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Thomas Magin

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TOP 3
Alexander Zimek; Sören Thiering; Klaus Weber; Thomas M Magin
Genes encoding cytoplasmic intermediate filament proteins of vertebrates revisited: identification of a cytoplasmic intermediate filament protein in the sea anemone Nematostella.
Stefanie Löffek; Leena Bruckner-Tuderman; Thomas M Magin
Involvement of the ubiquitin-proteasome system in the stabilization of cell-cell contacts in human keratinocytes.
Reinhard Windoffer; Thomas M Magin; Michael Beil; Rudolf Leube
Cytoskeleton in motion: the dynamics of keratin intermediate filaments in epithelia.

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All Publications

2012: Alexander Zimek; Sören Thiering; Klaus Weber; Thomas M Magin
Genes encoding cytoplasmic intermediate filament proteins of vertebrates revisited: identification of a cytoplasmic intermediate filament protein in the sea anemone Nematostella.
European journal of cell biology 2012;91(10):809-17.
2012: Stefanie Löffek; Leena Bruckner-Tuderman; Thomas M Magin
Involvement of the ubiquitin-proteasome system in the stabilization of cell-cell contacts in human keratinocytes.
Experimental dermatology 2012;21(10):791-3.
2011: Reinhard Windoffer; Thomas M Magin; Michael Beil; Rudolf Leube
Cytoskeleton in motion: the dynamics of keratin intermediate filaments in epithelia.
The Journal of cell biology 2011;194(5):669-78.
2010: Stefanie Löffek; Stefan Wöll; Jörg Höhfeld; Rudolf E Leube; Cristina Has; Leena Bruckner-Tuderman; Thomas M Magin
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.
Human mutation 2010;31(4):466-76.
2009: Preethi Vijayaraj; Cornelia Kröger; Ursula Reuter; Reinhard Windoffer; Rudolf E Leube; Thomas M Magin
Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor.
The Journal of cell biology 2009;187(2):175-84.
2009: Wera Roth; Ursula Reuter; Claudia Wohlenberg; Leena Bruckner-Tuderman; Thomas M Magin
Cytokines as genetic modifiers in K5-/- mice and in human epidermolysis bullosa simplex.
Human mutation 2009;30(5):832-41.
2008: Roland Bornheim; Martin Müller; Uschi Reuter; Harald Herrmann; Heinrich Büssow; Thomas M Magin
A dominant vimentin mutant upregulates Hsp70 and the activity of the ubiquitin-proteasome system, and causes posterior cataracts in transgenic mice.
Journal of cell science 2008;121(Pt 22):3737-46.
2007: Hong Lu; Jian Chen; Laura Planko; Paola Zigrino; Ludger Klein-Hitpass; Thomas M Magin
Induction of inflammatory cytokines by a keratin mutation and their repression by a small molecule in a mouse model for EBS.
The Journal of investigative dermatology 2007;127(12):2781-9.
2007: Laura Planko; Karsten Böhse; Jörg Höhfeld; Regina C Betz; Sandra Hanneken; Sibylle Eigelshoven; Roland Kruse; Markus M Nöthen; Thomas M Magin
Identification of a keratin-associated protein with a putative role in vesicle transport.
European journal of cell biology 2007;86(11-12):827-39.
2007: Michael Hesse; Christine Grund; Harald Herrmann; Dominique Bröhl; Thomas Franz; Bishr Omary; Thomas M Magin
A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice.
Experimental cell research 2007;313(14):3127-40.
2007: Thomas M Magin; Preethi Vijayaraj; Rudolf E Leube
Structural and regulatory functions of keratins.
Experimental cell research 2007;313(10):2021-32.
2007: Preethi Vijayaraj; Goran Söhl; Thomas M Magin
Keratin transgenic and knockout mice: functional analysis and validation of disease-causing mutations.
Methods in molecular biology (Clifton, N.J.) 2007;360():203-51.
2006: Hong Lu; Alexander Zimek; Jian Chen; Michael Hesse; Heinrich Büssow; Klaus Weber; Thomas M Magin
Keratin 5 knockout mice reveal plasticity of keratin expression in the corneal epithelium.
European journal of cell biology 2006;85(8):803-11.
2006: Jürgen Schweizer; Paul E Bowden; Pierre A Coulombe; Lutz Langbein; E Birgitte Lane; Thomas M Magin; Lois Maltais; Bishr Omary; David A D Parry; Michael A Rogers; Mathew W Wright
New consensus nomenclature for mammalian keratins.
The Journal of cell biology 2006;174(2):169-74.
2006: Pavel Strnad; Tim Christian Lienau; Guo-Zhong Tao; Nam-On Ku; Thomas M Magin; Bishr Omary
Denaturing temperature selection may underestimate keratin mutation detection by DHPLC.
Human mutation 2006;27(5):444-52.
2006: Regina C Betz; Laura Planko; Sibylle Eigelshoven; Sandra Hanneken; Sandra M Pasternack; Heinrich Bussow; Kris Van Den Bogaert; Joerg Wenzel; Markus Braun-Falco; Arno Rutten; Michael A Rogers; Thomas Ruzicka; Markus M Nöthen; Thomas M Magin; Roland Kruse
Loss-of-function mutations in the keratin 5 gene lead to Dowling-Degos disease.
American journal of human genetics 2006;78(3):510-9.
2006: Ruth Schietke; Dominique Bröhl; Tatjana Wedig; Norbert Mücke; Harald Herrmann; Thomas M Magin
Mutations in vimentin disrupt the cytoskeleton in fibroblasts and delay execution of apoptosis.
European journal of cell biology 2006;85(1):1-10.
2005: Hong Lu; Michael Hesse; Bettina Peters; Thomas M Magin
Type II keratins precede type I keratins during early embryonic development.
European journal of cell biology 2005;84(8):709-18.
2005: Mark Kibschull; Thomas M Magin; Otto Traub; Elke Winterhager
Cx31 and Cx43 double-deficient mice reveal independent functions in murine placental and skin development.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;233(3):853-63.
2005: Michael Hesse; Erica D Watson; Tanja Schwaluk; Thomas M Magin
Rescue of keratin 18/19 doubly deficient mice using aggregation with tetraploid embryos.
European journal of cell biology 2005;84(2-3):355-61.
2004: Julia Reichelt; Bernadette Breiden; Konrad Sandhoff; Thomas M Magin
Loss of keratin 10 is accompanied by increased sebocyte proliferation and differentiation.
European journal of cell biology 2004;83(11-12):747-59.
2004: Thomas M Magin; Julia Reichelt; Mechthild Hatzfeld
Emerging functions: diseases and animal models reshape our view of the cytoskeleton.
Experimental cell research 2004;301(1):91-102.
2004: Julia Reichelt; Gerhard Furstenberger; Thomas M Magin
Loss of keratin 10 leads to mitogen-activated protein kinase (MAPK) activation, increased keratinocyte turnover, and decreased tumor formation in mice.
The Journal of investigative dermatology 2004;123(5):973-81.
2004: Thomas M Magin
Animal models of human skin disease.
Experimental dermatology 2004;13(10):659-60.
2004: Nicola Susann Werner; Reinhard Windoffer; Pavel Strnad; Christine Grund; Rudolf E Leube; Thomas M Magin
Epidermolysis bullosa simplex-type mutations alter the dynamics of the keratin cytoskeleton and reveal a contribution of actin to the transport of keratin subunits.
Molecular biology of the cell 2004;15(3):990-1002.
2004: Michael Hesse; Alexander Zimek; Klaus Weber; Thomas M Magin
Comprehensive analysis of keratin gene clusters in humans and rodents.
European journal of cell biology 2004;83(1):19-26.
2004: Thomas M Magin; Michael Hesse; Roland Meier-Bornheim; Julia Reichelt
Developing mouse models to study intermediate filament function.
Methods in cell biology 2004;78():65-94.
2003: Harald Herrmann; Michael Hesse; Michaela Reichenzeller; Ueli Aebi; Thomas M Magin
Functional complexity of intermediate filament cytoskeletons: from structure to assembly to gene ablation.
International review of cytology 2003;223():83-175.
2003: Jutta Kirfel; Thomas M Magin; Julia Reichelt
Keratins: a structural scaffold with emerging functions.
Cellular and molecular life sciences : CMLS 2003;60(1):56-71.
2002: Rebecca M Porter; Colin A B Jahoda; Declan P Lunny; Gayle Henderson; Jane Ross; W H Irwin McLean; Neil Whittock; Neil J Wilson; Julia Reichelt; Thomas M Magin; E Birgitte Lane
Defolliculated (dfl): a dominant mouse mutation leading to poor sebaceous gland differentiation and total elimination of pelage follicles.
The Journal of investigative dermatology 2002;119(1):32-7.
2002: Julia Reichelt; Thomas M Magin
Hyperproliferation, induction of c-Myc and 14-3-3sigma, but no cell fragility in keratin-10-null mice.
Journal of cell science 2002;115(Pt 13):2639-50.
2002: Jutta Kirfel; Bettina Peters; Christine Grund; Kurt Reifenberg; Thomas M Magin
Ectopic expression of desmin in the epidermis of transgenic mice permits development of a normal epidermis.
Differentiation; research in biological diversity 2002;70(1):56-68.
2001: Michael Hesse; Thomas M Magin; K Weber
Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18.
Journal of cell science 2001;114(Pt 14):2569-75.
2001: Bettina Peters; Jutta Kirfel; Heinrich Büssow; Miguel Vidal; Thomas M Magin
Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex.
Molecular biology of the cell 2001;12(6):1775-89.
2001: Julia Reichelt; Heinrich Büssow; Christine Grund; Thomas M Magin
Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice.
Molecular biology of the cell 2001;12(6):1557-68.
2001: Bettina Peters; Hans Wilhelm Kaiser; Thomas M Magin
Skin-specific expression of ank-3(93), a novel ankyrin-3 splice variant.
The Journal of investigative dermatology 2001;116(2):216-23.
2000: Thomas M Magin; Hans Wilhelm Kaiser; S Leitgeb; Christine Grund; Irene M Leigh; Susan M Morley; E Birgitte Lane
Supplementation of a mutant keratin by stable expression of desmin in cultured human EBS keratinocytes.
Journal of cell science 2000;113 Pt 23():4231-9.
2000: M Hesse; T Franz; Y Tamai; M M Taketo; Thomas M Magin
Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality.
The EMBO journal 2000;19(19):5060-70.
2000: Achim Plum; Gabi Hallas; Thomas M Magin; Frank Dombrowski; Andreas Hagendorff; Burghard Schumacher; Christian Wolpert; Jung Sun Kim; Wouter H Lamers; Matthias Evert; Paolo Meda; Otto Traub; Klaus Willecke
Unique and shared functions of different connexins in mice.
Current biology : CB 2000;10(18):1083-91.
2000: Martin Theis; Thomas M Magin; Achim Plum; Klaus Willecke
General or cell type-specific deletion and replacement of connexin-coding DNA in the mouse.
Methods (San Diego, Calif.) 2000;20(2):205-18.
1999: Rolf Schröder; Irene A P Warlo; Harald Herrmann; Peter F.M. van der Ven; C Klasen; Ingmar Blümcke; Rustam R Mundegar; Dieter O Fürst; Hans H Goebel; Thomas M Magin
Immunogold EM reveals a close association of plectin and the desmin cytoskeleton in human skeletal muscle.
European journal of cell biology 1999;78(4):288-95.
1998: Ailing A Lie; Rolf Schröder; Ingmar Blümcke; Thomas M Magin; Otmar D Wiestler; Christian E Elger
Plectin in the human central nervous system: predominant expression at pia/glia and endothelia/glia interfaces.
Acta neuropathologica 1998;96(3):215-21.
1998: Rebecca M Porter; Julia Reichelt; Declan P Lunny; Thomas M Magin; E Birgitte Lane
The relationship between hyperproliferation and epidermal thickening in a mouse model for BCIE.
The Journal of investigative dermatology 1998;110(6):951-7.
1998: Thomas M Magin; Rolf Schröder; S Leitgeb; F Wanninger; K Zatloukal; Christine Grund; D W Melton
Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates.
The Journal of cell biology 1998;140(6):1441-51.
1998: Thomas M Magin
Lessons from keratin transgenic and knockout mice.
Sub-cellular biochemistry 1998;31():141-72.
1997: Rolf Schröder; Rustam R Mundegar; M Treusch; U Schlegel; Ingmar Blümcke; K Owaribe; Thomas M Magin
Altered distribution of plectin/HD1 in dystrophinopathies.
European journal of cell biology 1997;74(2):165-71.
1996: Rebecca M Porter; S Leitgeb; David W Melton; O Swensson; R A Eady; Thomas M Magin
Gene targeting at the mouse cytokeratin 10 locus: severe skin fragility and changes of cytokeratin expression in the epidermis.
The Journal of cell biology 1996;132(5):925-36.
1992: Thomas M Magin; C McEwan; M Milne; A M Pow; Jim Selfridge; David W Melton
A position- and orientation-dependent element in the first intron is required for expression of the mouse hprt gene in embryonic stem cells.
Gene 1992;122(2):289-96.
1992: Thomas M Magin; jim mcwhir; David W Melton
A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency.
Nucleic acids research 1992;20(14):3795-6.
1992: Jim Selfridge; A M Pow; jim mcwhir; Thomas M Magin; David W Melton
Gene targeting using a mouse HPRT minigene/HPRT-deficient embryonic stem cell system: inactivation of the mouse ERCC-1 gene.
Somatic cell and molecular genetics 1992;18(4):325-36.
1991: B L Bader; Thomas M Magin; M Freudenmann; S Stumpp; Werner W Franke
Intermediate filaments formed de novo from tail-less cytokeratins in the cytoplasm and in the nucleus.
The Journal of cell biology 1991;115(5):1293-307.
1990: K Owaribe; Jürgen Kartenbeck; S Stumpp; Thomas M Magin; T Krieg; L A Diaz; Werner W Franke
The hemidesmosomal plaque. I. Characterization of a major constituent protein as a differentiation marker for certain forms of epithelia.
Differentiation; research in biological diversity 1990;45(3):207-20.
1990: Thomas M Magin; B L Bader; M Freudenmann; Werner W Franke
De novo formation of cytokeratin filaments in calf lens cells and cytoplasts after transfection with cDNAs or microinjection with mRNAs encoding human cytokeratins.
European journal of cell biology 1990;53(2):333-48.
1987: Thomas M Magin; M Hatzfeld; Werner W Franke
Analysis of cytokeratin domains by cloning and expression of intact and deleted polypeptides in Escherichia coli.
The EMBO journal 1987;6(9):2607-15.
1986: B L Bader; Thomas M Magin; M Hatzfeld; Werner W Franke
Amino acid sequence and gene organization of cytokeratin no. 19, an exceptional tail-less intermediate filament protein.
The EMBO journal 1986;5(8):1865-75.
1986: Thomas M Magin; J L Jorcano; Werner W Franke
Cytokeratin expression in simple epithelia. II. cDNA cloning and sequence characteristics of bovine cytokeratin A (no. 8).
Differentiation; research in biological diversity 1986;30(3):254-64.
1986: V Romano; M Hatzfeld; Thomas M Magin; Ralf Zimbelmann; Werner W Franke; G Maier; Herwig Ponstingl
Cytokeratin expression in simple epithelia. I. Identification of mRNA coding for human cytokeratin no. 18 by a cDNA clone.
Differentiation; research in biological diversity 1986;30(3):244-53.
1985: R A Quinlan; D L Schiller; M Hatzfeld; T Achtstätter; R Moll; J L Jorcano; Thomas M Magin; Werner W Franke
Patterns of expression and organization of cytokeratin intermediate filaments.
Annals of the New York Academy of Sciences 1985;455():282-306.
1984: J L Jorcano; Thomas M Magin; W W Franke
Cell type-specific expression of bovine keratin genes as demonstrated by the use of complementary DNA clones.
Journal of molecular biology 1984;176(1):21-37.
1983: A Venetianer; D L Schiller; Thomas M Magin; W W Franke
Cessation of cytokeratin expression in a rat hepatoma cell line lacking differentiated functions.
Nature 1983;305(5936):730-3.
1983: Thomas M Magin; J L Jorcano; Werner W Franke
Translational products of mRNAs coding for non-epidermal cytokeratins.
The EMBO journal 1983;2(8):1387-92.