class of DNA binding motifs based on bistetrahydrofuran and bisfuran skeleton with long alkyl chains.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):551-8.
2001: Masaharu Murata; M Nakayama; H Irie; K Yakabe; K Fukuma; Yoshiki Katayama; Minoru Maeda
Novel biosensor for the rapid measurement of estrogen based on a ligand-receptor interaction.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 2001;17(3):387-90.
2001: Shigeki Sasaki; T Ehara; I Sakata; Y Fujino; N Harada; J Kimura; H Nakamura; Minoru Maeda
Development of novel telomerase inhibitors based on a bisindole unit.
Bioorganic & medicinal chemistry letters 2001;11(4):583-5.
2001: Shigeki Sasaki; T Kanda; N Ishibashi; Fumihiko Yamamoto; Terushi Haradahira; Takashi Okauchi; J Meda; K Suzuki; Minoru Maeda
4,5,9,10-Tetrahydro-1,4-ethanobenz[b]quinolizine as a prodrug for its quinolizinium cation as a ligand to the open state of the TCP-binding site of NMDA receptors.
Bioorganic & medicinal chemistry letters 2001;11(4):519-21.
2001: Fumi Nagatsugi; D Usui; Takeshi Kawasaki; Minoru Maeda; Shigeki Sasaki
Selective reaction to a flipping cytidine of the duplex DNA mediated by triple helix formation.
Bioorganic & medicinal chemistry letters 2001;11(3):343-5.
2001: T Mori; Daisuke Umeno; Minoru Maeda
Sequence-specific affinity precipitation of oligonucleotide using poly(N-isopropylacrylamide)-oligonucleotide conjugate.
Biotechnology and bioengineering 2001;72(3):261-8.
2001: Z Tang; Takeshi Mori; Tohru Takarada; Minoru Maeda
Single nucleotide polymorphisms (SNPs) assay using reversible association and dispersion of DNA-linked colloidal nanoparticles.
Nucleic acids research. Supplement (2001) 2001;(1):165-6.
2001: Shigeki Sakakihara; K Fujii; Yoshiki Katayama; Minoru Maeda
A novel regulation system of gene expression responding to protease signal.
Nucleic acids research. Supplement (2001) 2001;(1):149-50.
2001: Fumi Nagatsugi; N Tokuda; Takeshi Kawasaki; Minoru Maeda; Shigeki Sasaki
Efficient cross-linking to cytidine under neutral conditions using the 2-amino-6-vinylpurine derivative having an additional activating group.
Nucleic acids research. Supplement (2001) 2001;(1):87-8.
2001: Shigeki Sasaki; H Yamauchi; R Takahasi; Yosuke Taniguchi; Minoru Maeda
New base analogs for the formation of non-natural triplexes.
Nucleic acids research. Supplement (2001) 2001;(1):23-4.
2001: Yoshiki Katayama; Shigeki Sakakihara; Minoru Maeda
Electrochemical sensing for the determination of activated cyclic AMP-dependent protein kinase.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 2001;17(1):17-9.
2000: Mohammed Alam; Minoru Maeda; Shigeki Sasaki
DNA-binding peptides searched from the solid-phase combinatorial library with the use of the magnetic beads attaching the target duplex DNA.
Bioorganic & medicinal chemistry 2000;8(2):465-73.
2000: Takeshi Kawasaki; Fumi Nagatsugi; Minoru Maeda; Shigeki Sasaki
Efficient cross-linking to cytidine using substituted phenylsulfide derivatives of 2-amino-6-vinylpurine nucleoside via synchronous activation within duplex.
Nucleic acids symposium series 2000;(44):129-30.
2000: Fumi Nagatsugi; D Usui; Takeshi Kawasaki; Minoru Maeda; Shigeki Sasaki
Design and synthesis of the novel cross-linking reagents triggered by the triple helix formation.
Nucleic acids symposium series 2000;(44):39-40.
1999: Fumihiko Yamamoto; H Oka; S Antoku; Y Ichiya; Kouji Masuda; Minoru Maeda
Synthesis and characterization of lipophilic 1-[18F]fluoroalkyl-2-nitroimidazoles for imaging hypoxia.
Biological & pharmaceutical bulletin 1999;22(6):590-7.
1999: T Shibata; H Torigoe; Y Shibata; Minoru Maeda; Shigeki Sasaki
Novel DNA-binding ligands with sequence selectivity based on hydrophobic structure.
Nucleic acids symposium series 1999;(42):251-2.
1999: Mohammed Alam; Minoru Maeda; Shigeki Sasaki
DNA binding affinity of pentapeptides selected from combinatorial library.
Nucleic acids symposium series 1999;(42):173-4.
1999: T Mori; F Oda; Daisuke Umeno; Masaharu Murata; Minoru Maeda
Affinity separation of messenger RNA by thermo-responsive polymer carrying oligo(dT).
Nucleic acids symposium series 1999;(42):55-6.
1999: Takeshi Kawasaki; Fumi Nagatsugi; D Usui; Minoru Maeda; Shigeki Sasaki
Efficient cross-linking to cytidine by functional nucleobases capable of in situ activation.
Nucleic acids symposium series 1999;(42):43-4.
1998: Shigeki Sasaki; N Ishibashi; T Kuwamura; H Sano; M Matoba; T Nisikawa; Minoru Maeda
Excellent acceleration of the Diels-Alder reaction by microwave irradiation for the synthesis of new fluorine-substituted ligands of NMDA receptor.
Bioorganic & medicinal chemistry letters 1998;8(21):2983-6.
1998: Daisuke Umeno; M Kawasaki; Minoru Maeda
Water-soluble conjugate of double-stranded DNA and Poly(N-isopropylacrylamide) for one-pot affinity precipitation separation of DNA-binding proteins.
Bioconjugate chemistry 1998;9(6):719-24.
1998: Shigeki Sasaki; T Hashimoto; N Obana; H Yasuda; Y Uehara; Minoru Maeda
Design of new inhibitors for cdc2 kinase based on a multiple pseudosubstrate structure.
Bioorganic & medicinal chemistry letters 1998;8(9):1019-22.
1998: Shigeki Sasaki; K Maruta; H Naito; R Maemura; E Kawahara; Minoru Maeda
In vitro antitumor activities of new synthetic bistetrahydrofuran derivatives as analogs of Annonaceous acetogenins.
Chemical & pharmaceutical bulletin 1998;46(1):154-8.
1997: Y Ozaki; T Ihara; Y Katayama; Minoru Maeda
Affinity capillary electrophoresis using DNA conjugates.
Nucleic acids symposium series 1997;(37):235-6.
1997: Fumi Nagatsugi; Takeshi Kawasaki; Minoru Maeda; Shigeki Sasaki
Novel cross-linking reaction of oligonucleotides incorporating new base analogs with selective reactivity toward cytidine.
Nucleic acids symposium series 1997;(37):67-8.
1997: S Nakashima; N Matsuura; Fumi Nagatsugi; Minoru Maeda; Shigeki Sasaki
Synthesis and evaluation of oligonucleotides incorporating novel artificial nucleobases for the selective formation of non-natural type triplexes.
Nucleic acids symposium series 1997;(37):33-4.
1996: F Yamamoto; S Shibata; S Watanabe; K Masuda; Minoru Maeda
Positron-labeled antioxidant 6-deoxy-6-[18F]fluoro-L-ascorbic acid: increased uptake in transient global ischemic rat brain.
Nuclear medicine and biology 1996;23(4):479-86.
1995: Fumi Nagatsugi; F Inoue; Shigeki Sasaki; Minoru Maeda
18F-labeled octanoates as potential agents for cerebral fatty acid studies. The influence of 4-substitution and the fluorine position on biodistribution.
Chemical & pharmaceutical bulletin 1995;43(4):607-15.
1995: Fumi Nagatsugi; K Uemura; S Nakashima; Minoru Maeda; Shigeki Sasaki
Design and synthesis of new cross-linking agents.
Nucleic acids symposium series 1995;(34):171-2.
1994: Minoru Maeda; C Nishimura; Daisuke Umeno; M Takagi
Psoralen-containing vinyl monomer for conjugation of double-helical DNA with vinyl polymers.
Bioconjugate chemistry 1994;5(6):527-31.
1994: Fumi Nagatsugi; Shigeki Sasaki; Minoru Maeda
8-[18F]fluorooctanoic acid and its beta-substituted derivatives as potential agents for cerebral fatty acid studies: synthesis and biodistribution.
Nuclear medicine and biology 1994;21(6):809-17.
1994: T Haradahira; Minoru Maeda; A Kato; Y Kanazawa; M Yamada; Y Torii; Y Ichiya; K Masuda
Metabolic pathway of 2-deoxy-2-[18F]fluoro-D-talose in mice: trapping in tissue after phosphorylation by galactokinase.
Nuclear medicine and biology 1994;21(2):269-76.
1993: K Orita; Shigeki Sasaki; Minoru Maeda; A Hashimoto; T Nishikawa; T Yugami; K Umezu
Synthesis and evaluation of 1-(1-[5-(2'-[18F]fluoroethyl)-2-thienyl]-cyclohexyl)piperidine as a potential in vivo radioligand for the NMDA receptor-channel complex.
Nuclear medicine and biology 1993;20(7):865-73.
1993: Shigeki Sasaki; F Takao; K Watanabe; N Obana; Minoru Maeda; T Fukumura; S Takehara
New fluorinated dopamine D2 ligands with benzofuran skeleton. The synthesis and in vitro evaluation.
Chemical & pharmaceutical bulletin 1993;41(2):296-300.
1992: Minoru Maeda; Shigeki Sasaki; T Fukumura; E Fukuzawa; K Watanabe; M Kojima; T Tahara; K Masuda; Y Ichiya
Positron-emitting N-[18F]fluoroalkyl and [18F]fluoropyrrolidinyl analogues of eticlopride as potential in vivo radioligands for dopamine D2 receptors.
Chemical & pharmaceutical bulletin 1992;40(7):1793-8.
1992: F Yamamoto; Shigeki Sasaki; Minoru Maeda
Positron labeled antioxidants: synthesis and tissue biodistribution of 6-deoxy-6-[18F]fluoro-L-ascorbic acid.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1992;43(5):633-9.
1992: T Haradahira; A Kato; Minoru Maeda; Y Torii; Y Ichiya; K Masuda
Synthesis and biodistribution of a fluorine-18 labeled analogue of D-talose: 2-deoxy-2-[18F]fluoro-D-talose.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1992;43(5):627-32.
1991: K Watanabe; T Fukumura; Shigeki Sasaki; Minoru Maeda; S Takehara
New fluorine-substituted analogue of eticlopride with high affinity toward dopamine D2 receptors.
Chemical & pharmaceutical bulletin 1991;39(12):3211-4.
1991: S Tsukiyama; A Hashimoto; S Katayama; T Nishikawa; A Tobe; Minoru Maeda
Fluoromethylated and hydroxymethylated derivatives of N-methyl-D-aspartate receptor antagonist 1-[1-(2-thienyl)cyclohexyl]piperidine.
Chemical & pharmaceutical bulletin 1991;39(6):1581-4.
1990: T Fukumura; H Dohmoto; Minoru Maeda; E Fukuzawa; M Kojima
Synthesis and in vitro affinity for dopamine D-2 receptor of N-fluorine-substituted analogs of eticlopride.
Chemical & pharmaceutical bulletin 1990;38(6):1740-2.
1990: Minoru Maeda; Y Koga; T Fukumura; M Kojima
[11C]octopamine synthesis using [11C]cyanide: chemical and enzymatic approaches for the [11C]cyanohydrin synthesis.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1990;41(5):463-9.