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Michael Malamy

Research Profile

Living Beings

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Genes & Molecular Sequences

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Cloning, Molecular

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Mutagenesis, Insertional

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Publications

TOP 3
Brian M Meehan; Anthony D Baughn; Rene Gallegos; Michael H Malamy
Inactivation of a single gene enables microaerobic growth of the obligate anaerobe Bacteroides fragilis.
Brian M Meehan; Michael H Malamy
Fumarate reductase is a major contributor to the generation of reactive oxygen species in the anaerobe Bacteroides fragilis.
Christopher Brigham; Ruth Caughlan; Rene Gallegos; Mary Beth Dallas; Veronica G Godoy; Michael H Malamy
Sialic acid (N-acetyl neuraminic acid) utilization by Bacteroides fragilis requires a novel N-acetyl mannosamine epimerase.

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All Publications

2012: Brian M Meehan; Anthony D Baughn; Rene Gallegos; Michael H Malamy
Inactivation of a single gene enables microaerobic growth of the obligate anaerobe Bacteroides fragilis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(30):12153-8.
2012: Brian M Meehan; Michael H Malamy
Fumarate reductase is a major contributor to the generation of reactive oxygen species in the anaerobe Bacteroides fragilis.
Microbiology (Reading, England) 2012;158(Pt 2):539-46.
2009: Christopher Brigham; Ruth Caughlan; Rene Gallegos; Mary Beth Dallas; Veronica G Godoy; Michael H Malamy
Sialic acid (N-acetyl neuraminic acid) utilization by Bacteroides fragilis requires a novel N-acetyl mannosamine epimerase.
Journal of bacteriology 2009;191(11):3629-38.
2006: Dashuang Shi; Hiroki Morizono; Juan Cabrera-Luque; Xiaolin Yu; Lauren Roth; Michael H Malamy; Norma M Allewell; Mendel Tuchman
Structure and catalytic mechanism of a novel N-succinyl-L-ornithine transcarbamylase in arginine biosynthesis of Bacteroides fragilis.
The Journal of biological chemistry 2006;281(29):20623-31.
2006: Hiroki Morizono; Juan Cabrera-Luque; Dashuang Shi; Rene Gallegos; Saori Yamaguchi; Xiaolin Yu; Norma M Allewell; Michael H Malamy; Mendel Tuchman
Acetylornithine transcarbamylase: a novel enzyme in arginine biosynthesis.
Journal of bacteriology 2006;188(8):2974-82.
2005: Dashuang Shi; Hiroki Morizono; Xiaolin Yu; Lauren Roth; Ljubica Caldovic; Norma M Allewell; Michael H Malamy; Mendel Tuchman
Crystal structure of N-acetylornithine transcarbamylase from Xanthomonas campestris: a novel enzyme in a new arginine biosynthetic pathway found in several eubacteria.
The Journal of biological chemistry 2005;280(15):14366-9.
2005: Christopher J Brigham; Michael H Malamy
Characterization of the RokA and HexA broad-substrate-specificity hexokinases from Bacteroides fragilis and their role in hexose and N-acetylglucosamine utilization.
Journal of bacteriology 2005;187(3):890-901.
2004: Anthony D Baughn; Michael H Malamy
The strict anaerobe Bacteroides fragilis grows in and benefits from nanomolar concentrations of oxygen.
Nature 2004;427(6973):441-4.
2003: Anthony D Baughn; Michael H Malamy
The essential role of fumarate reductase in haem-dependent growth stimulation of Bacteroides fragilis.
Microbiology (Reading, England) 2003;149(Pt 6):1551-8.
2002: Ljubica Caldovic; Hiroki Morizono; Maria Gracia Panglao; Rene Gallegos; Xiaolin Yu; Dashuang Shi; Michael H Malamy; Norma M Allewell; Mendel Tuchman
Cloning and expression of the human N-acetylglutamate synthase gene.
Biochemical and biophysical research communications 2002;299(4):581-6.
2002: Dashuang Shi; Rene Gallegos; Joseph DePonte; Hiroki Morizono; Xiaolin Yu; Norma M Allewell; Michael H Malamy; Mendel Tuchman
Crystal structure of a transcarbamylase-like protein from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution.
Journal of molecular biology 2002;320(4):899-908.
2002: Ljubica Caldovic; Hiroki Morizono; Xiaolin Yu; Mark Thompson; Dashuang Shi; Rene Gallegos; Norma M Allewell; Michael H Malamy; Mendel Tuchman
Identification, cloning and expression of the mouse N-acetylglutamate synthase gene.
The Biochemical journal 2002;364(Pt 3):825-31.
2002: Anthony D Baughn; Michael H Malamy
A mitochondrial-like aconitase in the bacterium Bacteroides fragilis: implications for the evolution of the mitochondrial Krebs cycle.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4662-7.
2000: Tsute Chen; H Dong; YP Tang; M M Dallas; Michael H Malamy; Margaret J Duncan
Identification and cloning of genes from Porphyromonas gingivalis after mutagenesis with a modified Tn4400 transposon from Bacteroides fragilis.
Infection and immunity 2000;68(1):420-3.
2000: YP Tang; Michael H Malamy
Isolation of Bacteroides fragilis mutants with in vivo growth defects by using Tn4400', a modified Tn4400 transposition system, and a new screening method.
Infection and immunity 2000;68(1):415-9.
1999: YP Tang; M M Dallas; Michael H Malamy
Characterization of the Batl (Bacteroides aerotolerance) operon in Bacteroides fragilis: isolation of a B. fragilis mutant with reduced aerotolerance and impaired growth in in vivo model systems.
Molecular microbiology 1999;32(1):139-49.
1998: Raj Rajagopal; J DePonte; Mendel Tuchman; Michael H Malamy
Use of inducible feedback-resistant N-acetylglutamate synthetase (argA) genes for enhanced arginine biosynthesis by genetically engineered Escherichia coli K-12 strains.
Applied and environmental microbiology 1998;64(5):1805-11.
1997: Mendel Tuchman; Raj Rajagopal; MT McCann; Michael H Malamy
Enhanced production of arginine and urea by genetically engineered Escherichia coli K-12 strains.
Applied and environmental microbiology 1997;63(1):33-8.