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RA Mageed

Research Profile

Chemicals & Drugs

Disorders

Rheumatoid Arthritis

Genes & Molecular Sequences

Living Beings

Anatomy

Concepts & Ideas

Molecular Sequence Data

Physiology

B Lymphocyte Light Chain Gene Rearrangement

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Publications

TOP 3
Charles G Mackworth-Young; IJ Harmer; RA Mageed
The role of antigen in the selection of the human V3-23 immunoglobulin heavy chain variable region gene.
J Vencovský; E Zd'árský; SP Moyes; Al Hajeer; S Ruzicková; Z Cimburek; WE Ollier; Ravinder N Maini; RA Mageed
Polymorphism in the immunoglobulin VH gene V1-69 affects susceptibility to rheumatoid arthritis in subjects lacking the HLA-DRB1 shared epitope.
J Vencovský; K Jarosová; S Růzicková; Dana Nemcová; J Niederlová; S Ozen; M Alikasifoglu; A Bakkaloglu; WE Ollier; RA Mageed
Higher frequency of allele 2 of the interleukin-1 receptor antagonist gene in patients with juvenile idiopathic arthritis.

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All Publications

2003: Charles G Mackworth-Young; IJ Harmer; RA Mageed
The role of antigen in the selection of the human V3-23 immunoglobulin heavy chain variable region gene.
Clinical and experimental immunology 2003;134(3):420-5.
2002: J Vencovský; E Zd'árský; SP Moyes; Al Hajeer; S Ruzicková; Z Cimburek; WE Ollier; Ravinder N Maini; RA Mageed
Polymorphism in the immunoglobulin VH gene V1-69 affects susceptibility to rheumatoid arthritis in subjects lacking the HLA-DRB1 shared epitope.
Rheumatology (Oxford, England) 2002;41(4):401-10.
2001: J Vencovský; K Jarosová; S Růzicková; Dana Nemcová; J Niederlová; S Ozen; M Alikasifoglu; A Bakkaloglu; WE Ollier; RA Mageed
Higher frequency of allele 2 of the interleukin-1 receptor antagonist gene in patients with juvenile idiopathic arthritis.
Arthritis and rheumatism 2001;44(10):2387-91.
2001: A N Mason; RA Mageed; Charles G Mackworth-Young
The effects of a human IgM monoclonal anticardiolipin antibody on pregnancy in a transgenic mouse model.
Lupus 2001;10(4):289-94.
2001: RA Mageed; IJ Harmer; S L Wynn; SP Moyes; B B Maziak; M Brüggemann; Charles G Mackworth-Young
Rearrangement of the human heavy chain variable region gene V3-23 in transgenic mice generates antibodies reactive with a range of antigens on the basis of VHCDR3 and residues intrinsic to the heavy chain variable region.
Clinical and experimental immunology 2001;123(1):1-8.
2000: S Suleyman; Keith M Thompson; RA Mageed; Jacob B Natvig
Molecular analysis of human immunoglobulin heavy chain variable region associated determinants recognized by anti-VH3 antibodies 7B4, B6 and D12.
Scandinavian journal of immunology 2000;52(4):341-7.
2000: Yuti Chernajovsky; Hanna Dreja; Gordon M Daly; Alexander E Annenkov; David Gould; Gill Adams; J. Ludovic Croxford; David Baker; Osvaldo L Podhajcer; RA Mageed
Immuno- and genetic therapy in autoimmune diseases.
Genes and immunity 2000;1(5):295-307.
1999: david williams; SP Moyes; RA Mageed
Rheumatoid factor isotype switch and somatic mutation variants within rheumatoid arthritis synovium.
Immunology 1999;98(1):123-36.
1999: A N Mason; IJ Harmer; RA Mageed; Charles G Mackworth-Young
The BH1 idiotype defines a population of anticardiolipin antibodies closely associated with the antiphospholipid syndrome.
Lupus 1999;8(3):234-9.
1998: Alexander E Annenkov; SP Moyes; Z Eshhar; RA Mageed; Yuti Chernajovsky
Loss of original antigenic specificity in T cell hybridomas transduced with a chimeric receptor containing single-chain Fv of an anti-collagen antibody and Fc epsilonRI-signaling gamma subunit.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6604-13.
1998: RA Mageed; Gill Adams; D Woodrow; Osvaldo L Podhajcer; Yuti Chernajovsky
Prevention of collagen-induced arthritis by gene delivery of soluble p75 tumour necrosis factor receptor.
Gene therapy 1998;5(12):1584-92.
1998: SP Moyes; Ravinder N Maini; RA Mageed
Differential use of immunoglobulin light chain genes and B lymphocyte expansion at sites of disease in rheumatoid arthritis (RA) compared with circulating B lymphocytes.
Clinical and experimental immunology 1998;113(2):276-88.
1998: Yuti Chernajovsky; Alexander E Annenkov; C Herman; Kostas Triantaphyllopoulos; David Gould; Hanna Dreja; SP Moyes; J. Ludovic Croxford; RA Mageed; Osvaldo L Podhajcer; David Baker
Gene therapy for rheumatoid arthritis. Theoretical considerations.
Drugs & aging 1998;12(1):29-41.
1997: J Vencovský; Ravinder N Maini; WE Ollier; RA Mageed
Immunoglobulin variable region (IgV) gene expression in rheumatoid factors from monozygotic twins with rheumatoid arthritis.
Annals of the New York Academy of Sciences 1997;815():324-6.
1997: RA Mageed; SP Moyes; J Vencovský; Ravinder N Maini
Somatic mutation and CDR3 length of immunoglobulin lambda variable region genes in the synovium of patients with rheumatoid arthritis.
Annals of the New York Academy of Sciences 1997;815():319-23.
1997: RA Mageed; M Børretzen; SP Moyes; Keith M Thompson; Jacob B Natvig
Rheumatoid factor autoantibodies in health and disease.
Annals of the New York Academy of Sciences 1997;815():296-311.
1996: SP Moyes; C M Brown; B B Scott; Ravinder N Maini; RA Mageed
Analysis of V kappa genes in rheumatoid arthritis (RA) synovial B lymphocytes provides evidence for both polyclonal activation and antigen-driven selection.
Clinical and experimental immunology 1996;105(1):89-98.
1996: I J Harmer; RA Mageed; A Kaminski; P Charles; M Brüggemann; C G Mackworth-Young
Chimaeric monoclonal antibodies encoded by the human VH26 gene from naïve transgenic mice display a wide range of antigen-binding specificities.
Immunology 1996;88(2):174-82.
1995: A J MacGregor; W E R Ollier; J Venkovsky; RA Mageed; D Carthy; Alan J Silman
Rheumatoid factor isotypes in monozygotic and dizygotic twins discordant for rheumatoid arthritis.
The Journal of rheumatology 1995;22(12):2203-7.
1995: J Vencovsky; RA Mageed; W E R Ollier; Ravinder N Maini
Monozygotic rheumatoid arthritis twin pairs express similar levels of conserved immunoglobulin V gene in polyclonal rheumatoid factors irrespective of disease status.
Scandinavian journal of immunology 1995;42(1):147-57.
1995: C M Brown; K J Fitzgerald; SP Moyes; RA Mageed; david williams; Ravinder N Maini
Sequence analysis of immunoglobulin heavy-chain variable region genes from the synovium of a rheumatoid arthritis patient shows little evidence of mutation but diverse CDR3.
Immunology 1995;84(3):367-74.
1995: A J MacGregor; S Bamber; D Carthy; J Vencovsky; RA Mageed; W E R Ollier; Alan J Silman
Heterogeneity of disease phenotype in monozygotic twins concordant for rheumatoid arthritis.
British journal of rheumatology 1995;34(3):215-20.
1994: B B Scott; S Sadigh; E M Andrew; Ravinder N Maini; RA Mageed
Affinity maturation and isotype switch in clonally related anti-erythrocyte autoantibodies.
Scandinavian journal of immunology 1994;40(1):16-21.
1994: S Sadigh; B B Scott; RA Mageed; A Malcolm; E M Andrew; Ravinder N Maini
Identification of hybridomas derived from mouse CD5+ B lymphocytes by fluorescent staining for cytoplasmic CD5 expression.
Immunology 1994;81(4):558-63.
1994: RA Mageed; J Vencovsky; Ravinder N Maini
Rheumatoid factors and germline genes in rheumatoid arthritis: evidence of an intrinsic B-lymphocyte defect?
British journal of rheumatology 1994;33(2):105-7.
1993: B B Scott; S Sadigh; M Stow; RA Mageed; E M Andrew; Ravinder N Maini
Anti-mouse red blood cell monoclonal antibodies use functionally rearranged genes from the VH J558 family and are derived from the CD5- B-lymphocyte subpopulation.
Immunology 1993;79(4):568-73.
1993: B B Scott; S Sadigh; M Stow; RA Mageed; E M Andrew; Ravinder N Maini
Molecular mechanisms resulting in pathogenic anti-mouse erythrocyte antibodies in New Zealand black mice.
Clinical and experimental immunology 1993;93(1):26-33.