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Shirish Barve

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Irina A Kirpich; Yanlong Liu; Yuhua Wang; Gavin E Arteel; Shirish Barve; Juliane I Beier; K Cameron Falkner; Wenke Feng; Craig J McClain
Ethanol and dietary unsaturated fat (corn oil/linoleic acid enriched) cause intestinal inflammation and impaired intestinal barrier defense in mice chronically fed alcohol.
Lara Bull-Otterson; Wenke Feng; Leila Gobejishvili; Swati Joshi-Barve; Irina Kirpich; Maiying Kong; Yanlong Liu; Craig McClain; Joseph F Petrosino; Xiang Qin; Yuhua Wang; Tulin Ayvaz; David Barker; Shirish Barve
Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment.
Kusum K Kharbanda; Patricia E Molina; Fawzia Bardag-Gorce; Shirish Barve; Natalia A Osna
Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases.

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2013: Irina A Kirpich; Yanlong Liu; Yuhua Wang; Gavin E Arteel; Shirish Barve; Juliane I Beier; K Cameron Falkner; Wenke Feng; Craig J McClain
Ethanol and dietary unsaturated fat (corn oil/linoleic acid enriched) cause intestinal inflammation and impaired intestinal barrier defense in mice chronically fed alcohol.
Alcohol (Fayetteville, N.Y.) 2013;47(3):257-64.
2013: Lara Bull-Otterson; Wenke Feng; Leila Gobejishvili; Swati Joshi-Barve; Irina Kirpich; Maiying Kong; Yanlong Liu; Craig McClain; Joseph F Petrosino; Xiang Qin; Yuhua Wang; Tulin Ayvaz; David Barker; Shirish Barve
Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment.
PloS one 2013;8(1):e53028.
2013: Kusum K Kharbanda; Patricia E Molina; Fawzia Bardag-Gorce; Shirish Barve; Natalia A Osna
Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases.
Alcoholism, clinical and experimental research 2013;37(1):1-7.
2012: Mohammad K Mohammad; Jingwen Zhang; Craig McClain; Gavin E Arteel; Diana Avila; Shirish Barve; Swati Joshi-Barve
Acrolein cytotoxicity in hepatocytes involves endoplasmic reticulum stress, mitochondrial dysfunction and oxidative stress.
Toxicology and applied pharmacology 2012;265(1):73-82.
2012: Irina Kirpich; Craig J McClain; Akshata Moghe; Jingwen Zhang; Swati Joshi Barve; Smita Ghare; Leila Gobejishvili; Giorgi Kharebava; David Barker; Shirish Barve
Binge alcohol-induced microvesicular liver steatosis and injury are associated with down-regulation of hepatic Hdac 1, 7, 9, 10, 11 and up-regulation of Hdac 3.
Alcoholism, clinical and experimental research 2012;36(9):1578-86.
2012: Irina A Kirpich; Yanlong Liu; David F Barker; Shirish Barve; Wenke Feng; Yuhua Wang; Craig J McClain
The type of dietary fat modulates intestinal tight junction integrity, gut permeability, and hepatic toll-like receptor expression in a mouse model of alcoholic liver disease.
Alcoholism, clinical and experimental research 2012;36(5):835-46.
2011: Yuhua Wang; Shirish Barve; Irina Kirpich; Yanlong Liu; Zhenhua Ma; Craig J McClain; Wenke Feng
Lactobacillus rhamnosus GG treatment potentiates intestinal hypoxia-inducible factor, promotes intestinal integrity and ameliorates alcohol-induced liver injury.
The American journal of pathology 2011;179(6):2866-75.
2011: Smita Ghare; Prachi Hote; Craig McClain; Madhuvanti Patil; Jill Suttles; Shirish Barve; Swati Joshi-Barve
Ethanol inhibits lipid raft-mediated TCR signaling and IL-2 expression: potential mechanism of alcohol-induced immune suppression.
Alcoholism, clinical and experimental research 2011;35(8):1435-44.
2011: Akshata Moghe; Swati Joshi-Barve; Smita Ghare; Leila Gobejishvili; Irina Kirpich; Craig J McClain; Shirish Barve
Histone modifications and alcohol-induced liver disease: are altered nutrients the missing link?
World journal of gastroenterology : WJG 2011;17(20):2465-72.
2011: Craig J McClain; Shirish Barve; Ashutosh Barve; Luis S Marsano
Alcoholic liver disease and malnutrition.
Alcoholism, clinical and experimental research 2011;35(5):815-20.
2011: Leila Gobejishvili; Diana V Avila; David Barker; Smita Ghare; David Henderson; Guy N Brock; Irina A Kirpich; Swati Joshi-Barve; Sri Prakash L Mokshagundam; Craig J McClain; Shirish Barve
S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway.
The Journal of pharmacology and experimental therapeutics 2011;337(2):433-43.
2011: Irina A Kirpich; Leila N Gobejishvili; Marjorie Bon Homme; Sabine Waigel; Matt Cave; Gavin Arteel; Shirish Barve; Craig J McClain; Ion V Deaciuc
Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease.
The Journal of nutritional biochemistry 2011;22(1):38-45.
2010: Shirish Barve; John W Eaton; Leila Gobejishvili; Swati Joshi-Barve; Rama Kapoor; Akshata Moghe; Julio A Ramirez; Craig J McClain
Focus on the Liver: Alcohol Use, Highly Active Antiretroviral Therapy, and Liver Disease in HIV-Infected Patients.
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 2010;33(3):229-36.
2009: Swati Joshi-Barve; Kiranmayi Amancherla; Madhuvanti Patil; Aruni Bhatnagar; Stephanie Mathews; Leila Gobejishvili; Matthew Cave; Craig McClain; Shirish Barve
Acrolein, a ubiquitous pollutant and lipid hydroperoxide product, inhibits antiviral activity of interferon-alpha: relevance to hepatitis C.
Free radical biology & medicine 2009;47(1):47-54.
2009: Tanvi S Jani; Leila Gobejishvili; Prachi T Hote; Aditya S Barve; Swati Joshi-Barve; Giorgi Kharebava; Jill Suttles; Theresa Chen; Craig J McClain; Shirish Barve
Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells.
Cell research 2009;19(3):358-69.
2008: Miriam B Vos; Shirish Barve; Swati Joshi-Barve; John D Carew; Peter F Whitington; Craig J McClain
Cytokeratin 18, a marker of cell death, is increased in children with suspected nonalcoholic fatty liver disease.
Journal of pediatric gastroenterology and nutrition 2008;47(4):481-5.
2008: Leila Gobejishvili; Shirish Barve; Swati Joshi-Barve; Craig McClain
Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(4):G718-24.
2008: Prachi T Hote; Rashmita Sahoo; Tanvi S Jani; Smita S Ghare; Theresa Chen; Swati Joshi-Barve; Craig J McClain; Shirish Barve
Ethanol inhibits methionine adenosyltransferase II activity and S-adenosylmethionine biosynthesis and enhances caspase-3-dependent cell death in T lymphocytes: relevance to alcohol-induced immunosuppression.
The Journal of nutritional biochemistry 2008;19(6):384-91.
2008: Ming Song; Zhenyuan Song; Shirish Barve; Jingwen Zhang; Theresa Chen; Marcia Liu; Gavin E Arteel; George J Brewer; Craig J McClain
Tetrathiomolybdate protects against bile duct ligation-induced cholestatic liver injury and fibrosis.
The Journal of pharmacology and experimental therapeutics 2008;325(2):409-16.
2008: Ion V Deaciuc; Zhenyuan Song; Xuejun Peng; Shirish Barve; Ming Song; Qiang He; Thomas B Knudsen; Amar Singh; Craig J McClain
Genome-wide transcriptome expression in the liver of a mouse model of high carbohydrate diet-induced liver steatosis and its significance for the disease.
Hepatology international 2008;2(1):39-49.
2008: Weiyuan Chang; Craig J McClain; Marcia C Liu; Shirish Barve; Theresa S Chen
Effects of 2(RS)-n-propylthiazolidine-4(R)-carboxylic acid on 4-hydroxy-2-nonenal-induced apoptotic T cell death.
The Journal of nutritional biochemistry 2008;19(3):184-92.
2007: Terrence M Donohue; Arthur I Cederbaum; Samuel W French; Shirish Barve; Bin Gao; Natalia A Osna
Role of the proteasome in ethanol-induced liver pathology.
Alcoholism, clinical and experimental research 2007;31(9):1446-59.
2007: Swati Joshi-Barve; Shirish Barve; Kiranmayi Amancherla; Leila Gobejishvili; Daniell Hill; Matthew Cave; Prachi Hote; Craig J McClain
Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes.
Hepatology (Baltimore, Md.) 2007;46(3):823-30.
2007: Vishnudutt Purohit; Manal F Abdelmalek; Shirish Barve; Norlin J Benevenga; Charles H Halsted; Neil Kaplowitz; Kusum K Kharbanda; Qi-Ying Liu; Shelly C Lu; Craig J McClain; Christine Swanson; Samir Zakhari
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
The American journal of clinical nutrition 2007;86(1):14-24.
2007: Craig J McClain; Shirish Barve; Ion V Deaciuc
Good fat/bad fat.
Hepatology (Baltimore, Md.) 2007;45(6):1343-6.
2007: Matthew Cave; Ion V Deaciuc; Christian Mendez; Zhenyuan Song; Swati Joshi-Barve; Shirish Barve; Craig McClain
Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition.
The Journal of nutritional biochemistry 2007;18(3):184-95.
2006: Shirish Barve; Swati Joshi-Barve; Zhenyuan Song; Daniell Hill; Prachi Hote; Ion V Deaciuc; Craig McClain
Interactions of cytokines, S-Adenosylmethionine, and S-Adenosylhomocysteine in alcohol-induced liver disease and immune suppression.
Journal of gastroenterology and hepatology 2006;21 Suppl 3():S38-42.
2006: Leila Gobejishvili; Shirish Barve; Swati Joshi-Barve; Silvia Uriarte; Zhenyuan Song; Craig McClain
Chronic ethanol-mediated decrease in cAMP primes macrophages to enhanced LPS-inducible NF-kappaB activity and TNF expression: relevance to alcoholic liver disease.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(4):G681-8.
2006: Allicia C Girvan; Yun Teng; Lavona K Casson; Shelia D Thomas; Simone Jüliger; Mark W Ball; Klein Jon; William M Pierce; Shirish Barve; Paula J Bates
AGRO100 inhibits activation of nuclear factor-kappaB (NF-kappaB) by forming a complex with NF-kappaB essential modulator (NEMO) and nucleolin.
Molecular cancer therapeutics 2006;5(7):1790-9.
2006: Suzana Brozovic; Rashmita Sahoo; Shirish Barve; Hideki Shiba; Silvia Uriarte; Richard S Blumberg; Denis F Kinane
Porphyromonas gingivalis enhances FasL expression via up-regulation of NFkappaB-mediated gene transcription and induces apoptotic cell death in human gingival epithelial cells.
Microbiology (Reading, England) 2006;152(Pt 3):797-806.
2005: Miriam V Louthan; Shirish Barve; Craig J McClain; Swati Joshi-Barve
Decreased serum adiponectin: an early event in pediatric nonalcoholic fatty liver disease.
The Journal of pediatrics 2005;147(6):835-8.
2005: Craig McClain; Shirish Barve; Swati Joshi-Barve; Zhenyuan Song; Ion V Deaciuc; Theresa Chen; Daniell Hill
Dysregulated cytokine metabolism, altered hepatic methionine metabolism and proteasome dysfunction in alcoholic liver disease.
Alcoholism, clinical and experimental research 2005;29(11 Suppl):180S-8S.
2005: Zhenyuan Song; Silvia Uriarte; Rashmita Sahoo; Theresa Chen; Shirish Barve; Daniell Hill; Craig McClain
S-adenosylmethionine (SAMe) modulates interleukin-10 and interleukin-6, but not TNF, production via the adenosine (A2) receptor.
Biochimica et biophysica acta 2005;1743(3):205-13.
2005: Silvia Uriarte; Swati Joshi-Barve; Zhenyuan Song; Rashmita Sahoo; Leila Gobejishvili; Venkatakrishna R Jala; Haribabu Bodduluri; Craig McClain; Shirish Barve
Akt inhibition upregulates FasL, downregulates c-FLIPs and induces caspase-8-dependent cell death in Jurkat T lymphocytes.
Cell death and differentiation 2005;12(3):233-42.
2004: Zhenyuan Song; Theresa Chen; Ion V Deaciuc; Silvia Uriarte; Daniell Hill; Shirish Barve; Craig J McClain
Modulation of endotoxin stimulated interleukin-6 production in monocytes and Kupffer cells by S-adenosylmethionine (SAMe).
Cytokine 2004;28(6):214-23.
2004: Zhenyuan Song; Zhanxiang Zhou; Silvia Uriarte; Lipeng Wang; Y James Kang; Theresa Chen; Shirish Barve; Craig J McClain
S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease.
Hepatology (Baltimore, Md.) 2004;40(4):989-97.
2004: Craig J McClain; Zhenyuan Song; Shirish Barve; Daniell B Hill; Ion V Deaciuc
Recent advances in alcoholic liver disease. IV. Dysregulated cytokine metabolism in alcoholic liver disease.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(3):G497-502.
2004: Craig J McClain; Sri Prakash L Mokshagundam; Shirish Barve; Zhenyuan Song; Daniell B Hill; Theresa Chen; Ion V Deaciuc
Mechanisms of non-alcoholic steatohepatitis.
Alcohol (Fayetteville, N.Y.) 2004;34(1):67-79.
2004: Craig J McClain; Daniell B Hill; Shirish Barve
Infliximab and prednisolone: too much of a good thing?
Hepatology (Baltimore, Md.) 2004;39(6):1488-90.
2004: Yan Zhao; Swati Joshi-Barve; Shirish Barve; Linda H Chen
Eicosapentaenoic acid prevents LPS-induced TNF-alpha expression by preventing NF-kappaB activation.
Journal of the American College of Nutrition 2004;23(1):71-8.
2004: Zhenyuan Song; Swati Joshi-Barve; Shirish Barve; Craig J McClain
Advances in alcoholic liver disease.
Current gastroenterology reports 2004;6(1):71-6.
2003: Swati Joshi-Barve; Shirish Barve; Waseem Butt; Jon Klein; Craig J McClain
Inhibition of proteasome function leads to NF-kappaB-independent IL-8 expression in human hepatocytes.
Hepatology (Baltimore, Md.) 2003;38(5):1178-87.
2003: Zhenyuan Song; Zhanxiang Zhou; Theresa Chen; Daniell Hill; James Kang; Shirish Barve; Craig McClain
S-adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice small star, filled.
The Journal of nutritional biochemistry 2003;14(10):591-7.
2003: Zhenyuan Song; Shirish Barve; Theresa Chen; Wendy Nelson; Silvia Uriarte; Daniell Hill; Craig McClain
S-adenosylmethionine (AdoMet) modulates endotoxin stimulated interleukin-10 production in monocytes.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(6):G949-55.
2003: Luis S Marsano; Christian Mendez; Daniell Hill; Shirish Barve; Craig J McClain
Diagnosis and treatment of alcoholic liver disease and its complications.
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 2003;27(3):247-56.
2002: Craig J McClain; Marion McClain; Shirish Barve; Maria G Boosalis
Trace metals and the elderly.
Clinics in geriatric medicine 2002;18(4):801-18, vii-viii.
2002: Craig J McClain; Daniell B Hill; Zhenyuan Song; Rajender Chawla; WALTER WATSON; Theresa Chen; Shirish Barve
S-Adenosylmethionine, cytokines, and alcoholic liver disease.
Alcohol (Fayetteville, N.Y.) 2002;27(3):185-92.
2002: Shirish Barve; Sujata V Kelkar; Leila Gobejishvilli; Swati Joshi-Barve; Craig J McClain
Mechanisms of alcohol-mediated CD4+ T lymphocyte death: relevance to HIV and HCV pathogenesis.
Frontiers in bioscience : a journal and virtual library 2002;7():d1689-96.
2002: Craig J McClain; Daniell B Hill; Zhenyuan Song; Ion V Deaciuc; Shirish Barve
Monocyte activation in alcoholic liver disease.
Alcohol (Fayetteville, N.Y.) 2002;27(1):53-61.
2002: Sujata Kelkar; Qing Dong; Yinghua Xiao; Swati Joshi-Barve; Craig J McClain; Shirish Barve
Ethanol enhances activation-induced caspase-3 dependent cell death in T lymphocytes.
Alcoholism, clinical and experimental research 2002;26(3):363-70.
2001: John A Blanchard; Shirish Barve; Swati Joshi-Barve; R Talwalker; Lawrence K Gates
Antioxidants inhibit cytokine production and suppress NF-kappaB activation in CAPAN-1 and CAPAN-2 cell lines.
Digestive diseases and sciences 2001;46(12):2768-72.
2001: F Yang; Helieh S Oz; Shirish Barve; Willem J S de Villiers; Craig J McClain; Gary W Varilek
The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting I kappa B kinase activity in the intestinal epithelial cell line IEC-6.
Molecular pharmacology 2001;60(3):528-33.
2001: Terrence M Donohue; Dahn L Clemens; A Galli; D Crabb; N Nieto; J Kato; Shirish Barve
Use of cultured cells in assessing ethanol toxicity and ethanol-related metabolism.
Alcoholism, clinical and experimental research 2001;25(5 Suppl ISBRA):87S-93S.
2000: Q Dong; S Kelkar; Y Xiao; Swati Joshi-Barve; Craig J McClain; Shirish Barve
Ethanol enhances TNF-alpha-inducible NFkappaB activation and HIV-1-LTR transcription in CD4+ Jurkat T lymphocytes.
The Journal of laboratory and clinical medicine 2000;136(5):333-43.
2000: Daniell B Hill; Shirish Barve; Swati Joshi-Barve; Craig McClain
Increased monocyte nuclear factor-kappaB activation and tumor necrosis factor production in alcoholic hepatitis.
The Journal of laboratory and clinical medicine 2000;135(5):387-95.
2000: John A Blanchard; Shirish Barve; Swati Joshi-Barve; R Talwalker; Lawrence K Gates
Cytokine production by CAPAN-1 and CAPAN-2 cell lines.
Digestive diseases and sciences 2000;45(5):927-32.
1999: MN Devalaraja; Craig J McClain; Shirish Barve; K Vaddi; Daniell B Hill
Increased monocyte MCP-1 production in acute alcoholic hepatitis.
Cytokine 1999;11(11):875-81.
1999: Daniell B Hill; R Devalaraja; Swati Joshi-Barve; Shirish Barve; Craig J McClain
Antioxidants attenuate nuclear factor-kappa B activation and tumor necrosis factor-alpha production in alcoholic hepatitis patient monocytes and rat Kupffer cells, in vitro.
Clinical biochemistry 1999;32(7):563-70.
1999: Daohong Zhou; SA Brown; T Yu; G Chen; Shirish Barve; BC Kang; John S Thompson
A high dose of ionizing radiation induces tissue-specific activation of nuclear factor-kappaB in vivo.
Radiation research 1999;151(6):703-9.
1999: Craig J McClain; S Price; Shirish Barve; R Devalarja; Steven I Shedlofsky
Acetaminophen hepatotoxicity: An update.
Current gastroenterology reports 1999;1(1):42-9.
1999: Craig J McClain; Shirish Barve; Ion V Deaciuc; Marcelo Kugelmas; D Hill
Cytokines in alcoholic liver disease.
Seminars in liver disease 1999;19(2):205-19.
1998: Craig J McClain; Shirish Barve; S Barve; Ion V Deaciuc; Daniell B Hill
Tumor necrosis factor and alcoholic liver disease.
Alcoholism, clinical and experimental research 1998;22(5 Suppl):248S-252S.
1998: Daniell B Hill; Craig J McClain; D St Clair; Shirish Barve
Use of transfected liver cells to evaluate potential mechanisms of alcohol-induced liver injury.
Alcoholism, clinical and experimental research 1998;22(4):785-8.
1997: P Connell; V M Young; Michal J Toborek; D A Cohen; Shirish Barve; Craig J McClain; Bernhard Hennig
Zinc attenuates tumor necrosis factor-mediated activation of transcription factors in endothelial cells.
Journal of the American College of Nutrition 1997;16(5):411-7.
1997: Craig J McClain; Steven I Shedlofsky; Shirish Barve; Daniell B Hill
Cytokines and alcoholic liver disease.
Alcohol health and research world 1997;21(4):317-20.
1996: S A Brown; B A Lucas; Thomas Waid; John W McKeown; Shirish Barve; L R Jackson; J S Thompson
T10B9 (MEDI-500) mediated immunosuppression: studies on the mechanism of action.
Clinical transplantation 1996;10(6 Pt 2):607-13.
1996: Bernhard Hennig; Michal J Toborek; S Joshi-Barve; Steven W Barger; Shirish Barve; Mark P Mattson; Craig J McClain
Linoleic acid activates nuclear transcription factor-kappa B (NF-kappa B) and induces NF-kappa B-dependent transcription in cultured endothelial cells.
The American journal of clinical nutrition 1996;63(3):322-8.
1996: Michal J Toborek; Steven W Barger; Mark P Mattson; Shirish Barve; Craig J McClain; Bernhard Hennig
Linoleic acid and TNF-alpha cross-amplify oxidative injury and dysfunction of endothelial cells.
Journal of lipid research 1996;37(1):123-35.
1994: Shirish Barve; Donald A Cohen; Arrigo De Benedetti; Robert E Rhoads; Alan M Kaplan
Mechanism of differential regulation of IL-2 in murine Th1 and Th2 T cell subsets. 1. Induction of IL-2 transcription in Th2 cells by up-regulation of transcription factors with the protein synthesis initiation factor 4E.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(3):1171-81.
1993: Donald A Cohen; EA Fitzpatrick; Shirish Barve; Guthridge Joel; Robert J Jacob; L Simmerman; Alan M Kaplan
Activation-dependent apoptosis in CD4+ T cells during murine AIDS.
Cellular immunology 1993;151(2):392-403.
1991: Gregory V Plano; Shirish Barve; Susan C Straley
LcrD, a membrane-bound regulator of the Yersinia pestis low-calcium response.
Journal of bacteriology 1991;173(22):7293-303.
1990: Shirish Barve; Susan C Straley
lcrR, a low-Ca2(+)-response locus with dual Ca2(+)-dependent functions in Yersinia pestis.
Journal of bacteriology 1990;172(8):4661-71.
1989: S B Price; K Y Leung; Shirish Barve; Susan C Straley
Molecular analysis of lcrGVH, the V antigen operon of Yersinia pestis.
Journal of bacteriology 1989;171(10):5646-53.