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Don Mahad

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Disorders

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Gene Deletion

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Publications

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G R Campbell; T M Polvikoski; A Reeve; R Reynolds; R W Taylor; D M Turnbull; Iryna Ziabreva; Don J Mahad
Mitochondrial DNA deletions and depletion within paraspinal muscles.
Hans Lassmann; Jack van Horssen; Don J Mahad
Progressive multiple sclerosis: pathology and pathogenesis.
Graham R Campbell; Konstantin Khrapko; Yevgenya Kraytsberg; Kim J Krishnan; Hans Lassmann; Jia Newcombe; Nobuhiko Ohno; Amy Reeve; Richard Reynolds; Bruce D Trapp; Doug M Turnbull; Iryna Ziabreva; Don J Mahad
Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis.

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All Publications

2013: G R Campbell; T M Polvikoski; A Reeve; R Reynolds; R W Taylor; D M Turnbull; Iryna Ziabreva; Don J Mahad
Mitochondrial DNA deletions and depletion within paraspinal muscles.
Neuropathology and applied neurobiology 2013;39(4):377-89.
2012: Hans Lassmann; Jack van Horssen; Don J Mahad
Progressive multiple sclerosis: pathology and pathogenesis.
Nature reviews. Neurology 2012;8(11):647-56.
2012: Graham R Campbell; Konstantin Khrapko; Yevgenya Kraytsberg; Kim J Krishnan; Hans Lassmann; Jia Newcombe; Nobuhiko Ohno; Amy Reeve; Richard Reynolds; Bruce D Trapp; Doug M Turnbull; Iryna Ziabreva; Don J Mahad
Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis.
Acta neuropathologica 2012;124(2):209-20.
2012: Graham R Campbell; Don J Mahad
Clonal expansion of mitochondrial DNA deletions and the progression of multiple sclerosis.
CNS & neurological disorders drug targets 2012;11(5):589-97.
2012: Graham R Campbell; Nobuhiko Ohno; Doug M Turnbull; Don J Mahad
Mitochondrial changes within axons in multiple sclerosis: an update.
Current opinion in neurology 2012;25(3):221-30.
2012: Nichola Z Lax; Emma L Blakely; Eduardo Bonilla; Graham R Campbell; Salvatore DiMauro; Evelyn Jaros; Hans Lassmann; Nobuhiko Ohno; Amy K Reeve; Kurenai Tanji; Robert W Taylor; Doug M Turnbull; Jessica Zambonin; Don J Mahad
Loss of myelin-associated glycoprotein in kearns-sayre syndrome.
Archives of neurology 2012;69(4):490-9.
2012: Marie T Fischer; Josa M Frischer; Lukas Haider; Jamie L Lim; Don J Mahad; Rakhi Sharma; Jack van Horssen; Monika Bradl; Joost A R Drexhage; Hans Lassmann
NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury.
Brain : a journal of neurology 2012;135(Pt 3):886-99.
2012: Graham R Campbell; Don J Mahad
Mitochondrial changes associated with demyelination: consequences for axonal integrity.
Mitochondrion 2012;12(2):173-9.
2011: Jessica L Zambonin; Chao Zhao; Iryna Ziabreva; Graham R Campbell; Sarah Engeham; Robin J M Franklin; Josa M Frischer; Hans Lassmann; Sok Ee Lee; Nobuhiko Ohno; Nadine Schwarz; Bruce D Trapp; Doug M Turnbull; Don J Mahad
Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis.
Brain : a journal of neurology 2011;134(Pt 7):1901-13.
2011: Graham R Campbell; Iryna Ziabreva; Amy K Reeve; Kim J Krishnan; Richard Reynolds; Owen Howell; Hans Lassmann; Doug M Turnbull; Don J Mahad
Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis.
Annals of neurology 2011;69(3):481-92.
2011: Graham R Campbell; Don J Mahad
Mitochondria as crucial players in demyelinated axons: lessons from neuropathology and experimental demyelination.
Autoimmune diseases 2011;2011():262847.
2009: Don J Mahad; Iryna Ziabreva; Graham Campbell; Nichola Lax; Katherine White; Peter S Hanson; Hans Lassmann; Douglass M Turnbull
Mitochondrial changes within axons in multiple sclerosis.
Brain : a journal of neurology 2009;132(Pt 5):1161-74.
2006: Don J Mahad; Melissa K Callahan; Katherine A Williams; Eroboghene E Ubogu; Pia Kivisäkk; Barbara Tucky; Grahame J Kidd; Gillian A Kingsbury; Ansi Chang; Robert J Fox; Matthias Mack; M Bradley Sniderman; Rivka Ravid; Susan M Staugaitis; Monique F Stins; Richard M Ransohoff
Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis.
Brain : a journal of neurology 2006;129(Pt 1):212-23.
2005: Orhun H Kantarci; Yazmín Morales; Patricia A Ziemer; David D Hebrink; Don J Mahad; Elizabeth J Atkinson; Sara J Achenbach; Mariza de Andrade; Matthias Mack; Richard M Ransohoff; Hans Lassmann; Wolfgang Bruck; Brian G Weinshenker; Claudia F Lucchinetti
CCR5Delta32 polymorphism effects on CCR5 expression, patterns of immunopathology and disease course in multiple sclerosis.
Journal of neuroimmunology 2005;169(1-2):137-43.
2005: Don J Mahad; Susan M Staugaitis; Paul M Ruggieri; Joseph E Parisi; BK Kleinschmidt-DeMasters; Hans Lassmann; Richard M Ransohoff
Steroid-responsive encephalopathy associated with autoimmune thyroiditis and primary CNS demyelination.
Journal of the neurological sciences 2005;228(1):3-5.
2004: Pia Kivisäkk; Don J Mahad; Melissa K Callahan; Keith Sikora; Corinna Trebst; Barbara Tucky; Jerome R Wujek; Rivka Ravid; Susan M Staugaitis; Hans Lassmann; Richard M Ransohoff
Expression of CCR7 in multiple sclerosis: implications for CNS immunity.
Annals of neurology 2004;55(5):627-38.
2004: Don J Mahad; Corinna Trebst; Pia Kivisäkk; Susan M Staugaitis; Barbara Tucky; Tao Wei; Claudia F Lucchinetti; Hans Lassmann; Richard M Ransohoff
Expression of chemokine receptors CCR1 and CCR5 reflects differential activation of mononuclear phagocytes in pattern II and pattern III multiple sclerosis lesions.
Journal of neuropathology and experimental neurology 2004;63(3):262-73.
2004: Don J Mahad; Corinna Trebst; Susan M Staugaitis; Pia Kivisäkk; Barbara Tucky; Tao Wei; Richard Horuk; Richard M Ransohoff
Preliminary observations on CC chemokine receptor expression by mononuclear phagocytes in multiple sclerosis lesions: effect of lesion heterogeneity.
Ernst Schering Research Foundation workshop 2004;(45):59-68.
2003: Pia Kivisäkk; Don J Mahad; Melissa K Callahan; Corinna Trebst; Barbara Tucky; Tao Wei; Lijun Wu; Espen S Baekkevold; Hans Lassmann; Susan M Staugaitis; James J Campbell; Richard M Ransohoff
Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8389-94.
2003: Arockia Doss; Don J Mahad; C A J Romanowski
Wernicke encephalopathy: unusual findings in nonalcoholic patients.
Journal of computer assisted tomography 2003;27(2):235-40.
2003: Corinna Trebst; Susan M Staugaitis; Pia Kivisäkk; Don J Mahad; Martha K Cathcart; Barbara Tucky; Tao Wei; Mysore R Sandhya Rani; Richard Horuk; Kenneth Aldape; CARLOS PARDO-VILLAMIZAR; Claudia F Lucchinetti; Hans Lassmann; Richard M Ransohoff
CC chemokine receptor 8 in the central nervous system is associated with phagocytic macrophages.
The American journal of pathology 2003;162(2):427-38.
2003: Don J Mahad; Richard M Ransohoff
The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE).
Seminars in immunology 2003;15(1):23-32.
2002: Bernd C Kieseier; Marie Tani; Don J Mahad; Nobuyuki Oka; Ho W Tony; Nicola Woodroofe; John W Griffin; Klaus V Toyka; Richard M Ransohoff; Hans-Peter Hartung
Chemokines and chemokine receptors in inflammatory demyelinating neuropathies: a central role for IP-10.
Brain : a journal of neurology 2002;125(Pt 4):823-34.