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Philip Majerus

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Jun Zou; Chunfen Zhang; Marina V Kisseleva; Philip W Majerus; Jasna Marjanovic; Monita P Wilson
Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8.
Chunfen Zhang; Philip W Majerus; Monita P Wilson
Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation.
Jun Zou; Shao-Chun Chang; Philip W Majerus; Anja Schrade; David B Wilson; Monita P Wilson
The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death.

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2012: Jun Zou; Chunfen Zhang; Marina V Kisseleva; Philip W Majerus; Jasna Marjanovic; Monita P Wilson
Myotubularin-related protein (MTMR) 9 determines the enzymatic activity, substrate specificity, and role in autophagy of MTMR8.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(24):9539-44.
2012: Chunfen Zhang; Philip W Majerus; Monita P Wilson
Regulation of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(7):2290-5.
2012: Jun Zou; Shao-Chun Chang; Philip W Majerus; Anja Schrade; David B Wilson; Monita P Wilson
The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death.
Advances in biological regulation 2012;52(1):282-9.
2011: Philip W Majerus
Wandering through the laboratory.
The Journal of biological chemistry 2011;286(7):4941-5.
2010: Clare G Fedele; Lisa M Ooms; Miriel Ho; Jessica Vieusseux; Sandra Alison O'Toole; Ewan K Millar; Elena Lopez-Knowles; Absorn Sriratana; Rajendra Gurung; Laura Baglietto; Graham G Giles; Charles G Bailey; John Rasko; Benjamin J Shields; John T Price; Philip W Majerus; Robert L Sutherland; Tony Tiganis; Catriona A McLean; Christina A Mitchell
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(51):22231-6.
2010: Philip W Majerus; David B Wilson; Chunfen Zhang; Peter J Nicholas; Monita P Wilson
Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects.
Advances in enzyme regulation 2010;50(1):365-72.
2009: Stephanie L Bielas; Jennifer L Silhavy; Francesco Brancati; Marina V Kisseleva; Lihadh Al-Gazali; Laszlo Sztriha; Riad A Bayoumi; Maha S Zaki; Alice Abdel-Aleem; Rasim Ozgur Rosti; Hulya Kayserili; Dominika Swistun; Lesley C Scott; Enrico Bertini; Eugen Boltshauser; Elisa Fazzi; Lorena Travaglini; Seth J Field; Stephanie Gayral; Monique Jacoby; Stephane Schurmans; Bruno Dallapiccola; Philip W Majerus; Enza Maria Valente; Joseph G Gleeson
Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies.
Nature genetics 2009;41(9):1032-6.
2009: Ivan Ivetac; Rajendra Gurung; Sandra Hakim; Kristy A Horan; David A Sheffield; Lauren C Binge; Philip W Majerus; Tony Tiganis; Christina A Mitchell
Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1.
EMBO reports 2009;10(5):487-93.
2009: Philip W Majerus; John D York
Phosphoinositide phosphatases and disease.
Journal of lipid research 2009;50 Suppl():S249-54.
2009: Jun Zou; Shao-Chun Chang; Jasna Marjanovic; Philip W Majerus
MTMR9 increases MTMR6 enzyme activity, stability, and role in apoptosis.
The Journal of biological chemistry 2009;284(4):2064-71.
2008: Philip W Majerus; Jun Zou; Jasna Marjanovic; Marina V Kisseleva; Monita P Wilson
The role of inositol signaling in the control of apoptosis.
Advances in enzyme regulation 2008;48():10-7.
2007: Philip W Majerus
A discrete signaling function for an inositol pyrophosphate.
Science's STKE : signal transduction knowledge environment 2007;2007(416):pe72.
2007: Jun Zou; Jasna Marjanovic; Marina V Kisseleva; Monita Wilson; Philip W Majerus
Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(43):16834-9.
2006: Shao-Chun Chang; Philip W Majerus
Inositol polyphosphate multikinase regulates inositol 1,4,5,6-tetrakisphosphate.
Biochemical and biophysical research communications 2006;339(1):209-16.
2005: Alexander Ungewickell; Christopher Hugge; Marina V Kisseleva; Shao-Chun Chang; Jun Zou; Yucheng Feng; Edouard E Galyov; Monita Wilson; Philip W Majerus
The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(52):18854-9.
2005: John Verbsky; Philip W Majerus
Increased levels of inositol hexakisphosphate (InsP6) protect HEK293 cells from tumor necrosis factor (alpha)- and Fas-induced apoptosis.
The Journal of biological chemistry 2005;280(32):29263-8.
2005: John Verbsky; Kory Lavine; Philip W Majerus
Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(24):8448-53.
2005: Ivan Ivetac; Adam D Munday; Marina V Kisseleva; Xiang-Ming Zhang; Susan Luff; Tony Tiganis; James C Whisstock; Tony Rowe; Philip W Majerus; Christina A Mitchell
The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane.
Molecular biology of the cell 2005;16(5):2218-33.
2005: Gregory Miller; Monita P Wilson; Philip W Majerus; James H Hurley
Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase.
Molecular cell 2005;18(2):201-12.
2005: John Verbsky; Shao-Chun Chang; Monita P Wilson; Yasuhiro Mochizuki; Philip W Majerus
The pathway for the production of inositol hexakisphosphate in human cells.
The Journal of biological chemistry 2005;280(3):1911-20.
2004: Alexander Ungewickell; Michael E Ward; Ernst J Ungewickell; Philip W Majerus
The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(37):13501-6.
2004: Heidi J Rayala; Frederic Kendirgi; Dianne M Barry; Philip W Majerus; Susan R Wente
The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155.
Molecular & cellular proteomics : MCP 2004;3(2):145-55.
2003: Young Sun; Yasuhiro Mochizuki; Philip W Majerus
Inositol 1,3,4-trisphosphate 5/6-kinase inhibits tumor necrosis factor-induced apoptosis.
The Journal of biological chemistry 2003;278(44):43645-53.
2003: Yasuhiro Mochizuki; Philip W Majerus
Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9768-73.
2003: Harshal H Nandurkar; Meredith Layton; Jocelyn Laporte; Carly Selan; Lisa Corcoran; Kevin K Caldwell; Yasuhiro Mochizuki; Philip W Majerus; Christina A Mitchell
Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8660-5.
2002: Young Sun; Monita P Wilson; Philip W Majerus
Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1.
The Journal of biological chemistry 2002;277(48):45759-64.
2002: Shao-Chun Chang; Aimee L Miller; Yucheng Feng; Susan R Wente; Philip W Majerus
The human homolog of the rat inositol phosphate multikinase is an inositol 1,3,4,6-tetrakisphosphate 5-kinase.
The Journal of biological chemistry 2002;277(46):43836-43.
2002: John Verbsky; Monita P Wilson; Marina V Kisseleva; Philip W Majerus; Susan R Wente
The synthesis of inositol hexakisphosphate. Characterization of human inositol 1,3,4,5,6-pentakisphosphate 2-kinase.
The Journal of biological chemistry 2002;277(35):31857-62.
2002: Marina V Kisseleva; Li Cao; Philip W Majerus
Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits Akt/protein kinase B phosphorylation and leads to apoptotic cell death.
The Journal of biological chemistry 2002;277(8):6266-72.
2001: Monita P Wilson; Young Sun; L Cao; Philip W Majerus
Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2.
The Journal of biological chemistry 2001;276(44):40998-1004.
2001: Harshal H Nandurkar; Kevin K Caldwell; James C Whisstock; Meredith J Layton; EA Gaudet; FA Norris; Philip W Majerus; Christina A Mitchell
Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: identification of a myotubularin-related protein lacking catalytic activity.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9499-504.
2001: Y Feng; Susan R Wente; Philip W Majerus
Overexpression of the inositol phosphatase SopB in human 293 cells stimulates cellular chloride influx and inhibits nuclear mRNA export.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):875-9.
2000: Paresh Vyas; FA Norris; R Joseph; Philip W Majerus; Stuart H Orkin
Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(25):13696-701.
2000: Marina V Kisseleva; Monita P Wilson; Philip W Majerus
The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase.
The Journal of biological chemistry 2000;275(26):20110-6.
2000: Jessica Field; Monita P Wilson; Z Mai; Philip W Majerus; John Samuelson
An Entamoeba histolytica inositol 1,3,4-trisphosphate 5/6-kinase has a novel 3-kinase activity.
Molecular and biochemical parasitology 2000;108(1):119-23.
2000: Jeannette Kunz; Monita P Wilson; Marina V Kisseleva; James H Hurley; Philip W Majerus; Richard A Anderson
The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity.
Molecular cell 2000;5(1):1-11.
1999: Alexander Ungewickell; Philip W Majerus
Increased levels of plasma lysosomal enzymes in patients with Lowe syndrome.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13342-4.
1999: Philip W Majerus; Marina V Kisseleva; FA Norris
The role of phosphatases in inositol signaling reactions.
The Journal of biological chemistry 1999;274(16):10669-72.
1999: Adam D Munday; FA Norris; Kevin K Caldwell; S Brown; Philip W Majerus; Christina A Mitchell
The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3640-5.
1998: FA Norris; Monita P Wilson; T S Wallis; Edouard E Galyov; Philip W Majerus
SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14057-9.
1998: Jacqueline E Damen; L Liu; MD Ware; M Ermolaeva; Philip W Majerus; Gerald Krystal
Multiple forms of the SH2-containing inositol phosphatase, SHIP, are generated by C-terminal truncation.
Blood 1998;92(4):1199-205.
1998: X Zhang; Philip W Majerus
Phosphatidylinositol signalling reactions.
Seminars in cell & developmental biology 1998;9(2):153-60.
1998: Philip W Majerus
Prostaglandins: critical roles in pregnancy and colon cancer.
Current biology : CB 1998;8(3):R87-9.
1998: X Zhang; P A Hartz; E Philip; Lorraine C Racusen; Philip W Majerus
Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate.
The Journal of biological chemistry 1998;273(3):1574-82.
1997: FA Norris; R C Atkins; Philip W Majerus
The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family.
The Journal of biological chemistry 1997;272(38):23859-64.
1997: X Zhang; JC Loijens; IV Boronenkov; GJ Parker; FA Norris; J Chen; Oliver Thum; G D Prestwich; Philip W Majerus; Richard A Anderson
Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules.
The Journal of biological chemistry 1997;272(28):17756-61.
1997: FA Norris; R C Atkins; Philip W Majerus
Inositol polyphosphate 4-phosphatase is inactivated by calpain-mediated proteolysis in stimulated human platelets.
The Journal of biological chemistry 1997;272(17):10987-9.
1997: Jacqueline E Damen; L Liu; H Wakao; Atsushi Miyajima; Patricia M Rosten; A B Jefferson; Philip W Majerus; Jana Krosl; R Keith Humphries; Gerald Krystal
The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation.
Leukemia 1997;11 Suppl 3():423-5.
1997: Monita P Wilson; Philip W Majerus
Characterization of a cDNA encoding Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase.
Biochemical and biophysical research communications 1997;232(3):678-81.
1997: AB Jefferson; V Auethavekiat; David Pot; LT Williams; Philip W Majerus
Signaling inositol polyphosphate-5-phosphatase. Characterization of activity and effect of GRB2 association.
The Journal of biological chemistry 1997;272(9):5983-8.
1997: V Auethavekiat; C S Abrams; Philip W Majerus
Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I.
The Journal of biological chemistry 1997;272(3):1786-90.
1996: Lidong Liu; A B Jefferson; X Zhang; F A Norris; Philip W Majerus; Gerald Krystal
A novel phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase associates with the interleukin-3 receptor.
The Journal of biological chemistry 1996;271(47):29729-33.
1996: M Gu; K Meng; Philip W Majerus
The effect of overexpression of the protein tyrosine phosphatase PTPMEG on cell growth and on colony formation in soft agar in COS-7 cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):12980-5.
1996: M Gu; Philip W Majerus
The properties of the protein tyrosine phosphatase PTPMEG.
The Journal of biological chemistry 1996;271(44):27751-9.
1996: A B Jefferson; Philip W Majerus
Mutation of the conserved domains of two inositol polyphosphate 5-phosphatases.
Biochemistry 1996;35(24):7890-4.
1996: M P Wilson; Philip W Majerus
Isolation of inositol 1,3,4-trisphosphate 5/6-kinase, cDNA cloning and expression of the recombinant enzyme.
The Journal of biological chemistry 1996;271(20):11904-10.
1996: Philip W Majerus
Inositols do it all.
Genes & development 1996;10(9):1051-3.
1996: WM Kavanaugh; David Pot; S M Chin; M Deuter-Reinhard; A B Jefferson; F A Norris; F R Masiarz; L S Cousens; Philip W Majerus; LT Williams
Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2.
Current biology : CB 1996;6(4):438-45.
1996: Jacqueline E Damen; Lidong Liu; Patricia M Rosten; R Keith Humphries; A B Jefferson; Philip W Majerus; Gerald Krystal
The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1689-93.
1995: FA Norris; V Auethavekiat; Philip W Majerus
The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase.
The Journal of biological chemistry 1995;270(27):16128-33.
1995: J D York; J W Ponder; Philip W Majerus
Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):5149-53.
1995: X Zhang; A B Jefferson; V Auethavekiat; Philip W Majerus
The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4853-6.
1995: FA Norris; E Ungewickell; Philip W Majerus
Inositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitro.
The Journal of biological chemistry 1995;270(1):214-7.
1994: J D York; J W Ponder; Z W Chen; F S Mathews; Philip W Majerus
Crystal structure of inositol polyphosphate 1-phosphatase at 2.3-A resolution.
Biochemistry 1994;33(45):13164-71.
1994: FA Norris; Philip W Majerus
Hydrolysis of phosphatidylinositol 3,4-bisphosphate by inositol polyphosphate 4-phosphatase isolated by affinity elution chromatography.
The Journal of biological chemistry 1994;269(12):8716-20.
1994: J D York; Philip W Majerus
Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells.
The Journal of biological chemistry 1994;269(11):7847-50.
1994: J D York; Z W Chen; J W Ponder; A K Chauhan; F S Mathews; Philip W Majerus
Crystallization and initial X-ray crystallographic characterization of recombinant bovine inositol polyphosphate 1-phosphatase produced in Spodoptera frugiperda cells.
Journal of molecular biology 1994;236(2):584-9.
1993: J D York; Rosalie A Veile; H Donis-Keller; Philip W Majerus
Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5833-7.
1992: Theodora S Ross; Philip W Majerus
Identification of a phosphodiesterase that converts inositol cyclic 1:2-phosphate to inositol 2-phosphate.
The Journal of biological chemistry 1992;267(28):19924-8.
1992: Theodora S Ross; F P Wang; Philip W Majerus
Mammalian cells that express Bacillus cereus phosphatidylinositol-specific phospholipase C have increased levels of inositol cyclic 1:2-phosphate, inositol 1-phosphate, and inositol 2-phosphate.
The Journal of biological chemistry 1992;267(28):19919-23.
1992: M Gu; I Warshawsky; Philip W Majerus
Cloning and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14p.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2980-4.
1992: Philip W Majerus
Inositol phosphate biochemistry.
Annual review of biochemistry 1992;61():225-50.
1991: Theodora S Ross; A B Jefferson; C A Mitchell; Philip W Majerus
Cloning and expression of human 75-kDa inositol polyphosphate-5-phosphatase.
The Journal of biological chemistry 1991;266(30):20283-9.
1991: J P Walsh; K K Caldwell; Philip W Majerus
Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):9184-7.
1991: K K Caldwell; D L Lips; V S Bansal; Philip W Majerus
Isolation and characterization of two 3-phosphatases that hydrolyze both phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate.
The Journal of biological chemistry 1991;266(27):18378-86.
1991: M X Gu; J D York; I Warshawsky; Philip W Majerus
Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5867-71.
1991: Theodora S Ross; B Whiteley; R A Graham; Philip W Majerus
Cyclic hydrolase-transfected 3T3 cells have low levels of inositol 1,2-cyclic phosphate and reach confluence at low density.
The Journal of biological chemistry 1991;266(14):9086-92.
1991: T W Cunningham; Philip W Majerus
Pathway for the formation of D-3 phosphate containing inositol phospholipids in PDGF stimulated NIH 3T3 fibroblasts.
Biochemical and biophysical research communications 1991;175(2):568-76.
1991: Theodora S Ross; Philip W Majerus
Inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase. Substrate specificity and regulation of activity by phospholipids, metal ion chelators, and inositol 2-phosphate.
The Journal of biological chemistry 1991;266(2):851-6.
1991: Philip W Majerus; V S Bansal; D L Lips; Theodora S Ross; C A Mitchell; K K Caldwell; T W Cunningham
The phosphatidylinositol pathway of platelets and vascular cells.
Annals of the New York Academy of Sciences 1991;614():44-50.
1991: Philip W Majerus
The George M. Kober Lecture: molecular mechanisms of intracellular signal transduction.
Transactions of the Association of American Physicians 1991;104():clxviii-clxxx.
1990: T W Cunningham; D L Lips; V S Bansal; K K Caldwell; C A Mitchell; Philip W Majerus
Pathway for the formation of D-3 phosphate containing inositol phospholipids in intact human platelets.
The Journal of biological chemistry 1990;265(35):21676-83.
1990: J D York; Philip W Majerus
Isolation and heterologous expression of a cDNA encoding bovine inositol polyphosphate 1-phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9548-52.
1990: C A Mitchell; A B Jefferson; B E Bejeck; Joan S Brugge; T F Deuel; Philip W Majerus
Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9396-400.
1990: Philip W Majerus; Theodora S Ross; T W Cunningham; K K Caldwell; A B Jefferson; V S Bansal
Recent insights in phosphatidylinositol signaling.
Cell 1990;63(3):459-65.
1990: Theodora S Ross; J F Tait; Philip W Majerus
Identity of inositol 1,2-cyclic phosphate 2-phosphohydrolase with lipocortin III.
Science (New York, N.Y.) 1990;248(4955):605-7.
1990: V S Bansal; K K Caldwell; Philip W Majerus
The isolation and characterization of inositol polyphosphate 4-phosphatase.
The Journal of biological chemistry 1990;265(3):1806-11.
1990: W A Dittman; Philip W Majerus
Structure and function of thrombomodulin: a natural anticoagulant.
Blood 1990;75(2):329-36.
1990: V S Bansal; Philip W Majerus
Phosphatidylinositol-derived precursors and signals.
Annual review of cell biology 1990;6():41-67.
1989: D L Lips; Philip W Majerus
The discovery of a 3-phosphomonoesterase that hydrolyzes phosphatidylinositol 3-phosphate in NIH 3T3 cells.
The Journal of biological chemistry 1989;264(33):19911-5.
1989: W A Dittman; T Kumada; Philip W Majerus
Transcription of thrombomodulin mRNA in mouse hemangioma cells is increased by cycloheximide and thrombin.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(18):7179-82.
1989: C A Mitchell; T M Connolly; Philip W Majerus
Identification and isolation of a 75-kDa inositol polyphosphate-5-phosphatase from human platelets.
The Journal of biological chemistry 1989;264(15):8873-7.
1989: D L Lips; Philip W Majerus; F R Gorga; A T Young; Thomas L Benjamin
Phosphatidylinositol 3-phosphate is present in normal and transformed fibroblasts and is resistant to hydrolysis by bovine brain phospholipase C II.
The Journal of biological chemistry 1989;264(15):8759-63.
1989: W A Dittman; Philip W Majerus
Sequence of a cDNA for mouse thrombomodulin and comparison of the predicted mouse and human amino acid sequences.
Nucleic acids research 1989;17(2):802.
1988: W A Dittman; T Kumada; J Evan Sadler; Philip W Majerus
The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells.
The Journal of biological chemistry 1988;263(30):15815-22.
1988: R C Inhorn; Philip W Majerus
Properties of inositol polyphosphate 1-phosphatase.
The Journal of biological chemistry 1988;263(28):14559-65.
1988: Philip W Majerus; T M Connolly; V S Bansal; R C Inhorn; Theodora S Ross; D L Lips
Inositol phosphates: synthesis and degradation.
The Journal of biological chemistry 1988;263(7):3051-4.
1988: T Kumada; W A Dittman; Philip W Majerus
A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice.
Blood 1988;71(3):728-33.
1988: D L Lips; T E Bross; Philip W Majerus
Isolation of 1-monomethylphosphoinositol 4,5-bisphosphate [a product of methanolysis of inositol 1,2-(cyclic)-4,5-trisphosphate] from Swiss mouse 3T3 cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(1):88-92.
1987: R C Inhorn; Philip W Majerus
Inositol polyphosphate 1-phosphatase from calf brain. Purification and inhibition by Li+, Ca2+, and Mn2+.
The Journal of biological chemistry 1987;262(33):15946-52.
1987: V S Bansal; R C Inhorn; Philip W Majerus
The metabolism of inositol 1,3,4-trisphosphate to inositol 1,3-bisphosphate.
The Journal of biological chemistry 1987;262(20):9444-7.
1987: D Z Wen; W A Dittman; Richard D Ye; L L Deaven; Philip W Majerus; J Evan Sadler
Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene.
Biochemistry 1987;26(14):4350-7.
1987: R C Inhorn; V S Bansal; Philip W Majerus
Pathway for inositol 1,3,4-trisphosphate and 1,4-bisphosphate metabolism.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(8):2170-4.
1987: T M Connolly; V S Bansal; T E Bross; R F Irvine; Philip W Majerus
The metabolism of tris- and tetraphosphates of inositol by 5-phosphomonoesterase and 3-kinase enzymes.
The Journal of biological chemistry 1987;262(5):2146-9.
1987: D B Wilson; T M Connolly; Theodora S Ross; H Ishii; T E Bross; H Deckmyn; L F Brass; Philip W Majerus
Phosphoinositide metabolism in human platelets.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17A():558-62.
1986: Philip W Majerus; T M Connolly; H Deckmyn; Theodora S Ross; T E Bross; H Ishii; V S Bansal; D B Wilson
The metabolism of phosphoinositide-derived messenger molecules.
Science (New York, N.Y.) 1986;234(4783):1519-26.
1986: H Ishii; T M Connolly; T E Bross; Philip W Majerus
Inositol cyclic triphosphate [inositol 1,2-(cyclic)-4,5-triphosphate] is formed upon thrombin stimulation of human platelets.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(17):6397-401.
1986: T M Connolly; D B Wilson; T E Bross; Philip W Majerus
Isolation and characterization of the inositol cyclic phosphate products of phosphoinositide cleavage by phospholipase C. Metabolism in cell-free extracts.
The Journal of biological chemistry 1986;261(1):122-6.
1986: Philip W Majerus; T M Connolly; T S Ross; H Ishii; H Deckmyn
The role of phosphoinositides in cell physiology.
Symposium on Fundamental Cancer Research 1986;39():157-63.
1985: D B Wilson; T M Connolly; T E Bross; Philip W Majerus; W R Sherman; A N Tyler; L J Rubin; J E Brown
Isolation and characterization of the inositol cyclic phosphate products of polyphosphoinositide cleavage by phospholipase C. Physiological effects in permeabilized platelets and Limulus photoreceptor cells.
The Journal of biological chemistry 1985;260(25):13496-501.
1985: T M Connolly; T E Bross; Philip W Majerus
Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate.
The Journal of biological chemistry 1985;260(13):7868-74.
1985: D B Wilson; T E Bross; W R Sherman; R A Berger; Philip W Majerus
Inositol cyclic phosphates are produced by cleavage of phosphatidylphosphoinositols (polyphosphoinositides) with purified sheep seminal vesicle phospholipase C enzymes.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(12):4013-7.
1985: Philip W Majerus; D B Wilson; T M Connolly; T E Bross; E J Neufeld
Pathways of phosphoinositide metabolism in human platelets.
Advances in prostaglandin, thromboxane, and leukotriene research 1985;15():109-12.
1984: E J Neufeld; T E Bross; Philip W Majerus
A mutant HSDM1C1 fibrosarcoma line selected for defective eicosanoid precursor uptake lacks arachidonate-specific acyl-CoA synthetase.
The Journal of biological chemistry 1984;259(3):1986-92.