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Jonathan Maher

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Jonathan M Maher; Lauren M Aleksunes; Matthew Z Dieter; Yuji Tanaka; Jeffrey M Peters; José E Manautou; Curtis D Klaassen
Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid.
Matthew D Merrell; Jonathan P Jackson; Lisa M Augustine; Craig D Fisher; Angela L Slitt; Jonathan M Maher; Wendong Huang; David D Moore; Youcai Zhang; Curtis D Klaassen; Nathan J Cherrington
The Nrf2 activator oltipraz also activates the constitutive androstane receptor.
Yuji Tanaka; Chuan Chen; Jonathan M Maher; Curtis D Klaassen
Ischemia-reperfusion of rat livers decreases liver and increases kidney multidrug resistance associated protein 2 (Mrp2).

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2008: Jonathan M Maher; Lauren M Aleksunes; Matthew Z Dieter; Yuji Tanaka; Jeffrey M Peters; José E Manautou; Curtis D Klaassen
Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid.
Toxicological sciences : an official journal of the Society of Toxicology 2008;106(2):319-28.
2008: Matthew D Merrell; Jonathan P Jackson; Lisa M Augustine; Craig D Fisher; Angela L Slitt; Jonathan M Maher; Wendong Huang; David D Moore; Youcai Zhang; Curtis D Klaassen; Nathan J Cherrington
The Nrf2 activator oltipraz also activates the constitutive androstane receptor.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(8):1716-21.
2008: Yuji Tanaka; Chuan Chen; Jonathan M Maher; Curtis D Klaassen
Ischemia-reperfusion of rat livers decreases liver and increases kidney multidrug resistance associated protein 2 (Mrp2).
Toxicological sciences : an official journal of the Society of Toxicology 2008;101(1):171-8.
2008: Lauren M Aleksunes; Angela L Slitt; Jonathan M Maher; Lisa M Augustine; Michael Goedken; Jefferson Y Chan; Nathan J Cherrington; Curtis D Klaassen; José E Manautou
Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2.
Toxicology and applied pharmacology 2008;226(1):74-83.
2007: Jonathan M Maher; Matthew Z Dieter; Lauren M Aleksunes; Angela L Slitt; Grace Guo; Yuji Tanaka; George L Scheffer; Jefferson Y Chan; José E Manautou; Ying Chen; Timothy P Dalton; Masayuki Yamamoto; Curtis D Klaassen
Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway.
Hepatology (Baltimore, Md.) 2007;46(5):1597-610.
2007: Craig D Fisher; Lisa M Augustine; Jonathan M Maher; David M Nelson; Angela L Slitt; Curtis D Klaassen; Lois D Lehman-McKeeman; Nathan J Cherrington
Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(6):995-1000.
2007: Yuji Tanaka; Jonathan M Maher; Chuan Chen; Curtis D Klaassen
Hepatic ischemia-reperfusion induces renal heme oxygenase-1 via NF-E2-related factor 2 in rats and mice.
Molecular pharmacology 2007;71(3):817-25.
2007: Angela L Slitt; Katryn Allen; Jennifer Morrone; Lauren M Aleksunes; Chuan Chen; Jonathan M Maher; José E Manautou; Nathan J Cherrington; Curtis D Klaassen
Regulation of transporter expression in mouse liver, kidney, and intestine during extrahepatic cholestasis.
Biochimica et biophysica acta 2007;1768(3):637-47.
2006: Jonathan M Maher; Angela L Slitt; T N Callaghan; Xingguo Cheng; C Cheung; F J Gonzalez; Curtis D Klaassen
Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha.
Biochemical pharmacology 2006;72(4):512-22.
2006: Yuji Tanaka; Chuan Chen; Jonathan M Maher; Curtis D Klaassen
Kupffer cell-mediated downregulation of hepatic transporter expression in rat hepatic ischemia-reperfusion.
Transplantation 2006;82(2):258-66.
2006: Jonathan M Maher; Xingguo Cheng; Yuji Tanaka; George L Scheffer; Curtis D Klaassen
Hormonal regulation of renal multidrug resistance-associated proteins 3 and 4 (Mrp3 and Mrp4) in mice.
Biochemical pharmacology 2006;71(10):1470-8.
2006: Jeffrey S Moffit; Lauren M Aleksunes; Jonathan M Maher; George L Scheffer; Curtis D Klaassen; José E Manautou
Induction of hepatic transporters multidrug resistance-associated proteins (Mrp) 3 and 4 by clofibrate is regulated by peroxisome proliferator-activated receptor alpha.
The Journal of pharmacology and experimental therapeutics 2006;317(2):537-45.
2006: Jonathan M Maher; Nathan J Cherrington; Angela L Slitt; Curtis D Klaassen
Tissue distribution and induction of the rat multidrug resistance-associated proteins 5 and 6.
Life sciences 2006;78(19):2219-25.
2006: Lauren M Aleksunes; Angela L Slitt; Jonathan M Maher; Matthew Z Dieter; Tamara R Knight; Michael Goedken; Nathan J Cherrington; Jefferson Y Chan; Curtis D Klaassen; José E Manautou
Nuclear factor-E2-related factor 2 expression in liver is critical for induction of NAD(P)H:quinone oxidoreductase 1 during cholestasis.
Cell stress & chaperones 2006;11(4):356-63.
2005: Jonathan M Maher; Xingguo Cheng; Angela L Slitt; Matthew Z Dieter; Curtis D Klaassen
Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(7):956-62.
2005: Jonathan M Maher; Angela L Slitt; Nathan J Cherrington; Xingguo Cheng; Curtis D Klaassen
Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(7):947-55.
2005: Yuji Tanaka; Angela L Slitt; Tyra M Leazer; Jonathan M Maher; Curtis D Klaassen
Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice.
Biochemical and biophysical research communications 2005;326(1):181-7.
2004: Matthew Z Dieter; Jonathan M Maher; Xingguo Cheng; Curtis D Klaassen
Expression and regulation of the sterol half-transporter genes ABCG5 and ABCG8 in rats.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2004;139(4):209-18.
2003: Nathan J Cherrington; Angela L Slitt; Jonathan M Maher; Xiao-Xue Zhang; Jun Zhang; Wendong Huang; Yu-Jui Yvonne Wan; David D Moore; Curtis D Klaassen
Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(11):1315-9.
2003: Angela L Slitt; Nathan J Cherrington; Jonathan M Maher; Curtis D Klaassen
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(9):1176-86.