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Beata Majchrzak

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Bhumika Sharma; Brady L Stein; Antonella Sassano; Priya Aggarwal; Jessica K Altman; Darren P Baker; Marinka Bulic; Eleanor N Fish; Rikiro Fukunaga; Sonali Joshi; Surinder Kaur; Jonathan D Licht; Beata Majchrzak; Brandon McMahon; Behnam Nabet; Leonidas C Platanias
Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responses.
Sonali Joshi; Bhumika Sharma; Surinder Kaur; Beata Majchrzak; Takeshi Ueda; Rikiro Fukunaga; Amit Verma; Eleanor N Fish; Leonidas C Platanias
Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis.
Simrit Parmar; Jessica Smith; Antonella Sassano; Shahab Uddin; Efstratios Katsoulidis; Beata Majchrzak; Suman Kambhampati; Elizabeth A Eklund; Martin S Tallman; Eleanor N Fish; Leonidas C Platanias
Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells.

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All Publications

2012: Bhumika Sharma; Brady L Stein; Antonella Sassano; Priya Aggarwal; Jessica K Altman; Darren P Baker; Marinka Bulic; Eleanor N Fish; Rikiro Fukunaga; Sonali Joshi; Surinder Kaur; Jonathan D Licht; Beata Majchrzak; Brandon McMahon; Behnam Nabet; Leonidas C Platanias
Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responses.
The Journal of biological chemistry 2012;287(50):42352-60.
2011: Sonali Joshi; Bhumika Sharma; Surinder Kaur; Beata Majchrzak; Takeshi Ueda; Rikiro Fukunaga; Amit Verma; Eleanor N Fish; Leonidas C Platanias
Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis.
The Journal of biological chemistry 2011;286(8):6017-26.
2005: Simrit Parmar; Jessica Smith; Antonella Sassano; Shahab Uddin; Efstratios Katsoulidis; Beata Majchrzak; Suman Kambhampati; Elizabeth A Eklund; Martin S Tallman; Eleanor N Fish; Leonidas C Platanias
Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells.
Blood 2005;106(7):2436-43.
2005: Surinder Kaur; Simrit Parmar; Jessica Smith; Efstratios Katsoulidis; Yongzhong Li; Antonella Sassano; Beata Majchrzak; Shahab Uddin; Martin S Tallman; Eleanor N Fish; Leonidas C Platanias
Role of protein kinase C-delta (PKC-delta) in the generation of the effects of IFN-alpha in chronic myelogenous leukemia cells.
Experimental hematology 2005;33(5):550-7.
2005: Yongzhong Li; Sandeep Batra; Antonella Sassano; Beata Majchrzak; David E Levy; Matthias Gaestel; Eleanor N Fish; Roger J Davis; Leonidas C Platanias
Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons.
The Journal of biological chemistry 2005;280(11):10001-10.
2004: Kishore K Srivastava; Sandeep Batra; Antonella Sassano; Yongzhong Li; Beata Majchrzak; Hiroaki Kiyokawa; Amnon Altman; Eleanor N Fish; Leonidas C Platanias
Engagement of protein kinase C-theta in interferon signaling in T-cells.
The Journal of biological chemistry 2004;279(29):29911-20.
2004: Simrit Parmar; Efstratios Katsoulidis; Amit Verma; Yongzhong Li; Antonella Sassano; Lakhvir Lal; Beata Majchrzak; Farhad Ravandi; Martin S Tallman; Eleanor N Fish; Leonidas C Platanias
Role of the p38 mitogen-activated protein kinase pathway in the generation of the effects of imatinib mesylate (STI571) in BCR-ABL-expressing cells.
The Journal of biological chemistry 2004;279(24):25345-52.
2004: Fatima Lekmine; Antonella Sassano; Shahab Uddin; Jessica Smith; Beata Majchrzak; Saskia M Brachmann; Nissim Hay; Eleanor N Fish; Leonidas C Platanias
Interferon-gamma engages the p70 S6 kinase to regulate phosphorylation of the 40S S6 ribosomal protein.
Experimental cell research 2004;295(1):173-82.
2004: Yongzhong Li; Antonella Sassano; Beata Majchrzak; Dilip K Deb; David E Levy; Matthias Gaestel; Angel R Nebreda; Eleanor N Fish; Leonidas C Platanias
Role of p38alpha Map kinase in Type I interferon signaling.
The Journal of biological chemistry 2004;279(2):970-9.
2003: Suman Kambhampati; Yongzhong Li; Amit Verma; Antonella Sassano; Beata Majchrzak; Dilip K Deb; Simrit Parmar; Nick Giafis; Dhan V Kalvakolanu; Arshad Rahman; Shahab Uddin; Saverio Minucci; Martin S Tallman; Eleanor N Fish; Leonidas C Platanias
Activation of protein kinase C delta by all-trans-retinoic acid.
The Journal of biological chemistry 2003;278(35):32544-51.
2003: Fatima Lekmine; Shahab Uddin; Antonella Sassano; Simrit Parmar; Saskia M Brachmann; Beata Majchrzak; Nahum Sonenberg; Nissim Hay; Eleanor N Fish; Leonidas C Platanias
Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.
The Journal of biological chemistry 2003;278(30):27772-80.
2003: Dilip K Deb; Antonella Sassano; Fatima Lekmine; Beata Majchrzak; Amit Verma; Suman Kambhampati; Shahab Uddin; Arshad Rahman; Eleanor N Fish; Leonidas C Platanias
Activation of protein kinase C delta by IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):267-73.
2003: Thomas Wong; Beata Majchrzak; Earl R Bogoch; Edward C Keystone; Eleanor N Fish
Therapeutic implications for interferon-alpha in arthritis: a pilot study.
The Journal of rheumatology 2003;30(5):934-40.
2002: Shahab Uddin; Antonella Sassano; Dilip K Deb; Amit Verma; Beata Majchrzak; Arshad Rahman; Asrar B Malik; Eleanor N Fish; Leonidas C Platanias
Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.
The Journal of biological chemistry 2002;277(17):14408-16.
2002: Fatima Lekmine; Antonella Sassano; Shahab Uddin; Beata Majchrzak; Osamu Miura; Brian J Druker; Eleanor N Fish; Akira Imamoto; Leonidas C Platanias
The CrkL adapter protein is required for type I interferon-dependent gene transcription and activation of the small G-protein Rap1.
Biochemical and biophysical research communications 2002;291(4):744-50.
2001: IA Mayer; Amit Verma; IM Grumbach; Shahab Uddin; Fatima Lekmine; Farhad Ravandi; Beata Majchrzak; S Fujita; Eleanor N Fish; Leonidas C Platanias
The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells.
The Journal of biological chemistry 2001;276(30):28570-7.
2001: M Wong; Shahab Uddin; Beata Majchrzak; T Huynh; A E Proudfoot; Leonidas C Platanias; Eleanor N Fish
Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells.
The Journal of biological chemistry 2001;276(14):11427-31.
2001: IM Grumbach; IA Mayer; Shahab Uddin; Fatima Lekmine; Beata Majchrzak; H Yamauchi; S Fujita; Brian J Druker; Eleanor N Fish; Leonidas C Platanias
Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL-expressing cells.
British journal of haematology 2001;112(2):327-36.
2000: Shahab Uddin; Fatima Lekmine; N Sharma; Beata Majchrzak; IA Mayer; Peter Young; G M Bokoch; Eleanor N Fish; Leonidas C Platanias
The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon alpha-dependent transcriptional activation but not serine phosphorylation of Stat proteins.
The Journal of biological chemistry 2000;275(36):27634-40.
2000: D Russell-Harde; T Charis Wagner; M R Sandhya Rani; David Vogel; Oscar R Colamonici; Richard M Ransohoff; Beata Majchrzak; Eleanor N Fish; H Daniel Perez; Ed Croze
Role of the intracellular domain of the human type I interferon receptor 2 chain (IFNAR2c) in interferon signaling. Expression of IFNAR2c truncation mutants in U5A cells.
The Journal of biological chemistry 2000;275(31):23981-5.
2000: Shahab Uddin; Beata Majchrzak; P C Wang; S Modi; M K Khan; Eleanor N Fish; Leonidas C Platanias
Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
Biochemical and biophysical research communications 2000;270(1):158-62.
2000: YM Alsayed; Shahab Uddin; S Ahmad; Beata Majchrzak; Brian J Druker; Eleanor N Fish; Leonidas C Platanias
IFN-gamma activates the C3G/Rap1 signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):1800-6.
1999: Shahab Uddin; Beata Majchrzak; J Woodson; P Arunkumar; YM Alsayed; R Pine; Peter Young; Eleanor N Fish; Leonidas C Platanias
Activation of the p38 mitogen-activated protein kinase by type I interferons.
The Journal of biological chemistry 1999;274(42):30127-31.
1999: IM Grumbach; Eleanor N Fish; Shahab Uddin; Beata Majchrzak; Oscar R Colamonici; Hans R Figulla; Albert Heim; Leonidas C Platanias
Activation of the Jak-Stat pathway in cells that exhibit selective sensitivity to the antiviral effects of IFN-beta compared with IFN-alpha.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(7):797-801.
1999: Owen W Nadeau; Paul Domanski; Anna Usacheva; Shahab Uddin; Leonidas C Platanias; PAULA PITHA-ROWE; R Raz; D Levy; Beata Majchrzak; Eleanor N Fish; Oscar R Colamonici
The proximal tyrosines of the cytoplasmic domain of the beta chain of the type I interferon receptor are essential for signal transducer and activator of transcription (Stat) 2 activation. Evidence that two Stat2 sites are required to reach a threshold of interferon alpha-induced Stat2 tyrosine phosphorylation that allows normal formation of interferon-stimulated gene factor 3.
The Journal of biological chemistry 1999;274(7):4045-52.
1999: Eleanor N Fish; Shahab Uddin; M Korkmaz; Beata Majchrzak; Brian J Druker; Leonidas C Platanias
Activation of a CrkL-stat5 signaling complex by type I interferons.
The Journal of biological chemistry 1999;274(2):571-3.