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Tak Wah Mak
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Research Profile (preview)
Chemicals & Drugs
Living Beings
Genes & Molecular Sequences
Physiology
Anatomy
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Network (preview)
8
Hamada, Koichi
8
Nakano, Toru
8
Sasaki, Takehiko
8
Suzuki, Akira
7
Kishimoto, Hiroyuki
5
Horie, Yasuo
4
Yajima, Nobuyuki
4
Suzuki, Akira
4
Nakano, Toru
3
Takeda, Junji
3
Sasaki, Masato
3
Kondoh, Gen
3
Komazawa, Nobuyasu
3
Natsui, Miyuki
2
Manabe, Motomu
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Publications
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Geonetwork of Tak Wah Mak (preview)
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All Publications
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2008: Yuen Hiu-Fung; Chan Yuen-Piu; Law Simon; Srivastava Gopesh; El-Tanani Mohamed; Mak Tak-Wah; Chan Kwok-Wah
DJ-1 could predict worse prognosis in esophageal squamous cell carcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(12):3593-602.
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2008: Kanungo Anish Kumar; Hao Zhenyue; Elia Andrew James; Mak Tak Wah; Henderson Jeffrey Theodore
Inhibition of apoptosome activation protects injured motor neurons from cell death.
The Journal of biological chemistry 2008;283(32):22105-12.
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2008: Inoue-Narita Tae; Hamada Koichi; Sasaki Takehiko; Hatakeyama Sachiko; Fujita Sachiko; Kawahara Kohichi; Sasaki Masato; Kishimoto Hiroyuki; Eguchi Satoshi; Kojima Itaru; Beermann Friedrich; Kimura Tetsunori; Osawa Masatake; Itami Satoshi; Mak Tak Wah; Nakano Toru; Manabe Motomu; Suzuki Akira
Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis.
Cancer research 2008;68(14):5760-8.
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2008: Ueno Takashi; Sato Wataru; Horie Yasuo; Komatsu Masaaki; Tanida Isei; Yoshida Mitsutaka; Ohshima Shigetoshi; Mak Tak Wah; Watanabe Sumio; Kominami Eiki
Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation.
Autophagy 2008;4(5):692-700.
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2008: Suzuki Akira; Nakano Toru; Mak Tak Wah; Sasaki Takehiko
Portrait of PTEN: messages from mutant mice.
Cancer science 2008;99(2):209-13.
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2007: Mak Tak Wah
Gene targeting in embryonic stem cells scores a knockout in Stockholm.
Cell 2007;131(6):1027-31.
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2007: Yanagi Shigehisa; Kishimoto Hiroyuki; Kawahara Kohichi; Sasaki Takehiko; Sasaki Masato; Nishio Miki; Yajima Nobuyuki; Hamada Koichi; Horie Yasuo; Kubo Hiroshi; Whitsett Jeffrey A; Mak Tak Wah; Nakano Toru; Nakazato Masamitsu; Suzuki Akira
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.
The Journal of clinical investigation 2007;117(10):2929-40.
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2007: Kishimoto Hiroyuki; Ohteki Toshiaki; Yajima Nobuyuki; Kawahara Koichi; Natsui Miyuki; Kawarasaki Satoru; Hamada Koichi; Horie Yasuo; Kubo Yoshiaki; Arase Seiji; Taniguchi Masaru; Vanhaesebroeck Bart; Mak Tak Wah; Nakano Toru; Koyasu Shigeo; Sasaki Takehiko; Suzuki Akira
The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells.
Blood 2007;109(8):3316-24.
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2006: Tsuruta Hiroshi; Kishimoto Hiroyuki; Sasaki Takehiko; Horie Yasuo; Natsui Miyuki; Shibata Yoshiko; Hamada Koichi; Yajima Nobuyuki; Kawahara Koichi; Sasaki Masato; Tsuchiya Norihiko; Enomoto Katsuhiko; Mak Tak Wah; Nakano Toru; Habuchi Tomonori; Suzuki Akira
Hyperplasia and carcinomas in Pten-deficient mice and reduced PTEN protein in human bladder cancer patients.
Cancer research 2006;66(17):8389-96.
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2006: You Han; Yamamoto Kazuo; Mak Tak Wah
Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9051-6.
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2005: Hamada Koichi; Sasaki Takehiko; Koni Pandelakis A; Natsui Miyuki; Kishimoto Hiroyuki; Sasaki Junko; Yajima Nobuyuki; Horie Yasuo; Hasegawa Go; Naito Makoto; Miyazaki Jun-Ichi; Suda Toshio; Itoh Hiroshi; Nakao Kazuwa; Mak Tak Wah; Nakano Toru; Suzuki Akira
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis.
Genes & development 2005;19(17):2054-65.
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2005: Tsuchihara Katsuya; Lapin Valentina; Bakal Christopher; Okada Hitoshi; Brown Lauren; Hirota-Tsuchihara Masami; Zaugg Kathrin; Ho Alexandra; Itie-Youten Annick; Harris-Brandts Marees; Rottapel Robert; Richardson Christopher D; Benchimol Samuel; Mak Tak Wah
Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner.
Cancer research 2005;65(15):6685-91.
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2005: Komazawa N; Matsuda M; Kondoh G; Mizunoya W; Iwaki M; Takagi T; Sumikawa Y; Inoue K; Suzuki A; Mak T W; Nakano T; Fushiki T; Takeda J; Shimomura I
Retraction: Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppression in mice.
Nature medicine 2005;11(6):690.
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2004: Komazawa Nobuyasu; Matsuda Morihiro; Kondoh Gen; Mizunoya Wataru; Iwaki Masanori; Takagi Toshiyuki; Sumikawa Yasuyuki; Inoue Kazuo; Suzuki Akira; Mak Tak Wah; Nakano Toru; Fushiki Tohru; Takeda Junji; Shimomura Iichiro
Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppression in mice.
Nature medicine 2004;10(11):1208-15.
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2004: Komazawa Nobuyasu; Suzuki Akira; Sano Shigetoshi; Horie Kyoji; Matsuura Nariaki; Mak Tak Wah; Nakano Toru; Takeda Junji; Kondoh Gen
Tumorigenesis facilitated by Pten deficiency in the skin: evidence of p53-Pten complex formation on the initiation phase.
Cancer science 2004;95(8):639-43.
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2004: Horie Yasuo; Suzuki Akira; Kataoka Ei; Sasaki Takehiko; Hamada Koichi; Sasaki Junko; Mizuno Katsunori; Hasegawa Go; Kishimoto Hiroyuki; Iizuka Masahiro; Naito Makoto; Enomoto Katsuhiko; Watanabe Sumio; Mak Tak Wah; Nakano Toru
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas.
The Journal of clinical investigation 2004;113(12):1774-83.
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2003: Luftig Micah; Prinarakis Efthimios; Yasui Teruhito; Tsichritzis Theodore; Cahir-McFarland Ellen; Inoue Jun-Ichiro; Nakano Hiroyasu; Mak Tak Wah; Yeh Wen-Chen; Li Xiaoxia; Akira Shizuo; Suzuki Nobutaka; Suzuki Shinobu; Mosialos George; Kieff Elliott
Epstein-Barr virus latent membrane protein 1 activation of NF-kappaB through IRAK1 and TRAF6.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15595-600.
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2003: Kondo Seiji; Lu Ying; Debbas Michael; Lin Athena W; Sarosi Ildiko; Itie Annick; Wakeham Andrew; Tuan JoAnn; Saris Chris; Elliott Gary; Ma Weili; Benchimol Samuel; Lowe Scott W; Mak Tak Wah; Thukral Sushil K
Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1).
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5431-6.
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2003: Suzuki Akira; Kaisho Tsuneyasu; Ohishi Minako; Tsukio-Yamaguchi Manae; Tsubata Takeshi; Koni Pandelakis A; Sasaki Takehiko; Mak Tak Wah; Nakano Toru
Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.
The Journal of experimental medicine 2003;197(5):657-67.
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2003: Kishimoto Hiroyuki; Hamada Koichi; Saunders Mary; Backman Stephanie; Sasaki Takehiko; Nakano Toru; Mak Tak Wah; Suzuki Akira
Physiological functions of Pten in mouse tissues.
Cell structure and function 2003;28(1):11-21.
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2003: Suzuki Akira; Itami Satoshi; Ohishi Minako; Hamada Koichi; Inoue Tae; Komazawa Nobuyasu; Senoo Haruki; Sasaki Takehiko; Takeda Junji; Manabe Motomu; Mak Tak Wah; Nakano Toru
Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation.
Cancer research 2003;63(3):674-81.
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