FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Iftekhar Mahmood

Research Profile

Physiology

Phenomena

Concepts & Ideas

Living Beings

Chemicals & Drugs

Procedures

Administration, Oral

Co-author Network

Publications

TOP 3
Iftekhar Mahmood
Prediction of drug concentration-time profiles of therapeutic proteins in humans from animals.
Iftekhar Mahmood
Evaluation of sigmoidal maturation and allometric models: prediction of propofol clearance in neonates and infants.
Iftekhar Mahmood
Prediction of clearance and volume of distribution in the obese from normal weight subjects: an allometric approach.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Iftekhar Mahmood (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Iftekhar Mahmood
Prediction of drug concentration-time profiles of therapeutic proteins in humans from animals.
Xenobiotica; the fate of foreign compounds in biological systems 2013;43(2):153-60.
2013: Iftekhar Mahmood
Evaluation of sigmoidal maturation and allometric models: prediction of propofol clearance in neonates and infants.
American journal of therapeutics 2013;20(1):21-8.
2012: Iftekhar Mahmood
Prediction of clearance and volume of distribution in the obese from normal weight subjects: an allometric approach.
Clinical pharmacokinetics 2012;51(8):527-42.
2012: Iftekhar Mahmood; Kosalaram Goteti
Prediction of drug concentration-time data in humans from animals: a comparison of three methods.
Xenobiotica; the fate of foreign compounds in biological systems 2012;42(8):756-65.
2011: Iftekhar Mahmood
Pharmacokinetic allometric scaling of oligonucleotides.
Nucleic acid therapeutics 2011;21(5):315-21.
2011: Iftekhar Mahmood
A comparison of simple allometric and maturation models for the prediction of morphine clearance in pediatrics.
Drug metabolism and drug interactions 2011;26(2):71-7.
2011: Iftekhar Mahmood
Evaluation of a morphine maturation model for the prediction of morphine clearance in children: how accurate is the predictive performance of the model?
British journal of clinical pharmacology 2011;71(1):88-94.
2010: Iftekhar Mahmood
Theoretical versus empirical allometry: Facts behind theories and application to pharmacokinetics.
Journal of pharmaceutical sciences 2010;99(7):2927-33.
2010: Iftekhar Mahmood
Prediction of drug clearance in children 3 months and younger: an allometric approach.
Drug metabolism and drug interactions 2010;25(1-4):25-34.
2009: M Martinez; Iftekhar Mahmood; Robert P Hunter
Allometric scaling of clearance in dogs.
Journal of veterinary pharmacology and therapeutics 2009;32(5):411-6.
2009: Iftekhar Mahmood
Pharmacokinetic allometric scaling of antibodies: application to the first-in-human dose estimation.
Journal of pharmaceutical sciences 2009;98(10):3850-61.
2009: Iftekhar Mahmood
Role of fixed coefficients and exponents in the prediction of human drug clearance: how accurate are the predictions from one or two species?
Journal of pharmaceutical sciences 2009;98(7):2472-93.
2009: Iftekhar Mahmood
Application of fixed exponent 0.75 to the prediction of human drug clearance: an inaccurate and misleading concept.
Drug metabolism and drug interactions 2009;24(1):57-81.
2007: Iftekhar Mahmood; Martin David Green
Drug interaction studies of therapeutic proteins or monoclonal antibodies.
Journal of clinical pharmacology 2007;47(12):1540-54.
2007: Iftekhar Mahmood
Application of allometric principles for the prediction of pharmacokinetics in human and veterinary drug development.
Advanced drug delivery reviews 2007;59(11):1177-92.
2006: M Martinez; Iftekhar Mahmood; Robert P Hunter
Interspecies allometric scaling: prediction of clearance in large animal species: part II: mathematical considerations.
Journal of veterinary pharmacology and therapeutics 2006;29(5):425-32.
2006: Iftekhar Mahmood; M Martinez; Robert P Hunter
Interspecies allometric scaling. Part I: prediction of clearance in large animals.
Journal of veterinary pharmacology and therapeutics 2006;29(5):415-23.
2006: Iftekhar Mahmood
Prediction of human drug clearance from animal data: application of the rule of exponents and 'fu Corrected Intercept Method' (FCIM).
Journal of pharmaceutical sciences 2006;95(8):1810-21.
2006: Iftekhar Mahmood
Prediction of drug clearance in children from adults: a comparison of several allometric methods.
British journal of clinical pharmacology 2006;61(5):545-57.
2005: Iftekhar Mahmood
Interspecies scaling of biliary excreted drugs: a comparison of several methods.
Journal of pharmaceutical sciences 2005;94(4):883-92.
2005: Iftekhar Mahmood; Martin D Green
Pharmacokinetic and pharmacodynamic considerations in the development of therapeutic proteins.
Clinical pharmacokinetics 2005;44(4):331-47.
2004: Iftekhar Mahmood; VK Tammara
A comparison of two sparse sampling population pharmacokinetic approaches for the estimation of pharmacokinetic parameters in children.
International journal of clinical pharmacology and therapeutics 2004;42(4):240-5.
2004: Iftekhar Mahmood
Estimation of absorption rate constant (ka) following oral administration by Wagner-Nelson, Loo-Riegelman, and statistical moments in the presence of a secondary peak.
Drug metabolism and drug interactions 2004;20(1-2):85-100.
2004: Iftekhar Mahmood
Impact of truncated area under the curve on failed bioequivalence studies: a computer simulation analysis.
Drug metabolism and drug interactions 2004;20(1-2):77-83.
2004: Iftekhar Mahmood
Interspecies scaling of protein drugs: prediction of clearance from animals to humans.
Journal of pharmaceutical sciences 2004;93(1):177-85.
2003: Iftekhar Mahmood
Center specificity in the limited sampling model (LSM): can the LSM developed from healthy subjects be extended to disease states?
International journal of clinical pharmacology and therapeutics 2003;41(11):517-23.
2003: Iftekhar Mahmood
Impact of random and fixed (optimal) sampling approach on the Bayesian estimation of clearance.
International journal of clinical pharmacology and therapeutics 2003;41(9):392-6.
2003: Iftekhar Mahmood; Martin David Green; J Edward Fisher
Selection of the first-time dose in humans: comparison of different approaches based on interspecies scaling of clearance.
Journal of clinical pharmacology 2003;43(7):692-7.
2003: Iftekhar Mahmood
A Bayesian approach for the estimation of pharmacokinetic parameters in children.
American journal of therapeutics 2003;10(2):88-92.
2002: Iftekhar Mahmood
Selegiline transdermal system Somerset.
Current opinion in investigational drugs (London, England : 2000) 2002;3(8):1230-3.
2002: Iftekhar Mahmood; Chandra Sahajwalla
Interspecies scaling of biliary excreted drugs.
Journal of pharmaceutical sciences 2002;91(8):1908-14.
2002: Iftekhar Mahmood
Comparison of different reduced sampling approaches for the estimation of pharmacokinetic parameters for long half-life drugs in patients with renal or hepatic impairment.
International journal of clinical pharmacology and therapeutics 2002;40(2):53-9.
2002: Iftekhar Mahmood
Prediction of clearance in humans from in vitro human liver microsomes and allometric scaling. A comparative study of the two approaches.
Drug metabolism and drug interactions 2002;19(1):49-64.
2002: Iftekhar Mahmood
Interspecies scaling: predicting oral clearance in humans.
American journal of therapeutics 2002;9(1):35-42.
2001: Iftekhar Mahmood
Interspecies scaling of inhalational anesthetic potency minimum alveolar concentration (MAC): application of a correction factor for the prediction of MAC in humans.
American journal of therapeutics 2001;8(4):237-41.
2001: Iftekhar Mahmood
Interspecies scaling of maximum tolerated dose of anticancer drugs: relevance to starting dose for phase I clinical trials.
American journal of therapeutics 2001;8(2):109-16.
2001: Iftekhar Mahmood
Interspecies scaling: is a priori knowledge of cytochrome p450 isozymes involved in drug metabolism helpful in prediction of clearance in humans from animal data?
Drug metabolism and drug interactions 2001;18(2):135-47.
2001: Iftekhar Mahmood
Application of preclinical data to initiate the modified continual reassessment method for maximum tolerated dose-finding trials.
Journal of clinical pharmacology 2001;41(1):19-24.
2000: Iftekhar Mahmood
Interspecies scaling: role of protein binding in the prediction of clearance from animals to humans.
Journal of clinical pharmacology 2000;40(12 Pt 2):1439-46.
2000: Iftekhar Mahmood
Limited sampling model for the estimation of pharmacokinetic parameters in children.
Therapeutic drug monitoring 2000;22(5):532-6.
2000: Iftekhar Mahmood
Critique of prospective allometric scaling: does the emperor have clothes?
Journal of clinical pharmacology 2000;40(4):341-4; discussion 345-6.
2000: Iftekhar Mahmood
Can absolute oral bioavailability in humans be predicted from animals? A comparison of allometry and different indirect methods.
Drug metabolism and drug interactions 2000;16(2):143-55.
1999: Iftekhar Mahmood
Allometric issues in drug development.
Journal of pharmaceutical sciences 1999;88(11):1101-6.
1999: Iftekhar Mahmood; R Miller
Comparison of the Bayesian approach and a limited sampling model for the estimation of AUC and Cmax: a computer simulation analysis.
International journal of clinical pharmacology and therapeutics 1999;37(9):439-45.
1999: Iftekhar Mahmood
Prediction of clearance, volume of distribution and half-life by allometric scaling and by use of plasma concentrations predicted from pharmacokinetic constants: a comparative study.
The Journal of pharmacy and pharmacology 1999;51(8):905-10.
1999: Iftekhar Mahmood; H Mahayni
A limited sampling approach in bioequivalence studies: application to long half-life drugs and replicate design studies.
International journal of clinical pharmacology and therapeutics 1999;37(6):275-81.
1999: Iftekhar Mahmood; Chandra Sahajwalla
Clinical pharmacokinetics and pharmacodynamics of buspirone, an anxiolytic drug.
Clinical pharmacokinetics 1999;36(4):277-87.
1999: Iftekhar Mahmood; R Yuan
A comparative study of allometric scaling with plasma concentrations predicted by species-invariant time methods.
Biopharmaceutics & drug disposition 1999;20(3):137-44.
1999: Iftekhar Mahmood; JD Balian
The pharmacokinetic principles behind scaling from preclinical results to phase I protocols.
Clinical pharmacokinetics 1999;36(1):1-11.
1998: Iftekhar Mahmood
Is 10 milligrams selegiline essential as an adjunct therapy for the symptomatic treatment of Parkinson's disease?
Therapeutic drug monitoring 1998;20(6):717-21.
1998: Iftekhar Mahmood
Simple method for the estimation of absorption rate constant(ka) after oral administration.
American journal of therapeutics 1998;5(6):377-81.
1998: Iftekhar Mahmood; VK Tammara; Raman K Baweja
Does percent reduction in seizure frequency correlate with plasma concentration of anticonvulsant drugs? Experience with four anticonvulsant drugs.
Clinical pharmacology and therapeutics 1998;64(5):547-52.
1998: Iftekhar Mahmood
Assessment of metabolites in bioequivalence studies: should bioequivalence criteria be applied on the sum of parent compound and metabolite?
International journal of clinical pharmacology and therapeutics 1998;36(10):540-4.
1998: Iftekhar Mahmood
Interspecies scaling: predicting volumes, mean residence time and elimination half-life. Some suggestions.
The Journal of pharmacy and pharmacology 1998;50(5):493-9.
1998: Iftekhar Mahmood
Development of a limited sampling approach in pharmacokinetic studies: experience with the antiepilepsy drug tiagabine.
Journal of clinical pharmacology 1998;38(4):324-30.
1998: Iftekhar Mahmood
Integration of in vitro data and brain weight in allometric scaling to predict clearance in humans: some suggestions.
Journal of pharmaceutical sciences 1998;87(4):527-9; discussion 530.
1998: Iftekhar Mahmood; N Chamberlin
A limited sampling method for the estimation of AUC and Cmax of carbamazepine and carbamazepine epoxide following a single and multiple dose of a sustained-release product.
British journal of clinical pharmacology 1998;45(3):241-6.
1998: Iftekhar Mahmood
Interspecies scaling of renally secreted drugs.
Life sciences 1998;63(26):2365-71.
1997: Iftekhar Mahmood
Prediction of absolute bioavailability for drugs using oral and renal clearance following a single oral dose: a critical view.
Biopharmaceutics & drug disposition 1997;18(6):465-73.
1997: Iftekhar Mahmood; N Chamberlin; VK Tammara
A limited sampling approach in bioequivalence studies.
Therapeutic drug monitoring 1997;19(4):413-9.
1997: Iftekhar Mahmood
Clinical pharmacokinetics and pharmacodynamics of selegiline. An update.
Clinical pharmacokinetics 1997;33(2):91-102.
1997: Iftekhar Mahmood
A comparative computer simulation study of three different sparse-sampling methods for the estimation of steady-state area under the concentration-time curve (AUC) and maximum concentration (Cmax) in toxicokinetics.
Journal of pharmaceutical sciences 1997;86(5):579-83.
1997: Iftekhar Mahmood; J T Sahlroot
A limited sampling method for the estimation of flunarizine area under the curve (AUC) and maximum plasma concentration (Cmax).
Biopharmaceutics & drug disposition 1997;18(2):117-26.
1997: VK Tammara; Iftekhar Mahmood; D K Yu; G A Hileman
A limited sampling method for the estimation of vigabatrin maximum plasma concentration and area under the curve.
Therapeutic drug monitoring 1997;19(1):79-82.
1996: Iftekhar Mahmood
Pharmacokinetic analysis of the absorption characteristics of diclofenac sodium in man by use of a multi-segment absorption model.
The Journal of pharmacy and pharmacology 1996;48(12):1260-3.
1996: Iftekhar Mahmood; JD Balian
Interspecies scaling: predicting clearance of drugs in humans. Three different approaches.
Xenobiotica; the fate of foreign compounds in biological systems 1996;26(9):887-95.
1996: Iftekhar Mahmood
Interspecies scaling: predicting clearance of anticancer drugs in humans. A comparative study of three different approaches using body weight or body surface area.
European journal of drug metabolism and pharmacokinetics 1996;21(3):275-8.
1996: Iftekhar Mahmood; JD Balian
Interspecies scaling: predicting pharmacokinetic parameters of antiepileptic drugs in humans from animals with special emphasis on clearance.
Journal of pharmaceutical sciences 1996;85(4):411-4.
1996: Iftekhar Mahmood; JD Balian
Interspecies scaling: a comparative study for the prediction of clearance and volume using two or more than two species.
Life sciences 1996;59(7):579-85.