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Gerard Majeau

Research Profile

Living Beings

Chemicals & Drugs

Physiology

Lymphocyte Activation

Anatomy

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Drug Dose Response Relationship

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Publications

TOP 3
Sanchaita Sriwal Sonar; Yen-Ming Hsu; Melanie Lynn Conrad; Gerard R Majeau; Ayse Kilic; Ellen Garber; Yan Gao; Chioma Nwankwo; Gundi Willer; Jan C Dudda; Hellen Kim; Véronique Bailly; Axel Pagenstecher; Paul D Rennert; Harald Renz
Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma.
Michael L Dustin; Toby Starr; Daniel Coombs; Gerard R Majeau; Werner Meier; Paula S Hochman; Adam Douglass; Ronald D Vale; Byron Goldstein; Adrian Whitty
Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion.
Irene Sizing; Véronique Bailly; Patricia McCoon; Wenjie Chang; Sambasiva Rao; Lourdes Pablo; Rachel Rennard; Meghan Walsh; Zhifang Li; Mohammad Zafari; Max Dobles; Leticia Tarilonte; Steven Miklasz; Gerard R Majeau; Kevin Godbout; Martin L Scott; Paul D Rennert
Epitope-dependent effect of anti-murine TIM-1 monoclonal antibodies on T cell activity and lung immune responses.

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All Publications

2010: Sanchaita Sriwal Sonar; Yen-Ming Hsu; Melanie Lynn Conrad; Gerard R Majeau; Ayse Kilic; Ellen Garber; Yan Gao; Chioma Nwankwo; Gundi Willer; Jan C Dudda; Hellen Kim; Véronique Bailly; Axel Pagenstecher; Paul D Rennert; Harald Renz
Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma.
The Journal of clinical investigation 2010;120(8):2767-81.
2007: Michael L Dustin; Toby Starr; Daniel Coombs; Gerard R Majeau; Werner Meier; Paula S Hochman; Adam Douglass; Ronald D Vale; Byron Goldstein; Adrian Whitty
Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion.
The Journal of biological chemistry 2007;282(48):34748-57.
2007: Irene Sizing; Véronique Bailly; Patricia McCoon; Wenjie Chang; Sambasiva Rao; Lourdes Pablo; Rachel Rennard; Meghan Walsh; Zhifang Li; Mohammad Zafari; Max Dobles; Leticia Tarilonte; Steven Miklasz; Gerard R Majeau; Kevin Godbout; Martin L Scott; Paul D Rennert
Epitope-dependent effect of anti-murine TIM-1 monoclonal antibodies on T cell activity and lung immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2249-61.
2005: Tatiana I Novobrantseva; Gerard R Majeau; Aldo Amatucci; Sophia Kogan; Ian Brenner; Stefano Casola; Mark J Shlomchik; Victor E Koteliansky; Paula S Hochman; Alexander Ibraghimov
Attenuated liver fibrosis in the absence of B cells.
The Journal of clinical investigation 2005;115(11):3072-82.
2004: Jochen Mattner; Alexandra Wandersee-Steinhäuser; Andreas Pahl; Martin Röllinghoff; Gerard R Majeau; Paula S Hochman; Christian Bogdan
Protection against progressive leishmaniasis by IFN-beta.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7574-82.
2003: Kalpit A Vora; Li Chun Wang; Sambasiva P Rao; Zhong-Ying Liu; Gerard R Majeau; Anne H Cutler; Paula S Hochman; Martin L Scott; Susan L Kalled
Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and function.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):547-51.
2003: Joanne C Cooper; Geoffrey Morgan; Susanne Harding; Meena Subramanyam; Gerard R Majeau; Kevin Moulder; Denis R Alexander
Alefacept selectively promotes NK cell-mediated deletion of CD45R0+ human T cells.
European journal of immunology 2003;33(3):666-75.
2002: Antonio J da Silva; Margot Brickelmaier; Gerard R Majeau; Zhifang Li; Lihe Su; Yen-Ming Hsu; Paula S Hochman
Alefacept, an immunomodulatory recombinant LFA-3/IgG1 fusion protein, induces CD16 signaling and CD2/CD16-dependent apoptosis of CD2(+) cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4462-71.
2002: Antonio J da Silva; Margot Brickelmaier; Gerard R Majeau; Alexander V Lukashin; John Peyman; Adrian Whitty; Paula S Hochman
Comparison of gene expression patterns induced by treatment of human umbilical vein endothelial cells with IFN-alpha 2b vs. IFN-beta 1a: understanding the functional relationship between distinct type I interferons that act through a common receptor.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2002;22(2):173-88.
1999: Gerard R Majeau; Adrian Whitty; K Yim; Werner Meier; Paula S Hochman
Low affinity binding of an LFA-3/IgG1 fusion protein to CD2+ T cells is independent of cell activation.
Cell adhesion and communication 1999;7(3):267-79.
1997: Jeffrey L Browning; Irene Sizing; P Lawton; PR Bourdon; Paul D Rennert; Gerard R Majeau; Christine Ambrose; Cathy Hession; Konrad Miatkowski; D A Griffiths; Apinya Ngam-Ek; Werner Meier; Christopher D Benjamin; Paula S Hochman
Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3288-98.
1997: Fabienne Mackay; Gerard R Majeau; P Lawton; Paula S Hochman; Jeffrey L Browning
Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice.
European journal of immunology 1997;27(8):2033-42.
1996: Fabienne Mackay; Gerard R Majeau; Paula S Hochman; Jeffrey L Browning
Lymphotoxin beta receptor triggering induces activation of the nuclear factor kappaB transcription factor in some cell types.
The Journal of biological chemistry 1996;271(40):24934-8.
1995: Werner Meier; A Gill; M Rogge; R Dabora; Gerard R Majeau; F B Oleson; W E Jones; D Frazier; Konrad Miatkowski; Paula S Hochman
Immunomodulation by LFA3TIP, an LFA-3/IgG1 fusion protein: cell line dependent glycosylation effects on pharmacokinetics and pharmacodynamic markers.
Therapeutic immunology 1995;2(3):159-71.
1995: Paula S Hochman; Gerard R Majeau; Fabienne Mackay; Jeffrey L Browning
Proinflammatory responses are efficiently induced by homotrimeric but not heterotrimeric lymphotoxin ligands.
Journal of inflammation 1995;46(4):220-34.
1994: P L Chisholm; C A Williams; W E Jones; Gerard R Majeau; F B Oleson; B Burrus-Fischer; Werner Meier; Paula S Hochman
The effects of an immunomodulatory LFA3-IgG1 fusion protein on nonhuman primates.
Therapeutic immunology 1994;1(4):205-16.
1994: Gerard R Majeau; Werner Meier; B Jimmo; D Kioussis; Paula S Hochman
Mechanism of lymphocyte function-associated molecule 3-Ig fusion proteins inhibition of T cell responses. Structure/function analysis in vitro and in human CD2 transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(6):2753-67.