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Edwin Mak

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Jacob A Udell; Charlie S Wang; Najib T Ayas; J Mark FitzGerald; Edwin Mak; Michael Schulzer; David L Simel; Jill Tinmouth; Eric M Yoshida
Does this patient with liver disease have cirrhosis?
Ramachandiran Nandhagopal; Thomas J Ruth; Michael Schulzer; Vesna Sossi; Jacqueline Cragg; Raul de la Fuente-Fernandez; Lisa Kuramoto; Edwin Mak; Siobhan McCormick; Jess McKenzie; A Jon Stoessl
Longitudinal evolution of compensatory changes in striatal dopamine processing in Parkinson's disease.
Raúl de La Fuente-Fernández; Michael Schulzer; Lisa Kuramoto; Jacquelyn Cragg; Nandhagopal Ramachandiran; Wing L Au; Edwin Mak; Jess McKenzie; Siobhan McCormick; Vesna Sossi; Thomas J Ruth; Chong S Lee; Donald B Calne; A Jon Stoessl
Age-specific progression of nigrostriatal dysfunction in Parkinson's disease.

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All Publications

2012: Jacob A Udell; Charlie S Wang; Najib T Ayas; J Mark FitzGerald; Edwin Mak; Michael Schulzer; David L Simel; Jill Tinmouth; Eric M Yoshida
Does this patient with liver disease have cirrhosis?
JAMA : the journal of the American Medical Association 2012;307(8):832-42.
2011: Ramachandiran Nandhagopal; Thomas J Ruth; Michael Schulzer; Vesna Sossi; Jacqueline Cragg; Raul de la Fuente-Fernandez; Lisa Kuramoto; Edwin Mak; Siobhan McCormick; Jess McKenzie; A Jon Stoessl
Longitudinal evolution of compensatory changes in striatal dopamine processing in Parkinson's disease.
Brain : a journal of neurology 2011;134(Pt 11):3290-8.
2011: Raúl de La Fuente-Fernández; Michael Schulzer; Lisa Kuramoto; Jacquelyn Cragg; Nandhagopal Ramachandiran; Wing L Au; Edwin Mak; Jess McKenzie; Siobhan McCormick; Vesna Sossi; Thomas J Ruth; Chong S Lee; Donald B Calne; A Jon Stoessl
Age-specific progression of nigrostriatal dysfunction in Parkinson's disease.
Annals of neurology 2011;69(5):803-10.
2010: Vesna Sossi; Katherine Dinelle; Michael Schulzer; Edwin Mak; Doris J Doudet; Raúl de La Fuente-Fernández
Levodopa and pramipexole effects on presynaptic dopamine PET markers and estimated dopamine release.
European journal of nuclear medicine and molecular imaging 2010;37(12):2364-70.
2010: Raúl de La Fuente-Fernández; Michael Schulzer; Edwin Mak; Vesna Sossi
Trials of neuroprotective therapies for Parkinson's disease: problems and limitations.
Parkinsonism & related disorders 2010;16(6):365-9.
2010: Roy Purssell; Douglas Brown; Jeffery R Brubacher; Jean Wilson; Ming Fang; Michael Schulzer; Edwin Mak; Riyad B Abu-Laban; Richard Simons; Tristan Walker
Proportion of injured drivers presenting to a tertiary care emergency department who engage in future impaired driving activities.
Traffic injury prevention 2010;11(1):35-42.
2010: André R Troiano; Michael Schulzer; Raul de la Fuente-Fernandez; Edwin Mak; Jess McKenzie; Vesna Sossi; Siobhan McCormick; Thomas J Ruth; A Jon Stoessl
Dopamine transporter PET in normal aging: dopamine transporter decline and its possible role in preservation of motor function.
Synapse (New York, N.Y.) 2010;64(2):146-51.
2009: R Nandhagopal; Lisa Kuramoto; Michael Schulzer; Edwin Mak; J Cragg; Chong S Lee; J McKenzie; S McCormick; Ali Samii; André R Troiano; Thomas J Ruth; Vesna Sossi; Raul de la Fuente-Fernandez; Donald B Calne; A Jon Stoessl
Longitudinal progression of sporadic Parkinson's disease: a multi-tracer positron emission tomography study.
Brain : a journal of neurology 2009;132(Pt 11):2970-9.
2009: André R Troiano; R de la Fuente-Fernandez; Vesna Sossi; Michael Schulzer; Edwin Mak; Thomas J Ruth; A Jon Stoessl
PET demonstrates reduced dopamine transporter expression in PD with dyskinesias.
Neurology 2009;72(14):1211-6.
2008: R Nandhagopal; Edwin Mak; Michael Schulzer; J McKenzie; S McCormick; Vesna Sossi; Thomas J Ruth; A Strongosky; Matthew J Farrer; Zbigniew K Wszolek; A Jon Stoessl
Progression of dopaminergic dysfunction in a LRRK2 kindred: a multitracer PET study.
Neurology 2008;71(22):1790-5.
2007: M Alajmi; Alan T Mulgrew; J Fox; Warren Davidson; Michael Schulzer; Edwin Mak; C Frank Ryan; John A Fleetham; P Choi; Najib T Ayas
Impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopnea: a meta-analysis of randomized controlled trials.
Lung 2007;185(2):67-72.
2006: Warren J Davidson; Delbert R Dorscheid; Roger Spragg; Michael Schulzer; Edwin Mak; Najib T Ayas
Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: results of a meta-analysis.
Critical care (London, England) 2006;10(2):R41.
2005: John R Adams; Hinke van Netten; Michael Schulzer; Edwin Mak; Jessamyn Mckenzie; Audrey Strongosky; Vesna Sossi; Thomas J Ruth; Chong S Lee; Matthew J Farrer; Thomas Gasser; Ryan Uitti; Donald B Calne; Zbigniew K Wszolek; A Jon Stoessl
PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation.
Brain : a journal of neurology 2005;128(Pt 12):2777-85.
2005: Charlie S Wang; J Mark FitzGerald; Michael Schulzer; Edwin Mak; Najib T Ayas
Does this dyspneic patient in the emergency department have congestive heart failure?
JAMA : the journal of the American Medical Association 2005;294(15):1944-56.
2005: Carol Ann Courneya; Kristin Wright; Vera Frinton; Edwin Mak; Michael Schulzer; George Pachev
Medical student selection: choice of a semi-structured panel interview or an unstructured one-on-one interview.
Medical teacher 2005;27(6):499-503.
2005: Ednan K Bajwa; Najib T Ayas; Michael Schulzer; Edwin Mak; Jay H Ryu; Atul Malhotra
Interferon-gamma1b therapy in idiopathic pulmonary fibrosis: a metaanalysis.
Chest 2005;128(1):203-6.
2004: Chong S Lee; Michael Schulzer; Raúl de La Fuente-Fernández; Edwin Mak; Lisa Kuramoto; Vesna Sossi; Thomas J Ruth; Donald B Calne; A Jon Stoessl
Lack of regional selectivity during the progression of Parkinson disease: implications for pathogenesis.
Archives of neurology 2004;61(12):1920-5.
2004: Ajit Kumar; Susan M Calne; Michael Schulzer; Edwin Mak; Zbigniew K Wszolek; Chris van Netten; Joseph K C Tsui; A Jon Stoessl; Donald B Calne
Clustering of Parkinson disease: shared cause or coincidence?
Archives of neurology 2004;61(7):1057-60.
2004: Raúl de La Fuente-Fernández; Michael Schulzer; Edwin Mak; Donald B Calne; A Jon Stoessl
Presynaptic mechanisms of motor fluctuations in Parkinson's disease: a probabilistic model.
Brain : a journal of neurology 2004;127(Pt 4):888-99.
2003: Michael Schulzer; Edwin Mak; Susan M Calne
The psychometric properties of the Parkinson's Impact Scale (PIMS) as a measure of quality of life in Parkinson's disease.
Parkinsonism & related disorders 2003;9(5):291-4.
2003: Jason Carr; Raúl de La Fuente-Fernández; Michael Schulzer; Edwin Mak; Susan M Calne; Donald B Calne
Familial and sporadic Parkinson's disease usually display the same clinical features.
Parkinsonism & related disorders 2003;9(4):201-4.
2003: Susan M Calne; Edwin Mak; Jeanne Hall; Marie-Jose Fortin; Pamela King; Germaine McInnes; Linda Grantier; Sherree Trecartin; Michael Schulzer
Validating a quality-of-life scale in caregivers of patients with Parkinson's disease: Parkinson's Impact Scale (PIMS).
Advances in neurology 2003;91():115-22.
2000: Pramod Kumar Pal; Ali Samii; A Kishore; Michael Schulzer; Edwin Mak; S Yardley; IM Turnbull; Donald B Calne
Long term outcome of unilateral pallidotomy: follow up of 15 patients for 3 years.
Journal of neurology, neurosurgery, and psychiatry 2000;69(3):337-44.
2000: Pramod Kumar Pal; Ali Samii; Michael Schulzer; Edwin Mak; Joseph K C Tsui
Head tremor in cervical dystonia.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2000;27(2):137-42.
2000: Ali Samii; Pramod Kumar Pal; Michael Schulzer; Edwin Mak; Joseph K C Tsui
Post-traumatic cervical dystonia: a distinct entity?
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2000;27(1):55-9.
2000: Raúl de La Fuente-Fernández; Pramod Kumar Pal; FJ Vingerhoets; A Kishore; Michael Schulzer; Edwin Mak; Thomas J Ruth; BJ Snow; Donald B Calne; A Jon Stoessl
Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(1):49-57.
1999: Ali Samii; K Markopoulou; Zbigniew K Wszolek; Vesna Sossi; Teresa Dobko; Edwin Mak; Donald B Calne; A Jon Stoessl
PET studies of parkinsonism associated with mutation in the alpha-synuclein gene.
Neurology 1999;53(9):2097-102.
1999: Ali Samii; IM Turnbull; A Kishore; Michael Schulzer; Edwin Mak; S Yardley; Donald B Calne
Reassessment of unilateral pallidotomy in Parkinson's disease. A 2-year follow-up study.
Brain : a journal of neurology 1999;122 ( Pt 3)():417-25.
1998: Y Wang; GL Chan; James E Holden; Teresa Dobko; Edwin Mak; Michael Schulzer; J M Huser; BJ Snow; Thomas J Ruth; Donald B Calne; A Jon Stoessl
Age-dependent decline of dopamine D1 receptors in human brain: a PET study.
Synapse (New York, N.Y.) 1998;30(1):56-61.
1998: Raul de la Fuente-Fernandez; Michael Schulzer; Edwin Mak; A Kishore; Donald B Calne
The role of the Lewy body in idiopathic Parkinsonism.
Parkinsonism & related disorders 1998;4(2):73-7.
1998: A Kishore; T G Nygaard; Raul de la Fuente-Fernandez; A B Naini; Michael Schulzer; Edwin Mak; Thomas J Ruth; Donald B Calne; BJ Snow; A Jon Stoessl
Striatal D2 receptors in symptomatic and asymptomatic carriers of dopa-responsive dystonia measured with [11C]-raclopride and positron-emission tomography.
Neurology 1998;50(4):1028-32.
1997: A Kishore; IM Turnbull; BJ Snow; Raul de la Fuente-Fernandez; Michael Schulzer; Edwin Mak; S Yardley; Donald B Calne
Efficacy, stability and predictors of outcome of pallidotomy for Parkinson's disease. Six-month follow-up with additional 1-year observations.
Brain : a journal of neurology 1997;120 ( Pt 5)():729-37.
1997: Ryan Uitti; H Shinotoh; M Hayward; Michael Schulzer; Edwin Mak; Donald B Calne
"Familial Parkinson's disease"--a case-control study of families.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1997;24(2):127-32.
1996: Susan M Calne; Michael Schulzer; Edwin Mak; C Guyette; G Rohs; S Hatchard; D Murphy; J Hodder; C Gagnon; S Weatherby; L Beaudet; J Duff; S Pegler
Validating a quality of life rating scale for idiopathic parkinsonism: Parkinson's Impact Scale (PIMS).
Parkinsonism & related disorders 1996;2(2):55-61.
1995: J K Tsui; M Hayward; Edwin Mak; Michael Schulzer
Botulinum toxin type B in the treatment of cervical dystonia: a pilot study.
Neurology 1995;45(11):2109-10.
1995: C S Lee; Michael Schulzer; Edwin Mak; John P Hammerstad; S Calne; Donald B Calne
Patterns of asymmetry do not change over the course of idiopathic parkinsonism: implications for pathogenesis.
Neurology 1995;45(3 Pt 1):435-9.
1994: FJ Vingerhoets; BJ Snow; C S Lee; Michael Schulzer; Edwin Mak; Donald B Calne
Longitudinal fluorodopa positron emission tomographic studies of the evolution of idiopathic parkinsonism.
Annals of neurology 1994;36(5):759-64.
1994: Michael Schulzer; C S Lee; Edwin Mak; FJ Vingerhoets; Donald B Calne
A mathematical model of pathogenesis in idiopathic parkinsonism.
Brain : a journal of neurology 1994;117 ( Pt 3)():509-16.
1994: C S Lee; Michael Schulzer; Edwin Mak; BJ Snow; J K Tsui; S Calne; John P Hammerstad; Donald B Calne
Clinical observations on the rate of progression of idiopathic parkinsonism.
Brain : a journal of neurology 1994;117 ( Pt 3)():501-7.
1994: John P Hammerstad; K Elliott; Edwin Mak; Michael Schulzer; S Calne; Donald B Calne
Tendon jerks in Parkinson's disease.
Journal of neural transmission. Parkinson's disease and dementia section 1994;8(1-2):123-30.
1993: Michael Schulzer; Donald B Calne; B Snow; Edwin Mak
A scoring error in the Mini-Mental State test.
Canadian journal of psychiatry. Revue canadienne de psychiatrie 1993;38(9):603-5.
1993: Andrew Eisen; Michael Schulzer; B Pant; M MacNeil; H Stewart; S Trueman; Edwin Mak
Receiver operating characteristic curve analysis in the prediction of carpal tunnel syndrome: a model for reporting electrophysiological data.
Muscle & nerve 1993;16(7):787-96.
1993: Andrew Eisen; Michael Schulzer; M MacNeil; B Pant; Edwin Mak
Duration of amyotrophic lateral sclerosis is age dependent.
Muscle & nerve 1993;16(1):27-32.
1992: Michael Schulzer; Edwin Mak; Donald B Calne
The antiparkinson efficacy of deprenyl derives from transient improvement that is likely to be symptomatic.
Annals of neurology 1992;32(6):795-8.
1990: Erik C Wolters; T A Hurwitz; Edwin Mak; Phillip A Teal; F R Peppard; Ronald Remick; S Calne; Donald B Calne
Clozapine in the treatment of parkinsonian patients with dopaminomimetic psychosis.
Neurology 1990;40(5):832-4.
1989: H Teräväinen; J K Tsui; Edwin Mak; Donald B Calne
Optimal indices for testing parkinsonian rigidity.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1989;16(2):180-3.
1988: Erik C Wolters; J C Kebabian; M Guttman; Edwin Mak; B D Pate; Donald B Calne
A new device for the quantitative assessment of dopaminergic drug effects in unilateral MPTP-lesioned monkeys.
Neuroscience letters 1988;95(1-3):257-61.
1985: A Jon Stoessl; Edwin Mak; Donald B Calne
(+)-4-Propyl-9-hydroxynaphthoxazine (PHNO), a new dopaminomimetic, in treatment of parkinsonism.
Lancet 1985;2(8468):1330-1.
1985: J K Tsui; Andrew Eisen; Edwin Mak; J Carruthers; A Scott; Donald B Calne
A pilot study on the use of botulinum toxin in spasmodic torticollis.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1985;12(4):314-6.