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Ghulam Maharvi

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TOP 3
Ghulam M Maharvi; Adil E Bharucha; Abdul Fauq
Synthesis of a DOTA (Gd3+)-conjugate of proton-pump inhibitor pantoprazole for gastric wall imaging studies.
Samer Abdul-Hay; Juliette Bertrand; Thomas R Caulfield; Shakeel Choudhry; Clémence Claussin; Abdul Fauq; Amy L Lane; Ghulam M Maharvi; Amandine Masson; Malcolm Leissring
Optimization of peptide hydroxamate inhibitors of insulin-degrading enzyme reveals marked substrate-selectivity.
Veena Beri; Abdul Fauq; Ghulam M Maharvi; Jeffrey T Auletta; Juanita F Wood; Terrone L Rosenberry
Hydrolysis of low concentrations of the acetylthiocholine analogs acetyl(homo)thiocholine and acetyl(nor)thiocholine by acetylcholinesterase may be limited by selective gating at the enzyme peripheral site.

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All Publications

2013: Ghulam M Maharvi; Adil E Bharucha; Abdul Fauq
Synthesis of a DOTA (Gd3+)-conjugate of proton-pump inhibitor pantoprazole for gastric wall imaging studies.
Bioorganic & medicinal chemistry letters 2013;23(9):2808-11.
2013: Samer Abdul-Hay; Juliette Bertrand; Thomas R Caulfield; Shakeel Choudhry; Clémence Claussin; Abdul Fauq; Amy L Lane; Ghulam M Maharvi; Amandine Masson; Malcolm Leissring
Optimization of peptide hydroxamate inhibitors of insulin-degrading enzyme reveals marked substrate-selectivity.
Journal of medicinal chemistry 2013;56(6):2246-55.
2013: Veena Beri; Abdul Fauq; Ghulam M Maharvi; Jeffrey T Auletta; Juanita F Wood; Terrone L Rosenberry
Hydrolysis of low concentrations of the acetylthiocholine analogs acetyl(homo)thiocholine and acetyl(nor)thiocholine by acetylcholinesterase may be limited by selective gating at the enzyme peripheral site.
Chemico-biological interactions 2013;203(1):38-43.
2011: P Bourassa; S Dubeau; Abdul H Fauq; Ghulam M Maharvi; T J Thomas; Heidar-Ali Tajmir-Riahi
Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albumin.
European journal of medicinal chemistry 2011;46(9):4344-53.
2011: P Bourassa; S Dubeau; Ghulam M Maharvi; Abdul H Fauq; T J Thomas; Heidar-Ali Tajmir-Riahi
Binding of antitumor tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen to human serum albumin.
Biochimie 2011;93(7):1089-101.
2010: Abdul Fauq; Ghulam M Maharvi; Dola Sinha
A convenient synthesis of (Z)-4-hydroxy-N-desmethyltamoxifen (endoxifen).
Bioorganic & medicinal chemistry letters 2010;20(10):3036-8.
2010: Malcolm Leissring; Enrico Malito; Sabrine Hedouin; Lael Reinstatler; Tomoko Sahara; Samer Abdul-Hay; Shakeel Choudhry; Ghulam M Maharvi; Abdul Fauq; Malwina Huzarska; Philip S May; Sungwoon Choi; Todd P Logan; Benjamin E Turk; Lewis C Cantley; Marika Manolopoulou; Wei-Jen Tang; Ross L Stein; Gregory D Cuny; Dennis J Selkoe
Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.
PloS one 2010;5(5):e10504.
2009: Vijayaraghavan Rangachari; Zachary S Davey; Brent Healy; Brenda D Moore; Leilani K Sonoda; Bernadette Cusack; Ghulam M Maharvi; Abdul Fauq; Terrone L Rosenberry
Rationally designed dehydroalanine (DeltaAla)-containing peptides inhibit amyloid-beta (Abeta) peptide aggregation.
Biopolymers 2009;91(6):456-65.
2009: S Ali; Nighat Afza; M Lateef; Ghulam M Maharvi; A Malik; A U Rehman; Naheed Riaz; L Iqbal
Lipoxygenase inhibitory tetraketones: potential remedial source for inflammation and asthma.
The West Indian medical journal 2009;58(2):92-8.
2009: Khalid M Khan; Muhammad Zarrar Khan; Muhammad Taha; Ghulam M Maharvi; Zafar S Saify; Shahnaz Parveen; Muhammad Iqbal Choudhary
Leishmanicidal potential of N-substituted morpholine derivatives: synthesis and structure-activity relationships.
Natural product research 2009;23(5):479-84.
2008: Thomas L Kukar; Thomas B Ladd; Maralyssa A Bann; Patrick C Fraering; Rajeshwar Narlawar; Ghulam M Maharvi; Brent Healy; Robert Chapman; Alfred T Welzel; Robert W Price; Brenda Moore; Vijayaraghavan Rangachari; Bernadette Cusack; Jason Eriksen; Karen Jansen-West; Christophe Verbeeck; Debra Yager; Christopher B Eckman; Wenjuan Ye; Sarah A Sagi; Barbara A Cottrell; Justin Torpey; Terrone L Rosenberry; Abdul Fauq; Michael S Wolfe; Boris Schmidt; Dominic M Walsh; Edward H Koo; todd golde
Substrate-targeting gamma-secretase modulators.
Nature 2008;453(7197):925-9.
2008: Ghulam M Maharvi; Samar Ali; Naheed Riaz; Nighat Afza; Abdul Malik; Muhammad Ashraf; Lubna Iqbal; Mehreen Lateef
Mild and efficient synthesis of new tetraketones as lipoxygenase inhibitors and antioxidants.
Journal of enzyme inhibition and medicinal chemistry 2008;23(1):62-9.
2007: Abdul Fauq; Katherine Simpson; Ghulam M Maharvi; todd golde; Pritam Das
A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers.
Bioorganic & medicinal chemistry letters 2007;17(22):6392-5.
2006: Khalid M Khan; Zafar S Saify; Muhammad Arif Lodhi; Naeem Butt; Shahnaz Perveen; Ghulam M Maharvi; M Iqbal Choudhary
Piperidines: a new class of urease inhibitors.
Natural product research 2006;20(6):523-30.
2006: Khalid M Khan; Ghulam M Maharvi; Mahmud Tareq Hassan Khan; Ahson Jabbar Shaikh; Shahnaz Perveen; Saeedan Begum; M Iqbal Choudhary
Tetraketones: a new class of tyrosinase inhibitors.
Bioorganic & medicinal chemistry 2006;14(2):344-51.
2005: Khalid M Khan; Zafar S Saify; Mahmud Tareq Hassan Khan; Naeem Butt; Ghulam M Maharvi; Shahnaz Perveen; Nida Ambreen; M Iqbal Choudhary; Claudiu T Supuran
Tyrosinase inhibition: conformational analysis based studies on molecular dynamics calculations of bipiperidine based inhibitors.
Journal of enzyme inhibition and medicinal chemistry 2005;20(4):401-7.
2005: Khalid M Khan; Ghulam M Maharvi; Shahnaz Perveen; Mahmud Tareq Hassan Khan; Raid J Abdel-Jalil; Syed Tasadaque Ali Shah; Miriam Fecker; M Iqbal Choudhary; Wolfgang Voelter
Synthesis of methyl ether analogues of sildenafil (Viagra) possessing tyrosinase inhibitory potential.
Chemistry & biodiversity 2005;2(4):470-6.
2005: Aurangzeb Hasan; Khalid M Khan; Mohammed Sher; Ghulam M Maharvi; Sarfraz Ahmad Nawaz; M Iqbal Choudhary; Claudiu T Supuran
Synthesis and inhibitory potential towards acetylcholinesterase, butyrylcholinesterase and lipoxygenase of some variably substituted chalcones.
Journal of enzyme inhibition and medicinal chemistry 2005;20(1):41-7.
2005: Khalid M Khan; Ghulam M Maharvi; Mahmud Tareq Hassan Khan; Shahnaz Perveen; M Iqbal Choudhary
A facile and improved synthesis of sildenafil (Viagra) analogs through solid support microwave irradiation possessing tyrosinase inhibitory potential, their conformational analysis and molecular dynamics simulation studies.
Molecular diversity 2005;9(1-3):15-26.
2004: Khalid M Khan; Sajid Iqbal; Muhammad Arif Lodhi; Ghulam M Maharvi; Shahnaz Perveen; M Iqbal Choudhary; Zahid H Chohan; Claudiu T Supuran
Synthesis and urease enzyme inhibitory effects of some dicoumarols.
Journal of enzyme inhibition and medicinal chemistry 2004;19(4):367-71.
2004: Khalid M Khan; Sajid Iqbal; Muhammad Arif Lodhi; Ghulam M Maharvi; Zia Ullah; M Iqbal Choudhary; Atta ur Rahman; Shahnaz Perveen
Biscoumarin: new class of urease inhibitors; economical synthesis and activity.
Bioorganic & medicinal chemistry 2004;12(8):1963-8.
2004: Zahid H Chohan; Humayun Pervez; Abdul Rauf; Khalid M Khan; Ghulam M Maharvi; Claudiu T Supuran
Antibacterial and antifugal mono- and di-substituted symmetrical and unsymmetrical triazine-derived Schiff-bases and their transition metal complexes.
Journal of enzyme inhibition and medicinal chemistry 2004;19(2):161-8.
2004: Zahid H Chohan; Humayun Pervez; Khalid M Khan; Abdul Rauf; Ghulam M Maharvi; Claudiu T Supuran
Antifungal cobalt(II), copper(II), nickel(II) and zinc(II) complexes of furanyl-,thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins.
Journal of enzyme inhibition and medicinal chemistry 2004;19(1):85-90.