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Graham Maguire

Research Profile

Chemicals & Drugs

Disorders

Lecithin Acyltransferase Deficiency

Procedures

Co-author Network

Publications

TOP 3
Lauren Hager; Mohammad A Hossain; Lixin Li; Lu Liu; Lilia Magomedova; Graham F Maguire; Mark Naples; Khosrow Adeli; Chris Baker; Philip W Connelly; Carolyn L Cummins; Henry Pun; Jonathan Tam; Dominic S Ng
Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice.
Philip W Connelly; Graham F Maguire; Clive M Picardo; John F Teiber; Dragomir I Draganov
Development of an immunoblot assay with infrared fluorescence to quantify paraoxonase 1 in serum and plasma.
Philip W Connelly; Dragomir I Draganov; Graham F Maguire
Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite.

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All Publications

2012: Lauren Hager; Mohammad A Hossain; Lixin Li; Lu Liu; Lilia Magomedova; Graham F Maguire; Mark Naples; Khosrow Adeli; Chris Baker; Philip W Connelly; Carolyn L Cummins; Henry Pun; Jonathan Tam; Dominic S Ng
Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice.
The Journal of biological chemistry 2012;287(24):20755-68.
2008: Philip W Connelly; Graham F Maguire; Clive M Picardo; John F Teiber; Dragomir I Draganov
Development of an immunoblot assay with infrared fluorescence to quantify paraoxonase 1 in serum and plasma.
Journal of lipid research 2008;49(1):245-50.
2005: Philip W Connelly; Dragomir I Draganov; Graham F Maguire
Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite.
Free radical biology & medicine 2005;38(2):164-74.
2004: Xianghong Zhu; Andrew Herzenberg; Mohammad Eskandarian; Graham F Maguire; James W Scholey; Philip W Connelly; Dominic S Ng
A novel in vivo lecithin-cholesterol acyltransferase (LCAT)-deficient mouse expressing predominantly LpX is associated with spontaneous glomerulopathy.
The American journal of pathology 2004;165(4):1269-78.
2004: Philip W Connelly; Graham F Maguire; Dragomir I Draganov
Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity.
Journal of lipid research 2004;45(3):561-6.
2004: Dominic S Ng; Chunhui Xie; Graham F Maguire; Xianghong Zhu; Francisca Ugwu; Eric Lam; Philip W Connelly
Hypertriglyceridemia in lecithin-cholesterol acyltransferase-deficient mice is associated with hepatic overproduction of triglycerides, increased lipogenesis, and improved glucose tolerance.
The Journal of biological chemistry 2004;279(9):7636-42.
2003: Zakaria Ahmed; Amir Ravandi; Graham F Maguire; Arnis Kuksis; Philip W Connelly
Formation of apolipoprotein AI-phosphatidylcholine core aldehyde Schiff base adducts promotes uptake by THP-1 macrophages.
Cardiovascular research 2003;58(3):712-20.
2003: Zakaria Ahmed; Saeid Babaei; Graham F Maguire; Dragomir I Draganov; Arnis Kuksis; Bert N La Du; Philip W Connelly
Paraoxonase-1 reduces monocyte chemotaxis and adhesion to endothelial cells due to oxidation of palmitoyl, linoleoyl glycerophosphorylcholine.
Cardiovascular research 2003;57(1):225-31.
2002: Dominic S Ng; Graham F Maguire; John Wylie; Amir Ravandi; Wanli Xuan; Zakaria Ahmed; Mohammad Eskandarian; Arnis Kuksis; Philip W Connelly
Oxidative stress is markedly elevated in lecithin:cholesterol acyltransferase-deficient mice and is paradoxically reversed in the apolipoprotein E knockout background in association with a reduction in atherosclerosis.
The Journal of biological chemistry 2002;277(14):11715-20.
2002: Zakaria Ahmed; Amir Ravandi; Graham F Maguire; Andrew Emili; Dragomir I Draganov; Bert N La Du; Arnis Kuksis; Philip W Connelly
Multiple substrates for paraoxonase-1 during oxidation of phosphatidylcholine by peroxynitrite.
Biochemical and biophysical research communications 2002;290(1):391-6.
2001: Zakaria Ahmed; Amir Ravandi; Graham F Maguire; Andrew Emili; Dragomir I Draganov; Bert N La Du; Arnis Kuksis; Philip W Connelly
Apolipoprotein A-I promotes the formation of phosphatidylcholine core aldehydes that are hydrolyzed by paraoxonase (PON-1) during high density lipoprotein oxidation with a peroxynitrite donor.
The Journal of biological chemistry 2001;276(27):24473-81.
2001: R A Guy; Graham F Maguire; Ian Crandall; Philip W Connelly; Kevin Kain
Characterization of peroxynitrite-oxidized low density lipoprotein binding to human CD36.
Atherosclerosis 2001;155(1):19-28.
1999: Ian Crandall; R A Guy; Graham F Maguire; Philip W Connelly; Kevin Kain
Plasmodium falciparum-infected erythrocytes and oxidized low-density lipoprotein bind to separate domains of CD36.
The Journal of infectious diseases 1999;180(2):473-9.
1997: Amrit K Kang; David J A Jenkins; T M Wolever; M W Huff; Graham F Maguire; Philip W Connelly; Robert A Hegele
Apolipoprotein E R112; R251G: a carboxy-terminal variant found in patients with hyperlipidemia and coronary heart disease.
Mutation research 1997;382(1-2):57-65.
1996: P W Connelly; C Vezina; Graham F Maguire
Quantification of apolipoprotein C-II by immunochemical and chromatographic methods.
Methods in enzymology 1996;263():188-208.
1994: P W Connelly; Graham F Maguire; C Vezina; Robert A Hegele; Arnis Kuksis
Kinetics of lipolysis of very low density lipoproteins by lipoprotein lipase. Importance of particle number and noncompetitive inhibition by particles with low triglyceride content.
The Journal of biological chemistry 1994;269(32):20554-60.
1993: P W Connelly; Graham F Maguire; C Vezina; Robert A Hegele; JA Little
Identification of disulfide-linked apolipoprotein species in human lipoproteins.
Journal of lipid research 1993;34(10):1717-27.
1993: Murray W Huff; Cynthia G Sawyez; P W Connelly; Graham F Maguire; JA Little; Robert A Hegele
Beta-VLDL in hepatic lipase deficiency induces apoE-mediated cholesterol ester accumulation in macrophages.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(9):1282-90.
1993: A J Evans; Cynthia G Sawyez; Bernard M Wolfe; P W Connelly; Graham F Maguire; Murray W Huff
Evidence that cholesteryl ester and triglyceride accumulation in J774 macrophages induced by very low density lipoprotein subfractions occurs by different mechanisms.
Journal of lipid research 1993;34(5):703-17.
1993: Robert A Hegele; JA Little; C Vezina; Graham F Maguire; L Tu; T S Wolever; David J A Jenkins; P W Connelly
Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(5):720-8.
1992: Robert A Hegele; L Tu; Graham F Maguire; P W Connelly
Molecular basis and allele specific screening of apolipoprotein CIISt. Michael.
Clinical biochemistry 1992;25(5):309-12.
1991: Robert A Hegele; W C Breckenridge; D W Cox; Graham F Maguire; JA Little; P W Connelly
Interaction between variant apolipoproteins C-II and E that affects plasma lipoprotein concentrations.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(5):1303-9.
1991: Robert A Hegele; P W Connelly; Graham F Maguire; Murray W Huff; L Leiter; Bernard M Wolfe; A J Evans; JA Little
An apolipoprotein CII mutation, CIILys19----Thr' identified in patients with hyperlipidemia.
Disease markers 1991;9(2):73-80.
1990: Murray W Huff; A J Evans; Bernard M Wolfe; P W Connelly; Graham F Maguire; W L Strong
Identification and metabolic characteristics of an apolipoprotein C-II variant isolated from a hypertriglyceridemic subject.
Journal of lipid research 1990;31(3):385-96.
1990: P W Connelly; Graham F Maguire; M Lee; JA Little
Plasma lipoproteins in familial hepatic lipase deficiency.
Arteriosclerosis (Dallas, Tex.) 1990;10(1):40-8.
1989: Graham F Maguire; M Lee; P W Connelly
Sodium dodecyl sulfate-glycerol polyacrylamide slab gel electrophoresis for the resolution of apolipoproteins.
Journal of lipid research 1989;30(5):757-61.
1988: P W Connelly; S Ranganathan; Graham F Maguire; M Lee; J J Myher; B A Kottke; Arnis Kuksis; JA Little
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
The Journal of biological chemistry 1988;263(28):14184-8.
1987: P W Connelly; Graham F Maguire; JA Little
Apolipoprotein CIISt. Michael. Familial apolipoprotein CII deficiency associated with premature vascular disease.
The Journal of clinical investigation 1987;80(6):1597-606.
1987: P W Connelly; Graham F Maguire; T Hofmann; JA Little
Structure of apolipoprotein C-IIToronto, a nonfunctional human apolipoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(1):270-3.
1984: Graham F Maguire; JA Little; G Kakis; W C Breckenridge
Apolipoprotein C-II deficiency associated with nonfunctional mutant forms of apolipoprotein C-II.
Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire 1984;62(9):847-52.
1982: D Hewitt; J Milner; A R Owen; W C Breckenridge; Graham F Maguire; G J Jones; JA Little
The inheritance of sinking-pre-beta lipoprotein and its relation to the Lp(a) antigen.
Clinical genetics 1982;21(5):301-8.