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Michael Maes

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Michael Maes; Frank N M Twisk; Cort Johnson
Myalgic Encephalomyelitis (ME), Chronic Fatigue Syndrome (CFS), and Chronic Fatigue (CF) are distinguished accurately: results of supervised learning techniques applied on clinical and inflammatory data.
Michael Maes; Ivana Mihaylova; Frank N M Twisk; Marta Kubera; Jean-Claude Leunis; Michel Geffard
IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) than in major depression.
Michael Maes; Marta Kubera; Jean-Claude Leunis; Michael Berk
Increased IgA and IgM responses against gut commensals in chronic depression: further evidence for increased bacterial translocation or leaky gut.

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2012: Michael Maes; Frank N M Twisk; Cort Johnson
Myalgic Encephalomyelitis (ME), Chronic Fatigue Syndrome (CFS), and Chronic Fatigue (CF) are distinguished accurately: results of supervised learning techniques applied on clinical and inflammatory data.
Psychiatry research 2012;200(2-3):754-60.
2012: Michael Maes; Ivana Mihaylova; Frank N M Twisk; Marta Kubera; Jean-Claude Leunis; Michel Geffard
IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) than in major depression.
Metabolic brain disease 2012;27(4):415-23.
2012: Michael Maes; Marta Kubera; Jean-Claude Leunis; Michael Berk
Increased IgA and IgM responses against gut commensals in chronic depression: further evidence for increased bacterial translocation or leaky gut.
Journal of affective disorders 2012;141(1):55-62.
2012: Michael Maes; Karl Ringel; Michael Berk; Marta Kubera; Janusz Rybakowski
Increased autoimmune activity against 5-HT: a key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression.
Journal of affective disorders 2012;136(3):386-92.
2012: Michael Maes; Marta Kubera; Frank N M Twisk; Karl Ringel
Evidence for inflammation and activation of cell-mediated immunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): increased interleukin-1, tumor necrosis factor-α, PMN-elastase, lysozyme and neopterin.
Journal of affective disorders 2012;136(3):933-9.
2012: Michael Maes; Karl Ringel; Frank N M Twisk; Marta Kubera; Jean-Claude Leunis; Michel Geffard
Increased IgA responses to the LPS of commensal bacteria is associated with inflammation and activation of cell-mediated immunity in chronic fatigue syndrome.
Journal of affective disorders 2012;136(3):909-17.
2012: Michael Maes; Ivana Mihaylova; Marta Kubera; Karl Ringel
Activation of cell-mediated immunity in depression: association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression.
Progress in neuro-psychopharmacology & biological psychiatry 2012;36(1):169-75.
2011: Michael Maes; Ivana Mihaylova; Marta Kubera; Jean-Claude Leunis; Michel Geffard
IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: new pathways that underpin the inflammatory and neuroprogressive pathophysiology.
Journal of affective disorders 2011;135(1-3):414-8.
2011: Michael Maes; Piotr Galecki; Robert Verkerk; Winfried Rief
Somatization, but not depression, is characterized by disorders in the tryptophan catabolite (TRYCAT) pathway, indicating increased indoleamine 2,3-dioxygenase and lowered kynurenine aminotransferase activity.
Neuro endocrinology letters 2011;32(3):264-73.
2010: Jan Croonenberghs; Sarah Van Grieken; Annick Wauters; Dirk Van West; Lucas Brouw; Michael Maes; Dirk Deboutte
Serum testosterone concentration in male autistic youngsters.
Neuro endocrinology letters 2010;31(4):483-8.
2008: Michael Maes; Jean-Claude Leunis
Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria.
Neuro endocrinology letters 2008;29(6):902-10.
2008: Michael Maes; Ivana Mihaylova; Marta Kubera; Jean-Claude Leunis
An IgM-mediated immune response directed against nitro-bovine serum albumin (nitro-BSA) in chronic fatigue syndrome (CFS) and major depression: evidence that nitrosative stress is another factor underpinning the comorbidity between major depression and CFS.
Neuro endocrinology letters 2008;29(3):313-9.
2008: Jan Croonenberghs; Kristien Spaas; Annick Wauters; Robert Verkerk; Simon Scharpe; Dirk Deboutte; Michael Maes
Faulty serotonin--DHEA interactions in autism: results of the 5-hydroxytryptophan challenge test.
Neuro endocrinology letters 2008;29(3):385-90.
2008: Michael Maes; Marta Kubera; Jean-Claude Leunis
The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression.
Neuro endocrinology letters 2008;29(1):117-24.
2007: Michael Maes; Ivana Mihaylova; Jean-Claude Leunis
Increased serum IgM antibodies directed against phosphatidyl inositol (Pi) in chronic fatigue syndrome (CFS) and major depression: evidence that an IgM-mediated immune response against Pi is one factor underpinning the comorbidity between both CFS and depression.
Neuro endocrinology letters 2007;28(6):861-7.
2007: Michael Maes; Francis Coucke; Jean-Claude Leunis
Normalization of the increased translocation of endotoxin from gram negative enterobacteria (leaky gut) is accompanied by a remission of chronic fatigue syndrome.
Neuro endocrinology letters 2007;28(6):739-44.
2007: Michael Maes; Ivana Mihaylova; Marcel De Ruyter; Marta Kubera; Eugene Bosmans
The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation.
Neuro endocrinology letters 2007;28(6):826-31.
2007: Michael Maes; Ivana Mihaylova; Marta Kubera; Eugene Bosmans
Why fish oils may not always be adequate treatments for depression or other inflammatory illnesses: docosahexaenoic acid, an omega-3 polyunsaturated fatty acid, induces a Th-1-like immune response.
Neuro endocrinology letters 2007;28(6):875-80.
2007: Marlies A van Duinen; Koen Schruers; Michael Maes; Eric Griez
CO2 challenge induced HPA axis activation in panic.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2007;10(6):797-804.
2007: Jan Croonenberghs; Annick Wauters; Dirk Deboutte; Robert Verkerk; Simon Scharpe; Michael Maes
Central serotonergic hypofunction in autism: results of the 5-hydroxy-tryptophan challenge test.
Neuro endocrinology letters 2007;28(4):449-55.
2007: Michael Maes; Ivana Mihaylova; Eugene Bosmans
Not in the mind of neurasthenic lazybones but in the cell nucleus: patients with chronic fatigue syndrome have increased production of nuclear factor kappa beta.
Neuro endocrinology letters 2007;28(4):456-62.
2007: Michael Maes; Ivana Mihaylova; Marta Kubera; Eugene Bosmans
Not in the mind but in the cell: increased production of cyclo-oxygenase-2 and inducible NO synthase in chronic fatigue syndrome.
Neuro endocrinology letters 2007;28(4):463-9.
2007: Ivana Mihaylova; Marcel DeRuyter; Jean-Luc Rummens; Eugene Bosmans; Michael Maes
Decreased expression of CD69 in chronic fatigue syndrome in relation to inflammatory markers: evidence for a severe disorder in the early activation of T lymphocytes and natural killer cells.
Neuro endocrinology letters 2007;28(4):477-83.
2007: Michael Maes; Ivana Mihaylova; Jean-Claude Leunis
Increased serum IgA and IgM against LPS of enterobacteria in chronic fatigue syndrome (CFS): indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut-intestinal permeability.
Journal of affective disorders 2007;99(1-3):237-40.
2007: Marieke C Wichers; Gunter Kenis; Ger H Koek; Geert Robaeys; Nancy Nicolson; Michael Maes
Interferon-alpha-induced depressive symptoms are related to changes in the cytokine network but not to cortisol.
Journal of psychosomatic research 2007;62(2):207-14.
2006: Michael Maes; Ivana Mihaylova; Jean-Claude Leunis
Chronic fatigue syndrome is accompanied by an IgM-related immune response directed against neopitopes formed by oxidative or nitrosative damage to lipids and proteins.
Neuro endocrinology letters 2006;27(5):615-21.
2006: Sonja Sliwinski; Jan Croonenberghs; Armand Christophe; Dirk Deboutte; Michael Maes
Polyunsaturated fatty acids: do they have a role in the pathophysiology of autism?
Neuro endocrinology letters 2006;27(4):465-71.
2006: Marieke C Wichers; Gunter Kenis; Carsten Leue; Ger H Koek; Geert Robaeys; Michael Maes
Baseline immune activation as a risk factor for the onset of depression during interferon-alpha treatment.
Biological psychiatry 2006;60(1):77-9.
2005: Michael Maes; Ivana Mihaylova; Jean-Claude Leunis
In chronic fatigue syndrome, the decreased levels of omega-3 poly-unsaturated fatty acids are related to lowered serum zinc and defects in T cell activation.
Neuro endocrinology letters 2005;26(6):745-51.
2005: Marieke C Wichers; Ger H Koek; Geert Robaeys; Robert Verkerk; Simon Scharpé; Michael Maes
IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity.
Molecular psychiatry 2005;10(6):538-44.
2005: Marlies A van Duinen; Koen Schruers; Michael Maes; Eric Griez
CO2 challenge results in hypothalamic-pituitary-adrenal activation in healthy volunteers.
Journal of psychopharmacology (Oxford, England) 2005;19(3):243-7.
2005: Jan Croonenberghs; Robert Verkerk; Simon Scharpe; Dirk Deboutte; Michael Maes
Serotonergic disturbances in autistic disorder: L-5-hydroxytryptophan administration to autistic youngsters increases the blood concentrations of serotonin in patients but not in controls.
Life sciences 2005;76(19):2171-83.
2005: Marieke C Wichers; Ger H Koek; Geert Robaeys; A J Praamstra; Michael Maes
Early increase in vegetative symptoms predicts IFN-alpha-induced cognitive-depressive changes.
Psychological medicine 2005;35(3):433-41.
2005: Michael Maes; Gunter Kenis; Marta Kubera; marc de baets; Harry W M Steinbusch; Eugene Bosmans
The negative immunoregulatory effects of fluoxetine in relation to the cAMP-dependent PKA pathway.
International immunopharmacology 2005;5(3):609-18.
2005: Annique Schins; Schins Annique; Dorien Tulner; Tulner Dorien; Richel Lousberg; Lousberg Richel; Gunter Kenis; Kenis Gunter; Joris Delanghe; Delanghe Joris; Harry J G M Crijns; J Crijns Harry; Gert Grauls; Grauls Gert; Frank R M Stassen; Stassen Frank; Michael Maes; Maes Michael; Adriaan Honig; Honig Adriaan
Inflammatory markers in depressed post-myocardial infarction patients.
Journal of psychiatric research 2005;39(2):137-44.
2005: Olga J G Schiepers; Marieke C Wichers; Michael Maes
Cytokines and major depression.
Progress in neuro-psychopharmacology & biological psychiatry 2005;29(2):201-17.
2004: Marlies A van Duinen; Koen Schruers; Erika Jaegers; Michael Maes; Eric Griez
Salivary cortisol in panic: are males more vulnerable?
Neuro endocrinology letters 2004;25(5):386-90.
2004: Jacqueline J M H Strik; Richel Lousberg; Harry J G M Crijns; Michael Maes; Adriaan Honig
Reply to a reader's comment.
The American journal of cardiology 2004;94(4):542.
2004: T O C Kilkens; Adriaan Honig; Michael Maes; Richel Lousberg; Robert-Jan M Brummer
Fatty acid profile and affective dysregulation in irritable bowel syndrome.
Lipids 2004;39(5):425-31.
2004: Marlies A van Duinen; Koen Schruers; Erika Jaegers; Michael Maes; Eric Griez
Hypothalamic-pituitary-adrenal axis function following a 35% CO2 inhalation in healthy volunteers.
Progress in neuro-psychopharmacology & biological psychiatry 2004;28(2):279-83.
2004: Michael Maes; S Bonaccorso
Lower activities of serum peptidases predict higher depressive and anxiety levels following interferon-alpha-based immunotherapy in patients with hepatitis C.
Acta psychiatrica Scandinavica 2004;109(2):126-31.
2004: Sjacko Sobczak; Adriaan Honig; Armand Christophe; Michael Maes; R W C Helsdingen; S A De Vriese; Wim J Riedel
Lower high-density lipoprotein cholesterol and increased omega-6 polyunsaturated fatty acids in first-degree relatives of bipolar patients.
Psychological medicine 2004;34(1):103-12.
2004: Michael Maes; Eugene Bosmans; Willem Ombelet
In the puerperium, primiparae exhibit higher levels of anxiety and serum peptidase activity and greater immune responses than multiparae.
The Journal of clinical psychiatry 2004;65(1):71-6.
2004: Winfried Rief; Florian Pilger; Daniel Ihle; Robert Verkerk; Simon Scharpe; Michael Maes
Psychobiological aspects of somatoform disorders: contributions of monoaminergic transmitter systems.
Neuropsychobiology 2004;49(1):24-9.
2004: Marieke C Wichers; Michael Maes
The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-alpha-induced depression.
Journal of psychiatry & neuroscience : JPN 2004;29(1):11-7.
2003: Stefania Bonaccorso; Steven F Maier; Herbert Y Meltzer; Michael Maes
Behavioral changes in rats after acute, chronic and repeated administration of interleukin-1beta: relevance for affective disorders.
Journal of affective disorders 2003;77(2):143-8.
2003: Charlotte E Teunissen; Dieter Lütjohann; Klaus Von Bergmann; Frans Verhey; Fred Vreeling; A Wauters; Eugene Bosmans; H Bosma; Martin van Boxtel; Michael Maes; J Delanghe; H J Blom; M M Verbeek; P Rieckmann; Chris de Bruijn; Harry W M Steinbusch; Jan de Vente
Combination of serum markers related to several mechanisms in Alzheimer's disease.
Neurobiology of aging 2003;24(7):893-902.
2003: Marie Jeanne Haack; M L F J Bak; Rob Beurskens; Michael Maes; L M L Stolk; Philippe A E G Delespaul
Toxic rise of clozapine plasma concentrations in relation to inflammation.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(5):381-5.
2003: Andre J A M van der Ven; Rob van Diest; Karly Hamulyák; Michael Maes; Cathrien Bruggeman; Ad Appels
Herpes viruses, cytokines, and altered hemostasis in vital exhaustion.
Psychosomatic medicine 2003;65(2):194-200.
2003: Charlotte E Teunissen; Martin van Boxtel; H Bosma; Jelle Jolles; Dieter Lütjohann; Klaus Von Bergmann; A Wauters; Eugene Bosmans; Michael Maes; J Delanghe; Chris de Bruijn; Harry W M Steinbusch; H J Blom; Jan de Vente
[Serum markers in relation to cognitive functioning in an aging population: results of the Maastricht Aging Study (MAAS)].
Tijdschrift voor gerontologie en geriatrie 2003;34(1):6-12.
2003: Charlotte E Teunissen; Martin van Boxtel; H Bosma; Eugene Bosmans; J Delanghe; Chris de Bruijn; A Wauters; Michael Maes; Jelle Jolles; Harry W M Steinbusch; Jan de Vente
Inflammation markers in relation to cognition in a healthy aging population.
Journal of neuroimmunology 2003;134(1-2):142-50.
2003: Gunter Kenis; Harry W M Steinbusch; Marc H De Baets; Michael Maes
Influence of antidepressants on intracellular levels of cyclic adenosine monophosphate in human peripheral blood mononuclear cells.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(1):53-6.
2002: Jacqueline J M H Strik; Richel Lousberg; Harry J G M Crijns; Michael Maes; Adriaan Honig
Relation of levels of serum lipoproteins to depression after acute myocardial infarction.
The American journal of cardiology 2002;90(12):1368-70.
2002: Gunter Kenis; Michael Maes
Effects of antidepressants on the production of cytokines.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2002;5(4):401-12.
2002: Marieke C Wichers; Michael Maes
The psychoneuroimmuno-pathophysiology of cytokine-induced depression in humans.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2002;5(4):375-88.
2002: Michael Maes
Introduction to the special section.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2002;5(4):329-31.
2002: Stefania Bonaccorso; Valentina Marino; Massimo Biondi; Franca Grimaldi; Flora Ippoliti; Michael Maes
Depression induced by treatment with interferon-alpha in patients affected by hepatitis C virus.
Journal of affective disorders 2002;72(3):237-41.
2002: Jan Croonenberghs; Annick Wauters; Katrien Devreese; Robert Verkerk; Simon Scharpe; Eugene Bosmans; B Egyed; Dirk Deboutte; Michael Maes
Increased serum albumin, gamma globulin, immunoglobulin IgG, and IgG2 and IgG4 in autism.
Psychological medicine 2002;32(8):1457-63.
2002: Michael Maes; Gunter Kenis; Eugene Bosmans
The negative immunoregulatory effects of serotonin (5-HT) moduline, an endogenous 5-HT1B receptor antagonist with anti-anxiety properties.
Cytokine 2002;19(6):308-11.
2002: Gunter Kenis; Charlotte E Teunissen; Raf F de Jongh; Eugene Bosmans; Harry W M Steinbusch; Michael Maes
Stability of interleukin 6, soluble interleukin 6 receptor, interleukin 10 and CC16 in human serum.
Cytokine 2002;19(5):228-35.
2002: Michael Maes; Robert Verkerk; Stefania Bonaccorso; Willem Ombelet; Eugene Bosmans; Simon Scharpé
Depressive and anxiety symptoms in the early puerperium are related to increased degradation of tryptophan into kynurenine, a phenomenon which is related to immune activation.
Life sciences 2002;71(16):1837-48.
2002: Sjacko Sobczak; Adriaan Honig; Marlies A van Duinen; Michael Maes; Wim J Riedel
Mood, prolactin and cortisol responses following intravenous L-tryptophan challenge: evidence for serotonergic vulnerability in first-degree relatives of bipolar patients.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2002;5(3):249-54.
2002: Michael Maes; A Van Gastel; L Delmeire; Gunter Kenis; Eugene Bosmans; C Song
Platelet alpha2-adrenoceptor density in humans: relationships to stress-induced anxiety, psychasthenic constitution, gender and stress-induced changes in the inflammatory response system.
Psychological medicine 2002;32(5):919-28.
2002: Michael Maes; Luisella Bocchio Chiavetto; Stefano Bignotti; Giani-Jean Battisa Tura; Rosaria Pioli; Francesco Boin; Gunter Kenis; Eugene Bosmans; Raf F de Jongh; Carlo A Altamura
Increased serum interleukin-8 and interleukin-10 in schizophrenic patients resistant to treatment with neuroleptics and the stimulatory effects of clozapine on serum leukemia inhibitory factor receptor.
Schizophrenia research 2002;54(3):281-91.
2002: Stefania Bonaccorso; Valentina Marino; Antonella Puzella; Massimo Pasquini; Massimo Biondi; Marco Artini; Cristiana Almerighi; Robert Verkerk; Herbert Y Meltzer; Michael Maes
Increased depressive ratings in patients with hepatitis C receiving interferon-alpha-based immunotherapy are related to interferon-alpha-induced changes in the serotonergic system.
Journal of clinical psychopharmacology 2002;22(1):86-90.
2002: Lucile Capuron; Alain Ravaud; Pierre J Neveu; Andrew H Miller; Michael Maes; Robert Dantzer
Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy.
Molecular psychiatry 2002;7(5):468-73.
2002: Jan Croonenberghs; Eugene Bosmans; Dirk Deboutte; Gunter Kenis; Michael Maes
Activation of the inflammatory response system in autism.
Neuropsychobiology 2002;45(1):1-6.
2001: Winfried Rief; Florian Pilger; Daniel Ihle; Eugene Bosmans; B Egyed; Michael Maes
Immunological differences between patients with major depression and somatization syndrome.
Psychiatry research 2001;105(3):165-74.
2001: Stefania Bonaccorso; Antonella Puzella; Valentina Marino; Massimo Pasquini; Massimo Biondi; Marco Artini; Cristiana Almerighi; Massimo Levrero; B Egyed; Eugene Bosmans; Herbert Y Meltzer; Michael Maes
Immunotherapy with interferon-alpha in patients affected by chronic hepatitis C induces an intercorrelated stimulation of the cytokine network and an increase in depressive and anxiety symptoms.
Psychiatry research 2001;105(1-2):45-55.
2001: Michael Maes; J Mylle; L Delmeire; A Janca
Pre- and post-disaster negative life events in relation to the incidence and severity of post-traumatic stress disorder.
Psychiatry research 2001;105(1-2):1-12.
2001: Lucile Capuron; Alain Ravaud; Norbert Gualde; Eugene Bosmans; Robert Dantzer; Michael Maes; Pierre J Neveu
Association between immune activation and early depressive symptoms in cancer patients treated with interleukin-2-based therapy.
Psychoneuroendocrinology 2001;26(8):797-808.
2001: Michael Maes; J Delanghe; Luisella Bocchio Chiavetto; Stefano Bignotti; Gian Battista Tura; Rosaria Pioli; Roberta Zanardini; Carlo A Altamura
Haptoglobin polymorphism and schizophrenia: genetic variation on chromosome 16.
Psychiatry research 2001;104(1):1-9.
2001: Michael Maes; N De Vos; F Van Hunsel; Dirk van West; Herman G M Westenberg; P Cosyns; Hugo Neels
Pedophilia is accompanied by increased plasma concentrations of catecholamines, in particular epinephrine.
Psychiatry research 2001;103(1):43-9.
2001: Michael Maes; Willem Ombelet; Robert Verkerk; Eugene Bosmans; Simon Scharpé
Effects of pregnancy and delivery on the availability of plasma tryptophan to the brain: relationships to delivery-induced immune activation and early post-partum anxiety and depression.
Psychological medicine 2001;31(5):847-58.
2001: Michael Maes; Stefania Bonaccorso; Valentina Marino; Antonella Puzella; Massimo Pasquini; Massimo Biondi; Marco Artini; Cristiana Almerighi; Herbert Y Meltzer
Treatment with interferon-alpha (IFN alpha) of hepatitis C patients induces lower serum dipeptidyl peptidase IV activity, which is related to IFN alpha-induced depressive and anxiety symptoms and immune activation.
Molecular psychiatry 2001;6(4):475-80.
2001: Jacqueline J M H Strik; Adriaan Honig; Michael Maes
Depression and myocardial infarction: relationship between heart and mind.
Progress in neuro-psychopharmacology & biological psychiatry 2001;25(4):879-92.
2001: Ivo Aben; Frans Verhey; Adriaan Honig; Jan Lodder; Richel Lousberg; Michael Maes
Research into the specificity of depression after stroke: a review on an unresolved issue.
Progress in neuro-psychopharmacology & biological psychiatry 2001;25(4):671-89.
2001: Marta Kubera; AH Lin; Gunter Kenis; Eugene Bosmans; D van Bockstaele; Michael Maes
Anti-Inflammatory effects of antidepressants through suppression of the interferon-gamma/interleukin-10 production ratio.
Journal of clinical psychopharmacology 2001;21(2):199-206.
2001: Michael Maes; L Delmeire; J Mylle; Carlo A Altamura
Risk and preventive factors of post-traumatic stress disorder (PTSD): alcohol consumption and intoxication prior to a traumatic event diminishes the relative risk to develop PTSD in response to that trauma.
Journal of affective disorders 2001;63(1-3):113-21.
2001: Michael Maes; Willem Ombelet; Raf F de Jongh; Gunter Kenis; Eugene Bosmans
The inflammatory response following delivery is amplified in women who previously suffered from major depression, suggesting that major depression is accompanied by a sensitization of the inflammatory response system.
Journal of affective disorders 2001;63(1-3):85-92.
2001: Michael Maes; Lucile Capuron; A Ravaud; Norbert Gualde; Eugene Bosmans; B Egyed; Robert Dantzer; Pierre J Neveu
Lowered serum dipeptidyl peptidase IV activity is associated with depressive symptoms and cytokine production in cancer patients receiving interleukin-2-based immunotherapy.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;24(2):130-40.
2001: Francesco Boin; Roberta Zanardini; Rosaria Pioli; Carlo A Altamura; Michael Maes; Massimo Gennarelli
Association between -G308A tumor necrosis factor alpha gene polymorphism and schizophrenia.
Molecular psychiatry 2001;6(1):79-82.
2001: Michael Maes; Dirk van West; D Nuyten; Hugo Neels; N De Vos; S De Bruyne; J Degroote
The prolonged P(300) latency in recently detoxified alcohol-dependent patients is related to activation of the inflammatory response system.
Neuropsychobiology 2001;43(2):63-9.
2001: Michael Maes; Dirk van West; N De Vos; Herman G M Westenberg; F Van Hunsel; D Hendriks; P Cosyns; Simon Scharpé
Lower baseline plasma cortisol and prolactin together with increased body temperature and higher mCPP-induced cortisol responses in men with pedophilia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;24(1):37-46.
2001: Michael Maes; Palmiero Monteleone; Rachele Bencivenga; Filip Goossens; Mario Maj; Dirk van West; Eugene Bosmans; Simon Scharpe
Lower serum activity of prolyl endopeptidase in anorexia and bulimia nervosa.
Psychoneuroendocrinology 2001;26(1):17-26.
2000: Michael Maes; Robert Verkerk; L Delmeire; A Van Gastel; F Van Hunsel; Simon Scharpé
Serotonergic markers and lowered plasma branched-chain-amino acid concentrations in fibromyalgia.
Psychiatry research 2000;97(1):11-20.
2000: Michael Maes; A Lin; G Kenis; B Egyed; Eugene Bosmans
The effects of noradrenaline and alpha-2 adrenoceptor agents on the production of monocytic products.
Psychiatry research 2000;96(3):245-53.
2000: Marta Kubera; Gunter Kenis; Eugene Bosmans; Simon Scharpé; Michael Maes
Effects of serotonin and serotonergic agonists and antagonists on the production of interferon-gamma and interleukin-10.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;23(1):89-98.
2000: Michael Maes; N De Vos; Rosaria Pioli; P Demedts; Annick Wauters; Hugo Neels; Armand Christophe
Lower serum vitamin E concentrations in major depression. Another marker of lowered antioxidant defenses in that illness.
Journal of affective disorders 2000;58(3):241-6.
2000: Michael Maes; Armand Christophe; Eugene Bosmans; A Lin; Hugo Neels
In humans, serum polyunsaturated fatty acid levels predict the response of proinflammatory cytokines to psychologic stress.
Biological psychiatry 2000;47(10):910-20.
2000: A h Lin; C Song; Gunter Kenis; Eugene Bosmans; Raf F de Jongh; Simon Scharpé; Michael Maes
The in vitro immunosuppressive effects of moclobemide in healthy volunteers.
Journal of affective disorders 2000;58(1):69-74.
2000: Michael Maes; Luisella Bocchio Chiavetto; Stefano Bignotti; G Battisa Tura; Rosaria Pioli; Francesco Boin; Gunter Kenis; Eugene Bosmans; Raf F de Jongh; A h Lin; Giorgio Racagni; Carlo A Altamura
Effects of atypical antipsychotics on the inflammatory response system in schizophrenic patients resistant to treatment with typical neuroleptics.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2000;10(2):119-24.
2000: Jan Croonenberghs; L Delmeire; Robert Verkerk; AH Lin; A Meskal; Hugo Neels; Marc van der Planken; Simon Scharpe; Dirk Deboutte; G Pison; Michael Maes
Peripheral markers of serotonergic and noradrenergic function in post-pubertal, caucasian males with autistic disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(3):275-83.
2000: Michael Maes; E Vandoolaeghe; J Degroote; Carlo A Altamura; C Roels; P Hermans
Linear CT-scan measurements in alcohol-dependent patients with and without delirium tremens.
Alcohol (Fayetteville, N.Y.) 2000;20(2):117-23.
2000: Michael Maes; AH Lin; Willem Ombelet; K Stevens; Gunter Kenis; Raf F de Jongh; J Cox; Eugene Bosmans
Immune activation in the early puerperium is related to postpartum anxiety and depressive symptoms.
Psychoneuroendocrinology 2000;25(2):121-37.
2000: Michael Maes; J Mylle; L Delmeire; Carlo A Altamura
Psychiatric morbidity and comorbidity following accidental man-made traumatic events: incidence and risk factors.
European archives of psychiatry and clinical neuroscience 2000;250(3):156-62.
2000: Dirk van West; Palmiero Monteleone; A Di Lieto; Ingrid De Meester; Christine Durinx; Simon Scharpe; A h Lin; Mario Maj; Michael Maes
Lowered serum dipeptidyl peptidase IV activity in patients with anorexia and bulimia nervosa.
European archives of psychiatry and clinical neuroscience 2000;250(2):86-92.
2000: Michael Maes; I Libbrecht; A h Lin; Filip Goossens; Willem Ombelet; K Stevens; Eugene Bosmans; Carlo A Altamura; J Cox; Raf F de Jongh; Simon Scharpé
Effects of pregnancy and delivery on serum prolyl endopeptidase (PEP) activity: alterations in serum PEP are related to increased anxiety in the early puerperium and to postpartum depression.
Journal of affective disorders 2000;57(1-3):125-37.
1999: Michael Maes; N De Vos; P Demedts; Annick Wauters; Hugo Neels
Lower serum zinc in major depression in relation to changes in serum acute phase proteins.
Journal of affective disorders 1999;56(2-3):189-94.
1999: Michael Maes; N DeVos; Annick Wauters; P Demedts; V W Maurits; Hugo Neels; Eugene Bosmans; Carlo A Altamura; A h Lin; C Song; M Vandenbroucke; Simon Scharpe
Inflammatory markers in younger vs elderly normal volunteers and in patients with Alzheimer's disease.
Journal of psychiatric research 1999;33(5):397-405.
1999: Michael Maes; I Libbrecht; L Delmeire; A h Lin; Luc S De Clerck; Simon Scharpe; A Janca
Changes in platelet alpha-2-adrenoceptors in fibromyalgia: effects of treatment with antidepressants.
Neuropsychobiology 1999;40(3):129-33.
1999: Michael Maes; I Libbrecht; F Van Hunsel; AH Lin; Luc S De Clerck; Wim Stevens; Gunter Kenis; Raf F de Jongh; Eugene Bosmans; Hugo Neels
The immune-inflammatory pathophysiology of fibromyalgia: increased serum soluble gp130, the common signal transducer protein of various neurotrophic cytokines.
Psychoneuroendocrinology 1999;24(4):371-83.
1999: C Song; A h Lin; R De Jong; E Vandoolaeghe; Gunter Kenis; Eugene Bosmans; A Whelan; Simon Scharpe; Michael Maes
Cytokines in detoxified patients with chronic alcoholism without liver disease: increased monocytic cytokine production.
Biological psychiatry 1999;45(9):1212-6.
1999: Michael Maes; C Song; AH Lin; Rosaria Pioli; Gunter Kenis; Marta Kubera; Eugene Bosmans
In vitro immunoregulatory effects of lithium in healthy volunteers.
Psychopharmacology 1999;143(4):401-7.
1999: Carlo A Altamura; A VanGastel; Rosaria Pioli; P Mannu; Michael Maes
Seasonal and circadian rhythms in suicide in Cagliari, Italy.
Journal of affective disorders 1999;53(1):77-85.
1999: Michael Maes; AH Lin; Stefania Bonaccorso; Filip Goossens; A Van Gastel; Rosaria Pioli; L Delmeire; Simon Scharpé
Higher serum prolyl endopeptidase activity in patients with post-traumatic stress disorder.
Journal of affective disorders 1999;53(1):27-34.
1999: Michael Maes; I Libbrecht; F Van Hunsel; D Campens; Herbert Y Meltzer
Pindolol and mianserin augment the antidepressant activity of fluoxetine in hospitalized major depressed patients, including those with treatment resistance.
Journal of clinical psychopharmacology 1999;19(2):177-82.
1999: Michael Maes; AH Lin; L Delmeire; A Van Gastel; Gunter Kenis; Raf F de Jongh; Eugene Bosmans
Elevated serum interleukin-6 (IL-6) and IL-6 receptor concentrations in posttraumatic stress disorder following accidental man-made traumatic events.
Biological psychiatry 1999;45(7):833-9.
1999: Michael Maes; C Song; AH Lin; Stefania Bonaccorso; Gunter Kenis; Raf F de Jongh; Eugene Bosmans; Simon Scharpé
Negative immunoregulatory effects of antidepressants: inhibition of interferon-gamma and stimulation of interleukin-10 secretion.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(4):370-9.
1999: C Song; Gunter Kenis; A Van Gastel; Eugene Bosmans; A h Lin; R De Jong; Hugo Neels; Simon Scharpé; A Janca; K Yasukawa; Michael Maes
Influence of psychological stress on immune-inflammatory variables in normal humans. Part II. Altered serum concentrations of natural anti-inflammatory agents and soluble membrane antigens of monocytes and T lymphocytes.
Psychiatry research 1999;85(3):293-303.
1999: Michael Maes; Armand Christophe; Joris Delanghe; Carlo A Altamura; Hugo Neels; Herbert Y Meltzer
Lowered omega3 polyunsaturated fatty acids in serum phospholipids and cholesteryl esters of depressed patients.
Psychiatry research 1999;85(3):275-91.
1999: Michael Maes; A Van Gastel; L Delmeire; Herbert Y Meltzer
Decreased platelet alpha-2 adrenoceptor density in major depression: effects of tricyclic antidepressants and fluoxetine.
Biological psychiatry 1999;45(3):278-84.
1999: Michael Maes; AH Lin; Robert Verkerk; L Delmeire; A Van Gastel; Marc van der Planken; Simon Scharpé
Serotonergic and noradrenergic markers of post-traumatic stress disorder with and without major depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(2):188-97.
1999: C Song; M Vandewoude; Wim Stevens; Luc S De Clerck; Marc van der Planken; A Whelan; H Anisman; A Dossche; Michael Maes
Alterations in immune functions during normal aging and Alzheimer's disease.
Psychiatry research 1999;85(1):71-80.
1999: N De Vos; C Song; A h Lin; P Demedts; Annick Wauters; Hugo Neels; Raf F de Jongh; Gunter Kenis; Eugene Bosmans; Carlo A Altamura; Michael Maes
Lower serum zinc in relation to serum albumin and proinflammatory cytokines in detoxified alcohol-dependent patients without apparent liver disease.
Neuropsychobiology 1999;39(3):144-50.
1999: Michael Maes; A h Lin; Stefania Bonaccorso; E Vandoolaeghe; C Song; Filip Goossens; Ingrid De Meester; J Degroote; Hugo Neels; Simon Scharpé; A Janca
Lower activity of serum peptidases in abstinent alcohol-dependent patients.
Alcohol (Fayetteville, N.Y.) 1999;17(1):1-6.
1999: Michael Maes; D R Van Bockstaele; A Gastel; C Song; chris schotte; Hugo Neels; I DeMeester; Simon Scharpe; A Janca
The effects of psychological stress on leukocyte subset distribution in humans: evidence of immune activation.
Neuropsychobiology 1999;39(1):1-9.
1998: Michael Maes; L Delmeire; chris schotte; A Janca; T Creten; J Mylle; A Struyf; G Pison; PJ Rousseeuw
The two-factorial symptom structure of post-traumatic stress disorder: depression-avoidance and arousal-anxiety.
Psychiatry research 1998;81(2):195-210.
1998: Michael Maes; L Delmeire; chris schotte; A Janca; T Creten; J Mylle; A Struyf; G Pison; PJ Rousseeuw
Epidemiologic and phenomenological aspects of post-traumatic stress disorder: DSM-III-R diagnosis and diagnostic criteria not validated.
Psychiatry research 1998;81(2):179-93.
1998: Michael Maes; A h Lin; Stefania Bonaccorso; F Van Hunsel; A Van Gastel; L Delmeire; Massimo Biondi; Eugene Bosmans; Gunter Kenis; Simon Scharpé
Increased 24-hour urinary cortisol excretion in patients with post-traumatic stress disorder and patients with major depression, but not in patients with fibromyalgia.
Acta psychiatrica Scandinavica 1998;98(4):328-35.
1998: Michael Maes; Marc van der Planken; A Van Gastel; K Bruyland; F Van Hunsel; Hugo Neels; D Hendriks; Annick Wauters; P Demedts; A Janca; Simon Scharpé
Influence of academic examination stress on hematological measurements in subjectively healthy volunteers.
Psychiatry research 1998;80(3):201-12.
1998: Stefania Bonaccorso; A h Lin; C Song; Robert Verkerk; Gunter Kenis; Eugene Bosmans; Simon Scharpe; M Vandewoude; A Dossche; Michael Maes
Serotonin-immune interactions in elderly volunteers and in patients with Alzheimer's disease (DAT): lower plasma tryptophan availability to the brain in the elderly and increased serum interleukin-6 in DAT.
Aging (Milan, Italy) 1998;10(4):316-23.
1998: Michael Maes; Filip Goossens; A h Lin; Ingrid De Meester; A Van Gastel; Simon Scharpé
Effects of psychological stress on serum prolyl endopeptidase and dipeptidyl peptidase IV activity in humans: higher serum prolyl endopeptidase activity is related to stress-induced anxiety.
Psychoneuroendocrinology 1998;23(5):485-95.
1998: Michael Maes; I Libbrecht; F Van Hunsel; AH Lin; Stefania Bonaccorso; Filip Goossens; Ingrid De Meester; Luc S De Clerck; Massimo Biondi; Simon Scharpe; A Janca
Lower serum activity of prolyl endopeptidase in fibromyalgia is related to severity of depressive symptoms and pressure hyperalgesia.
Psychological medicine 1998;28(4):957-65.
1998: A h Lin; Gunter Kenis; Stefano Bignotti; G J Tura; R De Jong; Eugene Bosmans; Rosaria Pioli; Carlo A Altamura; Simon Scharpé; Michael Maes
The inflammatory response system in treatment-resistant schizophrenia: increased serum interleukin-6.
Schizophrenia research 1998;32(1):9-15.
1998: C Song; A h Lin; Stefania Bonaccorso; C Heide; Robert Verkerk; Gunter Kenis; Eugene Bosmans; Simon Scharpe; A Whelan; P Cosyns; Raf F de Jongh; Michael Maes
The inflammatory response system and the availability of plasma tryptophan in patients with primary sleep disorders and major depression.
Journal of affective disorders 1998;49(3):211-9.
1998: Michael Maes; A h Lin; Eugene Bosmans; E Vandoolaeghe; Stefania Bonaccorso; Gunter Kenis; Raf F de Jongh; Robert Verkerk; C Song; Simon Scharpé; Hugo Neels
Serotonin-immune interactions in detoxified chronic alcoholic patients without apparent liver disease: activation of the inflammatory response system and lower plasma total tryptophan.
Psychiatry research 1998;78(3):151-61.
1998: Michael Maes; C Song; A h Lin; Raf F de Jongh; A Van Gastel; Gunter Kenis; Eugene Bosmans; Ingrid De Meester; I Benoy; Hugo Neels; P Demedts; A Janca; Simon Scharpé; R S Smith
The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety.
Cytokine 1998;10(4):313-8.
1998: Michael Maes; Robert Verkerk; E Vandoolaeghe; A h Lin; Simon Scharpé
Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity.
Acta psychiatrica Scandinavica 1998;97(4):302-8.
1998: F Van Hunsel; A Van Gastel; Hugo Neels; Annick Wauters; P Demedts; K Bruyland; I DeMeester; Simon Scharpé; A Janca; C Song; Michael Maes
The influence of psychological stress on total serum protein and patterns obtained in serum protein electrophoresis.
Psychological medicine 1998;28(2):301-9.
1998: E Vandoolaeghe; F Van Hunsel; D Nuyten; Michael Maes
Auditory event related potentials in major depression: prolonged P300 latency and increased P200 amplitude.
Journal of affective disorders 1998;48(2-3):105-13.
1998: Stefania Bonaccorso; AH Lin; Robert Verkerk; F Van Hunsel; I Libbrecht; Simon Scharpé; L DeClerck; Massimo Biondi; A Janca; Michael Maes
Immune markers in fibromyalgia: comparison with major depressed patients and normal volunteers.
Journal of affective disorders 1998;48(1):75-82.
1997: chris schotte; Michael Maes; R Cluydts; Dirk A M De Doncker; Paul Cosyns
Construct validity of the Beck Depression Inventory in a depressive population.
Journal of affective disorders 1997;46(2):115-25.
1997: Michael Maes; Eugene Bosmans; Raf F de Jongh; Gunter Kenis; E Vandoolaeghe; Hugo Neels
Increased serum IL-6 and IL-1 receptor antagonist concentrations in major depression and treatment resistant depression.
Cytokine 1997;9(11):853-8.
1997: A Van Gastel; chris schotte; Michael Maes
The prediction of suicidal intent in depressed patients.
Acta psychiatrica Scandinavica 1997;96(4):254-9.
1997: Michael Maes; H Westenberg; E Vandoolaeghe; P Demedts; Annick Wauters; Hugo Neels; Herbert Y Meltzer
Effects of trazodone and fluoxetine in the treatment of major depression: therapeutic pharmacokinetic and pharmacodynamic interactions through formation of meta-chlorophenylpiperazine.
Journal of clinical psychopharmacology 1997;17(5):358-64.
1997: Michael Maes; E Vandoolaeghe; Hugo Neels; P Demedts; Annick Wauters; Herbert Y Meltzer; Carlo A Altamura; R Desnyder
Lower serum zinc in major depression is a sensitive marker of treatment resistance and of the immune/inflammatory response in that illness.
Biological psychiatry 1997;42(5):349-58.
1997: Michael Maes; Eugene Bosmans; Gunter Kenis; R De Jong; R S Smith; Herbert Y Meltzer
In vivo immunomodulatory effects of clozapine in schizophrenia.
Schizophrenia research 1997;26(2-3):221-5.
1997: chris schotte; Michael Maes; R Cluydts; Paul Cosyns
Cluster analytic validation of the DSM melancholic depression. The threshold model: integration of quantitative and qualitative distinctions between unipolar depressive subtypes.
Psychiatry research 1997;71(3):181-95.
1997: Michael Maes; D Hendriks; A Van Gastel; P Demedts; Annick Wauters; Hugo Neels; A Janca; Simon Scharpé
Effects of psychological stress on serum immunoglobulin, complement and acute phase protein concentrations in normal volunteers.
Psychoneuroendocrinology 1997;22(6):397-409.
1997: Michael Maes; K Mommen; D Hendrickx; D Peeters; P D'Hondt; R Ranjan; F De Meyer; Simon Scharpé
Components of biological variation, including seasonality, in blood concentrations of TSH, TT3, FT4, PRL, cortisol and testosterone in healthy volunteers.
Clinical endocrinology 1997;46(5):587-98.
1997: E Vandoolaeghe; Michael Maes; J Vandevyvere; Hugo Neels
Hypothalamic-pituitary-thyroid-axis function in treatment resistant depression.
Journal of affective disorders 1997;43(2):143-50.
1997: Michael Maes; R Smith; Armand Christophe; E Vandoolaeghe; A Van Gastel; Hugo Neels; P Demedts; Annick Wauters; Herbert Y Meltzer
Lower serum high-density lipoprotein cholesterol (HDL-C) in major depression and in depressed men with serious suicidal attempts: relationship with immune-inflammatory markers.
Acta psychiatrica Scandinavica 1997;95(3):212-21.
1997: Michael Maes; Ingrid De Meester; Robert Verkerk; P De Medts; Annick Wauters; G Vanhoof; E Vandoolaeghe; Hugo Neels; Simon Scharpé
Lower serum dipeptidyl peptidase IV activity in treatment resistant major depression: relationships with immune-inflammatory markers.
Psychoneuroendocrinology 1997;22(2):65-78.
1997: Michael Maes; Eugene Bosmans; S Scharpé; D Hendriks; W Cooremans; Hugo Neels; F De Meyer; P D'Hondt; D Peeters
Components of biological variation in serum soluble transferrin receptor: relationships to serum iron, transferrin and ferritin concentrations, and immune and haematological variables.
Scandinavian journal of clinical and laboratory investigation 1997;57(1):31-41.
1997: Michael Maes; J Delange; R Ranjan; Herbert Y Meltzer; R Desnyder; W Cooremans; Simon Scharpé
Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs.
Psychiatry research 1997;66(1):1-11.
1997: Michael Maes; P Thompson
Analysis of partial variance to control for day-to-day variability in functional immune tests in depression.
Neuropsychobiology 1997;36(3):107-11.
1997: Michael Maes; Robert Verkerk; E Vandoolaeghe; F Van Hunsel; Hugo Neels; Annick Wauters; P Demedts; Simon Scharpé
Serotonin-immune interactions in major depression: lower serum tryptophan as a marker of an immune-inflammatory response.
European archives of psychiatry and clinical neuroscience 1997;247(3):154-61.
1996: F Van Hunsel; Annick Wauters; E Vandoolaeghe; Hugo Neels; P Demedts; Michael Maes
Lower total serum protein, albumin, and beta- and gamma-globulin in major and treatment-resistant depression: effects of antidepressant treatments.
Psychiatry research 1996;65(3):159-69.
1996: Michael Maes; E Vandoolaeghe; R Desnyder
Efficacy of treatment with trazodone in combination with pindolol or fluoxetine in major depression.
Journal of affective disorders 1996;41(3):201-10.
1996: Michael Maes; E Vandoolaeghe; R Ranjan; Eugene Bosmans; A Van Gastel; R Bergmans; R Desnyder
Increased serum soluble CD8 or suppressor/cytotoxic antigen concentrations in depression: suppressive effects of glucocorticoids.
Biological psychiatry 1996;40(12):1273-81.
1996: chris schotte; Michael Maes; R Cluydts; Paul Cosyns
Effects of affective-semantic mode of item presentation in balanced self-report scales: biased construct validity of the Zung Self-rating Depression Scale.
Psychological medicine 1996;26(6):1161-8.
1996: Michael Maes; S Weeckx; Annick Wauters; Hugo Neels; Simon Scharpé; Robert Verkerk; P Demedts; R Desnyder
Biological variability in serum vitamin E concentrations: relation to serum lipids.
Clinical chemistry 1996;42(11):1824-31.
1996: Michael Maes; Herbert Y Meltzer
Effects of meta-chlorophenylpiperazine on neuroendocrine and behavioral responses in male schizophrenic patients and normal volunteers.
Psychiatry research 1996;64(3):147-59.
1996: Michael Maes; A Van Gastel; R Ranjan; P Blockx; Paul Cosyns; Herbert Y Meltzer; R Desnyder
Stimulatory effects of L-5-hydroxytryptophan on postdexamethasone beta-endorphin levels in major depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(4):340-8.
1996: Michael Maes; Marc van der Planken; A Van Gastel; R Desnyder
Blood coagulation and platelet aggregation in major depression.
Journal of affective disorders 1996;40(1-2):35-40.
1996: Michael Maes; J Van de Vyvere; E Vandoolaeghe; T Bril; P Demedts; Annick Wauters; Hugo Neels
Alterations in iron metabolism and the erythron in major depression: further evidence for a chronic inflammatory process.
Journal of affective disorders 1996;40(1-2):23-33.
1996: Willem Ombelet; Michael Maes; H Vandeput; A Cox; M Janssen; H Pollet; F L Fourie; O Steeno; Eugene Bosmans
Chronobiological fluctuations in semen parameters with a constant abstinence period.
Archives of andrology 1996;37(2):91-6.
1996: Michael Maes; Annick Wauters; Robert Verkerk; P Demedts; Hugo Neels; A Van Gastel; Paul Cosyns; Simon Scharpé; R Desnyder
Lower serum L-tryptophan availability in depression as a marker of a more generalized disorder in protein metabolism.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(3):243-51.
1996: P D'Hondt; Michael Maes; Josée E Leysen; W Gommeren; L Heylen; F DeMeyer; Simon Scharpe; D Peeters; R Desnyder
Seasonal variation in platelet [3H]paroxetine binding in healthy volunteers. Relationship to climatic variables.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(2):187-98.
1996: Michael Maes; Eugene Bosmans; R Ranjan; E Vandoolaeghe; Herbert Y Meltzer; M De Ley; R Berghmans; G Stans; R Desnyder
Lower plasma CC16, a natural anti-inflammatory protein, and increased plasma interleukin-1 receptor antagonist in schizophrenia: effects of antipsychotic drugs.
Schizophrenia research 1996;21(1):39-50.
1996: Michael Maes; A Van Gastel; P Blockx; M Martin; Paul Cosyns; Simon Scharpé; R Ranjan; R Desnyder
Lower serum transcortin (CBG) in major depressed females: relationships with baseline and postdexamethasone cortisol values.
Journal of affective disorders 1996;38(1):47-56.
1996: Michael Maes; R Smith; A Christophe; Paul Cosyns; R Desnyder; Herbert Y Meltzer
Fatty acid composition in major depression: decreased omega 3 fractions in cholesteryl esters and increased C20: 4 omega 6/C20:5 omega 3 ratio in cholesteryl esters and phospholipids.
Journal of affective disorders 1996;38(1):35-46.
1996: Michael Maes; Simon Scharpé; P D'Hondt; D Peeters; Annick Wauters; Hugo Neels; Robert Verkerk
Biochemical, metabolic and immune correlates of seasonal variation in violent suicide: a chronoepidemiologic study.
European psychiatry : the journal of the Association of European Psychiatrists 1996;11(1):21-33.
1996: Herbert Y Meltzer; Michael Maes
Effect of pindolol on hormone secretion and body temperature: partial agonist effects.
Journal of neural transmission (Vienna, Austria : 1996) 1996;103(1-2):77-88.
1996: Michael Maes; Ingrid De Meester; Simon Scharpe; R Desnyder; R Ranjan; Herbert Y Meltzer
Alterations in plasma dipeptidyl peptidase IV enzyme activity in depression and schizophrenia: effects of antidepressants and antipsychotic drugs.
Acta psychiatrica Scandinavica 1996;93(1):1-8.
1996: Michael Maes; A Van Gastel; Herbert Y Meltzer; Paul Cosyns; P Blockx; R Desnyder
Acute administration of buspirone increases the escape of hypothalamic-pituitary-adrenal-axis hormones from suppression by dexamethasone in depression.
Psychoneuroendocrinology 1996;21(1):67-81.
1995: Michael Maes; E Vandoolaeghe; R Ranjan; Eugene Bosmans; R Bergmans; R Desnyder
Increased serum interleukin-1-receptor-antagonist concentrations in major depression.
Journal of affective disorders 1995;36(1-2):29-36.
1995: Michael Maes; Simon Scharpé; Robert Verkerk; P D'Hondt; D Peeters; Paul Cosyns; P Thompson; F De Meyer; Annick Wauters; Hugo Neels
Seasonal variation in plasma L-tryptophan availability in healthy volunteers. Relationships to violent suicide occurrence.
Archives of general psychiatry 1995;52(11):937-46.
1995: Michael Maes; F Goossens; Simon Scharpé; Joseph Calabrese; R Desnyder; Herbert Y Meltzer
Alterations in plasma prolyl endopeptidase activity in depression, mania, and schizophrenia: effects of antidepressants, mood stabilizers, and antipsychotic drugs.
Psychiatry research 1995;58(3):217-25.
1995: Herbert Y Meltzer; Michael Maes
Effects of ipsapirone on plasma cortisol and body temperature in major depression.
Biological psychiatry 1995;38(7):450-7.
1995: Herbert Y Meltzer; Michael Maes
Pindolol pretreatment blocks stimulation by meta-chlorophenylpiperazine of prolactin but not cortisol secretion in normal men.
Psychiatry research 1995;58(2):89-98.
1995: Herbert Y Meltzer; Michael Maes
Effect of pindolol pretreatment on MK-212-induced plasma cortisol and prolactin responses in normal men.
Biological psychiatry 1995;38(5):310-8.
1995: Michael Maes; Herbert Y Meltzer; Eugene Bosmans; R Bergmans; E Vandoolaeghe; R Ranjan; R Desnyder
Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression.
Journal of affective disorders 1995;34(4):301-9.
1995: Michael Maes; A Van Gastel; P Blockx; M Martin; Paul Cosyns; Simon Scharpé; R Desnyder
An augmented escape of androstenedione from suppression by dexamethasone in melancholia: relationships to intact ACTH and cortisol nonsuppression.
Journal of affective disorders 1995;34(4):291-300.
1995: Michael Maes; W Cooreman; J Delanghe; Simon Scharpé; Annick Wauters; Hugo Neels; P D'Hondt; D Peeters; Paul Cosyns; R Ranjan
Components of biological variation in plasma haptoglobin: relationships to plasma fibrinogen and immune variables, including interleukin-6 and its receptor.
Clinica chimica acta; international journal of clinical chemistry 1995;239(1):23-35.
1995: Michael Maes; Annick Wauters; Hugo Neels; Simon Scharpé; A Van Gastel; P D'Hondt; D Peeters; Paul Cosyns; R Desnyder
Total serum protein and serum protein fractions in depression: relationships to depressive symptoms and glucocorticoid activity.
Journal of affective disorders 1995;34(1):61-9.
1995: Michael Maes; Eugene Bosmans; Joseph Calabrese; R Smith; Herbert Y Meltzer
Interleukin-2 and interleukin-6 in schizophrenia and mania: effects of neuroleptics and mood stabilizers.
Journal of psychiatric research 1995;29(2):141-52.
1995: Michael Maes; Simon Scharpé; W Cooreman; Annick Wauters; Hugo Neels; Robert Verkerk; F De Meyer; P D'Hondt; D Peeters; Paul Cosyns
Components of biological, including seasonal, variation in hematological measurements and plasma fibrinogen concentrations in normal humans.
Experientia 1995;51(2):141-9.
1995: Michael Maes; Eugene Bosmans; Simon Scharpé; P D'Hondt; R Desnyder
Plasma soluble interleukin-2-receptor in depression: relationships to plasma neopterin and serum IL-2 concentrations and HPA-axis activity.
European psychiatry : the journal of the Association of European Psychiatrists 1995;10(8):397-403.
1995: Carlo A Altamura; Michael Maes; J Dai; Herbert Y Meltzer
Plasma concentrations of excitatory amino acids, serine, glycine, taurine and histidine in major depression.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1995;5 Suppl():71-5.
1995: A Carlo Altamura; G L Tacchini; Michael Maes
Haloperidol plasma 'threshold' levels for relapse prevention in schizophrenia: a study with haloperidol decanoate.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1995;5 Suppl():55-8.
1995: Michael Maes; Herbert Y Meltzer; P D'Hondt; Paul Cosyns; P Blockx
Effects of serotonin precursors on the negative feedback effects of glucocorticoids on hypothalamic-pituitary-adrenal axis function in depression.
Psychoneuroendocrinology 1995;20(2):149-67.
1995: Michael Maes; Herbert Y Meltzer; Peter F Buckley; Eugene Bosmans
Plasma-soluble interleukin-2 and transferrin receptor in schizophrenia and major depression.
European archives of psychiatry and clinical neuroscience 1995;244(6):325-9.
1995: Michael Maes
Evidence for an immune response in major depression: a review and hypothesis.
Progress in neuro-psychopharmacology & biological psychiatry 1995;19(1):11-38.
1995: Michael Maes; G De Backer; E Suy; B Minner
Increased plasma serine concentrations in depression.
Neuropsychobiology 1995;31(1):10-5.
1994: Michael Maes; Herbert Y Meltzer; Paul Cosyns; Joseph Calabrese; P D'Hondt; P Blockx
Adrenocorticotropic hormone, beta-endorphin and cortisol responses to oCRH in unipolar depressed patients pretreated with dexamethasone.
Progress in neuro-psychopharmacology & biological psychiatry 1994;18(8):1273-92.
1994: Michael Maes; F De Meyer; P Thompson; D Peeters; Paul Cosyns
Synchronized annual rhythms in violent suicide rate, ambient temperature and the light-dark span.
Acta psychiatrica Scandinavica 1994;90(5):391-6.
1994: Michael Maes; J Delanghe; Herbert Y Meltzer; Simon Scharpé; P D'Hondt; Paul Cosyns
Lower degree of esterification of serum cholesterol in depression: relevance for depression and suicide research.
Acta psychiatrica Scandinavica 1994;90(4):252-8.
1994: Michael Maes; Wim Stevens; Simon Scharpé; Eugene Bosmans; F De Meyer; P D'Hondt; D Peeters; P Thompson; Paul Cosyns; Luc S De Clerck
Seasonal variation in peripheral blood leukocyte subsets and in serum interleukin-6, and soluble interleukin-2 and -6 receptor concentrations in normal volunteers.
Experientia 1994;50(9):821-9.
1994: Michael Maes; Simon Scharpé; Ingrid De Meester; P Goossens; Annick Wauters; Hugo Neels; Robert Verkerk; F De Meyer; P D'Hondt; D Peeters
Components of biological variation in prolyl endopeptidase and dipeptidyl-peptidase IV activity in plasma of healthy subjects.
Clinical chemistry 1994;40(9):1686-91.
1994: P D'Hondt; Michael Maes; Josée E Leysen; W Gommeren; Simon Scharpé; Paul Cosyns
Binding of [3H]paroxetine to platelets of depressed patients: seasonal differences and effects of diagnostic classification.
Journal of affective disorders 1994;32(1):27-35.
1994: Michael Maes; Herbert Y Meltzer; Wim Stevens; Joseph Calabrese; Paul Cosyns
Natural killer cell activity in major depression: relation to circulating natural killer cells, cellular indices of the immune response, and depressive phenomenology.
Progress in neuro-psychopharmacology & biological psychiatry 1994;18(4):717-30.
1994: Michael Maes; P C D'Haese; Simon Scharpé; P D'Hondt; Paul Cosyns; M E De Broe
Hypozincemia in depression.
Journal of affective disorders 1994;31(2):135-40.
1994: P A Thompson; Michael Maes; Herbert Y Meltzer
Effect of the placebo control condition in neuroendocrine challenge studies.
Psychiatry research 1994;52(3):317-26.
1994: Michael Maes; Joseph Calabrese; Herbert Y Meltzer
The relevance of the in- versus outpatient status for studies on HPA-axis in depression: spontaneous hypercortisolism is a feature of major depressed inpatients and not of major depression per se.
Progress in neuro-psychopharmacology & biological psychiatry 1994;18(3):503-17.
1994: Michael Maes; Herbert Y Meltzer; Eugene Bosmans
Immune-inflammatory markers in schizophrenia: comparison to normal controls and effects of clozapine.
Acta psychiatrica Scandinavica 1994;89(5):346-51.
1994: Herbert Y Meltzer; Michael Maes
Effect of pindolol on the L-5-HTP-induced increase in plasma prolactin and cortisol concentrations in man.
Psychopharmacology 1994;114(4):635-43.
1994: Michael Maes; F Goossens; Simon Scharpé; Herbert Y Meltzer; P D'Hondt; Paul Cosyns
Lower serum prolyl endopeptidase enzyme activity in major depression: further evidence that peptidases play a role in the pathophysiology of depression.
Biological psychiatry 1994;35(8):545-52.
1994: Herbert Y Meltzer; Michael Maes
Effects of buspirone on plasma prolactin and cortisol levels in major depressed and normal subjects.
Biological psychiatry 1994;35(5):316-23.
1994: Michael Maes; Simon Scharpé; Paul Cosyns; Herbert Y Meltzer
Relationships between basal hypothalamic-pituitary-thyroid-axis activity and plasma haptoglobin levels in depression.
Journal of psychiatric research 1994;28(2):123-34.
1994: Michael Maes; Herbert Y Meltzer; Wim Stevens; Paul Cosyns; P Blockx
Multiple reciprocal relationships between in vivo cellular immunity and hypothalamic-pituitary-adrenal axis in depression.
Psychological medicine 1994;24(1):167-77.
1994: Michael Maes; P D'Hondt; P Blockx; Paul Cosyns
A further investigation of basal HPT axis function in unipolar depression: effects of diagnosis, hospitalization, and dexamethasone administration.
Psychiatry research 1994;51(2):185-201.
1994: Michael Maes; Joseph Calabrese; M Lee; Herbert Y Meltzer
Effects of age on spontaneous cortisolaemia of normal volunteers and depressed patients.
Psychoneuroendocrinology 1994;19(1):79-84.
1994: Michael Maes; J Delanghe; Simon Scharpé; Herbert Y Meltzer; Paul Cosyns; E Suy; Eugene Bosmans
Haptoglobin phenotypes and gene frequencies in unipolar major depression.
The American journal of psychiatry 1994;151(1):112-6.
1994: Michael Maes; Herbert Y Meltzer; P Blockx; Paul Cosyns; Joseph Calabrese
Ultrasensitive assay for measuring the intact (1-39) ACTH molecule: an asset in depression research.
Neuropsychobiology 1994;29(4):168-73.
1994: Michael Maes; J Lambrechts; E Suy; C Vandervorst; Eugene Bosmans
Absolute number and percentage of circulating natural killer, non-MHC-restricted T cytotoxic, and phagocytic cells in unipolar depression.
Neuropsychobiology 1994;29(4):157-63.
1994: Michael Maes; Herbert Y Meltzer; Paul Cosyns; chris schotte
Evidence for the existence of major depression with and without anxiety features.
Psychopathology 1994;27(1-2):1-13.
1994: Michael Maes; Herbert Y Meltzer; E Bosmans
Psychoimmune investigation in obsessive-compulsive disorder: assays of plasma transferrin, IL-2 and IL-6 receptor, and IL-1 beta and IL-6 concentrations.
Neuropsychobiology 1994;30(2-3):57-60.
1993: Michael Maes; Simon Scharpé; Herbert Y Meltzer; Paul Cosyns
Relationships between increased haptoglobin plasma levels and activation of cell-mediated immunity in depression.
Biological psychiatry 1993;34(10):690-701.
1993: Michael Maes
A review on the acute phase response in major depression.
Reviews in the neurosciences 1993;4(4):407-16.
1993: Michael Maes; Paul Cosyns; Herbert Y Meltzer; F De Meyer; D Peeters
Seasonality in violent suicide but not in nonviolent suicide or homicide.
The American journal of psychiatry 1993;150(9):1380-5.
1993: Michael Maes; Herbert Y Meltzer; E Suy; F De Meyer
Seasonality in severity of depression: relationships to suicide and homicide occurrence.
Acta psychiatrica Scandinavica 1993;88(3):156-61.
1993: Michael Maes; E Bosmans; Herbert Y Meltzer; Simon Scharpé; E Suy
Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression?
The American journal of psychiatry 1993;150(8):1189-93.
1993: Michael Maes; Herbert Y Meltzer; Simon Scharpé; W Cooreman; W Uyttenbroeck; E Suy; C Vandervorst; Joseph Calabrese; Jef Raus; Paul Cosyns
Psychomotor retardation, anorexia, weight loss, sleep disturbances, and loss of energy: psychopathological correlates of hyperhaptoglobinemia during major depression.
Psychiatry research 1993;47(3):229-41.
1993: chris schotte; Dirk A M De Doncker; Michael Maes; R Cluydts; P Cosyns
MMPI assessment of the DSM-III-R histrionic personality disorder.
Journal of personality assessment 1993;60(3):500-10.
1993: Michael Maes; F De Meyer; D Peeters; Herbert Y Meltzer; chris schotte; Simon Scharpe; Paul Cosyns
The periodicities in and biometeorological relationships with bed occupancy of an acute psychiatric ward in Antwerp, Belgium.
International journal of biometeorology 1993;37(2):78-82.
1993: Michael Maes; Herbert Y Meltzer; Paul Cosyns; Joseph Calabrese; P D'Hondt; P Blockx; C Vandervorst; Jef Raus
Pituitary and adrenal hormone responsiveness to Synacthen in melancholic subjects versus subjects with minor depression.
Biological psychiatry 1993;33(8-9):624-9.
1993: Michael Maes; Herbert Y Meltzer; E Suy; B Minner; Joseph Calabrese; Paul Cosyns
Sleep disorders and anxiety as symptom profiles of sympathoadrenal system hyperactivity in major depression.
Journal of affective disorders 1993;27(3):197-207.
1993: Michael Maes; Herbert Y Meltzer; J Jacobs; E Suy; Joseph Calabrese; B Minner; Jef Raus
Autoimmunity in depression: increased antiphospholipid autoantibodies.
Acta psychiatrica Scandinavica 1993;87(3):160-6.
1993: Michael Maes; W J Stevens; L S Declerck; Chris H Bridts; D Peeters; chris schotte; Paul Cosyns
Significantly increased expression of T-cell activation markers (interleukin-2 and HLA-DR) in depression: further evidence for an inflammatory process during that illness.
Progress in neuro-psychopharmacology & biological psychiatry 1993;17(2):241-55.
1993: Michael Maes; Herbert Y Meltzer; Paul Cosyns; E Suy; chris schotte
An evaluation of basal hypothalamic-pituitary-thyroid axis function in depression: results of a large-scaled and controlled study.
Psychoneuroendocrinology 1993;18(8):607-20.
1993: Herbert Y Meltzer; Michael Maes; M A Lee
The cimetidine-induced increase in prolactin secretion in schizophrenia: effect of clozapine.
Psychopharmacology 1993;112(1 Suppl):S95-104.
1992: Michael Maes; Wim Stevens; L DeClerck; Chris H Bridts; D Peeters; chris schotte; Paul Cosyns
Immune disorders in depression: higher T helper/T suppressor-cytotoxic cell ratio.
Acta psychiatrica Scandinavica 1992;86(6):423-31.
1992: Michael Maes; F De Meyer; D Peeters; Herbert Y Meltzer; Paul Cosyns; chris schotte
Seasonal variation and meteotropism in various self-rated psychological and physiological features of a normal couple.
International journal of biometeorology 1992;36(4):195-200.
1992: Michael Maes; Simon Scharpé; Herbert Y Meltzer; E Suy; Paul Cosyns; Joseph Calabrese
Lower angiotensin I converting enzyme activity in melancholic subjects: a pilot study.
Biological psychiatry 1992;32(7):621-4.
1992: Michael Maes; L Maes; chris schotte; Paul Cosyns
A clinical and biological validation of the DSM-III melancholia diagnosis in men: results of pattern recognition methods.
Journal of psychiatric research 1992;26(3):183-96.
1992: Michael Maes; Simon Scharpe; E Bosmans; M Vandewoude; E Suy; W Uyttenbroeck; W Cooreman; C Vandervorst; Jef Raus
Disturbances in acute phase plasma proteins during melancholia: additional evidence for the presence of an inflammatory process during that illness.
Progress in neuro-psychopharmacology & biological psychiatry 1992;16(4):501-15.
1992: Michael Maes; Wim Stevens; L DeClerck; D Peeters; Chris H Bridts; chris schotte; Herbert Y Meltzer; Simon Scharpé; Paul Cosyns
Neutrophil chemotaxis, phagocytosis, and superoxide release in depressive illness.
Biological psychiatry 1992;31(12):1220-4.
1992: Michael Maes; chris schotte; M Vandewoude; M Martin; P Blockx
TSH responses to TRH as a function of basal serum TSH: relevance for unipolar depression in females--a multivariate study.
Pharmacopsychiatry 1992;25(3):136-44.
1992: Michael Maes; M Claes; M Vandewoude; chris schotte; M Martin; P Blockx; Paul Cosyns
Adrenocorticotropin hormone, beta-endorphin and cortisol responses to oCRF in melancholic patients.
Psychological medicine 1992;22(2):317-29.
1992: Michael Maes; M Van der Planken; Wim J Stevens; D Peeters; L S DeClerck; Chris H Bridts; chris schotte; Paul Cosyns
Leukocytosis, monocytosis and neutrophilia: hallmarks of severe depression.
Journal of psychiatric research 1992;26(2):125-34.
1992: Michael Maes; Simon Scharpé; L Van Grootel; W Uyttenbroeck; W Cooreman; Paul Cosyns; E Suy
Higher alpha 1-antitrypsin, haptoglobin, ceruloplasmin and lower retinol binding protein plasma levels during depression: further evidence for the existence of an inflammatory response during that illness.
Journal of affective disorders 1992;24(3):183-92.
1992: Michael Maes; W J Stevens; L S DeClerck; Chris H Bridts; D Peeters; chris schotte; Paul Cosyns
A significantly increased number and percentage of B cells in depressed subjects: results of flow cytometric measurements.
Journal of affective disorders 1992;24(3):127-34.
1992: Michael Maes; J Lambrechts; E Bosmans; J Jacobs; E Suy; C Vandervorst; C de Jonckheere; B Minner; Jef Raus
Evidence for a systemic immune activation during depression: results of leukocyte enumeration by flow cytometry in conjunction with monoclonal antibody staining.
Psychological medicine 1992;22(1):45-53.
1992: Michael Maes; M Claes; chris schotte; L Delbeke; Y Jacquemyn; Robert Verkerk; Ingrid De Meester; Simon Scharpé
Disturbances in dexamethasone suppression test and lower availability of L-tryptophan and tyrosine in early puerperium and in women under contraceptive therapy.
Journal of psychosomatic research 1992;36(2):191-7.
1992: Michael Maes; Wim Stevens; D Peeters; L DeClerck; Simon Scharpe; Chris H Bridts; chris schotte; Paul Cosyns
A study on the blunted natural killer cell activity in severely depressed patients.
Life sciences 1992;50(7):505-13.
1991: chris schotte; Dirk A M De Doncker; Michael Maes; R Cluydts; P Cosyns
Low MMPI diagnostic performance for the DSM-III--R obsessive-compulsive personality disorder.
Psychological reports 1991;69(3 Pt 1):795-800.
1991: Michael Maes; E Bosmans; E Suy; C Vandervorst; C DeJonckheere; Jef Raus
Depression-related disturbances in mitogen-induced lymphocyte responses and interleukin-1 beta and soluble interleukin-2 receptor production.
Acta psychiatrica Scandinavica 1991;84(4):379-86.
1991: Michael Maes; Ingrid De Meester; G Vanhoof; Simon Scharpé; E Bosmans; C Vandervorst; Robert Verkerk; B Minner; E Suy; Jef Raus
Decreased serum dipeptidyl peptidase IV activity in major depression.
Biological psychiatry 1991;30(6):577-86.
1991: Michael Maes; M Vandewoude; Simon Scharpé; L De Clercq; Wim Stevens; L Lepoutre; chris schotte
Anthropometric and biochemical assessment of the nutritional state in depression: evidence for lower visceral protein plasma levels in depression.
Journal of affective disorders 1991;23(1):25-33.
1991: chris schotte; Michael Maes; R Cluydts; Dirk A M De Doncker; M Claes; P Cosyns
MMPI characteristics of the DSM-III-R avoidant personality disorder.
Psychological reports 1991;69(1):75-81.
1991: Michael Maes; C DeJonckheere; C Vandervorst; chris schotte; Paul Cosyns; Jef Raus; E Suy
Abnormal pituitary function during melancholia: reduced alpha-melanocyte-stimulating hormone secretion and increased intact ACTH non-suppression.
Journal of affective disorders 1991;22(3):149-57.
1991: Michael Maes; C Vandervorst; E Suy; B Minner; Jef Raus
A multivariate study of simultaneous escape from suppression by dexamethasone of urinary free cortisol, plasma cortisol, adrenocorticotropic hormone and beta-endorphin in melancholic patients.
Acta psychiatrica Scandinavica 1991;83(6):480-91.
1991: Michael Maes; E Bosmans; E Suy; B Minner; Jef Raus
A further exploration of the relationships between immune parameters and the HPA-axis activity in depressed patients.
Psychological medicine 1991;21(2):313-20.
1991: Michael Maes; P D'Hondt; M Martin; M Claes; chris schotte; M Vandewoude; P Blockx
L-5-hydroxytryptophan stimulated cortisol escape from dexamethasone suppression in melancholic patients.
Acta psychiatrica Scandinavica 1991;83(4):302-6.
1991: Michael Maes; E Bosmans; E Suy; C Vandervorst; C Dejonckheere; Jef Raus
Antiphospholipid, antinuclear, Epstein-Barr and cytomegalovirus antibodies, and soluble interleukin-2 receptors in depressive patients.
Journal of affective disorders 1991;21(2):133-40.
1991: Michael Maes; chris schotte; D Peeters; P D'Hondt; M Martin; P Blockx; B Minner; E Suy; Paul Cosyns
Serum postdexamethasone prolactin measures in depressive patients and control subjects.
Journal of psychiatric research 1991;25(3):109-16.
1991: Michael Maes; B Minner; E Suy; C Vandervorst; Jef Raus
Coexisting dysregulations of both the sympathoadrenal system and hypothalamic-pituitary-adrenal-axis in melancholia.
Journal of neural transmission. General section 1991;85(3):195-210.
1991: B Van den Bossche; Michael Maes; C Brussaard; chris schotte; Paul Cosyns; J De Moor; A De Schepper
Computed tomography of the brain in unipolar depression.
Journal of affective disorders 1991;21(1):67-74.
1991: Michael Maes; B Minner; E Suy; P D'Hondt; M P Jacobs; Jef Raus
Cortisol escape from suppression by dexamethasone during depression is strongly predicted by basal cortisol hypersecretion and increasing age combined.
Psychoneuroendocrinology 1991;16(4):295-310.
1991: Michael Maes; P D'Hondt; E Suy; B Minner; C Vandervorst; Jef Raus
HPA-axis hormones and prolactin responses to dextro-fenfluramine in depressed patients and healthy controls.
Progress in neuro-psychopharmacology & biological psychiatry 1991;15(6):781-90.
1991: Michael Maes; chris schotte; P D'Hondt; M Claes; M Vandewoude; Simon Scharpe; Paul Cosyns
Biological heterogeneity of melancholia: results of pattern recognition methods.
Journal of psychiatric research 1991;25(3):95-108.
1990: Michael Maes; M Vandewoude; chris schotte; L Maes; M Martin; P Blockx
A revised interpretation of postdexamethasone ACTH and cortisol findings in unipolar depressed females.
Psychiatry research 1990;34(2):107-26.
1990: Michael Maes; chris schotte; L Maes; Paul Cosyns
Clinical subtypes of unipolar depression: Part II. Quantitative and qualitative clinical differences between the vital and nonvital depression groups.
Psychiatry research 1990;34(1):43-57.
1990: Michael Maes; Paul Cosyns; L Maes; P D'Hondt; chris schotte
Clinical subtypes of unipolar depression: Part I. A validation of the vital and nonvital clusters.
Psychiatry research 1990;34(1):29-41.
1990: Michael Maes; L Maes; chris schotte; M Vandewoude; M Martin; P D'Hondt; P Blockx; Simon Scharpé; Paul Cosyns
Clinical subtypes of unipolar depression: Part III. Quantitative differences in various biological markers between the cluster-analytically generated nonvital and vital depression classes.
Psychiatry research 1990;34(1):59-75.
1990: Michael Maes; M Vandewoude; chris schotte; M Martin; P Blockx
Suppressive effects of dexamethasone on hypothalamic-pituitary-thyroid axis function in depressed patients.
Journal of affective disorders 1990;20(1):55-61.
1990: Michael Maes; M P Jacobs; E Suy; B Minner; Jef Raus
Prediction of the DST results in depressives by means of urinary-free cortisol excretion, dexamethasone levels, and age.
Biological psychiatry 1990;28(4):349-57.
1990: Michael Maes; M Vandewoude; chris schotte; M Martin; P Blockx
Positive relationship between the catecholaminergic turnover and the DST results in depression.
Psychological medicine 1990;20(3):493-9.
1990: Michael Maes; M P Jacobs; E Suy; M Vandewoude; B Minner; Jef Raus
Effects of dexamethasone on the availability of L-tryptophan and on the insulin and FFA concentrations in unipolar depressed patients.
Biological psychiatry 1990;27(8):854-62.
1990: Michael Maes; M Vandewoude; chris schotte; L Maes; M Martin; Simon Scharpe; P Blockx
The relationships between the cortisol responses to dexamethasone and to L-5-HTP, and the availability of L-tryptophan in depressed females.
Biological psychiatry 1990;27(6):601-8.
1990: Michael Maes; M P Jacobs; E Suy; C Leclercq; F Christiaens; Jef Raus
An augmented escape of beta-endorphins to suppression by dexamethasone in severely depressed patients.
Journal of affective disorders 1990;18(3):149-56.
1990: Michael Maes; chris schotte; Simon Scharpé; M Martin; P Blockx
The effects of glucocorticoids on the availability of L-tryptophan and tyrosine in the plasma of depressed patients.
Journal of affective disorders 1990;18(2):121-7.
1990: Michael Maes; M P Jacobs; E Suy; B Minner; C Leclercq; F Christiaens; Jef Raus
Suppressant effects of dexamethasone on the availability of plasma L-tryptophan and tyrosine in healthy controls and in depressed patients.
Acta psychiatrica Scandinavica 1990;81(1):19-23.
1990: Michael Maes; M Vandewoude; chris schotte; M Martin; P D'Hondt; Simon Scharpe; P Blockx
The decreased availability of L-tryptophan in depressed females: clinical and biological correlates.
Progress in neuro-psychopharmacology & biological psychiatry 1990;14(6):903-19.
1990: Michael Maes; E Bosmans; E Suy; C Vandervorst; C De Jonckheere; Jef Raus
Immune disturbances during major depression: upregulated expression of interleukin-2 receptors.
Neuropsychobiology 1990;24(3):115-20.
1990: Michael Maes; L Maes; E Suy
Symptom profiles of biological markers in depression: a multivariate study.
Psychoneuroendocrinology 1990;15(1):29-37.
1989: Michael Maes; E Bosmans; E Suy; B Minner; Jef Raus
Impaired lymphocyte stimulation by mitogens in severely depressed patients. A complex interface with HPA-axis hyperfunction, noradrenergic activity and the ageing process.
The British journal of psychiatry : the journal of mental science 1989;155():793-8.
1989: Michael Maes; M Vandewoude; chris schotte; L Maes; M Martin; P Blockx
Sex-linked differences in cortisol, ACTH and prolactin responses to 5-hydroxy-tryptophan in healthy controls and minor and major depressed patients.
Acta psychiatrica Scandinavica 1989;80(6):584-90.
1989: Michael Maes; R Vandevelde; E Suy
Influences on cortisol and noradrenergic turnover of healthy controls and depressed patients during L-tryptophan loading.
Journal of affective disorders 1989;17(2):173-82.
1989: Michael Maes; E Bosmans; E Suy; B Minner; Jef Raus
Immune cell parameters in severely depressed patients: negative findings.
Journal of affective disorders 1989;17(2):121-8.
1989: Michael Maes; M Vandewoude; chris schotte; M Martin; P Blockx; Simon Scharpe; Paul Cosyns
Hypothalamic-pituitary-adrenal and -thyroid axis dysfunctions and decrements in the availability of L-tryptophan as biological markers of suicidal ideation in major depressed females.
Acta psychiatrica Scandinavica 1989;80(1):13-7.
1989: Michael Maes; B Minner; E Suy
The influences of dexamethasone levels on the predictive value of the DST for unipolar major depression and the relationships between post-dexamethasone cortisol and ACTH levels.
Journal of affective disorders 1989;17(1):39-46.
1989: Michael Maes; M Vandewoude; L Maes; chris schotte; Paul Cosyns
A revised interpretation of the TRH test results in female depressed patients. Part II: Prolactin responses. Relationships with sex hormones, corticosteroid state, age, monoamines and amino acid levels.
Journal of affective disorders 1989;16(2-3):215-21.
1989: Michael Maes; M Vandewoude; L Maes; chris schotte; Paul Cosyns
A revised interpretation of the TRH test results in female depressed patients. Part I: TSH responses. Effects of severity of illness, thyroid hormones, monoamines, age, sex hormonal, corticosteroid and nutritional state.
Journal of affective disorders 1989;16(2-3):203-13.
1989: Michael Maes; M De Ruyter; E Suy
Use of the dexamethasone suppression test in an inpatient setting: a replication and new findings.
Psychoneuroendocrinology 1989;14(3):231-9.
1989: Michael Maes; M Vandewoude; chris schotte; Paul Cosyns
Results of the 8 a.m. dexamethasone suppression test constitute a suitable tool for confirming the diagnosis of melancholia. A test unaffected by the variations in the bioavailability of dexamethasone.
Neuropsychobiology 1989;22(1):26-32.
1989: Michael Maes; M P Jacobs; E Suy; B Minner; Jef Raus
Cortisol, ACTH, prolactin and beta-endorphin responses to fenfluramine administration in major-depressed patients.
Neuropsychobiology 1989;21(4):192-6.
1989: Paul Cosyns; Michael Maes; M Vandewoude; W J Stevens; Luc S De Clerck; chris schotte
Impaired mitogen-induced lymphocyte responses and the hypothalamic-pituitary-adrenal axis in depressive disorders.
Journal of affective disorders 1989;16(1):41-8.
1988: Michael Maes; M De Ruyter; R Claes; E Suy
Sex-related differences in the relationships between self-rated depression and biological markers.
Journal of affective disorders 1988;15(2):119-25.
1988: Michael Maes; M De Ruyter; R Claes; E Suy
Self rated depression in relation to DSM-III classification: a statistical isolinear multiple components analysis.
Acta psychiatrica Scandinavica 1988;77(1):27-31.
1987: Michael Maes; M De Ruyter; P Hobin; E Suy
Relationship between the dexamethasone suppression test and the L-tryptophan/competing amino acids ratio in depression.
Psychiatry research 1987;21(4):323-35.
1987: Michael Maes; M De Ruyter; R Claes; G Bosma; E Suy
The cortisol responses to 5-hydroxytryptophan, orally, in depressive inpatients.
Journal of affective disorders 1987;13(1):23-30.
1987: Michael Maes; M De Ruyter; E Suy
Prediction of subtype and severity of depression by means of dexamethasone suppression test, L-tryptophan: competing amino acid ratio, and MHPG flow.
Biological psychiatry 1987;22(2):177-88.
1987: Michael Maes; M de Ruyter; E Suy
Cortisol response to dexamethasone and noradrenergic function in depression.
Acta psychiatrica Scandinavica 1987;75(2):171-5.
1987: Michael Maes; M De Ruyter; E Suy
The cortisol suppression index and the dexamethasone suppression test in major depression.
Acta psychiatrica Belgica 1987;87():633-9.
1986: Michael Maes; M De Ruyter; P Hobin; E Suy
Repeated dexamethasone suppression test in depressed patients.
Journal of affective disorders 1986;11(2):165-72.
1986: Michael Maes; M De Ruyter; P Hobin; E Suy
The diagnostic performance of the L-tryptophan/competing amino acids ratio in major depression.
Acta psychiatrica Belgica 1986;86(3):257-65.
1986: Michael Maes; M De Ruyter; E Suy
The importance of creatinine flow, age and 24 h urinary output in the interpretation of the MHPG flow.
Journal of affective disorders 1986;10(3):221-5.
1986: Michael Maes; M De Ruyter; P Hobin; E Suy
The dexamethasone suppression test, the Hamilton Depression Rating Scale and the DSM-III depression categories.
Journal of affective disorders 1986;10(3):207-14.
1986: Michael Maes; M De Ruyter; E Suy
Xanthurenic acid flow in 24-hour urine following L-tryptophan loading in depressive patients.
Acta psychiatrica Belgica 1986;86(2):120-30.