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Megan Maher

Research Profile

Procedures

X Ray Crystallography

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Chemicals & Drugs

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Publications

TOP 3
Chandrika N Deshpande; Josep Font; Amy P Guilfoyle; Megan J Maher; Aaron P McGrath; Mika Jormakka
Structure of an atypical FeoB G-domain reveals a putative domain-swapped dimer.
Ulrike Kappler; Megan J Maher
The bacterial SoxAX cytochromes.
Elise M Laming; J Mitchell Guss; Ulrike Kappler; Aaron P McGrath; Megan J Maher
The X-ray crystal structure of a pseudoazurin from Sinorhizobium meliloti.

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All Publications

2013: Chandrika N Deshpande; Josep Font; Amy P Guilfoyle; Megan J Maher; Aaron P McGrath; Mika Jormakka
Structure of an atypical FeoB G-domain reveals a putative domain-swapped dimer.
Acta crystallographica. Section F, Structural biology and crystallization communications 2013;69(Pt 4):399-404.
2013: Ulrike Kappler; Megan J Maher
The bacterial SoxAX cytochromes.
Cellular and molecular life sciences : CMLS 2013;70(6):977-92.
2012: Elise M Laming; J Mitchell Guss; Ulrike Kappler; Aaron P McGrath; Megan J Maher
The X-ray crystal structure of a pseudoazurin from Sinorhizobium meliloti.
Journal of inorganic biochemistry 2012;115():148-54.
2012: Miriam-Rose Ash; Megan J Maher; J Mitchell Guss; Mika Jormakka
The cation-dependent G-proteins: in a class of their own.
FEBS letters 2012;586(16):2218-24.
2011: Miriam Rose Ash; J Mitchell Guss; Megan J Maher; Mika Jormakka
The structure of an N11A mutant of the G-protein domain of FeoB.
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 12):1511-5.
2011: Miriam Rose Ash; J Mitchell Guss; Megan J Maher; Mika Jormakka
A suite of Switch I and Switch II mutant structures from the G-protein domain of FeoB.
Acta crystallographica. Section D, Biological crystallography 2011;67(Pt 11):973-80.
2011: Miriam-Rose Ash; Lee Xin Chong; Mark G Hinds; Megan J Maher; Zhiguang Xiao; Anthony G Wedd
Molecular basis of the cooperative binding of Cu(I) and Cu(II) to the CopK protein from Cupriavidus metallidurans CH34.
Biochemistry 2011;50(43):9237-47.
2011: Miriam-Rose Ash; J Mitchell Guss; Megan J Maher; Mika Jormakka
The initiation of GTP hydrolysis by the G-domain of FeoB: insights from a transition-state complex structure.
PloS one 2011;6(8):e23355.
2009: Lee Xin Chong; Miriam-Rose Ash; Megan J Maher; Mark G Hinds; Zhiguang Xiao; Anthony G Wedd
Unprecedented binding cooperativity between Cu(I) and Cu(II) in the copper resistance protein CopK from Cupriavidus metallidurans CH34: implications from structural studies by NMR spectroscopy and X-ray crystallography.
Journal of the American Chemical Society 2009;131(10):3549-64.
2007: Mihwa Lee; Megan J Maher; Richard I Christopherson; J Mitchell Guss
Kinetic and structural analysis of mutant Escherichia coli dihydroorotases: a flexible loop stabilizes the transition state.
Biochemistry 2007;46(37):10538-50.
2007: Mihwa Lee; Camilla W Chan; Stephen C Graham; Richard I Christopherson; J Mitchell Guss; Megan J Maher
Structures of ligand-free and inhibitor complexes of dihydroorotase from Escherichia coli: implications for loop movement in inhibitor design.
Journal of molecular biology 2007;370(5):812-25.
2007: Mihwa Lee; Megan J Maher; J Mitchell Guss
Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-fluoroorotate: catalytic activity is reflected by the crystal form.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 3):154-61.
2006: Lianyi Zhang; Melissa Koay; Megan J Maher; Zhiguang Xiao; Anthony G Wedd
Intermolecular transfer of copper ions from the CopC protein of Pseudomonas syringae. Crystal structures of fully loaded Cu(I)Cu(II) forms.
Journal of the American Chemical Society 2006;128(17):5834-50.
2005: Melissa Koay; Lianyi Zhang; Binsheng Yang; Megan J Maher; Zhiguang Xiao; Anthony G Wedd
CopC protein from Pseudomonas syringae: intermolecular transfer of copper from both the copper(I) and copper(II) sites.
Inorganic chemistry 2005;44(15):5203-5.
2005: Mihwa Lee; Camilla W Chan; J Mitchell Guss; Richard I Christopherson; Megan J Maher
Dihydroorotase from Escherichia coli: loop movement and cooperativity between subunits.
Journal of molecular biology 2005;348(3):523-33.
2004: Stephen C Graham; Megan J Maher; William H Simmons; Hans C Freeman; J Mitchell Guss
Structure of Escherichia coli aminopeptidase P in complex with the inhibitor apstatin.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 10):1770-9.
2004: Janet E Deane; Daniel P Ryan; Margaret Sunde; Megan J Maher; J Mitchell Guss; Jane E Visvader; Jacqueline M Matthews
Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex.
The EMBO journal 2004;23(18):3589-98.
2004: Megan J Maher; Mousumi Ghosh; Amy M Grunden; Angeli Lal Menon; Michael W W Adams; Hans C Freeman; J Mitchell Guss
Structure of the prolidase from Pyrococcus furiosus.
Biochemistry 2004;43(10):2771-83.
2004: Megan J Maher; Joanne Santini; Ingrid J Pickering; Roger C Prince; Joan M Macy; Graham Neil George
X-ray absorption spectroscopy of selenate reductase.
Inorganic chemistry 2004;43(2):402-4.
2003: Mihwa Lee; Megan J Maher; Hans C Freeman; J Mitchell Guss
Auracyanin B structure in space group P6(5).
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 9):1545-50.
2003: Janet E Deane; Megan J Maher; David B Langley; Stephen C Graham; Jane E Visvader; J Mitchell Guss; Jacqueline M Matthews
Crystallization of FLINC4, an intramolecular LMO4-ldb1 complex.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 8):1484-6.
2003: Megan J Maher; Danny T Huang; J Mitchell Guss; Charles A Collyer; Richard I Christopherson
Crystallization of hamster dihydroorotase: involvement of a disulfide-linked tetrameric form.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 2):381-4.
2002: Mihwa Lee; Katrina Willingham; David B Langley; Megan J Maher; Aina E Cohen; Paul J Ellis; Jason A Kuchar; David M Dooley; Hans C Freeman; J Mitchell Guss
Crystallization of Pichia pastoris lysyl oxidase.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 12):2177-9.
2002: Megan J Maher; Joan M Macy
Crystallization and preliminary X-ray analysis of the selenate reductase from Thauera selenatis.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 4):706-8.
2001: Katrina Willingham; Megan J Maher; Amy M Grunden; Mousumi Ghosh; Michael W W Adams; Hans C Freeman; J Mitchell Guss
Crystallization and characterization of the prolidase from Pyrococcus furiosus.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 3):428-30.
2001: Charles Bond; Robert E Blankenship; Hans C Freeman; J Mitchell Guss; Megan J Maher; Fabiola M Selvaraj; Matthew C J Wilce; Katrina Willingham
Crystal structure of auracyanin, a "blue" copper protein from the green thermophilic photosynthetic bacterium Chloroflexus aurantiacus.
Journal of molecular biology 2001;306(1):47-67.
2000: Zhiguang Xiao; Megan J Maher; Maddalena Cross; Charles Bond; J Mitchell Guss; Anthony G Wedd
Mutation of the surface valine residues 8 and 44 in the rubredoxin from Clostridium pasteurianum: solvent access versus structural changes as determinants of reversible potential.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2000;5(1):75-84.
1999: Megan J Maher; Zhiguang Xiao; Matthew C J Wilce; J Mitchell Guss; Anthony G Wedd
Rubredoxin from Clostridium pasteurianum. Structures of G10A, G43A and G10VG43A mutant proteins. Mutation of conserved glycine 10 to valine causes the 9-10 peptide link to invert.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 5):962-8.
1999: P S Brereton; Megan J Maher; Peter A Tregloan; Anthony G Wedd
Investigation of the role of surface residues in the ferredoxin from Clostridium pasteurianum.
Biochimica et biophysica acta 1999;1429(2):307-16.