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Simonetta Bartolucci

Research Profile

Living Beings

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Chemicals & Drugs

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Cloning, Molecular

Physiology

Gene Expression Regulation, Archaeal

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Publications

TOP 3
Salvatore Fusco; Qunxin She; Simonetta Bartolucci; Patrizia Contursi
Tlys, a Newly Identified Sulfolobus Spindle-Shaped Virus 1 Transcript Expressed in the Lysogenic State, Encodes a DNA-Binding Protein Interacting at the Promoters of the Early Genes.
Simonetta Bartolucci; Patrizia Contursi; Gabriella Fiorentino; Danila Limauro; Emilia Pedone
Responding to toxic compounds: a genomic and functional overview of Archaea.
Danila Limauro; Katia D'Ambrosio; Emma Langella; Giuseppina De simone; Ilaria Galdi; Carlo Pedone; Emilia Pedone; Simonetta Bartolucci
Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus.

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All Publications

2013: Salvatore Fusco; Qunxin She; Simonetta Bartolucci; Patrizia Contursi
Tlys, a Newly Identified Sulfolobus Spindle-Shaped Virus 1 Transcript Expressed in the Lysogenic State, Encodes a DNA-Binding Protein Interacting at the Promoters of the Early Genes.
Journal of virology 2013;87(10):5926-36.
2013: Simonetta Bartolucci; Patrizia Contursi; Gabriella Fiorentino; Danila Limauro; Emilia Pedone
Responding to toxic compounds: a genomic and functional overview of Archaea.
Frontiers in bioscience : a journal and virtual library 2013;18():165-89.
2010: Danila Limauro; Katia D'Ambrosio; Emma Langella; Giuseppina De simone; Ilaria Galdi; Carlo Pedone; Emilia Pedone; Simonetta Bartolucci
Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus.
Biochimie 2010;92(10):1435-44.
2009: Gabriella Fiorentino; Raffaele Ronca; Simonetta Bartolucci
A novel E. coli biosensor for detecting aromatic aldehydes based on a responsive inducible archaeal promoter fused to the green fluorescent protein.
Applied microbiology and biotechnology 2009;82(1):67-77.
2008: Santina Prato; Rosa Maria Vitale; Patrizia Contursi; Georg Lipps; Michele Saviano; Mosé Rossi; Simonetta Bartolucci
Molecular modeling and functional characterization of the monomeric primase-polymerase domain from the Sulfolobus solfataricus plasmid pIT3.
The FEBS journal 2008;275(17):4389-402.
2008: Danila Limauro; Emilia Pedone; Ilaria Galdi; Simonetta Bartolucci
Peroxiredoxins as cellular guardians in Sulfolobus solfataricus: characterization of Bcp1, Bcp3 and Bcp4.
The FEBS journal 2008;275(9):2067-77.
2008: Emilia Pedone; Danila Limauro; Simonetta Bartolucci
The machinery for oxidative protein folding in thermophiles.
Antioxidants & redox signaling 2008;10(1):157-69.
2007: Gabriella Fiorentino; Raffaele Ronca; Raffaele Cannio; Mosè Rossi; Simonetta Bartolucci
MarR-like transcriptional regulator involved in detoxification of aromatic compounds in Sulfolobus solfataricus.
Journal of bacteriology 2007;189(20):7351-60.
2007: Patrizia Contursi; Raffaele Cannio; Santina Prato; Qunxin She; Mosè Rossi; Simonetta Bartolucci
Transcriptional analysis of the genetic element pSSVx: differential and temporal regulation of gene expression reveals correlation between transcription and replication.
Journal of bacteriology 2007;189(17):6339-50.
2006: Emilia Pedone; Danila Limauro; Romina D'Alterio; Mosè Rossi; Simonetta Bartolucci
Characterization of a multifunctional protein disulfide oxidoreductase from Sulfolobus solfataricus.
The FEBS journal 2006;273(23):5407-20.
2006: Patrizia Contursi; Susanne Jensen; Tiziana Aucelli; Mosé Rossi; Simonetta Bartolucci; Qunxin She
Characterization of the Sulfolobus host-SSV2 virus interaction.
Extremophiles : life under extreme conditions 2006;10(6):615-27.
2006: Katia D'Ambrosio; Emilia Pedone; Emma Langella; Giuseppina De simone; Mosè Rossi; Carlo Pedone; Simonetta Bartolucci
A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: structure, function and electrostatics.
Journal of molecular biology 2006;362(4):743-52.
2006: Santina Prato; Raffaele Cannio; Hans-Peter Klenk; Patrizia Contursi; Mosè Rossi; Simonetta Bartolucci
pIT3, a cryptic plasmid isolated from the hyperthermophilic crenarchaeon Sulfolobus solfataricus IT3.
Plasmid 2006;56(1):35-45.
2006: Emilia Pedone; Katia D'Ambrosio; Giuseppina De simone; Mosè Rossi; Carlo Pedone; Simonetta Bartolucci
Insights on a new PDI-like family: structural and functional analysis of a protein disulfide oxidoreductase from the bacterium Aquifex aeolicus.
Journal of molecular biology 2006;356(1):155-64.
2006: Danila Limauro; Emilia Pedone; Luciano Pirone; Simonetta Bartolucci
Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress.
The FEBS journal 2006;273(4):721-31.
2005: Emilia Pedone; Michele Saviano; Simonetta Bartolucci; Mosè Rossi; Alessio Ausili; andrea scirè; Enrico Bertoli; Fabio Tanfani
Temperature-, SDS-, and pH-induced conformational changes in protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: a dynamic simulation and fourier transform infrared spectroscopic study.
Journal of proteome research 2005;4(6):1972-80.
2005: Katia D'Ambrosio; Giuseppina De simone; Emilia Pedone; Mosè Rossi; Simonetta Bartolucci; Carlo Pedone
Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aeropyrum pernix K1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 3):335-6.
2004: Katia D'Ambrosio; Giuseppina De simone; Emilia Pedone; Mosè Rossi; Simonetta Bartolucci; Carlo Pedone
Crystallization and preliminary X-ray diffraction studies of a protein disulfide oxidoreductase from Aquifex aeolicus.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 11):2076-7.
2004: Patrizia Contursi; Francesca M Pisani; Andrei Grigoriev; Raffaele Cannio; Simonetta Bartolucci; Mosè Rossi
Identification and autonomous replication capability of a chromosomal replication origin from the archaeon Sulfolobus solfataricus.
Extremophiles : life under extreme conditions 2004;8(5):385-91.
2004: Emilia Pedone; Simonetta Bartolucci; Gabriella Fiorentino
Sensing and adapting to environmental stress: the archaeal tactic.
Frontiers in bioscience : a journal and virtual library 2004;9():2909-26.
2004: Emilia Pedone; Bin Ren; Rudolf Ladenstein; Mosè Rossi; Simonetta Bartolucci
Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: a member of a novel protein family related to protein disulfide-isomerase.
European journal of biochemistry / FEBS 2004;271(16):3437-48.
2004: Marilisa Leone; Paola Di Lello; Oliver Ohlenschläger; Emilia Pedone; Simonetta Bartolucci; Mosè Rossi; Benedetto Di Blasio; Carlo Pedone; Michele Saviano; Carla Isernia; Roberto Fattorusso
Solution structure and backbone dynamics of the K18G/R82E Alicyclobacillus acidocaldarius thioredoxin mutant: a molecular analysis of its reduced thermal stability.
Biochemistry 2004;43(20):6043-58.
2004: Silvana Sacchetti; Simonetta Bartolucci; Mosè Rossi; Raffaele Cannio
Identification of a GDP-mannose pyrophosphorylase gene from Sulfolobus solfataricus.
Gene 2004;332():149-57.
2003: Filomena Anna Digilio; Rosa Morra; Emilia Pedone; Simonetta Bartolucci; Mosè Rossi
High-level expression of Aliciclobacillus acidocaldarius thioredoxin in Pichia pastoris and Bacillus subtilis.
Protein expression and purification 2003;30(2):179-84.
2003: Emilia Pedone; Simonetta Bartolucci; Mosè Rossi; Francesco-Maria Pierfederici; andrea scirè; Tiziana Cacciamani; Fabio Tanfani
Structural and thermal stability analysis of Escherichia coli and Alicyclobacillus acidocaldarius thioredoxin revealed a molten globule-like state in thermal denaturation pathway of the proteins: an infrared spectroscopic study.
The Biochemical journal 2003;373(Pt 3):875-83.
2003: Simonetta Bartolucci; Giuseppina De simone; stefania galdiero; Roberto Improta; Valeria Menchise; Carlo Pedone; Emilia Pedone; Michele Saviano
An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius.
Journal of bacteriology 2003;185(14):4285-9.
2003: Simonetta Bartolucci; Mosè Rossi; Raffaele Cannio
Characterization and functional complementation of a nonlethal deletion in the chromosome of a beta-glycosidase mutant of Sulfolobus solfataricus.
Journal of bacteriology 2003;185(13):3948-57.
2003: Gabriella Fiorentino; Raffaele Cannio; Mosè Rossi; Simonetta Bartolucci
Transcriptional regulation of the gene encoding an alcohol dehydrogenase in the archaeon Sulfolobus solfataricus involves multiple factors and control elements.
Journal of bacteriology 2003;185(13):3926-34.
2003: Mosè Rossi; Maria Ciaramella; Raffaele Cannio; Francesca M Pisani; Marco Moracci; Simonetta Bartolucci
Extremophiles 2002.
Journal of bacteriology 2003;185(13):3683-9.
2003: Patrizia Contursi; Raffaele Cannio; Santina Prato; Gabriella Fiorentino; Mosè Rossi; Simonetta Bartolucci
Development of a genetic system for hyperthermophilic Archaea: expression of a moderate thermophilic bacterial alcohol dehydrogenase gene in Sulfolobus solfataricus.
FEMS microbiology letters 2003;218(1):115-20.
2001: Danila Limauro; Raffaele Cannio; Gabriella Fiorentino; Mosè Rossi; Simonetta Bartolucci
Identification and molecular characterization of an endoglucanase gene, celS, from the extremely thermophilic archaeon Sulfolobus solfataricus.
Extremophiles : life under extreme conditions 2001;5(4):213-9.
2001: Raffaele Cannio; Patrizia Contursi; Mosè Rossi; Simonetta Bartolucci
Thermoadaptation of a mesophilic hygromycin B phosphotransferase by directed evolution in hyperthermophilic Archaea: selection of a stable genetic marker for DNA transfer into Sulfolobus solfataricus.
Extremophiles : life under extreme conditions 2001;5(3):153-9.
2001: Emilia Pedone; Michele Saviano; Mosè Rossi; Simonetta Bartolucci
A single point mutation (Glu85Arg) increases the stability of the thioredoxin from Escherichia coli.
Protein engineering 2001;14(4):255-60.
2001: Simonetta Bartolucci; D De Pascale; Mosè Rossi
Protein disulfide oxidoreductase from Pyrococcus furiosus: biochemical properties.
Methods in enzymology 2001;334():62-73.
2000: Raffaele Cannio; Gabriella Fiorentino; Alessandra Morana; Mosè Rossi; Simonetta Bartolucci
Oxygen: friend or foe? Archaeal superoxide dismutases in the protection of intra- and extracellular oxidative stress.
Frontiers in bioscience : a journal and virtual library 2000;5():D768-79.
2000: Giuseppe Nicastro; Cesira de Chiara; Emilia Pedone; M Tatò; Mosè Rossi; Simonetta Bartolucci
NMR solution structure of a novel thioredoxin from Bacillus acidocaldarius possible determinants of protein stability.
European journal of biochemistry / FEBS 2000;267(2):403-13.
2000: Raffaele Cannio; Anna D'Angelo; M Rossi; Simonetta Bartolucci
A superoxide dismutase from the archaeon Sulfolobus solfataricus is an extracellular enzyme and prevents the deactivation by superoxide of cell-bound proteins.
European journal of biochemistry / FEBS 2000;267(1):235-43.
1999: A Kohen; Raffaele Cannio; Simonetta Bartolucci; Judith P Klinman
Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase.
Nature 1999;399(6735):496-9.
1999: Emilia Pedone; Raffaele Cannio; Michele Saviano; Mosè Rossi; Simonetta Bartolucci
Prediction and experimental testing of Bacillus acidocaldarius thioredoxin stability.
The Biochemical journal 1999;339 ( Pt 2)():309-17.
1999: A Giordano; Raffaele Cannio; Francesco La Cara; Simonetta Bartolucci; Mosè Rossi; C A Raia
Asn249Tyr substitution at the coenzyme binding domain activates Sulfolobus solfataricus alcohol dehydrogenase and increases its thermal stability.
Biochemistry 1999;38(10):3043-54.
1999: Raffaele Cannio; Gabriella Fiorentino; Mosè Rossi; Simonetta Bartolucci
The alcohol dehydrogenase gene: distribution among Sulfolobales and regulation in Sulfolobus solfataricus.
FEMS microbiology letters 1999;170(1):31-9.
1998: Gabriella Fiorentino; Raffaele Cannio; Mosè Rossi; Simonetta Bartolucci
Decreasing the stability and changing the substrate specificity of the Bacillus stearothermophilus alcohol dehydrogenase by single amino acid replacements.
Protein engineering 1998;11(10):925-30.
1998: Emilia Pedone; Simonetta Bartolucci; Mosè Rossi; Michele Saviano
Computational analysis of the thermal stability in thioredoxins: a molecular dynamics approach.
Journal of biomolecular structure & dynamics 1998;16(2):437-46.
1998: BIN REN; Gudrun Tibbelin; D De Pascale; Mosè Rossi; Simonetta Bartolucci; Rudolf Ladenstein
A protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus contains two thioredoxin fold units.
Nature structural biology 1998;5(7):602-11.
1998: Raffaele Cannio; Patrizia Contursi; Mosè Rossi; Simonetta Bartolucci
An autonomously replicating transforming vector for Sulfolobus solfataricus.
Journal of bacteriology 1998;180(12):3237-40.
1997: Simonetta Bartolucci; Annamaria Guagliardi; Emilia Pedone; D De Pascale; Raffaele Cannio; L Camardella; Mosè Rossi; Giuseppe Nicastro; Cesira de Chiara; P Facci; Giancarlo Mascetti; C Nicolini
Thioredoxin from Bacillus acidocaldarius: characterization, high-level expression in Escherichia coli and molecular modelling.
The Biochemical journal 1997;328 ( Pt 1)():277-85.
1996: A Guagliardi; M Martino; I Iaccarino; M De Rosa; M Rossi; Simonetta Bartolucci
Purification and characterization of the alcohol dehydrogenase from a novel strain of Bacillus stearothermophilus growing at 70 degrees C.
The international journal of biochemistry & cell biology 1996;28(2):239-46.
1996: Raffaele Cannio; Gabriella Fiorentino; P Carpinelli; M Rossi; Simonetta Bartolucci
Cloning and overexpression in Escherichia coli of the genes encoding NAD-dependent alcohol dehydrogenase from two Sulfolobus species.
Journal of bacteriology 1996;178(1):301-5.
1995: A Guagliardi; D De Pascale; Raffaele Cannio; V Nobile; Simonetta Bartolucci; M Rossi
The purification, cloning, and high level expression of a glutaredoxin-like protein from the hyperthermophilic archaeon Pyrococcus furiosus.
The Journal of biological chemistry 1995;270(11):5748-55.
1995: P Carpinelli; Simonetta Bartolucci; F Ruffo
Synthesis and biological activity of five-coordinate platinum(II) complexes including organotin fragments.
Anti-cancer drug design 1995;10(1):43-9.
1994: A Guagliardi; L Cerchia; Simonetta Bartolucci; M Rossi
The chaperonin from the archaeon Sulfolobus solfataricus promotes correct refolding and prevents thermal denaturation in vitro.
Protein science : a publication of the Protein Society 1994;3(9):1436-43.
1994: Raffaele Cannio; M Rossi; Simonetta Bartolucci
A few amino acid substitutions are responsible for the higher thermostability of a novel NAD(+)-dependent bacillar alcohol dehydrogenase.
European journal of biochemistry / FEBS 1994;222(2):345-52.
1994: Raffaele Cannio; D De Pascale; M Rossi; Simonetta Bartolucci
Gene expression of a thermostable beta-galactosidase in mammalian cells and its application in assays of eukaryotic promoter activity.
Biotechnology and applied biochemistry 1994;19 ( Pt 2)():233-44.
1993: P Carpinelli; Francescopaolo Granata; Gabriella Augusti-Tocco; M Rossi; Simonetta Bartolucci
Antiproliferative effects and DNA hypomethylation by 5-aza-2'-deoxycytidine in human neuroblastoma cell lines.
Anti-cancer drugs 1993;4(6):629-35.
1992: A Guagliardi; L Cerchia; M De Rosa; M Rossi; Simonetta Bartolucci
Isolation of a thermostable enzyme catalyzing disulfide bond formation from the archaebacterium Sulfolobus solfataricus.
FEBS letters 1992;303(1):27-30.
1989: Simonetta Bartolucci; M Estenoz; V de Franciscis; P Carpinelli; G L Colucci; Gabriella Augusti-Tocco; M Rossi
Effect of cytidine analogs on cell growth and differentiation on a human neuroblastoma line.
Cell biophysics 1989;15(1-2):67-77.
1989: A Guagliardi; Giuseppe Manco; M Rossi; Simonetta Bartolucci
Stability and activity of a thermostable malic enzyme in denaturants and water-miscible organic solvents.
European journal of biochemistry / FEBS 1989;183(1):25-30.
1989: Simonetta Bartolucci; M Estenoz; A Longo; B Santoro; Richard L Momparler; M Rossi; Gabriella Augusti-Tocco
5-Aza-2'-deoxycytidine as inducer of differentiation and growth inhibition in mouse neuroblastoma cells.
Cell differentiation and development : the official journal of the International Society of Developmental Biologists 1989;27(1):47-55.
1988: A Guagliardi; M Moracci; Giuseppe Manco; M Rossi; Simonetta Bartolucci
Oxalacetate decarboxylase and pyruvate carboxylase activities, and effect of sulfhydryl reagents in malic enzyme from Sulfolobus solfataricus.
Biochimica et biophysica acta 1988;957(2):301-11.
1987: Simonetta Bartolucci; R Rella; A Guagliardi; Carlo Antonio Raia; A Gambacorta; M De Rosa; M Rossi
Malic enzyme from archaebacterium Sulfolobus solfataricus. Purification, structure, and kinetic properties.
The Journal of biological chemistry 1987;262(16):7725-31.
1986: Richard L Momparler; M Rossi; J Bouchard; Simonetta Bartolucci; Louise F Momparler; Carlo Antonio Raia; Roberto Nucci; C Vaccaro; S Sepe
5-AZA-2'-deoxycytidine synergistic action with thymidine on leukemic cells and interaction of 5-AZA-dCMP with dCMP deaminase.
Advances in experimental medicine and biology 1986;195 Pt B():157-63.
1984: Richard L Momparler; M Rossi; J Bouchard; C Vaccaro; Louise F Momparler; Simonetta Bartolucci
Kinetic interaction of 5-AZA-2'-deoxycytidine-5'-monophosphate and its 5'-triphosphate with deoxycytidylate deaminase.
Molecular pharmacology 1984;25(3):436-40.