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Kauko Mäkinen
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32
Mäkinen, Pirkko-Liisa
21
Söderling, Eva
17
Isotupa, Kauko
8
Hujoel, Philippe
5
Tenovuo, Jorma
5
Tiekso, Jaakko
3
Alanen, Pentti
3
Loesche, Walter
2
Lopatin, Dennis
2
Olak, Jana
2
Saag, Mare
2
Hämäläinen, MM
2
Lamont, Richard
1
Jeong, Seong Hwa
1
Karjalainen, Sára
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All Publications
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2009: Mäkinen K K
An end to crossover designs for studies on the effect of sugar substitutes on caries?
Caries research 2009;43(5):331-3.
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2008: Mäkinen Kauko K; Alanen Pentti; Isokangas Pauli; Isotupa Kauko; Söderling Eva; Mäkinen Pirkko-Liisa; Wenhui Wang; Weijian Wang; Xiaochi Chen; Yi Wei; Boxue Zhang
Thirty-nine-month xylitol chewing-gum programme in initially 8-year-old school children: a feasibility study focusing on mutans streptococci and lactobacilli.
International dental journal 2008;58(1):41-50.
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2005: Mäkinen K K; Saag M; Isotupa K P; Olak J; Nõmmela R; Söderling E; Mäkinen P-L
Similarity of the effects of erythritol and xylitol on some risk factors of dental caries.
Caries research 2005;39(3):207-15.
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2005: Mäkinen Kauko K; Isotupa Kauko P; Mäkinen Pirkko-Liisa; Söderling Eva; Song Keun Bae; Nam Soon Hyeun; Jeong Seong Hwa
Six-month polyol chewing-gum programme in kindergarten-age children: a feasibility study focusing on mutans streptococci and dental plaque.
International dental journal 2005;55(2):81-8.
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2002: Mäkinen Kauko K; Isotupa Kauko P; Kivilompolo Taina; Mäkinen Pirkko-Liisa; Murtomaa Satu; Petäjä Juhani; Toivanen Jukka; Söderling Eva
The effect of polyol-combinant saliva stimulants on S. mutans levels in plaque and saliva of patients with mental retardation.
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 2002;22(5):187-93.
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2002: Peldyak John; Mäkinen Kauko K
Xylitol for caries prevention.
Journal of dental hygiene : JDH / American Dental Hygienists' Association 2002;76(4):276-85.
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2001: Mäkinen K K; Isotupa K P; Kivilompolo T; Mäkinen P L; Toivanen J; Söderling E
Comparison of erythritol and xylitol saliva stimulants in the control of dental plaque and mutans streptococci.
Caries research 2001;35(2):129-35.
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2000: Mäkinen K K
Can the pentitol-hexitol theory explain the clinical observations made with xylitol?
Medical hypotheses 2000;54(4):603-13.
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1999: Hujoel P P; Mäkinen K K; Bennett C A; Isotupa K P; Isokangas P J; Allen P; Mäkinen P L
The optimum time to initiate habitual xylitol gum-chewing for obtaining long-term caries prevention.
Journal of dental research 1999;78(3):797-803.
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1998: Mäkinen K K; Chiego D J; Allen P; Bennett C; Isotupa K P; Tiekso J; Mäkinen P L
Physical, chemical, and histologic changes in dentin caries lesions of primary teeth induced by regular use of polyol chewing gums.
Acta odontologica Scandinavica 1998;56(3):148-56.
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1998: Mäkinen K K; Olak J; Russak S; Saag M; Seedre T; Vasar R; Vihalemm T; Mikelsaar M; Mäkinen P L
Polyol-combinant saliva stimulants: a 4-month pilot study in young adults.
Acta odontologica Scandinavica 1998;56(2):90-4.
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1998: Mäkinen K K; Hujoel P P; Bennett C A; Isokangas P; Isotupa K; Pape H R; Mäkinen P L
A descriptive report of the effects of a 16-month xylitol chewing-gum programme subsequent to a 40-month sucrose gum programme.
Caries research 1998;32(2):107-12.
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1997: Mäkinen P L; Mäkinen K K
gamma-Glutamyltransferase from the outer cell envelope of Treponema denticola ATCC 35405.
Infection and immunity 1997;65(2):685-91.
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1996: Mäkinen K K; Pemberton D; Mäkinen P L; Chen C Y; Cole J; Hujoel P P; Lopatin D; Lambert P
Polyol-combinant saliva stimulants and oral health in Veterans Affairs patients--an exploratory study.
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 1996;16(3):104-15.
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1996: Mäkinen K K; Mäkinen P L
The peptidolytic capacity of the spirochete system.
Medical microbiology and immunology 1996;185(1):1-10.
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1996: Mäkinen K K; Chen C Y; Mäkinen P L
Proline iminopeptidase from the outer cell envelope of the human oral spirochete Treponema denticola ATCC 35405.
Infection and immunity 1996;64(3):702-8.
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1996: Mäkinen K K; Mäkinen P L; Pape H R; Peldyak J; Hujoel P; Isotupa K P; Soderling E; Isokangas P J; Allen P; Bennett C
Conclusion and review of the Michigan Xylitol Programme (1986-1995) for the prevention of dental caries.
International dental journal 1996;46(1):22-34.
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1996: Mäkinen K K; Sewon L; Mäkinen P l
Analysis in gingival crevicular fluid of two oligopeptides derived from human hemoglobin beta-chain.
Journal of periodontal research 1996;31(1):43-6.
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1996: Mäkinen K K; Hujoel P P; Bennett C A; Isotupa K P; Mäkinen P L; Allen P
Polyol chewing gums and caries rates in primary dentition: a 24-month cohort study.
Caries research 1996;30(6):408-17.
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1996: Mäkinen K K; Chen C Y; Mäkinen P L; Bennett C A; Isokangas P J; Isotupa K P; Pape H R
Properties of whole saliva and dental plaque in relation to 40-month consumption of chewing gums containing xylitol, sorbitol of sucrose.
Caries research 1996;30(3):180-8.
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1995: Mäkinen K K; Bennett C A; Hujoel P P; Isokangas P J; Isotupa K P; Pape H R; Mäkinen P L
Xylitol chewing gums and caries rates: a 40-month cohort study.
Journal of dental research 1995;74(12):1904-13.
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1995: Mäkinen P L; Mäkinen K K; Syed S A
Role of the chymotrypsin-like membrane-associated proteinase from Treponema denticola ATCC 35405 in inactivation of bioactive peptides.
Infection and immunity 1995;63(9):3567-75.
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1995: Mäkinen K K; Pemberton D; Cole J; Mäkinen P L; Chen C Y; Lambert P
Saliva stimulants and the oral health of geriatric patients.
Advances in dental research 1995;9(2):125-6.
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1995: Isotupa K P; Gunn S; Chen C Y; Lopatin D; Mäkinen K K
Effect of polyol gums on dental plaque in orthodontic patients.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 1995;107(5):497-504.
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1995: Mäkinen K K; Mäkinen P L; Loesche W J; Syed S A
Purification and general properties of an oligopeptidase from Treponema denticola ATCC 35405--a human oral spirochete.
Archives of biochemistry and biophysics 1995;316(2):689-98.
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1995: Mäkinen K K; Mäkinen P L; Pape H R; Allen P; Bennett C A; Isokangas P J; Isotupa K P
Stabilisation of rampant caries: polyol gums and arrest of dentine caries in two long-term cohort studies in young subjects.
International dental journal 1995;45(1 Suppl 1):93-107.
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1995: Hujoel P P; Mäkinen K K; Bennett C B; Isokangas P J; Isotupa K P; Pape H R; Lamont R J; DeRouen T A; Davis S
Do caries explorers transmit infections with persons? An evaluation of second molar caries onsets.
Caries research 1995;29(6):461-6.
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1994: Pape H R; Mäkinen K K
Verification and maintenance of dental explorer sharpness.
Operative dentistry 1994;19(6):221-3.
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1994: Mäkinen P L; Mäkinen K K; Syed S A
An endo-acting proline-specific oligopeptidase from Treponema denticola ATCC 35405: evidence of hydrolysis of human bioactive peptides.
Infection and immunity 1994;62(11):4938-47.
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1994: Mäkinen P L; Mäkinen K K
The Enterococcus faecalis extracellular metalloendopeptidase (EC 3.4.24.30; coccolysin) inactivates human endothelin at bonds involving hydrophobic amino acid residues.
Biochemical and biophysical research communications 1994;200(2):981-5.
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1994: Hujoel P P; Isokangas P J; Tiekso J; Davis S; Lamont R J; DeRouen T A; Mäkinen K K
A re-analysis of caries rates in a preventive trial using Poisson regression models.
Journal of dental research 1994;73(2):573-9.
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1993: Syed S A; Mäkinen K K; Mäkinen P L; Chen C Y; Muhammad Z
Proteolytic and oxidoreductase activity of Treponema denticola ATCC 35405 grown in an aerobic and anaerobic gaseous environment.
Research in microbiology 1993;144(4):317-26.
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1993: Mäkinen K K
A dietary procedure for preventing dental caries in young adults.
Journal of American college health : J of ACH 1993;41(4):172-80.
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1993: Isogangas P; Mäkinen K K; Tiekso J; Alanen P
Long-term effect of xylitol chewing gum in the prevention of dental caries: a follow-up 5 years after termination of a prevention program.
Caries research 1993;27(6):495-8.
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1992: Isotupa K P; Carlson D S; Mäkinen K K
Influence of asymmetric occlusal relationships and decreased maxillary width on the growth of the facial skeleton in the guinea pig.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 1992;174(5):447-51.
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1992: Isotupa K P; Mäkinen K K; Carlson D S
Proteinase, phosphatase and glucuronidase activities in the growing mandible and temporomandibular joint of the guinea pig.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 1992;174(5):441-6.
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1992: Mäkinen K K; Mäkinen P L; Syed S A
Purification and substrate specificity of an endopeptidase from the human oral spirochete Treponema denticola ATCC 35405, active on furylacryloyl-Leu-Gly-Pro-Ala and bradykinin.
The Journal of biological chemistry 1992;267(20):14285-93.
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1991: Söderling E; Mäkinen P L; Syed S; Mäkinen K K
Biochemical comparison of proteolytic enzymes present in rough- and smooth-surfaced capnocytophagas isolated from the subgingival plaque of periodontitis patients.
Journal of periodontal research 1991;26(1):17-23.
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1991: Söderling E; Isokangas P; Tenovuo J; Mustakallio S; Mäkinen K K
Long-term xylitol consumption and mutans streptococci in plaque and saliva.
Caries research 1991;25(2):153-7.
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1991: Isokangas P; Tenovuo J; Söderling E; Männistö H; Mäkinen K K
Dental caries and mutans streptococci in the proximal areas of molars affected by the habitual use of xylitol chewing gum.
Caries research 1991;25(6):444-8.
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1990: Mäkinen K K; Chen C Y; Mäkinen P L; Ohta K; Loesche W J
The benzoylarginine peptidase from Treponema denticola (strain ASLM), a human oral spirochaete: evidence for active-site carboxyl groups.
Molecular microbiology 1990;4(8):1413-7.
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1990: Pihlanto-Leppälä A; Söderling E; Mäkinen K K
Expulsion mechanism of xylitol 5-phosphate in Streptococcus mutans.
Scandinavian journal of dental research 1990;98(2):112-9.
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1989: Karjalainen S; Hannula P; Söderling E; Hämäläinen M; Mäkinen K; Scheinin A
Sucrose consumption and salivary sucrase activity in a 2-year longitudinal study.
Scandinavian journal of dental research 1989;97(5):401-4.
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1989: Isokangas P; Tiekso J; Alanen P; Mäkinen K K
Long-term effect of xylitol chewing gum on dental caries.
Community dentistry and oral epidemiology 1989;17(4):200-3.
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1989: Mäkinen K K; Söderling E; Peacor D R; Mäkinen P L; Park L M
Carbohydrate-controlled precipitation of apatite with coprecipitation of organic molecules in human saliva: stabilizing role of polyols.
Calcified tissue international 1989;44(4):258-68.
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1989: Mäkinen P L; Clewell D B; An F; Mäkinen K K
Purification and substrate specificity of a strongly hydrophobic extracellular metalloendopeptidase ("gelatinase") from Streptococcus faecalis (strain 0G1-10).
The Journal of biological chemistry 1989;264(6):3325-34.
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1989: Mäkinen K K; Söderling E; Isokangas P; Tenovuo J; Tiekso J
Oral biochemical status and depression of Streptococcus mutans in children during 24- to 36-month use of xylitol chewing gum.
Caries research 1989;23(4):261-7.
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1989: Söderling E; Mäkinen K K; Chen C Y; Pape H R; Loesche W; Mäkinen P L
Effect of sorbitol, xylitol, and xylitol/sorbitol chewing gums on dental plaque.
Caries research 1989;23(5):378-84.
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1989: Pihlanto-Leppälä A; Söderling E; Mäkinen K
Uptake of 14C-xylitol by xylitol-cultured Streptococcus sobrinus ATCC 27352 and Streptococcus mitis ATCC 36249 in vitro.
Proceedings of the Finnish Dental Society. Suomen Hammaslääkäriseuran toimituksia 1989;85(6):423-8.
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1989: Hämäläinen M M; Mäkinen K K
Relationship between mineral metabolism and peroral consumption of sugar alcohols.
Mineral and electrolyte metabolism 1989;15(6):346-52.
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1988: Mäkinen K K; Virtanen K K; Mäkinen P L; Kotiranta J
Free amino acids in human palatine gland secretions.
Archives of oral biology 1988;33(11):847-9.
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1987: Söderling E; Talonpoika J; Mäkinen K K
Effect of xylitol-containing carbohydrate mixtures on acid and ammonia production in suspensions of salivary sediment.
Scandinavian journal of dental research 1987;95(5):405-10.
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1985: Mäkinen K K; Virtanen K K; Söderling E; Kotiranta J
Effect of xylitol-, sucrose-, and water-rinses on the composition of human palatine gland secretions.
Scandinavian journal of dental research 1985;93(3):253-61.
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1985: Hämäläinen M M; Mäkinen K K; Parviainen M T; Koskinen T
Peroral xylitol increases intestinal calcium absorption in the rat independently of vitamin D action.
Mineral and electrolyte metabolism 1985;11(3):178-81.
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1985: Mäkinen K K; Söderling E; Virtanen K K; Kotiranta J
Partial purification and characterization of arylamidases from human palatine secretions.
Archives of oral biology 1985;30(7):513-7.
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1984: Mäkinen K K; Virtanen K K; Mäkinen P L; Söderling E; Neva M; Sinisalo T; Kölling D
Effect of single doses of sucrose and xylitol on human parotid saliva.
Proceedings of the Finnish Dental Society. Suomen Hammaslääkäriseuran toimituksia 1984;80(4):186-200.
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1984: Paunio K; Hurttia H; Tenovuo J; Mäkinen K K; Tiekso J
Effects on oral health of mouthrinses containing xylitol, sodium cyclamate and sucrose sweeteners in the absence of oral hygiene. I. Clinical findings and analysis of gingival exudate.
Proceedings of the Finnish Dental Society. Suomen Hammaslääkäriseuran toimituksia 1984;80(1):3-12.
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1984: Hurttia H; Multanen V M; Mäkinen K K; Tenovuo J; Paunio K
Effects on oral health of mouthrinses containing xylitol, sodium cyclamate and sucrose sweeteners in the absence of oral hygiene. III. Composition and bone resorbing potential of dental plaque.
Proceedings of the Finnish Dental Society. Suomen Hammaslääkäriseuran toimituksia 1984;80(1):20-7.
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1984: Mäkinen K K; Hurttia H; Mäkinen P L; Paunio K
Effects on oral health of mouthrinses containing xylitol, sodium cyclamate and sucrose sweeteners in the absence of oral hygiene. II. Relative composition of free amino acids in human crevicular fluid.
Proceedings of the Finnish Dental Society. Suomen Hammaslääkäriseuran toimituksia 1984;80(1):13-9.
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1983: Mäkinen K K; Söderling E; Kölling D
Secretory activity of salivary gland slices in the presence of polyols.
Proceedings of the Finnish Dental Society. Suomen Hammaslääkäriseuran toimituksia 1983;79(5-6):218-23.
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1983: Mäkinen K K; Virtanen K K; Söderling E; Kotiranta J
Composition of human palatine gland secretions and evidence for the presence of specific arylamidases.
Archives of oral biology 1983;28(9):893-4.
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1981: Mäkinen K K; Kölling D; Mäkinen P L
The effect of high oral dosage of xylitol and sucrose on the biochemical properties of whole saliva in human volunteers after long-term regular consumption of xylitol.
Proceedings of the Finnish Dental Society. Suomen Hammaslääkäriseuran toimituksia 1981;77(5):262-70.
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1980: Mäkinen K K; Kölling D; Söderling E
Exocrine gland enzyme levels after peroral administration of xylitol and sorbitol in the rat.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 1980;50(1):79-83.
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