Ravinder Maini

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Smolen J S; Han C; van der Heijde D M F M; Emery P; Bathon J M; Keystone E; Maini R N; Kalden J R; Aletaha D; Baker D; Han J; Bala M; St Clair E W;
Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the impacts of remission and tumour necrosis factor blockade.
Elliot Michael J; Maini Ravinder N; Feldmann Marc; Long-Fox Alice; Charles Peter; Katasikis Peter; Brennan Fionula M; Bijl Hanny; Ghrayeb John; Woody James N
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.
Hrynaszkiewicz Iain; Lipsky Peter E; Maini Ravinder N
Introducing Arthritis Research & Therapy's 10th anniversary issue, 'The Scientific Basis of Rheumatology: A Decade of Progress'.

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2009: Smolen J S; Han C; van der Heijde D M F M; Emery P; Bathon J M; Keystone E; Maini R N; Kalden J R; Aletaha D; Baker D; Han J; Bala M; St Clair E W;
Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the impacts of remission and tumour necrosis factor blockade.
Annals of the rheumatic diseases 2009;68(6):823-7.
2008: Elliot Michael J; Maini Ravinder N; Feldmann Marc; Long-Fox Alice; Charles Peter; Katasikis Peter; Brennan Fionula M; Bijl Hanny; Ghrayeb John; Woody James N
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.
Arthritis and rheumatism 2008;58(2 Suppl):S92-S101.
2008: Hrynaszkiewicz Iain; Lipsky Peter E; Maini Ravinder N
Introducing Arthritis Research & Therapy's 10th anniversary issue, 'The Scientific Basis of Rheumatology: A Decade of Progress'.
Arthritis research & therapy 2008;10(5):119.
2007: Maini Ravinder N; Feldmann Marc
The pitfalls in the development of biologic therapy.
Nature clinical practice. Rheumatology 2007;3(1):1.
2006: Maini R N; Taylor P C; Szechinski J; Pavelka K; Bröll J; Balint G; Emery P; Raemen F; Petersen J; Smolen J; Thomson D; Kishimoto T;
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate.
Arthritis and rheumatism 2006;54(9):2817-29.
2006: Smolen Josef S; Han Chenglong; van der Heijde Désirée; Emery Paul; Bathon Joan M; Keystone Edward; Kalden Joachim R; Schiff Michael; Bala Mohan; Baker Daniel; Han John; Maini Ravinder N; St Clair E William
Infliximab treatment maintains employability in patients with early rheumatoid arthritis.
Arthritis and rheumatism 2006;54(3):716-22.
2006: Smolen Josef S; Van Der Heijde Désirée M F M; St Clair E William; Emery Paul; Bathon Joan M; Keystone Edward; Maini Ravinder N; Kalden Joachim R; Schiff Michael; Baker Daniel; Han Chenglong; Han John; Bala Mohan;
Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial.
Arthritis and rheumatism 2006;54(3):702-10.
2006: Taylor P C; Steuer A; Gruber J; McClinton C; Cosgrove D O; Blomley M J K; Marsters P A; Wagner C L; Maini R N
Ultrasonographic and radiographic results from a two-year controlled trial of immediate or one-year-delayed addition of infliximab to ongoing methotrexate therapy in patients with erosive early rheumatoid arthritis.
Arthritis and rheumatism 2006;54(1):47-53.
2006: Smolen Josef S; Maini Ravinder N
Interleukin-6: a new therapeutic target.
Arthritis research & therapy 2006;8 Suppl 2():S5.
2005: Maini R N
The 2005 International Symposium on Advances in Targeted Therapies: what have we learned in the 2000s and where are we going?
Annals of the rheumatic diseases 2005;64 Suppl 4():iv106-8.
2005: Smolen J S; Han C; Bala M; Maini R N; Kalden J R; van der Heijde D; Breedveld F C; Furst D E; Lipsky P E;
Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: a detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study.
Arthritis and rheumatism 2005;52(4):1020-30.
2004: St Clair E William; van der Heijde Désirée M F M; Smolen Josef S; Maini Ravinder N; Bathon Joan M; Emery Paul; Keystone Edward; Schiff Michael; Kalden Joachim R; Wang Ben; Dewoody Kimberly; Weiss Roberta; Baker Daniel;
Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial.
Arthritis and rheumatism 2004;50(11):3432-43.
2004: Taylor P C; Steuer A; Gruber J; Cosgrove D O; Blomley M J K; Marsters P A; Wagner C L; McClinton C; Maini R N
Comparison of ultrasonographic assessment of synovitis and joint vascularity with radiographic evaluation in a randomized, placebo-controlled study of infliximab therapy in early rheumatoid arthritis.
Arthritis and rheumatism 2004;50(4):1107-16.
2004: Maini R N; Breedveld F C; Kalden J R; Smolen J S; Furst D; Weisman M H; St Clair E W; Keenan G F; van der Heijde D; Marsters P A; Lipsky P E;
Sustained improvement over two years in physical function, structural damage, and signs and symptoms among patients with rheumatoid arthritis treated with infliximab and methotrexate.
Arthritis and rheumatism 2004;50(4):1051-65.
2004: Feldmann Marc; Brennan Fionula M; Williams Richard O; Woody James N; Maini Ravinder N
The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis.
Best practice & research. Clinical rheumatology 2004;18(1):59-80.
2004: Maini Ravinder N
Current and new antitumor necrosis factor agents in perspective.
Arthritis research & therapy 2004;6 Suppl 2():S1-2.
2004: Feldmann Marc; Brennan Fionula M; Paleolog Ewa; Cope Andrew; Taylor Peter; Williams Richard; Woody Jim; Maini Ravinder N
Anti-TNFalpha therapy of rheumatoid arthritis: what can we learn about chronic disease?
Novartis Foundation symposium 2004;256():53-69; discussion 69-73, 106-11, 266-9.
2003: Fritzler Marvin J; Wiik Allan; Tan Eng M; Smolen Josef S; McDougal J Steven; Chan Edward K l; Gordon Thomas P; Hardin John A; Kalden Joachim R; Lahita Robert G; Maini Ravinder N; Reeves Westley H; Rothfield Naomi F; Takasaki Yoshinari; Wilson Merlin; Byrd Martha G; Slivka Lloyd; Koziol James A
A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. III. Comparative performance characteristics of academic and manufacturers' laboratories.
The Journal of rheumatology 2003;30(11):2374-81.
2003: Feldmann Marc; Maini Ravinder N
Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases.
Nature medicine 2003;9(10):1245-50.
2002: Lipsky Peter E; Felson David T; Maini Ravinder N
Blocking tumor necrosis factor inhibits radiographic damage even in patients who show minimal or no clinical improvement: comment on the concise communication by Boers.
Arthritis and rheumatism 2002;46(10):2817-8; author reply 2718-21.
2002: Andreakos Evangelos T; Foxwell Brian M; Brennan Fionula M; Maini Ravinder N; Feldmann Marc
Cytokines and anti-cytokine biologicals in autoimmunity: present and future.
Cytokine & growth factor reviews 2002;13(4-5):299-313.
2002: Vencovský J; Zd'árský E; Moyes S P; Hajeer A; Ruzicková S; Cimburek Z; Ollier W E; Maini R N; Mageed R A
Polymorphism in the immunoglobulin VH gene V1-69 affects susceptibility to rheumatoid arthritis in subjects lacking the HLA-DRB1 shared epitope.
Rheumatology (Oxford, England) 2002;41(4):401-10.
2002: Marinova-Mutafchieva L; Williams R O; Funa K; Maini R N; Zvaifler N J
Inflammation is preceded by tumor necrosis factor-dependent infiltration of mesenchymal cells in experimental arthritis.
Arthritis and rheumatism 2002;46(2):507-13.
2002: Feldmann Marc; Maini Ravinder N
Discovery of TNF-alpha as a therapeutic target in rheumatoid arthritis: preclinical and clinical studies.
Joint, bone, spine : revue du rhumatisme 2002;69(1):12-8.
2002: Tan Eng M; Smolen Josef S; McDougal J Steven; Fritzler Marvin J; Gordon Thomas; Hardin John A; Kalden Joachim R; Lahita Robert G; Maini Ravinder N; Reeves Westley H; Rothfield Naomi F; Takasaki Yoshinari; Wiik Allan; Wilson Merlin; Koziol James A
A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. II. Potential for quantitation of antibody content.
The Journal of rheumatology 2002;29(1):68-74.
2002: Maini Ravinder N; Feldmann Marc
How does infliximab work in rheumatoid arthritis?
Arthritis research 2002;4 Suppl 2():S22-8.
2001: Ballara S; Taylor P C; Reusch P; Marmé D; Feldmann M; Maini R N; Paleolog E M
Raised serum vascular endothelial growth factor levels are associated with destructive change in inflammatory arthritis.
Arthritis and rheumatism 2001;44(9):2055-64.
2001: Malfait A M; Williams R O; Malik A S; Maini R N; Feldmann M
Chronic relapsing homologous collagen-induced arthritis in DBA/1 mice as a model for testing disease-modifying and remission-inducing therapies.
Arthritis and rheumatism 2001;44(5):1215-24.
2001: Bondeson J; Maini R N
Tumour necrosis factor as a therapeutic target in rheumatoid arthritis and other chronic inflammatory diseases: the clinical experience with infliximab (REMICADE).
International journal of clinical practice 2001;55(3):211-6.
2001: Feldmann M; Maini R N; Bondeson J; Taylor P; Foxwell B M; Brennan F M
Cytokine blockade in rheumatoid arthritis.
Advances in experimental medicine and biology 2001;490():119-27.
2001: Feldmann M; Maini R N
Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?
Annual review of immunology 2001;19():163-96.
2000: Williams R O; Marinova-Mutafchieva L; Feldmann M; Maini R N
Evaluation of TNF-alpha and IL-1 blockade in collagen-induced arthritis and comparison with combined anti-TNF-alpha/anti-CD4 therapy.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7240-5.
2000: Charles P J; Smeenk R J; De Jong J; Feldmann M; Maini R N
Assessment of antibodies to double-stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor alpha: findings in open-label and randomized placebo-controlled trials.
Arthritis and rheumatism 2000;43(11):2383-90.
2000: Feldmann M; Miotla J; Paleolog E; Williams R; Malfait A M; Taylor P; Brennan F M; Maini R N
Future prospects for anti-cytokine treatment.
Annals of the rheumatic diseases 2000;59 Suppl 1():i119-22.
2000: Williams R O; Feldmann M; Maini R N
Cartilage destruction and bone erosion in arthritis: the role of tumour necrosis factor alpha.
Annals of the rheumatic diseases 2000;59 Suppl 1():i75-80.
2000: Marinova-Mutafchieva L; Taylor P; Funa K; Maini R N; Zvaifler N J
Mesenchymal cells expressing bone morphogenetic protein receptors are present in the rheumatoid arthritis joint.
Arthritis and rheumatism 2000;43(9):2046-55.
2000: Marinova-Mutafchieva L; Williams R O; Mauri C; Mason L J; Walmsley M J; Taylor P C; Feldmann M; Maini R N
A comparative study into the mechanisms of action of anti-tumor necrosis factor alpha, anti-CD4, and combined anti-tumor necrosis factor alpha/anti-CD4 treatment in early collagen-induced arthritis.
Arthritis and rheumatism 2000;43(3):638-44.
2000: Taylor P C; Peters A M; Paleolog E; Chapman P T; Elliott M J; McCloskey R; Feldmann M; Maini R N
Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis.
Arthritis and rheumatism 2000;43(1):38-47.
2000: Zvaifler N J; Marinova-Mutafchieva L; Adams G; Edwards C J; Moss J; Burger J A; Maini R N
Mesenchymal precursor cells in the blood of normal individuals.
Arthritis research 2000;2(6):477-88.
1999: Feldmann M; Maini R N
The role of cytokines in the pathogenesis of rheumatoid arthritis.
Rheumatology (Oxford, England) 1999;38 Suppl 2():3-7.
1999: Williams R O; Malfait A M; Butler D M; Walmsley M J; Feldmann M; Maini R N
Combination therapy with DMARDs and biological agents in collagen-induced arthritis.
Clinical and experimental rheumatology 1999;17(6 Suppl 18):S115-20.
1999: Maini R N; Taylor P C; Paleolog E; Charles P; Ballara S; Brennan F M; Feldmann M
Anti-tumour necrosis factor specific antibody (infliximab) treatment provides insights into the pathophysiology of rheumatoid arthritis.
Annals of the rheumatic diseases 1999;58 Suppl 1():I56-60.
1999: Feldmann M; Bondeson J; Brennan F M; Foxwell B M; Maini R N
The rationale for the current boom in anti-TNFalpha treatment. Is there an effective means to define therapeutic targets for drugs that provide all the benefits of anti-TNFalpha and minimise hazards?
Annals of the rheumatic diseases 1999;58 Suppl 1():I27-31.
1999: Charles P; Elliott M J; Davis D; Potter A; Kalden J R; Antoni C; Breedveld F C; Smolen J S; Eberl G; deWoody K; Feldmann M; Maini R N
Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(3):1521-8.
1999: Malfait A M; Malik A S; Marinova-Mutafchieva L; Butler D M; Maini R N; Feldmann M
The beta2-adrenergic agonist salbutamol is a potent suppressor of established collagen-induced arthritis: mechanisms of action.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(10):6278-83.
1999: Ballara S C; Siraj Q H; Maini R N; Venables P J
Sustained response to doxycycline therapy in two patients with SAPHO syndrome.
Arthritis and rheumatism 1999;42(4):819-21.
1999: Tan E M; Smolen J S; McDougal J S; Butcher B T; Conn D; Dawkins R; Fritzler M J; Gordon T; Hardin J A; Kalden J R; Lahita R G; Maini R N; Rothfield N F; Smeenk R; Takasaki Y; van Venrooij W J; Wiik A; Wilson M; Koziol J A
A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specificities. I. Precision, sensitivity, and specificity.
Arthritis and rheumatism 1999;42(3):455-64.
1998: Williams R O; Mauri C; Mason L J; Marinova-Mutafchieva L; Ross S E; Feldmann M; Maini R N
Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy.
Arthritis and rheumatism 1998;41(10):1806-12.
1998: Maini R N; Breedveld F C; Kalden J R; Smolen J S; Davis D; Macfarlane J D; Antoni C; Leeb B; Elliott M J; Woody J N; Schaible T F; Feldmann M
Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis.
Arthritis and rheumatism 1998;41(9):1552-63.
1998: Moyes S P; Maini R N; Mageed R A
Differential use of immunoglobulin light chain genes and B lymphocyte expansion at sites of disease in rheumatoid arthritis (RA) compared with circulating B lymphocytes.
Clinical and experimental immunology 1998;113(2):276-88.
1998: Paleolog E M; Young S; Stark A C; McCloskey R V; Feldmann M; Maini R N
Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor alpha and interleukin-1 in rheumatoid arthritis.
Arthritis and rheumatism 1998;41(7):1258-65.
1998: Malfait A M; Butler D M; Presky D H; Maini R N; Brennan F M; Feldmann M
Blockade of IL-12 during the induction of collagen-induced arthritis (CIA) markedly attenuates the severity of the arthritis.
Clinical and experimental immunology 1998;111(2):377-83.
1998: Feldmann M; Charles P; Taylor P; Maini R N
Biological insights from clinical trials with anti-TNF therapy.
Springer seminars in immunopathology 1998;20(1-2):211-28.
1998: Brennan F M; Maini R N; Feldmann M
Role of pro-inflammatory cytokines in rheumatoid arthritis.
Springer seminars in immunopathology 1998;20(1-2):133-47.
1998: Feldmann M; Maini R N
Rheumatoid arthritis: introduction.
Springer seminars in immunopathology 1998;20(1-2):3-4.
1997: Ross S E; Williams R O; Mason L J; Mauri C; Marinova-Mutafchieva L; Malfait A M; Maini R N; Feldmann M
Suppression of TNF-alpha expression, inhibition of Th1 activity, and amelioration of collagen-induced arthritis by rolipram.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):6253-9.
1997: Horsfall A C; Butler D M; Marinova L; Warden P J; Williams R O; Maini R N; Feldmann M
Suppression of collagen-induced arthritis by continuous administration of IL-4.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5687-96.
1997: Davis D; Charles P J; Potter A; Feldmann M; Maini R N; Elliott M J
Anaemia of chronic disease in rheumatoid arthritis: in vivo effects of tumour necrosis factor alpha blockade.
British journal of rheumatology 1997;36(9):950-6.
1997: Tan E M; Feltkamp T E; Smolen J S; Butcher B; Dawkins R; Fritzler M J; Gordon T; Hardin J A; Kalden J R; Lahita R G; Maini R N; McDougal J S; Rothfield N F; Smeenk R J; Takasaki Y; Wiik A; Wilson M R; Koziol J A
Range of antinuclear antibodies in "healthy" individuals.
Arthritis and rheumatism 1997;40(9):1601-11.
1997: Butler D M; Malfait A M; Mason L J; Warden P J; Kollias G; Maini R N; Feldmann M; Brennan F M
DBA/1 mice expressing the human TNF-alpha transgene develop a severe, erosive arthritis: characterization of the cytokine cascade and cellular composition.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(6):2867-76.
1997: Brennan F M; Browne K A; Green P A; Jaspar J M; Maini R N; Feldmann M
Reduction of serum matrix metalloproteinase 1 and matrix metalloproteinase 3 in rheumatoid arthritis patients following anti-tumour necrosis factor-alpha (cA2) therapy.
British journal of rheumatology 1997;36(6):643-50.
1997: Elliott M J; Woo P; Charles P; Long-Fox A; Woody J N; Maini R N
Suppression of fever and the acute-phase response in a patient with juvenile chronic arthritis treated with monoclonal antibody to tumour necrosis factor-alpha (cA2).
British journal of rheumatology 1997;36(5):589-93.
1997: Vencovský J; Maini R N; Ollier W E; Mageed R A
Immunoglobulin variable region (IgV) gene expression in rheumatoid factors from monozygotic twins with rheumatoid arthritis.
Annals of the New York Academy of Sciences 1997;815():324-6.
1997: Mageed R A; Moyes S P; Vencovský J; Maini R N
Somatic mutation and CDR3 length of immunoglobulin lambda variable region genes in the synovium of patients with rheumatoid arthritis.
Annals of the New York Academy of Sciences 1997;815():319-23.
1997: Maini R N; Elliott M; Brennan F M; Williams R O; Feldmann M
TNF blockade in rheumatoid arthritis: implications for therapy and pathogenesis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1997;105(4):257-63.
1997: Smolen J S; Butcher B; Fritzler M J; Gordon T; Hardin J; Kalden J R; Lahita R; Maini R N; Reeves W; Reichlin M; Rothfield N; Takasaki Y; van Venrooij W J; Tan E M
Reference sera for antinuclear antibodies. II. Further definition of antibody specificities in international antinuclear antibody reference sera by immunofluorescence and western blotting.
Arthritis and rheumatism 1997;40(3):413-8.
1997: Marinova-Mutafchieva L; Williams R O; Mason L J; Mauri C; Feldmann M; Maini R N
Dynamics of proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis (CIA).
Clinical and experimental immunology 1997;107(3):507-12.
1997: Feldmann M; Elliott M J; Woody J N; Maini R N
Anti-tumor necrosis factor-alpha therapy of rheumatoid arthritis.
Advances in immunology 1997;64():283-350.
1996: Horsfall A C; Li J M; Maini R N
Placental and fetal cardiac laminin are targets for cross-reacting autoantibodies from mothers of children with congenital heart block.
Journal of autoimmunity 1996;9(4):561-8.
1996: Maini R N
The role of cytokines in rheumatoid arthritis. The Croonian Lecture 1995.
Journal of the Royal College of Physicians of London 1996;30(4):344-51.
1996: Moyes S P; Brown C M; Scott B B; Maini R N; Mageed R A
Analysis of V kappa genes in rheumatoid arthritis (RA) synovial B lymphocytes provides evidence for both polyclonal activation and antigen-driven selection.
Clinical and experimental immunology 1996;105(1):89-98.
1996: Paleolog E M; Hunt M; Elliott M J; Feldmann M; Maini R N; Woody J N
Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor alpha antibody in rheumatoid arthritis.
Arthritis and rheumatism 1996;39(7):1082-91.
1996: Taylor P C; Chu C Q; Plater-Zyberk C; Maini R N
Transfer of type II collagen-induced arthritis from DBA/1 to severe combined immunodeficiency mice can be prevented by blockade of Mac-1.
Immunology 1996;88(2):315-21.
1996: Williams L M; Gibbons D L; Gearing A; Maini R N; Feldmann M; Brennan F M
Paradoxical effects of a synthetic metalloproteinase inhibitor that blocks both p55 and p75 TNF receptor shedding and TNF alpha processing in RA synovial membrane cell cultures.
The Journal of clinical investigation 1996;97(12):2833-41.
1996: Walmsley M; Katsikis P D; Abney E; Parry S; Williams R O; Maini R N; Feldmann M
Interleukin-10 inhibition of the progression of established collagen-induced arthritis.
Arthritis and rheumatism 1996;39(3):495-503.
1996: Brookes S M; Cohen S B; Price E J; Webb L M; Feldmann M; Maini R N; Venables P J
T cell clones from a Sjögren's syndrome salivary gland biopsy produce high levels of IL-10.
Clinical and experimental immunology 1996;103(2):268-72.
1995: Elliott M J; Maini R N
Anti-cytokine therapy in rheumatoid arthritis.
Baillière's clinical rheumatology 1995;9(4):633-52.
1995: Maini R N
A perspective on anti-cytokine and anti-T cell-directed therapies in rheumatoid arthritis.
Clinical and experimental rheumatology 1995;13 Suppl 12():S35-40.
1995: Misra R; Darton K; Jewkes R F; Black C M; Maini R N
Arthritis in scleroderma.
British journal of rheumatology 1995;34(9):831-7.
1995: Feldmann M; Brennan F M; Elliott M J; Williams R O; Maini R N
TNF alpha is an effective therapeutic target for rheumatoid arthritis.
Annals of the New York Academy of Sciences 1995;766():272-8.
1995: Maini R N; Elliott M J; Brennan F M; Feldmann M
Beneficial effects of tumour necrosis factor-alpha (TNF-alpha) blockade in rheumatoid arthritis (RA)
Clinical and experimental immunology 1995;101(2):207-12.
1995: Butler D M; Maini R N; Feldmann M; Brennan F M
Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonist.
European cytokine network 1995;6(4):225-30.
1995: Brennan F M; Gibbons D L; Cope A P; Katsikis P; Maini R N; Feldmann M
TNF inhibitors are produced spontaneously by rheumatoid and osteoarthritic synovial joint cell cultures: evidence of feedback control of TNF action.
Scandinavian journal of immunology 1995;42(1):158-65.
1995: Vencovsky J; Mageed R A; Ollier W E; Maini R N
Monozygotic rheumatoid arthritis twin pairs express similar levels of conserved immunoglobulin V gene in polyclonal rheumatoid factors irrespective of disease status.
Scandinavian journal of immunology 1995;42(1):147-57.
1995: Cohen S B; Katsikis P D; Chu C Q; Thomssen H; Webb L M; Maini R N; Londei M; Feldmann M
High level of interleukin-10 production by the activated T cell population within the rheumatoid synovial membrane.
Arthritis and rheumatism 1995;38(7):946-52.
1995: Maini R N; Elliott M J; Brennan F M; Williams R O; Chu C Q; Paleolog E; Charles P J; Taylor P C; Feldmann M
Monoclonal anti-TNF alpha antibody as a probe of pathogenesis and therapy of rheumatoid disease.
Immunological reviews 1995;144():195-223.
1995: Williams R O; Ghrayeb J; Feldmann M; Maini R N
Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD4.
Immunology 1995;84(3):433-9.
1995: Brown C M; Fitzgerald K J; Moyes S P; Mageed R A; Williams D G; Maini R N
Sequence analysis of immunoglobulin heavy-chain variable region genes from the synovium of a rheumatoid arthritis patient shows little evidence of mutation but diverse CDR3.
Immunology 1995;84(3):367-74.
1995: Brookes S M; Price E J; Venables P J; Maini R N
Interferon-gamma and epithelial cell activation in Sjögren's syndrome.
British journal of rheumatology 1995;34(3):226-31.
1995: Taylor P C; Plater-Zyberk C; Maini R N
The role of the B cells in the adoptive transfer of collagen-induced arthritis from DBA/1 (H-2q) to SCID (H-2d) mice.
European journal of immunology 1995;25(3):763-9.
1995: Elliott M J; Feldmann M; Maini R N
TNF alpha blockade in rheumatoid arthritis: rationale, clinical outcomes and mechanisms of action.
International journal of immunopharmacology 1995;17(2):141-5.
1995: Brennan F M; Cope A P; Katsikis P; Gibbons D L; Maini R N; Feldmann M
Selective immunosuppression of tumour necrosis factor-alpha in rheumatoid arthritis.
Chemical immunology 1995;60():48-60.
1994: Plater-Zyberk C; Taylor P C; Blaylock M G; Maini R N
Anti-CD5 therapy decreases severity of established disease in collagen type II-induced arthritis in DBA/1 mice.
Clinical and experimental immunology 1994;98(3):442-7.
1994: Maini R N; Elliott M; Brennan F M; Williams R O; Feldmann M
Targeting TNF alpha for the therapy of rheumatoid arthritis.
Clinical and experimental rheumatology 1994;12 Suppl 11():S63-6.
1994: Elliott M J; Maini R N; Feldmann M; Long-Fox A; Charles P; Bijl H; Woody J N
Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis.
Lancet 1994;344(8930):1125-7.
1994: Elliott M J; Maini R N; Feldmann M; Kalden J R; Antoni C; Smolen J S; Leeb B; Breedveld F C; Macfarlane J D; Bijl H
Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis.
Lancet 1994;344(8930):1105-10.
1994: Cope A P; Londei M; Chu N R; Cohen S B; Elliott M J; Brennan F M; Maini R N; Feldmann M
Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis.
The Journal of clinical investigation 1994;94(2):749-60.
1994: Scott B B; Sadigh S; Andrew E M; Maini R N; Mageed R A
Affinity maturation and isotype switch in clonally related anti-erythrocyte autoantibodies.
Scandinavian journal of immunology 1994;40(1):16-21.
1994: Katsikis P D; Chu C Q; Brennan F M; Maini R N; Feldmann M
Immunoregulatory role of interleukin 10 in rheumatoid arthritis.
The Journal of experimental medicine 1994;179(5):1517-27.
1994: Sadigh S; Scott B B; Mageed R A; Malcolm A; Andrew E M; Maini R N
Identification of hybridomas derived from mouse CD5+ B lymphocytes by fluorescent staining for cytoplasmic CD5 expression.
Immunology 1994;81(4):558-63.
1994: Williams R O; Mason L J; Feldmann M; Maini R N
Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2762-6.
1994: Mageed R A; Vencovsky J; Maini R N
Rheumatoid factors and germline genes in rheumatoid arthritis: evidence of an intrinsic B-lymphocyte defect?
British journal of rheumatology 1994;33(2):105-7.
1994: Maini R N; Elliott M J; Charles P J; Feldmann M
Immunological intervention reveals reciprocal roles for tumor necrosis factor-alpha and interleukin-10 in rheumatoid arthritis and systemic lupus erythematosus.
Springer seminars in immunopathology 1994;16(2-3):327-36.
1993: Elliott M J; Maini R N; Feldmann M; Long-Fox A; Charles P; Katsikis P; Brennan F M; Walker J; Bijl H; Ghrayeb J
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.
Arthritis and rheumatism 1993;36(12):1681-90.
1993: Charles P J; Maini R N
The clinical implications of autoantibody detection in rheumatology.
Journal of the Royal College of Physicians of London 1993;27(4):358-62.
1993: Aderka D; Wysenbeek A; Engelmann H; Cope A P; Brennan F; Molad Y; Hornik V; Levo Y; Maini R N; Feldmann M
Correlation between serum levels of soluble tumor necrosis factor receptor and disease activity in systemic lupus erythematosus.
Arthritis and rheumatism 1993;36(8):1111-20.
1993: Scott B B; Sadigh S; Stow M; Mageed R A; Andrew E M; Maini R N
Anti-mouse red blood cell monoclonal antibodies use functionally rearranged genes from the VH J558 family and are derived from the CD5- B-lymphocyte subpopulation.
Immunology 1993;79(4):568-73.
1993: Pease C T; Shattles W; Barrett N K; Maini R N
The arthropathy of Sjögren's syndrome.
British journal of rheumatology 1993;32(7):609-13.
1993: Pease C T; Charles P J; Shattles W; Markwick J; Maini R N
Serological and immunogenetic markers of extraglandular primary Sjögren's syndrome.
British journal of rheumatology 1993;32(7):574-7.
1993: Scott B B; Sadigh S; Stow M; Mageed R A; Andrew E M; Maini R N
Molecular mechanisms resulting in pathogenic anti-mouse erythrocyte antibodies in New Zealand black mice.
Clinical and experimental immunology 1993;93(1):26-33.
1993: Cope A P; Gibbons D L; Aderka D; Foxwell B M; Wallach D; Maini R N; Feldmann M; Brennan F M
Differential regulation of tumour necrosis factor receptors (TNF-R) by IL-4; upregulation of P55 and P75 TNF-R on synovial joint mononuclear cells.
Cytokine 1993;5(3):205-12.
1993: Maini R N; Brennan F M; Williams R; Chu C Q; Cope A P; Gibbons D; Elliott M; Feldmann M
TNF-alpha in rheumatoid arthritis and prospects of anti-TNF therapy.
Clinical and experimental rheumatology 1993;11 Suppl 8():S173-5.
1993: Charles P J; Maini R N
Antibodies to neutrophil cytoplasmic antigens in rheumatoid arthritis.
Advances in experimental medicine and biology 1993;336():367-70.
1992: Vencovsky J; Williams D G; Field M; Maini R N
Clinical associations of IgG antibodies to the ribonucleoprotein p67 polypeptide in patients with systemic lupus erythematosus.
Annals of the rheumatic diseases 1992;51(12):1313-7.
1992: Chu C Q; Field M; Andrew E; Haskard D; Feldmann M; Maini R N
Detection of cytokines at the site of tuberculin-induced delayed-type hypersensitivity in man.
Clinical and experimental immunology 1992;90(3):522-9.
1992: Deleuran B W; Chu C Q; Field M; Brennan F M; Katsikis P; Feldmann M; Maini R N
Localization of interleukin-1 alpha, type 1 interleukin-1 receptor and interleukin-1 receptor antagonist in the synovial membrane and cartilage/pannus junction in rheumatoid arthritis.
British journal of rheumatology 1992;31(12):801-9.
1992: Brookes S M; Pandolfino Y A; Mitchell T J; Venables P J; Shattles W G; Clark D A; Entwistle A; Maini R N
The immune response to and expression of cross-reactive retroviral gag sequences in autoimmune disease.
British journal of rheumatology 1992;31(11):735-42.
1992: Chu C Q; Field M; Allard S; Abney E; Feldmann M; Maini R N
Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: implications for the role of cytokines in cartilage destruction and repair.
British journal of rheumatology 1992;31(10):653-61.
1992: Deleuran B W; Chu C Q; Field M; Brennan F M; Mitchell T; Feldmann M; Maini R N
Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha.
Arthritis and rheumatism 1992;35(10):1170-8.
1992: Cope A P; Aderka D; Doherty M; Engelmann H; Gibbons D; Jones A C; Brennan F M; Maini R N; Wallach D; Feldmann M
Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases.
Arthritis and rheumatism 1992;35(10):1160-9.
1992: Brown C M; Longhurst C; Haynes G; Plater-Zyberk C; Malcolm A; Maini R N
Immunoglobulin heavy chain variable region gene utilization by B cell hybridomas derived from rheumatoid synovial tissue.
Clinical and experimental immunology 1992;89(2):230-8.
1992: Shattles W G; Brookes S M; Venables P J; Clark D A; Maini R N
Expression of antigen reactive with a monoclonal antibody to HTLV-1 P19 in salivary glands in Sjögren's syndrome.
Clinical and experimental immunology 1992;89(1):46-51.
1992: Brennan F M; Gibbons D L; Mitchell T; Cope A P; Maini R N; Feldmann M
Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints.
European journal of immunology 1992;22(7):1907-12.
1992: Cope A P; Jones A; Brozovic M; Shafi M S; Maini R N
Possible induction of systemic lupus erythematosus by human parvovirus.
Annals of the rheumatic diseases 1992;51(6):803-4.
1992: Williams R O; Plater-Zyberk C; Williams D G; Maini R N
Successful transfer of collagen-induced arthritis to severe combined immunodeficient (SCID) mice.
Clinical and experimental immunology 1992;88(3):455-60.
1992: Brennan F M; Maini R N; Feldmann M
TNF alpha--a pivotal role in rheumatoid arthritis?
British journal of rheumatology 1992;31(5):293-8.
1992: Plater-Zyberk C; Brown C M; Andrew E M; Maini R N
CD5+B in rheumatoid arthritis.
Annals of the New York Academy of Sciences 1992;651():540-50.
1992: Zheng R Q; Abney E R; Chu C Q; Field M; Maini R N; Lamb J R; Feldmann M
Detection of in vivo production of tumour necrosis factor-alpha by human thyroid epithelial cells.
Immunology 1992;75(3):456-62.
1992: Williams R O; Williams D G; Maini R N
Anti-type II collagen ELISA. Increased disease specificity following removal of anionic contaminants from salt-fractionated type II collagen.
Journal of immunological methods 1992;147(1):93-100.
1992: Feldmann M; Brennan F M; Williams R O; Cope A P; Gibbons D L; Katsikis P D; Maini R N
Evaluation of the role of cytokines in autoimmune disease: the importance of TNF alpha in rheumatoid arthritis.
Progress in growth factor research 1992;4(3):247-55.
1991: Chu C Q; Field M; Abney E; Zheng R Q; Allard S; Feldmann M; Maini R N
Transforming growth factor-beta 1 in rheumatoid synovial membrane and cartilage/pannus junction.
Clinical and experimental immunology 1991;86(3):380-6.
1991: Baboonian C; Venables P J; Williams D G; Williams R O; Maini R N
Cross reaction of antibodies to a glycine/alanine repeat sequence of Epstein-Barr virus nuclear antigen-1 with collagen, cytokeratin, and actin.
Annals of the rheumatic diseases 1991;50(11):772-5.
1991: Haworth C; Brennan F M; Chantry D; Turner M; Maini R N; Feldmann M
Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alpha.
European journal of immunology 1991;21(10):2575-9.
1991: Charles P J; Markwick J R; Venables P J; Maini R N
The association between HLA-DR3 and antibodies to the nuclear ribonucleoprotein La: differences between patients from northern Europe and those from the Indian subcontinent.
Disease markers 1991;9(5):297-9.
1991: Allard S A; Muirden K D; Maini R N
Correlation of histopathological features of pannus with patterns of damage in different joints in rheumatoid arthritis.
Annals of the rheumatic diseases 1991;50(5):278-83.
1991: Charles P J; Sweatman M C; Markwick J R; Maini R N
HLA-B40: a marker for susceptibility to lung disease in rheumatoid arthritis.
Disease markers 1991;9(2):97-101.
1991: Horsfall A C; Venables P J; Taylor P V; Maini R N
Ro and La antigens and maternal anti-La idiotype on the surface of myocardial fibres in congenital heart block.
Journal of autoimmunity 1991;4(1):165-76.
1991: Stocks M R; Williams D G; Maini R N
Analysis of a positive feedback mechanism in the anti-Sm autoantibody response of MRL/MPJ-lpr/lpr mice.
European journal of immunology 1991;21(2):267-72.
1991: Zheng R Q; Abney E; Chu C Q; Field M; Grubeck-Loebenstein B; Maini R N; Feldmann M
Detection of interleukin-6 and interleukin-1 production in human thyroid epithelial cells by non-radioactive in situ hybridization and immunohistochemical methods.
Clinical and experimental immunology 1991;83(2):314-9.
1991: Brennan F M; Field M; Chu C Q; Feldmann M; Maini R N
Cytokine expression in rheumatoid arthritis.
British journal of rheumatology 1991;30 Suppl 1():76-80.
1991: Venables P J; Williams D G; Horsfall A C; Williams R O; Stocks M R; Maini R N
The immune response to autoantigens and viruses in rheumatic disease.
British journal of rheumatology 1991;30 Suppl 1():70-4.
1991: Andrew E M; Plater-Zyberk C; Brown C M; Williams D G; Maini R N
The potential role of B-lymphocytes in the pathogenesis of rheumatoid arthritis.
British journal of rheumatology 1991;30 Suppl 1():47-52.
1990: Zheng R Q; Abney E R; Grubeck-Loebenstein B; Dayan C; Maini R N; Feldmann M
Expression of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-3 on human thyroid epithelial cells in Graves' and Hashimoto's diseases.
Journal of autoimmunity 1990;3(6):727-36.
1990: Baboonian C; Venables P J; Maini R N; Kangro H O; Osman H K
Antibodies to human herpesvirus-6 in Sjögren's syndrome.
Arthritis and rheumatism 1990;33(11):1749-50.
1990: Sethi D; Morgan T C; Brown E A; Cary N R; Erhardt C C; Pazianas M; Maini R N; Woodrow D F; Gower P E
Dialysis arthropathy: a clinical, biochemical, radiological and histological study of 36 patients.
The Quarterly journal of medicine 1990;77(282):1061-82.
1990: Brennan F M; Zachariae C O; Chantry D; Larsen C G; Turner M; Maini R N; Matsushima K; Feldmann M
Detection of interleukin 8 biological activity in synovial fluids from patients with rheumatoid arthritis and production of interleukin 8 mRNA by isolated synovial cells.
European journal of immunology 1990;20(9):2141-4.
1990: Maini R N; Plater-Zyberk C; Brown C M; Aghamohammadi S; Brennan F M; Feldmann M
CD5+B cells in rheumatoid arthritis and Sjögren's syndrome.
Clinical and experimental rheumatology 1990;8 Suppl 5():67-8.
1990: Brown C M; Plater-Zyberk C; Mageed R A; Jefferis R; Maini R N
Analysis of immunoglobulins secreted by hybridomas derived from rheumatoid synovia.
Clinical and experimental immunology 1990;80(3):366-72.
1990: Barkley D E; Feldmann M; Maini R N
Cells with dendritic morphology and bright interleukin-1 alpha staining circulate in the blood of patients with rheumatoid arthritis.
Clinical and experimental immunology 1990;80(1):25-31.
1990: Andrew E M; Annis W; Kahan M; Maini R N
CD5 (Ly-1)-negative, conventional splenic B cells make a substantial contribution to the bromelain plaque-forming cell response in CBA and BW mice.
Immunology 1990;69(4):515-8.
1990: Bijlsma J W; Plater-Zyberk C; Mumford P; Maini R N
Lack of natural antibodies in rheumatic diseases.
Rheumatology international 1990;10(3):107-12.
1989: Maini R N
Heberden Oration, 1988. Exploring immune pathways in rheumatoid arthritis.
British journal of rheumatology 1989;28(6):466-79.
1989: Field M; Melsom R D; Brennan F M; Williams D G; Schreiber L; McCarthy D A; Maini R N;
Rapid clearance of the lupus antigen Sm is delayed by autoantibody: a possible mechanism of autoimmunity perpetuation.
Clinical and experimental immunology 1989;78(3):460-4.
1989: Baboonian C; Venables P J; Booth J; Williams D G; Roffe L M; Maini R N
Virus infection induces redistribution and membrane localization of the nuclear antigen La (SS-B): a possible mechanism for autoimmunity.
Clinical and experimental immunology 1989;78(3):454-9.
1989: Horsfall A C; Rose L M; Maini R N
Autoantibody synthesis in salivary glands of Sjögren's syndrome patients.
Journal of autoimmunity 1989;2(4):559-68.
1989: Barkley D; Allard S; Feldmann M; Maini R N
Increased expression of HLA-DQ antigens by interstitial cells and endothelium in the synovial membrane of rheumatoid arthritis patients compared with reactive arthritis patients.
Arthritis and rheumatism 1989;32(8):955-63.
1989: Venables P J; Baboonian C; Horsfall A C; Halliday D; Maini R N; Teo C G; Mageed R; Millman G
The response to Epstein-Barr virus infection in Sjögren's syndrome.
Journal of autoimmunity 1989;2(4):439-48.
1989: Brennan F; Plater-Zyberk C; Maini R N; Feldmann M
Coordinate expansion of 'fetal type' lymphocytes (TCR gamma delta+T and CD5+B) in rheumatoid arthritis and primary Sjögren's syndrome.
Clinical and experimental immunology 1989;77(2):175-8.
1989: Brennan F M; Chantry D; Jackson A; Maini R; Feldmann M
Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis.
Lancet 1989;2(8657):244-7.
1989: Barkley D; Feldmann M; Maini R N
The detection by immunofluorescence of distinct cell populations producing interleukin-1 alpha and interleukin-1 beta in activated human peripheral blood.
Journal of immunological methods 1989;120(2):277-83.
1989: Venables P J; Baboonian C; Maini R N
Normal serologic response to Epstein-Barr virus in patients with Sjögren's syndrome.
Arthritis and rheumatism 1989;32(6):811-2.
1989: Brennan F M; Chantry D; Jackson A M; Maini R N; Feldmann M
Cytokine production in culture by cells isolated from the synovial membrane.
Journal of autoimmunity 1989;2 Suppl():177-86.
1989: Plater-Zyberk C; Brennan F M; Feldmann M; Maini R N
'Fetal-type' B and T lymphocytes in rheumatoid arthritis and primary Sjögren's syndrome.
Journal of autoimmunity 1989;2 Suppl():233-41.
1989: Hughes R A; Allard S A; Maini R N
Arthritis associated with adjuvant mycobacterial treatment for carcinoma of the bladder.
Annals of the rheumatic diseases 1989;48(5):432-4.
1989: Pease C T; Shattles W; Charles P J; Venables P J; Maini R N
Clinical, serological, and HLA phenotype subsets in Sjögren's syndrome.
Clinical and experimental rheumatology 1989;7(2):185-90.
1989: Venables P J; Shattles W; Pease C T; Ellis J E; Charles P J; Maini R N
Anti-La (SS-B): a diagnostic criterion for Sjögren's syndrome?
Clinical and experimental rheumatology 1989;7(2):181-4.
1989: Erhardt C C; Mumford P A; Venables P J; Maini R N
Factors predicting a poor life prognosis in rheumatoid arthritis: an eight year prospective study.
Annals of the rheumatic diseases 1989;48(1):7-13.
1989: Kissonerghis A M; Maini R N; Feldmann M
High rate of HLA class II mRNA synthesis in rheumatoid arthritis joints and its persistence in culture: down-regulation by recombinant interleukin 2.
Scandinavian journal of immunology 1989;29(1):73-82.
1989: Chantry D; Winearls C G; Maini R N; Feldmann M
Mechanism of immune complex-mediated damage: induction of interleukin 1 by immune complexes and synergy with interferon-gamma and tumor necrosis factor-alpha.
European journal of immunology 1989;19(1):189-92.
1989: Misra R; Venables P J; Plater-Zyberk C; Watkins P F; Maini R N
Anti-cardiolipin antibodies in infectious mononucleosis react with the membrane of activated lymphocytes.
Clinical and experimental immunology 1989;75(1):35-40.
1989: Londei M; Savill C M; Verhoef A; Brennan F; Leech Z A; Duance V; Maini R N; Feldmann M
Persistence of collagen type II-specific T-cell clones in the synovial membrane of a patient with rheumatoid arthritis.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(2):636-40.
1989: Baboonian C; Halliday D; Venables P J; Pawlowski T; Millman G; Maini R N
Antibodies in rheumatoid arthritis react specifically with the glycine alanine repeat sequence of Epstein-Barr nuclear antigen-1.
Rheumatology international 1989;9(3-5):161-6.
1988: Hirano T; Matsuda T; Turner M; Miyasaka N; Buchan G; Tang B; Sato K; Shimizu M; Maini R; Feldmann M
Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis.
European journal of immunology 1988;18(11):1797-801.
1988: Field M; Williams D G; Charles P; Maini R N
Specificity of anti-Sm antibodies by ELISA for systemic lupus erythematosus: increased sensitivity of detection using purified peptide antigens.
Annals of the rheumatic diseases 1988;47(10):820-5.
1988: Buchan G; Barrett K; Turner M; Chantry D; Maini R N; Feldmann M
Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha.
Clinical and experimental immunology 1988;73(3):449-55.
1988: Brennan F M; Allard S; Londei M; Savill C; Boylston A; Carrel S; Maini R N; Feldmann M
Heterogeneity of T cell receptor idiotypes in rheumatoid arthritis.
Clinical and experimental immunology 1988;73(3):417-23.
1988: Kennedy T D; Plater-Zyberk C; Partridge T A; Woodrow D F; Maini R N
Morphometric comparison of synovium from patients with osteoarthritis and rheumatoid arthritis.
Journal of clinical pathology 1988;41(8):847-52.
1988: Kennedy T D; Plater-Zyberk C; Partridge T A; Woodrow D F; Maini R N
Representative sample of rheumatoid synovium: a morphometric study.
Journal of clinical pathology 1988;41(8):841-6.
1988: Brennan F M; Londei M; Jackson A M; Hercend T; Brenner M B; Maini R N; Feldmann M
T cells expressing gamma delta chain receptors in rheumatoid arthritis.
Journal of autoimmunity 1988;1(4):319-26.
1988: Sethi D; Brown E A; Maini R N; Gower P E
Renal transplantation for dialysis arthropathy.
Lancet 1988;2(8608):448-9.
1988: Plater-Zyberk C; Rockett K A; Maini R N
Spontaneous recovery of the decreased expression in vitro of interleukin 2 receptors in rheumatoid arthritis.
Clinical and experimental immunology 1988;73(1):93-7.
1988: Feldmann M; Londei M; Grubeck-Loebenstein B; De Berardinis P; Leech Z; Turner M; Barrett K; Buchan G; Maini R N
Understanding what infiltrating cells do in autoimmunity: combination of cellular and molecular approaches.
Transplantation proceedings 1988;20(2):311-4.
1988: Venables P J; Pawlowski T; Mumford P A; Brown C; Crawford D H; Maini R N
Reaction of antibodies to rheumatoid arthritis nuclear antigen with a synthetic peptide corresponding to part of Epstein-Barr nuclear antigen 1.
Annals of the rheumatic diseases 1988;47(4):270-9.
1988: Brennan F M; Andrew E M; Williams D G; Maini R N
Anti-nRNP anti-nuclear antibody-secreting cells are represented in the B-lymphocyte repertoire of normal and MRL/MP-lpr/lpr lupus mice.
Immunology 1988;63(2):213-7.
1988: Buchan G; Barrett K; Fujita T; Taniguchi T; Maini R; Feldmann M
Detection of activated T cell products in the rheumatoid joint using cDNA probes to Interleukin-2 (IL-2) IL-2 receptor and IFN-gamma.
Clinical and experimental immunology 1988;71(2):295-301.
1988: Horsfall A C; Mumford P A; Venables P J; Maini R N
Anti-idiotypic induced suppression of Sjögren's syndrome associated anti-La autoantibody secretion in vitro.
Clinical and experimental immunology 1988;71(1):62-6.
1988: Venables P J; Rigby S; Mumford P A; Markwick J; Maini R N
Autoimmunity to La (SS-B) in vitro is related to HLA-DR3 in healthy subjects.
Annals of the rheumatic diseases 1988;47(1):22-7.
1988: Sethi D; Muller B R; Brown E A; Maini R N; Gower P E
C-reactive protein in haemodialysis patients with dialysis arthropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1988;3(3):269-71.
1988: Andrew E; Annis W; Maini R N
Both Ly-1 B cells and conventional B cells make autoantibodies to bromelain-treated autologous erythrocytes.
Advances in experimental medicine and biology 1988;237():119-23.
1988: Feldmann M; Kissonerghis A M; Buchan G; Brennan F; Turner M; Haworth C; Barrett K; Chantry D; Ziegler A; Maini R N
Role of HLA class II and cytokine expression in rheumatoid arthritis.
Scandinavian journal of rheumatology. Supplement 1988;76():39-46.
1988: Maini R N; Zyberk C P
The significance of CD5+ B cells in rheumatic diseases.
Scandinavian journal of rheumatology. Supplement 1988;76():237-42.
1988: Allard S A; Maini R N; Muirden K D
Cells and matrix expressing cartilage components in fibroblastic tissue in rheumatoid pannus.
Scandinavian journal of rheumatology. Supplement 1988;76():125-9.
1988: Horsfall A C; Venables P J; Allard S A; Maini R N
Co-existent anti-La antibodies and rheumatoid factors bear distinct idiotypic markers.
Scandinavian journal of rheumatology. Supplement 1988;75():84-8.
1988: Muirden K D; Allard S A; Rogers K; Maini R N
Immuno-electron microscopy of chondrocyte-derived cells in the rheumatoid cartilage-pannus junction.
Rheumatology international 1988;8(5):231-4.
1988: Feldmann M; Londei M; Leech Z; Brennan F; Savill C; Maini R N
Analysis of T cell clones in rheumatoid arthritis.
Springer seminars in immunopathology 1988;10(2-3):157-67.
1988: Plater-Zyberk C; Maini R N
Phenotypic and functional features of CD5+ B lymphocytes in rheumatoid arthritis.
Scandinavian journal of rheumatology. Supplement 1988;75():76-83.
1987: Horsfall A C; Brown C M; Maini R N
Purification of human autoantibodies from cross-linked antigen immunosorbents.
Journal of immunological methods 1987;104(1-2):43-9.
1987: Field M; Brennan F M; McCarthy D; Mumford P; Maini R N
MRL-lpr/lpr mice show an impairment of IgG aggregate removal which relates to parameters of disease activity.
Immunology 1987;61(4):463-7.
1987: Maini R N; Plater-Zyberk C; Andrew E
Autoimmunity in rheumatoid arthritis. An approach via a study of B lymphocytes.
Rheumatic diseases clinics of North America 1987;13(2):319-38.
1987: Allard S A; Muirden K D; Camplejohn K L; Maini R N
Chondrocyte-derived cells and matrix at the rheumatoid cartilage-pannus junction identified with monoclonal antibodies.
Rheumatology international 1987;7(4):153-9.
1986: Selmaj K; Plater-Zyberk C; Rockett K A; Maini R N; Alam R; Perkin G D; Rose F C
Multiple sclerosis: increased expression of interleukin-2 receptors on lymphocytes.
Neurology 1986;36(10):1392-5.
1986: Jaraquemada D; Ollier W; Awad J; Young A; Silman A; Roitt I M; Corbett M; Hay F; Cosh J A; Maini R N
HLA and rheumatoid arthritis: a combined analysis of 440 British patients.
Annals of the rheumatic diseases 1986;45(8):627-36.
1986: Sweatman M C; Markwick J R; Charles P J; Jones S E; Prior J M; Maini R N; Turner-Warwick M E
Histocompatibility antigens in adult obliterative bronchiolitis with or without rheumatoid arthritis.
Disease markers 1986;4(1-2):19-26.
1986: Horsfall A C; Venables P J; Mumford P A; Maini R N
Idiotypes on antibodies to the La (SS-B) antigen are restricted and associated with the antigen binding site.
Clinical and experimental immunology 1986;63(2):395-401.
1986: Melsom R D; Horsfall A C; Schrieber L; Charles P; Maini R N
Anti-C1q affinity isolated circulating immune complexes correlate with extra-articular rheumatoid disease.
Rheumatology international 1986;6(5):227-31.
1985: Venables P J; Ross M G; Charles P J; Melsom R D; Griffiths P D; Maini R N
A seroepidemiological study of cytomegalovirus and Epstein-Barr virus in rheumatoid arthritis and sicca syndrome.
Annals of the rheumatic diseases 1985;44(11):742-6.
1985: McCarthy D A; Field M; Mumford P; Pell B K; Holborow E J; Maini R N
The production of small IgG aggregates by glutaraldehyde cross-linking.
Journal of immunological methods 1985;82(2):349-58.
1985: McCarthy D A; Field M; Mumford P; Moore S R; Holborow E J; Maini R N
Soluble IgG aggregates produced by heating remain stable on freeze-drying.
Journal of immunological methods 1985;82(1):155-60.
1985: Plater-Zyberk C; Maini R N; Lam K; Kennedy T D; Janossy G
A rheumatoid arthritis B cell subset expresses a phenotype similar to that in chronic lymphocytic leukemia.
Arthritis and rheumatism 1985;28(9):971-6.
1985: Field M; Brennan F M; Melsom R D; McCarthy D; Mumford P; Maini R N
MRL mice show an age-related impairment of IgG aggregate removal from the circulation.
Clinical and experimental immunology 1985;61(1):195-202.
1985: Plater-Zyberk C; Lam K; Kennedy T D; Maini R N; Janossy G
Increased representation of a subpopulation of early B cells in the peripheral blood of patients with rheumatoid arthritis.
Advances in experimental medicine and biology 1985;186():957-61.
1985: Mumford P; Room G R; Venables P J; Maini R N
IgG antibodies to SS-B (La), RNP/Sm and DNA are produced by PWM-stimulated normal human lymphocytes in culture.
Rheumatology international 1985;5(3):109-12.
1985: Maini R N; Charles P J; Venables P J
Antinuclear antibodies in the immunotaxonomy of connective tissue diseases.
Scandinavian journal of rheumatology. Supplement 1985;56():49-57.
1984: Ollier W; Venables P J; Mumford P A; Maini R N; Awad J; Jaraquemada D; D'Amaro J; Festenstein H
HLA antigen associations with extra-articular rheumatoid arthritis.
Tissue antigens 1984;24(5):279-91.
1984: Chapman J R; Charles P J; Venables P J; Thompson P J; Haslam P L; Maini R N; Turner Warwick M E
Definition and clinical relevance of antibodies to nuclear ribonucleoprotein and other nuclear antigens in patients with cryptogenic fibrosing alveolitis.
The American review of respiratory disease 1984;130(3):439-43.
1984: Schrieber L; Melsom R D; Venables P J; McCarthy D A; Maini R N
Specific autoantibody slows the rapid plasma clearance of 125I-SS-B (La) in mice.
Clinical and experimental immunology 1984;56(3):621-7.
1984: Erhardt C C; Mumford P; Maini R N
Differences in immunochemical characteristics of cryoglobulins in rheumatoid arthritis and systemic lupus erythematosus and their complement binding properties.
Annals of the rheumatic diseases 1984;43(3):451-6.
1984: Schrieber L; Melsom R D; Venables P J; Maini R N
Tissue uptake and catabolic studies of 125I SS-B (La) injected into mice.
Clinical immunology and immunopathology 1984;31(1):24-32.
1983: Plater-Zyberk C; Clarke M F; Lam K; Mumford P A; Room G R; Maini R N
In vitro immunoglobulin synthesis by lymphocytes from patients with rheumatoid arthritis. I. Effect of monocyte depletion and demonstration of an increased proportion of lymphocytes forming rosettes with mouse erythrocytes.
Clinical and experimental immunology 1983;52(3):505-11.
1983: Schrieber L; Erhardt C C; Melsom R D; Venables P J; McCarthy D A; Mumford P A; Horsfall A C; Maini R N
In vivo fate of 125I SS-B (La) injected into mice.
Immunology 1983;48(4):771-8.
1983: Venables P J; Charles P J; Buchanan R R; Yi T; Mumford P A; Schrieber L; Room G R; Maini R N
Quantitation and detection of isotypes of anti-SS-B antibodies by ELISA and Farr assays using affinity purified antigens. An approach to the investigation of Sjögren's syndrome and systemic lupus erythematosus.
Arthritis and rheumatism 1983;26(2):146-55.
1983: Buchanan R R; Venables P J; Morgan A; Staines N A; Smith P R; Maini R N
Separation of two molecular species of the Sm antigen by affinity chromatography with murine monoclonal and human anti-nuclear autoantibodies.
Clinical and experimental immunology 1983;51(1):8-16.
1982: Room G R; Plater-Zyberk C; Clarke M F; Maini R N
B-lymphocyte subpopulation which forms rosettes with mouse erythrocytes increased in rheumatoid arthritis.
Rheumatology international 1982;2(4):175-8.
1981: Venables P J; Roffe L M; Erhardt C C; Maini R N; Edwards J M; Porter A D
Titers of antibodies to RANA in rheumatoid arthritis and normal sera. Relationship to Epstein-Barr virus infection.
Arthritis and rheumatism 1981;24(12):1459-68.
1981: Venables P J; Mumford P A; Maini R N
Antibodies to nuclear antigens in polymyositis: relationship to autoimmune 'overlap syndromes' and carcinoma.
Annals of the rheumatic diseases 1981;40(3):217-23.
1981: Horsfall A C; Venables P J; Mumford P A; Maini R N
Interpretation of the Raji cell assay in sera containing anti-nuclear antibodies and immune complexes.
Clinical and experimental immunology 1981;44(2):405-15.
1981: McCarthy D; Goddard D H; Holborow E J; Horsfall A C; Mumford P A; Maini R N
The effect of IgG aggregate size and concentration on reactivity in immune complex assays.
Journal of immunological methods 1981;47(3):349-58.
1980: Venables P J; Erhardt C C; Maini R N
Antibodies to extractable nuclear antigens in rheumatoid arthritis: relationship to vasculitis and circulating immune complexes.
Clinical and experimental immunology 1980;39(1):146-53.

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