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Nobuyo Maeda

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John M S Wait; Otto Z Zhou; Laurel M Burk; Jianping Lu; Nobuyo Maeda; Hirofumi Tomita; Yueh Z Lee
Detection of aortic arch calcification in apolipoprotein E-null mice using carbon nanotube-based micro-CT system.
Lance A Johnson; Hyung-Suk Kim; Melissa J Knudson; C Taylor Nipp; Xianwen Yi; Nobuyo Maeda
Diabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammation.
Xianwen Yi; Longquan Xu; Sylvia Hiller; Hyung-Suk Kim; Nobuyo Maeda
Reduced alpha-lipoic acid synthase gene expression exacerbates atherosclerosis in diabetic apolipoprotein E-deficient mice.

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2013: John M S Wait; Otto Z Zhou; Laurel M Burk; Jianping Lu; Nobuyo Maeda; Hirofumi Tomita; Yueh Z Lee
Detection of aortic arch calcification in apolipoprotein E-null mice using carbon nanotube-based micro-CT system.
Journal of the American Heart Association 2013;2(1):e003358.
2013: Lance A Johnson; Hyung-Suk Kim; Melissa J Knudson; C Taylor Nipp; Xianwen Yi; Nobuyo Maeda
Diabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammation.
Journal of lipid research 2013;54(2):386-96.
2012: Xianwen Yi; Longquan Xu; Sylvia Hiller; Hyung-Suk Kim; Nobuyo Maeda
Reduced alpha-lipoic acid synthase gene expression exacerbates atherosclerosis in diabetic apolipoprotein E-deficient mice.
Atherosclerosis 2012;223(1):137-43.
2012: Avani A Pendse; Carolyn Wilhelm; Lance A Johnson; Hyung-Suk Kim; Marcus McNair; C Taylor Nipp; Nobuyo Maeda
Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(6):1436-44.
2012: Raymond G Fox; Gregory C Kujoth; Scott T Magness; Tomas A Prolla; Nobuyo Maeda
Mitochondrial DNA polymerase editing mutation, PolgD257A, disturbs stem-progenitor cell cycling in the small intestine and restricts excess fat absorption.
American journal of physiology. Gastrointestinal and liver physiology 2012;302(9):G914-24.
2011: Soonkyu Chung; Abraham K Gebre; Nobuyo Maeda; Janet K Sawyer; John S Parks
Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo.
Circulation 2011;124(15):1663-72.
2011: Nobuyo Maeda
Development of apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(9):1957-62.
2011: Zhi Hua Huang; Nobuyo Maeda; Theodore Mazzone
Expression of the human apoE2 isoform in adipocytes: altered cellular processing and impaired adipocyte lipogenesis.
Journal of lipid research 2011;52(9):1733-41.
2011: Raymond Fox; Hyung-Suk Kim; Robert L Reddick; Gregory C Kujoth; Tomas A Prolla; Shuichi Tsutsumi; Youichiro Wada; Oliver Smithies; Nobuyo Maeda
Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):8779-84.
2011: Xianwen Yi; Volker Nickeleit; Leighton R James; Nobuyo Maeda
α-Lipoic acid protects diabetic apolipoprotein E-deficient mice from nephropathy.
Journal of diabetes and its complications 2011;25(3):193-201.
2011: Chih-Hong Wang; Feng Li; S Hiller; Hyung-Suk Kim; Nobuyo Maeda; Oliver Smithies; Nobuyuki Takahashi
A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(5):2070-5.
2010: Vijay Kandalam; Ratnadeep Basu; Thomas Abraham; Xiuhua Wang; Ahmed Awad; Wei Wang; Gary D Lopaschuk; Nobuyo Maeda; Gavin Y Oudit; Zamaneh Kassiri
Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2010;299(4):H1012-23.
2010: F Li; C-H Wang; J-G Wang; T Thai; G Boysen; Lingfei Xu; A L Turner; Alisa S Wolberg; Nigel Mackman; Nobuyo Maeda; N Takahashi
Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet.
Journal of thrombosis and haemostasis : JTH 2010;8(10):2122-32.
2010: Jose M Arbones-Mainar; Lance A Johnson; Michael K Altenburg; Hyung-Suk Kim; Nobuyo Maeda
Impaired adipogenic response to thiazolidinediones in mice expressing human apolipoproteinE4.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(10):3809-18.
2010: Xianwen Yi; Longquan Xu; Kuikwon Kim; Hyung-Suk Kim; Nobuyo Maeda
Genetic reduction of lipoic acid synthase expression modestly increases atherosclerosis in male, but not in female, apolipoprotein E-deficient mice.
Atherosclerosis 2010;211(2):424-30.
2010: Soonkyu Chung; Jenelle M Timmins; MyNgan Duong; Chiara Degirolamo; Shunxing Rong; Janet K Sawyer; Roshni R Singaraja; Michael R Hayden; Nobuyo Maeda; Lawrence L Rudel; Gregory S Shelness; John S Parks
Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism.
The Journal of biological chemistry 2010;285(16):12197-209.
2010: Hirofumi Tomita; Svetlana Zhilicheva; Shinja Kim; Nobuyo Maeda
Aortic arch curvature and atherosclerosis have overlapping quantitative trait loci in a cross between 129S6/SvEvTac and C57BL/6J apolipoprotein E-null mice.
Circulation research 2010;106(6):1052-60.
2010: Henry L Keen; Carmen M Halabi; andreas beyer; Willem J de Lange; Xuebo Liu; Nobuyo Maeda; Frank M Faraci; Thomas L Casavant; Curt D Sigmund
Bioinformatic analysis of gene sets regulated by ligand-activated and dominant-negative peroxisome proliferator-activated receptor gamma in mouse aorta.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(3):518-25.
2010: Heather E Doherty; Hyung-Suk Kim; Sylvia Hiller; Kathleen K Sulik; Nobuyo Maeda
A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high.
PloS one 2010;5(9):e12909.
2009: Hui Zhu; Ji Zhang; Jessica Shih; Federico Lopez-Bertoni; John R Hagaman; Nobuyo Maeda; Morton H Friedman
Differences in aortic arch geometry, hemodynamics, and plaque patterns between C57BL/6 and 129/SvEv mice.
Journal of biomechanical engineering 2009;131(12):121005.
2009: Nicola J A Scott; Leigh J Ellmers; John G Lainchbury; Nobuyo Maeda; Oliver Smithies; A Mark Richards; Vicky A Cameron
Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.
Biochimica et biophysica acta 2009;1792(12):1175-84.
2009: Yau-Sheng Tsai; Lonquan Xu; Oliver Smithies; Nobuyo Maeda
Genetic variations in peroxisome proliferator-activated receptor gamma expression affect blood pressure.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(45):19084-9.
2009: Yau-Sheng Tsai; Pei-Jane Tsai; Man-Jin Jiang; Ting-Yu Chou; Avani Pendse; Hyung-Suk Kim; Nobuyo Maeda
Decreased PPAR gamma expression compromises perigonadal-specific fat deposition and insulin sensitivity.
Molecular endocrinology (Baltimore, Md.) 2009;23(11):1787-98.
2009: Zamaneh Kassiri; Gavin Y Oudit; Vijay Kandalam; Ahmed Awad; Xiuhua Wang; Xiuhua Ziou; Nobuyo Maeda; Andrew M Herzenberg; James W Scholey
Loss of TIMP3 enhances interstitial nephritis and fibrosis.
Journal of the American Society of Nephrology : JASN 2009;20(6):1223-35.
2009: Toshio Nishikimi; Chikako Inaba-Iemura; Kimihiko Ishimura; Kazuyoshi Tadokoro; Shogo Koshikawa; Keiko Ishikawa; Kazumi Akimoto; Yoshiyuki Hattori; Kikuo Kasai; Naoto Minamino; Nobuyo Maeda; Hiroaki Matsuoka
Natriuretic peptide/natriuretic peptide receptor-A (NPR-A) system has inhibitory effects in renal fibrosis in mice.
Regulatory peptides 2009;154(1-3):44-53.
2009: Dane Meredith; Manikandan Panchatcharam; Sumitra Miriyala; Yau-Sheng Tsai; Andrew J Morris; Nobuyo Maeda; George A Stouffer; Susan Smyth
Dominant-negative loss of PPARgamma function enhances smooth muscle cell proliferation, migration, and vascular remodeling.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(4):465-71.
2009: Avani A Pendse; Jose M Arbones-Mainar; Lance A Johnson; Michael K Altenburg; Nobuyo Maeda
Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond.
Journal of lipid research 2009;50 Suppl():S178-82.
2009: Jui-Sheng Wu; Wai-Mui Cheung; Yau-Sheng Tsai; Yi-Tong Chen; Wen-Hsuan Fong; Hsin-Da Tsai; Yu-Chang Chen; Jun-Yang Liou; Song-Kun Shyue; Jin-Jer Chen; Y Eugene Chen; Nobuyo Maeda; Kenneth K Wu; Teng-nan Lin
Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation.
Circulation 2009;119(8):1124-34.
2009: N Franceschini; H Muallem; Kathryn M Rose; E Boerwinkle; Nobuyo Maeda
Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study.
Journal of thrombosis and haemostasis : JTH 2009;7(3):496-8.
2009: Saovaros Svasti; Thipparat Suwanmanee; Suthat Fucharoen; Hong M Moulton; Michelle H Nelson; Nobuyo Maeda; Oliver Smithies; Ryszard Kole
RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1205-10.
2009: Xianwen Yi; Kuikwon Kim; Weiping Yuan; Longquan Xu; Hyung-Suk Kim; Jonathon W Homeister; Nigel S Key; Nobuyo Maeda
Mice with heterozygous deficiency of lipoic acid synthase have an increased sensitivity to lipopolysaccharide-induced tissue injury.
Journal of leukocyte biology 2009;85(1):146-53.
2008: J M Arbones-Mainar; L A Johnson; mike altenburg; Nobuyo Maeda
Differential modulation of diet-induced obesity and adipocyte functionality by human apolipoprotein E3 and E4 in mice.
International journal of obesity (2005) 2008;32(10):1595-605.
2008: Lance A Johnson; mike altenburg; Rosemary Walzem; Lori T Scanga; Nobuyo Maeda
Absence of hyperlipidemia in LDL receptor-deficient mice having apolipoprotein B100 without the putative receptor-binding sequences.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(10):1745-52.
2008: Kumar Pandya; John Cowhig; Joe Brackhan; Hyung-Suk Kim; John R Hagaman; Mauricio Rojas; Charles Carter; Lan Mao; Howard A Rockman; Nobuyo Maeda; Oliver Smithies
Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):13063-8.
2008: Eliana Polisecki; Hind Muallem; Nobuyo Maeda; Inga Peter; Michele Robertson; Alex D McMahon; Ian Ford; Christopher Packard; James Shepherd; J Wouter Jukema; Rudi G J Westendorp; Anton J M de Craen; Brendan M Buckley; Jose Ordovas; Ernst Schaefer
Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.
Atherosclerosis 2008;200(1):109-14.
2008: Xuewei Zhu; Ji-Young Lee; Jenelle M Timmins; J Mark Brown; Elena Boudyguina; Anny Mulya; Abraham K Gebre; Mark C Willingham; Elizabeth M Hiltbold; Nilamadhab Mishra; Nobuyo Maeda; John S Parks
Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages.
The Journal of biological chemistry 2008;283(34):22930-41.
2008: Kristiaan Wouters; Patrick van Gorp; Veerle Bieghs; Marion J Gijbels; Hans Duimel; Dieter Lütjohann; Anja Kerksiek; Roger van Kruchten; Nobuyo Maeda; Bart Staels; Marc van Bilsen; Ronit Shiri-Sverdlov; Marten H Hofker
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis.
Hepatology (Baltimore, Md.) 2008;48(2):474-86.
2008: Yunhao Liu; Daniel Timothy Sweet; Mohamad Irani-Tehrani; Nobuyo Maeda; Eleni Tzima
Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation.
The Journal of cell biology 2008;182(1):185-96.
2008: Gültekin Tamgüney; Kurt Giles; David V Glidden; Pierre Lessard; Holger Wille; Patrick Tremblay; Darlene F Groth; Fruma Yehiely; Carsten Korth; Richard C Moore; Jörg Tatzelt; Eric Rubinstein; Claude Boucheix; Xiaoping Yang; Pamela Stanley; Michael P Lisanti; Raymond A Dwek; Pauline M Rudd; Jackob Moskovitz; Charles J Epstein; Tracey Dawson Cruz; William Kuziel; Nobuyo Maeda; Jan Sap; Karen K. Hsiao Ashe; George A Carlson; Ina C. Tesseur; Tony Wyss-Coray; Lennart Mucke; Karl H Weisgraber; Robert W Mahley; Fred Cohen; Stanley B Prusiner
Genes contributing to prion pathogenesis.
The Journal of general virology 2008;89(Pt 7):1777-88.
2008: mike altenburg; Jose Arbones-Mainar; Lance Johnson; Jennifer Wilder; Nobuyo Maeda
Human LDL receptor enhances sequestration of ApoE4 and VLDL remnants on the surface of hepatocytes but not their internalization in mice.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(6):1104-10.
2008: K Bridget Brosnihan; Jeffrey B Hodgin; Oliver Smithies; Nobuyo Maeda; Patricia Gallagher
Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice.
Experimental physiology 2008;93(5):658-64.
2008: andreas beyer; Gary L Baumbach; Carmen M Halabi; Mary L Modrick; Cynthia M Lynch; Thomas D Gerhold; Shams M Ghoneim; Willem J de Lange; Henry L Keen; Yau-Sheng Tsai; Nobuyo Maeda; Curt D Sigmund; Frank M Faraci
Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling.
Hypertension 2008;51(4):867-71.
2007: mike altenburg; Jonathon W Homeister; Heather Doherty; Nobuyo Maeda
Genetics of atherosclerosis in murine models.
Current drug targets 2007;8(11):1161-71.
2007: Rita K Upmacis; Mark Crabtree; Ruba S Deeb; Hao Shen; Paul B Lane; Lea Esther S Benguigui; Nobuyo Maeda; David P Hajjar; Steven S Gross
Profound biopterin oxidation and protein tyrosine nitration in tissues of ApoE-null mice on an atherogenic diet: contribution of inducible nitric oxide synthase.
American journal of physiology. Heart and circulatory physiology 2007;293(5):H2878-87.
2007: Nobuyo Maeda; Lance Johnson; Shinja Kim; John R Hagaman; Morton Friedman; Robert L Reddick
Anatomical differences and atherosclerosis in apolipoprotein E-deficient mice with 129/SvEv and C57BL/6 genetic backgrounds.
Atherosclerosis 2007;195(1):75-82.
2007: Barbara P Atshaves; Avery L McIntosh; H Ross Payne; Adalberto M Gallegos; Kerstin K Landrock; Nobuyo Maeda; Ann B Kier; Friedhelm Schroeder
SCP-2/SCP-x gene ablation alters lipid raft domains in primary cultured mouse hepatocytes.
Journal of lipid research 2007;48(10):2193-211.
2007: Willa Hsueh; E Dale Abel; Jan L Breslow; Nobuyo Maeda; Richard C Davis; Edward A Fisher; Hayes M Dansky; Donald A McClain; McIndoe Richard; Momtaz K Wassef; Cristina Rabadán-Diehl; Ira J Goldberg
Recipes for creating animal models of diabetic cardiovascular disease.
Circulation research 2007;100(10):1415-27.
2007: Hind Muallem; Kari E North; Masao Kakoki; Mary K Wojczynski; Xia Li; Megan Grove; Eric Boerwinkle; Kirk Wilhelmsen; Gerardo Heiss; Nobuyo Maeda
Quantitative effects of common genetic variations in the 3'UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study.
Human genetics 2007;121(3-4):421-31.
2007: mike altenburg; Lance Johnson; Jennifer Wilder; Nobuyo Maeda
Apolipoprotein E4 in macrophages enhances atherogenesis in a low density lipoprotein receptor-dependent manner.
The Journal of biological chemistry 2007;282(11):7817-24.
2007: Barbara P Atshaves; Avery L McIntosh; Danilo Landrock; H Ross Payne; John T Mackie; Nobuyo Maeda; Judith Ball; Friedhelm Schroeder; Ann B Kier
Effect of SCP-x gene ablation on branched-chain fatty acid metabolism.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(3):G939-51.
2007: Leigh J Ellmers; Nicola J A Scott; Jarkko Piuhola; Nobuyo Maeda; Oliver Smithies; Christopher M Frampton; A Mark Richards; Vicky A Cameron
Npr1-regulated gene pathways contributing to cardiac hypertrophy and fibrosis.
Journal of molecular endocrinology 2007;38(1-2):245-57.
2007: Danijela Lucic; Zhi Hua Huang; De Sheng Gu; mike altenburg; Nobuyo Maeda; Theodore Mazzone
Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor.
Journal of lipid research 2007;48(2):366-72.
2007: Christopher Jones; Rita Garuti; Peter Michaely; Wei-Ping Li; Nobuyo Maeda; Jonathan C Cohen; Joachim Herz; Helen H Hobbs
Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia.
The Journal of clinical investigation 2007;117(1):165-74.
2006: Weiping Yuan; Tina M Leisner; Andrew W McFadden; Shantres Clark; Sylvia Hiller; Nobuyo Maeda; Deborah A O'Brien; Leslie V Parise
CIB1 is essential for mouse spermatogenesis.
Molecular and cellular biology 2006;26(22):8507-14.
2006: Wei Li; Nobuyo Maeda; Melinda A Beck
Vitamin C deficiency increases the lung pathology of influenza virus-infected gulo-/- mice.
The Journal of nutrition 2006;136(10):2611-6.
2006: Xianwen Yi; Nobuyo Maeda
alpha-Lipoic acid prevents the increase in atherosclerosis induced by diabetes in apolipoprotein E-deficient mice fed high-fat/low-cholesterol diet.
Diabetes 2006;55(8):2238-44.
2006: Masao Kakoki; Hyung-Suk Kim; Cora-Jean S Edgell; Nobuyo Maeda; Oliver Smithies; David L Mattson
Amino acids as modulators of endothelium-derived nitric oxide.
American journal of physiology. Renal physiology 2006;291(2):F297-304.
2006: Yau-Sheng Tsai; Avani Pendse; Sheryl S Moy; Ikuko Mohri; Antonio Perez; Jacqueline N Crawley; Kinuko Suzuki; Nobuyo Maeda
A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene.
Mammalian genome : official journal of the International Mammalian Genome Society 2006;17(7):716-22.
2006: Futoshi Yazama; Kazuko Furuta; Miwa Fujimoto; Tomoko Sonoda; Hiroko Shigetomi; Toshitaka Horiuchi; Manabu Yamada; Norio Nagao; Nobuyo Maeda
Abnormal spermatogenesis in mice unable to synthesize ascorbic acid.
Anatomical science international 2006;81(2):115-25.
2006: Andrei L Kindzelskii; Andrea J Clark; Jimmy Espinoza; Nobuyo Maeda; Yasuaki Aratani; Roberto Romero; Howard R Petty
Myeloperoxidase accumulates at the neutrophil surface and enhances cell metabolism and oxidant release during pregnancy.
European journal of immunology 2006;36(6):1619-28.
2006: Kelly K Parsons; Nobuyo Maeda; Mitsuo Yamauchi; Albert J Banes; Beverly H Koller
Ascorbic acid-independent synthesis of collagen in mice.
American journal of physiology. Endocrinology and metabolism 2006;290(6):E1131-9.
2006: J Komatsu; H Koyama; Nobuyo Maeda; Yasuaki Aratani
Earlier onset of neutrophil-mediated inflammation in the ultraviolet-exposed skin of mice deficient in myeloperoxidase and NADPH oxidase.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2006;55(5):200-6.
2006: Joseph P Gaut; Azzaq Belaaouaj; Jaeman Byun; L Jackson Roberts; Nobuyo Maeda; Balz Frei; Jay W Heinecke
Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation.
Free radical biology & medicine 2006;40(9):1494-501.
2006: Masao Kakoki; Catherine M Kizer; Xianwen Yi; Nobuyuki Takahashi; Hyung-Suk Kim; Charles Bagnell; Cora-Jean S Edgell; Nobuyo Maeda; John Jennette; Oliver Smithies
Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors.
The Journal of clinical investigation 2006;116(5):1302-9.
2006: Hafid Mezdour; Guilhem Larigauderie; Graciela Castro; Gérard Torpier; Jamila Fruchart; Maxime NOWAK; Jean-Charles Fruchart; Mustapha Rouis; Nobuyo Maeda
Characterization of a new mouse model for human apolipoprotein A-I/C-III/A-IV deficiency.
Journal of lipid research 2006;47(5):912-20.
2006: Yoshiyuki Adachi; Andrei L Kindzelskii; Aaron R Petty; Ji-Biao Huang; Nobuyo Maeda; Satoshi Yotsumoto; Yasuaki Aratani; Naohito Ohno; Howard R Petty
IFN-gamma primes RAW264 macrophages and human monocytes for enhanced oxidant production in response to CpG DNA via metabolic signaling: roles of TLR9 and myeloperoxidase trafficking.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):5033-40.
2006: Ronit Shiri-Sverdlov; Kristiaan Wouters; Patrick van Gorp; Marion J J Gijbels; Benoit Noel; Laurent Buffat; Bart Staels; Nobuyo Maeda; Marc van Bilsen; Marten H Hofker
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates.
Journal of hepatology 2006;44(4):732-41.
2006: Toshio Nishikimi; Nobuyo Maeda; Hiroaki Matsuoka
The role of natriuretic peptides in cardioprotection.
Cardiovascular research 2006;69(2):318-28.
2006: Ruba S Deeb; Hao Shen; Caryn Gamss; Tatyana Gavrilova; Barbara D Summers; Rosemary Kraemer; Gang Hao; Steven S Gross; Muriel Lainé; Nobuyo Maeda; David P Hajjar; Rita K Upmacis
Inducible nitric oxide synthase mediates prostaglandin h2 synthase nitration and suppresses eicosanoid production.
The American journal of pathology 2006;168(1):349-62.
2005: John R Hagaman; Simon John; Lonquan Xu; Oliver Smithies; Nobuyo Maeda
An improved technique for tail-cuff blood pressure measurements with dark-tailed mice.
Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science 2005;44(5):43-6.
2005: Xianwen Yi; Nobuyo Maeda
Endogenous production of lipoic acid is essential for mouse development.
Molecular and cellular biology 2005;25(18):8387-92.
2005: Hong Xiao; Peter Heeringa; Zhi Liu; Dennis Huugen; Peiqi Hu; Nobuyo Maeda; Ronald J Falk; John Jennette
The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies.
The American journal of pathology 2005;167(1):39-45.
2005: Myron E Hinsdale; Nobuyo Maeda
Complex control of mouse apolipoprotein B gene expression revealed by targeted duplication.
Biochimica et biophysica acta 2005;1734(2):178-89.
2005: Jenelle M Timmins; Ji-Young Lee; Elena Boudyguina; Kimberly D Kluckman; Liam R Brunham; Anny Mulya; Abraham K Gebre; Jonathan M Coutinho; Perry L Colvin; Thomas L Smith; Michael R Hayden; Nobuyo Maeda; John S Parks
Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I.
The Journal of clinical investigation 2005;115(5):1333-42.
2005: Yau-Sheng Tsai; Nobuyo Maeda
PPARgamma: a critical determinant of body fat distribution in humans and mice.
Trends in cardiovascular medicine 2005;15(3):81-5.
2005: Toshio Nishikimi; John R Hagaman; Nobuyuki Takahashi; Hyung-Suk Kim; Hiroaki Matsuoka; Oliver Smithies; Nobuyo Maeda
Increased susceptibility to heart failure in response to volume overload in mice lacking natriuretic peptide receptor-A gene.
Cardiovascular research 2005;66(1):94-103.
2005: Chunsheng Wang; Wilkie A Wilson; Scott D Moore; Brian E Mace; Nobuyo Maeda; Donald E Schmechel; Patrick M. Sullivan
Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology.
Neurobiology of disease 2005;18(2):390-8.
2005: Sandrine Dubrac; Steven R Lear; Meenakshisundaram Ananthanarayanan; Natarajan Balasubramaniyan; Jaya Bollineni; Sarah Shefer; Hideyuki Hyogo; David E Cohen; Patricia J Blanche; Ronald M Krauss; Ashok K Batta; Gerald Salen; Frederick J Suchy; Nobuyo Maeda; Sandra K Erickson
Role of CYP27A in cholesterol and bile acid metabolism.
Journal of lipid research 2005;46(1):76-85.
2004: Christopher Knouff; Olivier Briand; Sophie Lestavel; Véronique Clavey; mike altenburg; Nobuyo Maeda
Defective VLDL metabolism and severe atherosclerosis in mice expressing human apolipoprotein E isoforms but lacking the LDL receptor.
Biochimica et biophysica acta 2004;1684(1-3):8-17.
2004: Yau-Sheng Tsai; Hyo-Jeong Kim; Nobuyuki Takahashi; Hyung-Suk Kim; John R Hagaman; Jason K Kim; Nobuyo Maeda
Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARgamma.
The Journal of clinical investigation 2004;114(2):240-9.
2004: Masao Kakoki; Yau-Sheng Tsai; Hyung-Suk Kim; Seigo Hatada; Dominic Ciavatta; Nobuyuki Takahashi; LW Arnold; Nobuyo Maeda; Oliver Smithies
Altering the expression in mice of genes by modifying their 3' regions.
Developmental cell 2004;6(4):597-606.
2004: Eric L Klett; Kangmo Lu; Astrid Kosters; Edwin Vink; Mi-Hye Lee; mike altenburg; Sarah Shefer; Ashok Batta; Hongwei Yu; Jianliang Chen; Richard L Klein; Norbert Looije; Ronald P J Oude Elferink; Albert K Groen; Nobuyo Maeda; Gerald Salen; Shailendra Patel
A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol.
BMC medicine 2004;2():5.
2004: James M Bates; Haja Mohideen Raffi; Krishna Prasadan; Ranjan Mascarenhas; Zoltan G Laszik; Nobuyo Maeda; Scott J Hultgren; Satish Kumar
Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication.
Kidney international 2004;65(3):791-7.
2004: Patrick M. Sullivan; Brian E Mace; Nobuyo Maeda; Donald E Schmechel
Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice.
Neuroscience 2004;124(4):725-33.
2004: Sudi I Malloy; mike altenburg; Christopher Knouff; Lorraine Lanningham-Foster; John S Parks; Nobuyo Maeda
Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):91-7.
2003: Seigo Hatada; Delores J Grant; Nobuyo Maeda
An intronic endogenous retrovirus-like sequence attenuates human haptoglobin-related gene expression in an orientation-dependent manner.
Gene 2003;319():55-63.
2003: Paul A Dawson; Jamie Haywood; Ann L Craddock; Martha Wilson; Mary Tietjen; Kimberly D Kluckman; Nobuyo Maeda; John S Parks
Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice.
The Journal of biological chemistry 2003;278(36):33920-7.
2003: Karine Robert; Jean-François Chassé; Dominique Santiard-Baron; Catherine Vayssettes; Allel Chabli; Joelle Aupetit; Nobuyo Maeda; Pierre Kamoun; Jacqueline London; Nathalie Janel
Altered gene expression in liver from a murine model of hyperhomocysteinemia.
The Journal of biological chemistry 2003;278(34):31504-11.
2003: Katsunori Jinnouchi; Yasuhiro Terasaki; Shigetoshi Fujiyama; Kimio Tomita; William Kuziel; Nobuyo Maeda; Kiyoshi Takahashi; Motohiro Takeya
Impaired hepatic granuloma formation in mice deficient in C-C chemokine receptor 2.
The Journal of pathology 2003;200(3):406-16.
2003: Matthew R Alexander; Joshua W Knowles; Toshio Nishikimi; Nobuyo Maeda
Increased atherosclerosis and smooth muscle cell hypertrophy in natriuretic peptide receptor A-/-apolipoprotein E-/- mice.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(6):1077-82.
2003: William Kuziel; Tracey C Dawson; Marlon P Quinones; Edgar Garavito; George Chenaux; Seema Ahuja; Robert L Reddick; Nobuyo Maeda
CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout mice.
Atherosclerosis 2003;167(1):25-32.
2003: Joshua W Knowles; Laurie M Erickson; Vanessa K Guy; Carlie S Sigel; Jennifer C Wilder; Nobuyo Maeda
Common variations in noncoding regions of the human natriuretic peptide receptor A gene have quantitative effects.
Human genetics 2003;112(1):62-70.
2002: Jeffrey B Hodgin; Nobuyo Maeda
Minireview: estrogen and mouse models of atherosclerosis.
Endocrinology 2002;143(12):4495-501.
2002: Linda E Hammond; Patricia Gallagher; Shuli Wang; Sylvia Hiller; Kimberly D Kluckman; Eugenia L Posey-Marcos; Nobuyo Maeda; Rosalind A Coleman
Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition.
Molecular and cellular biology 2002;22(23):8204-14.
2002: Michael R Adams; Deborah L Golden; Thomas C Register; Mary S Anthony; Jeffrey B Hodgin; Nobuyo Maeda; J Koudy Williams
The atheroprotective effect of dietary soy isoflavones in apolipoprotein E-/- mice requires the presence of estrogen receptor-alpha.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(11):1859-64.
2002: Hong Xiao; Peter Heeringa; Peiqi Hu; Zhi Liu; Ming-Lang Zhao; Yasuaki Aratani; Nobuyo Maeda; Ronald J Falk; John Jennette
Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice.
The Journal of clinical investigation 2002;110(7):955-63.
2002: Myron E Hinsdale; Patrick M. Sullivan; Hafid Mezdour; Nobuyo Maeda
ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice.
Journal of lipid research 2002;43(9):1520-8.
2002: Scott T Magness; Nobuyo Maeda; David A Brenner
An exon 10 deletion in the mouse ferrochelatase gene has a dominant-negative effect and causes mild protoporphyria.
Blood 2002;100(4):1470-7.
2002: Silvina F Choumenkovitch; Jacob Selhub; Pamela J Bagley; Nobuyo Maeda; Marie Nadeau; Donald E Smith; Sang-Woon Choi
In the cystathionine beta-synthase knockout mouse, elevations in total plasma homocysteine increase tissue S-adenosylhomocysteine, but responses of S-adenosylmethionine and DNA methylation are tissue specific.
The Journal of nutrition 2002;132(8):2157-60.
2002: Leigh J Ellmers; J W Knowles; H-S Kim; Oliver Smithies; Nobuyo Maeda; Vicky A Cameron
Ventricular expression of natriuretic peptides in Npr1(-/-) mice with cardiac hypertrophy and fibrosis.
American journal of physiology. Heart and circulatory physiology 2002;283(2):H707-14.
2002: Renu Garg; Paula M Oliver; Nobuyo Maeda; Kailash N Pandey
Genomic structure, organization, and promoter region analysis of murine guanylyl cyclase/atrial natriuretic peptide receptor-A gene.
Gene 2002;291(1-2):123-33.
2002: Malcolm A Lyons; Nobuyo Maeda; Andrew J Brown
Paradoxical enhancement of hepatic metabolism of 7-ketocholesterol in sterol 27-hydroxylase-deficient mice.
Biochimica et biophysica acta 2002;1581(3):119-26.
2002: Christine J Swardson-Olver; Tracey C Dawson; Robert C Burnett; Stephen Peiper; Nobuyo Maeda; Anne C Avery
Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion.
Blood 2002;99(8):2677-84.
2002: Hyung-Suk Kim; Gene Lee; Simon W M John; Nobuyo Maeda; Oliver Smithies
Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4602-7.
2002: Yukiko Nakata; Nobuyo Maeda
Vulnerable atherosclerotic plaque morphology in apolipoprotein E-deficient mice unable to make ascorbic Acid.
Circulation 2002;105(12):1485-90.
2002: Jiao-Hui Wu; John R Hagaman; Shinja Kim; Robert L Reddick; Nobuyo Maeda
Aortic constriction exacerbates atherosclerosis and induces cardiac dysfunction in mice lacking apolipoprotein E.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(3):469-75.
2002: Jeffrey B Hodgin; Joshua W Knowles; Hyung-Suk Kim; Oliver Smithies; Nobuyo Maeda
Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice.
The Journal of clinical investigation 2002;109(4):541-8.
2002: Seigo Hatada; John Seed; Chad Barker; Stephen L Hajduk; Samuel Black; Nobuyo Maeda
No trypanosome lytic activity in the sera of mice producing human haptoglobin-related protein.
Molecular and biochemical parasitology 2002;119(2):291-4.
2002: Shunya Takizawa; Yasuaki Aratani; Naoto Fukuyama; Nobuyo Maeda; Hisayuki Hirabayashi; Hideki Koyama; Yukito Shinohara; Hiroe Nakazawa
Deficiency of myeloperoxidase increases infarct volume and nitrotyrosine formation in mouse brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(1):50-4.
2002: Sirirak Chantakru; Craig Miller; Lindsay E Roach; William Kuziel; Nobuyo Maeda; Wan-Chao Wang; Sharon S Evans; B Anne Croy
Contributions from self-renewal and trafficking to the uterine NK cell population of early pregnancy.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):22-8.
2001: Akiko Ishida-Okawara; Toshiaki Oharaseki; Kei Takahashi; Y Hashimoto; Yasuaki Aratani; H Koyama; Nobuyo Maeda; Shiro Naoe; Kazuo Suzuki
Contribution of myeloperoxidase to coronary artery vasculitis associated with MPO-ANCA production.
Inflammation 2001;25(6):381-7.
2001: Osamu Yasuda; Keisuke Fukuo; Nobuyo Maeda; Toshio Ogihara
Elevated expression of type VIII collagen gene in the atherosclerotic plaque of the ApoE-deficient mouse.
Annals of the New York Academy of Sciences 2001;947():312-5.
2001: R C Gilmore; J Baker; S Dempsey; R Marchan; R N Corprew; G Byrd; Nobuyo Maeda; Oliver Smithies; Richard D Bukoski; Ken R Harewood; Pradeep K Chatterjee
Using PAC nested deletions to order contigs and microsatellite markers at the high repetitive sequence containing Npr3 gene locus.
Gene 2001;275(1):65-72.
2001: Barbara U Fitzky; Fabian F Moebius; H Asaoka; Heather G Waage-Baudet; L Xu; G Xu; Nobuyo Maeda; Kimberly D Kluckman; S Hiller; H Yu; Ashok K Batta; Sarah Shefer; T Chen; G Salen; Kathleen K Sulik; R D Simoni; G C Ness; Hartmut Glossmann; Shailendra Patel; Stephen G Tint
7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome.
The Journal of clinical investigation 2001;108(6):905-15.
2001: Michael F Goy; Paula M Oliver; K E Purdy; Joshua W Knowles; JE Fox; P J Mohler; X Qian; Oliver Smithies; Nobuyo Maeda
Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide.
The Biochemical journal 2001;358(Pt 2):379-87.
2001: Sanjana Dayal; Teodoro Bottiglieri; Erland Arning; Nobuyo Maeda; M Rene Malinow; Curt D Sigmund; Donald D Heistad; Frank M Faraci; Steven R Lentz
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Circulation research 2001;88(11):1203-9.
2001: Geoff Werstuck; Steven R Lentz; Sanjana Dayal; Gazi S Hossain; Sudesh K Sood; Y Y Shi; Ji Zhou; Nobuyo Maeda; S K Krisans; M Rene Malinow; Richard C Austin
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways.
The Journal of clinical investigation 2001;107(10):1263-73.
2001: Joshua W Knowles; G Esposito; L Mao; John R Hagaman; JE Fox; Oliver Smithies; Howard A Rockman; Nobuyo Maeda
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice.
The Journal of clinical investigation 2001;107(8):975-84.
2001: Christopher Knouff; S Malloy; J Wilder; mike altenburg; Nobuyo Maeda
Doubling expression of the low density lipoprotein receptor by truncation of the 3'-untranslated region sequence ameliorates type iii hyperlipoproteinemia in mice expressing the human apoe2 isoform.
The Journal of biological chemistry 2001;276(6):3856-62.
2001: Jeffrey B Hodgin; John Krege; Robert L Reddick; Kenneth S Korach; Oliver Smithies; Nobuyo Maeda
Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in Apoe-/- mice.
The Journal of clinical investigation 2001;107(3):333-40.
2001: Kelly A Hogan; Nobuyo Maeda; K D Kluckman; Susan T Lord
Synthesis of a mouse model of the dysfibrinogen Vlissingen/Frankfurt IV.
Annals of the New York Academy of Sciences 2001;936():117-21.
2001: Sirirak Chantakru; William Kuziel; Nobuyo Maeda; B Anne Croy
A study on the density and distribution of uterine Natural Killer cells at mid pregnancy in mice genetically-ablated for CCR2, CCR 5 and the CCR5 receptor ligand, MIP-1 alpha.
Journal of reproductive immunology 2001;49(1):33-47.
2000: Joshua W Knowles; Nobuyo Maeda
Genetic modifiers of atherosclerosis in mice.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(11):2336-45.
2000: Heike Siebert; A Sachse; William Kuziel; Nobuyo Maeda; Wolfgang Brück
The chemokine receptor CCR2 is involved in macrophage recruitment to the injured peripheral nervous system.
Journal of neuroimmunology 2000;110(1-2):177-85.
2000: T M Black; P Wang; Nobuyo Maeda; Rosalind A Coleman
Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation.
The Journal of nutrition 2000;130(10):2420-6.
2000: Kathryn G Lamping; Daniel W Nuno; Edward Shesely; Nobuyo Maeda; Frank M Faraci
Vasodilator mechanisms in the coronary circulation of endothelial nitric oxide synthase-deficient mice.
American journal of physiology. Heart and circulatory physiology 2000;279(4):H1906-12.
2000: Steven R Lentz; Rochelle A Erger; Sanjana Dayal; Nobuyo Maeda; M Rene Malinow; Donald D Heistad; Frank M Faraci
Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice.
American journal of physiology. Heart and circulatory physiology 2000;279(3):H970-5.
2000: E Bush; Nobuyo Maeda; William Kuziel; Tracey C Dawson; Josiah N Wilcox; Hector Deleon; W. Robert Taylor
CC chemokine receptor 2 is required for macrophage infiltration and vascular hypertrophy in angiotensin II-induced hypertension.
Hypertension 2000;36(3):360-3.
2000: T C Dawson; A B Lentsch; Zixuan Wang; J E Cowhig; A Rot; Nobuyo Maeda; Stephen Peiper
Exaggerated response to endotoxin in mice lacking the Duffy antigen/receptor for chemokines (DARC).
Blood 2000;96(5):1681-4.
2000: Pietro G Andres; Paul L Beck; Emiko Mizoguchi; Atsushi Mizoguchi; Atul K Bhan; T Dawson; William Kuziel; Nobuyo Maeda; RP MacDermott; Daniel K Podolsky; Hans-Christian Reinecker
Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(12):6303-12.
2000: Tiziana Parasassi; W Yu; D Durbin; L Kuriashkina; Enrico Gratton; Nobuyo Maeda; Fulvio Ursini
Two-photon microscopy of aorta fibers shows proteolysis induced by LDL hydroperoxides.
Free radical biology & medicine 2000;28(11):1589-97.
2000: Tracey C Dawson; Melinda A Beck; William Kuziel; F Henderson; Nobuyo Maeda
Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus.
The American journal of pathology 2000;156(6):1951-9.
2000: O Yasuda; S H Zhang; Y Miyamoto; Nobuyo Maeda
Differential expression of the alpha1 type VIII collagen gene by smooth muscle cells from atherosclerotic plaques of apolipoprotein-E-deficient mice.
Journal of vascular research 2000;37(3):158-69.
2000: Peter Heeringa; Harry van Goor; Yoshie Itoh-Lindstrom; Nobuyo Maeda; Ronald J Falk; K J Assmann; C G Kallenberg; John Jennette
Lack of endothelial nitric oxide synthase aggravates murine accelerated anti-glomerular basement membrane glomerulonephritis.
The American journal of pathology 2000;156(3):879-88.
2000: J W Knowles; Robert L Reddick; John Jennette; Edward Shesely; Oliver Smithies; Nobuyo Maeda
Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment.
The Journal of clinical investigation 2000;105(4):451-8.
2000: Nobuyo Maeda; H Hagihara; Y Nakata; S Hiller; J Wilder; Robert L Reddick
Aortic wall damage in mice unable to synthesize ascorbic acid.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):841-6.
1999: Rai Ajit Srivastava; L Toth; N Srivastava; M E Hinsdale; Nobuyo Maeda; A B Cefalu; Maurizio R Averna; Gustav Schonfeld
Regulation of the apolipoprotein B in heterozygous hypobetalipoproteinemic knock-out mice expressing truncated apoB, B81. Low production and enhanced clearance of apoB cause low levels of apoB.
Molecular and cellular biochemistry 1999;202(1-2):37-46.
1999: N Sato; William Kuziel; Peter C Melby; Robert L Reddick; V Kostecki; W Zhao; Nobuyo Maeda; Sunil Ahuja; Seema Ahuja
Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5519-25.
1999: Kailash N Pandey; Paula M Oliver; Nobuyo Maeda; Oliver Smithies
Hypertension associated with decreased testosterone levels in natriuretic peptide receptor-A gene-knockout and gene-duplicated mutant mouse models.
Endocrinology 1999;140(11):5112-9.
1999: Gary B Huffnagle; LK McNeil; Roderick A McDonald; Juneann W Murphy; Galen Toews; Nobuyo Maeda; William Kuziel
Cutting edge: Role of C-C chemokine receptor 5 in organ-specific and innate immunity to Cryptococcus neoformans.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):4642-6.
1999: Masao Mato; Shigeo Ookawara; Toshihiro Mashiko; A Sakamoto; Takashi Mato; Nobuyo Maeda; Tsunenori Kodama
Regional difference of lipid distribution in brain of apolipoprotein E deficient mice.
The Anatomical record 1999;256(2):165-76.
1999: Kristy D Lake-Bruse; Frank M Faraci; Edward Shesely; Nobuyo Maeda; Curt D Sigmund; Donald D Heistad
Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOS-deficient mice.
The American journal of physiology 1999;277(2 Pt 2):H770-6.
1999: Christopher Knouff; Myron E Hinsdale; Hafid Mezdour; mike altenburg; M Watanabe; SH Quarfordt; Patrick M. Sullivan; Nobuyo Maeda
Apo E structure determines VLDL clearance and atherosclerosis risk in mice.
The Journal of clinical investigation 1999;103(11):1579-86.
1999: Chao Qi; Yijun Zhu; J Pan; Nobuteru Usuda; Nobuyo Maeda; Anjana V Yeldandi; M Sambasiva Rao; Takashi Hashimoto; Janardan K Reddy
Absence of spontaneous peroxisome proliferation in enoyl-CoA Hydratase/L-3-hydroxyacyl-CoA dehydrogenase-deficient mouse liver. Further support for the role of fatty acyl CoA oxidase in PPARalpha ligand metabolism.
The Journal of biological chemistry 1999;274(22):15775-80.
1999: Hyung-Suk Kim; Nobuyo Maeda; G T Oh; Lucas Guillermo Fernandez; R Ariel Gomez; Oliver Smithies
Homeostasis in mice with genetically decreased angiotensinogen is primarily by an increased number of renin-producing cells.
The Journal of biological chemistry 1999;274(20):14210-7.
1999: Tracey C Dawson; William Kuziel; T A Osahar; Nobuyo Maeda
Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice.
Atherosclerosis 1999;143(1):205-11.
1999: Chao Qi; Yijun Zhu; J Pan; Anjana V Yeldandi; M Sambasiva Rao; Nobuyo Maeda; V Subbarao; S Pulikuri; Takashi Hashimoto; Janardan K Reddy
Mouse steroid receptor coactivator-1 is not essential for peroxisome proliferator-activated receptor alpha-regulated gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1585-90.
1999: Seigo Hatada; William Kuziel; Oliver Smithies; Nobuyo Maeda
The influence of chromosomal location on the expression of two transgenes in mice.
The Journal of biological chemistry 1999;274(2):948-55.
1998: Michael I Oliverio; Hyung-Suk Kim; M Ito; T Le; Laurent P Audoly; CF Best; S Hiller; Kimberly D Kluckman; Nobuyo Maeda; Oliver Smithies; Thomas M Coffman
Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15496-501.
1998: Robert L Reddick; S H Zhang; Nobuyo Maeda
Aortic atherosclerotic plaque injury in apolipoprotein E deficient mice.
Atherosclerosis 1998;140(2):297-305.
1998: Patrick M. Sullivan; Hafid Mezdour; SH Quarfordt; Nobuyo Maeda
Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2.
The Journal of clinical investigation 1998;102(1):130-5.
1998: D S Howland; Stephen P Trusko; Mary J Savage; Andrew G Reaume; D M Lang; J D Hirsch; Nobuyo Maeda; Robert Siman; Barry D Greenberg; Richard W Scott; Dorothy G Flood
Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol.
The Journal of biological chemistry 1998;273(26):16576-82.
1998: Sylvie Braschi; N Couture; A Gambarotta; B R Gauthier; Cynthia R Coffill; Daniel L Sparks; Nobuyo Maeda; Joshua R Schultz
Hepatic lipase affects both HDL and ApoB-containing lipoprotein levels in the mouse.
Biochimica et biophysica acta 1998;1392(2-3):276-90.
1998: H Rosen; Alon Reshef; Nobuyo Maeda; A Lippoldt; Shoshi Shpizen; L Triger; G Eggertsen; Ingemar Björkhem; eran leitersdorf
Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene.
The Journal of biological chemistry 1998;273(24):14805-12.
1998: Z Zhu; S H Zhang; C Wagner; A Kurtz; Nobuyo Maeda; Thomas M Coffman; William J Arendshorst
Angiotensin AT1B receptor mediates calcium signaling in vascular smooth muscle cells of AT1A receptor-deficient mice.
Hypertension 1998;31(5):1171-7.
1998: Udo Seedorf; M Raabe; Peter Ellinghaus; Frank Kannenberg; Manfred Fobker; Thomas Engel; Simone Denis; FS Wouters; Karel W A Wirtz; Ronald J A Wanders; Nobuyo Maeda; Gerd Assmann
Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function.
Genes & development 1998;12(8):1189-201.
1998: Jada Lewis; B Yang; R Kim; Halina Sierakowska; Ryszard Kole; Oliver Smithies; Nobuyo Maeda
A common human beta globin splicing mutation modeled in mice.
Blood 1998;91(6):2152-6.
1998: N Fujita; A Kemper; Jeffrey L Dupree; H Nakayasu; U Bartsch; M Schachner; Nobuyo Maeda; Koichi Suzuki; Brian Popko
The cytoplasmic domain of the large myelin-associated glycoprotein isoform is needed for proper CNS but not peripheral nervous system myelination.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(6):1970-8.
1998: Paula M Oliver; S W John; K E Purdy; R Kim; Nobuyo Maeda; Michael F Goy; Oliver Smithies
Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2547-51.
1998: Radu Daniel Rudic; Edward Shesely; Nobuyo Maeda; Oliver Smithies; Steven S Segal; William C Sessa
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.
The Journal of clinical investigation 1998;101(4):731-6.
1998: Frank M Faraci; Curt D Sigmund; Edward Shesely; Nobuyo Maeda; Donald D Heistad
Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase.
The American journal of physiology 1998;274(2 Pt 2):H564-70.
1998: Allen D Roses; John Gilbert; Pu-Ting Xu; Patrick M. Sullivan; Brian Popko; D S Burkhart; T Christian-Rothrock; Ann M Saunders; Nobuyo Maeda; Donald E Schmechel
Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice.
Neurobiology of aging 1998;19(1 Suppl):S53-8.
1998: Michael I Oliverio; K Madsen; CF Best; M Ito; Nobuyo Maeda; Oliver Smithies; Thomas M Coffman
Renal growth and development in mice lacking AT1A receptors for angiotensin II.
The American journal of physiology 1998;274(1 Pt 2):F43-50.
1997: Paula M Oliver; JE Fox; R Kim; Howard A Rockman; Hyung-Suk Kim; Robert L Reddick; Kailash N Pandey; Sharon L Milgram; Oliver Smithies; Nobuyo Maeda
Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14730-5.
1997: L Lanoue; Deborah B Dehart; Myron E Hinsdale; Nobuyo Maeda; Stephen G Tint; Kathleen K Sulik
Limb, genital, CNS, and facial malformations result from gene/environment-induced cholesterol deficiency: further evidence for a link to sonic hedgehog.
American journal of medical genetics 1997;73(1):24-31.
1997: Hui-Feng Lin; Nobuyo Maeda; Oliver Smithies; David L Straight; Darrel W Stafford
A coagulation factor IX-deficient mouse model for human hemophilia B.
Blood 1997;90(10):3962-6.
1997: William Kuziel; S J Morgan; Tracey C Dawson; S Griffin; Oliver Smithies; K Ley; Nobuyo Maeda
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):12053-8.
1997: Y Huang; Y Zhu; Claus Langer; M Raabe; S Wu; B Wiesenhütter; Udo Seedorf; Nobuyo Maeda; Gerd Assmann; Arnold von Eckardstein
Effects of genotype and diet on cholesterol efflux into plasma and lipoproteins of normal, apolipoprotein A-I-, and apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(10):2010-9.
1997: Patrick M. Sullivan; Hafid Mezdour; Y Aratani; Christopher Knouff; J Najib; Robert L Reddick; SH Quarfordt; Nobuyo Maeda
Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis.
The Journal of biological chemistry 1997;272(29):17972-80.
1997: John Krege; Jeffrey S Moyer; L L Langenbach; Lin Peng; S H Zhang; Nobuyo Maeda; Robert L Reddick; Oliver Smithies
Angiotensin-converting enzyme gene and atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(7):1245-50.
1997: H Tsuda; C E Maynard-Currie; L H Reid; T Yoshida; K Edamura; Nobuyo Maeda; Oliver Smithies; Aya Jakobovits
Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines.
Genomics 1997;42(3):413-21.
1997: S H Zhang; Robert L Reddick; E Avdievich; L K Surles; R G Jones; J B Reynolds; SH Quarfordt; Nobuyo Maeda
Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice.
The Journal of clinical investigation 1997;99(12):2858-66.
1997: Hafid Mezdour; R Jones; C Dengremont; Graciela Castro; Nobuyo Maeda
Hepatic lipase deficiency increases plasma cholesterol but reduces susceptibility to atherosclerosis in apolipoprotein E-deficient mice.
The Journal of biological chemistry 1997;272(21):13570-5.
1996: C Y Fan; J Pan; R Chu; D Lee; K D Kluckman; Nobuteru Usuda; Inderjit Singh; Anjana V Yeldandi; M Sambasiva Rao; Nobuyo Maeda; Janardan K Reddy
Targeted disruption of the peroxisomal fatty acyl-CoA oxidase gene: generation of a mouse model of pseudoneonatal adrenoleukodystrophy.
Annals of the New York Academy of Sciences 1996;804():530-41.
1996: Edward Shesely; Nobuyo Maeda; Hyung-Suk Kim; K M Desai; John Krege; Victor E Laubach; P A Sherman; William C Sessa; Oliver Smithies
Elevated blood pressures in mice lacking endothelial nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13176-81.
1996: L R Toth; T J Smith; C Jones; H V de Silva; Oliver Smithies; Nobuyo Maeda
Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting.
Gene 1996;178(1-2):161-8.
1996: C Y Fan; J Pan; R Chu; D Lee; K D Kluckman; Nobuteru Usuda; I Singh; Anjana V Yeldandi; M Sambasiva Rao; Nobuyo Maeda; Janardan K Reddy
Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene.
The Journal of biological chemistry 1996;271(40):24698-710.
1996: S K Bronson; E G Plaehn; K D Kluckman; J R Hagaman; Nobuyo Maeda; Oliver Smithies
Single-copy transgenic mice with chosen-site integration.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9067-72.
1996: S Chang; Nobuyo Maeda; Jayme Borensztajn
The role of lipoprotein lipase and apoprotein E in the recognition of chylomicrons and chylomicron remnants by cultured isolated mouse hepatocytes.
The Biochemical journal 1996;318 ( Pt 1)():29-34.
1996: Jörg Tatzelt; Nobuyo Maeda; Milos Pekny; S L Yang; C Betsholtz; Camilla Eliasson; J Cayetano; A P Camerino; Stephen J DeArmond; Stanley B Prusiner
Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein.
Neurology 1996;47(2):449-53.
1996: N Fujita; Kunihiko Suzuki; marie T vanier; Brian Popko; Nobuyo Maeda; A Klein; M Henseler; Konrad Sandhoff; H Nakayasu; Kinuko Suzuki
Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids.
Human molecular genetics 1996;5(6):711-25.
1996: Pu-Ting Xu; Donald E Schmechel; T Rothrock-Christian; D S Burkhart; H L Qiu; Brian Popko; Patrick M. Sullivan; Nobuyo Maeda; Ann M Saunders; Allen D Roses; John Gilbert
Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.
Neurobiology of disease 1996;3(3):229-45.
1995: B Yang; Suzanne L Kirby; Jada Lewis; P J Detloff; Nobuyo Maeda; Oliver Smithies
A mouse model for beta 0-thalassemia.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11608-12.
1995: V S Kashyap; Silvia Santamarina-Fojo; D R Brown; C L Parrott; D Applebaum-Bowden; S Meyn; GD Talley; Beverly Paigen; Nobuyo Maeda; H Bryan Brewer
Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors.
The Journal of clinical investigation 1995;96(3):1612-20.
1995: L M Erickson; Nobuyo Maeda
A new family of retroviral long terminal repeat elements in the human genome identified by their homologies to an element 5' to the spider monkey haptoglobin gene.
Genomics 1995;27(3):531-4.
1995: Oliver Smithies; Nobuyo Maeda
Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5266-72.
1995: SH Quarfordt; B Oswald; B Landis; H S Xu; S H Zhang; Nobuyo Maeda
In vivo cholesterol kinetics in apolipoprotein E-deficient and control mice.
Journal of lipid research 1995;36(6):1227-35.
1995: Trey Coleman; Richard L Seip; J M Gimble; D Lee; Nobuyo Maeda; Clay F Semenkovich
COOH-terminal disruption of lipoprotein lipase in mice is lethal in homozygotes, but heterozygotes have elevated triglycerides and impaired enzyme activity.
The Journal of biological chemistry 1995;270(21):12518-25.
1995: M Ito; Michael I Oliverio; PJ Mannon; CF Best; Nobuyo Maeda; Oliver Smithies; Thomas M Coffman
Regulation of blood pressure by the type 1A angiotensin II receptor gene.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3521-5.
1995: Hyung-Suk Kim; John Krege; K D Kluckman; J R Hagaman; Jeffrey B Hodgin; CF Best; John Jennette; Thomas M Coffman; Nobuyo Maeda; Oliver Smithies
Genetic control of blood pressure and the angiotensinogen locus.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2735-9.
1995: M Watanabe; J Osada; Y Aratani; K Kluckman; Robert L Reddick; M R Malinow; Nobuyo Maeda
Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1585-9.
1995: G E Homanics; H V de Silva; J Osada; S H Zhang; H Wong; Jayme Borensztajn; Nobuyo Maeda
Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene.
The Journal of biological chemistry 1995;270(7):2974-80.
1995: Kenneth R Feingold; Peter M Elias; M Mao-Qiang; Manige Fartasch; S H Zhang; Nobuyo Maeda
Apolipoprotein E deficiency leads to cutaneous foam cell formation in mice.
The Journal of investigative dermatology 1995;104(2):246-50.
1995: John S Parks; H Li; Abraham K Gebre; T L Smith; Nobuyo Maeda
Effect of apolipoprotein A-I deficiency on lecithin:cholesterol acyltransferase activation in mouse plasma.
Journal of lipid research 1995;36(2):349-55.
1995: JF Goodrum; Thomas W Bouldin; S H Zhang; Nobuyo Maeda; Brian Popko
Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice.
Journal of neurochemistry 1995;64(1):408-16.
1995: G E Homanics; Nobuyo Maeda; M G Traber; H J Kayden; Deborah B Dehart; Kathleen K Sulik
Exencephaly and hydrocephaly in mice with targeted modification of the apolipoprotein B (Apob) gene.
Teratology 1995;51(1):1-10.
1994: S Chang; S H Zhang; Nobuyo Maeda; Jayme Borensztajn
Hepatic clearance of chylomicron remnants in mice lacking apoprotein E.
Biochimica et biophysica acta 1994;1215(1-2):205-8.
1994: P J Detloff; Jada Lewis; Simon W M John; W R Shehee; Robert Langenbach; Nobuyo Maeda; Oliver Smithies
Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.
Molecular and cellular biology 1994;14(10):6936-43.
1994: Nobuyo Maeda; H Li; D Lee; P Oliver; S H Quarfordt; J Osada
Targeted disruption of the apolipoprotein C-III gene in mice results in hypotriglyceridemia and protection from postprandial hypertriglyceridemia.
The Journal of biological chemistry 1994;269(38):23610-6.
1994: S H Zhang; Robert L Reddick; B Burkey; Nobuyo Maeda
Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption.
The Journal of clinical investigation 1994;94(3):937-45.
1994: C Pászty; Nobuyo Maeda; JB Verstuyft; Edward M Rubin
Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice.
The Journal of clinical investigation 1994;94(2):899-903.
1994: L M Erickson; Nobuyo Maeda
Parallel evolutionary events in the haptoglobin gene clusters of rhesus monkey and human.
Genomics 1994;22(3):579-89.
1994: S Ishibashi; Joachim Herz; Nobuyo Maeda; Joseph L Goldstein; Michael S Brown
The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4431-5.
1994: Y Huang; Arnold von Eckardstein; S Wu; Nobuyo Maeda; Gerd Assmann
A plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1834-8.
1994: Robert L Reddick; S H Zhang; Nobuyo Maeda
Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(1):141-7.
1993: H Li; Robert L Reddick; Nobuyo Maeda
Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(12):1814-21.
1993: C Purtell; Nobuyo Maeda; D L Ebert; M Kaiser; S Lund-Katz; Stephen L. Sturley; V Kodoyianni; K Grunwald; D N Nevin; R J Aiello
Nucleotide sequence encoding the carboxyl-terminal half of apolipoprotein B from spontaneously hypercholesterolemic pigs.
Journal of lipid research 1993;34(8):1323-35.
1993: D J Grant; Nobuyo Maeda
A base substitution in the promoter associated with the human haptoglobin 2-1 modified phenotype decreases transcriptional activity and responsiveness to interleukin-6 in human hepatoma cells.
American journal of human genetics 1993;52(5):974-80.
1993: G E Homanics; T J Smith; S H Zhang; D Lee; S G Young; Nobuyo Maeda
Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2389-93.
1993: Brian Popko; JF Goodrum; Thomas W Bouldin; S H Zhang; Nobuyo Maeda
Nerve regeneration occurs in the absence of apolipoprotein E in mice.
Journal of neurochemistry 1993;60(3):1155-8.
1993: Hyung-Suk Kim; K M Lyons; Eiichi Saitoh; Edwin Azen; Oliver Smithies; Nobuyo Maeda
The structure and evolution of the human salivary proline-rich protein gene family.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(1):3-14.
1992: L M Erickson; Hyung-Suk Kim; Nobuyo Maeda
Junctions between genes in the haptoglobin gene cluster of primates.
Genomics 1992;14(4):948-58.
1992: S H Zhang; Robert L Reddick; J A Piedrahita; Nobuyo Maeda
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E.
Science (New York, N.Y.) 1992;258(5081):468-71.
1992: J A Piedrahita; L Gillespie; Nobuyo Maeda
Production of chimeric hamsters by aggregation of eight-cell embryos.
Biology of reproduction 1992;47(3):347-54.
1992: R Williamson; D Lee; J Hagaman; Nobuyo Maeda
Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7134-8.
1992: J A Piedrahita; S H Zhang; J R Hagaman; Paula M Oliver; Nobuyo Maeda
Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4471-5.
1991: F Schwartz; Nobuyo Maeda; Oliver Smithies; Robert Hickey; Winfried Edelmann; Arthur I Skoultchi; R Kucherlapati
A dominant positive and negative selectable gene for use in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10416-20.
1991: Nobuyo Maeda
DNA polymorphisms in the controlling region of the human haptoglobin genes: a molecular explanation for the haptoglobin 2-1 modified phenotype.
American journal of human genetics 1991;49(1):158-66.
1990: Nobuyo Maeda; Hyung-Suk Kim
Three independent insertions of retrovirus-like sequences in the haptoglobin gene cluster of primates.
Genomics 1990;8(4):671-83.
1990: T J Smith; D Hautamaa; Nobuyo Maeda
Sequence of the putative low-density lipoprotein receptor-binding regions of apolipoprotein B in mouse and hamster.
Gene 1990;87(2):309-10.
1990: Hyung-Suk Kim; Oliver Smithies; Nobuyo Maeda
A physical map of the human salivary proline-rich protein gene cluster covers over 700 kbp of DNA.
Genomics 1990;6(2):260-7.
1989: Beverly H Koller; L J Hagemann; T Doetschman; J R Hagaman; S Huang; P J Williams; N L First; Nobuyo Maeda; Oliver Smithies
Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(22):8927-31.
1988: J Krisinger; H Darwish; Nobuyo Maeda; Hector F Deluca
Structure and nucleotide sequence of the rat intestinal vitamin D-dependent calcium binding protein gene.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):8988-92.
1988: J K Burmester; R J Wiese; Nobuyo Maeda; Hector F Deluca
Structure and regulation of the rat 1,25-dihydroxyvitamin D3 receptor.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9499-502.
1988: D L Ebert; Nobuyo Maeda; Scott W Lowe; J Hasler-Rapacz; J Rapacz; Alan D Attie
Primary structure comparison of the proposed low density lipoprotein (LDL) receptor binding domain of human and pig apolipoprotein B: implications for LDL-receptor interactions.
Journal of lipid research 1988;29(11):1501-9.
1988: T Doetschman; Nobuyo Maeda; Oliver Smithies
Targeted mutation of the Hprt gene in mouse embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8583-7.
1988: Nobuyo Maeda; D L Ebert; T M Doers; M Newman; J Hasler-Rapacz; Alan D Attie; J Rapacz; Oliver Smithies
Molecular genetics of the apolipoprotein B gene in pigs in relation to atherosclerosis.
Gene 1988;70(2):213-29.
1988: S M McEvoy; Nobuyo Maeda
Complex events in the evolution of the haptoglobin gene cluster in primates.
The Journal of biological chemistry 1988;263(30):15740-7.
1988: T Doetschman; P Williams; Nobuyo Maeda
Establishment of hamster blastocyst-derived embryonic stem (ES) cells.
Developmental biology 1988;127(1):224-7.
1988: Eiichi Saitoh; S Isemura; K Sanada; Hyung-Suk Kim; Oliver Smithies; Nobuyo Maeda
Cystatin superfamily. Evidence that family II cystatin genes are evolutionarily related to family III cystatin genes.
Biological chemistry Hoppe-Seyler 1988;369 Suppl():191-7.
1988: J K Burmester; Nobuyo Maeda; Hector F Deluca
Isolation and expression of rat 1,25-dihydroxyvitamin D3 receptor cDNA.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1005-9.
1988: Nobuyo Maeda; C I Wu; J Bliska; J Reneke
Molecular evolution of intergenic DNA in higher primates: pattern of DNA changes, molecular clock, and evolution of repetitive sequences.
Molecular biology and evolution 1988;5(1):1-20.
1988: Edwin Azen; Nobuyo Maeda
Molecular genetics of human salivary proteins and their polymorphisms.
Advances in human genetics 1988;17():141-99.
1987: T Doetschman; R G Gregg; Nobuyo Maeda; M L Hooper; David W Melton; S Thompson; Oliver Smithies
Targetted correction of a mutant HPRT gene in mouse embryonic stem cells.
Nature 1987;330(6148):576-8.
1987: Edwin Azen; Hyung-Suk Kim; P Goodman; S Flynn; Nobuyo Maeda
Alleles at the PRH1 locus coding for the human salivary-acidic proline-rich proteins Pa, Db, and PIF.
American journal of human genetics 1987;41(6):1035-47.
1987: K Y Song; F Schwartz; Nobuyo Maeda; Oliver Smithies; R Kucherlapati
Accurate modification of a chromosomal plasmid by homologous recombination in human cells.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(19):6820-4.
1987: E Saitoh; Hyung-Suk Kim; Oliver Smithies; Nobuyo Maeda
Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family.
Gene 1987;61(3):329-38.
1986: Nobuyo Maeda; S M McEvoy; H F Harris; T H Huisman; Oliver Smithies
Polymorphisms in the human haptoglobin gene cluster: chromosomes with multiple haptoglobin-related (Hpr) genes.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7395-9.
1986: H S Kim; Nobuyo Maeda
Structures of two HaeIII-type genes in the human salivary proline-rich protein multigene family.
The Journal of biological chemistry 1986;261(15):6712-8.
1986: Nobuyo Maeda; Oliver Smithies
The evolution of multigene families: human haptoglobin genes.
Annual review of genetics 1986;20():81-108.
1985: Nobuyo Maeda; Hyung-Suk Kim; E A Azen; Oliver Smithies
Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system.
The Journal of biological chemistry 1985;260(20):11123-30.
1985: Nobuyo Maeda
Nucleotide sequence of the haptoglobin and haptoglobin-related gene pair. The haptoglobin-related gene contains a retrovirus-like element.
The Journal of biological chemistry 1985;260(11):6698-709.
1984: Nobuyo Maeda; D X Zhu; W M Fitch
Amino acid sequences of lower vertebrate parvalbumins and their evolution: parvalbumins of boa, turtle, and salamander.
Molecular biology and evolution 1984;1(6):473-88.
1984: Edwin Azen; K M Lyons; T McGonigal; N L Barrett; L S Clements; Nobuyo Maeda; E F Vanin; D M Carlson; Oliver Smithies
Clones from the human gene complex coding for salivary proline-rich proteins.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(17):5561-5.
1984: Nobuyo Maeda; Funmei Yang; D R Barnett; B H Bowman; Oliver Smithies
Duplication within the haptoglobin Hp2 gene.
Nature 1984;309(5964):131-5.
1983: Nobuyo Maeda; J B Bliska; Oliver Smithies
Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(16):5012-6.