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Jacquelyn Maher

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Nizar A Mukhtar; Jacquelyn J Maher; Jennifer Melgar; Claudia E Ayala; Peter Bacchetti; Spencer Christensen; Mandana Khalili
Insulin sensitivity and variability in hepatitis C virus infection using direct measurement.
Vanja Varenika; Miguel C Cabarrus; Yanjun Fu; Dongwei Gao; Sanjay Kakar; Jacquelyn J Maher; Benjamin M Yeh
Hepatic fibrosis: evaluation with semiquantitative contrast-enhanced CT.
Chunyue Yin; Kimberley J Evason; Jacquelyn J Maher; Didier Y R Stainier
The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: analysis of stellate cell entry into the developing liver.

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All Publications

2013: Nizar A Mukhtar; Jacquelyn J Maher; Jennifer Melgar; Claudia E Ayala; Peter Bacchetti; Spencer Christensen; Mandana Khalili
Insulin sensitivity and variability in hepatitis C virus infection using direct measurement.
Digestive diseases and sciences 2013;58(4):1141-8.
2013: Vanja Varenika; Miguel C Cabarrus; Yanjun Fu; Dongwei Gao; Sanjay Kakar; Jacquelyn J Maher; Benjamin M Yeh
Hepatic fibrosis: evaluation with semiquantitative contrast-enhanced CT.
Radiology 2013;266(1):151-8.
2012: Chunyue Yin; Kimberley J Evason; Jacquelyn J Maher; Didier Y R Stainier
The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: analysis of stellate cell entry into the developing liver.
Hepatology (Baltimore, Md.) 2012;56(5):1958-70.
2012: Danielle Brandman; Claudia E Ayala; Peter Bacchetti; Jacquelyn J Maher; Mandana Khalili
Impact of insulin resistance on HCV treatment response and impact of HCV treatment on insulin sensitivity using direct measurements of insulin action.
Diabetes care 2012;35(5):1090-4.
2011: Jacquelyn J Maher
New insights from rodent models of fatty liver disease.
Antioxidants & redox signaling 2011;15(2):535-50.
2010: Russell K Soon; Jim S Yan; James P Grenert; Jacquelyn J Maher
Stress signaling in the methionine-choline-deficient model of murine fatty liver disease.
Gastroenterology 2010;139(5):1730-9, 1739.e1.
2010: Michael K Pickens; Hisanobu Ogata; Russell K Soon; James P Grenert; Jacquelyn J Maher
Dietary fructose exacerbates hepatocellular injury when incorporated into a methionine-choline-deficient diet.
Liver international : official journal of the International Association for the Study of the Liver 2010;30(8):1229-39.
2010: Khoa D Lam; Peter Bacchetti; Fahim Abbasi; Claudia E Ayala; Samuel M Loeb; Vidhi Shah; Michael J Wen; Gerald M Reaven; Jacquelyn J Maher; Mandana Khalili
Comparison of surrogate and direct measurement of insulin resistance in chronic hepatitis C virus infection: impact of obesity and ethnicity.
Hepatology (Baltimore, Md.) 2010;52(1):38-46.
2010: Jacquelyn J Maher
Trunk fat as a determinant of liver disease.
Gastroenterology 2010;138(4):1244-6.
2010: Claus U Niemann; Fengyun Xu; Soojinna Choi; Matthias Behrends; Yeonho Park; Ryutaro Hirose; Jacquelyn J Maher
Short passive cooling protects rats during hepatectomy by inducing heat shock proteins and limiting the induction of pro-inflammatory cytokines.
The Journal of surgical research 2010;158(1):43-52.
2009: Michael K Pickens; Jim S Yan; Raymond K Ng; Hisanobu Ogata; James P Grenert; Carine Beysen; Scott M Turner; Jacquelyn J Maher
Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis.
Journal of lipid research 2009;50(10):2072-82.
2009: Jacquelyn J Maher
DAMPs ramp up drug toxicity.
The Journal of clinical investigation 2009;119(2):246-9.
2008: Jacquelyn J Maher; Pablo Leon; James C Ryan
Beyond insulin resistance: Innate immunity in nonalcoholic steatohepatitis.
Hepatology (Baltimore, Md.) 2008;48(2):670-8.
2007: Mingxiang Liao; Michael K Pabarcus; YongQiang Wang; Colleen Hefner; David A Maltby; Katalin F Medzihradszky; Saida Patricia Salas-Castillo; James Yan; Jacquelyn J Maher; Maria Almira Correia
Impaired dexamethasone-mediated induction of tryptophan 2,3-dioxygenase in heme-deficient rat hepatocytes: translational control by a hepatic eIF2alpha kinase, the heme-regulated inhibitor.
The Journal of pharmacology and experimental therapeutics 2007;323(3):979-89.
2007: Gene S Lee; Jim S Yan; Raymond K Ng; Sanjay Kakar; Jacquelyn J Maher
Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury.
Journal of lipid research 2007;48(8):1885-96.
2007: Saadia Faouzi; Katalin F Medzihradszky; Colleen Hefner; Jacquelyn J Maher; Maria Almira Correia
Characterization of the physiological turnover of native and inactivated cytochromes P450 3A in cultured rat hepatocytes: a role for the cytosolic AAA ATPase p97?
Biochemistry 2007;46(26):7793-803.
2007: Jacquelyn J Maher
Alcoholic steatohepatitis: management and prognosis.
Current gastroenterology reports 2007;9(1):39-46.
2006: Gizem Rizki; Lorenzo Arnaboldi; Bianca Gabrielli; Jim Yan; Gene S Lee; Ray K Ng; Scott M Turner; Thomas M Badger; Robert E Pitas; Jacquelyn J Maher
Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1.
Journal of lipid research 2006;47(10):2280-90.
2006: Claus U Niemann; Soojinna Choi; Matthias Behrends; Ryutaro Hirose; Joonhwa Noh; John L Coatney; John P Roberts; Natalie J Serkova; Jacquelyn J Maher
Mild hypothermia protects obese rats from fulminant hepatic necrosis induced by ischemia-reperfusion.
Surgery 2006;140(3):404-12.
2006: Pratima Kodali; Ping Wu; Parshawn A Lahiji; Eric J Brown; Jacquelyn J Maher
ANIT toxicity toward mouse hepatocytes in vivo is mediated primarily by neutrophils via CD18.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(2):G355-63.
2006: Betty Y Y Tam; Kevin Wei; John S Rudge; Jana Hoffman; Jocelyn Holash; Sang-ki Park; Jenny Yuan; Colleen Hefner; Cecile Chartier; Jeng-Shin Lee; Shelly Jiang; Nihar R Nayak; Nihar R Niyak; Frans A Kuypers; Lisa Ma; Uma Sundram; Grace Wu; Joseph A Garcia; Stanley L Schrier; Jacquelyn J Maher; Randall S Johnson; George D Yancopoulos; Richard C Mulligan; Calvin J Kuo
VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis.
Nature medicine 2006;12(7):793-800.
2006: Jan Hirsch; Kirk Hansen; Soojinna Choi; Joonhwa Noh; Ryutaro Hirose; John P Roberts; Michael A Matthay; Al L Burlingame; Jacquelyn J Maher; Claus U Niemann
Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats.
Molecular & cellular proteomics : MCP 2006;5(6):979-86.
2006: Natalie J Serkova; Matthew R Jackman; Jaimi L Brown; Tao Liu; Ryutaro Hirose; John P Roberts; Jacquelyn J Maher; Claus U Niemann
Metabolic profiling of livers and blood from obese Zucker rats.
Journal of hepatology 2006;44(5):956-62.
2006: Jennifer C Hanson; Michele K Bostick; Carson B Campe; Pratima Kodali; Gene Lee; Jim Yan; Jacquelyn J Maher
Transgenic overexpression of interleukin-8 in mouse liver protects against galactosamine/endotoxin toxicity.
Journal of hepatology 2006;44(2):359-67.
2005: Xing-Mei Han; Gene Lee; Colleen Hefner; Jacquelyn J Maher; Maria Almira Correia
Heme-reversible impairment of CYP2B1/2 induction in heme-depleted rat hepatocytes in primary culture: translational control by a hepatic alpha-subunit of the eukaryotic initiation factor kinase?
The Journal of pharmacology and experimental therapeutics 2005;314(1):128-38.
2004: Junquan Xu; Gene Lee; Haimei Wang; John M Vierling; Jacquelyn J Maher
Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injury.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(3):G734-41.
2004: Jacquelyn J Maher
What doesn't kill you makes you stronger: how hepatocytes survive prolonged cholestasis.
Hepatology (Baltimore, Md.) 2004;39(4):1141-3.
2002: Jacquelyn J Maher
Treatment of alcoholic hepatitis.
Journal of gastroenterology and hepatology 2002;17(4):448-55.
2002: Johan Björkegren; Anne P Beigneux; Martin O Bergo; Jacquelyn J Maher; Stephen G Young
Blocking the secretion of hepatic very low density lipoproteins renders the liver more susceptible to toxin-induced injury.
The Journal of biological chemistry 2002;277(7):5476-83.
2002: Jacquelyn J Maher
Alcoholic steatosis and steatohepatitis.
Seminars in gastrointestinal disease 2002;13(1):31-9.
2001: Saadia Faouzi; B E Burckhardt; J C Hanson; C B Campe; Laura W Schrum; Richard A Rippe; Jacquelyn J Maher
Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway.
The Journal of biological chemistry 2001;276(52):49077-82.
2001: sabrina sonda; Li-Min Ting; S Novak; Kami Kim; Jacquelyn J Maher; Robert V Farese; Joel D Ernst
Cholesterol esterification by host and parasite is essential for optimal proliferation of Toxoplasma gondii.
The Journal of biological chemistry 2001;276(37):34434-40.
2001: R Wang; L D Ferrell; Saadia Faouzi; Jacquelyn J Maher; John M Bishop
Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice.
The Journal of cell biology 2001;153(5):1023-34.
2000: J M Saito; Jacquelyn J Maher
Bile duct ligation in rats induces biliary expression of cytokine-induced neutrophil chemoattractant.
Gastroenterology 2000;118(6):1157-68.
1999: Jacquelyn J Maher
Leukocytes as modulators of stellate cell activation.
Alcoholism, clinical and experimental research 1999;23(5):917-21.
1999: Jacquelyn J Maher
Cytokines: overview.
Seminars in liver disease 1999;19(2):109-15.
1998: Jacquelyn J Maher; J S Lozier; M K Scott
Rat hepatic stellate cells produce cytokine-induced neutrophil chemoattractant in culture and in vivo.
The American journal of physiology 1998;275(4 Pt 1):G847-53.
1997: Jacquelyn J Maher; B A Neuschwander-Tetri
Manipulation of glutathione stores in rat hepatic stellate cells does not alter collagen synthesis.
Hepatology (Baltimore, Md.) 1997;26(3):618-23.
1997: Jacquelyn J Maher; J M Saito; B A Neuschwander-Tetri
Glutathione regulation in rat hepatic stellate cells. Comparative studies in primary culture and in liver injury in vivo.
Biochemical pharmacology 1997;53(5):637-41.
1997: Jacquelyn J Maher; M K Scott; J M Saito; Melissa Burton
Adenovirus-mediated expression of cytokine-induced neutrophil chemoattractant in rat liver induces a neutrophilic hepatitis.
Hepatology (Baltimore, Md.) 1997;25(3):624-30.
1997: Jacquelyn J Maher
Exploring alcohol's effects on liver function.
Alcohol health and research world 1997;21(1):5-12.
1995: Jacquelyn J Maher
Rat hepatocytes and Kupffer cells interact to produce interleukin-8 (CINC) in the setting of ethanol.
The American journal of physiology 1995;269(4 Pt 1):G518-23.
1994: Jacquelyn J Maher; C Tzagarakis; A Giménez
Malondialdehyde stimulates collagen production by hepatic lipocytes only upon activation in primary culture.
Alcohol and alcoholism (Oxford, Oxfordshire) 1994;29(5):605-10.
1994: Jacquelyn J Maher; S Zia; C Tzagarakis
Acetaldehyde-induced stimulation of collagen synthesis and gene expression is dependent on conditions of cell culture: studies with rat lipocytes and fibroblasts.
Alcoholism, clinical and experimental research 1994;18(2):403-9.
1994: Jacquelyn J Maher; C Tzagarakis
Partial cloning of the M subunit of laminin from adult rat lipocytes: expression of the M subunit by cells isolated from normal and injured liver.
Hepatology (Baltimore, Md.) 1994;19(3):764-70.
1993: Jacquelyn J Maher; D Montgomery Bissell
Cell-matrix interactions in liver.
Seminars in cell biology 1993;4(3):189-201.
1993: Jacquelyn J Maher
Cell-specific expression of hepatocyte growth factor in liver. Upregulation in sinusoidal endothelial cells after carbon tetrachloride.
The Journal of clinical investigation 1993;91(5):2244-52.
1993: Jacquelyn J Maher; S L Friedman
Parenchymal and nonparenchymal cell interactions in the liver.
Seminars in liver disease 1993;13(1):13-20.
1992: Don C Rockey; Jacquelyn J Maher; William R Jarnagin; G Gabbiani; S L Friedman
Inhibition of rat hepatic lipocyte activation in culture by interferon-gamma.
Hepatology (Baltimore, Md.) 1992;16(3):776-84.
1992: S L Friedman; Don C Rockey; R F McGuire; Jacquelyn J Maher; J K Boyles; G Yamasaki
Isolated hepatic lipocytes and Kupffer cells from normal human liver: morphological and functional characteristics in primary culture.
Hepatology (Baltimore, Md.) 1992;15(2):234-43.
1992: Jacquelyn J Maher
Yet another role for the "good" matrix protein: laminin in regenerating liver.
Hepatology (Baltimore, Md.) 1992;15(1):164-6.
1990: Jacquelyn J Maher; R F McGuire
Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo.
The Journal of clinical investigation 1990;86(5):1641-8.
1990: D Montgomery Bissell; S L Friedman; Jacquelyn J Maher; F J Roll
Connective tissue biology and hepatic fibrosis: report of a conference.
Hepatology (Baltimore, Md.) 1990;11(3):488-98.
1990: Jacquelyn J Maher
Hepatic fibrosis caused by alcohol.
Seminars in liver disease 1990;10(1):66-74.
1989: Jacquelyn J Maher
Fat-storing cells and myofibroblasts: one cell or two?
Hepatology (Baltimore, Md.) 1989;9(6):903-4.
1988: Jacquelyn J Maher
Primary hepatocyte culture: is it home away from home?
Hepatology (Baltimore, Md.) 1988;8(5):1162-6.
1988: Jacquelyn J Maher; D Montgomery Bissell; S L Friedman; F J Roll
Collagen measured in primary cultures of normal rat hepatocytes derives from lipocytes within the monolayer.
The Journal of clinical investigation 1988;82(2):450-9.
1988: Jacquelyn J Maher; S L Friedman; F J Roll; D Montgomery Bissell
Immunolocalization of laminin in normal rat liver and biosynthesis of laminin by hepatic lipocytes in primary culture.
Gastroenterology 1988;94(4):1053-62.
1987: D Montgomery Bissell; D M Arenson; Jacquelyn J Maher; F J Roll
Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver.
The Journal of clinical investigation 1987;79(3):801-12.